NCSTN gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
XM_005245053.4	XP_005245110.1	nicastrin isoform X2
NM_015331.2	NP_056146.1	nicastrin isoform 1 precursor
NM_001349729.1	NP_001336658.1	nicastrin isoform 4 precursor
NM_001290184.2	NP_001277113.1	nicastrin isoform 2
NM_001290186.2	NP_001277115.1	nicastrin isoform 3 precursor
NM_001290186.1	NP_001277115.1	nicastrin isoform 3 precursor
NM_015331.3	NP_056146.1	nicastrin isoform 1 precursor
NM_001290184.1	NP_001277113.1	nicastrin isoform 2
NM_001349729.2	NP_001336658.1	nicastrin isoform 4 precursor
XM_005245053.5	XP_005245110.1	nicastrin isoform X1

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23623	NM_015331.3 Latest version!	Homo sapiens nicastrin (NCSTN), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$354.50-$496.30 $709.00
OHu08810	NM_001290186.2 Latest version!	Homo sapiens nicastrin (NCSTN), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu66123	NM_001349729.2 Latest version!	Homo sapiens nicastrin (NCSTN), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu34278	XM_005245053.5 Latest version!	Homo sapiens nicastrin (NCSTN), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu08813	NM_001290184.2 Latest version!	Homo sapiens nicastrin (NCSTN), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
View Old Accession Versions >>
OHu08810	NM_001290186.1	Homo sapiens nicastrin (NCSTN), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu23623	NM_015331.2	Homo sapiens nicastrin (NCSTN), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$354.50-$496.30 $709.00
OHu08813	NM_001290184.1	Homo sapiens nicastrin (NCSTN), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu66123	NM_001349729.1	Homo sapiens nicastrin (NCSTN), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu34278	XM_005245053.4	Homo sapiens nicastrin (NCSTN), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

NCSTN ( NM_015331.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_056146.1 Homo sapiens nicastrin (NCSTN), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23623
Clone ID Related Accession (Same CDS sequence)	NM_015331.2 , NM_015331.3
Accession Version	NM_015331.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2130bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-15
Organism	Homo sapiens(human)
Product	nicastrin isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF240468.1, BC047621.1 and CN429672.1. This sequence is a reference standard in the RefSeqGene project. On Apr 14, 2005 this sequence version replaced NM_015331.1. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.58775.1, AF240468.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTACGG CAGGGGGTGG CTCTGGGGCT GACCCGGGAA GTCGGGGTCT CCTTCGCCTT 
CTGTCTTTCT GCGTCCTACT AGCAGGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGTGCTATCA AGATCACAAC 
CTGAGTCAGA ATGGCTCAGC ACCAACCTTC CCACTATGTG CCATGCAGCT CTTTTCACAC 
ATGCATGCTG TCATCAGCAC TGCCACCTGC ATGCGGCGCA GCTCCATCCA AAGCACCTTC 
AGCATCAACC CAGAAATCGT CTGTGACCCC CTGTCTGATT ACAATGTGTG GAGCATGCTA 
AAGCCTATAA ATACAACTGG GACATTAAAG CCTGACGACA GGGTTGTGGT TGCTGCCACC 
CGGCTGGATA GTCGTTCCTT TTTCTGGAAT GTGGCCCCAG GGGCTGAAAG CGCAGTGGCT 
TCCTTTGTCA CCCAGCTGGC TGCTGCTGAA GCTTTGCAAA AGGCACCTGA TGTGACCACC 
CTGCCCCGCA ATGTCATGTT TGTCTTCTTT CAAGGGGAAA CTTTTGACTA CATTGGCAGC 
TCGAGGATGG TCTACGATAT GGAGAAGGGC AAGTTTCCCG TGCAGTTAGA GAATGTTGAC 
TCATTTGTGG AGCTGGGACA GGTGGCCTTA AGAACTTCAT TAGAGCTTTG GATGCACACA 
GATCCTGTTT CTCAGAAAAA TGAGTCTGTA CGGAACCAGG TGGAGGATCT CCTGGCCACA 
TTGGAGAAGA GTGGTGCTGG TGTCCCTGCT GTCATCCTCA GGAGGCCAAA TCAGTCCCAG 
CCTCTCCCAC CATCTTCCCT GCAGCGATTT CTTCGAGCTC GAAACATCTC TGGCGTTGTT 
CTGGCTGACC ACTCTGGTGC CTTCCATAAC AAATATTACC AGAGTATTTA CGACACTGCT 
GAGAACATTA ATGTGAGCTA TCCCGAATGG CTGAGCCCTG AAGAGGACCT GAACTTTGTA 
ACAGACACTG CCAAGGCCCT GGCAGATGTG GCCACGGTGC TGGGACGTGC TCTGTATGAG 
CTTGCAGGAG GAACCAACTT CAGCGACACA GTTCAGGCTG ATCCCCAAAC GGTTACCCGC 
CTGCTCTATG GGTTCCTGAT TAAAGCCAAC AACTCATGGT TCCAGTCTAT CCTCAGGCAG 
GACCTAAGGT CCTACTTGGG TGACGGGCCT CTTCAACATT ACATCGCTGT CTCCAGCCCC 
ACCAACACCA CTTATGTTGT ACAGTATGCC TTGGCAAATT TGACTGGCAC AGTGGTCAAC 
CTCACCCGAG AGCAGTGCCA GGATCCAAGT AAAGTCCCAA GTGAAAACAA GGATCTGTAT 
GAGTACTCAT GGGTCCAGGG CCCTTTGCAT TCTAATGAGA CGGACCGACT CCCCCGGTGT 
GTGCGTTCTA CTGCACGATT AGCCAGGGCC TTGTCTCCTG CCTTTGAACT GAGTCAGTGG 
AGCTCTACTG AATACTCTAC ATGGACTGAG AGCCGCTGGA AAGATATCCG TGCCCGGATA 
TTTCTCATCG CCAGCAAAGA GCTTGAGTTG ATCACCCTGA CAGTGGGCTT CGGCATCCTC 
ATCTTCTCCC TCATCGTCAC CTACTGCATC AATGCCAAAG CTGATGTCCT TTTCATTGCT 
CCCCGGGAGC CAGGAGCTGT GTCATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056146.1
CDS	125..2254
Translation	MATAGGGSGADPGSRGLLRLLSFCVLLAGLCRGNSVERKIYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSPSVQCPNDGFGVYSNSYGPEFAHCREIQWNSLGNGLAYEDFSFPIFLLEDENETKVIKQCYQDHNLSQNGSAPTFPLCAMQLFSHMHAVISTATCMRRSSIQSTFSINPEIVCDPLSDYNVWSMLKPINTTGTLKPDDRVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEALQKAPDVTTLPRNVMFVFFQGETFDYIGSSRMVYDMEKGKFPVQLENVDSFVELGQVALRTSLELWMHTDPVSQKNESVRNQVEDLLATLEKSGAGVPAVILRRPNQSQPLPPSSLQRFLRARNISGVVLADHSGAFHNKYYQSIYDTAENINVSYPEWLSPEEDLNFVTDTAKALADVATVLGRALYELAGGTNFSDTVQADPQTVTRLLYGFLIKANNSWFQSILRQDLRSYLGDGPLQHYIAVSSPTNTTYVVQYALANLTGTVVNLTREQCQDPSKVPSENKDLYEYSWVQGPLHSNETDRLPRCVRSTARLARALSPAFELSQWSSTEYSTWTESRWKDIRARIFLIASKELELITLTVGFGILIFSLIVTYCINAKADVLFIAPREPGAVSY

Target ORF information:

RefSeq Version	NM_015331.2
Organism	Homo sapiens(human)
Definition	Homo sapiens nicastrin (NCSTN), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015331.2

ORF Insert Sequence:

ATGGCTACGG CAGGGGGTGG CTCTGGGGCT GACCCGGGAA GTCGGGGTCT CCTTCGCCTT 
CTGTCTTTCT GCGTCCTACT AGCAGGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGTGCTATCA AGATCACAAC 
CTGAGTCAGA ATGGCTCAGC ACCAACCTTC CCACTATGTG CCATGCAGCT CTTTTCACAC 
ATGCATGCTG TCATCAGCAC TGCCACCTGC ATGCGGCGCA GCTCCATCCA AAGCACCTTC 
AGCATCAACC CAGAAATCGT CTGTGACCCC CTGTCTGATT ACAATGTGTG GAGCATGCTA 
AAGCCTATAA ATACAACTGG GACATTAAAG CCTGACGACA GGGTTGTGGT TGCTGCCACC 
CGGCTGGATA GTCGTTCCTT TTTCTGGAAT GTGGCCCCAG GGGCTGAAAG CGCAGTGGCT 
TCCTTTGTCA CCCAGCTGGC TGCTGCTGAA GCTTTGCAAA AGGCACCTGA TGTGACCACC 
CTGCCCCGCA ATGTCATGTT TGTCTTCTTT CAAGGGGAAA CTTTTGACTA CATTGGCAGC 
TCGAGGATGG TCTACGATAT GGAGAAGGGC AAGTTTCCCG TGCAGTTAGA GAATGTTGAC 
TCATTTGTGG AGCTGGGACA GGTGGCCTTA AGAACTTCAT TAGAGCTTTG GATGCACACA 
GATCCTGTTT CTCAGAAAAA TGAGTCTGTA CGGAACCAGG TGGAGGATCT CCTGGCCACA 
TTGGAGAAGA GTGGTGCTGG TGTCCCTGCT GTCATCCTCA GGAGGCCAAA TCAGTCCCAG 
CCTCTCCCAC CATCTTCCCT GCAGCGATTT CTTCGAGCTC GAAACATCTC TGGCGTTGTT 
CTGGCTGACC ACTCTGGTGC CTTCCATAAC AAATATTACC AGAGTATTTA CGACACTGCT 
GAGAACATTA ATGTGAGCTA TCCCGAATGG CTGAGCCCTG AAGAGGACCT GAACTTTGTA 
ACAGACACTG CCAAGGCCCT GGCAGATGTG GCCACGGTGC TGGGACGTGC TCTGTATGAG 
CTTGCAGGAG GAACCAACTT CAGCGACACA GTTCAGGCTG ATCCCCAAAC GGTTACCCGC 
CTGCTCTATG GGTTCCTGAT TAAAGCCAAC AACTCATGGT TCCAGTCTAT CCTCAGGCAG 
GACCTAAGGT CCTACTTGGG TGACGGGCCT CTTCAACATT ACATCGCTGT CTCCAGCCCC 
ACCAACACCA CTTATGTTGT ACAGTATGCC TTGGCAAATT TGACTGGCAC AGTGGTCAAC 
CTCACCCGAG AGCAGTGCCA GGATCCAAGT AAAGTCCCAA GTGAAAACAA GGATCTGTAT 
GAGTACTCAT GGGTCCAGGG CCCTTTGCAT TCTAATGAGA CGGACCGACT CCCCCGGTGT 
GTGCGTTCTA CTGCACGATT AGCCAGGGCC TTGTCTCCTG CCTTTGAACT GAGTCAGTGG 
AGCTCTACTG AATACTCTAC ATGGACTGAG AGCCGCTGGA AAGATATCCG TGCCCGGATA 
TTTCTCATCG CCAGCAAAGA GCTTGAGTTG ATCACCCTGA CAGTGGGCTT CGGCATCCTC 
ATCTTCTCCC TCATCGTCAC CTACTGCATC AATGCCAAAG CTGATGTCCT TTTCATTGCT 
CCCCGGGAGC CAGGAGCTGT GTCATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NCSTN ( NM_015331.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_056146.1 Homo sapiens nicastrin (NCSTN), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23623
Clone ID Related Accession (Same CDS sequence)	NM_015331.2 , NM_015331.3
Accession Version	NM_015331.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2130bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	nicastrin isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF240468.1, BC047621.1 and CN429672.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_015331.2. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.580341.1, AF240468.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000294785.10/ ENSP00000294785.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTACGG CAGGGGGTGG CTCTGGGGCT GACCCGGGAA GTCGGGGTCT CCTTCGCCTT 
CTGTCTTTCT GCGTCCTACT AGCAGGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGTGCTATCA AGATCACAAC 
CTGAGTCAGA ATGGCTCAGC ACCAACCTTC CCACTATGTG CCATGCAGCT CTTTTCACAC 
ATGCATGCTG TCATCAGCAC TGCCACCTGC ATGCGGCGCA GCTCCATCCA AAGCACCTTC 
AGCATCAACC CAGAAATCGT CTGTGACCCC CTGTCTGATT ACAATGTGTG GAGCATGCTA 
AAGCCTATAA ATACAACTGG GACATTAAAG CCTGACGACA GGGTTGTGGT TGCTGCCACC 
CGGCTGGATA GTCGTTCCTT TTTCTGGAAT GTGGCCCCAG GGGCTGAAAG CGCAGTGGCT 
TCCTTTGTCA CCCAGCTGGC TGCTGCTGAA GCTTTGCAAA AGGCACCTGA TGTGACCACC 
CTGCCCCGCA ATGTCATGTT TGTCTTCTTT CAAGGGGAAA CTTTTGACTA CATTGGCAGC 
TCGAGGATGG TCTACGATAT GGAGAAGGGC AAGTTTCCCG TGCAGTTAGA GAATGTTGAC 
TCATTTGTGG AGCTGGGACA GGTGGCCTTA AGAACTTCAT TAGAGCTTTG GATGCACACA 
GATCCTGTTT CTCAGAAAAA TGAGTCTGTA CGGAACCAGG TGGAGGATCT CCTGGCCACA 
TTGGAGAAGA GTGGTGCTGG TGTCCCTGCT GTCATCCTCA GGAGGCCAAA TCAGTCCCAG 
CCTCTCCCAC CATCTTCCCT GCAGCGATTT CTTCGAGCTC GAAACATCTC TGGCGTTGTT 
CTGGCTGACC ACTCTGGTGC CTTCCATAAC AAATATTACC AGAGTATTTA CGACACTGCT 
GAGAACATTA ATGTGAGCTA TCCCGAATGG CTGAGCCCTG AAGAGGACCT GAACTTTGTA 
ACAGACACTG CCAAGGCCCT GGCAGATGTG GCCACGGTGC TGGGACGTGC TCTGTATGAG 
CTTGCAGGAG GAACCAACTT CAGCGACACA GTTCAGGCTG ATCCCCAAAC GGTTACCCGC 
CTGCTCTATG GGTTCCTGAT TAAAGCCAAC AACTCATGGT TCCAGTCTAT CCTCAGGCAG 
GACCTAAGGT CCTACTTGGG TGACGGGCCT CTTCAACATT ACATCGCTGT CTCCAGCCCC 
ACCAACACCA CTTATGTTGT ACAGTATGCC TTGGCAAATT TGACTGGCAC AGTGGTCAAC 
CTCACCCGAG AGCAGTGCCA GGATCCAAGT AAAGTCCCAA GTGAAAACAA GGATCTGTAT 
GAGTACTCAT GGGTCCAGGG CCCTTTGCAT TCTAATGAGA CGGACCGACT CCCCCGGTGT 
GTGCGTTCTA CTGCACGATT AGCCAGGGCC TTGTCTCCTG CCTTTGAACT GAGTCAGTGG 
AGCTCTACTG AATACTCTAC ATGGACTGAG AGCCGCTGGA AAGATATCCG TGCCCGGATA 
TTTCTCATCG CCAGCAAAGA GCTTGAGTTG ATCACCCTGA CAGTGGGCTT CGGCATCCTC 
ATCTTCTCCC TCATCGTCAC CTACTGCATC AATGCCAAAG CTGATGTCCT TTTCATTGCT 
CCCCGGGAGC CAGGAGCTGT GTCATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056146.1
CDS	15..2144
Translation	MATAGGGSGADPGSRGLLRLLSFCVLLAGLCRGNSVERKIYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSPSVQCPNDGFGVYSNSYGPEFAHCREIQWNSLGNGLAYEDFSFPIFLLEDENETKVIKQCYQDHNLSQNGSAPTFPLCAMQLFSHMHAVISTATCMRRSSIQSTFSINPEIVCDPLSDYNVWSMLKPINTTGTLKPDDRVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEALQKAPDVTTLPRNVMFVFFQGETFDYIGSSRMVYDMEKGKFPVQLENVDSFVELGQVALRTSLELWMHTDPVSQKNESVRNQVEDLLATLEKSGAGVPAVILRRPNQSQPLPPSSLQRFLRARNISGVVLADHSGAFHNKYYQSIYDTAENINVSYPEWLSPEEDLNFVTDTAKALADVATVLGRALYELAGGTNFSDTVQADPQTVTRLLYGFLIKANNSWFQSILRQDLRSYLGDGPLQHYIAVSSPTNTTYVVQYALANLTGTVVNLTREQCQDPSKVPSENKDLYEYSWVQGPLHSNETDRLPRCVRSTARLARALSPAFELSQWSSTEYSTWTESRWKDIRARIFLIASKELELITLTVGFGILIFSLIVTYCINAKADVLFIAPREPGAVSY

Target ORF information:

RefSeq Version	NM_015331.3
Organism	Homo sapiens(human)
Definition	Homo sapiens nicastrin (NCSTN), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015331.3

ORF Insert Sequence:

ATGGCTACGG CAGGGGGTGG CTCTGGGGCT GACCCGGGAA GTCGGGGTCT CCTTCGCCTT 
CTGTCTTTCT GCGTCCTACT AGCAGGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGTGCTATCA AGATCACAAC 
CTGAGTCAGA ATGGCTCAGC ACCAACCTTC CCACTATGTG CCATGCAGCT CTTTTCACAC 
ATGCATGCTG TCATCAGCAC TGCCACCTGC ATGCGGCGCA GCTCCATCCA AAGCACCTTC 
AGCATCAACC CAGAAATCGT CTGTGACCCC CTGTCTGATT ACAATGTGTG GAGCATGCTA 
AAGCCTATAA ATACAACTGG GACATTAAAG CCTGACGACA GGGTTGTGGT TGCTGCCACC 
CGGCTGGATA GTCGTTCCTT TTTCTGGAAT GTGGCCCCAG GGGCTGAAAG CGCAGTGGCT 
TCCTTTGTCA CCCAGCTGGC TGCTGCTGAA GCTTTGCAAA AGGCACCTGA TGTGACCACC 
CTGCCCCGCA ATGTCATGTT TGTCTTCTTT CAAGGGGAAA CTTTTGACTA CATTGGCAGC 
TCGAGGATGG TCTACGATAT GGAGAAGGGC AAGTTTCCCG TGCAGTTAGA GAATGTTGAC 
TCATTTGTGG AGCTGGGACA GGTGGCCTTA AGAACTTCAT TAGAGCTTTG GATGCACACA 
GATCCTGTTT CTCAGAAAAA TGAGTCTGTA CGGAACCAGG TGGAGGATCT CCTGGCCACA 
TTGGAGAAGA GTGGTGCTGG TGTCCCTGCT GTCATCCTCA GGAGGCCAAA TCAGTCCCAG 
CCTCTCCCAC CATCTTCCCT GCAGCGATTT CTTCGAGCTC GAAACATCTC TGGCGTTGTT 
CTGGCTGACC ACTCTGGTGC CTTCCATAAC AAATATTACC AGAGTATTTA CGACACTGCT 
GAGAACATTA ATGTGAGCTA TCCCGAATGG CTGAGCCCTG AAGAGGACCT GAACTTTGTA 
ACAGACACTG CCAAGGCCCT GGCAGATGTG GCCACGGTGC TGGGACGTGC TCTGTATGAG 
CTTGCAGGAG GAACCAACTT CAGCGACACA GTTCAGGCTG ATCCCCAAAC GGTTACCCGC 
CTGCTCTATG GGTTCCTGAT TAAAGCCAAC AACTCATGGT TCCAGTCTAT CCTCAGGCAG 
GACCTAAGGT CCTACTTGGG TGACGGGCCT CTTCAACATT ACATCGCTGT CTCCAGCCCC 
ACCAACACCA CTTATGTTGT ACAGTATGCC TTGGCAAATT TGACTGGCAC AGTGGTCAAC 
CTCACCCGAG AGCAGTGCCA GGATCCAAGT AAAGTCCCAA GTGAAAACAA GGATCTGTAT 
GAGTACTCAT GGGTCCAGGG CCCTTTGCAT TCTAATGAGA CGGACCGACT CCCCCGGTGT 
GTGCGTTCTA CTGCACGATT AGCCAGGGCC TTGTCTCCTG CCTTTGAACT GAGTCAGTGG 
AGCTCTACTG AATACTCTAC ATGGACTGAG AGCCGCTGGA AAGATATCCG TGCCCGGATA 
TTTCTCATCG CCAGCAAAGA GCTTGAGTTG ATCACCCTGA CAGTGGGCTT CGGCATCCTC 
ATCTTCTCCC TCATCGTCAC CTACTGCATC AATGCCAAAG CTGATGTCCT TTTCATTGCT 
CCCCGGGAGC CAGGAGCTGT GTCATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NCSTN ( NM_001290186.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001277115.1 Homo sapiens nicastrin (NCSTN), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu08810
Clone ID Related Accession (Same CDS sequence)	NM_001290186.2 , NM_001290186.1
Accession Version	NM_001290186.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1716bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	nicastrin isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF240468.1, AK299142.1, AL445230.11 and CN429672.1. On May 31, 2019 this sequence version replaced NM_001290186.1. Transcript Variant: This variant (3) lacks three alternate in-frame exons in the coding region compared to variant 1. The encoded isoform (3) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.918758.1, SRR1660805.11658.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTACGG CAGGGGGTGG CTCTGGGGCT GACCCGGGAA GTCGGGGTCT CCTTCGCCTT 
CTGTCTTTCT GCGTCCTACT AGCAGGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGGAAACTTT TGACTACATT 
GGCAGCTCGA GGATGGTCTA CGATATGGAG AAGGGCAAGT TTCCCGTGCA GTTAGAGAAT 
GTTGACTCAT TTGTGGAGCT GGGACAGGTG GCCTTAAGAA CTTCATTAGA GCTTTGGATG 
CACACAGATC CTGTTTCTCA GAAAAATGAG TCTGTACGGA ACCAGGTGGA GGATCTCCTG 
GCCACATTGG AGAAGAGTGG TGCTGGTGTC CCTGCTGTCA TCCTCAGGAG GCCAAATCAG 
TCCCAGCCTC TCCCACCATC TTCCCTGCAG CGATTTCTTC GAGCTCGAAA CATCTCTGGC 
GTTGTTCTGG CTGACCACTC TGGTGCCTTC CATAACAAAT ATTACCAGAG TATTTACGAC 
ACTGCTGAGA ACATTAATGT GAGCTATCCC GAATGGCTGA GCCCTGAAGA GGACCTGAAC 
TTTGTAACAG ACACTGCCAA GGCCCTGGCA GATGTGGCCA CGGTGCTGGG ACGTGCTCTG 
TATGAGCTTG CAGGAGGAAC CAACTTCAGC GACACAGTTC AGGCTGATCC CCAAACGGTT 
ACCCGCCTGC TCTATGGGTT CCTGATTAAA GCCAACAACT CATGGTTCCA GTCTATCCTC 
AGGCAGGACC TAAGGTCCTA CTTGGGTGAC GGGCCTCTTC AACATTACAT CGCTGTCTCC 
AGCCCCACCA ACACCACTTA TGTTGTACAG TATGCCTTGG CAAATTTGAC TGGCACAGTG 
GTCAACCTCA CCCGAGAGCA GTGCCAGGAT CCAAGTAAAG TCCCAAGTGA AAACAAGGAT 
CTGTATGAGT ACTCATGGGT CCAGGGCCCT TTGCATTCTA ATGAGACGGA CCGACTCCCC 
CGGTGTGTGC GTTCTACTGC ACGATTAGCC AGGGCCTTGT CTCCTGCCTT TGAACTGAGT 
CAGTGGAGCT CTACTGAATA CTCTACATGG ACTGAGAGCC GCTGGAAAGA TATCCGTGCC 
CGGATATTTC TCATCGCCAG CAAAGAGCTT GAGTTGATCA CCCTGACAGT GGGCTTCGGC 
ATCCTCATCT TCTCCCTCAT CGTCACCTAC TGCATCAATG CCAAAGCTGA TGTCCTTTTC 
ATTGCTCCCC GGGAGCCAGG AGCTGTGTCA TACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001277115.1
CDS	15..1730
Translation	MATAGGGSGADPGSRGLLRLLSFCVLLAGLCRGNSVERKIYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSPSVQCPNDGFGVYSNSYGPEFAHCREIQWNSLGNGLAYEDFSFPIFLLEDENETKVIKQETFDYIGSSRMVYDMEKGKFPVQLENVDSFVELGQVALRTSLELWMHTDPVSQKNESVRNQVEDLLATLEKSGAGVPAVILRRPNQSQPLPPSSLQRFLRARNISGVVLADHSGAFHNKYYQSIYDTAENINVSYPEWLSPEEDLNFVTDTAKALADVATVLGRALYELAGGTNFSDTVQADPQTVTRLLYGFLIKANNSWFQSILRQDLRSYLGDGPLQHYIAVSSPTNTTYVVQYALANLTGTVVNLTREQCQDPSKVPSENKDLYEYSWVQGPLHSNETDRLPRCVRSTARLARALSPAFELSQWSSTEYSTWTESRWKDIRARIFLIASKELELITLTVGFGILIFSLIVTYCINAKADVLFIAPREPGAVSY

Target ORF information:

RefSeq Version	NM_001290186.2
Organism	Homo sapiens(human)
Definition	Homo sapiens nicastrin (NCSTN), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001290186.2

ORF Insert Sequence:

ATGGCTACGG CAGGGGGTGG CTCTGGGGCT GACCCGGGAA GTCGGGGTCT CCTTCGCCTT 
CTGTCTTTCT GCGTCCTACT AGCAGGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGGAAACTTT TGACTACATT 
GGCAGCTCGA GGATGGTCTA CGATATGGAG AAGGGCAAGT TTCCCGTGCA GTTAGAGAAT 
GTTGACTCAT TTGTGGAGCT GGGACAGGTG GCCTTAAGAA CTTCATTAGA GCTTTGGATG 
CACACAGATC CTGTTTCTCA GAAAAATGAG TCTGTACGGA ACCAGGTGGA GGATCTCCTG 
GCCACATTGG AGAAGAGTGG TGCTGGTGTC CCTGCTGTCA TCCTCAGGAG GCCAAATCAG 
TCCCAGCCTC TCCCACCATC TTCCCTGCAG CGATTTCTTC GAGCTCGAAA CATCTCTGGC 
GTTGTTCTGG CTGACCACTC TGGTGCCTTC CATAACAAAT ATTACCAGAG TATTTACGAC 
ACTGCTGAGA ACATTAATGT GAGCTATCCC GAATGGCTGA GCCCTGAAGA GGACCTGAAC 
TTTGTAACAG ACACTGCCAA GGCCCTGGCA GATGTGGCCA CGGTGCTGGG ACGTGCTCTG 
TATGAGCTTG CAGGAGGAAC CAACTTCAGC GACACAGTTC AGGCTGATCC CCAAACGGTT 
ACCCGCCTGC TCTATGGGTT CCTGATTAAA GCCAACAACT CATGGTTCCA GTCTATCCTC 
AGGCAGGACC TAAGGTCCTA CTTGGGTGAC GGGCCTCTTC AACATTACAT CGCTGTCTCC 
AGCCCCACCA ACACCACTTA TGTTGTACAG TATGCCTTGG CAAATTTGAC TGGCACAGTG 
GTCAACCTCA CCCGAGAGCA GTGCCAGGAT CCAAGTAAAG TCCCAAGTGA AAACAAGGAT 
CTGTATGAGT ACTCATGGGT CCAGGGCCCT TTGCATTCTA ATGAGACGGA CCGACTCCCC 
CGGTGTGTGC GTTCTACTGC ACGATTAGCC AGGGCCTTGT CTCCTGCCTT TGAACTGAGT 
CAGTGGAGCT CTACTGAATA CTCTACATGG ACTGAGAGCC GCTGGAAAGA TATCCGTGCC 
CGGATATTTC TCATCGCCAG CAAAGAGCTT GAGTTGATCA CCCTGACAGT GGGCTTCGGC 
ATCCTCATCT TCTCCCTCAT CGTCACCTAC TGCATCAATG CCAAAGCTGA TGTCCTTTTC 
ATTGCTCCCC GGGAGCCAGG AGCTGTGTCA TACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NCSTN ( NM_001290186.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001277115.1 Homo sapiens nicastrin (NCSTN), transcript variant 3, mRNA.

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CloneID	OHu08810
Clone ID Related Accession (Same CDS sequence)	NM_001290186.2 , NM_001290186.1
Accession Version	NM_001290186.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1716bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	nicastrin isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF240468.1, AK299142.1, AL445230.11 and CN429672.1. Transcript Variant: This variant (3) lacks three alternate in-frame exons in the coding region compared to variant 1. The encoded isoform (3) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.11658.1, SRR1803613.125282.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTACGG CAGGGGGTGG CTCTGGGGCT GACCCGGGAA GTCGGGGTCT CCTTCGCCTT 
CTGTCTTTCT GCGTCCTACT AGCAGGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGGAAACTTT TGACTACATT 
GGCAGCTCGA GGATGGTCTA CGATATGGAG AAGGGCAAGT TTCCCGTGCA GTTAGAGAAT 
GTTGACTCAT TTGTGGAGCT GGGACAGGTG GCCTTAAGAA CTTCATTAGA GCTTTGGATG 
CACACAGATC CTGTTTCTCA GAAAAATGAG TCTGTACGGA ACCAGGTGGA GGATCTCCTG 
GCCACATTGG AGAAGAGTGG TGCTGGTGTC CCTGCTGTCA TCCTCAGGAG GCCAAATCAG 
TCCCAGCCTC TCCCACCATC TTCCCTGCAG CGATTTCTTC GAGCTCGAAA CATCTCTGGC 
GTTGTTCTGG CTGACCACTC TGGTGCCTTC CATAACAAAT ATTACCAGAG TATTTACGAC 
ACTGCTGAGA ACATTAATGT GAGCTATCCC GAATGGCTGA GCCCTGAAGA GGACCTGAAC 
TTTGTAACAG ACACTGCCAA GGCCCTGGCA GATGTGGCCA CGGTGCTGGG ACGTGCTCTG 
TATGAGCTTG CAGGAGGAAC CAACTTCAGC GACACAGTTC AGGCTGATCC CCAAACGGTT 
ACCCGCCTGC TCTATGGGTT CCTGATTAAA GCCAACAACT CATGGTTCCA GTCTATCCTC 
AGGCAGGACC TAAGGTCCTA CTTGGGTGAC GGGCCTCTTC AACATTACAT CGCTGTCTCC 
AGCCCCACCA ACACCACTTA TGTTGTACAG TATGCCTTGG CAAATTTGAC TGGCACAGTG 
GTCAACCTCA CCCGAGAGCA GTGCCAGGAT CCAAGTAAAG TCCCAAGTGA AAACAAGGAT 
CTGTATGAGT ACTCATGGGT CCAGGGCCCT TTGCATTCTA ATGAGACGGA CCGACTCCCC 
CGGTGTGTGC GTTCTACTGC ACGATTAGCC AGGGCCTTGT CTCCTGCCTT TGAACTGAGT 
CAGTGGAGCT CTACTGAATA CTCTACATGG ACTGAGAGCC GCTGGAAAGA TATCCGTGCC 
CGGATATTTC TCATCGCCAG CAAAGAGCTT GAGTTGATCA CCCTGACAGT GGGCTTCGGC 
ATCCTCATCT TCTCCCTCAT CGTCACCTAC TGCATCAATG CCAAAGCTGA TGTCCTTTTC 
ATTGCTCCCC GGGAGCCAGG AGCTGTGTCA TACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001277115.1
CDS	125..1840
Translation	MATAGGGSGADPGSRGLLRLLSFCVLLAGLCRGNSVERKIYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSPSVQCPNDGFGVYSNSYGPEFAHCREIQWNSLGNGLAYEDFSFPIFLLEDENETKVIKQETFDYIGSSRMVYDMEKGKFPVQLENVDSFVELGQVALRTSLELWMHTDPVSQKNESVRNQVEDLLATLEKSGAGVPAVILRRPNQSQPLPPSSLQRFLRARNISGVVLADHSGAFHNKYYQSIYDTAENINVSYPEWLSPEEDLNFVTDTAKALADVATVLGRALYELAGGTNFSDTVQADPQTVTRLLYGFLIKANNSWFQSILRQDLRSYLGDGPLQHYIAVSSPTNTTYVVQYALANLTGTVVNLTREQCQDPSKVPSENKDLYEYSWVQGPLHSNETDRLPRCVRSTARLARALSPAFELSQWSSTEYSTWTESRWKDIRARIFLIASKELELITLTVGFGILIFSLIVTYCINAKADVLFIAPREPGAVSY

Target ORF information:

RefSeq Version	NM_001290186.1
Organism	Homo sapiens(human)
Definition	Homo sapiens nicastrin (NCSTN), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001290186.1

ORF Insert Sequence:

ATGGCTACGG CAGGGGGTGG CTCTGGGGCT GACCCGGGAA GTCGGGGTCT CCTTCGCCTT 
CTGTCTTTCT GCGTCCTACT AGCAGGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGGAAACTTT TGACTACATT 
GGCAGCTCGA GGATGGTCTA CGATATGGAG AAGGGCAAGT TTCCCGTGCA GTTAGAGAAT 
GTTGACTCAT TTGTGGAGCT GGGACAGGTG GCCTTAAGAA CTTCATTAGA GCTTTGGATG 
CACACAGATC CTGTTTCTCA GAAAAATGAG TCTGTACGGA ACCAGGTGGA GGATCTCCTG 
GCCACATTGG AGAAGAGTGG TGCTGGTGTC CCTGCTGTCA TCCTCAGGAG GCCAAATCAG 
TCCCAGCCTC TCCCACCATC TTCCCTGCAG CGATTTCTTC GAGCTCGAAA CATCTCTGGC 
GTTGTTCTGG CTGACCACTC TGGTGCCTTC CATAACAAAT ATTACCAGAG TATTTACGAC 
ACTGCTGAGA ACATTAATGT GAGCTATCCC GAATGGCTGA GCCCTGAAGA GGACCTGAAC 
TTTGTAACAG ACACTGCCAA GGCCCTGGCA GATGTGGCCA CGGTGCTGGG ACGTGCTCTG 
TATGAGCTTG CAGGAGGAAC CAACTTCAGC GACACAGTTC AGGCTGATCC CCAAACGGTT 
ACCCGCCTGC TCTATGGGTT CCTGATTAAA GCCAACAACT CATGGTTCCA GTCTATCCTC 
AGGCAGGACC TAAGGTCCTA CTTGGGTGAC GGGCCTCTTC AACATTACAT CGCTGTCTCC 
AGCCCCACCA ACACCACTTA TGTTGTACAG TATGCCTTGG CAAATTTGAC TGGCACAGTG 
GTCAACCTCA CCCGAGAGCA GTGCCAGGAT CCAAGTAAAG TCCCAAGTGA AAACAAGGAT 
CTGTATGAGT ACTCATGGGT CCAGGGCCCT TTGCATTCTA ATGAGACGGA CCGACTCCCC 
CGGTGTGTGC GTTCTACTGC ACGATTAGCC AGGGCCTTGT CTCCTGCCTT TGAACTGAGT 
CAGTGGAGCT CTACTGAATA CTCTACATGG ACTGAGAGCC GCTGGAAAGA TATCCGTGCC 
CGGATATTTC TCATCGCCAG CAAAGAGCTT GAGTTGATCA CCCTGACAGT GGGCTTCGGC 
ATCCTCATCT TCTCCCTCAT CGTCACCTAC TGCATCAATG CCAAAGCTGA TGTCCTTTTC 
ATTGCTCCCC GGGAGCCAGG AGCTGTGTCA TACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NCSTN ( NM_001349729.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001336658.1 Homo sapiens nicastrin (NCSTN), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu66123
Clone ID Related Accession (Same CDS sequence)	NM_001349729.1 , NM_001349729.2
Accession Version	NM_001349729.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	nicastrin isoform 4 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF240468.1, AL445230.11 and H15133.1. On Apr 7, 2017 this sequence version replaced XM_011509363.2. Transcript Variant: This variant (5) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. It encodes isoform 5, which is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.154849.1, SRR1660807.263787.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END##

ATGGCTACGG CAGGGGGTGG CTCTGGGGCT GACCCGGGAA GTCGGGGTCT CCTTCGCCTT 
CTGTCTTTCT GCGTCCTACT AGCAGGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGTGCTATCA AGATCACAAC 
CTGAGTCAGA ATGGCTCAGC ACCAACCTTC CCACTATGTG CCATGCAGCT CTTTTCACAC 
ATGCATGCTG TCATCAGCAC TGCCACCTGC ATGCGGCGCA GCTCCATCCA AAGCACCTTC 
AGCATCAACC CAGAAATCGT CTGTGACCCC CTGTCTGATT ACAATGTGTG GAGCATGCTA 
AAGCCTATAA ATACAACTGG GACATTAAAG CCTGACGACA GGGTTGTGGT TGCTGCCACC 
CGGCTGGATA GTCGTTCCTT TTTCTGGAAT GTGGCCCCAG GGGCTGAAAG CGCAGTGGCT 
TCCTTTGTCA CCCAGCTGGC TGCTGCTGAA GCTTTGCAAA AGGCACCTGA TGTGACCACC 
CTGCCCCGCA ATGTCATGTT TGTCTTCTTT CAAGGGGAAA CTTTTGACTA CATTGGCAGC 
TCGAGGATGG TCTACGATAT GGAGAAGGGC AAGTTTCCCG TGCAGTTAGA GAATGTTGAC 
TCATTTGTGG AGCTGGGACA GGTGGCCTTA AGAACTTCAT TAGAGCTTTG GATGCACACA 
GATCCTGTTT CTCAGAAAAA TGAGTCTGTA CGGAACCAGG TGGAGGATCT CCTGGCCACA 
TTGGAGAAGA GTGGTGCTGG TGTCCCTGCT GTCATCCTCA GGAGGCCAAA TCAGTCCCAG 
CCTCTCCCAC CATCTTCCCT GCAGCGATTT CTTCGAGCTC GAAACATCTC TGGCGTTGTT 
CTGGCTGACC ACTCTGGTGC CTTCCATAAC AAATATTACC AGAGTATTTA CGACACTGCT 
GAGAACATTA ATGTGAGCTA TCCCGAATGG CTGAGCCCTG AAGAGGACCT GAACTTTGTA 
ACAGACACTG CCAAGGCCCT GGCAGATGTG GCCACGGTGC TGGGACGTGC TCTGTATGAG 
CTTGCAGGAG GAACCAACTT CAGCGACACA GTTCAGGCTG ATCCCCAAAC GGTTACCCGC 
CTGCTCTATG GGTTCCTGAT TAAAGCCAAC AACTCATGGT TCCAGTCTAT CCTCAGGCAG 
GACCTAAGGT CCTACTTGGG TGACGGGCCT CTTCAACATT ACATCGCTGT CTCCAGCCCC 
ACCAACACCA CTTATGTTGT ACAGTATGCC TTGGCAAATT TGACTGGCAC AGTGGTCAAC 
CTCACCCGAG AGCAGTGCCA GGATCCAAGT AAAGTCCCAA GTGAAAACAA GGATTTGATC 
ACCCTGACAG TGGGCTTCGG CATCCTCATC TTCTCCCTCA TCGTCACCTA CTGCATCAAT 
GCCAAAGCTG ATGTCCTTTT CATTGCTCCC CGGGAGCCAG GAGCTGTGTC ATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001336658.1
CDS	125..2041
Translation	MATAGGGSGADPGSRGLLRLLSFCVLLAGLCRGNSVERKIYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSPSVQCPNDGFGVYSNSYGPEFAHCREIQWNSLGNGLAYEDFSFPIFLLEDENETKVIKQCYQDHNLSQNGSAPTFPLCAMQLFSHMHAVISTATCMRRSSIQSTFSINPEIVCDPLSDYNVWSMLKPINTTGTLKPDDRVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEALQKAPDVTTLPRNVMFVFFQGETFDYIGSSRMVYDMEKGKFPVQLENVDSFVELGQVALRTSLELWMHTDPVSQKNESVRNQVEDLLATLEKSGAGVPAVILRRPNQSQPLPPSSLQRFLRARNISGVVLADHSGAFHNKYYQSIYDTAENINVSYPEWLSPEEDLNFVTDTAKALADVATVLGRALYELAGGTNFSDTVQADPQTVTRLLYGFLIKANNSWFQSILRQDLRSYLGDGPLQHYIAVSSPTNTTYVVQYALANLTGTVVNLTREQCQDPSKVPSENKDLITLTVGFGILIFSLIVTYCINAKADVLFIAPREPGAVSY

Target ORF information:

RefSeq Version	NM_001349729.1
Organism	Homo sapiens(human)
Definition	Homo sapiens nicastrin (NCSTN), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001349729.1

ORF Insert Sequence:

ATGGCTACGG CAGGGGGTGG CTCTGGGGCT GACCCGGGAA GTCGGGGTCT CCTTCGCCTT 
CTGTCTTTCT GCGTCCTACT AGCAGGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGTGCTATCA AGATCACAAC 
CTGAGTCAGA ATGGCTCAGC ACCAACCTTC CCACTATGTG CCATGCAGCT CTTTTCACAC 
ATGCATGCTG TCATCAGCAC TGCCACCTGC ATGCGGCGCA GCTCCATCCA AAGCACCTTC 
AGCATCAACC CAGAAATCGT CTGTGACCCC CTGTCTGATT ACAATGTGTG GAGCATGCTA 
AAGCCTATAA ATACAACTGG GACATTAAAG CCTGACGACA GGGTTGTGGT TGCTGCCACC 
CGGCTGGATA GTCGTTCCTT TTTCTGGAAT GTGGCCCCAG GGGCTGAAAG CGCAGTGGCT 
TCCTTTGTCA CCCAGCTGGC TGCTGCTGAA GCTTTGCAAA AGGCACCTGA TGTGACCACC 
CTGCCCCGCA ATGTCATGTT TGTCTTCTTT CAAGGGGAAA CTTTTGACTA CATTGGCAGC 
TCGAGGATGG TCTACGATAT GGAGAAGGGC AAGTTTCCCG TGCAGTTAGA GAATGTTGAC 
TCATTTGTGG AGCTGGGACA GGTGGCCTTA AGAACTTCAT TAGAGCTTTG GATGCACACA 
GATCCTGTTT CTCAGAAAAA TGAGTCTGTA CGGAACCAGG TGGAGGATCT CCTGGCCACA 
TTGGAGAAGA GTGGTGCTGG TGTCCCTGCT GTCATCCTCA GGAGGCCAAA TCAGTCCCAG 
CCTCTCCCAC CATCTTCCCT GCAGCGATTT CTTCGAGCTC GAAACATCTC TGGCGTTGTT 
CTGGCTGACC ACTCTGGTGC CTTCCATAAC AAATATTACC AGAGTATTTA CGACACTGCT 
GAGAACATTA ATGTGAGCTA TCCCGAATGG CTGAGCCCTG AAGAGGACCT GAACTTTGTA 
ACAGACACTG CCAAGGCCCT GGCAGATGTG GCCACGGTGC TGGGACGTGC TCTGTATGAG 
CTTGCAGGAG GAACCAACTT CAGCGACACA GTTCAGGCTG ATCCCCAAAC GGTTACCCGC 
CTGCTCTATG GGTTCCTGAT TAAAGCCAAC AACTCATGGT TCCAGTCTAT CCTCAGGCAG 
GACCTAAGGT CCTACTTGGG TGACGGGCCT CTTCAACATT ACATCGCTGT CTCCAGCCCC 
ACCAACACCA CTTATGTTGT ACAGTATGCC TTGGCAAATT TGACTGGCAC AGTGGTCAAC 
CTCACCCGAG AGCAGTGCCA GGATCCAAGT AAAGTCCCAA GTGAAAACAA GGATTTGATC 
ACCCTGACAG TGGGCTTCGG CATCCTCATC TTCTCCCTCA TCGTCACCTA CTGCATCAAT 
GCCAAAGCTG ATGTCCTTTT CATTGCTCCC CGGGAGCCAG GAGCTGTGTC ATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NCSTN ( NM_001349729.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001336658.1 Homo sapiens nicastrin (NCSTN), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu66123
Clone ID Related Accession (Same CDS sequence)	NM_001349729.1 , NM_001349729.2
Accession Version	NM_001349729.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1917bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	nicastrin isoform 4 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL445230.11 and H15133.1. On May 31, 2019 this sequence version replaced NM_001349729.1. Transcript Variant: This variant (5) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. It encodes isoform 5, which is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.179413.1, SRR1660807.263787.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END##

ATGGCTACGG CAGGGGGTGG CTCTGGGGCT GACCCGGGAA GTCGGGGTCT CCTTCGCCTT 
CTGTCTTTCT GCGTCCTACT AGCAGGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGTGCTATCA AGATCACAAC 
CTGAGTCAGA ATGGCTCAGC ACCAACCTTC CCACTATGTG CCATGCAGCT CTTTTCACAC 
ATGCATGCTG TCATCAGCAC TGCCACCTGC ATGCGGCGCA GCTCCATCCA AAGCACCTTC 
AGCATCAACC CAGAAATCGT CTGTGACCCC CTGTCTGATT ACAATGTGTG GAGCATGCTA 
AAGCCTATAA ATACAACTGG GACATTAAAG CCTGACGACA GGGTTGTGGT TGCTGCCACC 
CGGCTGGATA GTCGTTCCTT TTTCTGGAAT GTGGCCCCAG GGGCTGAAAG CGCAGTGGCT 
TCCTTTGTCA CCCAGCTGGC TGCTGCTGAA GCTTTGCAAA AGGCACCTGA TGTGACCACC 
CTGCCCCGCA ATGTCATGTT TGTCTTCTTT CAAGGGGAAA CTTTTGACTA CATTGGCAGC 
TCGAGGATGG TCTACGATAT GGAGAAGGGC AAGTTTCCCG TGCAGTTAGA GAATGTTGAC 
TCATTTGTGG AGCTGGGACA GGTGGCCTTA AGAACTTCAT TAGAGCTTTG GATGCACACA 
GATCCTGTTT CTCAGAAAAA TGAGTCTGTA CGGAACCAGG TGGAGGATCT CCTGGCCACA 
TTGGAGAAGA GTGGTGCTGG TGTCCCTGCT GTCATCCTCA GGAGGCCAAA TCAGTCCCAG 
CCTCTCCCAC CATCTTCCCT GCAGCGATTT CTTCGAGCTC GAAACATCTC TGGCGTTGTT 
CTGGCTGACC ACTCTGGTGC CTTCCATAAC AAATATTACC AGAGTATTTA CGACACTGCT 
GAGAACATTA ATGTGAGCTA TCCCGAATGG CTGAGCCCTG AAGAGGACCT GAACTTTGTA 
ACAGACACTG CCAAGGCCCT GGCAGATGTG GCCACGGTGC TGGGACGTGC TCTGTATGAG 
CTTGCAGGAG GAACCAACTT CAGCGACACA GTTCAGGCTG ATCCCCAAAC GGTTACCCGC 
CTGCTCTATG GGTTCCTGAT TAAAGCCAAC AACTCATGGT TCCAGTCTAT CCTCAGGCAG 
GACCTAAGGT CCTACTTGGG TGACGGGCCT CTTCAACATT ACATCGCTGT CTCCAGCCCC 
ACCAACACCA CTTATGTTGT ACAGTATGCC TTGGCAAATT TGACTGGCAC AGTGGTCAAC 
CTCACCCGAG AGCAGTGCCA GGATCCAAGT AAAGTCCCAA GTGAAAACAA GGATTTGATC 
ACCCTGACAG TGGGCTTCGG CATCCTCATC TTCTCCCTCA TCGTCACCTA CTGCATCAAT 
GCCAAAGCTG ATGTCCTTTT CATTGCTCCC CGGGAGCCAG GAGCTGTGTC ATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001336658.1
CDS	15..1931
Translation	MATAGGGSGADPGSRGLLRLLSFCVLLAGLCRGNSVERKIYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSPSVQCPNDGFGVYSNSYGPEFAHCREIQWNSLGNGLAYEDFSFPIFLLEDENETKVIKQCYQDHNLSQNGSAPTFPLCAMQLFSHMHAVISTATCMRRSSIQSTFSINPEIVCDPLSDYNVWSMLKPINTTGTLKPDDRVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEALQKAPDVTTLPRNVMFVFFQGETFDYIGSSRMVYDMEKGKFPVQLENVDSFVELGQVALRTSLELWMHTDPVSQKNESVRNQVEDLLATLEKSGAGVPAVILRRPNQSQPLPPSSLQRFLRARNISGVVLADHSGAFHNKYYQSIYDTAENINVSYPEWLSPEEDLNFVTDTAKALADVATVLGRALYELAGGTNFSDTVQADPQTVTRLLYGFLIKANNSWFQSILRQDLRSYLGDGPLQHYIAVSSPTNTTYVVQYALANLTGTVVNLTREQCQDPSKVPSENKDLITLTVGFGILIFSLIVTYCINAKADVLFIAPREPGAVSY

Target ORF information:

RefSeq Version	NM_001349729.2
Organism	Homo sapiens(human)
Definition	Homo sapiens nicastrin (NCSTN), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001349729.2

ORF Insert Sequence:

ATGGCTACGG CAGGGGGTGG CTCTGGGGCT GACCCGGGAA GTCGGGGTCT CCTTCGCCTT 
CTGTCTTTCT GCGTCCTACT AGCAGGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGTGCTATCA AGATCACAAC 
CTGAGTCAGA ATGGCTCAGC ACCAACCTTC CCACTATGTG CCATGCAGCT CTTTTCACAC 
ATGCATGCTG TCATCAGCAC TGCCACCTGC ATGCGGCGCA GCTCCATCCA AAGCACCTTC 
AGCATCAACC CAGAAATCGT CTGTGACCCC CTGTCTGATT ACAATGTGTG GAGCATGCTA 
AAGCCTATAA ATACAACTGG GACATTAAAG CCTGACGACA GGGTTGTGGT TGCTGCCACC 
CGGCTGGATA GTCGTTCCTT TTTCTGGAAT GTGGCCCCAG GGGCTGAAAG CGCAGTGGCT 
TCCTTTGTCA CCCAGCTGGC TGCTGCTGAA GCTTTGCAAA AGGCACCTGA TGTGACCACC 
CTGCCCCGCA ATGTCATGTT TGTCTTCTTT CAAGGGGAAA CTTTTGACTA CATTGGCAGC 
TCGAGGATGG TCTACGATAT GGAGAAGGGC AAGTTTCCCG TGCAGTTAGA GAATGTTGAC 
TCATTTGTGG AGCTGGGACA GGTGGCCTTA AGAACTTCAT TAGAGCTTTG GATGCACACA 
GATCCTGTTT CTCAGAAAAA TGAGTCTGTA CGGAACCAGG TGGAGGATCT CCTGGCCACA 
TTGGAGAAGA GTGGTGCTGG TGTCCCTGCT GTCATCCTCA GGAGGCCAAA TCAGTCCCAG 
CCTCTCCCAC CATCTTCCCT GCAGCGATTT CTTCGAGCTC GAAACATCTC TGGCGTTGTT 
CTGGCTGACC ACTCTGGTGC CTTCCATAAC AAATATTACC AGAGTATTTA CGACACTGCT 
GAGAACATTA ATGTGAGCTA TCCCGAATGG CTGAGCCCTG AAGAGGACCT GAACTTTGTA 
ACAGACACTG CCAAGGCCCT GGCAGATGTG GCCACGGTGC TGGGACGTGC TCTGTATGAG 
CTTGCAGGAG GAACCAACTT CAGCGACACA GTTCAGGCTG ATCCCCAAAC GGTTACCCGC 
CTGCTCTATG GGTTCCTGAT TAAAGCCAAC AACTCATGGT TCCAGTCTAT CCTCAGGCAG 
GACCTAAGGT CCTACTTGGG TGACGGGCCT CTTCAACATT ACATCGCTGT CTCCAGCCCC 
ACCAACACCA CTTATGTTGT ACAGTATGCC TTGGCAAATT TGACTGGCAC AGTGGTCAAC 
CTCACCCGAG AGCAGTGCCA GGATCCAAGT AAAGTCCCAA GTGAAAACAA GGATTTGATC 
ACCCTGACAG TGGGCTTCGG CATCCTCATC TTCTCCCTCA TCGTCACCTA CTGCATCAAT 
GCCAAAGCTG ATGTCCTTTT CATTGCTCCC CGGGAGCCAG GAGCTGTGTC ATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NCSTN ( XM_005245053.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005245110.1 Homo sapiens nicastrin (NCSTN), transcript variant X2, mRNA.

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CloneID	OHu34278
Clone ID Related Accession (Same CDS sequence)	XM_005245053.4 , XM_005245053.5
Accession Version	XM_005245053.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1188bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	nicastrin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005245053.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTACGG CAGGGGGTGG CTCTGGGGCT GACCCGGGAA GTCGGGGTCT CCTTCGCCTT 
CTGTCTTTCT GCGTCCTACT AGCAGGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGTGCTATCA AGATCACAAC 
CTGAGTCAGA ATGGCTCAGC ACCAACCTTC CCACTATGTG CCATGCAGCT CTTTTCACAC 
ATGCATGCTG TCATCAGCAC TGCCACCTGC ATGCGGCGCA GCTCCATCCA AAGCACCTTC 
AGCATCAACC CAGAAATCGT CTGTGACCCC CTGTCTGATT ACAATGTGTG GAGCATGCTA 
AAGCCTATAA ATACAACTGG GACATTAAAG CCTGACGACA GGGTTGTGGT TGCTGCCACC 
CGGCTGGATA GTCGTTCCTT TTTCTGGAAT GTGGCCCCAG GGGCTGAAAG CGCAGTGGCT 
TCCTTTGTCA CCCAGCTGGC TGCTGCTGAA GCTTTGCAAA AGGCACCTGA TGTGACCACC 
CTGCCCCGCA ATGTCATGTT TGTCTTCTTT CAAGGGGAAA CTTTTGACTA CATTGGCAGC 
TCGAGGATGG TCTACGATAT GGAGAAGGGC AAGTTTCCCG TGCAGTTAGA GAATGTTGAC 
TCATTTGTGG AGCTGGGACA GGTGGCCTTA AGAACTTCAT TAGAGCTTTG GATGCACACA 
GATCCTGTTT CTCAGAAAAA TGAGTCTGTA CGGAACCAGG GCCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005245110.1
CDS	342..1529
Translation	MATAGGGSGADPGSRGLLRLLSFCVLLAGLCRGNSVERKIYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSPSVQCPNDGFGVYSNSYGPEFAHCREIQWNSLGNGLAYEDFSFPIFLLEDENETKVIKQCYQDHNLSQNGSAPTFPLCAMQLFSHMHAVISTATCMRRSSIQSTFSINPEIVCDPLSDYNVWSMLKPINTTGTLKPDDRVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEALQKAPDVTTLPRNVMFVFFQGETFDYIGSSRMVYDMEKGKFPVQLENVDSFVELGQVALRTSLELWMHTDPVSQKNESVRNQGL

Target ORF information:

RefSeq Version	XM_005245053.4
Organism	Homo sapiens(human)
Definition	Homo sapiens nicastrin (NCSTN), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005245053.4

ORF Insert Sequence:

ATGGCTACGG CAGGGGGTGG CTCTGGGGCT GACCCGGGAA GTCGGGGTCT CCTTCGCCTT 
CTGTCTTTCT GCGTCCTACT AGCAGGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGTGCTATCA AGATCACAAC 
CTGAGTCAGA ATGGCTCAGC ACCAACCTTC CCACTATGTG CCATGCAGCT CTTTTCACAC 
ATGCATGCTG TCATCAGCAC TGCCACCTGC ATGCGGCGCA GCTCCATCCA AAGCACCTTC 
AGCATCAACC CAGAAATCGT CTGTGACCCC CTGTCTGATT ACAATGTGTG GAGCATGCTA 
AAGCCTATAA ATACAACTGG GACATTAAAG CCTGACGACA GGGTTGTGGT TGCTGCCACC 
CGGCTGGATA GTCGTTCCTT TTTCTGGAAT GTGGCCCCAG GGGCTGAAAG CGCAGTGGCT 
TCCTTTGTCA CCCAGCTGGC TGCTGCTGAA GCTTTGCAAA AGGCACCTGA TGTGACCACC 
CTGCCCCGCA ATGTCATGTT TGTCTTCTTT CAAGGGGAAA CTTTTGACTA CATTGGCAGC 
TCGAGGATGG TCTACGATAT GGAGAAGGGC AAGTTTCCCG TGCAGTTAGA GAATGTTGAC 
TCATTTGTGG AGCTGGGACA GGTGGCCTTA AGAACTTCAT TAGAGCTTTG GATGCACACA 
GATCCTGTTT CTCAGAAAAA TGAGTCTGTA CGGAACCAGG GCCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NCSTN ( XM_005245053.5 ) cDNA ORF clone, Homo sapiens(human) -> XP_005245110.1 Homo sapiens nicastrin (NCSTN), transcript variant X1, mRNA.

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CloneID	OHu34278
Clone ID Related Accession (Same CDS sequence)	XM_005245053.4 , XM_005245053.5
Accession Version	XM_005245053.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1188bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	nicastrin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005245053.4. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTACGG CAGGGGGTGG CTCTGGGGCT GACCCGGGAA GTCGGGGTCT CCTTCGCCTT 
CTGTCTTTCT GCGTCCTACT AGCAGGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGTGCTATCA AGATCACAAC 
CTGAGTCAGA ATGGCTCAGC ACCAACCTTC CCACTATGTG CCATGCAGCT CTTTTCACAC 
ATGCATGCTG TCATCAGCAC TGCCACCTGC ATGCGGCGCA GCTCCATCCA AAGCACCTTC 
AGCATCAACC CAGAAATCGT CTGTGACCCC CTGTCTGATT ACAATGTGTG GAGCATGCTA 
AAGCCTATAA ATACAACTGG GACATTAAAG CCTGACGACA GGGTTGTGGT TGCTGCCACC 
CGGCTGGATA GTCGTTCCTT TTTCTGGAAT GTGGCCCCAG GGGCTGAAAG CGCAGTGGCT 
TCCTTTGTCA CCCAGCTGGC TGCTGCTGAA GCTTTGCAAA AGGCACCTGA TGTGACCACC 
CTGCCCCGCA ATGTCATGTT TGTCTTCTTT CAAGGGGAAA CTTTTGACTA CATTGGCAGC 
TCGAGGATGG TCTACGATAT GGAGAAGGGC AAGTTTCCCG TGCAGTTAGA GAATGTTGAC 
TCATTTGTGG AGCTGGGACA GGTGGCCTTA AGAACTTCAT TAGAGCTTTG GATGCACACA 
GATCCTGTTT CTCAGAAAAA TGAGTCTGTA CGGAACCAGG GCCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005245110.1
CDS	70..1257
Translation	MATAGGGSGADPGSRGLLRLLSFCVLLAGLCRGNSVERKIYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSPSVQCPNDGFGVYSNSYGPEFAHCREIQWNSLGNGLAYEDFSFPIFLLEDENETKVIKQCYQDHNLSQNGSAPTFPLCAMQLFSHMHAVISTATCMRRSSIQSTFSINPEIVCDPLSDYNVWSMLKPINTTGTLKPDDRVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEALQKAPDVTTLPRNVMFVFFQGETFDYIGSSRMVYDMEKGKFPVQLENVDSFVELGQVALRTSLELWMHTDPVSQKNESVRNQGL

Target ORF information:

RefSeq Version	XM_005245053.5
Organism	Homo sapiens(human)
Definition	Homo sapiens nicastrin (NCSTN), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005245053.5

ORF Insert Sequence:

ATGGCTACGG CAGGGGGTGG CTCTGGGGCT GACCCGGGAA GTCGGGGTCT CCTTCGCCTT 
CTGTCTTTCT GCGTCCTACT AGCAGGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGTGCTATCA AGATCACAAC 
CTGAGTCAGA ATGGCTCAGC ACCAACCTTC CCACTATGTG CCATGCAGCT CTTTTCACAC 
ATGCATGCTG TCATCAGCAC TGCCACCTGC ATGCGGCGCA GCTCCATCCA AAGCACCTTC 
AGCATCAACC CAGAAATCGT CTGTGACCCC CTGTCTGATT ACAATGTGTG GAGCATGCTA 
AAGCCTATAA ATACAACTGG GACATTAAAG CCTGACGACA GGGTTGTGGT TGCTGCCACC 
CGGCTGGATA GTCGTTCCTT TTTCTGGAAT GTGGCCCCAG GGGCTGAAAG CGCAGTGGCT 
TCCTTTGTCA CCCAGCTGGC TGCTGCTGAA GCTTTGCAAA AGGCACCTGA TGTGACCACC 
CTGCCCCGCA ATGTCATGTT TGTCTTCTTT CAAGGGGAAA CTTTTGACTA CATTGGCAGC 
TCGAGGATGG TCTACGATAT GGAGAAGGGC AAGTTTCCCG TGCAGTTAGA GAATGTTGAC 
TCATTTGTGG AGCTGGGACA GGTGGCCTTA AGAACTTCAT TAGAGCTTTG GATGCACACA 
GATCCTGTTT CTCAGAAAAA TGAGTCTGTA CGGAACCAGG GCCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NCSTN ( NM_001290184.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001277113.1 Homo sapiens nicastrin (NCSTN), transcript variant 2, mRNA.

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CloneID	OHu08813
Clone ID Related Accession (Same CDS sequence)	NM_001290184.2 , NM_001290184.1
Accession Version	NM_001290184.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2070bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	nicastrin isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC047621.1, AL445230.11 and CN429672.1. This sequence is a reference standard in the RefSeqGene project. On May 31, 2019 this sequence version replaced NM_001290184.1. Transcript Variant: This variant (2) has a different 5' structure resulting in translation initiation at an alternate AUG compared to variant 1; the 5'-most AUG, as used in variant 1, is associated with a truncated ORF that would render the transcript a candidate for nonsense-mediated decay (NMD). Leaky scanning may allow translation initiation at the alternate AUG resulting in a shorter isoform (2) with a distinct N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC047621.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01820687 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACTTTA ATCTCATTTT AGAAAGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGTGCTATCA AGATCACAAC 
CTGAGTCAGA ATGGCTCAGC ACCAACCTTC CCACTATGTG CCATGCAGCT CTTTTCACAC 
ATGCATGCTG TCATCAGCAC TGCCACCTGC ATGCGGCGCA GCTCCATCCA AAGCACCTTC 
AGCATCAACC CAGAAATCGT CTGTGACCCC CTGTCTGATT ACAATGTGTG GAGCATGCTA 
AAGCCTATAA ATACAACTGG GACATTAAAG CCTGACGACA GGGTTGTGGT TGCTGCCACC 
CGGCTGGATA GTCGTTCCTT TTTCTGGAAT GTGGCCCCAG GGGCTGAAAG CGCAGTGGCT 
TCCTTTGTCA CCCAGCTGGC TGCTGCTGAA GCTTTGCAAA AGGCACCTGA TGTGACCACC 
CTGCCCCGCA ATGTCATGTT TGTCTTCTTT CAAGGGGAAA CTTTTGACTA CATTGGCAGC 
TCGAGGATGG TCTACGATAT GGAGAAGGGC AAGTTTCCCG TGCAGTTAGA GAATGTTGAC 
TCATTTGTGG AGCTGGGACA GGTGGCCTTA AGAACTTCAT TAGAGCTTTG GATGCACACA 
GATCCTGTTT CTCAGAAAAA TGAGTCTGTA CGGAACCAGG TGGAGGATCT CCTGGCCACA 
TTGGAGAAGA GTGGTGCTGG TGTCCCTGCT GTCATCCTCA GGAGGCCAAA TCAGTCCCAG 
CCTCTCCCAC CATCTTCCCT GCAGCGATTT CTTCGAGCTC GAAACATCTC TGGCGTTGTT 
CTGGCTGACC ACTCTGGTGC CTTCCATAAC AAATATTACC AGAGTATTTA CGACACTGCT 
GAGAACATTA ATGTGAGCTA TCCCGAATGG CTGAGCCCTG AAGAGGACCT GAACTTTGTA 
ACAGACACTG CCAAGGCCCT GGCAGATGTG GCCACGGTGC TGGGACGTGC TCTGTATGAG 
CTTGCAGGAG GAACCAACTT CAGCGACACA GTTCAGGCTG ATCCCCAAAC GGTTACCCGC 
CTGCTCTATG GGTTCCTGAT TAAAGCCAAC AACTCATGGT TCCAGTCTAT CCTCAGGCAG 
GACCTAAGGT CCTACTTGGG TGACGGGCCT CTTCAACATT ACATCGCTGT CTCCAGCCCC 
ACCAACACCA CTTATGTTGT ACAGTATGCC TTGGCAAATT TGACTGGCAC AGTGGTCAAC 
CTCACCCGAG AGCAGTGCCA GGATCCAAGT AAAGTCCCAA GTGAAAACAA GGATCTGTAT 
GAGTACTCAT GGGTCCAGGG CCCTTTGCAT TCTAATGAGA CGGACCGACT CCCCCGGTGT 
GTGCGTTCTA CTGCACGATT AGCCAGGGCC TTGTCTCCTG CCTTTGAACT GAGTCAGTGG 
AGCTCTACTG AATACTCTAC ATGGACTGAG AGCCGCTGGA AAGATATCCG TGCCCGGATA 
TTTCTCATCG CCAGCAAAGA GCTTGAGTTG ATCACCCTGA CAGTGGGCTT CGGCATCCTC 
ATCTTCTCCC TCATCGTCAC CTACTGCATC AATGCCAAAG CTGATGTCCT TTTCATTGCT 
CCCCGGGAGC CAGGAGCTGT GTCATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001277113.1
CDS	214..2283
Translation	MDFNLILESLCRGNSVERKIYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSPSVQCPNDGFGVYSNSYGPEFAHCREIQWNSLGNGLAYEDFSFPIFLLEDENETKVIKQCYQDHNLSQNGSAPTFPLCAMQLFSHMHAVISTATCMRRSSIQSTFSINPEIVCDPLSDYNVWSMLKPINTTGTLKPDDRVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEALQKAPDVTTLPRNVMFVFFQGETFDYIGSSRMVYDMEKGKFPVQLENVDSFVELGQVALRTSLELWMHTDPVSQKNESVRNQVEDLLATLEKSGAGVPAVILRRPNQSQPLPPSSLQRFLRARNISGVVLADHSGAFHNKYYQSIYDTAENINVSYPEWLSPEEDLNFVTDTAKALADVATVLGRALYELAGGTNFSDTVQADPQTVTRLLYGFLIKANNSWFQSILRQDLRSYLGDGPLQHYIAVSSPTNTTYVVQYALANLTGTVVNLTREQCQDPSKVPSENKDLYEYSWVQGPLHSNETDRLPRCVRSTARLARALSPAFELSQWSSTEYSTWTESRWKDIRARIFLIASKELELITLTVGFGILIFSLIVTYCINAKADVLFIAPREPGAVSY

Target ORF information:

RefSeq Version	NM_001290184.2
Organism	Homo sapiens(human)
Definition	Homo sapiens nicastrin (NCSTN), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001290184.2

ORF Insert Sequence:

ATGGACTTTA ATCTCATTTT AGAAAGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGTGCTATCA AGATCACAAC 
CTGAGTCAGA ATGGCTCAGC ACCAACCTTC CCACTATGTG CCATGCAGCT CTTTTCACAC 
ATGCATGCTG TCATCAGCAC TGCCACCTGC ATGCGGCGCA GCTCCATCCA AAGCACCTTC 
AGCATCAACC CAGAAATCGT CTGTGACCCC CTGTCTGATT ACAATGTGTG GAGCATGCTA 
AAGCCTATAA ATACAACTGG GACATTAAAG CCTGACGACA GGGTTGTGGT TGCTGCCACC 
CGGCTGGATA GTCGTTCCTT TTTCTGGAAT GTGGCCCCAG GGGCTGAAAG CGCAGTGGCT 
TCCTTTGTCA CCCAGCTGGC TGCTGCTGAA GCTTTGCAAA AGGCACCTGA TGTGACCACC 
CTGCCCCGCA ATGTCATGTT TGTCTTCTTT CAAGGGGAAA CTTTTGACTA CATTGGCAGC 
TCGAGGATGG TCTACGATAT GGAGAAGGGC AAGTTTCCCG TGCAGTTAGA GAATGTTGAC 
TCATTTGTGG AGCTGGGACA GGTGGCCTTA AGAACTTCAT TAGAGCTTTG GATGCACACA 
GATCCTGTTT CTCAGAAAAA TGAGTCTGTA CGGAACCAGG TGGAGGATCT CCTGGCCACA 
TTGGAGAAGA GTGGTGCTGG TGTCCCTGCT GTCATCCTCA GGAGGCCAAA TCAGTCCCAG 
CCTCTCCCAC CATCTTCCCT GCAGCGATTT CTTCGAGCTC GAAACATCTC TGGCGTTGTT 
CTGGCTGACC ACTCTGGTGC CTTCCATAAC AAATATTACC AGAGTATTTA CGACACTGCT 
GAGAACATTA ATGTGAGCTA TCCCGAATGG CTGAGCCCTG AAGAGGACCT GAACTTTGTA 
ACAGACACTG CCAAGGCCCT GGCAGATGTG GCCACGGTGC TGGGACGTGC TCTGTATGAG 
CTTGCAGGAG GAACCAACTT CAGCGACACA GTTCAGGCTG ATCCCCAAAC GGTTACCCGC 
CTGCTCTATG GGTTCCTGAT TAAAGCCAAC AACTCATGGT TCCAGTCTAT CCTCAGGCAG 
GACCTAAGGT CCTACTTGGG TGACGGGCCT CTTCAACATT ACATCGCTGT CTCCAGCCCC 
ACCAACACCA CTTATGTTGT ACAGTATGCC TTGGCAAATT TGACTGGCAC AGTGGTCAAC 
CTCACCCGAG AGCAGTGCCA GGATCCAAGT AAAGTCCCAA GTGAAAACAA GGATCTGTAT 
GAGTACTCAT GGGTCCAGGG CCCTTTGCAT TCTAATGAGA CGGACCGACT CCCCCGGTGT 
GTGCGTTCTA CTGCACGATT AGCCAGGGCC TTGTCTCCTG CCTTTGAACT GAGTCAGTGG 
AGCTCTACTG AATACTCTAC ATGGACTGAG AGCCGCTGGA AAGATATCCG TGCCCGGATA 
TTTCTCATCG CCAGCAAAGA GCTTGAGTTG ATCACCCTGA CAGTGGGCTT CGGCATCCTC 
ATCTTCTCCC TCATCGTCAC CTACTGCATC AATGCCAAAG CTGATGTCCT TTTCATTGCT 
CCCCGGGAGC CAGGAGCTGT GTCATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NCSTN ( NM_001290184.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001277113.1 Homo sapiens nicastrin (NCSTN), transcript variant 2, mRNA.

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CloneID	OHu08813
Clone ID Related Accession (Same CDS sequence)	NM_001290184.2 , NM_001290184.1
Accession Version	NM_001290184.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2070bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-22
Organism	Homo sapiens(human)
Product	nicastrin isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF240468.1, BC047621.1, AL445230.11 and CN429672.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (2) has a different 5' structure resulting in translation initiation at an alternate AUG compared to variant 1; the 5'-most AUG, as used in variant 1, is associated with a truncated ORF that would render the transcript a candidate for nonsense-mediated decay (NMD). Leaky scanning may allow translation initiation at the alternate AUG resulting in a shorter isoform (2) with a distinct N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC047621.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01820687 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACTTTA ATCTCATTTT AGAAAGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGTGCTATCA AGATCACAAC 
CTGAGTCAGA ATGGCTCAGC ACCAACCTTC CCACTATGTG CCATGCAGCT CTTTTCACAC 
ATGCATGCTG TCATCAGCAC TGCCACCTGC ATGCGGCGCA GCTCCATCCA AAGCACCTTC 
AGCATCAACC CAGAAATCGT CTGTGACCCC CTGTCTGATT ACAATGTGTG GAGCATGCTA 
AAGCCTATAA ATACAACTGG GACATTAAAG CCTGACGACA GGGTTGTGGT TGCTGCCACC 
CGGCTGGATA GTCGTTCCTT TTTCTGGAAT GTGGCCCCAG GGGCTGAAAG CGCAGTGGCT 
TCCTTTGTCA CCCAGCTGGC TGCTGCTGAA GCTTTGCAAA AGGCACCTGA TGTGACCACC 
CTGCCCCGCA ATGTCATGTT TGTCTTCTTT CAAGGGGAAA CTTTTGACTA CATTGGCAGC 
TCGAGGATGG TCTACGATAT GGAGAAGGGC AAGTTTCCCG TGCAGTTAGA GAATGTTGAC 
TCATTTGTGG AGCTGGGACA GGTGGCCTTA AGAACTTCAT TAGAGCTTTG GATGCACACA 
GATCCTGTTT CTCAGAAAAA TGAGTCTGTA CGGAACCAGG TGGAGGATCT CCTGGCCACA 
TTGGAGAAGA GTGGTGCTGG TGTCCCTGCT GTCATCCTCA GGAGGCCAAA TCAGTCCCAG 
CCTCTCCCAC CATCTTCCCT GCAGCGATTT CTTCGAGCTC GAAACATCTC TGGCGTTGTT 
CTGGCTGACC ACTCTGGTGC CTTCCATAAC AAATATTACC AGAGTATTTA CGACACTGCT 
GAGAACATTA ATGTGAGCTA TCCCGAATGG CTGAGCCCTG AAGAGGACCT GAACTTTGTA 
ACAGACACTG CCAAGGCCCT GGCAGATGTG GCCACGGTGC TGGGACGTGC TCTGTATGAG 
CTTGCAGGAG GAACCAACTT CAGCGACACA GTTCAGGCTG ATCCCCAAAC GGTTACCCGC 
CTGCTCTATG GGTTCCTGAT TAAAGCCAAC AACTCATGGT TCCAGTCTAT CCTCAGGCAG 
GACCTAAGGT CCTACTTGGG TGACGGGCCT CTTCAACATT ACATCGCTGT CTCCAGCCCC 
ACCAACACCA CTTATGTTGT ACAGTATGCC TTGGCAAATT TGACTGGCAC AGTGGTCAAC 
CTCACCCGAG AGCAGTGCCA GGATCCAAGT AAAGTCCCAA GTGAAAACAA GGATCTGTAT 
GAGTACTCAT GGGTCCAGGG CCCTTTGCAT TCTAATGAGA CGGACCGACT CCCCCGGTGT 
GTGCGTTCTA CTGCACGATT AGCCAGGGCC TTGTCTCCTG CCTTTGAACT GAGTCAGTGG 
AGCTCTACTG AATACTCTAC ATGGACTGAG AGCCGCTGGA AAGATATCCG TGCCCGGATA 
TTTCTCATCG CCAGCAAAGA GCTTGAGTTG ATCACCCTGA CAGTGGGCTT CGGCATCCTC 
ATCTTCTCCC TCATCGTCAC CTACTGCATC AATGCCAAAG CTGATGTCCT TTTCATTGCT 
CCCCGGGAGC CAGGAGCTGT GTCATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001277113.1
CDS	324..2393
Translation	MDFNLILESLCRGNSVERKIYIPLNKTAPCVRLLNATHQIGCQSSISGDTGVIHVVEKEEDLQWVLTDGPNPPYMVLLESKHFTRDLMEKLKGRTSRIAGLAVSLTKPSPASGFSPSVQCPNDGFGVYSNSYGPEFAHCREIQWNSLGNGLAYEDFSFPIFLLEDENETKVIKQCYQDHNLSQNGSAPTFPLCAMQLFSHMHAVISTATCMRRSSIQSTFSINPEIVCDPLSDYNVWSMLKPINTTGTLKPDDRVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEALQKAPDVTTLPRNVMFVFFQGETFDYIGSSRMVYDMEKGKFPVQLENVDSFVELGQVALRTSLELWMHTDPVSQKNESVRNQVEDLLATLEKSGAGVPAVILRRPNQSQPLPPSSLQRFLRARNISGVVLADHSGAFHNKYYQSIYDTAENINVSYPEWLSPEEDLNFVTDTAKALADVATVLGRALYELAGGTNFSDTVQADPQTVTRLLYGFLIKANNSWFQSILRQDLRSYLGDGPLQHYIAVSSPTNTTYVVQYALANLTGTVVNLTREQCQDPSKVPSENKDLYEYSWVQGPLHSNETDRLPRCVRSTARLARALSPAFELSQWSSTEYSTWTESRWKDIRARIFLIASKELELITLTVGFGILIFSLIVTYCINAKADVLFIAPREPGAVSY

Target ORF information:

RefSeq Version	NM_001290184.1
Organism	Homo sapiens(human)
Definition	Homo sapiens nicastrin (NCSTN), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001290184.1

ORF Insert Sequence:

ATGGACTTTA ATCTCATTTT AGAAAGTTTG TGCAGGGGAA ACTCAGTGGA GAGGAAGATA 
TATATCCCCT TAAATAAAAC AGCTCCCTGT GTTCGCCTGC TCAACGCCAC TCATCAGATT 
GGCTGCCAGT CTTCAATTAG TGGAGACACA GGGGTTATCC ACGTAGTAGA GAAAGAGGAG 
GACCTACAGT GGGTATTGAC TGATGGCCCC AACCCCCCTT ACATGGTTCT GCTGGAGAGC 
AAGCATTTTA CCAGGGATTT AATGGAGAAG CTGAAAGGGA GAACCAGCCG AATTGCTGGT 
CTTGCAGTGT CCTTGACCAA GCCCAGTCCT GCCTCAGGCT TCTCTCCTAG TGTACAGTGC 
CCAAATGATG GGTTTGGTGT TTACTCCAAT TCCTATGGGC CAGAGTTTGC TCACTGCAGA 
GAAATACAGT GGAATTCGCT GGGCAATGGT TTGGCTTATG AAGACTTTAG TTTCCCCATC 
TTTCTTCTTG AAGATGAAAA TGAAACCAAA GTCATCAAGC AGTGCTATCA AGATCACAAC 
CTGAGTCAGA ATGGCTCAGC ACCAACCTTC CCACTATGTG CCATGCAGCT CTTTTCACAC 
ATGCATGCTG TCATCAGCAC TGCCACCTGC ATGCGGCGCA GCTCCATCCA AAGCACCTTC 
AGCATCAACC CAGAAATCGT CTGTGACCCC CTGTCTGATT ACAATGTGTG GAGCATGCTA 
AAGCCTATAA ATACAACTGG GACATTAAAG CCTGACGACA GGGTTGTGGT TGCTGCCACC 
CGGCTGGATA GTCGTTCCTT TTTCTGGAAT GTGGCCCCAG GGGCTGAAAG CGCAGTGGCT 
TCCTTTGTCA CCCAGCTGGC TGCTGCTGAA GCTTTGCAAA AGGCACCTGA TGTGACCACC 
CTGCCCCGCA ATGTCATGTT TGTCTTCTTT CAAGGGGAAA CTTTTGACTA CATTGGCAGC 
TCGAGGATGG TCTACGATAT GGAGAAGGGC AAGTTTCCCG TGCAGTTAGA GAATGTTGAC 
TCATTTGTGG AGCTGGGACA GGTGGCCTTA AGAACTTCAT TAGAGCTTTG GATGCACACA 
GATCCTGTTT CTCAGAAAAA TGAGTCTGTA CGGAACCAGG TGGAGGATCT CCTGGCCACA 
TTGGAGAAGA GTGGTGCTGG TGTCCCTGCT GTCATCCTCA GGAGGCCAAA TCAGTCCCAG 
CCTCTCCCAC CATCTTCCCT GCAGCGATTT CTTCGAGCTC GAAACATCTC TGGCGTTGTT 
CTGGCTGACC ACTCTGGTGC CTTCCATAAC AAATATTACC AGAGTATTTA CGACACTGCT 
GAGAACATTA ATGTGAGCTA TCCCGAATGG CTGAGCCCTG AAGAGGACCT GAACTTTGTA 
ACAGACACTG CCAAGGCCCT GGCAGATGTG GCCACGGTGC TGGGACGTGC TCTGTATGAG 
CTTGCAGGAG GAACCAACTT CAGCGACACA GTTCAGGCTG ATCCCCAAAC GGTTACCCGC 
CTGCTCTATG GGTTCCTGAT TAAAGCCAAC AACTCATGGT TCCAGTCTAT CCTCAGGCAG 
GACCTAAGGT CCTACTTGGG TGACGGGCCT CTTCAACATT ACATCGCTGT CTCCAGCCCC 
ACCAACACCA CTTATGTTGT ACAGTATGCC TTGGCAAATT TGACTGGCAC AGTGGTCAAC 
CTCACCCGAG AGCAGTGCCA GGATCCAAGT AAAGTCCCAA GTGAAAACAA GGATCTGTAT 
GAGTACTCAT GGGTCCAGGG CCCTTTGCAT TCTAATGAGA CGGACCGACT CCCCCGGTGT 
GTGCGTTCTA CTGCACGATT AGCCAGGGCC TTGTCTCCTG CCTTTGAACT GAGTCAGTGG 
AGCTCTACTG AATACTCTAC ATGGACTGAG AGCCGCTGGA AAGATATCCG TGCCCGGATA 
TTTCTCATCG CCAGCAAAGA GCTTGAGTTG ATCACCCTGA CAGTGGGCTT CGGCATCCTC 
ATCTTCTCCC TCATCGTCAC CTACTGCATC AATGCCAAAG CTGATGTCCT TTTCATTGCT 
CCCCGGGAGC CAGGAGCTGT GTCATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	NCSTN
Entrez Gene ID	23385
Full Name	nicastrin
Synonyms	ATAG1874
General protein information	Preferred Names nicastrin Names nicastrin anterior pharynx-defective 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q23.2
Summary	This gene encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly. The cleavage of beta-amyloid precursor protein yields amyloid beta peptide, the main component of the neuritic plaque and the hallmark lesion in the brains of patients with Alzheimer's disease; however, the nature of the encoded protein's role in Alzheimer's disease is not known for certain. Mutations in this gene are associated with familial acne inversa. A pseudogene of this gene is present on chromosome 21. Alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Feb 2014].
Disorder MIM:	605254
Disorder Html:	Acne inversa, familial, 1, 142690 (3)

	NCSTN	XP_001117549.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001734	XP_321352.4
Caenorhabditis elegans (roundworm)	aph-2	NP_492712.2
Arabidopsis thaliana (thale cress)	AT3G52640	NP_974419.1
Homo sapiens (human)	NCSTN	NP_056146.1
Danio rerio (zebrafish)	ncstn	NP_001009556.1
Pan troglodytes (chimpanzee)	NCSTN	XP_003949661.1
Rattus norvegicus (Norway rat)	Ncstn	NP_777353.1
Drosophila melanogaster (fruit fly)	nct	NP_001262932.1
Bos taurus (cattle)	NCSTN	NP_001029647.1
Mus musculus (house mouse)	Ncstn	NP_067620.3
Canis lupus familiaris (dog)	NCSTN	XP_005640953.1
Gallus gallus (chicken)	NCSTN	NP_001004413.2
Oryza sativa (rice)	Os02g0736500	NP_001048054.1
Xenopus tropicalis (tropical clawed frog)	ncstn	NP_001123711.2

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

NCSTN cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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