NUP188 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NUP188
Entrez Gene ID	23511
Full Name	nucleoporin 188
Synonyms	KIAA0169,hNup188
General protein information	Preferred Names nucleoporin 188 Names nucleoporin NUP188 homolog nucleoporin 188kDa
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9q34.11
Summary	The nuclear pore complex (NPC) is found on the nuclear envelope and forms a gateway that regulates the flow of proteins and RNAs between the cytoplasm and nucleoplasm. The NPC is comprised of approximately 30 distinct proteins collectively known as nucleoporins. Nucleoporins are pore-complex-specific glycoproteins which often have cytoplasmically oriented O-linked N-acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. However, the nucleoporin protein encoded by this gene does not contain the typical FG repeat sequences found in most vertebrate nucleoporins. This nucleoporin is thought to form part of the scaffold for the central channel of the nuclear pore. [provided by RefSeq, Jan 2013].
Disorder MIM:	615587

mRNA and Protein(s)

mRNA	Protein	Name
NM_015354.3	NP_056169.1	nucleoporin NUP188 homolog
NM_015354.2	NP_056169.1	nucleoporin NUP188 homolog

Pathways from BioSystems

Homologies

Homo sapiens (human)	NUP188	NP_056169.1
Canis lupus familiaris (dog)	NUP188	XP_005625319.1
Mus musculus (house mouse)	Nup188	NP_938046.2
Rattus norvegicus (Norway rat)	Nup188	XP_006233967.1
	NUP188	XP_002800020.1
Bos taurus (cattle)	NUP188	NP_001095308.1
Danio rerio (zebrafish)	nup188	XP_001923018.1
Gallus gallus (chicken)	NUP188	NP_001025861.1
Pan troglodytes (chimpanzee)	NUP188	XP_520414.3
Xenopus tropicalis (tropical clawed frog)	nup188	NP_001107292.1

Gene Ontology
Bibliography

Related articles in PubMed

Congenital Heart Disease Genetics Uncovers Context-Dependent Organization and Function of Nucleoporins at Cilia.
Del Viso F, Huang F, Myers J, Chalfant M, Zhang Y, Reza N, Bewersdorf J, Lusk CP, Khokha MK
Developmental cell38(5)478-92(2016 09)

Mutations in nuclear pore genes NUP93, NUP205 and XPO5 cause steroid-resistant nephrotic syndrome.
Braun DA, Sadowski CE, Kohl S, Lovric S, Astrinidis SA, Pabst WL, Gee HY, Ashraf S, Lawson JA, Shril S, Airik M, Tan W, Schapiro D, Rao J, Choi WI, Hermle T, Kemper MJ, Pohl M, Ozaltin F, Konrad M, Bogdanovic R, B?scher R, Helmchen U, Serdaroglu E, Lifton RP, Antonin W, Hildebrandt F
Nature genetics48(4)457-65(2016 Apr)

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions.
Denoeud F, Kapranov P, Ucla C, Frankish A, Castelo R, Drenkow J, Lagarde J, Alioto T, Manzano C, Chrast J, Dike S, Wyss C, Henrichsen CN, Holroyd N, Dickson MC, Taylor R, Hance Z, Foissac S, Myers RM, Rogers J, Hubbard T, Harrow J, Guig? R, Gingeras TR, Antonarakis SE, Reymond A
Genome research17(6)746-59(2007 Jun)

Identification of a new vertebrate nucleoporin, Nup188, with the use of a novel organelle trap assay.
Miller BR, Powers M, Park M, Fischer W, Forbes DJ
Molecular biology of the cell11(10)3381-96(2000 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

we show that knockdown of Nup188 or its binding partner Nup93 leads to a loss of cilia during embryonic development while leaving NPC function largely intact. Many data, including the localization of endogenous Nup188/93 at cilia bases, support their direct role at cilia. Super-resolution imaging of Nup188 shows two barrel-like structures
Title: Congenital Heart Disease Genetics Uncovers Context-Dependent Organization and Function of Nucleoporins at Cilia.

The following NUP188 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NUP188 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20110	NM_015354.3 Latest version!	Homo sapiens nucleoporin 188 (NUP188), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$951.30 $1359.00
View Old Accession Versions >>
OHu20110	NM_015354.2	Homo sapiens nucleoporin 188 (NUP188), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$951.30 $1359.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NUP188 ( NM_015354.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_056169.1 Homo sapiens nucleoporin 188 (NUP188), mRNA.

Price & Availability↑

CloneID	OHu20110
Clone ID Related Accession (Same CDS sequence)	NM_015354.3 , NM_015354.2
Accession Version	NM_015354.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5250bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	nucleoporin NUP188 homolog
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY094051.1, D79991.1 and AA731883.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_015354.2. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.225471.1, SRR1660809.113796.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000372577.2/ ENSP00000361658.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCGG CCGCCGGCGG GCCGTGTGTG AGGAGCAGTA GAGAACTGTG GACTATTCTG 
CTTGGAAGGT CAGCTCTGAG AGAGCTGAGT CAGATTGAGG CAGAACTGAA TAAACATTGG 
CGGCGATTGT TAGAGGGGCT TTCTTACTAC AAACCTCCCA GTCCAAGTTC AGCTGAAAAA 
GTGAAAGCTA ATAAAGATGT AGCTTCACCA TTGAAGGAAC TGGGTTTAAG AATCAGCAAG 
TTTTTGGGTC TTGATGAAGA ACAGAGTGTG CAGTTACTCC AGTGTTACCT GCAAGAGGAC 
TACAGGGGTA CTCGGGACTC AGTAAAGACA GTACTGCAAG ATGAGAGGCA GAGCCAGGCC 
TTAATCCTGA AGATTGCAGA TTATTATTAT GAAGAAAGAA CCTGTATTCT TCGTTGTGTC 
TTACACCTTC TCACTTACTT CCAAGATGAA AGACACCCCT ATAGGGTTGA ATATGCAGAC 
TGTGTTGATA AATTGGAGAA GGAACTAGTT TCAAAATACA GACAGCAGTT CGAAGAGCTT 
TATAAAACTG AAGCACCAAC TTGGGAGACA CATGGAAATC TCATGACAGA GCGCCAAGTG 
TCTCGCTGGT TTGTTCAGTG CCTTCGGGAA CAGTCCATGC TGCTAGAAAT TATTTTCCTT 
TATTATGCAT ACTTTGAGAT GGCACCCAGT GACTTACTTG TATTAACCAA GATGTTTAAA 
GAGCAAGGAT TTGGTAGTAG GCAGACCAAT AGGCACCTGG TGGATGAGAC TATGGATCCT 
TTTGTAGATC GGATTGGCTA CTTCAGTGCC CTCATCCTGG TGGAGGGCAT GGATATCGAG 
TCCTTGCATA AGTGTGCTTT GGATGACAGA AGAGAACTGC ATCAGTTTGC GCAGGATGGG 
CTTATTTGTC AGGATATGGA CTGTTTAATG TTGACCTTTG GGGACATTCC ACATCATGCC 
CCAGTGCTTT TGGCCTGGGC TCTCCTCCGT CACACTCTGA ACCCAGAAGA GACAAGCAGT 
GTGGTCCGGA AGATAGGTGG CACAGCCATC CAGCTGAATG TGTTTCAGTA CTTGACCCGA 
TTGCTCCAGT CCCTTGCCAG TGGGGGAAAT GATTGCACCA CCAGCACTGC ATGCATGTGT 
GTCTATGGAC TGCTCTCTTT CGTTCTGACC TCGTTGGAGC TGCACACCCT GGGCAATCAG 
CAGGATATAA TTGATACAGC ATGTGAAGTA TTGGCCGACC CTTCTCTTCC GGAACTGTTC 
TGGGGAACAG AGCCAACTTC TGGCCTTGGG ATCATTCTGG ACAGTGTGTG TGGAATGTTT 
CCCCACCTTC TCTCCCCACT CCTGCAACTG CTCCGAGCCC TGGTATCAGG GAAGTCCACA 
GCCAAAAAGG TGTATAGCTT CTTGGATAAG ATGTCTTTCT ACAATGAACT TTATAAACAC 
AAGCCTCATG ATGTGATCTC CCATGAAGAT GGAACTCTTT GGCGGAGACA AACACCCAAA 
CTCCTTTATC CCCTTGGGGG TCAAACCAAC CTTCGCATAC CTCAAGGCAC TGTGGGCCAA 
GTAATGTTGG ATGATAGGGC ATACCTGGTA CGCTGGGAAT ACTCCTATAG CAGCTGGACC 
CTCTTTACCT GCGAGATTGA AATGTTGCTT CATGTTGTTT CAACTGCAGA TGTGATTCAG 
CACTGCCAGC GAGTCAAACC CATCATTGAT CTCGTCCATA AGGTCATCAG TACAGACCTG 
TCGATAGCAG ACTGTCTCCT GCCCATCACA TCTCGCATCT ACATGCTGCT GCAGCGGTTA 
ACGACAGTGA TCTCCCCACC TGTGGATGTC ATTGCTTCTT GTGTCAACTG CTTAACTGTT 
TTGGCTGCCC GCAATCCAGC AAAGGTCTGG ACTGATCTTC GTCACACAGG TTTTTTACCA 
TTTGTGGCCC ATCCTGTCTC CAGCCTGAGT CAGATGATTA GTGCGGAAGG GATGAATGCT 
GGAGGGTACG GAAACCTCTT GATGAACAGT GAACAGCCTC AGGGCGAGTA TGGGGTTACT 
ATTGCCTTTC TGCGCTTGAT CACCACCCTT GTCAAGGGGC AACTTGGTAG TACCCAGAGC 
CAAGGACTTG TACCCTGTGT AATGTTTGTG CTGAAGGAGA TGCTTCCCAG CTACCATAAG 
TGGCGCTACA ACTCTCATGG AGTGAGGGAA CAGATTGGTT GCCTGATCTT GGAGCTGATT 
CATGCGATAC TGAACCTGTG CCACGAGACA GACCTGCACA GCAGTCATAC TCCCAGCCTG 
CAGTTTCTCT GCATCTGCAG CCTGGCATAC ACAGAAGCAG GACAGACAGT TATCAATATC 
ATGGGCATTG GCGTGGACAC CATTGACATG GTGATGGCTG CTCAGCCTCG AAGTGATGGG 
GCAGAGGGCC AGGGGCAGGG CCAGCTGCTG ATCAAGACAG TGAAACTGGC ATTCTCCGTC 
ACCAACAATG TTATTCGGCT GAAACCTCCT TCTAATGTGG TGTCCCCCCT GGAACAGGCT 
CTCTCACAAC ATGGTGCTCA TGGAAACAAC CTCATTGCTG TTCTAGCCAA ATACATCTAC 
CACAAACATG ACCCTGCTTT GCCACGTCTT GCCATTCAGC TGCTGAAACG TCTGGCCACG 
GTGGCCCCAA TGTCAGTGTA TGCTTGTCTG GGCAATGATG CGGCTGCCAT TCGTGATGCC 
TTCCTGACCC GATTGCAGAG CAAAATTGAG GACATGCGCA TCAAAGTCAT GATTCTAGAG 
TTCCTCACTG TTGCAGTAGA GACCCAGCCA GGCCTCATCG AACTGTTTCT GAACCTGGAA 
GTTAAGGATG GCAGTGATGG CTCAAAGGAA TTCAGCCTTG GGATGTGGAG CTGTCTCCAT 
GCAGTGCTGG AGCTGATTGA TTCCCAACAG CAAGATCGAT ACTGGTGCCC ACCCCTGCTG 
CATCGTGCCG CCATTGCCTT TTTGCATGCT CTGTGGCAGG ATCGGAGGGA CAGTGCCATG 
CTGGTCCTCC GAACCAAACC CAAGTTTTGG GAAAATTTAA CCAGTCCGCT GTTTGGAACC 
CTTTCTCCTC CCTCTGAAAC ATCAGAGCCC AGCATCCTGG AAACCTGTGC CCTAATCATG 
AAGATAATTT GCTTGGAGAT ATACTATGTA GTAAAGGGTT CATTAGACCA GTCATTAAAG 
GATACACTGA AGAAATTTTC CATCGAGAAA CGCTTTGCCT ACTGGTCAGG GTATGTCAAG 
TCATTGGCAG TTCACGTGGC CGAAACAGAA GGCAGCAGCT GCACCTCCTT GTTAGAGTAC 
CAGATGCTGG TGTCCGCCTG GAGGATGCTT CTCATCATTG CCACCACTCA TGCAGATATA 
ATGCACCTGA CTGACTCTGT GGTGCGTCGC CAGCTCTTTC TTGACGTGCT TGATGGAACC 
AAAGCATTAC TCCTAGTTCC AGCCTCAGTG AACTGCCTTC GCCTTGGCTC CATGAAGTGC 
ACTCTGCTGC TTATCCTCCT CCGGCAGTGG AAGAGAGAGT TAGGTTCTGT GGATGAAATC 
CTTGGACCCT TGACGGAGAT CCTGGAGGGA GTGCTGCAGG CCGACCAGCA ACTCATGGAG 
AAGACCAAGG CCAAGGTGTT CTCAGCATTC ATCACAGTGT TGCAAATGAA GGAGATGAAA 
GTAAGTGACA TCCCCCAGTA CTCCCAGCTG GTGCTGAATG TCTGTGAGAC CCTCCAAGAG 
GAAGTGATTG CACTCTTCGA CCAGACCCGC CACAGTCTGG CATTAGGCAG TGCCACAGAG 
GACAAGGACA GCATGGAGAC TGACGACTGT TCTCGGTCCC GGCACAGGGA CCAGCGTGAT 
GGGGTGTGTG TCCTGGGCCT GCACCTGGCC AAGGAGCTGT GTGAGGTAGA CGAGGATGGT 
GACTCCTGGC TGCAGGTAAC CCGCAGGCTC CCCATCCTAC CCACCCTCCT CACCACTCTA 
GAGGTGAGCC TTCGCATGAA GCAGAACCTG CATTTCACTG AGGCCACATT GCATCTGCTC 
CTCACCCTGG CTCGCACTCA GCAGGGAGCC ACAGCAGTGG CTGGAGCTGG CATCACCCAG 
AGCATTTGTT TGCCCCTTCT GAGTGTGTAC CAGCTGAGCA CCAACGGCAC AGCACAGACA 
CCTAGTGCCT CTCGGAAGTC CCTGGATGCC CCCTCTTGGC CAGGAGTCTA CCGCCTGTCC 
ATGTCCCTGA TGGAGCAGCT GCTCAAAACT CTGCGCTACA ACTTCCTGCC TGAGGCCCTG 
GACTTCGTGG GTGTCCACCA GGAGCGGACC TTACAGTGCC TCAACGCAGT GAGGACAGTG 
CAGAGTCTGG CCTGCCTGGA GGAGGCGGAC CACACCGTGG GTTTTATTCT GCAGCTCTCT 
AACTTCATGA AGGAGTGGCA CTTCCACCTG CCTCAGCTCA TGCGTGATAT CCAGGTCAAC 
CTGGGTTACT TGTGCCAGGC ATGTACCTCT CTCCTGCACA GTCGAAAGAT GCTGCAGCAT 
TACTTACAGA ACAAAAATGG GGATGGCCTC CCCTCAGCTG TTGCCCAGCG AGTCCAGAGG 
CCACCGTCTG CTGCTTCTGC TGCCCCCTCC TCCTCAAAGC AGCCCGCTGC TGACACAGAG 
GCATCAGAGC AGCAGGCCTT GCACACAGTC CAGTATGGCC TTCTCAAGAT CCTCAGCAAG 
ACGCTGGCAG CCCTGCGCCA CTTCACCCCA GATGTCTGCC AGATTCTGCT GGATCAGTCC 
CTGGACCTTG CTGAATACAA CTTCCTGTTT GCCCTGAGCT TTACCACTCC CACCTTTGAC 
TCCGAAGTGG CCCCCTCCTT CGGGACCCTT CTGGCCACAG TGAATGTGGC CCTCAACATG 
CTTGGAGAGC TGGACAAGAA AAAGGAGCCC CTCACCCAGG CAGTGGGGCT CAGCACACAG 
GCAGAAGGGA CCAGGACGTT AAAGTCCCTC CTGATGTTTA CCATGGAAAA CTGCTTCTAC 
CTGCTCATCT CTCAGGCGAT GCGGTACCTT AGGGACCCGG CTGTGCACCC CCGGGACAAA 
CAGCGGATGA AGCAGGAGCT CAGCTCTGAG TTGAGCACGC TGCTGTCCAG CCTCTCGCGC 
TACTTCCGCC GGGGAGCCCC CAGCTCCCCT GCCACTGGTG TCCTCCCCTC GCCGCAGGGC 
AAGTCCACCT CTCTCTCCAA AGCCAGCCCT GAGAGTCAGG AGCCTCTGAT CCAGTTGGTG 
CAGGCGTTTG TCCGGCATAT GCAAAGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056169.1
CDS	22..5271
Translation	MAAAAGGPCVRSSRELWTILLGRSALRELSQIEAELNKHWRRLLEGLSYYKPPSPSSAEKVKANKDVASPLKELGLRISKFLGLDEEQSVQLLQCYLQEDYRGTRDSVKTVLQDERQSQALILKIADYYYEERTCILRCVLHLLTYFQDERHPYRVEYADCVDKLEKELVSKYRQQFEELYKTEAPTWETHGNLMTERQVSRWFVQCLREQSMLLEIIFLYYAYFEMAPSDLLVLTKMFKEQGFGSRQTNRHLVDETMDPFVDRIGYFSALILVEGMDIESLHKCALDDRRELHQFAQDGLICQDMDCLMLTFGDIPHHAPVLLAWALLRHTLNPEETSSVVRKIGGTAIQLNVFQYLTRLLQSLASGGNDCTTSTACMCVYGLLSFVLTSLELHTLGNQQDIIDTACEVLADPSLPELFWGTEPTSGLGIILDSVCGMFPHLLSPLLQLLRALVSGKSTAKKVYSFLDKMSFYNELYKHKPHDVISHEDGTLWRRQTPKLLYPLGGQTNLRIPQGTVGQVMLDDRAYLVRWEYSYSSWTLFTCEIEMLLHVVSTADVIQHCQRVKPIIDLVHKVISTDLSIADCLLPITSRIYMLLQRLTTVISPPVDVIASCVNCLTVLAARNPAKVWTDLRHTGFLPFVAHPVSSLSQMISAEGMNAGGYGNLLMNSEQPQGEYGVTIAFLRLITTLVKGQLGSTQSQGLVPCVMFVLKEMLPSYHKWRYNSHGVREQIGCLILELIHAILNLCHETDLHSSHTPSLQFLCICSLAYTEAGQTVINIMGIGVDTIDMVMAAQPRSDGAEGQGQGQLLIKTVKLAFSVTNNVIRLKPPSNVVSPLEQALSQHGAHGNNLIAVLAKYIYHKHDPALPRLAIQLLKRLATVAPMSVYACLGNDAAAIRDAFLTRLQSKIEDMRIKVMILEFLTVAVETQPGLIELFLNLEVKDGSDGSKEFSLGMWSCLHAVLELIDSQQQDRYWCPPLLHRAAIAFLHALWQDRRDSAMLVLRTKPKFWENLTSPLFGTLSPPSETSEPSILETCALIMKIICLEIYYVVKGSLDQSLKDTLKKFSIEKRFAYWSGYVKSLAVHVAETEGSSCTSLLEYQMLVSAWRMLLIIATTHADIMHLTDSVVRRQLFLDVLDGTKALLLVPASVNCLRLGSMKCTLLLILLRQWKRELGSVDEILGPLTEILEGVLQADQQLMEKTKAKVFSAFITVLQMKEMKVSDIPQYSQLVLNVCETLQEEVIALFDQTRHSLALGSATEDKDSMETDDCSRSRHRDQRDGVCVLGLHLAKELCEVDEDGDSWLQVTRRLPILPTLLTTLEVSLRMKQNLHFTEATLHLLLTLARTQQGATAVAGAGITQSICLPLLSVYQLSTNGTAQTPSASRKSLDAPSWPGVYRLSMSLMEQLLKTLRYNFLPEALDFVGVHQERTLQCLNAVRTVQSLACLEEADHTVGFILQLSNFMKEWHFHLPQLMRDIQVNLGYLCQACTSLLHSRKMLQHYLQNKNGDGLPSAVAQRVQRPPSAASAAPSSSKQPAADTEASEQQALHTVQYGLLKILSKTLAALRHFTPDVCQILLDQSLDLAEYNFLFALSFTTPTFDSEVAPSFGTLLATVNVALNMLGELDKKKEPLTQAVGLSTQAEGTRTLKSLLMFTMENCFYLLISQAMRYLRDPAVHPRDKQRMKQELSSELSTLLSSLSRYFRRGAPSSPATGVLPSPQGKSTSLSKASPESQEPLIQLVQAFVRHMQR

Target ORF information:

RefSeq Version	NM_015354.3
Organism	Homo sapiens(human)
Definition	Homo sapiens nucleoporin 188 (NUP188), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015354.3

ORF Insert Sequence:

ATGGCGGCGG CCGCCGGCGG GCCGTGTGTG AGGAGCAGTA GAGAACTGTG GACTATTCTG 
CTTGGAAGGT CAGCTCTGAG AGAGCTGAGT CAGATTGAGG CAGAACTGAA TAAACATTGG 
CGGCGATTGT TAGAGGGGCT TTCTTACTAC AAACCTCCCA GTCCAAGTTC AGCTGAAAAA 
GTGAAAGCTA ATAAAGATGT AGCTTCACCA TTGAAGGAAC TGGGTTTAAG AATCAGCAAG 
TTTTTGGGTC TTGATGAAGA ACAGAGTGTG CAGTTACTCC AGTGTTACCT GCAAGAGGAC 
TACAGGGGTA CTCGGGACTC AGTAAAGACA GTACTGCAAG ATGAGAGGCA GAGCCAGGCC 
TTAATCCTGA AGATTGCAGA TTATTATTAT GAAGAAAGAA CCTGTATTCT TCGTTGTGTC 
TTACACCTTC TCACTTACTT CCAAGATGAA AGACACCCCT ATAGGGTTGA ATATGCAGAC 
TGTGTTGATA AATTGGAGAA GGAACTAGTT TCAAAATACA GACAGCAGTT CGAAGAGCTT 
TATAAAACTG AAGCACCAAC TTGGGAGACA CATGGAAATC TCATGACAGA GCGCCAAGTG 
TCTCGCTGGT TTGTTCAGTG CCTTCGGGAA CAGTCCATGC TGCTAGAAAT TATTTTCCTT 
TATTATGCAT ACTTTGAGAT GGCACCCAGT GACTTACTTG TATTAACCAA GATGTTTAAA 
GAGCAAGGAT TTGGTAGTAG GCAGACCAAT AGGCACCTGG TGGATGAGAC TATGGATCCT 
TTTGTAGATC GGATTGGCTA CTTCAGTGCC CTCATCCTGG TGGAGGGCAT GGATATCGAG 
TCCTTGCATA AGTGTGCTTT GGATGACAGA AGAGAACTGC ATCAGTTTGC GCAGGATGGG 
CTTATTTGTC AGGATATGGA CTGTTTAATG TTGACCTTTG GGGACATTCC ACATCATGCC 
CCAGTGCTTT TGGCCTGGGC TCTCCTCCGT CACACTCTGA ACCCAGAAGA GACAAGCAGT 
GTGGTCCGGA AGATAGGTGG CACAGCCATC CAGCTGAATG TGTTTCAGTA CTTGACCCGA 
TTGCTCCAGT CCCTTGCCAG TGGGGGAAAT GATTGCACCA CCAGCACTGC ATGCATGTGT 
GTCTATGGAC TGCTCTCTTT CGTTCTGACC TCGTTGGAGC TGCACACCCT GGGCAATCAG 
CAGGATATAA TTGATACAGC ATGTGAAGTA TTGGCCGACC CTTCTCTTCC GGAACTGTTC 
TGGGGAACAG AGCCAACTTC TGGCCTTGGG ATCATTCTGG ACAGTGTGTG TGGAATGTTT 
CCCCACCTTC TCTCCCCACT CCTGCAACTG CTCCGAGCCC TGGTATCAGG GAAGTCCACA 
GCCAAAAAGG TGTATAGCTT CTTGGATAAG ATGTCTTTCT ACAATGAACT TTATAAACAC 
AAGCCTCATG ATGTGATCTC CCATGAAGAT GGAACTCTTT GGCGGAGACA AACACCCAAA 
CTCCTTTATC CCCTTGGGGG TCAAACCAAC CTTCGCATAC CTCAAGGCAC TGTGGGCCAA 
GTAATGTTGG ATGATAGGGC ATACCTGGTA CGCTGGGAAT ACTCCTATAG CAGCTGGACC 
CTCTTTACCT GCGAGATTGA AATGTTGCTT CATGTTGTTT CAACTGCAGA TGTGATTCAG 
CACTGCCAGC GAGTCAAACC CATCATTGAT CTCGTCCATA AGGTCATCAG TACAGACCTG 
TCGATAGCAG ACTGTCTCCT GCCCATCACA TCTCGCATCT ACATGCTGCT GCAGCGGTTA 
ACGACAGTGA TCTCCCCACC TGTGGATGTC ATTGCTTCTT GTGTCAACTG CTTAACTGTT 
TTGGCTGCCC GCAATCCAGC AAAGGTCTGG ACTGATCTTC GTCACACAGG TTTTTTACCA 
TTTGTGGCCC ATCCTGTCTC CAGCCTGAGT CAGATGATTA GTGCGGAAGG GATGAATGCT 
GGAGGGTACG GAAACCTCTT GATGAACAGT GAACAGCCTC AGGGCGAGTA TGGGGTTACT 
ATTGCCTTTC TGCGCTTGAT CACCACCCTT GTCAAGGGGC AACTTGGTAG TACCCAGAGC 
CAAGGACTTG TACCCTGTGT AATGTTTGTG CTGAAGGAGA TGCTTCCCAG CTACCATAAG 
TGGCGCTACA ACTCTCATGG AGTGAGGGAA CAGATTGGTT GCCTGATCTT GGAGCTGATT 
CATGCGATAC TGAACCTGTG CCACGAGACA GACCTGCACA GCAGTCATAC TCCCAGCCTG 
CAGTTTCTCT GCATCTGCAG CCTGGCATAC ACAGAAGCAG GACAGACAGT TATCAATATC 
ATGGGCATTG GCGTGGACAC CATTGACATG GTGATGGCTG CTCAGCCTCG AAGTGATGGG 
GCAGAGGGCC AGGGGCAGGG CCAGCTGCTG ATCAAGACAG TGAAACTGGC ATTCTCCGTC 
ACCAACAATG TTATTCGGCT GAAACCTCCT TCTAATGTGG TGTCCCCCCT GGAACAGGCT 
CTCTCACAAC ATGGTGCTCA TGGAAACAAC CTCATTGCTG TTCTAGCCAA ATACATCTAC 
CACAAACATG ACCCTGCTTT GCCACGTCTT GCCATTCAGC TGCTGAAACG TCTGGCCACG 
GTGGCCCCAA TGTCAGTGTA TGCTTGTCTG GGCAATGATG CGGCTGCCAT TCGTGATGCC 
TTCCTGACCC GATTGCAGAG CAAAATTGAG GACATGCGCA TCAAAGTCAT GATTCTAGAG 
TTCCTCACTG TTGCAGTAGA GACCCAGCCA GGCCTCATCG AACTGTTTCT GAACCTGGAA 
GTTAAGGATG GCAGTGATGG CTCAAAGGAA TTCAGCCTTG GGATGTGGAG CTGTCTCCAT 
GCAGTGCTGG AGCTGATTGA TTCCCAACAG CAAGATCGAT ACTGGTGCCC ACCCCTGCTG 
CATCGTGCCG CCATTGCCTT TTTGCATGCT CTGTGGCAGG ATCGGAGGGA CAGTGCCATG 
CTGGTCCTCC GAACCAAACC CAAGTTTTGG GAAAATTTAA CCAGTCCGCT GTTTGGAACC 
CTTTCTCCTC CCTCTGAAAC ATCAGAGCCC AGCATCCTGG AAACCTGTGC CCTAATCATG 
AAGATAATTT GCTTGGAGAT ATACTATGTA GTAAAGGGTT CATTAGACCA GTCATTAAAG 
GATACACTGA AGAAATTTTC CATCGAGAAA CGCTTTGCCT ACTGGTCAGG GTATGTCAAG 
TCATTGGCAG TTCACGTGGC CGAAACAGAA GGCAGCAGCT GCACCTCCTT GTTAGAGTAC 
CAGATGCTGG TGTCCGCCTG GAGGATGCTT CTCATCATTG CCACCACTCA TGCAGATATA 
ATGCACCTGA CTGACTCTGT GGTGCGTCGC CAGCTCTTTC TTGACGTGCT TGATGGAACC 
AAAGCATTAC TCCTAGTTCC AGCCTCAGTG AACTGCCTTC GCCTTGGCTC CATGAAGTGC 
ACTCTGCTGC TTATCCTCCT CCGGCAGTGG AAGAGAGAGT TAGGTTCTGT GGATGAAATC 
CTTGGACCCT TGACGGAGAT CCTGGAGGGA GTGCTGCAGG CCGACCAGCA ACTCATGGAG 
AAGACCAAGG CCAAGGTGTT CTCAGCATTC ATCACAGTGT TGCAAATGAA GGAGATGAAA 
GTAAGTGACA TCCCCCAGTA CTCCCAGCTG GTGCTGAATG TCTGTGAGAC CCTCCAAGAG 
GAAGTGATTG CACTCTTCGA CCAGACCCGC CACAGTCTGG CATTAGGCAG TGCCACAGAG 
GACAAGGACA GCATGGAGAC TGACGACTGT TCTCGGTCCC GGCACAGGGA CCAGCGTGAT 
GGGGTGTGTG TCCTGGGCCT GCACCTGGCC AAGGAGCTGT GTGAGGTAGA CGAGGATGGT 
GACTCCTGGC TGCAGGTAAC CCGCAGGCTC CCCATCCTAC CCACCCTCCT CACCACTCTA 
GAGGTGAGCC TTCGCATGAA GCAGAACCTG CATTTCACTG AGGCCACATT GCATCTGCTC 
CTCACCCTGG CTCGCACTCA GCAGGGAGCC ACAGCAGTGG CTGGAGCTGG CATCACCCAG 
AGCATTTGTT TGCCCCTTCT GAGTGTGTAC CAGCTGAGCA CCAACGGCAC AGCACAGACA 
CCTAGTGCCT CTCGGAAGTC CCTGGATGCC CCCTCTTGGC CAGGAGTCTA CCGCCTGTCC 
ATGTCCCTGA TGGAGCAGCT GCTCAAAACT CTGCGCTACA ACTTCCTGCC TGAGGCCCTG 
GACTTCGTGG GTGTCCACCA GGAGCGGACC TTACAGTGCC TCAACGCAGT GAGGACAGTG 
CAGAGTCTGG CCTGCCTGGA GGAGGCGGAC CACACCGTGG GTTTTATTCT GCAGCTCTCT 
AACTTCATGA AGGAGTGGCA CTTCCACCTG CCTCAGCTCA TGCGTGATAT CCAGGTCAAC 
CTGGGTTACT TGTGCCAGGC ATGTACCTCT CTCCTGCACA GTCGAAAGAT GCTGCAGCAT 
TACTTACAGA ACAAAAATGG GGATGGCCTC CCCTCAGCTG TTGCCCAGCG AGTCCAGAGG 
CCACCGTCTG CTGCTTCTGC TGCCCCCTCC TCCTCAAAGC AGCCCGCTGC TGACACAGAG 
GCATCAGAGC AGCAGGCCTT GCACACAGTC CAGTATGGCC TTCTCAAGAT CCTCAGCAAG 
ACGCTGGCAG CCCTGCGCCA CTTCACCCCA GATGTCTGCC AGATTCTGCT GGATCAGTCC 
CTGGACCTTG CTGAATACAA CTTCCTGTTT GCCCTGAGCT TTACCACTCC CACCTTTGAC 
TCCGAAGTGG CCCCCTCCTT CGGGACCCTT CTGGCCACAG TGAATGTGGC CCTCAACATG 
CTTGGAGAGC TGGACAAGAA AAAGGAGCCC CTCACCCAGG CAGTGGGGCT CAGCACACAG 
GCAGAAGGGA CCAGGACGTT AAAGTCCCTC CTGATGTTTA CCATGGAAAA CTGCTTCTAC 
CTGCTCATCT CTCAGGCGAT GCGGTACCTT AGGGACCCGG CTGTGCACCC CCGGGACAAA 
CAGCGGATGA AGCAGGAGCT CAGCTCTGAG TTGAGCACGC TGCTGTCCAG CCTCTCGCGC 
TACTTCCGCC GGGGAGCCCC CAGCTCCCCT GCCACTGGTG TCCTCCCCTC GCCGCAGGGC 
AAGTCCACCT CTCTCTCCAA AGCCAGCCCT GAGAGTCAGG AGCCTCTGAT CCAGTTGGTG 
CAGGCGTTTG TCCGGCATAT GCAAAGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NUP188 ( NM_015354.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_056169.1 Homo sapiens nucleoporin 188 (NUP188), mRNA.

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CloneID	OHu20110
Clone ID Related Accession (Same CDS sequence)	NM_015354.3 , NM_015354.2
Accession Version	NM_015354.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5250bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	nucleoporin NUP188 homolog
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY094051.1, D79991.1 and AA731883.1. This sequence is a reference standard in the RefSeqGene project. On Jan 25, 2013 this sequence version replaced NM_015354.1. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.225471.1, SRR1660809.113796.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGG CCGCCGGCGG GCCGTGTGTG AGGAGCAGTA GAGAACTGTG GACTATTCTG 
CTTGGAAGGT CAGCTCTGAG AGAGCTGAGT CAGATTGAGG CAGAACTGAA TAAACATTGG 
CGGCGATTGT TAGAGGGGCT TTCTTACTAC AAACCTCCCA GTCCAAGTTC AGCTGAAAAA 
GTGAAAGCTA ATAAAGATGT AGCTTCACCA TTGAAGGAAC TGGGTTTAAG AATCAGCAAG 
TTTTTGGGTC TTGATGAAGA ACAGAGTGTG CAGTTACTCC AGTGTTACCT GCAAGAGGAC 
TACAGGGGTA CTCGGGACTC AGTAAAGACA GTACTGCAAG ATGAGAGGCA GAGCCAGGCC 
TTAATCCTGA AGATTGCAGA TTATTATTAT GAAGAAAGAA CCTGTATTCT TCGTTGTGTC 
TTACACCTTC TCACTTACTT CCAAGATGAA AGACACCCCT ATAGGGTTGA ATATGCAGAC 
TGTGTTGATA AATTGGAGAA GGAACTAGTT TCAAAATACA GACAGCAGTT CGAAGAGCTT 
TATAAAACTG AAGCACCAAC TTGGGAGACA CATGGAAATC TCATGACAGA GCGCCAAGTG 
TCTCGCTGGT TTGTTCAGTG CCTTCGGGAA CAGTCCATGC TGCTAGAAAT TATTTTCCTT 
TATTATGCAT ACTTTGAGAT GGCACCCAGT GACTTACTTG TATTAACCAA GATGTTTAAA 
GAGCAAGGAT TTGGTAGTAG GCAGACCAAT AGGCACCTGG TGGATGAGAC TATGGATCCT 
TTTGTAGATC GGATTGGCTA CTTCAGTGCC CTCATCCTGG TGGAGGGCAT GGATATCGAG 
TCCTTGCATA AGTGTGCTTT GGATGACAGA AGAGAACTGC ATCAGTTTGC GCAGGATGGG 
CTTATTTGTC AGGATATGGA CTGTTTAATG TTGACCTTTG GGGACATTCC ACATCATGCC 
CCAGTGCTTT TGGCCTGGGC TCTCCTCCGT CACACTCTGA ACCCAGAAGA GACAAGCAGT 
GTGGTCCGGA AGATAGGTGG CACAGCCATC CAGCTGAATG TGTTTCAGTA CTTGACCCGA 
TTGCTCCAGT CCCTTGCCAG TGGGGGAAAT GATTGCACCA CCAGCACTGC ATGCATGTGT 
GTCTATGGAC TGCTCTCTTT CGTTCTGACC TCGTTGGAGC TGCACACCCT GGGCAATCAG 
CAGGATATAA TTGATACAGC ATGTGAAGTA TTGGCCGACC CTTCTCTTCC GGAACTGTTC 
TGGGGAACAG AGCCAACTTC TGGCCTTGGG ATCATTCTGG ACAGTGTGTG TGGAATGTTT 
CCCCACCTTC TCTCCCCACT CCTGCAACTG CTCCGAGCCC TGGTATCAGG GAAGTCCACA 
GCCAAAAAGG TGTATAGCTT CTTGGATAAG ATGTCTTTCT ACAATGAACT TTATAAACAC 
AAGCCTCATG ATGTGATCTC CCATGAAGAT GGAACTCTTT GGCGGAGACA AACACCCAAA 
CTCCTTTATC CCCTTGGGGG TCAAACCAAC CTTCGCATAC CTCAAGGCAC TGTGGGCCAA 
GTAATGTTGG ATGATAGGGC ATACCTGGTA CGCTGGGAAT ACTCCTATAG CAGCTGGACC 
CTCTTTACCT GCGAGATTGA AATGTTGCTT CATGTTGTTT CAACTGCAGA TGTGATTCAG 
CACTGCCAGC GAGTCAAACC CATCATTGAT CTCGTCCATA AGGTCATCAG TACAGACCTG 
TCGATAGCAG ACTGTCTCCT GCCCATCACA TCTCGCATCT ACATGCTGCT GCAGCGGTTA 
ACGACAGTGA TCTCCCCACC TGTGGATGTC ATTGCTTCTT GTGTCAACTG CTTAACTGTT 
TTGGCTGCCC GCAATCCAGC AAAGGTCTGG ACTGATCTTC GTCACACAGG TTTTTTACCA 
TTTGTGGCCC ATCCTGTCTC CAGCCTGAGT CAGATGATTA GTGCGGAAGG GATGAATGCT 
GGAGGGTACG GAAACCTCTT GATGAACAGT GAACAGCCTC AGGGCGAGTA TGGGGTTACT 
ATTGCCTTTC TGCGCTTGAT CACCACCCTT GTCAAGGGGC AACTTGGTAG TACCCAGAGC 
CAAGGACTTG TACCCTGTGT AATGTTTGTG CTGAAGGAGA TGCTTCCCAG CTACCATAAG 
TGGCGCTACA ACTCTCATGG AGTGAGGGAA CAGATTGGTT GCCTGATCTT GGAGCTGATT 
CATGCGATAC TGAACCTGTG CCACGAGACA GACCTGCACA GCAGTCATAC TCCCAGCCTG 
CAGTTTCTCT GCATCTGCAG CCTGGCATAC ACAGAAGCAG GACAGACAGT TATCAATATC 
ATGGGCATTG GCGTGGACAC CATTGACATG GTGATGGCTG CTCAGCCTCG AAGTGATGGG 
GCAGAGGGCC AGGGGCAGGG CCAGCTGCTG ATCAAGACAG TGAAACTGGC ATTCTCCGTC 
ACCAACAATG TTATTCGGCT GAAACCTCCT TCTAATGTGG TGTCCCCCCT GGAACAGGCT 
CTCTCACAAC ATGGTGCTCA TGGAAACAAC CTCATTGCTG TTCTAGCCAA ATACATCTAC 
CACAAACATG ACCCTGCTTT GCCACGTCTT GCCATTCAGC TGCTGAAACG TCTGGCCACG 
GTGGCCCCAA TGTCAGTGTA TGCTTGTCTG GGCAATGATG CGGCTGCCAT TCGTGATGCC 
TTCCTGACCC GATTGCAGAG CAAAATTGAG GACATGCGCA TCAAAGTCAT GATTCTAGAG 
TTCCTCACTG TTGCAGTAGA GACCCAGCCA GGCCTCATCG AACTGTTTCT GAACCTGGAA 
GTTAAGGATG GCAGTGATGG CTCAAAGGAA TTCAGCCTTG GGATGTGGAG CTGTCTCCAT 
GCAGTGCTGG AGCTGATTGA TTCCCAACAG CAAGATCGAT ACTGGTGCCC ACCCCTGCTG 
CATCGTGCCG CCATTGCCTT TTTGCATGCT CTGTGGCAGG ATCGGAGGGA CAGTGCCATG 
CTGGTCCTCC GAACCAAACC CAAGTTTTGG GAAAATTTAA CCAGTCCGCT GTTTGGAACC 
CTTTCTCCTC CCTCTGAAAC ATCAGAGCCC AGCATCCTGG AAACCTGTGC CCTAATCATG 
AAGATAATTT GCTTGGAGAT ATACTATGTA GTAAAGGGTT CATTAGACCA GTCATTAAAG 
GATACACTGA AGAAATTTTC CATCGAGAAA CGCTTTGCCT ACTGGTCAGG GTATGTCAAG 
TCATTGGCAG TTCACGTGGC CGAAACAGAA GGCAGCAGCT GCACCTCCTT GTTAGAGTAC 
CAGATGCTGG TGTCCGCCTG GAGGATGCTT CTCATCATTG CCACCACTCA TGCAGATATA 
ATGCACCTGA CTGACTCTGT GGTGCGTCGC CAGCTCTTTC TTGACGTGCT TGATGGAACC 
AAAGCATTAC TCCTAGTTCC AGCCTCAGTG AACTGCCTTC GCCTTGGCTC CATGAAGTGC 
ACTCTGCTGC TTATCCTCCT CCGGCAGTGG AAGAGAGAGT TAGGTTCTGT GGATGAAATC 
CTTGGACCCT TGACGGAGAT CCTGGAGGGA GTGCTGCAGG CCGACCAGCA ACTCATGGAG 
AAGACCAAGG CCAAGGTGTT CTCAGCATTC ATCACAGTGT TGCAAATGAA GGAGATGAAA 
GTAAGTGACA TCCCCCAGTA CTCCCAGCTG GTGCTGAATG TCTGTGAGAC CCTCCAAGAG 
GAAGTGATTG CACTCTTCGA CCAGACCCGC CACAGTCTGG CATTAGGCAG TGCCACAGAG 
GACAAGGACA GCATGGAGAC TGACGACTGT TCTCGGTCCC GGCACAGGGA CCAGCGTGAT 
GGGGTGTGTG TCCTGGGCCT GCACCTGGCC AAGGAGCTGT GTGAGGTAGA CGAGGATGGT 
GACTCCTGGC TGCAGGTAAC CCGCAGGCTC CCCATCCTAC CCACCCTCCT CACCACTCTA 
GAGGTGAGCC TTCGCATGAA GCAGAACCTG CATTTCACTG AGGCCACATT GCATCTGCTC 
CTCACCCTGG CTCGCACTCA GCAGGGAGCC ACAGCAGTGG CTGGAGCTGG CATCACCCAG 
AGCATTTGTT TGCCCCTTCT GAGTGTGTAC CAGCTGAGCA CCAACGGCAC AGCACAGACA 
CCTAGTGCCT CTCGGAAGTC CCTGGATGCC CCCTCTTGGC CAGGAGTCTA CCGCCTGTCC 
ATGTCCCTGA TGGAGCAGCT GCTCAAAACT CTGCGCTACA ACTTCCTGCC TGAGGCCCTG 
GACTTCGTGG GTGTCCACCA GGAGCGGACC TTACAGTGCC TCAACGCAGT GAGGACAGTG 
CAGAGTCTGG CCTGCCTGGA GGAGGCGGAC CACACCGTGG GTTTTATTCT GCAGCTCTCT 
AACTTCATGA AGGAGTGGCA CTTCCACCTG CCTCAGCTCA TGCGTGATAT CCAGGTCAAC 
CTGGGTTACT TGTGCCAGGC ATGTACCTCT CTCCTGCACA GTCGAAAGAT GCTGCAGCAT 
TACTTACAGA ACAAAAATGG GGATGGCCTC CCCTCAGCTG TTGCCCAGCG AGTCCAGAGG 
CCACCGTCTG CTGCTTCTGC TGCCCCCTCC TCCTCAAAGC AGCCCGCTGC TGACACAGAG 
GCATCAGAGC AGCAGGCCTT GCACACAGTC CAGTATGGCC TTCTCAAGAT CCTCAGCAAG 
ACGCTGGCAG CCCTGCGCCA CTTCACCCCA GATGTCTGCC AGATTCTGCT GGATCAGTCC 
CTGGACCTTG CTGAATACAA CTTCCTGTTT GCCCTGAGCT TTACCACTCC CACCTTTGAC 
TCCGAAGTGG CCCCCTCCTT CGGGACCCTT CTGGCCACAG TGAATGTGGC CCTCAACATG 
CTTGGAGAGC TGGACAAGAA AAAGGAGCCC CTCACCCAGG CAGTGGGGCT CAGCACACAG 
GCAGAAGGGA CCAGGACGTT AAAGTCCCTC CTGATGTTTA CCATGGAAAA CTGCTTCTAC 
CTGCTCATCT CTCAGGCGAT GCGGTACCTT AGGGACCCGG CTGTGCACCC CCGGGACAAA 
CAGCGGATGA AGCAGGAGCT CAGCTCTGAG TTGAGCACGC TGCTGTCCAG CCTCTCGCGC 
TACTTCCGCC GGGGAGCCCC CAGCTCCCCT GCCACTGGTG TCCTCCCCTC GCCGCAGGGC 
AAGTCCACCT CTCTCTCCAA AGCCAGCCCT GAGAGTCAGG AGCCTCTGAT CCAGTTGGTG 
CAGGCGTTTG TCCGGCATAT GCAAAGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056169.1
CDS	28..5277
Translation	MAAAAGGPCVRSSRELWTILLGRSALRELSQIEAELNKHWRRLLEGLSYYKPPSPSSAEKVKANKDVASPLKELGLRISKFLGLDEEQSVQLLQCYLQEDYRGTRDSVKTVLQDERQSQALILKIADYYYEERTCILRCVLHLLTYFQDERHPYRVEYADCVDKLEKELVSKYRQQFEELYKTEAPTWETHGNLMTERQVSRWFVQCLREQSMLLEIIFLYYAYFEMAPSDLLVLTKMFKEQGFGSRQTNRHLVDETMDPFVDRIGYFSALILVEGMDIESLHKCALDDRRELHQFAQDGLICQDMDCLMLTFGDIPHHAPVLLAWALLRHTLNPEETSSVVRKIGGTAIQLNVFQYLTRLLQSLASGGNDCTTSTACMCVYGLLSFVLTSLELHTLGNQQDIIDTACEVLADPSLPELFWGTEPTSGLGIILDSVCGMFPHLLSPLLQLLRALVSGKSTAKKVYSFLDKMSFYNELYKHKPHDVISHEDGTLWRRQTPKLLYPLGGQTNLRIPQGTVGQVMLDDRAYLVRWEYSYSSWTLFTCEIEMLLHVVSTADVIQHCQRVKPIIDLVHKVISTDLSIADCLLPITSRIYMLLQRLTTVISPPVDVIASCVNCLTVLAARNPAKVWTDLRHTGFLPFVAHPVSSLSQMISAEGMNAGGYGNLLMNSEQPQGEYGVTIAFLRLITTLVKGQLGSTQSQGLVPCVMFVLKEMLPSYHKWRYNSHGVREQIGCLILELIHAILNLCHETDLHSSHTPSLQFLCICSLAYTEAGQTVINIMGIGVDTIDMVMAAQPRSDGAEGQGQGQLLIKTVKLAFSVTNNVIRLKPPSNVVSPLEQALSQHGAHGNNLIAVLAKYIYHKHDPALPRLAIQLLKRLATVAPMSVYACLGNDAAAIRDAFLTRLQSKIEDMRIKVMILEFLTVAVETQPGLIELFLNLEVKDGSDGSKEFSLGMWSCLHAVLELIDSQQQDRYWCPPLLHRAAIAFLHALWQDRRDSAMLVLRTKPKFWENLTSPLFGTLSPPSETSEPSILETCALIMKIICLEIYYVVKGSLDQSLKDTLKKFSIEKRFAYWSGYVKSLAVHVAETEGSSCTSLLEYQMLVSAWRMLLIIATTHADIMHLTDSVVRRQLFLDVLDGTKALLLVPASVNCLRLGSMKCTLLLILLRQWKRELGSVDEILGPLTEILEGVLQADQQLMEKTKAKVFSAFITVLQMKEMKVSDIPQYSQLVLNVCETLQEEVIALFDQTRHSLALGSATEDKDSMETDDCSRSRHRDQRDGVCVLGLHLAKELCEVDEDGDSWLQVTRRLPILPTLLTTLEVSLRMKQNLHFTEATLHLLLTLARTQQGATAVAGAGITQSICLPLLSVYQLSTNGTAQTPSASRKSLDAPSWPGVYRLSMSLMEQLLKTLRYNFLPEALDFVGVHQERTLQCLNAVRTVQSLACLEEADHTVGFILQLSNFMKEWHFHLPQLMRDIQVNLGYLCQACTSLLHSRKMLQHYLQNKNGDGLPSAVAQRVQRPPSAASAAPSSSKQPAADTEASEQQALHTVQYGLLKILSKTLAALRHFTPDVCQILLDQSLDLAEYNFLFALSFTTPTFDSEVAPSFGTLLATVNVALNMLGELDKKKEPLTQAVGLSTQAEGTRTLKSLLMFTMENCFYLLISQAMRYLRDPAVHPRDKQRMKQELSSELSTLLSSLSRYFRRGAPSSPATGVLPSPQGKSTSLSKASPESQEPLIQLVQAFVRHMQR

Target ORF information:

RefSeq Version	NM_015354.2
Organism	Homo sapiens(human)
Definition	Homo sapiens nucleoporin 188 (NUP188), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015354.2

ORF Insert Sequence:

ATGGCGGCGG CCGCCGGCGG GCCGTGTGTG AGGAGCAGTA GAGAACTGTG GACTATTCTG 
CTTGGAAGGT CAGCTCTGAG AGAGCTGAGT CAGATTGAGG CAGAACTGAA TAAACATTGG 
CGGCGATTGT TAGAGGGGCT TTCTTACTAC AAACCTCCCA GTCCAAGTTC AGCTGAAAAA 
GTGAAAGCTA ATAAAGATGT AGCTTCACCA TTGAAGGAAC TGGGTTTAAG AATCAGCAAG 
TTTTTGGGTC TTGATGAAGA ACAGAGTGTG CAGTTACTCC AGTGTTACCT GCAAGAGGAC 
TACAGGGGTA CTCGGGACTC AGTAAAGACA GTACTGCAAG ATGAGAGGCA GAGCCAGGCC 
TTAATCCTGA AGATTGCAGA TTATTATTAT GAAGAAAGAA CCTGTATTCT TCGTTGTGTC 
TTACACCTTC TCACTTACTT CCAAGATGAA AGACACCCCT ATAGGGTTGA ATATGCAGAC 
TGTGTTGATA AATTGGAGAA GGAACTAGTT TCAAAATACA GACAGCAGTT CGAAGAGCTT 
TATAAAACTG AAGCACCAAC TTGGGAGACA CATGGAAATC TCATGACAGA GCGCCAAGTG 
TCTCGCTGGT TTGTTCAGTG CCTTCGGGAA CAGTCCATGC TGCTAGAAAT TATTTTCCTT 
TATTATGCAT ACTTTGAGAT GGCACCCAGT GACTTACTTG TATTAACCAA GATGTTTAAA 
GAGCAAGGAT TTGGTAGTAG GCAGACCAAT AGGCACCTGG TGGATGAGAC TATGGATCCT 
TTTGTAGATC GGATTGGCTA CTTCAGTGCC CTCATCCTGG TGGAGGGCAT GGATATCGAG 
TCCTTGCATA AGTGTGCTTT GGATGACAGA AGAGAACTGC ATCAGTTTGC GCAGGATGGG 
CTTATTTGTC AGGATATGGA CTGTTTAATG TTGACCTTTG GGGACATTCC ACATCATGCC 
CCAGTGCTTT TGGCCTGGGC TCTCCTCCGT CACACTCTGA ACCCAGAAGA GACAAGCAGT 
GTGGTCCGGA AGATAGGTGG CACAGCCATC CAGCTGAATG TGTTTCAGTA CTTGACCCGA 
TTGCTCCAGT CCCTTGCCAG TGGGGGAAAT GATTGCACCA CCAGCACTGC ATGCATGTGT 
GTCTATGGAC TGCTCTCTTT CGTTCTGACC TCGTTGGAGC TGCACACCCT GGGCAATCAG 
CAGGATATAA TTGATACAGC ATGTGAAGTA TTGGCCGACC CTTCTCTTCC GGAACTGTTC 
TGGGGAACAG AGCCAACTTC TGGCCTTGGG ATCATTCTGG ACAGTGTGTG TGGAATGTTT 
CCCCACCTTC TCTCCCCACT CCTGCAACTG CTCCGAGCCC TGGTATCAGG GAAGTCCACA 
GCCAAAAAGG TGTATAGCTT CTTGGATAAG ATGTCTTTCT ACAATGAACT TTATAAACAC 
AAGCCTCATG ATGTGATCTC CCATGAAGAT GGAACTCTTT GGCGGAGACA AACACCCAAA 
CTCCTTTATC CCCTTGGGGG TCAAACCAAC CTTCGCATAC CTCAAGGCAC TGTGGGCCAA 
GTAATGTTGG ATGATAGGGC ATACCTGGTA CGCTGGGAAT ACTCCTATAG CAGCTGGACC 
CTCTTTACCT GCGAGATTGA AATGTTGCTT CATGTTGTTT CAACTGCAGA TGTGATTCAG 
CACTGCCAGC GAGTCAAACC CATCATTGAT CTCGTCCATA AGGTCATCAG TACAGACCTG 
TCGATAGCAG ACTGTCTCCT GCCCATCACA TCTCGCATCT ACATGCTGCT GCAGCGGTTA 
ACGACAGTGA TCTCCCCACC TGTGGATGTC ATTGCTTCTT GTGTCAACTG CTTAACTGTT 
TTGGCTGCCC GCAATCCAGC AAAGGTCTGG ACTGATCTTC GTCACACAGG TTTTTTACCA 
TTTGTGGCCC ATCCTGTCTC CAGCCTGAGT CAGATGATTA GTGCGGAAGG GATGAATGCT 
GGAGGGTACG GAAACCTCTT GATGAACAGT GAACAGCCTC AGGGCGAGTA TGGGGTTACT 
ATTGCCTTTC TGCGCTTGAT CACCACCCTT GTCAAGGGGC AACTTGGTAG TACCCAGAGC 
CAAGGACTTG TACCCTGTGT AATGTTTGTG CTGAAGGAGA TGCTTCCCAG CTACCATAAG 
TGGCGCTACA ACTCTCATGG AGTGAGGGAA CAGATTGGTT GCCTGATCTT GGAGCTGATT 
CATGCGATAC TGAACCTGTG CCACGAGACA GACCTGCACA GCAGTCATAC TCCCAGCCTG 
CAGTTTCTCT GCATCTGCAG CCTGGCATAC ACAGAAGCAG GACAGACAGT TATCAATATC 
ATGGGCATTG GCGTGGACAC CATTGACATG GTGATGGCTG CTCAGCCTCG AAGTGATGGG 
GCAGAGGGCC AGGGGCAGGG CCAGCTGCTG ATCAAGACAG TGAAACTGGC ATTCTCCGTC 
ACCAACAATG TTATTCGGCT GAAACCTCCT TCTAATGTGG TGTCCCCCCT GGAACAGGCT 
CTCTCACAAC ATGGTGCTCA TGGAAACAAC CTCATTGCTG TTCTAGCCAA ATACATCTAC 
CACAAACATG ACCCTGCTTT GCCACGTCTT GCCATTCAGC TGCTGAAACG TCTGGCCACG 
GTGGCCCCAA TGTCAGTGTA TGCTTGTCTG GGCAATGATG CGGCTGCCAT TCGTGATGCC 
TTCCTGACCC GATTGCAGAG CAAAATTGAG GACATGCGCA TCAAAGTCAT GATTCTAGAG 
TTCCTCACTG TTGCAGTAGA GACCCAGCCA GGCCTCATCG AACTGTTTCT GAACCTGGAA 
GTTAAGGATG GCAGTGATGG CTCAAAGGAA TTCAGCCTTG GGATGTGGAG CTGTCTCCAT 
GCAGTGCTGG AGCTGATTGA TTCCCAACAG CAAGATCGAT ACTGGTGCCC ACCCCTGCTG 
CATCGTGCCG CCATTGCCTT TTTGCATGCT CTGTGGCAGG ATCGGAGGGA CAGTGCCATG 
CTGGTCCTCC GAACCAAACC CAAGTTTTGG GAAAATTTAA CCAGTCCGCT GTTTGGAACC 
CTTTCTCCTC CCTCTGAAAC ATCAGAGCCC AGCATCCTGG AAACCTGTGC CCTAATCATG 
AAGATAATTT GCTTGGAGAT ATACTATGTA GTAAAGGGTT CATTAGACCA GTCATTAAAG 
GATACACTGA AGAAATTTTC CATCGAGAAA CGCTTTGCCT ACTGGTCAGG GTATGTCAAG 
TCATTGGCAG TTCACGTGGC CGAAACAGAA GGCAGCAGCT GCACCTCCTT GTTAGAGTAC 
CAGATGCTGG TGTCCGCCTG GAGGATGCTT CTCATCATTG CCACCACTCA TGCAGATATA 
ATGCACCTGA CTGACTCTGT GGTGCGTCGC CAGCTCTTTC TTGACGTGCT TGATGGAACC 
AAAGCATTAC TCCTAGTTCC AGCCTCAGTG AACTGCCTTC GCCTTGGCTC CATGAAGTGC 
ACTCTGCTGC TTATCCTCCT CCGGCAGTGG AAGAGAGAGT TAGGTTCTGT GGATGAAATC 
CTTGGACCCT TGACGGAGAT CCTGGAGGGA GTGCTGCAGG CCGACCAGCA ACTCATGGAG 
AAGACCAAGG CCAAGGTGTT CTCAGCATTC ATCACAGTGT TGCAAATGAA GGAGATGAAA 
GTAAGTGACA TCCCCCAGTA CTCCCAGCTG GTGCTGAATG TCTGTGAGAC CCTCCAAGAG 
GAAGTGATTG CACTCTTCGA CCAGACCCGC CACAGTCTGG CATTAGGCAG TGCCACAGAG 
GACAAGGACA GCATGGAGAC TGACGACTGT TCTCGGTCCC GGCACAGGGA CCAGCGTGAT 
GGGGTGTGTG TCCTGGGCCT GCACCTGGCC AAGGAGCTGT GTGAGGTAGA CGAGGATGGT 
GACTCCTGGC TGCAGGTAAC CCGCAGGCTC CCCATCCTAC CCACCCTCCT CACCACTCTA 
GAGGTGAGCC TTCGCATGAA GCAGAACCTG CATTTCACTG AGGCCACATT GCATCTGCTC 
CTCACCCTGG CTCGCACTCA GCAGGGAGCC ACAGCAGTGG CTGGAGCTGG CATCACCCAG 
AGCATTTGTT TGCCCCTTCT GAGTGTGTAC CAGCTGAGCA CCAACGGCAC AGCACAGACA 
CCTAGTGCCT CTCGGAAGTC CCTGGATGCC CCCTCTTGGC CAGGAGTCTA CCGCCTGTCC 
ATGTCCCTGA TGGAGCAGCT GCTCAAAACT CTGCGCTACA ACTTCCTGCC TGAGGCCCTG 
GACTTCGTGG GTGTCCACCA GGAGCGGACC TTACAGTGCC TCAACGCAGT GAGGACAGTG 
CAGAGTCTGG CCTGCCTGGA GGAGGCGGAC CACACCGTGG GTTTTATTCT GCAGCTCTCT 
AACTTCATGA AGGAGTGGCA CTTCCACCTG CCTCAGCTCA TGCGTGATAT CCAGGTCAAC 
CTGGGTTACT TGTGCCAGGC ATGTACCTCT CTCCTGCACA GTCGAAAGAT GCTGCAGCAT 
TACTTACAGA ACAAAAATGG GGATGGCCTC CCCTCAGCTG TTGCCCAGCG AGTCCAGAGG 
CCACCGTCTG CTGCTTCTGC TGCCCCCTCC TCCTCAAAGC AGCCCGCTGC TGACACAGAG 
GCATCAGAGC AGCAGGCCTT GCACACAGTC CAGTATGGCC TTCTCAAGAT CCTCAGCAAG 
ACGCTGGCAG CCCTGCGCCA CTTCACCCCA GATGTCTGCC AGATTCTGCT GGATCAGTCC 
CTGGACCTTG CTGAATACAA CTTCCTGTTT GCCCTGAGCT TTACCACTCC CACCTTTGAC 
TCCGAAGTGG CCCCCTCCTT CGGGACCCTT CTGGCCACAG TGAATGTGGC CCTCAACATG 
CTTGGAGAGC TGGACAAGAA AAAGGAGCCC CTCACCCAGG CAGTGGGGCT CAGCACACAG 
GCAGAAGGGA CCAGGACGTT AAAGTCCCTC CTGATGTTTA CCATGGAAAA CTGCTTCTAC 
CTGCTCATCT CTCAGGCGAT GCGGTACCTT AGGGACCCGG CTGTGCACCC CCGGGACAAA 
CAGCGGATGA AGCAGGAGCT CAGCTCTGAG TTGAGCACGC TGCTGTCCAG CCTCTCGCGC 
TACTTCCGCC GGGGAGCCCC CAGCTCCCCT GCCACTGGTG TCCTCCCCTC GCCGCAGGGC 
AAGTCCACCT CTCTCTCCAA AGCCAGCCCT GAGAGTCAGG AGCCTCTGAT CCAGTTGGTG 
CAGGCGTTTG TCCGGCATAT GCAAAGATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Congenital Heart Disease Genetics Uncovers Context-Dependent Organization and Function of Nucleoporins at Cilia.
Developmental cell38(5)478-92(2016 09)
Del Viso F,Huang F,Myers J,Chalfant M,Zhang Y,Reza N,Bewersdorf J,Lusk CP,Khokha MK

Mutations in nuclear pore genes NUP93, NUP205 and XPO5 cause steroid-resistant nephrotic syndrome.
Nature genetics48(4)457-65(2016 Apr)
Braun DA,Sadowski CE,Kohl S,Lovric S,Astrinidis SA,Pabst WL,Gee HY,Ashraf S,Lawson JA,Shril S,Airik M,Tan W,Schapiro D,Rao J,Choi WI,Hermle T,Kemper MJ,Pohl M,Ozaltin F,Konrad M,Bogdanovic R,B?scher R,Helmchen U,Serdaroglu E,Lifton RP,Antonin W,Hildebrandt F

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA

Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions.
Genome research17(6)746-59(2007 Jun)
Denoeud F,Kapranov P,Ucla C,Frankish A,Castelo R,Drenkow J,Lagarde J,Alioto T,Manzano C,Chrast J,Dike S,Wyss C,Henrichsen CN,Holroyd N,Dickson MC,Taylor R,Hance Z,Foissac S,Myers RM,Rogers J,Hubbard T,Harrow J,Guig? R,Gingeras TR,Antonarakis SE,Reymond A

Identification of a new vertebrate nucleoporin, Nup188, with the use of a novel organelle trap assay.
Molecular biology of the cell11(10)3381-96(2000 Oct)
Miller BR,Powers M,Park M,Fischer W,Forbes DJ

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NUP188 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

ORF Insert Sequence:

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ORF Insert Sequence:

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