ANGPTL2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ANGPTL2
Entrez Gene ID	23452
Full Name	angiopoietin like 2
Synonyms	ARP2,HARP
General protein information	Preferred Names angiopoietin like 2 Names angiopoietin-related protein 2 angiopoietin-like protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9q33.3
Summary	Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action. [provided by RefSeq, Jul 2008].
Disorder MIM:	605001

mRNA and Protein(s)

mRNA	Protein	Name
XM_006717030.3	XP_006717093.1	angiopoietin-related protein 2 isoform X1
NM_012098.3	NP_036230.1	angiopoietin-related protein 2 precursor
NM_012098.2	NP_036230.1	angiopoietin-related protein 2 precursor
XM_006717030.4	XP_006717093.1	angiopoietin-related protein 2 isoform X1

Pathways from BioSystems

Homologies

	ANGPTL2	NP_001103281.1
Xenopus tropicalis (tropical clawed frog)	angptl2	NP_001090872.1
Danio rerio (zebrafish)	angptl2b	NP_001119950.1
Rattus norvegicus (Norway rat)	Angptl2	NP_598253.1
Homo sapiens (human)	ANGPTL2	NP_036230.1
Bos taurus (cattle)	ANGPTL2	NP_001103284.1
Gallus gallus (chicken)	ANGPTL2	NP_001264628.1
Pan troglodytes (chimpanzee)	ANGPTL2	XP_520266.2
Canis lupus familiaris (dog)	ANGPTL2	XP_537840.2
Mus musculus (house mouse)	Angptl2	NP_036053.2
Danio rerio (zebrafish)	angptl2a	NP_001025401.1

Gene Ontology
Bibliography

Related articles in PubMed

Angiopoietin-like protein as a novel marker for liver fibrosis in chronic hepatitis B patients with normal to minimally raised ALT.
Deng Y, Zhao H, Zhou J, Yan L, Wang G,
BMC infectious diseases17(1)650(2017 Sep)

High Circulating Levels of ANGPTL2: Beyond a Clinical Marker of Systemic Inflammation.
Thorin-Trescases N, Thorin E
Oxidative medicine and cellular longevity20171096385(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results reveal a novel cascade comprising sequential P. gingivalis lipopolysaccharide --> ANGPTL2 --> integrin alpha5beta1 --> inflammatory cytokine induction, which might be responsible for inducing potent periodontal disorganization activity in gingival epithelial cells. Via this pathway, ANGPTL2 functions in the pathogenesis of periodontitis and contributes to prolonging chronic inflammation in patients with systemi...
Title: Angiopoietin-like protein 2 regulates Porphyromonas gingivalis lipopolysaccharide-induced inflammatory response in human gingival epithelial cells.

Serum ANGPTL2 levels were significantly increased in non-small cell lung carcinoma patients, which could serve as a novel potential diagnostic and prognostic biomarker for NSCLC.
Title: Diagnostic and Prognostic Value of Serum Angiopoietin-Like Protein 2 in Patients with Non-Small Cell Lung Cancer.

Increased ANGPTL2 expression contributes to proliferation and invasion of gastric cancer cells.

In patients with type 2 diabetes, serum ANGPTL2 concentrations were independently associated with death and MACE.
Title: ANGPTL2 is associated with an increased risk of cardiovascular events and death in diabetic patients.

At 11-13 weeks in pregnancies that develop GDM, the serum concentration of ANGPTL2 is increased, and it can be combined with maternal factors to provide effective early screening for GDM.
Title: Association between Maternal Serum Concentrations of Angiopoietin-like Protein 2 in Early Pregnancy and Subsequent Risk of Gestational Diabetes Mellitus.

The following ANGPTL2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ANGPTL2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27164	NM_012098.3 Latest version!	Homo sapiens angiopoietin like 2 (ANGPTL2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu43141	XM_006717030.4 Latest version!	Homo sapiens angiopoietin like 2 (ANGPTL2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
View Old Accession Versions >>
OHu27164	NM_012098.2	Homo sapiens angiopoietin like 2 (ANGPTL2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu43141	XM_006717030.3	Homo sapiens angiopoietin like 2 (ANGPTL2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ANGPTL2 ( NM_012098.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_036230.1 Homo sapiens angiopoietin like 2 (ANGPTL2), mRNA.

Price & Availability↑

CloneID	OHu27164
Clone ID Related Accession (Same CDS sequence)	NM_012098.3 , NM_012098.2
Accession Version	NM_012098.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1482bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	angiopoietin-related protein 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL598400.1, BC012368.1, AK074726.1 and AL356862.10. On Nov 22, 2018 this sequence version replaced NM_012098.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.944677.1, SRR3476690.517902.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA2142670 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000373425.8/ ENSP00000362524.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGGCCAC TGTGCGTGAC ATGCTGGTGG CTCGGACTGC TGGCTGCCAT GGGAGCTGTT 
GCAGGCCAGG AGGACGGTTT TGAGGGCACT GAGGAGGGCT CGCCAAGAGA GTTCATTTAC 
CTAAACAGGT ACAAGCGGGC GGGCGAGTCC CAGGACAAGT GCACCTACAC CTTCATTGTG 
CCCCAGCAGC GGGTCACGGG TGCCATCTGC GTCAACTCCA AGGAGCCTGA GGTGCTTCTG 
GAGAACCGAG TGCATAAGCA GGAGCTAGAG CTGCTCAACA ATGAGCTGCT CAAGCAGAAG 
CGGCAGATCG AGACGCTGCA GCAGCTGGTG GAGGTGGACG GCGGCATTGT GAGCGAGGTG 
AAGCTGCTGC GCAAGGAGAG CCGCAACATG AACTCGCGGG TCACGCAGCT CTACATGCAG 
CTCCTGCACG AGATCATCCG CAAGCGGGAC AACGCGTTGG AGCTCTCCCA GCTGGAGAAC 
AGGATCCTGA ACCAGACAGC CGACATGCTG CAGCTGGCCA GCAAGTACAA GGACCTGGAG 
CACAAGTACC AGCACCTGGC CACACTGGCC CACAACCAAT CAGAGATCAT CGCGCAGCTT 
GAGGAGCACT GCCAGAGGGT GCCCTCGGCC AGGCCCGTCC CCCAGCCACC CCCCGCTGCC 
CCGCCCCGGG TCTACCAACC ACCCACCTAC AACCGCATCA TCAACCAGAT CTCTACCAAC 
GAGATCCAGA GTGACCAGAA CCTGAAGGTG CTGCCACCCC CTCTGCCCAC TATGCCCACT 
CTCACCAGCC TCCCATCTTC CACCGACAAG CCGTCGGGCC CATGGAGAGA CTGCCTGCAG 
GCCCTGGAGG ATGGCCACGA CACCAGCTCC ATCTACCTGG TGAAGCCGGA GAACACCAAC 
CGCCTCATGC AGGTGTGGTG CGACCAGAGA CACGACCCCG GGGGCTGGAC CGTCATCCAG 
AGACGCCTGG ATGGCTCTGT TAACTTCTTC AGGAACTGGG AGACGTACAA GCAAGGGTTT 
GGGAACATTG ACGGCGAATA CTGGCTGGGC CTGGAGAACA TTTACTGGCT GACGAACCAA 
GGCAACTACA AACTCCTGGT GACCATGGAG GACTGGTCCG GCCGCAAAGT CTTTGCAGAA 
TACGCCAGTT TCCGCCTGGA ACCTGAGAGC GAGTATTATA AGCTGCGGCT GGGGCGCTAC 
CATGGCAATG CGGGTGACTC CTTTACATGG CACAACGGCA AGCAGTTCAC CACCCTGGAC 
AGAGATCATG ATGTCTACAC AGGAAACTGT GCCCACTACC AGAAGGGAGG CTGGTGGTAT 
AACGCCTGTG CCCACTCCAA CCTCAACGGG GTCTGGTACC GCGGGGGCCA TTACCGGAGC 
CGCTACCAGG ACGGAGTCTA CTGGGCTGAG TTCCGAGGAG GCTCTTACTC ACTCAAGAAA 
GTGGTGATGA TGATCCGACC GAACCCCAAC ACCTTCCACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036230.1
CDS	371..1852
Translation	MRPLCVTCWWLGLLAAMGAVAGQEDGFEGTEEGSPREFIYLNRYKRAGESQDKCTYTFIVPQQRVTGAICVNSKEPEVLLENRVHKQELELLNNELLKQKRQIETLQQLVEVDGGIVSEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALELSQLENRILNQTADMLQLASKYKDLEHKYQHLATLAHNQSEIIAQLEEHCQRVPSARPVPQPPPAAPPRVYQPPTYNRIINQISTNEIQSDQNLKVLPPPLPTMPTLTSLPSSTDKPSGPWRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESEYYKLRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRPNPNTFH

Target ORF information:

RefSeq Version	NM_012098.3
Organism	Homo sapiens(human)
Definition	Homo sapiens angiopoietin like 2 (ANGPTL2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012098.3

ORF Insert Sequence:

ATGAGGCCAC TGTGCGTGAC ATGCTGGTGG CTCGGACTGC TGGCTGCCAT GGGAGCTGTT 
GCAGGCCAGG AGGACGGTTT TGAGGGCACT GAGGAGGGCT CGCCAAGAGA GTTCATTTAC 
CTAAACAGGT ACAAGCGGGC GGGCGAGTCC CAGGACAAGT GCACCTACAC CTTCATTGTG 
CCCCAGCAGC GGGTCACGGG TGCCATCTGC GTCAACTCCA AGGAGCCTGA GGTGCTTCTG 
GAGAACCGAG TGCATAAGCA GGAGCTAGAG CTGCTCAACA ATGAGCTGCT CAAGCAGAAG 
CGGCAGATCG AGACGCTGCA GCAGCTGGTG GAGGTGGACG GCGGCATTGT GAGCGAGGTG 
AAGCTGCTGC GCAAGGAGAG CCGCAACATG AACTCGCGGG TCACGCAGCT CTACATGCAG 
CTCCTGCACG AGATCATCCG CAAGCGGGAC AACGCGTTGG AGCTCTCCCA GCTGGAGAAC 
AGGATCCTGA ACCAGACAGC CGACATGCTG CAGCTGGCCA GCAAGTACAA GGACCTGGAG 
CACAAGTACC AGCACCTGGC CACACTGGCC CACAACCAAT CAGAGATCAT CGCGCAGCTT 
GAGGAGCACT GCCAGAGGGT GCCCTCGGCC AGGCCCGTCC CCCAGCCACC CCCCGCTGCC 
CCGCCCCGGG TCTACCAACC ACCCACCTAC AACCGCATCA TCAACCAGAT CTCTACCAAC 
GAGATCCAGA GTGACCAGAA CCTGAAGGTG CTGCCACCCC CTCTGCCCAC TATGCCCACT 
CTCACCAGCC TCCCATCTTC CACCGACAAG CCGTCGGGCC CATGGAGAGA CTGCCTGCAG 
GCCCTGGAGG ATGGCCACGA CACCAGCTCC ATCTACCTGG TGAAGCCGGA GAACACCAAC 
CGCCTCATGC AGGTGTGGTG CGACCAGAGA CACGACCCCG GGGGCTGGAC CGTCATCCAG 
AGACGCCTGG ATGGCTCTGT TAACTTCTTC AGGAACTGGG AGACGTACAA GCAAGGGTTT 
GGGAACATTG ACGGCGAATA CTGGCTGGGC CTGGAGAACA TTTACTGGCT GACGAACCAA 
GGCAACTACA AACTCCTGGT GACCATGGAG GACTGGTCCG GCCGCAAAGT CTTTGCAGAA 
TACGCCAGTT TCCGCCTGGA ACCTGAGAGC GAGTATTATA AGCTGCGGCT GGGGCGCTAC 
CATGGCAATG CGGGTGACTC CTTTACATGG CACAACGGCA AGCAGTTCAC CACCCTGGAC 
AGAGATCATG ATGTCTACAC AGGAAACTGT GCCCACTACC AGAAGGGAGG CTGGTGGTAT 
AACGCCTGTG CCCACTCCAA CCTCAACGGG GTCTGGTACC GCGGGGGCCA TTACCGGAGC 
CGCTACCAGG ACGGAGTCTA CTGGGCTGAG TTCCGAGGAG GCTCTTACTC ACTCAAGAAA 
GTGGTGATGA TGATCCGACC GAACCCCAAC ACCTTCCACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ANGPTL2 ( NM_012098.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_036230.1 Homo sapiens angiopoietin like 2 (ANGPTL2), mRNA.

Price & Availability↑

CloneID	OHu27164
Clone ID Related Accession (Same CDS sequence)	NM_012098.3 , NM_012098.2
Accession Version	NM_012098.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1482bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	angiopoietin-related protein 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL598400.1, BC012368.1 and AK074726.1. On Sep 11, 2003 this sequence version replaced NM_012098.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY358274.1, BC012368.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END##

ATGAGGCCAC TGTGCGTGAC ATGCTGGTGG CTCGGACTGC TGGCTGCCAT GGGAGCTGTT 
GCAGGCCAGG AGGACGGTTT TGAGGGCACT GAGGAGGGCT CGCCAAGAGA GTTCATTTAC 
CTAAACAGGT ACAAGCGGGC GGGCGAGTCC CAGGACAAGT GCACCTACAC CTTCATTGTG 
CCCCAGCAGC GGGTCACGGG TGCCATCTGC GTCAACTCCA AGGAGCCTGA GGTGCTTCTG 
GAGAACCGAG TGCATAAGCA GGAGCTAGAG CTGCTCAACA ATGAGCTGCT CAAGCAGAAG 
CGGCAGATCG AGACGCTGCA GCAGCTGGTG GAGGTGGACG GCGGCATTGT GAGCGAGGTG 
AAGCTGCTGC GCAAGGAGAG CCGCAACATG AACTCGCGGG TCACGCAGCT CTACATGCAG 
CTCCTGCACG AGATCATCCG CAAGCGGGAC AACGCGTTGG AGCTCTCCCA GCTGGAGAAC 
AGGATCCTGA ACCAGACAGC CGACATGCTG CAGCTGGCCA GCAAGTACAA GGACCTGGAG 
CACAAGTACC AGCACCTGGC CACACTGGCC CACAACCAAT CAGAGATCAT CGCGCAGCTT 
GAGGAGCACT GCCAGAGGGT GCCCTCGGCC AGGCCCGTCC CCCAGCCACC CCCCGCTGCC 
CCGCCCCGGG TCTACCAACC ACCCACCTAC AACCGCATCA TCAACCAGAT CTCTACCAAC 
GAGATCCAGA GTGACCAGAA CCTGAAGGTG CTGCCACCCC CTCTGCCCAC TATGCCCACT 
CTCACCAGCC TCCCATCTTC CACCGACAAG CCGTCGGGCC CATGGAGAGA CTGCCTGCAG 
GCCCTGGAGG ATGGCCACGA CACCAGCTCC ATCTACCTGG TGAAGCCGGA GAACACCAAC 
CGCCTCATGC AGGTGTGGTG CGACCAGAGA CACGACCCCG GGGGCTGGAC CGTCATCCAG 
AGACGCCTGG ATGGCTCTGT TAACTTCTTC AGGAACTGGG AGACGTACAA GCAAGGGTTT 
GGGAACATTG ACGGCGAATA CTGGCTGGGC CTGGAGAACA TTTACTGGCT GACGAACCAA 
GGCAACTACA AACTCCTGGT GACCATGGAG GACTGGTCCG GCCGCAAAGT CTTTGCAGAA 
TACGCCAGTT TCCGCCTGGA ACCTGAGAGC GAGTATTATA AGCTGCGGCT GGGGCGCTAC 
CATGGCAATG CGGGTGACTC CTTTACATGG CACAACGGCA AGCAGTTCAC CACCCTGGAC 
AGAGATCATG ATGTCTACAC AGGAAACTGT GCCCACTACC AGAAGGGAGG CTGGTGGTAT 
AACGCCTGTG CCCACTCCAA CCTCAACGGG GTCTGGTACC GCGGGGGCCA TTACCGGAGC 
CGCTACCAGG ACGGAGTCTA CTGGGCTGAG TTCCGAGGAG GCTCTTACTC ACTCAAGAAA 
GTGGTGATGA TGATCCGACC GAACCCCAAC ACCTTCCACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_036230.1
CDS	501..1982
Translation	MRPLCVTCWWLGLLAAMGAVAGQEDGFEGTEEGSPREFIYLNRYKRAGESQDKCTYTFIVPQQRVTGAICVNSKEPEVLLENRVHKQELELLNNELLKQKRQIETLQQLVEVDGGIVSEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALELSQLENRILNQTADMLQLASKYKDLEHKYQHLATLAHNQSEIIAQLEEHCQRVPSARPVPQPPPAAPPRVYQPPTYNRIINQISTNEIQSDQNLKVLPPPLPTMPTLTSLPSSTDKPSGPWRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESEYYKLRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRPNPNTFH

Target ORF information:

RefSeq Version	NM_012098.2
Organism	Homo sapiens(human)
Definition	Homo sapiens angiopoietin like 2 (ANGPTL2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_012098.2

ORF Insert Sequence:

ATGAGGCCAC TGTGCGTGAC ATGCTGGTGG CTCGGACTGC TGGCTGCCAT GGGAGCTGTT 
GCAGGCCAGG AGGACGGTTT TGAGGGCACT GAGGAGGGCT CGCCAAGAGA GTTCATTTAC 
CTAAACAGGT ACAAGCGGGC GGGCGAGTCC CAGGACAAGT GCACCTACAC CTTCATTGTG 
CCCCAGCAGC GGGTCACGGG TGCCATCTGC GTCAACTCCA AGGAGCCTGA GGTGCTTCTG 
GAGAACCGAG TGCATAAGCA GGAGCTAGAG CTGCTCAACA ATGAGCTGCT CAAGCAGAAG 
CGGCAGATCG AGACGCTGCA GCAGCTGGTG GAGGTGGACG GCGGCATTGT GAGCGAGGTG 
AAGCTGCTGC GCAAGGAGAG CCGCAACATG AACTCGCGGG TCACGCAGCT CTACATGCAG 
CTCCTGCACG AGATCATCCG CAAGCGGGAC AACGCGTTGG AGCTCTCCCA GCTGGAGAAC 
AGGATCCTGA ACCAGACAGC CGACATGCTG CAGCTGGCCA GCAAGTACAA GGACCTGGAG 
CACAAGTACC AGCACCTGGC CACACTGGCC CACAACCAAT CAGAGATCAT CGCGCAGCTT 
GAGGAGCACT GCCAGAGGGT GCCCTCGGCC AGGCCCGTCC CCCAGCCACC CCCCGCTGCC 
CCGCCCCGGG TCTACCAACC ACCCACCTAC AACCGCATCA TCAACCAGAT CTCTACCAAC 
GAGATCCAGA GTGACCAGAA CCTGAAGGTG CTGCCACCCC CTCTGCCCAC TATGCCCACT 
CTCACCAGCC TCCCATCTTC CACCGACAAG CCGTCGGGCC CATGGAGAGA CTGCCTGCAG 
GCCCTGGAGG ATGGCCACGA CACCAGCTCC ATCTACCTGG TGAAGCCGGA GAACACCAAC 
CGCCTCATGC AGGTGTGGTG CGACCAGAGA CACGACCCCG GGGGCTGGAC CGTCATCCAG 
AGACGCCTGG ATGGCTCTGT TAACTTCTTC AGGAACTGGG AGACGTACAA GCAAGGGTTT 
GGGAACATTG ACGGCGAATA CTGGCTGGGC CTGGAGAACA TTTACTGGCT GACGAACCAA 
GGCAACTACA AACTCCTGGT GACCATGGAG GACTGGTCCG GCCGCAAAGT CTTTGCAGAA 
TACGCCAGTT TCCGCCTGGA ACCTGAGAGC GAGTATTATA AGCTGCGGCT GGGGCGCTAC 
CATGGCAATG CGGGTGACTC CTTTACATGG CACAACGGCA AGCAGTTCAC CACCCTGGAC 
AGAGATCATG ATGTCTACAC AGGAAACTGT GCCCACTACC AGAAGGGAGG CTGGTGGTAT 
AACGCCTGTG CCCACTCCAA CCTCAACGGG GTCTGGTACC GCGGGGGCCA TTACCGGAGC 
CGCTACCAGG ACGGAGTCTA CTGGGCTGAG TTCCGAGGAG GCTCTTACTC ACTCAAGAAA 
GTGGTGATGA TGATCCGACC GAACCCCAAC ACCTTCCACT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ANGPTL2 ( XM_006717030.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006717093.1 Homo sapiens angiopoietin like 2 (ANGPTL2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu43141
Clone ID Related Accession (Same CDS sequence)	XM_006717030.3 , XM_006717030.4
Accession Version	XM_006717030.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 825bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	angiopoietin-related protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006717030.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGCCAC TGTGCGTGAC ATGCTGGTGG CTCGGACTGC TGGCTGCCAT GGGAGCTGTT 
GCAGGCCAGG AGGACGGTTT TGAGGGCACT GAGGAGGGCT CGCCAAGAGA GTTCATTTAC 
CTAAACAGGT ACAAGCGGGC GGGCGAGTCC CAGGACAAGT GCACCTACAC CTTCATTGTG 
CCCCAGCAGC GGGTCACGGG TGCCATCTGC GTCAACTCCA AGGAGCCTGA GGTGCTTCTG 
GAGAACCGAG TGCATAAGCA GGAGCTAGAG CTGCTCAACA ATGAGCTGCT CAAGCAGAAG 
CGGCAGATCG AGACGCTGCA GCAGCTGGTG GAGGTGGACG GCGGCATTGT GAGCGAGGTG 
AAGCTGCTGC GCAAGGAGAG CCGCAACATG AACTCGCGGG TCACGCAGCT CTACATGCAG 
CTCCTGCACG AGATCATCCG CAAGCGGGAC AACGCGTTGG AGCTCTCCCA GCTGGAGAAC 
AGGATCCTGA ACCAGACAGC CGACATGCTG CAGCTGGCCA GCAAGTACAA GGACCTGGAG 
CACAAGTACC AGCACCTGGC CACACTGGCC CACAACCAAT CAGAGATCAT CGCGCAGCTT 
GAGGAGCACT GCCAGAGGGT GCCCTCGGCC AGGCCCGTCC CCCAGCCACC CCCCGCTGCC 
CCGCCCCGGG TCTACCAACC ACCCACCTAC AACCGCATCA TCAACCAGAT CTCTACCAAC 
GAGATCCAGA GTGACCAGAA CCTGAAGGTG CTGCCACCCC CTCTGCCCAC TATGCCCACT 
CTCACCAGCC TCCCATCTTC CACCGACAAG CCGTCGGGAC TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006717093.1
CDS	539..1363
Translation	MRPLCVTCWWLGLLAAMGAVAGQEDGFEGTEEGSPREFIYLNRYKRAGESQDKCTYTFIVPQQRVTGAICVNSKEPEVLLENRVHKQELELLNNELLKQKRQIETLQQLVEVDGGIVSEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALELSQLENRILNQTADMLQLASKYKDLEHKYQHLATLAHNQSEIIAQLEEHCQRVPSARPVPQPPPAAPPRVYQPPTYNRIINQISTNEIQSDQNLKVLPPPLPTMPTLTSLPSSTDKPSGL

Target ORF information:

RefSeq Version	XM_006717030.3
Organism	Homo sapiens(human)
Definition	Homo sapiens angiopoietin like 2 (ANGPTL2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006717030.3

ORF Insert Sequence:

ATGAGGCCAC TGTGCGTGAC ATGCTGGTGG CTCGGACTGC TGGCTGCCAT GGGAGCTGTT 
GCAGGCCAGG AGGACGGTTT TGAGGGCACT GAGGAGGGCT CGCCAAGAGA GTTCATTTAC 
CTAAACAGGT ACAAGCGGGC GGGCGAGTCC CAGGACAAGT GCACCTACAC CTTCATTGTG 
CCCCAGCAGC GGGTCACGGG TGCCATCTGC GTCAACTCCA AGGAGCCTGA GGTGCTTCTG 
GAGAACCGAG TGCATAAGCA GGAGCTAGAG CTGCTCAACA ATGAGCTGCT CAAGCAGAAG 
CGGCAGATCG AGACGCTGCA GCAGCTGGTG GAGGTGGACG GCGGCATTGT GAGCGAGGTG 
AAGCTGCTGC GCAAGGAGAG CCGCAACATG AACTCGCGGG TCACGCAGCT CTACATGCAG 
CTCCTGCACG AGATCATCCG CAAGCGGGAC AACGCGTTGG AGCTCTCCCA GCTGGAGAAC 
AGGATCCTGA ACCAGACAGC CGACATGCTG CAGCTGGCCA GCAAGTACAA GGACCTGGAG 
CACAAGTACC AGCACCTGGC CACACTGGCC CACAACCAAT CAGAGATCAT CGCGCAGCTT 
GAGGAGCACT GCCAGAGGGT GCCCTCGGCC AGGCCCGTCC CCCAGCCACC CCCCGCTGCC 
CCGCCCCGGG TCTACCAACC ACCCACCTAC AACCGCATCA TCAACCAGAT CTCTACCAAC 
GAGATCCAGA GTGACCAGAA CCTGAAGGTG CTGCCACCCC CTCTGCCCAC TATGCCCACT 
CTCACCAGCC TCCCATCTTC CACCGACAAG CCGTCGGGAC TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ANGPTL2 ( XM_006717030.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_006717093.1 Homo sapiens angiopoietin like 2 (ANGPTL2), transcript variant X1, mRNA.

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CloneID	OHu43141
Clone ID Related Accession (Same CDS sequence)	XM_006717030.3 , XM_006717030.4
Accession Version	XM_006717030.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 825bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	angiopoietin-related protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006717030.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGCCAC TGTGCGTGAC ATGCTGGTGG CTCGGACTGC TGGCTGCCAT GGGAGCTGTT 
GCAGGCCAGG AGGACGGTTT TGAGGGCACT GAGGAGGGCT CGCCAAGAGA GTTCATTTAC 
CTAAACAGGT ACAAGCGGGC GGGCGAGTCC CAGGACAAGT GCACCTACAC CTTCATTGTG 
CCCCAGCAGC GGGTCACGGG TGCCATCTGC GTCAACTCCA AGGAGCCTGA GGTGCTTCTG 
GAGAACCGAG TGCATAAGCA GGAGCTAGAG CTGCTCAACA ATGAGCTGCT CAAGCAGAAG 
CGGCAGATCG AGACGCTGCA GCAGCTGGTG GAGGTGGACG GCGGCATTGT GAGCGAGGTG 
AAGCTGCTGC GCAAGGAGAG CCGCAACATG AACTCGCGGG TCACGCAGCT CTACATGCAG 
CTCCTGCACG AGATCATCCG CAAGCGGGAC AACGCGTTGG AGCTCTCCCA GCTGGAGAAC 
AGGATCCTGA ACCAGACAGC CGACATGCTG CAGCTGGCCA GCAAGTACAA GGACCTGGAG 
CACAAGTACC AGCACCTGGC CACACTGGCC CACAACCAAT CAGAGATCAT CGCGCAGCTT 
GAGGAGCACT GCCAGAGGGT GCCCTCGGCC AGGCCCGTCC CCCAGCCACC CCCCGCTGCC 
CCGCCCCGGG TCTACCAACC ACCCACCTAC AACCGCATCA TCAACCAGAT CTCTACCAAC 
GAGATCCAGA GTGACCAGAA CCTGAAGGTG CTGCCACCCC CTCTGCCCAC TATGCCCACT 
CTCACCAGCC TCCCATCTTC CACCGACAAG CCGTCGGGAC TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006717093.1
CDS	420..1244
Translation	MRPLCVTCWWLGLLAAMGAVAGQEDGFEGTEEGSPREFIYLNRYKRAGESQDKCTYTFIVPQQRVTGAICVNSKEPEVLLENRVHKQELELLNNELLKQKRQIETLQQLVEVDGGIVSEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALELSQLENRILNQTADMLQLASKYKDLEHKYQHLATLAHNQSEIIAQLEEHCQRVPSARPVPQPPPAAPPRVYQPPTYNRIINQISTNEIQSDQNLKVLPPPLPTMPTLTSLPSSTDKPSGL

Target ORF information:

RefSeq Version	XM_006717030.4
Organism	Homo sapiens(human)
Definition	Homo sapiens angiopoietin like 2 (ANGPTL2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006717030.4

ORF Insert Sequence:

ATGAGGCCAC TGTGCGTGAC ATGCTGGTGG CTCGGACTGC TGGCTGCCAT GGGAGCTGTT 
GCAGGCCAGG AGGACGGTTT TGAGGGCACT GAGGAGGGCT CGCCAAGAGA GTTCATTTAC 
CTAAACAGGT ACAAGCGGGC GGGCGAGTCC CAGGACAAGT GCACCTACAC CTTCATTGTG 
CCCCAGCAGC GGGTCACGGG TGCCATCTGC GTCAACTCCA AGGAGCCTGA GGTGCTTCTG 
GAGAACCGAG TGCATAAGCA GGAGCTAGAG CTGCTCAACA ATGAGCTGCT CAAGCAGAAG 
CGGCAGATCG AGACGCTGCA GCAGCTGGTG GAGGTGGACG GCGGCATTGT GAGCGAGGTG 
AAGCTGCTGC GCAAGGAGAG CCGCAACATG AACTCGCGGG TCACGCAGCT CTACATGCAG 
CTCCTGCACG AGATCATCCG CAAGCGGGAC AACGCGTTGG AGCTCTCCCA GCTGGAGAAC 
AGGATCCTGA ACCAGACAGC CGACATGCTG CAGCTGGCCA GCAAGTACAA GGACCTGGAG 
CACAAGTACC AGCACCTGGC CACACTGGCC CACAACCAAT CAGAGATCAT CGCGCAGCTT 
GAGGAGCACT GCCAGAGGGT GCCCTCGGCC AGGCCCGTCC CCCAGCCACC CCCCGCTGCC 
CCGCCCCGGG TCTACCAACC ACCCACCTAC AACCGCATCA TCAACCAGAT CTCTACCAAC 
GAGATCCAGA GTGACCAGAA CCTGAAGGTG CTGCCACCCC CTCTGCCCAC TATGCCCACT 
CTCACCAGCC TCCCATCTTC CACCGACAAG CCGTCGGGAC TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Angiopoietin-like protein as a novel marker for liver fibrosis in chronic hepatitis B patients with normal to minimally raised ALT.
BMC infectious diseases17(1)650(2017 Sep)
Deng Y,Zhao H,Zhou J,Yan L,Wang G,

High Circulating Levels of ANGPTL2: Beyond a Clinical Marker of Systemic Inflammation.
Oxidative medicine and cellular longevity20171096385(2017)
Thorin-Trescases N,Thorin E

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ANGPTL2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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