LARS2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LARS2
Entrez Gene ID	23395
Full Name	leucyl-tRNA synthetase 2, mitochondrial
Synonyms	HLASA,LEURS,PRLTS4,mtLeuRS
General protein information	Preferred Names leucyl-tRNA synthetase 2, mitochondrial Names probable leucine--tRNA ligase, mitochondrial leucine tRNA ligase 2, mitochondrial leucine tRNA ligase 2, mitocondrial leucine translase probable leucyl-tRNA synthetase, mitochondrial
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3p21.31
Summary	This gene encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. [provided by RefSeq, Jul 2008].
Disorder MIM:	604544
Disorder Html:	Perrault syndrome 4, 615300 (3); ?Hydrops, lactic acidosis, and sideroblastic anemia, 617021 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_017006042.1	XP_016861531.1	probable leucine--tRNA ligase, mitochondrial isoform X3
NM_015340.4	NP_056155.1	probable leucine--tRNA ligase, mitochondrial
NM_015340.3	NP_056155.1	probable leucine--tRNA ligase, mitochondrial
XM_011533554.2	XP_011531856.1	probable leucine--tRNA ligase, mitochondrial isoform X2
XM_005265006.1	XP_005265063.1	probable leucine--tRNA ligase, mitochondrial isoform X1
XM_005265006.2	XP_005265063.1	probable leucine--tRNA ligase, mitochondrial isoform X1
NM_001368263.1	NP_001355192.1	probable leucine--tRNA ligase, mitochondrial

Pathways from BioSystems

Homologies

	LARS2	XP_001114552.2
Homo sapiens (human)	LARS2	NP_056155.1
Kluyveromyces lactis	KLLA0E05325g	XP_454185.1
Magnaporthe oryzae (rice blast fungus)	MGG_04042	XP_003719800.1
Arabidopsis thaliana (thale cress)	EMB2369	NP_192344.1
Canis lupus familiaris (dog)	LARS2	XP_005632695.1
Rattus norvegicus (Norway rat)	Lars2	NP_001102257.1
Danio rerio (zebrafish)	lars2	NP_001099171.1
Drosophila melanogaster (fruit fly)	Aats-leu	NP_647932.1
Schizosaccharomyces pombe (fission yeast)	SPAC4G8.09	NP_593069.1
Neurospora crassa	NCU03814	XP_961203.1
Pan troglodytes (chimpanzee)	LARS2	XP_001147749.1
Mus musculus (house mouse)	Lars2	NP_694808.1
Caenorhabditis elegans (roundworm)	lars-2	NP_001021875.1
Saccharomyces cerevisiae (baker's yeast)	NAM2	NP_013486.3
Gallus gallus (chicken)	LARS2	XP_004939517.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002014	XP_321043.4
Eremothecium gossypii	AGOS_AER043C	NP_984903.1
Xenopus tropicalis (tropical clawed frog)	lars2	XP_002938354.2

Gene Ontology
Bibliography

Related articles in PubMed

Biallelic mutations in LARS2 can cause Perrault syndrome type 2 with neurologic symptoms.
Kosaki R, Horikawa R, Fujii E, Kosaki K
American journal of medical genetics. Part A176(2)404-408(2018 Feb)

Knockdown of IARS2 suppressed growth of gastric cancer cells by regulating the phosphorylation of cell cycle-related proteins.
Fang Z, Wang X, Yan Q, Zhang S, Li Y
Molecular and cellular biochemistry(2017 Oct)

Expanding the genotypic spectrum of Perrault syndrome.
Demain LA, Urquhart JE, O'Sullivan J, Williams SG, Bhaskar SS, Jenkinson EM, Lourenco CM, Heiberg A, Pearce SH, Shalev SA, Yue WW, Mackinnon S, Munro KJ, Newbury-Ecob R, Becker K, Kim MJ, O' Keefe RT, Newman WG
Clinical genetics91(2)302-312(2017 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ere we present eight families affected by Perrault syndrome. In five families we identified novel or previously reported variants in HSD17B4, LARS2, CLPP and C10orf2
Title: Expanding the genotypic spectrum of Perrault syndrome.

This represents the first independent replication of the involvement of LARS2 mutations in Perrault syndrome, contributing valuable information for the further understanding of this disease
Title: First independent replication of the involvement of LARS2 in Perrault syndrome by whole-exome sequencing of an Italian family.

analysis of the CP1 domain in human mitochondrial leucyl-tRNA synthetase
Title: Degenerate connective polypeptide 1 (CP1) domain from human mitochondrial leucyl-tRNA synthetase.

Leucyl tRNA synthetase is able to partially rescue defects caused by mutations in non-cognate itochondrial-tRNAs.
Title: Human mitochondrial leucyl tRNA synthetase can suppress non cognate pathogenic mt-tRNA mutations.

Mutations in LARS2, encoding mitochondrial leucyl-tRNA synthetase, lead to premature ovarian failure and hearing loss in Perrault syndrome.
Title: Mutations in LARS2, encoding mitochondrial leucyl-tRNA synthetase, lead to premature ovarian failure and hearing loss in Perrault syndrome.

The following LARS2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LARS2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18528	NM_015340.4 Latest version!	Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu18528	NM_001368263.1 Latest version!	Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu18528	XM_005265006.2 Latest version!	Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu66139	XM_011533554.2 Latest version!	Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu93991	XM_017006042.1 Latest version!	Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OHu18528	NM_015340.3	Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu18528	XM_005265006.1	Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LARS2 ( NM_015340.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_056155.1 Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18528
Clone ID Related Accession (Same CDS sequence)	NM_015340.4 , NM_015340.3 , XM_005265006.1 , XM_005265006.2 , NM_001368263.1
Accession Version	NM_015340.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2712bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	probable leucine--tRNA ligase, mitochondrial
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC006515.7, BI463427.1, D21851.1 and AC099539.2. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_015340.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC025989.2, D21851.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000645846.2/ ENSP00000495093.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTTCTG TTTGGCAGAG ATTGGGTTTT TATGCCTCTC TTCTGAAAAG ACAGCTAAAT 
GGTGGGCCAG ATGTCATCAA GTGGGAAAGG AGAGTAATTC CCGGATGTAC CAGAAGCATC 
TACAGTGCCA CGGGAAAGTG GACAAAAGAG TATACATTGC AGACAAGAAA GGATGTTGAG 
AAATGGTGGC ATCAACGAAT AAAAGAACAG GCCTCCAAAA TTTCAGAAGC TGATAAATCG 
AAGCCAAAAT TTTACGTGCT TTCCATGTTC CCTTATCCTT CTGGTAAGCT GCACATGGGC 
CATGTGCGTG TCTACACCAT CAGCGACACC ATAGCACGGT TCCAGAAGAT GAGAGGGATG 
CAGGTCATCA ACCCCATGGG ATGGGATGCT TTTGGATTGC CTGCTGAAAA TGCCGCAGTC 
GAGAGGAATC TACATCCACA AAGTTGGACA CAAAGTAATA TTAAACACAT GAGGAAACAG 
CTTGATCGTC TGGGCCTGTG TTTCAGCTGG GATAGGGAAA TAACTACGTG TTTGCCAGAT 
TACTACAAGT GGACTCAGTA TCTCTTTATT AAACTGTATG AGGCTGGGCT GGCCTATCAA 
AAGGAGGCCC TGGTTAACTG GGACCCAGTG GATCAAACAG TGCTTGCCAA TGAGCAGGTG 
GATGAACATG GCTGTTCATG GCGTTCTGGA GCAAAGGTGG AACAGAAGTA CCTCAGACAA 
TGGTTTATTA AGACAACCGC TTATGCAAAG GCCATGCAGG ACGCGTTGGC AGACCTTCCA 
GAATGGTATG GAATAAAAGG CATGCAAGCC CACTGGATTG GGGACTGTGT GGGCTGCCAC 
CTGGACTTCA CATTAAAGGT TCATGGGCAA GCCACGGGCG AAAAGCTGAC TGCCTATACG 
GCCACCCCTG AAGCCATTTA TGGCACCTCC CACGTGGCCA TCTCGCCCAG CCACAGACTC 
CTACATGGGC ACAGCTCTCT GAAGGAAGCC TTGAGGATGG CCCTTGTCCC TGGCAAAGAT 
TGCCTCACGC CTGTAATGGC TGTGAACATG CTTACCCAGC AGGAGGTCCC TGTCGTTATT 
TTGGCCAAAG CTGACTTGGA AGGCTCTCTG GATTCAAAAA TAGGAATTCC CAGTACTAGC 
TCAGAGGACA CCATCTTAGC CCAAACCCTG GGCCTGGCCT ACTCTGAAGT CATTGAAACT 
TTGCCAGATG GCACAGAGAG ACTGAGCAGC TCTGCTGAGT TCACAGGTAT GACCCGGCAG 
GATGCTTTTC TAGCCCTGAC TCAGAAAGCC CGGGGGAAGA GAGTGGGTGG AGACGTGACA 
AGTGATAAAC TGAAAGACTG GCTGATTTCA CGGCAGCGGT ACTGGGGCAC ACCAATCCCC 
ATTGTCCACT GCCCAGTCTG TGGCCCCACA CCTGTGCCCC TGGAGGACTT GCCTGTGACC 
CTGCCCAACA TCGCGTCTTT CACTGGCAAG GGAGGCCCCC CACTGGCCAT GGCTTCAGAG 
TGGGTGAACT GCTCCTGCCC AAGGTGCAAG GGAGCAGCCA AGAGAGAGAC AGACACGATG 
GATACCTTTG TTGATTCTGC TTGGTACTAC TTCAGATACA CTGACCCTCA TAATCCACAC 
AGCCCTTTTA ACACAGCAGT GGCCGATTAC TGGATGCCTG TGGATTTGTA CATTGGAGGG 
AAAGAACATG CCGTCATGCA CTTGTTCTAT GCAAGATTCT TTAGTCATTT TTGCCATGAT 
CAAAAAATGG TTAAACATAG GGAGCCTTTT CATAAGCTGC TGGCCCAAGG CCTTATCAAG 
GGGCAGACAT TCCGCCTACC ATCTGGACAG TATCTACAGA GAGAGGAAGT GGATCTCACA 
GGTTCCGTTC CTGTTCATGC AAAAACGAAA GAGAAGTTAG AGGTGACGTG GGAGAAGATG 
AGTAAGTCCA AACACAACGG GGTGGACCCA GAGGAAGTTG TGGAGCAGTA TGGGATCGAC 
ACGATTCGGC TCTACATCCT TTTTGCTGCC CCTCCTGAGA AGGATATCTT GTGGGATGTG 
AAAACTGATG CTCTCCCTGG GGTGCTGAGA TGGCAACAAC GACTGTGGAC CTTGACAACT 
CGGTTTATTG AGGCCAGGGC TTCTGGGAAG TCTCCCCAGC CTCAGCTGCT GAGTAACAAG 
GAGAAAGCTG AGGCCAGGAA GCTCTGGGAG TACAAGAACT CCGTCATCTC TCAGGTGACC 
ACCCATTTCA CAGAGGACTT CTCACTGAAT TCTGCAATTT CTCAGCTGAT GGGACTCAGC 
AATGCCCTCT CGCAAGCCTC TCAGAGCGTC ATTCTCCACA GCCCCGAGTT TGAGGATGCT 
TTGTGTGCCC TGATGGTAAT GGCTGCTCCA CTGGCCCCTC ATGTAACCTC AGAGATCTGG 
GCAGGCCTGG CGCTGGTGCC GAGGAAGCTC TGTGCCCACT ACACTTGGGA TGCCAGTGTG 
CTGCTCCAGG CATGGCCTGC TGTGGACCCG GAGTTCCTGC AGCAGCCTGA GGTTGTCCAG 
ATGGCAGTTC TGATCAACAA TAAAGCTTGT GGCAAAATTC CTGTGCCCCA ACAAGTTGCC 
CGGGACCAGG ACAAAGTCCA CGAATTTGTT CTTCAAAGCG AGCTGGGTGT CAGGCTTTTG 
CAAGGACGAA GCATCAAGAA GTCCTTCCTT TCCCCGAGAA CTGCCCTCAT CAACTTCCTG 
GTGCAAGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056155.1
CDS	193..2904
Translation	MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVHGQATGEKLTAYTATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMALVPGKDCLTPVMAVNMLTQQEVPVVILAKADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPDGTERLSSSAEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMASEWVNCSCPRCKGAAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNKEKAEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDALCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQMAVLINNKACGKIPVPQQVARDQDKVHEFVLQSELGVRLLQGRSIKKSFLSPRTALINFLVQD

Target ORF information:

RefSeq Version	NM_015340.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015340.4

ORF Insert Sequence:

ATGGCTTCTG TTTGGCAGAG ATTGGGTTTT TATGCCTCTC TTCTGAAAAG ACAGCTAAAT 
GGTGGGCCAG ATGTCATCAA GTGGGAAAGG AGAGTAATTC CCGGATGTAC CAGAAGCATC 
TACAGTGCCA CGGGAAAGTG GACAAAAGAG TATACATTGC AGACAAGAAA GGATGTTGAG 
AAATGGTGGC ATCAACGAAT AAAAGAACAG GCCTCCAAAA TTTCAGAAGC TGATAAATCG 
AAGCCAAAAT TTTACGTGCT TTCCATGTTC CCTTATCCTT CTGGTAAGCT GCACATGGGC 
CATGTGCGTG TCTACACCAT CAGCGACACC ATAGCACGGT TCCAGAAGAT GAGAGGGATG 
CAGGTCATCA ACCCCATGGG ATGGGATGCT TTTGGATTGC CTGCTGAAAA TGCCGCAGTC 
GAGAGGAATC TACATCCACA AAGTTGGACA CAAAGTAATA TTAAACACAT GAGGAAACAG 
CTTGATCGTC TGGGCCTGTG TTTCAGCTGG GATAGGGAAA TAACTACGTG TTTGCCAGAT 
TACTACAAGT GGACTCAGTA TCTCTTTATT AAACTGTATG AGGCTGGGCT GGCCTATCAA 
AAGGAGGCCC TGGTTAACTG GGACCCAGTG GATCAAACAG TGCTTGCCAA TGAGCAGGTG 
GATGAACATG GCTGTTCATG GCGTTCTGGA GCAAAGGTGG AACAGAAGTA CCTCAGACAA 
TGGTTTATTA AGACAACCGC TTATGCAAAG GCCATGCAGG ACGCGTTGGC AGACCTTCCA 
GAATGGTATG GAATAAAAGG CATGCAAGCC CACTGGATTG GGGACTGTGT GGGCTGCCAC 
CTGGACTTCA CATTAAAGGT TCATGGGCAA GCCACGGGCG AAAAGCTGAC TGCCTATACG 
GCCACCCCTG AAGCCATTTA TGGCACCTCC CACGTGGCCA TCTCGCCCAG CCACAGACTC 
CTACATGGGC ACAGCTCTCT GAAGGAAGCC TTGAGGATGG CCCTTGTCCC TGGCAAAGAT 
TGCCTCACGC CTGTAATGGC TGTGAACATG CTTACCCAGC AGGAGGTCCC TGTCGTTATT 
TTGGCCAAAG CTGACTTGGA AGGCTCTCTG GATTCAAAAA TAGGAATTCC CAGTACTAGC 
TCAGAGGACA CCATCTTAGC CCAAACCCTG GGCCTGGCCT ACTCTGAAGT CATTGAAACT 
TTGCCAGATG GCACAGAGAG ACTGAGCAGC TCTGCTGAGT TCACAGGTAT GACCCGGCAG 
GATGCTTTTC TAGCCCTGAC TCAGAAAGCC CGGGGGAAGA GAGTGGGTGG AGACGTGACA 
AGTGATAAAC TGAAAGACTG GCTGATTTCA CGGCAGCGGT ACTGGGGCAC ACCAATCCCC 
ATTGTCCACT GCCCAGTCTG TGGCCCCACA CCTGTGCCCC TGGAGGACTT GCCTGTGACC 
CTGCCCAACA TCGCGTCTTT CACTGGCAAG GGAGGCCCCC CACTGGCCAT GGCTTCAGAG 
TGGGTGAACT GCTCCTGCCC AAGGTGCAAG GGAGCAGCCA AGAGAGAGAC AGACACGATG 
GATACCTTTG TTGATTCTGC TTGGTACTAC TTCAGATACA CTGACCCTCA TAATCCACAC 
AGCCCTTTTA ACACAGCAGT GGCCGATTAC TGGATGCCTG TGGATTTGTA CATTGGAGGG 
AAAGAACATG CCGTCATGCA CTTGTTCTAT GCAAGATTCT TTAGTCATTT TTGCCATGAT 
CAAAAAATGG TTAAACATAG GGAGCCTTTT CATAAGCTGC TGGCCCAAGG CCTTATCAAG 
GGGCAGACAT TCCGCCTACC ATCTGGACAG TATCTACAGA GAGAGGAAGT GGATCTCACA 
GGTTCCGTTC CTGTTCATGC AAAAACGAAA GAGAAGTTAG AGGTGACGTG GGAGAAGATG 
AGTAAGTCCA AACACAACGG GGTGGACCCA GAGGAAGTTG TGGAGCAGTA TGGGATCGAC 
ACGATTCGGC TCTACATCCT TTTTGCTGCC CCTCCTGAGA AGGATATCTT GTGGGATGTG 
AAAACTGATG CTCTCCCTGG GGTGCTGAGA TGGCAACAAC GACTGTGGAC CTTGACAACT 
CGGTTTATTG AGGCCAGGGC TTCTGGGAAG TCTCCCCAGC CTCAGCTGCT GAGTAACAAG 
GAGAAAGCTG AGGCCAGGAA GCTCTGGGAG TACAAGAACT CCGTCATCTC TCAGGTGACC 
ACCCATTTCA CAGAGGACTT CTCACTGAAT TCTGCAATTT CTCAGCTGAT GGGACTCAGC 
AATGCCCTCT CGCAAGCCTC TCAGAGCGTC ATTCTCCACA GCCCCGAGTT TGAGGATGCT 
TTGTGTGCCC TGATGGTAAT GGCTGCTCCA CTGGCCCCTC ATGTAACCTC AGAGATCTGG 
GCAGGCCTGG CGCTGGTGCC GAGGAAGCTC TGTGCCCACT ACACTTGGGA TGCCAGTGTG 
CTGCTCCAGG CATGGCCTGC TGTGGACCCG GAGTTCCTGC AGCAGCCTGA GGTTGTCCAG 
ATGGCAGTTC TGATCAACAA TAAAGCTTGT GGCAAAATTC CTGTGCCCCA ACAAGTTGCC 
CGGGACCAGG ACAAAGTCCA CGAATTTGTT CTTCAAAGCG AGCTGGGTGT CAGGCTTTTG 
CAAGGACGAA GCATCAAGAA GTCCTTCCTT TCCCCGAGAA CTGCCCTCAT CAACTTCCTG 
GTGCAAGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LARS2 ( NM_015340.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_056155.1 Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), mRNA.

Price & Availability↑

CloneID	OHu18528
Clone ID Related Accession (Same CDS sequence)	NM_015340.4 , NM_015340.3 , XM_005265006.1 , XM_005265006.2 , NM_001368263.1
Accession Version	NM_015340.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2712bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	probable leucine--tRNA ligase, mitochondrial
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI463427.1 and D21851.1. This sequence is a reference standard in the RefSeqGene project. On Jan 28, 2004 this sequence version replaced NM_015340.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D21851.1, BC025989.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCTTCTG TTTGGCAGAG ATTGGGTTTT TATGCCTCTC TTCTGAAAAG ACAGCTAAAT 
GGTGGGCCAG ATGTCATCAA GTGGGAAAGG AGAGTAATTC CCGGATGTAC CAGAAGCATC 
TACAGTGCCA CGGGAAAGTG GACAAAAGAG TATACATTGC AGACAAGAAA GGATGTTGAG 
AAATGGTGGC ATCAACGAAT AAAAGAACAG GCCTCCAAAA TTTCAGAAGC TGATAAATCG 
AAGCCAAAAT TTTACGTGCT TTCCATGTTC CCTTATCCTT CTGGTAAGCT GCACATGGGC 
CATGTGCGTG TCTACACCAT CAGCGACACC ATAGCACGGT TCCAGAAGAT GAGAGGGATG 
CAGGTCATCA ACCCCATGGG ATGGGATGCT TTTGGATTGC CTGCTGAAAA TGCCGCAGTC 
GAGAGGAATC TACATCCACA AAGTTGGACA CAAAGTAATA TTAAACACAT GAGGAAACAG 
CTTGATCGTC TGGGCCTGTG TTTCAGCTGG GATAGGGAAA TAACTACGTG TTTGCCAGAT 
TACTACAAGT GGACTCAGTA TCTCTTTATT AAACTGTATG AGGCTGGGCT GGCCTATCAA 
AAGGAGGCCC TGGTTAACTG GGACCCAGTG GATCAAACAG TGCTTGCCAA TGAGCAGGTG 
GATGAACATG GCTGTTCATG GCGTTCTGGA GCAAAGGTGG AACAGAAGTA CCTCAGACAA 
TGGTTTATTA AGACAACCGC TTATGCAAAG GCCATGCAGG ACGCGTTGGC AGACCTTCCA 
GAATGGTATG GAATAAAAGG CATGCAAGCC CACTGGATTG GGGACTGTGT GGGCTGCCAC 
CTGGACTTCA CATTAAAGGT TCATGGGCAA GCCACGGGCG AAAAGCTGAC TGCCTATACG 
GCCACCCCTG AAGCCATTTA TGGCACCTCC CACGTGGCCA TCTCGCCCAG CCACAGACTC 
CTACATGGGC ACAGCTCTCT GAAGGAAGCC TTGAGGATGG CCCTTGTCCC TGGCAAAGAT 
TGCCTCACGC CTGTAATGGC TGTGAACATG CTTACCCAGC AGGAGGTCCC TGTCGTTATT 
TTGGCCAAAG CTGACTTGGA AGGCTCTCTG GATTCAAAAA TAGGAATTCC CAGTACTAGC 
TCAGAGGACA CCATCTTAGC CCAAACCCTG GGCCTGGCCT ACTCTGAAGT CATTGAAACT 
TTGCCAGATG GCACAGAGAG ACTGAGCAGC TCTGCTGAGT TCACAGGTAT GACCCGGCAG 
GATGCTTTTC TAGCCCTGAC TCAGAAAGCC CGGGGGAAGA GAGTGGGTGG AGACGTGACA 
AGTGATAAAC TGAAAGACTG GCTGATTTCA CGGCAGCGGT ACTGGGGCAC ACCAATCCCC 
ATTGTCCACT GCCCAGTCTG TGGCCCCACA CCTGTGCCCC TGGAGGACTT GCCTGTGACC 
CTGCCCAACA TCGCGTCTTT CACTGGCAAG GGAGGCCCCC CACTGGCCAT GGCTTCAGAG 
TGGGTGAACT GCTCCTGCCC AAGGTGCAAG GGAGCAGCCA AGAGAGAGAC AGACACGATG 
GATACCTTTG TTGATTCTGC TTGGTACTAC TTCAGATACA CTGACCCTCA TAATCCACAC 
AGCCCTTTTA ACACAGCAGT GGCCGATTAC TGGATGCCTG TGGATTTGTA CATTGGAGGG 
AAAGAACATG CCGTCATGCA CTTGTTCTAT GCAAGATTCT TTAGTCATTT TTGCCATGAT 
CAAAAAATGG TTAAACATAG GGAGCCTTTT CATAAGCTGC TGGCCCAAGG CCTTATCAAG 
GGGCAGACAT TCCGCCTACC ATCTGGACAG TATCTACAGA GAGAGGAAGT GGATCTCACA 
GGTTCCGTTC CTGTTCATGC AAAAACGAAA GAGAAGTTAG AGGTGACGTG GGAGAAGATG 
AGTAAGTCCA AACACAACGG GGTGGACCCA GAGGAAGTTG TGGAGCAGTA TGGGATCGAC 
ACGATTCGGC TCTACATCCT TTTTGCTGCC CCTCCTGAGA AGGATATCTT GTGGGATGTG 
AAAACTGATG CTCTCCCTGG GGTGCTGAGA TGGCAACAAC GACTGTGGAC CTTGACAACT 
CGGTTTATTG AGGCCAGGGC TTCTGGGAAG TCTCCCCAGC CTCAGCTGCT GAGTAACAAG 
GAGAAAGCTG AGGCCAGGAA GCTCTGGGAG TACAAGAACT CCGTCATCTC TCAGGTGACC 
ACCCATTTCA CAGAGGACTT CTCACTGAAT TCTGCAATTT CTCAGCTGAT GGGACTCAGC 
AATGCCCTCT CGCAAGCCTC TCAGAGCGTC ATTCTCCACA GCCCCGAGTT TGAGGATGCT 
TTGTGTGCCC TGATGGTAAT GGCTGCTCCA CTGGCCCCTC ATGTAACCTC AGAGATCTGG 
GCAGGCCTGG CGCTGGTGCC GAGGAAGCTC TGTGCCCACT ACACTTGGGA TGCCAGTGTG 
CTGCTCCAGG CATGGCCTGC TGTGGACCCG GAGTTCCTGC AGCAGCCTGA GGTTGTCCAG 
ATGGCAGTTC TGATCAACAA TAAAGCTTGT GGCAAAATTC CTGTGCCCCA ACAAGTTGCC 
CGGGACCAGG ACAAAGTCCA CGAATTTGTT CTTCAAAGCG AGCTGGGTGT CAGGCTTTTG 
CAAGGACGAA GCATCAAGAA GTCCTTCCTT TCCCCGAGAA CTGCCCTCAT CAACTTCCTG 
GTGCAAGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056155.1
CDS	186..2897
Translation	MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVHGQATGEKLTAYTATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMALVPGKDCLTPVMAVNMLTQQEVPVVILAKADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPDGTERLSSSAEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMASEWVNCSCPRCKGAAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNKEKAEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDALCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQMAVLINNKACGKIPVPQQVARDQDKVHEFVLQSELGVRLLQGRSIKKSFLSPRTALINFLVQD

Target ORF information:

RefSeq Version	NM_015340.3
Organism	Homo sapiens(human)
Definition	Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015340.3

ORF Insert Sequence:

ATGGCTTCTG TTTGGCAGAG ATTGGGTTTT TATGCCTCTC TTCTGAAAAG ACAGCTAAAT 
GGTGGGCCAG ATGTCATCAA GTGGGAAAGG AGAGTAATTC CCGGATGTAC CAGAAGCATC 
TACAGTGCCA CGGGAAAGTG GACAAAAGAG TATACATTGC AGACAAGAAA GGATGTTGAG 
AAATGGTGGC ATCAACGAAT AAAAGAACAG GCCTCCAAAA TTTCAGAAGC TGATAAATCG 
AAGCCAAAAT TTTACGTGCT TTCCATGTTC CCTTATCCTT CTGGTAAGCT GCACATGGGC 
CATGTGCGTG TCTACACCAT CAGCGACACC ATAGCACGGT TCCAGAAGAT GAGAGGGATG 
CAGGTCATCA ACCCCATGGG ATGGGATGCT TTTGGATTGC CTGCTGAAAA TGCCGCAGTC 
GAGAGGAATC TACATCCACA AAGTTGGACA CAAAGTAATA TTAAACACAT GAGGAAACAG 
CTTGATCGTC TGGGCCTGTG TTTCAGCTGG GATAGGGAAA TAACTACGTG TTTGCCAGAT 
TACTACAAGT GGACTCAGTA TCTCTTTATT AAACTGTATG AGGCTGGGCT GGCCTATCAA 
AAGGAGGCCC TGGTTAACTG GGACCCAGTG GATCAAACAG TGCTTGCCAA TGAGCAGGTG 
GATGAACATG GCTGTTCATG GCGTTCTGGA GCAAAGGTGG AACAGAAGTA CCTCAGACAA 
TGGTTTATTA AGACAACCGC TTATGCAAAG GCCATGCAGG ACGCGTTGGC AGACCTTCCA 
GAATGGTATG GAATAAAAGG CATGCAAGCC CACTGGATTG GGGACTGTGT GGGCTGCCAC 
CTGGACTTCA CATTAAAGGT TCATGGGCAA GCCACGGGCG AAAAGCTGAC TGCCTATACG 
GCCACCCCTG AAGCCATTTA TGGCACCTCC CACGTGGCCA TCTCGCCCAG CCACAGACTC 
CTACATGGGC ACAGCTCTCT GAAGGAAGCC TTGAGGATGG CCCTTGTCCC TGGCAAAGAT 
TGCCTCACGC CTGTAATGGC TGTGAACATG CTTACCCAGC AGGAGGTCCC TGTCGTTATT 
TTGGCCAAAG CTGACTTGGA AGGCTCTCTG GATTCAAAAA TAGGAATTCC CAGTACTAGC 
TCAGAGGACA CCATCTTAGC CCAAACCCTG GGCCTGGCCT ACTCTGAAGT CATTGAAACT 
TTGCCAGATG GCACAGAGAG ACTGAGCAGC TCTGCTGAGT TCACAGGTAT GACCCGGCAG 
GATGCTTTTC TAGCCCTGAC TCAGAAAGCC CGGGGGAAGA GAGTGGGTGG AGACGTGACA 
AGTGATAAAC TGAAAGACTG GCTGATTTCA CGGCAGCGGT ACTGGGGCAC ACCAATCCCC 
ATTGTCCACT GCCCAGTCTG TGGCCCCACA CCTGTGCCCC TGGAGGACTT GCCTGTGACC 
CTGCCCAACA TCGCGTCTTT CACTGGCAAG GGAGGCCCCC CACTGGCCAT GGCTTCAGAG 
TGGGTGAACT GCTCCTGCCC AAGGTGCAAG GGAGCAGCCA AGAGAGAGAC AGACACGATG 
GATACCTTTG TTGATTCTGC TTGGTACTAC TTCAGATACA CTGACCCTCA TAATCCACAC 
AGCCCTTTTA ACACAGCAGT GGCCGATTAC TGGATGCCTG TGGATTTGTA CATTGGAGGG 
AAAGAACATG CCGTCATGCA CTTGTTCTAT GCAAGATTCT TTAGTCATTT TTGCCATGAT 
CAAAAAATGG TTAAACATAG GGAGCCTTTT CATAAGCTGC TGGCCCAAGG CCTTATCAAG 
GGGCAGACAT TCCGCCTACC ATCTGGACAG TATCTACAGA GAGAGGAAGT GGATCTCACA 
GGTTCCGTTC CTGTTCATGC AAAAACGAAA GAGAAGTTAG AGGTGACGTG GGAGAAGATG 
AGTAAGTCCA AACACAACGG GGTGGACCCA GAGGAAGTTG TGGAGCAGTA TGGGATCGAC 
ACGATTCGGC TCTACATCCT TTTTGCTGCC CCTCCTGAGA AGGATATCTT GTGGGATGTG 
AAAACTGATG CTCTCCCTGG GGTGCTGAGA TGGCAACAAC GACTGTGGAC CTTGACAACT 
CGGTTTATTG AGGCCAGGGC TTCTGGGAAG TCTCCCCAGC CTCAGCTGCT GAGTAACAAG 
GAGAAAGCTG AGGCCAGGAA GCTCTGGGAG TACAAGAACT CCGTCATCTC TCAGGTGACC 
ACCCATTTCA CAGAGGACTT CTCACTGAAT TCTGCAATTT CTCAGCTGAT GGGACTCAGC 
AATGCCCTCT CGCAAGCCTC TCAGAGCGTC ATTCTCCACA GCCCCGAGTT TGAGGATGCT 
TTGTGTGCCC TGATGGTAAT GGCTGCTCCA CTGGCCCCTC ATGTAACCTC AGAGATCTGG 
GCAGGCCTGG CGCTGGTGCC GAGGAAGCTC TGTGCCCACT ACACTTGGGA TGCCAGTGTG 
CTGCTCCAGG CATGGCCTGC TGTGGACCCG GAGTTCCTGC AGCAGCCTGA GGTTGTCCAG 
ATGGCAGTTC TGATCAACAA TAAAGCTTGT GGCAAAATTC CTGTGCCCCA ACAAGTTGCC 
CGGGACCAGG ACAAAGTCCA CGAATTTGTT CTTCAAAGCG AGCTGGGTGT CAGGCTTTTG 
CAAGGACGAA GCATCAAGAA GTCCTTCCTT TCCCCGAGAA CTGCCCTCAT CAACTTCCTG 
GTGCAAGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LARS2 ( NM_001368263.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001355192.1 Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), transcript variant 2, mRNA.

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CloneID	OHu18528
Clone ID Related Accession (Same CDS sequence)	NM_015340.4 , NM_015340.3 , XM_005265006.1 , XM_005265006.2 , NM_001368263.1
Accession Version	NM_001368263.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2712bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	probable leucine--tRNA ligase, mitochondrial
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC006515.7, AC092500.2 and AC099539.2. On Jan 31, 2019 this sequence version replaced XM_005265006.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.196135.1, SRR1803611.130320.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTTCTG TTTGGCAGAG ATTGGGTTTT TATGCCTCTC TTCTGAAAAG ACAGCTAAAT 
GGTGGGCCAG ATGTCATCAA GTGGGAAAGG AGAGTAATTC CCGGATGTAC CAGAAGCATC 
TACAGTGCCA CGGGAAAGTG GACAAAAGAG TATACATTGC AGACAAGAAA GGATGTTGAG 
AAATGGTGGC ATCAACGAAT AAAAGAACAG GCCTCCAAAA TTTCAGAAGC TGATAAATCG 
AAGCCAAAAT TTTACGTGCT TTCCATGTTC CCTTATCCTT CTGGTAAGCT GCACATGGGC 
CATGTGCGTG TCTACACCAT CAGCGACACC ATAGCACGGT TCCAGAAGAT GAGAGGGATG 
CAGGTCATCA ACCCCATGGG ATGGGATGCT TTTGGATTGC CTGCTGAAAA TGCCGCAGTC 
GAGAGGAATC TACATCCACA AAGTTGGACA CAAAGTAATA TTAAACACAT GAGGAAACAG 
CTTGATCGTC TGGGCCTGTG TTTCAGCTGG GATAGGGAAA TAACTACGTG TTTGCCAGAT 
TACTACAAGT GGACTCAGTA TCTCTTTATT AAACTGTATG AGGCTGGGCT GGCCTATCAA 
AAGGAGGCCC TGGTTAACTG GGACCCAGTG GATCAAACAG TGCTTGCCAA TGAGCAGGTG 
GATGAACATG GCTGTTCATG GCGTTCTGGA GCAAAGGTGG AACAGAAGTA CCTCAGACAA 
TGGTTTATTA AGACAACCGC TTATGCAAAG GCCATGCAGG ACGCGTTGGC AGACCTTCCA 
GAATGGTATG GAATAAAAGG CATGCAAGCC CACTGGATTG GGGACTGTGT GGGCTGCCAC 
CTGGACTTCA CATTAAAGGT TCATGGGCAA GCCACGGGCG AAAAGCTGAC TGCCTATACG 
GCCACCCCTG AAGCCATTTA TGGCACCTCC CACGTGGCCA TCTCGCCCAG CCACAGACTC 
CTACATGGGC ACAGCTCTCT GAAGGAAGCC TTGAGGATGG CCCTTGTCCC TGGCAAAGAT 
TGCCTCACGC CTGTAATGGC TGTGAACATG CTTACCCAGC AGGAGGTCCC TGTCGTTATT 
TTGGCCAAAG CTGACTTGGA AGGCTCTCTG GATTCAAAAA TAGGAATTCC CAGTACTAGC 
TCAGAGGACA CCATCTTAGC CCAAACCCTG GGCCTGGCCT ACTCTGAAGT CATTGAAACT 
TTGCCAGATG GCACAGAGAG ACTGAGCAGC TCTGCTGAGT TCACAGGTAT GACCCGGCAG 
GATGCTTTTC TAGCCCTGAC TCAGAAAGCC CGGGGGAAGA GAGTGGGTGG AGACGTGACA 
AGTGATAAAC TGAAAGACTG GCTGATTTCA CGGCAGCGGT ACTGGGGCAC ACCAATCCCC 
ATTGTCCACT GCCCAGTCTG TGGCCCCACA CCTGTGCCCC TGGAGGACTT GCCTGTGACC 
CTGCCCAACA TCGCGTCTTT CACTGGCAAG GGAGGCCCCC CACTGGCCAT GGCTTCAGAG 
TGGGTGAACT GCTCCTGCCC AAGGTGCAAG GGAGCAGCCA AGAGAGAGAC AGACACGATG 
GATACCTTTG TTGATTCTGC TTGGTACTAC TTCAGATACA CTGACCCTCA TAATCCACAC 
AGCCCTTTTA ACACAGCAGT GGCCGATTAC TGGATGCCTG TGGATTTGTA CATTGGAGGG 
AAAGAACATG CCGTCATGCA CTTGTTCTAT GCAAGATTCT TTAGTCATTT TTGCCATGAT 
CAAAAAATGG TTAAACATAG GGAGCCTTTT CATAAGCTGC TGGCCCAAGG CCTTATCAAG 
GGGCAGACAT TCCGCCTACC ATCTGGACAG TATCTACAGA GAGAGGAAGT GGATCTCACA 
GGTTCCGTTC CTGTTCATGC AAAAACGAAA GAGAAGTTAG AGGTGACGTG GGAGAAGATG 
AGTAAGTCCA AACACAACGG GGTGGACCCA GAGGAAGTTG TGGAGCAGTA TGGGATCGAC 
ACGATTCGGC TCTACATCCT TTTTGCTGCC CCTCCTGAGA AGGATATCTT GTGGGATGTG 
AAAACTGATG CTCTCCCTGG GGTGCTGAGA TGGCAACAAC GACTGTGGAC CTTGACAACT 
CGGTTTATTG AGGCCAGGGC TTCTGGGAAG TCTCCCCAGC CTCAGCTGCT GAGTAACAAG 
GAGAAAGCTG AGGCCAGGAA GCTCTGGGAG TACAAGAACT CCGTCATCTC TCAGGTGACC 
ACCCATTTCA CAGAGGACTT CTCACTGAAT TCTGCAATTT CTCAGCTGAT GGGACTCAGC 
AATGCCCTCT CGCAAGCCTC TCAGAGCGTC ATTCTCCACA GCCCCGAGTT TGAGGATGCT 
TTGTGTGCCC TGATGGTAAT GGCTGCTCCA CTGGCCCCTC ATGTAACCTC AGAGATCTGG 
GCAGGCCTGG CGCTGGTGCC GAGGAAGCTC TGTGCCCACT ACACTTGGGA TGCCAGTGTG 
CTGCTCCAGG CATGGCCTGC TGTGGACCCG GAGTTCCTGC AGCAGCCTGA GGTTGTCCAG 
ATGGCAGTTC TGATCAACAA TAAAGCTTGT GGCAAAATTC CTGTGCCCCA ACAAGTTGCC 
CGGGACCAGG ACAAAGTCCA CGAATTTGTT CTTCAAAGCG AGCTGGGTGT CAGGCTTTTG 
CAAGGACGAA GCATCAAGAA GTCCTTCCTT TCCCCGAGAA CTGCCCTCAT CAACTTCCTG 
GTGCAAGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001355192.1
CDS	127..2838
Translation	MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVHGQATGEKLTAYTATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMALVPGKDCLTPVMAVNMLTQQEVPVVILAKADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPDGTERLSSSAEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMASEWVNCSCPRCKGAAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNKEKAEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDALCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQMAVLINNKACGKIPVPQQVARDQDKVHEFVLQSELGVRLLQGRSIKKSFLSPRTALINFLVQD

Target ORF information:

RefSeq Version	NM_001368263.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001368263.1

ORF Insert Sequence:

ATGGCTTCTG TTTGGCAGAG ATTGGGTTTT TATGCCTCTC TTCTGAAAAG ACAGCTAAAT 
GGTGGGCCAG ATGTCATCAA GTGGGAAAGG AGAGTAATTC CCGGATGTAC CAGAAGCATC 
TACAGTGCCA CGGGAAAGTG GACAAAAGAG TATACATTGC AGACAAGAAA GGATGTTGAG 
AAATGGTGGC ATCAACGAAT AAAAGAACAG GCCTCCAAAA TTTCAGAAGC TGATAAATCG 
AAGCCAAAAT TTTACGTGCT TTCCATGTTC CCTTATCCTT CTGGTAAGCT GCACATGGGC 
CATGTGCGTG TCTACACCAT CAGCGACACC ATAGCACGGT TCCAGAAGAT GAGAGGGATG 
CAGGTCATCA ACCCCATGGG ATGGGATGCT TTTGGATTGC CTGCTGAAAA TGCCGCAGTC 
GAGAGGAATC TACATCCACA AAGTTGGACA CAAAGTAATA TTAAACACAT GAGGAAACAG 
CTTGATCGTC TGGGCCTGTG TTTCAGCTGG GATAGGGAAA TAACTACGTG TTTGCCAGAT 
TACTACAAGT GGACTCAGTA TCTCTTTATT AAACTGTATG AGGCTGGGCT GGCCTATCAA 
AAGGAGGCCC TGGTTAACTG GGACCCAGTG GATCAAACAG TGCTTGCCAA TGAGCAGGTG 
GATGAACATG GCTGTTCATG GCGTTCTGGA GCAAAGGTGG AACAGAAGTA CCTCAGACAA 
TGGTTTATTA AGACAACCGC TTATGCAAAG GCCATGCAGG ACGCGTTGGC AGACCTTCCA 
GAATGGTATG GAATAAAAGG CATGCAAGCC CACTGGATTG GGGACTGTGT GGGCTGCCAC 
CTGGACTTCA CATTAAAGGT TCATGGGCAA GCCACGGGCG AAAAGCTGAC TGCCTATACG 
GCCACCCCTG AAGCCATTTA TGGCACCTCC CACGTGGCCA TCTCGCCCAG CCACAGACTC 
CTACATGGGC ACAGCTCTCT GAAGGAAGCC TTGAGGATGG CCCTTGTCCC TGGCAAAGAT 
TGCCTCACGC CTGTAATGGC TGTGAACATG CTTACCCAGC AGGAGGTCCC TGTCGTTATT 
TTGGCCAAAG CTGACTTGGA AGGCTCTCTG GATTCAAAAA TAGGAATTCC CAGTACTAGC 
TCAGAGGACA CCATCTTAGC CCAAACCCTG GGCCTGGCCT ACTCTGAAGT CATTGAAACT 
TTGCCAGATG GCACAGAGAG ACTGAGCAGC TCTGCTGAGT TCACAGGTAT GACCCGGCAG 
GATGCTTTTC TAGCCCTGAC TCAGAAAGCC CGGGGGAAGA GAGTGGGTGG AGACGTGACA 
AGTGATAAAC TGAAAGACTG GCTGATTTCA CGGCAGCGGT ACTGGGGCAC ACCAATCCCC 
ATTGTCCACT GCCCAGTCTG TGGCCCCACA CCTGTGCCCC TGGAGGACTT GCCTGTGACC 
CTGCCCAACA TCGCGTCTTT CACTGGCAAG GGAGGCCCCC CACTGGCCAT GGCTTCAGAG 
TGGGTGAACT GCTCCTGCCC AAGGTGCAAG GGAGCAGCCA AGAGAGAGAC AGACACGATG 
GATACCTTTG TTGATTCTGC TTGGTACTAC TTCAGATACA CTGACCCTCA TAATCCACAC 
AGCCCTTTTA ACACAGCAGT GGCCGATTAC TGGATGCCTG TGGATTTGTA CATTGGAGGG 
AAAGAACATG CCGTCATGCA CTTGTTCTAT GCAAGATTCT TTAGTCATTT TTGCCATGAT 
CAAAAAATGG TTAAACATAG GGAGCCTTTT CATAAGCTGC TGGCCCAAGG CCTTATCAAG 
GGGCAGACAT TCCGCCTACC ATCTGGACAG TATCTACAGA GAGAGGAAGT GGATCTCACA 
GGTTCCGTTC CTGTTCATGC AAAAACGAAA GAGAAGTTAG AGGTGACGTG GGAGAAGATG 
AGTAAGTCCA AACACAACGG GGTGGACCCA GAGGAAGTTG TGGAGCAGTA TGGGATCGAC 
ACGATTCGGC TCTACATCCT TTTTGCTGCC CCTCCTGAGA AGGATATCTT GTGGGATGTG 
AAAACTGATG CTCTCCCTGG GGTGCTGAGA TGGCAACAAC GACTGTGGAC CTTGACAACT 
CGGTTTATTG AGGCCAGGGC TTCTGGGAAG TCTCCCCAGC CTCAGCTGCT GAGTAACAAG 
GAGAAAGCTG AGGCCAGGAA GCTCTGGGAG TACAAGAACT CCGTCATCTC TCAGGTGACC 
ACCCATTTCA CAGAGGACTT CTCACTGAAT TCTGCAATTT CTCAGCTGAT GGGACTCAGC 
AATGCCCTCT CGCAAGCCTC TCAGAGCGTC ATTCTCCACA GCCCCGAGTT TGAGGATGCT 
TTGTGTGCCC TGATGGTAAT GGCTGCTCCA CTGGCCCCTC ATGTAACCTC AGAGATCTGG 
GCAGGCCTGG CGCTGGTGCC GAGGAAGCTC TGTGCCCACT ACACTTGGGA TGCCAGTGTG 
CTGCTCCAGG CATGGCCTGC TGTGGACCCG GAGTTCCTGC AGCAGCCTGA GGTTGTCCAG 
ATGGCAGTTC TGATCAACAA TAAAGCTTGT GGCAAAATTC CTGTGCCCCA ACAAGTTGCC 
CGGGACCAGG ACAAAGTCCA CGAATTTGTT CTTCAAAGCG AGCTGGGTGT CAGGCTTTTG 
CAAGGACGAA GCATCAAGAA GTCCTTCCTT TCCCCGAGAA CTGCCCTCAT CAACTTCCTG 
GTGCAAGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LARS2 ( XM_005265006.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005265063.1 Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu18528
Clone ID Related Accession (Same CDS sequence)	NM_015340.4 , NM_015340.3 , XM_005265006.1 , XM_005265006.2 , NM_001368263.1
Accession Version	XM_005265006.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2712bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	probable leucine--tRNA ligase, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCTG TTTGGCAGAG ATTGGGTTTT TATGCCTCTC TTCTGAAAAG ACAGCTAAAT 
GGTGGGCCAG ATGTCATCAA GTGGGAAAGG AGAGTAATTC CCGGATGTAC CAGAAGCATC 
TACAGTGCCA CGGGAAAGTG GACAAAAGAG TATACATTGC AGACAAGAAA GGATGTTGAG 
AAATGGTGGC ATCAACGAAT AAAAGAACAG GCCTCCAAAA TTTCAGAAGC TGATAAATCG 
AAGCCAAAAT TTTACGTGCT TTCCATGTTC CCTTATCCTT CTGGTAAGCT GCACATGGGC 
CATGTGCGTG TCTACACCAT CAGCGACACC ATAGCACGGT TCCAGAAGAT GAGAGGGATG 
CAGGTCATCA ACCCCATGGG ATGGGATGCT TTTGGATTGC CTGCTGAAAA TGCCGCAGTC 
GAGAGGAATC TACATCCACA AAGTTGGACA CAAAGTAATA TTAAACACAT GAGGAAACAG 
CTTGATCGTC TGGGCCTGTG TTTCAGCTGG GATAGGGAAA TAACTACGTG TTTGCCAGAT 
TACTACAAGT GGACTCAGTA TCTCTTTATT AAACTGTATG AGGCTGGGCT GGCCTATCAA 
AAGGAGGCCC TGGTTAACTG GGACCCAGTG GATCAAACAG TGCTTGCCAA TGAGCAGGTG 
GATGAACATG GCTGTTCATG GCGTTCTGGA GCAAAGGTGG AACAGAAGTA CCTCAGACAA 
TGGTTTATTA AGACAACCGC TTATGCAAAG GCCATGCAGG ACGCGTTGGC AGACCTTCCA 
GAATGGTATG GAATAAAAGG CATGCAAGCC CACTGGATTG GGGACTGTGT GGGCTGCCAC 
CTGGACTTCA CATTAAAGGT TCATGGGCAA GCCACGGGCG AAAAGCTGAC TGCCTATACG 
GCCACCCCTG AAGCCATTTA TGGCACCTCC CACGTGGCCA TCTCGCCCAG CCACAGACTC 
CTACATGGGC ACAGCTCTCT GAAGGAAGCC TTGAGGATGG CCCTTGTCCC TGGCAAAGAT 
TGCCTCACGC CTGTAATGGC TGTGAACATG CTTACCCAGC AGGAGGTCCC TGTCGTTATT 
TTGGCCAAAG CTGACTTGGA AGGCTCTCTG GATTCAAAAA TAGGAATTCC CAGTACTAGC 
TCAGAGGACA CCATCTTAGC CCAAACCCTG GGCCTGGCCT ACTCTGAAGT CATTGAAACT 
TTGCCAGATG GCACAGAGAG ACTGAGCAGC TCTGCTGAGT TCACAGGTAT GACCCGGCAG 
GATGCTTTTC TAGCCCTGAC TCAGAAAGCC CGGGGGAAGA GAGTGGGTGG AGACGTGACA 
AGTGATAAAC TGAAAGACTG GCTGATTTCA CGGCAGCGGT ACTGGGGCAC ACCAATCCCC 
ATTGTCCACT GCCCAGTCTG TGGCCCCACA CCTGTGCCCC TGGAGGACTT GCCTGTGACC 
CTGCCCAACA TCGCGTCTTT CACTGGCAAG GGAGGCCCCC CACTGGCCAT GGCTTCAGAG 
TGGGTGAACT GCTCCTGCCC AAGGTGCAAG GGAGCAGCCA AGAGAGAGAC AGACACGATG 
GATACCTTTG TTGATTCTGC TTGGTACTAC TTCAGATACA CTGACCCTCA TAATCCACAC 
AGCCCTTTTA ACACAGCAGT GGCCGATTAC TGGATGCCTG TGGATTTGTA CATTGGAGGG 
AAAGAACATG CCGTCATGCA CTTGTTCTAT GCAAGATTCT TTAGTCATTT TTGCCATGAT 
CAAAAAATGG TTAAACATAG GGAGCCTTTT CATAAGCTGC TGGCCCAAGG CCTTATCAAG 
GGGCAGACAT TCCGCCTACC ATCTGGACAG TATCTACAGA GAGAGGAAGT GGATCTCACA 
GGTTCCGTTC CTGTTCATGC AAAAACGAAA GAGAAGTTAG AGGTGACGTG GGAGAAGATG 
AGTAAGTCCA AACACAACGG GGTGGACCCA GAGGAAGTTG TGGAGCAGTA TGGGATCGAC 
ACGATTCGGC TCTACATCCT TTTTGCTGCC CCTCCTGAGA AGGATATCTT GTGGGATGTG 
AAAACTGATG CTCTCCCTGG GGTGCTGAGA TGGCAACAAC GACTGTGGAC CTTGACAACT 
CGGTTTATTG AGGCCAGGGC TTCTGGGAAG TCTCCCCAGC CTCAGCTGCT GAGTAACAAG 
GAGAAAGCTG AGGCCAGGAA GCTCTGGGAG TACAAGAACT CCGTCATCTC TCAGGTGACC 
ACCCATTTCA CAGAGGACTT CTCACTGAAT TCTGCAATTT CTCAGCTGAT GGGACTCAGC 
AATGCCCTCT CGCAAGCCTC TCAGAGCGTC ATTCTCCACA GCCCCGAGTT TGAGGATGCT 
TTGTGTGCCC TGATGGTAAT GGCTGCTCCA CTGGCCCCTC ATGTAACCTC AGAGATCTGG 
GCAGGCCTGG CGCTGGTGCC GAGGAAGCTC TGTGCCCACT ACACTTGGGA TGCCAGTGTG 
CTGCTCCAGG CATGGCCTGC TGTGGACCCG GAGTTCCTGC AGCAGCCTGA GGTTGTCCAG 
ATGGCAGTTC TGATCAACAA TAAAGCTTGT GGCAAAATTC CTGTGCCCCA ACAAGTTGCC 
CGGGACCAGG ACAAAGTCCA CGAATTTGTT CTTCAAAGCG AGCTGGGTGT CAGGCTTTTG 
CAAGGACGAA GCATCAAGAA GTCCTTCCTT TCCCCGAGAA CTGCCCTCAT CAACTTCCTG 
GTGCAAGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005265063.1
CDS	142..2853
Translation	MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVHGQATGEKLTAYTATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMALVPGKDCLTPVMAVNMLTQQEVPVVILAKADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPDGTERLSSSAEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMASEWVNCSCPRCKGAAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNKEKAEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDALCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQMAVLINNKACGKIPVPQQVARDQDKVHEFVLQSELGVRLLQGRSIKKSFLSPRTALINFLVQD

Target ORF information:

RefSeq Version	XM_005265006.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005265006.1

ORF Insert Sequence:

ATGGCTTCTG TTTGGCAGAG ATTGGGTTTT TATGCCTCTC TTCTGAAAAG ACAGCTAAAT 
GGTGGGCCAG ATGTCATCAA GTGGGAAAGG AGAGTAATTC CCGGATGTAC CAGAAGCATC 
TACAGTGCCA CGGGAAAGTG GACAAAAGAG TATACATTGC AGACAAGAAA GGATGTTGAG 
AAATGGTGGC ATCAACGAAT AAAAGAACAG GCCTCCAAAA TTTCAGAAGC TGATAAATCG 
AAGCCAAAAT TTTACGTGCT TTCCATGTTC CCTTATCCTT CTGGTAAGCT GCACATGGGC 
CATGTGCGTG TCTACACCAT CAGCGACACC ATAGCACGGT TCCAGAAGAT GAGAGGGATG 
CAGGTCATCA ACCCCATGGG ATGGGATGCT TTTGGATTGC CTGCTGAAAA TGCCGCAGTC 
GAGAGGAATC TACATCCACA AAGTTGGACA CAAAGTAATA TTAAACACAT GAGGAAACAG 
CTTGATCGTC TGGGCCTGTG TTTCAGCTGG GATAGGGAAA TAACTACGTG TTTGCCAGAT 
TACTACAAGT GGACTCAGTA TCTCTTTATT AAACTGTATG AGGCTGGGCT GGCCTATCAA 
AAGGAGGCCC TGGTTAACTG GGACCCAGTG GATCAAACAG TGCTTGCCAA TGAGCAGGTG 
GATGAACATG GCTGTTCATG GCGTTCTGGA GCAAAGGTGG AACAGAAGTA CCTCAGACAA 
TGGTTTATTA AGACAACCGC TTATGCAAAG GCCATGCAGG ACGCGTTGGC AGACCTTCCA 
GAATGGTATG GAATAAAAGG CATGCAAGCC CACTGGATTG GGGACTGTGT GGGCTGCCAC 
CTGGACTTCA CATTAAAGGT TCATGGGCAA GCCACGGGCG AAAAGCTGAC TGCCTATACG 
GCCACCCCTG AAGCCATTTA TGGCACCTCC CACGTGGCCA TCTCGCCCAG CCACAGACTC 
CTACATGGGC ACAGCTCTCT GAAGGAAGCC TTGAGGATGG CCCTTGTCCC TGGCAAAGAT 
TGCCTCACGC CTGTAATGGC TGTGAACATG CTTACCCAGC AGGAGGTCCC TGTCGTTATT 
TTGGCCAAAG CTGACTTGGA AGGCTCTCTG GATTCAAAAA TAGGAATTCC CAGTACTAGC 
TCAGAGGACA CCATCTTAGC CCAAACCCTG GGCCTGGCCT ACTCTGAAGT CATTGAAACT 
TTGCCAGATG GCACAGAGAG ACTGAGCAGC TCTGCTGAGT TCACAGGTAT GACCCGGCAG 
GATGCTTTTC TAGCCCTGAC TCAGAAAGCC CGGGGGAAGA GAGTGGGTGG AGACGTGACA 
AGTGATAAAC TGAAAGACTG GCTGATTTCA CGGCAGCGGT ACTGGGGCAC ACCAATCCCC 
ATTGTCCACT GCCCAGTCTG TGGCCCCACA CCTGTGCCCC TGGAGGACTT GCCTGTGACC 
CTGCCCAACA TCGCGTCTTT CACTGGCAAG GGAGGCCCCC CACTGGCCAT GGCTTCAGAG 
TGGGTGAACT GCTCCTGCCC AAGGTGCAAG GGAGCAGCCA AGAGAGAGAC AGACACGATG 
GATACCTTTG TTGATTCTGC TTGGTACTAC TTCAGATACA CTGACCCTCA TAATCCACAC 
AGCCCTTTTA ACACAGCAGT GGCCGATTAC TGGATGCCTG TGGATTTGTA CATTGGAGGG 
AAAGAACATG CCGTCATGCA CTTGTTCTAT GCAAGATTCT TTAGTCATTT TTGCCATGAT 
CAAAAAATGG TTAAACATAG GGAGCCTTTT CATAAGCTGC TGGCCCAAGG CCTTATCAAG 
GGGCAGACAT TCCGCCTACC ATCTGGACAG TATCTACAGA GAGAGGAAGT GGATCTCACA 
GGTTCCGTTC CTGTTCATGC AAAAACGAAA GAGAAGTTAG AGGTGACGTG GGAGAAGATG 
AGTAAGTCCA AACACAACGG GGTGGACCCA GAGGAAGTTG TGGAGCAGTA TGGGATCGAC 
ACGATTCGGC TCTACATCCT TTTTGCTGCC CCTCCTGAGA AGGATATCTT GTGGGATGTG 
AAAACTGATG CTCTCCCTGG GGTGCTGAGA TGGCAACAAC GACTGTGGAC CTTGACAACT 
CGGTTTATTG AGGCCAGGGC TTCTGGGAAG TCTCCCCAGC CTCAGCTGCT GAGTAACAAG 
GAGAAAGCTG AGGCCAGGAA GCTCTGGGAG TACAAGAACT CCGTCATCTC TCAGGTGACC 
ACCCATTTCA CAGAGGACTT CTCACTGAAT TCTGCAATTT CTCAGCTGAT GGGACTCAGC 
AATGCCCTCT CGCAAGCCTC TCAGAGCGTC ATTCTCCACA GCCCCGAGTT TGAGGATGCT 
TTGTGTGCCC TGATGGTAAT GGCTGCTCCA CTGGCCCCTC ATGTAACCTC AGAGATCTGG 
GCAGGCCTGG CGCTGGTGCC GAGGAAGCTC TGTGCCCACT ACACTTGGGA TGCCAGTGTG 
CTGCTCCAGG CATGGCCTGC TGTGGACCCG GAGTTCCTGC AGCAGCCTGA GGTTGTCCAG 
ATGGCAGTTC TGATCAACAA TAAAGCTTGT GGCAAAATTC CTGTGCCCCA ACAAGTTGCC 
CGGGACCAGG ACAAAGTCCA CGAATTTGTT CTTCAAAGCG AGCTGGGTGT CAGGCTTTTG 
CAAGGACGAA GCATCAAGAA GTCCTTCCTT TCCCCGAGAA CTGCCCTCAT CAACTTCCTG 
GTGCAAGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LARS2 ( XM_005265006.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005265063.1 Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), transcript variant X1, mRNA.

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CloneID	OHu18528
Clone ID Related Accession (Same CDS sequence)	NM_015340.4 , NM_015340.3 , XM_005265006.1 , XM_005265006.2 , NM_001368263.1
Accession Version	XM_005265006.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2712bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	probable leucine--tRNA ligase, mitochondrial isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005265006.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCTG TTTGGCAGAG ATTGGGTTTT TATGCCTCTC TTCTGAAAAG ACAGCTAAAT 
GGTGGGCCAG ATGTCATCAA GTGGGAAAGG AGAGTAATTC CCGGATGTAC CAGAAGCATC 
TACAGTGCCA CGGGAAAGTG GACAAAAGAG TATACATTGC AGACAAGAAA GGATGTTGAG 
AAATGGTGGC ATCAACGAAT AAAAGAACAG GCCTCCAAAA TTTCAGAAGC TGATAAATCG 
AAGCCAAAAT TTTACGTGCT TTCCATGTTC CCTTATCCTT CTGGTAAGCT GCACATGGGC 
CATGTGCGTG TCTACACCAT CAGCGACACC ATAGCACGGT TCCAGAAGAT GAGAGGGATG 
CAGGTCATCA ACCCCATGGG ATGGGATGCT TTTGGATTGC CTGCTGAAAA TGCCGCAGTC 
GAGAGGAATC TACATCCACA AAGTTGGACA CAAAGTAATA TTAAACACAT GAGGAAACAG 
CTTGATCGTC TGGGCCTGTG TTTCAGCTGG GATAGGGAAA TAACTACGTG TTTGCCAGAT 
TACTACAAGT GGACTCAGTA TCTCTTTATT AAACTGTATG AGGCTGGGCT GGCCTATCAA 
AAGGAGGCCC TGGTTAACTG GGACCCAGTG GATCAAACAG TGCTTGCCAA TGAGCAGGTG 
GATGAACATG GCTGTTCATG GCGTTCTGGA GCAAAGGTGG AACAGAAGTA CCTCAGACAA 
TGGTTTATTA AGACAACCGC TTATGCAAAG GCCATGCAGG ACGCGTTGGC AGACCTTCCA 
GAATGGTATG GAATAAAAGG CATGCAAGCC CACTGGATTG GGGACTGTGT GGGCTGCCAC 
CTGGACTTCA CATTAAAGGT TCATGGGCAA GCCACGGGCG AAAAGCTGAC TGCCTATACG 
GCCACCCCTG AAGCCATTTA TGGCACCTCC CACGTGGCCA TCTCGCCCAG CCACAGACTC 
CTACATGGGC ACAGCTCTCT GAAGGAAGCC TTGAGGATGG CCCTTGTCCC TGGCAAAGAT 
TGCCTCACGC CTGTAATGGC TGTGAACATG CTTACCCAGC AGGAGGTCCC TGTCGTTATT 
TTGGCCAAAG CTGACTTGGA AGGCTCTCTG GATTCAAAAA TAGGAATTCC CAGTACTAGC 
TCAGAGGACA CCATCTTAGC CCAAACCCTG GGCCTGGCCT ACTCTGAAGT CATTGAAACT 
TTGCCAGATG GCACAGAGAG ACTGAGCAGC TCTGCTGAGT TCACAGGTAT GACCCGGCAG 
GATGCTTTTC TAGCCCTGAC TCAGAAAGCC CGGGGGAAGA GAGTGGGTGG AGACGTGACA 
AGTGATAAAC TGAAAGACTG GCTGATTTCA CGGCAGCGGT ACTGGGGCAC ACCAATCCCC 
ATTGTCCACT GCCCAGTCTG TGGCCCCACA CCTGTGCCCC TGGAGGACTT GCCTGTGACC 
CTGCCCAACA TCGCGTCTTT CACTGGCAAG GGAGGCCCCC CACTGGCCAT GGCTTCAGAG 
TGGGTGAACT GCTCCTGCCC AAGGTGCAAG GGAGCAGCCA AGAGAGAGAC AGACACGATG 
GATACCTTTG TTGATTCTGC TTGGTACTAC TTCAGATACA CTGACCCTCA TAATCCACAC 
AGCCCTTTTA ACACAGCAGT GGCCGATTAC TGGATGCCTG TGGATTTGTA CATTGGAGGG 
AAAGAACATG CCGTCATGCA CTTGTTCTAT GCAAGATTCT TTAGTCATTT TTGCCATGAT 
CAAAAAATGG TTAAACATAG GGAGCCTTTT CATAAGCTGC TGGCCCAAGG CCTTATCAAG 
GGGCAGACAT TCCGCCTACC ATCTGGACAG TATCTACAGA GAGAGGAAGT GGATCTCACA 
GGTTCCGTTC CTGTTCATGC AAAAACGAAA GAGAAGTTAG AGGTGACGTG GGAGAAGATG 
AGTAAGTCCA AACACAACGG GGTGGACCCA GAGGAAGTTG TGGAGCAGTA TGGGATCGAC 
ACGATTCGGC TCTACATCCT TTTTGCTGCC CCTCCTGAGA AGGATATCTT GTGGGATGTG 
AAAACTGATG CTCTCCCTGG GGTGCTGAGA TGGCAACAAC GACTGTGGAC CTTGACAACT 
CGGTTTATTG AGGCCAGGGC TTCTGGGAAG TCTCCCCAGC CTCAGCTGCT GAGTAACAAG 
GAGAAAGCTG AGGCCAGGAA GCTCTGGGAG TACAAGAACT CCGTCATCTC TCAGGTGACC 
ACCCATTTCA CAGAGGACTT CTCACTGAAT TCTGCAATTT CTCAGCTGAT GGGACTCAGC 
AATGCCCTCT CGCAAGCCTC TCAGAGCGTC ATTCTCCACA GCCCCGAGTT TGAGGATGCT 
TTGTGTGCCC TGATGGTAAT GGCTGCTCCA CTGGCCCCTC ATGTAACCTC AGAGATCTGG 
GCAGGCCTGG CGCTGGTGCC GAGGAAGCTC TGTGCCCACT ACACTTGGGA TGCCAGTGTG 
CTGCTCCAGG CATGGCCTGC TGTGGACCCG GAGTTCCTGC AGCAGCCTGA GGTTGTCCAG 
ATGGCAGTTC TGATCAACAA TAAAGCTTGT GGCAAAATTC CTGTGCCCCA ACAAGTTGCC 
CGGGACCAGG ACAAAGTCCA CGAATTTGTT CTTCAAAGCG AGCTGGGTGT CAGGCTTTTG 
CAAGGACGAA GCATCAAGAA GTCCTTCCTT TCCCCGAGAA CTGCCCTCAT CAACTTCCTG 
GTGCAAGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005265063.1
CDS	139..2850
Translation	MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVHGQATGEKLTAYTATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMALVPGKDCLTPVMAVNMLTQQEVPVVILAKADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPDGTERLSSSAEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMASEWVNCSCPRCKGAAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNKEKAEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDALCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQMAVLINNKACGKIPVPQQVARDQDKVHEFVLQSELGVRLLQGRSIKKSFLSPRTALINFLVQD

Target ORF information:

RefSeq Version	XM_005265006.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005265006.2

ORF Insert Sequence:

ATGGCTTCTG TTTGGCAGAG ATTGGGTTTT TATGCCTCTC TTCTGAAAAG ACAGCTAAAT 
GGTGGGCCAG ATGTCATCAA GTGGGAAAGG AGAGTAATTC CCGGATGTAC CAGAAGCATC 
TACAGTGCCA CGGGAAAGTG GACAAAAGAG TATACATTGC AGACAAGAAA GGATGTTGAG 
AAATGGTGGC ATCAACGAAT AAAAGAACAG GCCTCCAAAA TTTCAGAAGC TGATAAATCG 
AAGCCAAAAT TTTACGTGCT TTCCATGTTC CCTTATCCTT CTGGTAAGCT GCACATGGGC 
CATGTGCGTG TCTACACCAT CAGCGACACC ATAGCACGGT TCCAGAAGAT GAGAGGGATG 
CAGGTCATCA ACCCCATGGG ATGGGATGCT TTTGGATTGC CTGCTGAAAA TGCCGCAGTC 
GAGAGGAATC TACATCCACA AAGTTGGACA CAAAGTAATA TTAAACACAT GAGGAAACAG 
CTTGATCGTC TGGGCCTGTG TTTCAGCTGG GATAGGGAAA TAACTACGTG TTTGCCAGAT 
TACTACAAGT GGACTCAGTA TCTCTTTATT AAACTGTATG AGGCTGGGCT GGCCTATCAA 
AAGGAGGCCC TGGTTAACTG GGACCCAGTG GATCAAACAG TGCTTGCCAA TGAGCAGGTG 
GATGAACATG GCTGTTCATG GCGTTCTGGA GCAAAGGTGG AACAGAAGTA CCTCAGACAA 
TGGTTTATTA AGACAACCGC TTATGCAAAG GCCATGCAGG ACGCGTTGGC AGACCTTCCA 
GAATGGTATG GAATAAAAGG CATGCAAGCC CACTGGATTG GGGACTGTGT GGGCTGCCAC 
CTGGACTTCA CATTAAAGGT TCATGGGCAA GCCACGGGCG AAAAGCTGAC TGCCTATACG 
GCCACCCCTG AAGCCATTTA TGGCACCTCC CACGTGGCCA TCTCGCCCAG CCACAGACTC 
CTACATGGGC ACAGCTCTCT GAAGGAAGCC TTGAGGATGG CCCTTGTCCC TGGCAAAGAT 
TGCCTCACGC CTGTAATGGC TGTGAACATG CTTACCCAGC AGGAGGTCCC TGTCGTTATT 
TTGGCCAAAG CTGACTTGGA AGGCTCTCTG GATTCAAAAA TAGGAATTCC CAGTACTAGC 
TCAGAGGACA CCATCTTAGC CCAAACCCTG GGCCTGGCCT ACTCTGAAGT CATTGAAACT 
TTGCCAGATG GCACAGAGAG ACTGAGCAGC TCTGCTGAGT TCACAGGTAT GACCCGGCAG 
GATGCTTTTC TAGCCCTGAC TCAGAAAGCC CGGGGGAAGA GAGTGGGTGG AGACGTGACA 
AGTGATAAAC TGAAAGACTG GCTGATTTCA CGGCAGCGGT ACTGGGGCAC ACCAATCCCC 
ATTGTCCACT GCCCAGTCTG TGGCCCCACA CCTGTGCCCC TGGAGGACTT GCCTGTGACC 
CTGCCCAACA TCGCGTCTTT CACTGGCAAG GGAGGCCCCC CACTGGCCAT GGCTTCAGAG 
TGGGTGAACT GCTCCTGCCC AAGGTGCAAG GGAGCAGCCA AGAGAGAGAC AGACACGATG 
GATACCTTTG TTGATTCTGC TTGGTACTAC TTCAGATACA CTGACCCTCA TAATCCACAC 
AGCCCTTTTA ACACAGCAGT GGCCGATTAC TGGATGCCTG TGGATTTGTA CATTGGAGGG 
AAAGAACATG CCGTCATGCA CTTGTTCTAT GCAAGATTCT TTAGTCATTT TTGCCATGAT 
CAAAAAATGG TTAAACATAG GGAGCCTTTT CATAAGCTGC TGGCCCAAGG CCTTATCAAG 
GGGCAGACAT TCCGCCTACC ATCTGGACAG TATCTACAGA GAGAGGAAGT GGATCTCACA 
GGTTCCGTTC CTGTTCATGC AAAAACGAAA GAGAAGTTAG AGGTGACGTG GGAGAAGATG 
AGTAAGTCCA AACACAACGG GGTGGACCCA GAGGAAGTTG TGGAGCAGTA TGGGATCGAC 
ACGATTCGGC TCTACATCCT TTTTGCTGCC CCTCCTGAGA AGGATATCTT GTGGGATGTG 
AAAACTGATG CTCTCCCTGG GGTGCTGAGA TGGCAACAAC GACTGTGGAC CTTGACAACT 
CGGTTTATTG AGGCCAGGGC TTCTGGGAAG TCTCCCCAGC CTCAGCTGCT GAGTAACAAG 
GAGAAAGCTG AGGCCAGGAA GCTCTGGGAG TACAAGAACT CCGTCATCTC TCAGGTGACC 
ACCCATTTCA CAGAGGACTT CTCACTGAAT TCTGCAATTT CTCAGCTGAT GGGACTCAGC 
AATGCCCTCT CGCAAGCCTC TCAGAGCGTC ATTCTCCACA GCCCCGAGTT TGAGGATGCT 
TTGTGTGCCC TGATGGTAAT GGCTGCTCCA CTGGCCCCTC ATGTAACCTC AGAGATCTGG 
GCAGGCCTGG CGCTGGTGCC GAGGAAGCTC TGTGCCCACT ACACTTGGGA TGCCAGTGTG 
CTGCTCCAGG CATGGCCTGC TGTGGACCCG GAGTTCCTGC AGCAGCCTGA GGTTGTCCAG 
ATGGCAGTTC TGATCAACAA TAAAGCTTGT GGCAAAATTC CTGTGCCCCA ACAAGTTGCC 
CGGGACCAGG ACAAAGTCCA CGAATTTGTT CTTCAAAGCG AGCTGGGTGT CAGGCTTTTG 
CAAGGACGAA GCATCAAGAA GTCCTTCCTT TCCCCGAGAA CTGCCCTCAT CAACTTCCTG 
GTGCAAGATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LARS2 ( XM_011533554.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011531856.1 Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), transcript variant X2, mRNA.

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CloneID	OHu66139
Clone ID Related Accession (Same CDS sequence)	XM_011533554.2
Accession Version	XM_011533554.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2493bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	probable leucine--tRNA ligase, mitochondrial isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011533554.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCTG TTTGGCAGAG ATTGGGTTTT TATGCCTCTC TTCTGAAAAG ACAGCTAAAT 
GGTGGGCCAG ATGTCATCAA GTGGGAAAGG AGAGTAATTC CCGGATGTAC CAGAAGCATC 
TACAGTGCCA CGGGAAAGTG GACAAAAGAG TATACATTGC AGACAAGAAA GGATGTTGAG 
AAATGGTGGC ATCAACGAAT AAAAGAACAG GCCTCCAAAA TTTCAGAAGC TGATAAATCG 
AAGCCAAAAT TTTACGTGCT TTCCATGTTC CCTTATCCTT CTGGTAAGCT GCACATGGGC 
CATGTGCGTG TCTACACCAT CAGCGACACC ATAGCACGGT TCCAGAAGAT GAGAGGGATG 
CAGGTCATCA ACCCCATGGG ATGGGATGCT TTTGGATTGC CTGCTGAAAA TGCCGCAGTC 
GAGAGGAATC TACATCCACA AAGTTGGACA CAAAGTAATA TTAAACACAT GAGGAAACAG 
CTTGATCGTC TGGGCCTGTG TTTCAGCTGG GATAGGGAAA TAACTACGTG TTTGCCAGAT 
TACTACAAGT GGACTCAGTA TCTCTTTATT AAACTGTATG AGGCTGGGCT GGCCTATCAA 
AAGGAGGCCC TGGTTAACTG GGACCCAGTG GATCAAACAG TGCTTGCCAA TGAGCAGGTG 
GATGAACATG GCTGTTCATG GCGTTCTGGA GCAAAGGTGG AACAGAAGTA CCTCAGACAA 
TGGTTTATTA AGACAACCGC TTATGCAAAG GCCATGCAGG ACGCGTTGGC AGACCTTCCA 
GAATGGTATG GAATAAAAGG CATGCAAGCC CACTGGATTG GGGACTGTGT GGGCTGCCAC 
CTGGACTTCA CATTAAAGGT TCATGGGCAA GCCACGGGCG AAAAGCTGAC TGCCTATACG 
GCCACCCCTG AAGCCATTTA TGGCACCTCC CACGTGGCCA TCTCGCCCAG CCACAGACTC 
CTACATGGGC ACAGCTCTCT GAAGGAAGCC TTGAGGATGG CCCTTGTCCC TGGCAAAGAT 
TGCCTCACGC CTGTAATGGC TGTGAACATG CTTACCCAGC AGGAGGTCCC TGTCGTTATT 
TTGGCCAAAG CTGACTTGGA AGGCTCTCTG GATTCAAAAA TAGGAATTCC CAGTACTAGC 
TCAGAGGACA CCATCTTAGC CCAAACCCTG GGCCTGGCCT ACTCTGAAGT CATTGAAACT 
TTGCCAGATG GCACAGAGAG ACTGAGCAGC TCTGCTGAGT TCACAGGTAT GACCCGGCAG 
GATGCTTTTC TAGCCCTGAC TCAGAAAGCC CGGGGGAAGA GAGTGGGTGG AGACGTGACA 
AGTGATAAAC TGAAAGACTG GCTGATTTCA CGGCAGCGGT ACTGGGGCAC ACCAATCCCC 
ATTGTCCACT GCCCAGTCTG TGGCCCCACA CCTGTGCCCC TGGAGGACTT GCCTGTGACC 
CTGCCCAACA TCGCGTCTTT CACTGGCAAG GGAGGCCCCC CACTGGCCAT GGCTTCAGAG 
TGGGTGAACT GCTCCTGCCC AAGGTGCAAG GGAGCAGCCA AGAGAGAGAC AGACACGATG 
GATACCTTTG TTGATTCTGC TTGGTACTAC TTCAGATACA CTGACCCTCA TAATCCACAC 
AGCCCTTTTA ACACAGCAGT GGCCGATTAC TGGATGCCTG TGGATTTGTA CATTGGAGGG 
AAAGAACATG CCGTCATGCA CTTGTTCTAT GCAAGATTCT TTAGTCATTT TTGCCATGAT 
CAAAAAATGG TTAAACATAG GGAGCCTTTT CATAAGCTGC TGGCCCAAGG CCTTATCAAG 
GGGCAGACAT TCCGCCTACC ATCTGGACAG TATCTACAGA GAGAGGAAGT GGATCTCACA 
GGTTCCGTTC CTGTTCATGC AAAAACGAAA GAGAAGTTAG AGGTGACGTG GGAGAAGATG 
AGTAAGTCCA AACACAACGG GGTGGACCCA GAGGAAGTTG TGGAGCAGTA TGGGATCGAC 
ACGATTCGGC TCTACATCCT TTTTGCTGCC CCTCCTGAGA AGGATATCTT GTGGGATGTG 
AAAACTGATG CTCTCCCTGG GGTGCTGAGA TGGCAACAAC GACTGTGGAC CTTGACAACT 
CGGTTTATTG AGGCCAGGGC TTCTGGGAAG TCTCCCCAGC CTCAGCTGCT GAGTAACAAG 
GAGAAAGCTG AGGCCAGGAA GCTCTGGGAG TACAAGAACT CCGTCATCTC TCAGGTGACC 
ACCCATTTCA CAGAGGACTT CTCACTGAAT TCTGCAATTT CTCAGCTGAT GGGACTCAGC 
AATGCCCTCT CGCAAGCCTC TCAGAGCGTC ATTCTCCACA GCCCCGAGTT TGAGGATGCT 
TTGTGTGCCC TGATGGTAAT GGCTGCTCCA CTGGCCCCTC ATGTAACCTC AGAGATCTGG 
GCAGGCATCC TGTACAACTG CCATACGGAG GTTTTGGAAA TCTTCCCGCT GCAGCTGGGT 
CACAGGACAA GCCACACAGG ACCAGCTCAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011531856.1
CDS	205..2697
Translation	MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVHGQATGEKLTAYTATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMALVPGKDCLTPVMAVNMLTQQEVPVVILAKADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPDGTERLSSSAEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMASEWVNCSCPRCKGAAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNKEKAEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDALCALMVMAAPLAPHVTSEIWAGILYNCHTEVLEIFPLQLGHRTSHTGPAH

Target ORF information:

RefSeq Version	XM_011533554.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011533554.2

ORF Insert Sequence:

ATGGCTTCTG TTTGGCAGAG ATTGGGTTTT TATGCCTCTC TTCTGAAAAG ACAGCTAAAT 
GGTGGGCCAG ATGTCATCAA GTGGGAAAGG AGAGTAATTC CCGGATGTAC CAGAAGCATC 
TACAGTGCCA CGGGAAAGTG GACAAAAGAG TATACATTGC AGACAAGAAA GGATGTTGAG 
AAATGGTGGC ATCAACGAAT AAAAGAACAG GCCTCCAAAA TTTCAGAAGC TGATAAATCG 
AAGCCAAAAT TTTACGTGCT TTCCATGTTC CCTTATCCTT CTGGTAAGCT GCACATGGGC 
CATGTGCGTG TCTACACCAT CAGCGACACC ATAGCACGGT TCCAGAAGAT GAGAGGGATG 
CAGGTCATCA ACCCCATGGG ATGGGATGCT TTTGGATTGC CTGCTGAAAA TGCCGCAGTC 
GAGAGGAATC TACATCCACA AAGTTGGACA CAAAGTAATA TTAAACACAT GAGGAAACAG 
CTTGATCGTC TGGGCCTGTG TTTCAGCTGG GATAGGGAAA TAACTACGTG TTTGCCAGAT 
TACTACAAGT GGACTCAGTA TCTCTTTATT AAACTGTATG AGGCTGGGCT GGCCTATCAA 
AAGGAGGCCC TGGTTAACTG GGACCCAGTG GATCAAACAG TGCTTGCCAA TGAGCAGGTG 
GATGAACATG GCTGTTCATG GCGTTCTGGA GCAAAGGTGG AACAGAAGTA CCTCAGACAA 
TGGTTTATTA AGACAACCGC TTATGCAAAG GCCATGCAGG ACGCGTTGGC AGACCTTCCA 
GAATGGTATG GAATAAAAGG CATGCAAGCC CACTGGATTG GGGACTGTGT GGGCTGCCAC 
CTGGACTTCA CATTAAAGGT TCATGGGCAA GCCACGGGCG AAAAGCTGAC TGCCTATACG 
GCCACCCCTG AAGCCATTTA TGGCACCTCC CACGTGGCCA TCTCGCCCAG CCACAGACTC 
CTACATGGGC ACAGCTCTCT GAAGGAAGCC TTGAGGATGG CCCTTGTCCC TGGCAAAGAT 
TGCCTCACGC CTGTAATGGC TGTGAACATG CTTACCCAGC AGGAGGTCCC TGTCGTTATT 
TTGGCCAAAG CTGACTTGGA AGGCTCTCTG GATTCAAAAA TAGGAATTCC CAGTACTAGC 
TCAGAGGACA CCATCTTAGC CCAAACCCTG GGCCTGGCCT ACTCTGAAGT CATTGAAACT 
TTGCCAGATG GCACAGAGAG ACTGAGCAGC TCTGCTGAGT TCACAGGTAT GACCCGGCAG 
GATGCTTTTC TAGCCCTGAC TCAGAAAGCC CGGGGGAAGA GAGTGGGTGG AGACGTGACA 
AGTGATAAAC TGAAAGACTG GCTGATTTCA CGGCAGCGGT ACTGGGGCAC ACCAATCCCC 
ATTGTCCACT GCCCAGTCTG TGGCCCCACA CCTGTGCCCC TGGAGGACTT GCCTGTGACC 
CTGCCCAACA TCGCGTCTTT CACTGGCAAG GGAGGCCCCC CACTGGCCAT GGCTTCAGAG 
TGGGTGAACT GCTCCTGCCC AAGGTGCAAG GGAGCAGCCA AGAGAGAGAC AGACACGATG 
GATACCTTTG TTGATTCTGC TTGGTACTAC TTCAGATACA CTGACCCTCA TAATCCACAC 
AGCCCTTTTA ACACAGCAGT GGCCGATTAC TGGATGCCTG TGGATTTGTA CATTGGAGGG 
AAAGAACATG CCGTCATGCA CTTGTTCTAT GCAAGATTCT TTAGTCATTT TTGCCATGAT 
CAAAAAATGG TTAAACATAG GGAGCCTTTT CATAAGCTGC TGGCCCAAGG CCTTATCAAG 
GGGCAGACAT TCCGCCTACC ATCTGGACAG TATCTACAGA GAGAGGAAGT GGATCTCACA 
GGTTCCGTTC CTGTTCATGC AAAAACGAAA GAGAAGTTAG AGGTGACGTG GGAGAAGATG 
AGTAAGTCCA AACACAACGG GGTGGACCCA GAGGAAGTTG TGGAGCAGTA TGGGATCGAC 
ACGATTCGGC TCTACATCCT TTTTGCTGCC CCTCCTGAGA AGGATATCTT GTGGGATGTG 
AAAACTGATG CTCTCCCTGG GGTGCTGAGA TGGCAACAAC GACTGTGGAC CTTGACAACT 
CGGTTTATTG AGGCCAGGGC TTCTGGGAAG TCTCCCCAGC CTCAGCTGCT GAGTAACAAG 
GAGAAAGCTG AGGCCAGGAA GCTCTGGGAG TACAAGAACT CCGTCATCTC TCAGGTGACC 
ACCCATTTCA CAGAGGACTT CTCACTGAAT TCTGCAATTT CTCAGCTGAT GGGACTCAGC 
AATGCCCTCT CGCAAGCCTC TCAGAGCGTC ATTCTCCACA GCCCCGAGTT TGAGGATGCT 
TTGTGTGCCC TGATGGTAAT GGCTGCTCCA CTGGCCCCTC ATGTAACCTC AGAGATCTGG 
GCAGGCATCC TGTACAACTG CCATACGGAG GTTTTGGAAA TCTTCCCGCT GCAGCTGGGT 
CACAGGACAA GCCACACAGG ACCAGCTCAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LARS2 ( XM_017006042.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016861531.1 Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), transcript variant X3, mRNA.

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CloneID	OHu93991
Clone ID Related Accession (Same CDS sequence)	XM_017006042.1
Accession Version	XM_017006042.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2415bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	probable leucine--tRNA ligase, mitochondrial isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTTCTG TTTGGCAGAG ATTGGGTTTT TATGCCTCTC TTCTGAAAAG ACAGCTAAAT 
GGTGGGCCAG ATGTCATCAA GTGGGAAAGG AGAGTAATTC CCGGATGTAC CAGAAGCATC 
TACAGTGCCA CGGGAAAGTG GACAAAAGAG TATACATTGC AGACAAGAAA GGATGTTGAG 
AAATGGTGGC ATCAACGAAT AAAAGAACAG GCCTCCAAAA TTTCAGAAGC TGATAAATCG 
AAGCCAAAAT TTTACGTGCT TTCCATGTTC CCTTATCCTT CTGGTAAGCT GCACATGGGC 
CATGTGCGTG TCTACACCAT CAGCGACACC ATAGCACGGT TCCAGAAGAT GAGAGGGATG 
CAGGTCATCA ACCCCATGGG ATGGGATGCT TTTGGATTGC CTGCTGAAAA TGCCGCAGTC 
GAGAGGAATC TACATCCACA AAGTTGGACA CAAAGTAATA TTAAACACAT GAGGAAACAG 
CTTGATCGTC TGGGCCTGTG TTTCAGCTGG GATAGGGAAA TAACTACGTG TTTGCCAGAT 
TACTACAAGT GGACTCAGTA TCTCTTTATT AAACTGTATG AGGCTGGGCT GGCCTATCAA 
AAGGAGGCCC TGGTTAACTG GGACCCAGTG GATCAAACAG TGCTTGCCAA TGAGCAGGTG 
GATGAACATG GCTGTTCATG GCGTTCTGGA GCAAAGGTGG AACAGAAGTA CCTCAGACAA 
TGGTTTATTA AGACAACCGC TTATGCAAAG GCCATGCAGG ACGCGTTGGC AGACCTTCCA 
GAATGGTATG GAATAAAAGG CATGCAAGCC CACTGGATTG GGGACTGTGT GGGCTGCCAC 
CTGGACTTCA CATTAAAGGT TCATGGGCAA GCCACGGGCG AAAAGCTGAC TGCCTATACG 
GCCACCCCTG AAGCCATTTA TGGCACCTCC CACGTGGCCA TCTCGCCCAG CCACAGACTC 
CTACATGGGC ACAGCTCTCT GAAGGAAGCC TTGAGGATGG CCCTTGTCCC TGGCAAAGAT 
TGCCTCACGC CTGTAATGGC TGTGAACATG CTTACCCAGC AGGAGGTCCC TGTCGTTATT 
TTGGCCAAAG CTGACTTGGA AGGCTCTCTG GATTCAAAAA TAGGAATTCC CAGTACTAGC 
TCAGAGGACA CCATCTTAGC CCAAACCCTG GGCCTGGCCT ACTCTGAAGT CATTGAAACT 
TTGCCAGATG GCACAGAGAG ACTGAGCAGC TCTGCTGAGT TCACAGGTAT GACCCGGCAG 
GATGCTTTTC TAGCCCTGAC TCAGAAAGCC CGGGGGAAGA GAGTGGGTGG AGACGTGACA 
AGTGATAAAC TGAAAGACTG GCTGATTTCA CGGCAGCGGT ACTGGGGCAC ACCAATCCCC 
ATTGTCCACT GCCCAGTCTG TGGCCCCACA CCTGTGCCCC TGGAGGACTT GCCTGTGACC 
CTGCCCAACA TCGCGTCTTT CACTGGCAAG GGAGGCCCCC CACTGGCCAT GGCTTCAGAG 
TGGGTGAACT GCTCCTGCCC AAGGTGCAAG GGAGCAGCCA AGAGAGAGAC AGACACGATG 
GATACCTTTG TTGATTCTGC TTGGTACTAC TTCAGATACA CTGACCCTCA TAATCCACAC 
AGCCCTTTTA ACACAGCAGT GGCCGATTAC TGGATGCCTG TGGATTTGTA CATTGGAGGG 
AAAGAACATG CCGTCATGCA CTTGTTCTAT GCAAGATTCT TTAGTCATTT TTGCCATGAT 
CAAAAAATGG TTAAACATAG GGAGCCTTTT CATAAGCTGC TGGCCCAAGG CCTTATCAAG 
GGGCAGACAT TCCGCCTACC ATCTGGACAG TATCTACAGA GAGAGGAAGT GGATCTCACA 
GGTTCCGTTC CTGTTCATGC AAAAACGAAA GAGAAGTTAG AGGTGACGTG GGAGAAGATG 
AGTAAGTCCA AACACAACGG GGTGGACCCA GAGGAAGTTG TGGAGCAGTA TGGGATCGAC 
ACGATTCGGC TCTACATCCT TTTTGCTGCC CCTCCTGAGA AGGATATCTT GTGGGATGTG 
AAAACTGATG CTCTCCCTGG GGTGCTGAGA TGGCAACAAC GACTGTGGAC CTTGACAACT 
CGGTTTATTG AGGCCAGGGC TTCTGGGAAG TCTCCCCAGC CTCAGCTGCT GAGTAACAAG 
GAGAAAGCTG AGGCCAGGAA GCTCTGGGAG TACAAGAACT CCGTCATCTC TCAGGTGACC 
ACCCATTTCA CAGAGGACTT CTCACTGAAT TCTGCAATTT CTCAGCTGAT GGGACTCAGC 
AATGCCCTCT CGCAAGCCTC TCAGAGCGTC ATTCTCCACA GCCCCGAGTT TGAGGATGCT 
TTGTGTGCCC TGATGGTAAT GGCTGCTCCA CTGGCCCCTC ATGTAACCTC AGAGATCTGG 
GCAGATCAAC AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016861531.1
CDS	205..2619
Translation	MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSATGKWTKEYTLQTRKDVEKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQWFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVHGQATGEKLTAYTATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMALVPGKDCLTPVMAVNMLTQQEVPVVILAKADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPDGTERLSSSAEFTGMTRQDAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVTLPNIASFTGKGGPPLAMASEWVNCSCPRCKGAAKRETDTMDTFVDSAWYYFRYTDPHNPHSPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIKGQTFRLPSGQYLQREEVDLTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGIDTIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNKEKAEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDALCALMVMAAPLAPHVTSEIWADQQ

Target ORF information:

RefSeq Version	XM_017006042.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucyl-tRNA synthetase 2, mitochondrial (LARS2), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017006042.1

ORF Insert Sequence:

ATGGCTTCTG TTTGGCAGAG ATTGGGTTTT TATGCCTCTC TTCTGAAAAG ACAGCTAAAT 
GGTGGGCCAG ATGTCATCAA GTGGGAAAGG AGAGTAATTC CCGGATGTAC CAGAAGCATC 
TACAGTGCCA CGGGAAAGTG GACAAAAGAG TATACATTGC AGACAAGAAA GGATGTTGAG 
AAATGGTGGC ATCAACGAAT AAAAGAACAG GCCTCCAAAA TTTCAGAAGC TGATAAATCG 
AAGCCAAAAT TTTACGTGCT TTCCATGTTC CCTTATCCTT CTGGTAAGCT GCACATGGGC 
CATGTGCGTG TCTACACCAT CAGCGACACC ATAGCACGGT TCCAGAAGAT GAGAGGGATG 
CAGGTCATCA ACCCCATGGG ATGGGATGCT TTTGGATTGC CTGCTGAAAA TGCCGCAGTC 
GAGAGGAATC TACATCCACA AAGTTGGACA CAAAGTAATA TTAAACACAT GAGGAAACAG 
CTTGATCGTC TGGGCCTGTG TTTCAGCTGG GATAGGGAAA TAACTACGTG TTTGCCAGAT 
TACTACAAGT GGACTCAGTA TCTCTTTATT AAACTGTATG AGGCTGGGCT GGCCTATCAA 
AAGGAGGCCC TGGTTAACTG GGACCCAGTG GATCAAACAG TGCTTGCCAA TGAGCAGGTG 
GATGAACATG GCTGTTCATG GCGTTCTGGA GCAAAGGTGG AACAGAAGTA CCTCAGACAA 
TGGTTTATTA AGACAACCGC TTATGCAAAG GCCATGCAGG ACGCGTTGGC AGACCTTCCA 
GAATGGTATG GAATAAAAGG CATGCAAGCC CACTGGATTG GGGACTGTGT GGGCTGCCAC 
CTGGACTTCA CATTAAAGGT TCATGGGCAA GCCACGGGCG AAAAGCTGAC TGCCTATACG 
GCCACCCCTG AAGCCATTTA TGGCACCTCC CACGTGGCCA TCTCGCCCAG CCACAGACTC 
CTACATGGGC ACAGCTCTCT GAAGGAAGCC TTGAGGATGG CCCTTGTCCC TGGCAAAGAT 
TGCCTCACGC CTGTAATGGC TGTGAACATG CTTACCCAGC AGGAGGTCCC TGTCGTTATT 
TTGGCCAAAG CTGACTTGGA AGGCTCTCTG GATTCAAAAA TAGGAATTCC CAGTACTAGC 
TCAGAGGACA CCATCTTAGC CCAAACCCTG GGCCTGGCCT ACTCTGAAGT CATTGAAACT 
TTGCCAGATG GCACAGAGAG ACTGAGCAGC TCTGCTGAGT TCACAGGTAT GACCCGGCAG 
GATGCTTTTC TAGCCCTGAC TCAGAAAGCC CGGGGGAAGA GAGTGGGTGG AGACGTGACA 
AGTGATAAAC TGAAAGACTG GCTGATTTCA CGGCAGCGGT ACTGGGGCAC ACCAATCCCC 
ATTGTCCACT GCCCAGTCTG TGGCCCCACA CCTGTGCCCC TGGAGGACTT GCCTGTGACC 
CTGCCCAACA TCGCGTCTTT CACTGGCAAG GGAGGCCCCC CACTGGCCAT GGCTTCAGAG 
TGGGTGAACT GCTCCTGCCC AAGGTGCAAG GGAGCAGCCA AGAGAGAGAC AGACACGATG 
GATACCTTTG TTGATTCTGC TTGGTACTAC TTCAGATACA CTGACCCTCA TAATCCACAC 
AGCCCTTTTA ACACAGCAGT GGCCGATTAC TGGATGCCTG TGGATTTGTA CATTGGAGGG 
AAAGAACATG CCGTCATGCA CTTGTTCTAT GCAAGATTCT TTAGTCATTT TTGCCATGAT 
CAAAAAATGG TTAAACATAG GGAGCCTTTT CATAAGCTGC TGGCCCAAGG CCTTATCAAG 
GGGCAGACAT TCCGCCTACC ATCTGGACAG TATCTACAGA GAGAGGAAGT GGATCTCACA 
GGTTCCGTTC CTGTTCATGC AAAAACGAAA GAGAAGTTAG AGGTGACGTG GGAGAAGATG 
AGTAAGTCCA AACACAACGG GGTGGACCCA GAGGAAGTTG TGGAGCAGTA TGGGATCGAC 
ACGATTCGGC TCTACATCCT TTTTGCTGCC CCTCCTGAGA AGGATATCTT GTGGGATGTG 
AAAACTGATG CTCTCCCTGG GGTGCTGAGA TGGCAACAAC GACTGTGGAC CTTGACAACT 
CGGTTTATTG AGGCCAGGGC TTCTGGGAAG TCTCCCCAGC CTCAGCTGCT GAGTAACAAG 
GAGAAAGCTG AGGCCAGGAA GCTCTGGGAG TACAAGAACT CCGTCATCTC TCAGGTGACC 
ACCCATTTCA CAGAGGACTT CTCACTGAAT TCTGCAATTT CTCAGCTGAT GGGACTCAGC 
AATGCCCTCT CGCAAGCCTC TCAGAGCGTC ATTCTCCACA GCCCCGAGTT TGAGGATGCT 
TTGTGTGCCC TGATGGTAAT GGCTGCTCCA CTGGCCCCTC ATGTAACCTC AGAGATCTGG 
GCAGATCAAC AATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Biallelic mutations in LARS2 can cause Perrault syndrome type 2 with neurologic symptoms.
American journal of medical genetics. Part A176(2)404-408(2018 Feb)
Kosaki R,Horikawa R,Fujii E,Kosaki K

Knockdown of IARS2 suppressed growth of gastric cancer cells by regulating the phosphorylation of cell cycle-related proteins.
Molecular and cellular biochemistry(2017 Oct)
Fang Z,Wang X,Yan Q,Zhang S,Li Y

Expanding the genotypic spectrum of Perrault syndrome.
Clinical genetics91(2)302-312(2017 Feb)
Demain LA,Urquhart JE,O'Sullivan J,Williams SG,Bhaskar SS,Jenkinson EM,Lourenco CM,Heiberg A,Pearce SH,Shalev SA,Yue WW,Mackinnon S,Munro KJ,Newbury-Ecob R,Becker K,Kim MJ,O' Keefe RT,Newman WG

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LARS2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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