Gene Symbol | SRGAP2 |
Entrez Gene ID | 23380 |
Full Name | SLIT-ROBO Rho GTPase activating protein 2 |
Synonyms | ARHGAP34,FNBP2,SRGAP2A,SRGAP3 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014]. |
Disorder MIM: |