UFL1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	UFL1
Entrez Gene ID	23376
Full Name	UFM1 specific ligase 1
Synonyms	KIAA0776,Maxer,NLBP,RCAD
General protein information	Preferred Names UFM1 specific ligase 1 Names E3 UFM1-protein ligase 1 LZAP-binding protein Regulator of CDK5RAP3 and DDRGK1 novel LZAP-binding protein regulator of C53/LZAP and DDRGK1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6q16.1
Disorder MIM:	613372

mRNA and Protein(s)

mRNA	Protein	Name
NM_015323.4	NP_056138.1	E3 UFM1-protein ligase 1
NM_015323.5	NP_056138.1	E3 UFM1-protein ligase 1

Pathways from BioSystems

Homologies

	UFL1	XP_001100312.1
Canis lupus familiaris (dog)	UFL1	XP_532236.4
Bos taurus (cattle)	UFL1	NP_001073745.1
Anopheles gambiae (African malaria mosquito)	UFL1_ANOGA	XP_317778.3
Arabidopsis thaliana (thale cress)	AT3G46220	NP_566883.4
Homo sapiens (human)	UFL1	NP_056138.1
Gallus gallus (chicken)	UFL1	NP_001096671.1
Mus musculus (house mouse)	Ufl1	NP_080470.2
Rattus norvegicus (Norway rat)	Ufl1	NP_001119751.1
Drosophila melanogaster (fruit fly)	CG1104	NP_001246957.1
Oryza sativa (rice)	Os05g0117600	NP_001174184.1
Xenopus tropicalis (tropical clawed frog)	ufl1	XP_002934919.2
Pan troglodytes (chimpanzee)	UFL1	XP_518643.2
Danio rerio (zebrafish)	ufl1	NP_956900.1

Gene Ontology
Bibliography

Related articles in PubMed

Modification of ASC1 by UFM1 is crucial for ER? transactivation and breast cancer development.
Yoo HM, Kang SH, Kim JY, Lee JE, Seong MW, Lee SW, Ka SH, Sou YS, Komatsu M, Tanaka K, Lee ST, Noh DY, Baek SH, Jeon YJ, Chung CH
Molecular cell56(2)261-74(2014 Oct)

Overexpression of a novel regulator of p120 catenin, NLBP, promotes lung adenocarcinoma proliferation.
Kim CH, Nam HS, Lee EH, Han SH, Cho HJ, Chung HJ, Lee NS, Choi SJ, Kim H, Ryu JS, Kwon J, Kim H
Cell cycle (Georgetown, Tex.)12(15)2443-53(2013 Aug)

Transcriptional regulation of the Ufm1 conjugation system in response to disturbance of the endoplasmic reticulum homeostasis and inhibition of vesicle trafficking.
Zhang Y, Zhang M, Wu J, Lei G, Li H
PloS one7(11)e48587(2012)

Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity.
Shiwaku H, Yoshimura N, Tamura T, Sone M, Ogishima S, Watase K, Tagawa K, Okazawa H
The EMBO journal29(14)2446-60(2010 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Overexpression of NLBP promotes the cell proliferation of lung adenocarcinoma through interacting with p120ctn.
Title: Overexpression of a novel regulator of p120 catenin, NLBP, promotes lung adenocarcinoma proliferation.

Results identify a novel molecule named multiple alpha-helix protein located at ER (Maxer) downregulated by mutant ataxin-1 (Atx1) in Bergmann glia.
Title: Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity.

The following UFL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the UFL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24870	NM_015323.5 Latest version!	Homo sapiens UFM1 specific ligase 1 (UFL1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu24870	NM_015323.4	Homo sapiens UFM1 specific ligase 1 (UFL1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

UFL1 ( NM_015323.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_056138.1 Homo sapiens UFM1 specific ligase 1 (UFL1), mRNA.

Price & Availability↑

CloneID	OHu24870
Clone ID Related Accession (Same CDS sequence)	NM_015323.4 , NM_015323.5
Accession Version	NM_015323.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2385bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	E3 UFM1-protein ligase 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP337693.1, AB018319.1 and BC028608.1. On Jul 31, 2008 this sequence version replaced NM_015323.3. ##Evidence-Data-START## Transcript exon combination :: BC036379.2, SRR1660805.196332.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGACG CCTGGGAAGA GATTAGGCGG TTGGCGGCCG ACTTCCAGCG GGCGCAGTTC 
GCCGAGGCCA CGCAGAGGTT GTCCGAGCGG AACTGCATTG AGATTGTTAA TAAATTGATT 
GCTCAGAAAC AGCTAGAAGT AGTTCATACA CTCGATGGAA AGGAATATAT TACTCCAGCC 
CAAATTAGTA AAGAAATGAG AGATGAGCTA CATGTCCGAG GTGGTCGAGT AAACATTGTT 
GATCTACAAC AGGTAATTAA TGTGGACCTG ATTCATATTG AAAATAGAAT TGGTGACATT 
ATTAAATCAG AAAAGCATGT TCAGTTAGTG TTGGGACAAC TGATAGATGA GAATTATTTG 
GATCGGTTGG CAGAAGAGGT CAATGATAAA TTGCAAGAAA GTGGTCAGGT CACCATATCA 
GAACTGTGTA AAACTTATGA TCTTCCTGGG AACTTTCTGA CACAGGCACT AACTCAGCGA 
CTTGGTAGAA TTATCAGTGG ACATATTGAT CTTGATAATA GAGGAGTAAT TTTTACGGAA 
GCTTTTGTAG CTCGACATAA AGCACGTATC CGTGGACTAT TCAGTGCTAT TACCCGGCCT 
ACAGCTGTGA ATTCTTTGAT TTCAAAATAT GGATTTCAGG AGCAGCTTCT TTACTCTGTG 
CTTGAGGAAC TTGTTAATAG CGGACGCTTA CGAGGCACTG TGGTTGGTGG GAGACAGGAT 
AAAGCTGTGT TTGTCCCTGA CATCTACTCC AGGACACAGA GTACTTGGGT GGATTCCTTT 
TTCAGGCAGA ATGGCTATCT AGAATTTGAT GCTTTGTCCA GACTTGGAAT CCCAGATGCT 
GTAAGCTACA TAAAGAAAAG ATATAAGACT ACACAACTCT TGTTTTTGAA AGCAGCTTGT 
GTTGGTCAAG GACTTGTGGA TCAAGTGGAA GCATCAGTAG AAGAAGCCAT CAGCTCTGGA 
ACATGGGTTG ATATTGCACC TCTGCTACCC ACTTCTTTAT CAGTTGAAGA TGCTGCCATA 
TTGCTTCAGC AGGTGATGAG GGCATTCAGC AAACAGGCCT CAACTGTAGT CTTTAGCGAC 
ACTGTTGTAG TCAGTGAAAA ATTTATAAAT GACTGTACAG AACTGTTCCG TGAGCTGATG 
CACCAGAAAG CTGAAAAGGA AATGAAAAAT AATCCTGTGC ATTTAATCAC TGAAGAAGAT 
CTGAAACAAA TCTCCACTTT AGAAAGCGTT AGTACAAGTA AAAAGGATAA AAAAGATGAG 
CGAAGAAGGA AAGCAACAGA GGGCAGTGGA AGCATGAGAG GAGGAGGTGG GGGCAATGCC 
AGAGAGTACA AAATTAAAAA AGTCAAGAAG AAAGGAAGAA AAGATGATGA TAGTGATGAT 
GAATCTCAAT CATCCCACAC TGGAAAGAAG AAGCCAGAGA TCAGTTTTAT GTTCCAGGAT 
GAGATTGAAG ATTTTTTAAG AAAACACATA CAAGATGCCC CTGAGGAGTT TATTTCGGAA 
CTTGCTGAGT ACTTAATAAA ACCTCTTAAT AAAACTTATC TCGAGGTGGT ACGTTCAGTA 
TTCATGTCTT CAACAACTTC TGCTTCTGGG ACGGGCAGAA AACGCACAAT CAAGGACTTG 
CAAGAAGAAG TTTCAAACCT GTACAATAAC ATTAGGTTAT TTGAAAAAGG GATGAAGTTT 
TTTGCAGATG ACACACAGGC TGCTCTTACC AAACACTTGC TGAAGTCAGT GTGTACTGAT 
ATCACTAACC TCATTTTCAA CTTCTTAGCT TCGGATTTAA TGATGGCAGT AGACGATCCT 
GCAGCCATTA CAAGTGAAAT AAGAAAGAAA ATTTTAAGTA AATTATCAGA AGAAACCAAA 
GTAGCTCTTA CAAAACTCCA TAACTCTCTG AATGAAAAGA GCATAGAAGA CTTTATTTCT 
TGTCTGGATT CTGCAGCAGA AGCTTGTGAT ATTATGGTGA AAAGGGGAGA CAAAAAAAGG 
GAAAGACAGA TACTGTTCCA ACATCGACAA GCACTGGCTG AACAGCTAAA GGTCACAGAA 
GACCCTGCTC TTATTCTGCA CCTCACATCA GTCCTGTTGT TTCAGTTTTC AACCCACAGC 
ATGCTCCATG CACCTGGAAG ATGTGTCCCA CAGATCATTG CTTTTCTTAA TAGTAAAATT 
CCAGAGGATC AGCATGCTCT TTTGGTAAAG TATCAAGGTT TGGTTGTAAA GCAGCTAGTC 
AGTCAAAGTA AGAAGACTGG GCAGGGAGAT TATCCCTTGA ATAATGAATT AGACAAAGAA 
CAAGAAGATG TTGCCAGTAC TACTCGTAAA GAGCTTCAAG AACTTTCTTC ATCCATTAAA 
GACCTTGTTC TCAAATCTAG GAAATCATCT GTGACGGAAG AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056138.1
CDS	49..2433
Translation	MADAWEEIRRLAADFQRAQFAEATQRLSERNCIEIVNKLIAQKQLEVVHTLDGKEYITPAQISKEMRDELHVRGGRVNIVDLQQVINVDLIHIENRIGDIIKSEKHVQLVLGQLIDENYLDRLAEEVNDKLQESGQVTISELCKTYDLPGNFLTQALTQRLGRIISGHIDLDNRGVIFTEAFVARHKARIRGLFSAITRPTAVNSLISKYGFQEQLLYSVLEELVNSGRLRGTVVGGRQDKAVFVPDIYSRTQSTWVDSFFRQNGYLEFDALSRLGIPDAVSYIKKRYKTTQLLFLKAACVGQGLVDQVEASVEEAISSGTWVDIAPLLPTSLSVEDAAILLQQVMRAFSKQASTVVFSDTVVVSEKFINDCTELFRELMHQKAEKEMKNNPVHLITEEDLKQISTLESVSTSKKDKKDERRRKATEGSGSMRGGGGGNAREYKIKKVKKKGRKDDDSDDESQSSHTGKKKPEISFMFQDEIEDFLRKHIQDAPEEFISELAEYLIKPLNKTYLEVVRSVFMSSTTSASGTGRKRTIKDLQEEVSNLYNNIRLFEKGMKFFADDTQAALTKHLLKSVCTDITNLIFNFLASDLMMAVDDPAAITSEIRKKILSKLSEETKVALTKLHNSLNEKSIEDFISCLDSAAEACDIMVKRGDKKRERQILFQHRQALAEQLKVTEDPALILHLTSVLLFQFSTHSMLHAPGRCVPQIIAFLNSKIPEDQHALLVKYQGLVVKQLVSQSKKTGQGDYPLNNELDKEQEDVASTTRKELQELSSSIKDLVLKSRKSSVTEE

Target ORF information:

RefSeq Version	NM_015323.4
Organism	Homo sapiens(human)
Definition	Homo sapiens UFM1 specific ligase 1 (UFL1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015323.4

ORF Insert Sequence:

ATGGCGGACG CCTGGGAAGA GATTAGGCGG TTGGCGGCCG ACTTCCAGCG GGCGCAGTTC 
GCCGAGGCCA CGCAGAGGTT GTCCGAGCGG AACTGCATTG AGATTGTTAA TAAATTGATT 
GCTCAGAAAC AGCTAGAAGT AGTTCATACA CTCGATGGAA AGGAATATAT TACTCCAGCC 
CAAATTAGTA AAGAAATGAG AGATGAGCTA CATGTCCGAG GTGGTCGAGT AAACATTGTT 
GATCTACAAC AGGTAATTAA TGTGGACCTG ATTCATATTG AAAATAGAAT TGGTGACATT 
ATTAAATCAG AAAAGCATGT TCAGTTAGTG TTGGGACAAC TGATAGATGA GAATTATTTG 
GATCGGTTGG CAGAAGAGGT CAATGATAAA TTGCAAGAAA GTGGTCAGGT CACCATATCA 
GAACTGTGTA AAACTTATGA TCTTCCTGGG AACTTTCTGA CACAGGCACT AACTCAGCGA 
CTTGGTAGAA TTATCAGTGG ACATATTGAT CTTGATAATA GAGGAGTAAT TTTTACGGAA 
GCTTTTGTAG CTCGACATAA AGCACGTATC CGTGGACTAT TCAGTGCTAT TACCCGGCCT 
ACAGCTGTGA ATTCTTTGAT TTCAAAATAT GGATTTCAGG AGCAGCTTCT TTACTCTGTG 
CTTGAGGAAC TTGTTAATAG CGGACGCTTA CGAGGCACTG TGGTTGGTGG GAGACAGGAT 
AAAGCTGTGT TTGTCCCTGA CATCTACTCC AGGACACAGA GTACTTGGGT GGATTCCTTT 
TTCAGGCAGA ATGGCTATCT AGAATTTGAT GCTTTGTCCA GACTTGGAAT CCCAGATGCT 
GTAAGCTACA TAAAGAAAAG ATATAAGACT ACACAACTCT TGTTTTTGAA AGCAGCTTGT 
GTTGGTCAAG GACTTGTGGA TCAAGTGGAA GCATCAGTAG AAGAAGCCAT CAGCTCTGGA 
ACATGGGTTG ATATTGCACC TCTGCTACCC ACTTCTTTAT CAGTTGAAGA TGCTGCCATA 
TTGCTTCAGC AGGTGATGAG GGCATTCAGC AAACAGGCCT CAACTGTAGT CTTTAGCGAC 
ACTGTTGTAG TCAGTGAAAA ATTTATAAAT GACTGTACAG AACTGTTCCG TGAGCTGATG 
CACCAGAAAG CTGAAAAGGA AATGAAAAAT AATCCTGTGC ATTTAATCAC TGAAGAAGAT 
CTGAAACAAA TCTCCACTTT AGAAAGCGTT AGTACAAGTA AAAAGGATAA AAAAGATGAG 
CGAAGAAGGA AAGCAACAGA GGGCAGTGGA AGCATGAGAG GAGGAGGTGG GGGCAATGCC 
AGAGAGTACA AAATTAAAAA AGTCAAGAAG AAAGGAAGAA AAGATGATGA TAGTGATGAT 
GAATCTCAAT CATCCCACAC TGGAAAGAAG AAGCCAGAGA TCAGTTTTAT GTTCCAGGAT 
GAGATTGAAG ATTTTTTAAG AAAACACATA CAAGATGCCC CTGAGGAGTT TATTTCGGAA 
CTTGCTGAGT ACTTAATAAA ACCTCTTAAT AAAACTTATC TCGAGGTGGT ACGTTCAGTA 
TTCATGTCTT CAACAACTTC TGCTTCTGGG ACGGGCAGAA AACGCACAAT CAAGGACTTG 
CAAGAAGAAG TTTCAAACCT GTACAATAAC ATTAGGTTAT TTGAAAAAGG GATGAAGTTT 
TTTGCAGATG ACACACAGGC TGCTCTTACC AAACACTTGC TGAAGTCAGT GTGTACTGAT 
ATCACTAACC TCATTTTCAA CTTCTTAGCT TCGGATTTAA TGATGGCAGT AGACGATCCT 
GCAGCCATTA CAAGTGAAAT AAGAAAGAAA ATTTTAAGTA AATTATCAGA AGAAACCAAA 
GTAGCTCTTA CAAAACTCCA TAACTCTCTG AATGAAAAGA GCATAGAAGA CTTTATTTCT 
TGTCTGGATT CTGCAGCAGA AGCTTGTGAT ATTATGGTGA AAAGGGGAGA CAAAAAAAGG 
GAAAGACAGA TACTGTTCCA ACATCGACAA GCACTGGCTG AACAGCTAAA GGTCACAGAA 
GACCCTGCTC TTATTCTGCA CCTCACATCA GTCCTGTTGT TTCAGTTTTC AACCCACAGC 
ATGCTCCATG CACCTGGAAG ATGTGTCCCA CAGATCATTG CTTTTCTTAA TAGTAAAATT 
CCAGAGGATC AGCATGCTCT TTTGGTAAAG TATCAAGGTT TGGTTGTAAA GCAGCTAGTC 
AGTCAAAGTA AGAAGACTGG GCAGGGAGAT TATCCCTTGA ATAATGAATT AGACAAAGAA 
CAAGAAGATG TTGCCAGTAC TACTCGTAAA GAGCTTCAAG AACTTTCTTC ATCCATTAAA 
GACCTTGTTC TCAAATCTAG GAAATCATCT GTGACGGAAG AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UFL1 ( NM_015323.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_056138.1 Homo sapiens UFM1 specific ligase 1 (UFL1), mRNA.

Price & Availability↑

CloneID	OHu24870
Clone ID Related Accession (Same CDS sequence)	NM_015323.4 , NM_015323.5
Accession Version	NM_015323.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2385bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-08
Organism	Homo sapiens(human)
Product	E3 UFM1-protein ligase 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL590404.5, BP337693.1, AB018319.1 and BC028608.1. On Nov 23, 2018 this sequence version replaced NM_015323.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC036379.2, SRR1660803.203761.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000369278.5/ ENSP00000358283.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGACG CCTGGGAAGA GATTAGGCGG TTGGCGGCCG ACTTCCAGCG GGCGCAGTTC 
GCCGAGGCCA CGCAGAGGTT GTCCGAGCGG AACTGCATTG AGATTGTTAA TAAATTGATT 
GCTCAGAAAC AGCTAGAAGT AGTTCATACA CTCGATGGAA AGGAATATAT TACTCCAGCC 
CAAATTAGTA AAGAAATGAG AGATGAGCTA CATGTCCGAG GTGGTCGAGT AAACATTGTT 
GATCTACAAC AGGTAATTAA TGTGGACCTG ATTCATATTG AAAATAGAAT TGGTGACATT 
ATTAAATCAG AAAAGCATGT TCAGTTAGTG TTGGGACAAC TGATAGATGA GAATTATTTG 
GATCGGTTGG CAGAAGAGGT CAATGATAAA TTGCAAGAAA GTGGTCAGGT CACCATATCA 
GAACTGTGTA AAACTTATGA TCTTCCTGGG AACTTTCTGA CACAGGCACT AACTCAGCGA 
CTTGGTAGAA TTATCAGTGG ACATATTGAT CTTGATAATA GAGGAGTAAT TTTTACGGAA 
GCTTTTGTAG CTCGACATAA AGCACGTATC CGTGGACTAT TCAGTGCTAT TACCCGGCCT 
ACAGCTGTGA ATTCTTTGAT TTCAAAATAT GGATTTCAGG AGCAGCTTCT TTACTCTGTG 
CTTGAGGAAC TTGTTAATAG CGGACGCTTA CGAGGCACTG TGGTTGGTGG GAGACAGGAT 
AAAGCTGTGT TTGTCCCTGA CATCTACTCC AGGACACAGA GTACTTGGGT GGATTCCTTT 
TTCAGGCAGA ATGGCTATCT AGAATTTGAT GCTTTGTCCA GACTTGGAAT CCCAGATGCT 
GTAAGCTACA TAAAGAAAAG ATATAAGACT ACACAACTCT TGTTTTTGAA AGCAGCTTGT 
GTTGGTCAAG GACTTGTGGA TCAAGTGGAA GCATCAGTAG AAGAAGCCAT CAGCTCTGGA 
ACATGGGTTG ATATTGCACC TCTGCTACCC ACTTCTTTAT CAGTTGAAGA TGCTGCCATA 
TTGCTTCAGC AGGTGATGAG GGCATTCAGC AAACAGGCCT CAACTGTAGT CTTTAGCGAC 
ACTGTTGTAG TCAGTGAAAA ATTTATAAAT GACTGTACAG AACTGTTCCG TGAGCTGATG 
CACCAGAAAG CTGAAAAGGA AATGAAAAAT AATCCTGTGC ATTTAATCAC TGAAGAAGAT 
CTGAAACAAA TCTCCACTTT AGAAAGCGTT AGTACAAGTA AAAAGGATAA AAAAGATGAG 
CGAAGAAGGA AAGCAACAGA GGGCAGTGGA AGCATGAGAG GAGGAGGTGG GGGCAATGCC 
AGAGAGTACA AAATTAAAAA AGTCAAGAAG AAAGGAAGAA AAGATGATGA TAGTGATGAT 
GAATCTCAAT CATCCCACAC TGGAAAGAAG AAGCCAGAGA TCAGTTTTAT GTTCCAGGAT 
GAGATTGAAG ATTTTTTAAG AAAACACATA CAAGATGCCC CTGAGGAGTT TATTTCGGAA 
CTTGCTGAGT ACTTAATAAA ACCTCTTAAT AAAACTTATC TCGAGGTGGT ACGTTCAGTA 
TTCATGTCTT CAACAACTTC TGCTTCTGGG ACGGGCAGAA AACGCACAAT CAAGGACTTG 
CAAGAAGAAG TTTCAAACCT GTACAATAAC ATTAGGTTAT TTGAAAAAGG GATGAAGTTT 
TTTGCAGATG ACACACAGGC TGCTCTTACC AAACACTTGC TGAAGTCAGT GTGTACTGAT 
ATCACTAACC TCATTTTCAA CTTCTTAGCT TCGGATTTAA TGATGGCAGT AGACGATCCT 
GCAGCCATTA CAAGTGAAAT AAGAAAGAAA ATTTTAAGTA AATTATCAGA AGAAACCAAA 
GTAGCTCTTA CAAAACTCCA TAACTCTCTG AATGAAAAGA GCATAGAAGA CTTTATTTCT 
TGTCTGGATT CTGCAGCAGA AGCTTGTGAT ATTATGGTGA AAAGGGGAGA CAAAAAAAGG 
GAAAGACAGA TACTGTTCCA ACATCGACAA GCACTGGCTG AACAGCTAAA GGTCACAGAA 
GACCCTGCTC TTATTCTGCA CCTCACATCA GTCCTGTTGT TTCAGTTTTC AACCCACAGC 
ATGCTCCATG CACCTGGAAG ATGTGTCCCA CAGATCATTG CTTTTCTTAA TAGTAAAATT 
CCAGAGGATC AGCATGCTCT TTTGGTAAAG TATCAAGGTT TGGTTGTAAA GCAGCTAGTC 
AGTCAAAGTA AGAAGACTGG GCAGGGAGAT TATCCCTTGA ATAATGAATT AGACAAAGAA 
CAAGAAGATG TTGCCAGTAC TACTCGTAAA GAGCTTCAAG AACTTTCTTC ATCCATTAAA 
GACCTTGTTC TCAAATCTAG GAAATCATCT GTGACGGAAG AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056138.1
CDS	69..2453
Translation	MADAWEEIRRLAADFQRAQFAEATQRLSERNCIEIVNKLIAQKQLEVVHTLDGKEYITPAQISKEMRDELHVRGGRVNIVDLQQVINVDLIHIENRIGDIIKSEKHVQLVLGQLIDENYLDRLAEEVNDKLQESGQVTISELCKTYDLPGNFLTQALTQRLGRIISGHIDLDNRGVIFTEAFVARHKARIRGLFSAITRPTAVNSLISKYGFQEQLLYSVLEELVNSGRLRGTVVGGRQDKAVFVPDIYSRTQSTWVDSFFRQNGYLEFDALSRLGIPDAVSYIKKRYKTTQLLFLKAACVGQGLVDQVEASVEEAISSGTWVDIAPLLPTSLSVEDAAILLQQVMRAFSKQASTVVFSDTVVVSEKFINDCTELFRELMHQKAEKEMKNNPVHLITEEDLKQISTLESVSTSKKDKKDERRRKATEGSGSMRGGGGGNAREYKIKKVKKKGRKDDDSDDESQSSHTGKKKPEISFMFQDEIEDFLRKHIQDAPEEFISELAEYLIKPLNKTYLEVVRSVFMSSTTSASGTGRKRTIKDLQEEVSNLYNNIRLFEKGMKFFADDTQAALTKHLLKSVCTDITNLIFNFLASDLMMAVDDPAAITSEIRKKILSKLSEETKVALTKLHNSLNEKSIEDFISCLDSAAEACDIMVKRGDKKRERQILFQHRQALAEQLKVTEDPALILHLTSVLLFQFSTHSMLHAPGRCVPQIIAFLNSKIPEDQHALLVKYQGLVVKQLVSQSKKTGQGDYPLNNELDKEQEDVASTTRKELQELSSSIKDLVLKSRKSSVTEE

Target ORF information:

RefSeq Version	NM_015323.5
Organism	Homo sapiens(human)
Definition	Homo sapiens UFM1 specific ligase 1 (UFL1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015323.5

ORF Insert Sequence:

ATGGCGGACG CCTGGGAAGA GATTAGGCGG TTGGCGGCCG ACTTCCAGCG GGCGCAGTTC 
GCCGAGGCCA CGCAGAGGTT GTCCGAGCGG AACTGCATTG AGATTGTTAA TAAATTGATT 
GCTCAGAAAC AGCTAGAAGT AGTTCATACA CTCGATGGAA AGGAATATAT TACTCCAGCC 
CAAATTAGTA AAGAAATGAG AGATGAGCTA CATGTCCGAG GTGGTCGAGT AAACATTGTT 
GATCTACAAC AGGTAATTAA TGTGGACCTG ATTCATATTG AAAATAGAAT TGGTGACATT 
ATTAAATCAG AAAAGCATGT TCAGTTAGTG TTGGGACAAC TGATAGATGA GAATTATTTG 
GATCGGTTGG CAGAAGAGGT CAATGATAAA TTGCAAGAAA GTGGTCAGGT CACCATATCA 
GAACTGTGTA AAACTTATGA TCTTCCTGGG AACTTTCTGA CACAGGCACT AACTCAGCGA 
CTTGGTAGAA TTATCAGTGG ACATATTGAT CTTGATAATA GAGGAGTAAT TTTTACGGAA 
GCTTTTGTAG CTCGACATAA AGCACGTATC CGTGGACTAT TCAGTGCTAT TACCCGGCCT 
ACAGCTGTGA ATTCTTTGAT TTCAAAATAT GGATTTCAGG AGCAGCTTCT TTACTCTGTG 
CTTGAGGAAC TTGTTAATAG CGGACGCTTA CGAGGCACTG TGGTTGGTGG GAGACAGGAT 
AAAGCTGTGT TTGTCCCTGA CATCTACTCC AGGACACAGA GTACTTGGGT GGATTCCTTT 
TTCAGGCAGA ATGGCTATCT AGAATTTGAT GCTTTGTCCA GACTTGGAAT CCCAGATGCT 
GTAAGCTACA TAAAGAAAAG ATATAAGACT ACACAACTCT TGTTTTTGAA AGCAGCTTGT 
GTTGGTCAAG GACTTGTGGA TCAAGTGGAA GCATCAGTAG AAGAAGCCAT CAGCTCTGGA 
ACATGGGTTG ATATTGCACC TCTGCTACCC ACTTCTTTAT CAGTTGAAGA TGCTGCCATA 
TTGCTTCAGC AGGTGATGAG GGCATTCAGC AAACAGGCCT CAACTGTAGT CTTTAGCGAC 
ACTGTTGTAG TCAGTGAAAA ATTTATAAAT GACTGTACAG AACTGTTCCG TGAGCTGATG 
CACCAGAAAG CTGAAAAGGA AATGAAAAAT AATCCTGTGC ATTTAATCAC TGAAGAAGAT 
CTGAAACAAA TCTCCACTTT AGAAAGCGTT AGTACAAGTA AAAAGGATAA AAAAGATGAG 
CGAAGAAGGA AAGCAACAGA GGGCAGTGGA AGCATGAGAG GAGGAGGTGG GGGCAATGCC 
AGAGAGTACA AAATTAAAAA AGTCAAGAAG AAAGGAAGAA AAGATGATGA TAGTGATGAT 
GAATCTCAAT CATCCCACAC TGGAAAGAAG AAGCCAGAGA TCAGTTTTAT GTTCCAGGAT 
GAGATTGAAG ATTTTTTAAG AAAACACATA CAAGATGCCC CTGAGGAGTT TATTTCGGAA 
CTTGCTGAGT ACTTAATAAA ACCTCTTAAT AAAACTTATC TCGAGGTGGT ACGTTCAGTA 
TTCATGTCTT CAACAACTTC TGCTTCTGGG ACGGGCAGAA AACGCACAAT CAAGGACTTG 
CAAGAAGAAG TTTCAAACCT GTACAATAAC ATTAGGTTAT TTGAAAAAGG GATGAAGTTT 
TTTGCAGATG ACACACAGGC TGCTCTTACC AAACACTTGC TGAAGTCAGT GTGTACTGAT 
ATCACTAACC TCATTTTCAA CTTCTTAGCT TCGGATTTAA TGATGGCAGT AGACGATCCT 
GCAGCCATTA CAAGTGAAAT AAGAAAGAAA ATTTTAAGTA AATTATCAGA AGAAACCAAA 
GTAGCTCTTA CAAAACTCCA TAACTCTCTG AATGAAAAGA GCATAGAAGA CTTTATTTCT 
TGTCTGGATT CTGCAGCAGA AGCTTGTGAT ATTATGGTGA AAAGGGGAGA CAAAAAAAGG 
GAAAGACAGA TACTGTTCCA ACATCGACAA GCACTGGCTG AACAGCTAAA GGTCACAGAA 
GACCCTGCTC TTATTCTGCA CCTCACATCA GTCCTGTTGT TTCAGTTTTC AACCCACAGC 
ATGCTCCATG CACCTGGAAG ATGTGTCCCA CAGATCATTG CTTTTCTTAA TAGTAAAATT 
CCAGAGGATC AGCATGCTCT TTTGGTAAAG TATCAAGGTT TGGTTGTAAA GCAGCTAGTC 
AGTCAAAGTA AGAAGACTGG GCAGGGAGAT TATCCCTTGA ATAATGAATT AGACAAAGAA 
CAAGAAGATG TTGCCAGTAC TACTCGTAAA GAGCTTCAAG AACTTTCTTC ATCCATTAAA 
GACCTTGTTC TCAAATCTAG GAAATCATCT GTGACGGAAG AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Modification of ASC1 by UFM1 is crucial for ER? transactivation and breast cancer development.
Molecular cell56(2)261-74(2014 Oct)
Yoo HM,Kang SH,Kim JY,Lee JE,Seong MW,Lee SW,Ka SH,Sou YS,Komatsu M,Tanaka K,Lee ST,Noh DY,Baek SH,Jeon YJ,Chung CH

Overexpression of a novel regulator of p120 catenin, NLBP, promotes lung adenocarcinoma proliferation.
Cell cycle (Georgetown, Tex.)12(15)2443-53(2013 Aug)
Kim CH,Nam HS,Lee EH,Han SH,Cho HJ,Chung HJ,Lee NS,Choi SJ,Kim H,Ryu JS,Kwon J,Kim H

Transcriptional regulation of the Ufm1 conjugation system in response to disturbance of the endoplasmic reticulum homeostasis and inhibition of vesicle trafficking.
PloS one7(11)e48587(2012)
Zhang Y,Zhang M,Wu J,Lei G,Li H

Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity.
The EMBO journal29(14)2446-60(2010 Jul)
Shiwaku H,Yoshimura N,Tamura T,Sone M,Ogishima S,Watase K,Tagawa K,Okazawa H

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UFL1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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