FMR1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FMR1
Entrez Gene ID	2332
Full Name	fragile X mental retardation 1
Synonyms	FMRP,FRAXA,POF,POF1
General protein information	Preferred Names fragile X mental retardation 1 Names synaptic functional regulator FMR1 fragile X mental retardation protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq27.3
Summary	The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010].
Disorder MIM:	309550
Disorder Html:	Fragile X syndrome, 300624 (3); Fragile X tremor/ataxia syndrome, 300623 (3); Premature ovarian failure 1, 311360 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001185081.1	NP_001172010.1	synaptic functional regulator FMR1 isoform ISO12
NM_002024.5	NP_002015.1	synaptic functional regulator FMR1 isoform ISO1
NM_001185076.1	NP_001172005.1	synaptic functional regulator FMR1 isoform ISO7
NM_001185082.2	NP_001172011.1	synaptic functional regulator FMR1 isoform ISO9
NM_001185081.2	NP_001172010.1	synaptic functional regulator FMR1 isoform ISO12
NM_002024.6	NP_002015.1	synaptic functional regulator FMR1 isoform ISO1
NM_001185075.1	NP_001172004.1	synaptic functional regulator FMR1 isoform ISO6
NM_001185082.1	NP_001172011.1	synaptic functional regulator FMR1 isoform ISO9

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	Fmr1	NP_731444.1
Pan troglodytes (chimpanzee)	FMR1	XP_521294.3
Canis lupus familiaris (dog)	FMR1	XP_866618.1
Mus musculus (house mouse)	Fmr1	NP_032057.2
Homo sapiens (human)	FMR1	NP_002015.1
	FMR1	XP_001087617.2
Danio rerio (zebrafish)	fmr1	NP_694495.1
Xenopus tropicalis (tropical clawed frog)	fmr1	NP_001005454.1
Rattus norvegicus (Norway rat)	Fmr1	NP_434691.1
Gallus gallus (chicken)	FMR1	XP_420363.1
Bos taurus (cattle)	FMR1	NP_001179079.1

Gene Ontology
Bibliography

Related articles in PubMed

Alternative splicing of exon 14 determines nuclear or cytoplasmic localisation of fmr1 protein isoforms.
Sittler A, Devys D, Weber C, Mandel JL
Human molecular genetics5(1)95-102(1996 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Fmr1 knockout (KO) mice show widespread changes in histone marks as well as transcriptional misregulation resulting in increased expression of many critical synaptic genes. Data suggest that one chromatin target of FMRP, the reader protein Brd4, appears to be significantly involved in this transcriptional disruption.
Title: Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition.

Cerebellar and brainstem volumes were likely affected during both development and progression of neurodegeneration in premutation carriers of FMR1.
Title: Abnormal trajectories in cerebellum and brainstem volumes in carriers of the fragile X premutation.

The primary objective of this review is to familiarize reproductive health care providers including reproductive endocrinology and infertility specialists with the different phenotypes encompassing FMR1 premutation carriers
Title: Fragile X premutation in women: recognizing the health challenges beyond primary ovarian insufficiency.

Our data strongly support a gain-of-function pathogenic mechanism of PQBP1 c.459_462delAGAG and c.463_464dupAG mutations, and suggest that therapeutic strategies to restore FMRP function may be beneficial for those patients
Title: Mutations of PQBP1 in Renpenning syndrome promote ubiquitin-mediated degradation of FMRP and cause synaptic dysfunction.

Expression of FMRpolyG is pathogenic, while the sole expression of CGG RNA is not. FMRpolyG interacts with the nuclear lamina protein LAP2beta and disorganizes the nuclear lamina architecture in neurons differentiated from FXTAS iPS cells. Finally, expression of LAP2beta rescues neuronal death induced by FMRpolyG.
Title: Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome.

The following FMR1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FMR1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu21442	NM_002024.6 Latest version!	Homo sapiens FMRP translational regulator 1 (FMR1), transcript variant ISO1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu21881	NM_001185075.1 Latest version!	Homo sapiens FMRP translational regulator 1 (FMR1), transcript variant ISO6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu20575	NM_001185082.2 Latest version!	Homo sapiens FMRP translational regulator 1 (FMR1), transcript variant ISO9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu21356	NM_001185076.1 Latest version!	Homo sapiens FMRP translational regulator 1 (FMR1), transcript variant ISO7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu21769	NM_001185081.2 Latest version!	Homo sapiens FMRP translational regulator 1 (FMR1), transcript variant ISO12, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$300.30 $429.00
View Old Accession Versions >>
OHu21769	NM_001185081.1	Homo sapiens fragile X mental retardation 1 (FMR1), transcript variant ISO12, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$300.30 $429.00
OHu21442	NM_002024.5	Homo sapiens fragile X mental retardation 1 (FMR1), transcript variant ISO1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu20575	NM_001185082.1	Homo sapiens fragile X mental retardation 1 (FMR1), transcript variant ISO9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FMR1 ( NM_002024.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_002015.1 Homo sapiens fragile X mental retardation 1 (FMR1), transcript variant ISO1, mRNA.

Price & Availability↑

CloneID	OHu21442
Clone ID Related Accession (Same CDS sequence)	NM_002024.5 , NM_002024.6
Accession Version	NM_002024.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1899bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-06
Organism	Homo sapiens(human)
Product	synaptic functional regulator FMR1 isoform ISO1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC086957.1, X69962.1 and L29074.1. This sequence is a reference standard in the RefSeqGene project. On Jun 3, 2010 this sequence version replaced NM_002024.4. Transcript Variant: This variant (ISO1) represents the longest transcript and it encodes the longest protein (isoform ISO1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: KJ534837.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGC TGGTGGTGGA AGTGCGGGGC TCCAATGGCG CTTTCTACAA GGCATTTGTA 
AAGGATGTTC ATGAAGATTC AATAACAGTT GCATTTGAAA ACAACTGGCA GCCTGATAGG 
CAGATTCCAT TTCATGATGT CAGATTCCCA CCTCCTGTAG GTTATAATAA AGATATAAAT 
GAAAGTGATG AAGTTGAGGT GTATTCCAGA GCAAATGAAA AAGAGCCTTG CTGTTGGTGG 
TTAGCTAAAG TGAGGATGAT AAAGGGTGAG TTTTATGTGA TAGAATATGC AGCATGTGAT 
GCAACTTACA ATGAAATTGT CACAATTGAA CGTCTAAGAT CTGTTAATCC CAACAAACCT 
GCCACAAAAG ATACTTTCCA TAAGATCAAG CTGGATGTGC CAGAAGACTT ACGGCAAATG 
TGTGCCAAAG AGGCGGCACA TAAGGATTTT AAAAAGGCAG TTGGTGCCTT TTCTGTAACT 
TATGATCCAG AAAATTATCA GCTTGTCATT TTGTCCATCA ATGAAGTCAC CTCAAAGCGA 
GCACATATGC TGATTGACAT GCACTTTCGG AGTCTGCGCA CTAAGTTGTC TCTGATAATG 
AGAAATGAAG AAGCTAGTAA GCAGCTGGAG AGTTCAAGGC AGCTTGCCTC GAGATTTCAT 
GAACAGTTTA TCGTAAGAGA AGATCTGATG GGTCTAGCTA TTGGTACTCA TGGTGCTAAT 
ATTCAGCAAG CTAGAAAAGT ACCTGGGGTC ACTGCTATTG ATCTAGATGA AGATACCTGC 
ACATTTCATA TTTATGGAGA GGATCAGGAT GCAGTGAAAA AAGCTAGAAG CTTTCTCGAA 
TTTGCTGAAG ATGTAATACA AGTTCCAAGG AACTTAGTAG GCAAAGTAAT AGGAAAAAAT 
GGAAAGCTGA TTCAGGAGAT TGTGGACAAG TCAGGAGTTG TGAGGGTGAG GATTGAGGCT 
GAAAATGAGA AAAATGTTCC ACAAGAAGAG GAAATTATGC CACCAAATTC CCTTCCTTCC 
AATAATTCAA GGGTTGGACC TAATGCCCCA GAAGAAAAAA AACATTTAGA TATAAAGGAA 
AACAGCACCC ATTTTTCTCA ACCTAACAGT ACAAAAGTCC AGAGGGTGTT AGTGGCTTCA 
TCAGTTGTAG CAGGGGAATC CCAGAAACCT GAACTCAAGG CTTGGCAGGG TATGGTACCA 
TTTGTTTTTG TGGGAACAAA GGACAGCATC GCTAATGCCA CTGTTCTTTT GGATTATCAC 
CTGAACTATT TAAAGGAAGT AGACCAGTTG CGTTTGGAGA GATTACAAAT TGATGAGCAG 
TTGCGACAGA TTGGAGCTAG TTCTAGACCA CCACCAAATC GTACAGATAA GGAAAAAAGC 
TATGTGACTG ATGATGGTCA AGGAATGGGT CGAGGTAGTA GACCTTACAG AAATAGGGGG 
CACGGCAGAC GCGGTCCTGG ATATACTTCA GGAACTAATT CTGAAGCATC AAATGCTTCT 
GAAACAGAAT CTGACCACAG AGACGAACTC AGTGATTGGT CATTAGCTCC AACAGAGGAA 
GAGAGGGAGA GCTTCCTGCG CAGAGGAGAC GGACGGCGGC GTGGAGGGGG AGGAAGAGGA 
CAAGGAGGAA GAGGACGTGG AGGAGGCTTC AAAGGAAACG ACGATCACTC CCGAACAGAT 
AATCGTCCAC GTAATCCAAG AGAGGCTAAA GGAAGAACAA CAGATGGATC CCTTCAGATC 
AGAGTTGACT GCAATAATGA AAGGAGTGTC CACACTAAAA CATTACAGAA TACCTCCAGT 
GAAGGTAGTC GGCTGCGCAC GGGTAAAGAT CGTAACCAGA AGAAAGAGAA GCCAGACAGC 
GTGGATGGTC AGCAACCACT CGTGAATGGA GTACCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002015.1
CDS	230..2128
Translation	MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKENSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYHLNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRGHGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRGQGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSSEGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP

Target ORF information:

RefSeq Version	NM_002024.5
Organism	Homo sapiens(human)
Definition	Homo sapiens fragile X mental retardation 1 (FMR1), transcript variant ISO1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002024.5

ORF Insert Sequence:

ATGGAGGAGC TGGTGGTGGA AGTGCGGGGC TCCAATGGCG CTTTCTACAA GGCATTTGTA 
AAGGATGTTC ATGAAGATTC AATAACAGTT GCATTTGAAA ACAACTGGCA GCCTGATAGG 
CAGATTCCAT TTCATGATGT CAGATTCCCA CCTCCTGTAG GTTATAATAA AGATATAAAT 
GAAAGTGATG AAGTTGAGGT GTATTCCAGA GCAAATGAAA AAGAGCCTTG CTGTTGGTGG 
TTAGCTAAAG TGAGGATGAT AAAGGGTGAG TTTTATGTGA TAGAATATGC AGCATGTGAT 
GCAACTTACA ATGAAATTGT CACAATTGAA CGTCTAAGAT CTGTTAATCC CAACAAACCT 
GCCACAAAAG ATACTTTCCA TAAGATCAAG CTGGATGTGC CAGAAGACTT ACGGCAAATG 
TGTGCCAAAG AGGCGGCACA TAAGGATTTT AAAAAGGCAG TTGGTGCCTT TTCTGTAACT 
TATGATCCAG AAAATTATCA GCTTGTCATT TTGTCCATCA ATGAAGTCAC CTCAAAGCGA 
GCACATATGC TGATTGACAT GCACTTTCGG AGTCTGCGCA CTAAGTTGTC TCTGATAATG 
AGAAATGAAG AAGCTAGTAA GCAGCTGGAG AGTTCAAGGC AGCTTGCCTC GAGATTTCAT 
GAACAGTTTA TCGTAAGAGA AGATCTGATG GGTCTAGCTA TTGGTACTCA TGGTGCTAAT 
ATTCAGCAAG CTAGAAAAGT ACCTGGGGTC ACTGCTATTG ATCTAGATGA AGATACCTGC 
ACATTTCATA TTTATGGAGA GGATCAGGAT GCAGTGAAAA AAGCTAGAAG CTTTCTCGAA 
TTTGCTGAAG ATGTAATACA AGTTCCAAGG AACTTAGTAG GCAAAGTAAT AGGAAAAAAT 
GGAAAGCTGA TTCAGGAGAT TGTGGACAAG TCAGGAGTTG TGAGGGTGAG GATTGAGGCT 
GAAAATGAGA AAAATGTTCC ACAAGAAGAG GAAATTATGC CACCAAATTC CCTTCCTTCC 
AATAATTCAA GGGTTGGACC TAATGCCCCA GAAGAAAAAA AACATTTAGA TATAAAGGAA 
AACAGCACCC ATTTTTCTCA ACCTAACAGT ACAAAAGTCC AGAGGGTGTT AGTGGCTTCA 
TCAGTTGTAG CAGGGGAATC CCAGAAACCT GAACTCAAGG CTTGGCAGGG TATGGTACCA 
TTTGTTTTTG TGGGAACAAA GGACAGCATC GCTAATGCCA CTGTTCTTTT GGATTATCAC 
CTGAACTATT TAAAGGAAGT AGACCAGTTG CGTTTGGAGA GATTACAAAT TGATGAGCAG 
TTGCGACAGA TTGGAGCTAG TTCTAGACCA CCACCAAATC GTACAGATAA GGAAAAAAGC 
TATGTGACTG ATGATGGTCA AGGAATGGGT CGAGGTAGTA GACCTTACAG AAATAGGGGG 
CACGGCAGAC GCGGTCCTGG ATATACTTCA GGAACTAATT CTGAAGCATC AAATGCTTCT 
GAAACAGAAT CTGACCACAG AGACGAACTC AGTGATTGGT CATTAGCTCC AACAGAGGAA 
GAGAGGGAGA GCTTCCTGCG CAGAGGAGAC GGACGGCGGC GTGGAGGGGG AGGAAGAGGA 
CAAGGAGGAA GAGGACGTGG AGGAGGCTTC AAAGGAAACG ACGATCACTC CCGAACAGAT 
AATCGTCCAC GTAATCCAAG AGAGGCTAAA GGAAGAACAA CAGATGGATC CCTTCAGATC 
AGAGTTGACT GCAATAATGA AAGGAGTGTC CACACTAAAA CATTACAGAA TACCTCCAGT 
GAAGGTAGTC GGCTGCGCAC GGGTAAAGAT CGTAACCAGA AGAAAGAGAA GCCAGACAGC 
GTGGATGGTC AGCAACCACT CGTGAATGGA GTACCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FMR1 ( NM_002024.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_002015.1 Homo sapiens FMRP translational regulator 1 (FMR1), transcript variant ISO1, mRNA.

Price & Availability↑

CloneID	OHu21442
Clone ID Related Accession (Same CDS sequence)	NM_002024.5 , NM_002024.6
Accession Version	NM_002024.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1899bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	synaptic functional regulator FMR1 isoform ISO1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from L29074.1 and KJ534837.1. On Oct 24, 2019 this sequence version replaced NM_002024.5. Transcript Variant: This variant (ISO1) represents the longest transcript and it encodes the longest protein (isoform ISO1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: KJ534837.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGC TGGTGGTGGA AGTGCGGGGC TCCAATGGCG CTTTCTACAA GGCATTTGTA 
AAGGATGTTC ATGAAGATTC AATAACAGTT GCATTTGAAA ACAACTGGCA GCCTGATAGG 
CAGATTCCAT TTCATGATGT CAGATTCCCA CCTCCTGTAG GTTATAATAA AGATATAAAT 
GAAAGTGATG AAGTTGAGGT GTATTCCAGA GCAAATGAAA AAGAGCCTTG CTGTTGGTGG 
TTAGCTAAAG TGAGGATGAT AAAGGGTGAG TTTTATGTGA TAGAATATGC AGCATGTGAT 
GCAACTTACA ATGAAATTGT CACAATTGAA CGTCTAAGAT CTGTTAATCC CAACAAACCT 
GCCACAAAAG ATACTTTCCA TAAGATCAAG CTGGATGTGC CAGAAGACTT ACGGCAAATG 
TGTGCCAAAG AGGCGGCACA TAAGGATTTT AAAAAGGCAG TTGGTGCCTT TTCTGTAACT 
TATGATCCAG AAAATTATCA GCTTGTCATT TTGTCCATCA ATGAAGTCAC CTCAAAGCGA 
GCACATATGC TGATTGACAT GCACTTTCGG AGTCTGCGCA CTAAGTTGTC TCTGATAATG 
AGAAATGAAG AAGCTAGTAA GCAGCTGGAG AGTTCAAGGC AGCTTGCCTC GAGATTTCAT 
GAACAGTTTA TCGTAAGAGA AGATCTGATG GGTCTAGCTA TTGGTACTCA TGGTGCTAAT 
ATTCAGCAAG CTAGAAAAGT ACCTGGGGTC ACTGCTATTG ATCTAGATGA AGATACCTGC 
ACATTTCATA TTTATGGAGA GGATCAGGAT GCAGTGAAAA AAGCTAGAAG CTTTCTCGAA 
TTTGCTGAAG ATGTAATACA AGTTCCAAGG AACTTAGTAG GCAAAGTAAT AGGAAAAAAT 
GGAAAGCTGA TTCAGGAGAT TGTGGACAAG TCAGGAGTTG TGAGGGTGAG GATTGAGGCT 
GAAAATGAGA AAAATGTTCC ACAAGAAGAG GAAATTATGC CACCAAATTC CCTTCCTTCC 
AATAATTCAA GGGTTGGACC TAATGCCCCA GAAGAAAAAA AACATTTAGA TATAAAGGAA 
AACAGCACCC ATTTTTCTCA ACCTAACAGT ACAAAAGTCC AGAGGGTGTT AGTGGCTTCA 
TCAGTTGTAG CAGGGGAATC CCAGAAACCT GAACTCAAGG CTTGGCAGGG TATGGTACCA 
TTTGTTTTTG TGGGAACAAA GGACAGCATC GCTAATGCCA CTGTTCTTTT GGATTATCAC 
CTGAACTATT TAAAGGAAGT AGACCAGTTG CGTTTGGAGA GATTACAAAT TGATGAGCAG 
TTGCGACAGA TTGGAGCTAG TTCTAGACCA CCACCAAATC GTACAGATAA GGAAAAAAGC 
TATGTGACTG ATGATGGTCA AGGAATGGGT CGAGGTAGTA GACCTTACAG AAATAGGGGG 
CACGGCAGAC GCGGTCCTGG ATATACTTCA GGAACTAATT CTGAAGCATC AAATGCTTCT 
GAAACAGAAT CTGACCACAG AGACGAACTC AGTGATTGGT CATTAGCTCC AACAGAGGAA 
GAGAGGGAGA GCTTCCTGCG CAGAGGAGAC GGACGGCGGC GTGGAGGGGG AGGAAGAGGA 
CAAGGAGGAA GAGGACGTGG AGGAGGCTTC AAAGGAAACG ACGATCACTC CCGAACAGAT 
AATCGTCCAC GTAATCCAAG AGAGGCTAAA GGAAGAACAA CAGATGGATC CCTTCAGATC 
AGAGTTGACT GCAATAATGA AAGGAGTGTC CACACTAAAA CATTACAGAA TACCTCCAGT 
GAAGGTAGTC GGCTGCGCAC GGGTAAAGAT CGTAACCAGA AGAAAGAGAA GCCAGACAGC 
GTGGATGGTC AGCAACCACT CGTGAATGGA GTACCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002015.1
CDS	262..2160
Translation	MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKENSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYHLNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRGHGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRGQGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSSEGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP

Target ORF information:

RefSeq Version	NM_002024.6
Organism	Homo sapiens(human)
Definition	Homo sapiens FMRP translational regulator 1 (FMR1), transcript variant ISO1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002024.6

ORF Insert Sequence:

ATGGAGGAGC TGGTGGTGGA AGTGCGGGGC TCCAATGGCG CTTTCTACAA GGCATTTGTA 
AAGGATGTTC ATGAAGATTC AATAACAGTT GCATTTGAAA ACAACTGGCA GCCTGATAGG 
CAGATTCCAT TTCATGATGT CAGATTCCCA CCTCCTGTAG GTTATAATAA AGATATAAAT 
GAAAGTGATG AAGTTGAGGT GTATTCCAGA GCAAATGAAA AAGAGCCTTG CTGTTGGTGG 
TTAGCTAAAG TGAGGATGAT AAAGGGTGAG TTTTATGTGA TAGAATATGC AGCATGTGAT 
GCAACTTACA ATGAAATTGT CACAATTGAA CGTCTAAGAT CTGTTAATCC CAACAAACCT 
GCCACAAAAG ATACTTTCCA TAAGATCAAG CTGGATGTGC CAGAAGACTT ACGGCAAATG 
TGTGCCAAAG AGGCGGCACA TAAGGATTTT AAAAAGGCAG TTGGTGCCTT TTCTGTAACT 
TATGATCCAG AAAATTATCA GCTTGTCATT TTGTCCATCA ATGAAGTCAC CTCAAAGCGA 
GCACATATGC TGATTGACAT GCACTTTCGG AGTCTGCGCA CTAAGTTGTC TCTGATAATG 
AGAAATGAAG AAGCTAGTAA GCAGCTGGAG AGTTCAAGGC AGCTTGCCTC GAGATTTCAT 
GAACAGTTTA TCGTAAGAGA AGATCTGATG GGTCTAGCTA TTGGTACTCA TGGTGCTAAT 
ATTCAGCAAG CTAGAAAAGT ACCTGGGGTC ACTGCTATTG ATCTAGATGA AGATACCTGC 
ACATTTCATA TTTATGGAGA GGATCAGGAT GCAGTGAAAA AAGCTAGAAG CTTTCTCGAA 
TTTGCTGAAG ATGTAATACA AGTTCCAAGG AACTTAGTAG GCAAAGTAAT AGGAAAAAAT 
GGAAAGCTGA TTCAGGAGAT TGTGGACAAG TCAGGAGTTG TGAGGGTGAG GATTGAGGCT 
GAAAATGAGA AAAATGTTCC ACAAGAAGAG GAAATTATGC CACCAAATTC CCTTCCTTCC 
AATAATTCAA GGGTTGGACC TAATGCCCCA GAAGAAAAAA AACATTTAGA TATAAAGGAA 
AACAGCACCC ATTTTTCTCA ACCTAACAGT ACAAAAGTCC AGAGGGTGTT AGTGGCTTCA 
TCAGTTGTAG CAGGGGAATC CCAGAAACCT GAACTCAAGG CTTGGCAGGG TATGGTACCA 
TTTGTTTTTG TGGGAACAAA GGACAGCATC GCTAATGCCA CTGTTCTTTT GGATTATCAC 
CTGAACTATT TAAAGGAAGT AGACCAGTTG CGTTTGGAGA GATTACAAAT TGATGAGCAG 
TTGCGACAGA TTGGAGCTAG TTCTAGACCA CCACCAAATC GTACAGATAA GGAAAAAAGC 
TATGTGACTG ATGATGGTCA AGGAATGGGT CGAGGTAGTA GACCTTACAG AAATAGGGGG 
CACGGCAGAC GCGGTCCTGG ATATACTTCA GGAACTAATT CTGAAGCATC AAATGCTTCT 
GAAACAGAAT CTGACCACAG AGACGAACTC AGTGATTGGT CATTAGCTCC AACAGAGGAA 
GAGAGGGAGA GCTTCCTGCG CAGAGGAGAC GGACGGCGGC GTGGAGGGGG AGGAAGAGGA 
CAAGGAGGAA GAGGACGTGG AGGAGGCTTC AAAGGAAACG ACGATCACTC CCGAACAGAT 
AATCGTCCAC GTAATCCAAG AGAGGCTAAA GGAAGAACAA CAGATGGATC CCTTCAGATC 
AGAGTTGACT GCAATAATGA AAGGAGTGTC CACACTAAAA CATTACAGAA TACCTCCAGT 
GAAGGTAGTC GGCTGCGCAC GGGTAAAGAT CGTAACCAGA AGAAAGAGAA GCCAGACAGC 
GTGGATGGTC AGCAACCACT CGTGAATGGA GTACCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FMR1 ( NM_001185075.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001172004.1 Homo sapiens FMRP translational regulator 1 (FMR1), transcript variant ISO6, mRNA.

Price & Availability↑

CloneID	OHu21881
Clone ID Related Accession (Same CDS sequence)	NM_001185075.1
Accession Version	NM_001185075.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1614bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	synaptic functional regulator FMR1 isoform ISO6
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC086957.1, BQ213316.1, CK825936.1, BX498094.1 and L29074.1. Transcript Variant: This variant (ISO6) lacks an alternate segment and uses a different splice site in the 3' coding region which shifts the reading frame, compared to variant ISO1. The resulting protein (isoform ISO6) has a shorter and distinct C-terminus when it is compared to isoform ISO1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGAGC TGGTGGTGGA AGTGCGGGGC TCCAATGGCG CTTTCTACAA GGCATTTGTA 
AAGGATGTTC ATGAAGATTC AATAACAGTT GCATTTGAAA ACAACTGGCA GCCTGATAGG 
CAGATTCCAT TTCATGATGT CAGATTCCCA CCTCCTGTAG GTTATAATAA AGATATAAAT 
GAAAGTGATG AAGTTGAGGT GTATTCCAGA GCAAATGAAA AAGAGCCTTG CTGTTGGTGG 
TTAGCTAAAG TGAGGATGAT AAAGGGTGAG TTTTATGTGA TAGAATATGC AGCATGTGAT 
GCAACTTACA ATGAAATTGT CACAATTGAA CGTCTAAGAT CTGTTAATCC CAACAAACCT 
GCCACAAAAG ATACTTTCCA TAAGATCAAG CTGGATGTGC CAGAAGACTT ACGGCAAATG 
TGTGCCAAAG AGGCGGCACA TAAGGATTTT AAAAAGGCAG TTGGTGCCTT TTCTGTAACT 
TATGATCCAG AAAATTATCA GCTTGTCATT TTGTCCATCA ATGAAGTCAC CTCAAAGCGA 
GCACATATGC TGATTGACAT GCACTTTCGG AGTCTGCGCA CTAAGTTGTC TCTGATAATG 
AGAAATGAAG AAGCTAGTAA GCAGCTGGAG AGTTCAAGGC AGCTTGCCTC GAGATTTCAT 
GAACAGTTTA TCGTAAGAGA AGATCTGATG GGTCTAGCTA TTGGTACTCA TGGTGCTAAT 
ATTCAGCAAG CTAGAAAAGT ACCTGGGGTC ACTGCTATTG ATCTAGATGA AGATACCTGC 
ACATTTCATA TTTATGGAGA GGATCAGGAT GCAGTGAAAA AAGCTAGAAG CTTTCTCGAA 
TTTGCTGAAG ATGTAATACA AGTTCCAAGG AACTTAGTAG GCAAAGTAAT AGGAAAAAAT 
GGAAAGCTGA TTCAGGAGAT TGTGGACAAG TCAGGAGTTG TGAGGGTGAG GATTGAGGCT 
GAAAATGAGA AAAATGTTCC ACAAGAAGAG GAAATTATGC CACCAAATTC CCTTCCTTCC 
AATAATTCAA GGGTTGGACC TAATGCCCCA GAAGAAAAAA AACATTTAGA TATAAAGGAA 
AACAGCACCC ATTTTTCTCA ACCTAACAGT ACAAAAGTCC AGAGGGTGTT AGTGGCTTCA 
TCAGTTGTAG CAGGGGAATC CCAGAAACCT GAACTCAAGG CTTGGCAGGG TATGGTACCA 
TTTGTTTTTG TGGGAACAAA GGACAGCATC GCTAATGCCA CTGTTCTTTT GGATTATCAC 
CTGAACTATT TAAAGCTCCA ACAGAGGAAG AGAGGGAGAG CTTCCTGCGC AGAGGAGACG 
GACGGCGGCG TGGAGGGGGA GGAAGAGGAC AAGGAGGAAG AGGACGTGGA GGAGGCTTCA 
AAGGAAACGA CGATCACTCC CGAACAGATA ATCGTCCACG TAATCCAAGA GAGGCTAAAG 
GAAGAACAAC AGATGGATCC CTTCAGATCA GAGTTGACTG CAATAATGAA AGGAGTGTCC 
ACACTAAAAC ATTACAGAAT ACCTCCAGTG AAGGTAGTCG GCTGCGCACG GGTAAAGATC 
GTAACCAGAA GAAAGAGAAG CCAGACAGCG TGGATGGTCA GCAACCACTC GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001172004.1
CDS	230..1843
Translation	MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKENSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYHLNYLKLQQRKRGRASCAEETDGGVEGEEEDKEEEDVEEASKETTITPEQIIVHVIQERLKEEQQMDPFRSELTAIMKGVSTLKHYRIPPVKVVGCARVKIVTRRKRSQTAWMVSNHS

Target ORF information:

RefSeq Version	NM_001185075.1
Organism	Homo sapiens(human)
Definition	Homo sapiens FMRP translational regulator 1 (FMR1), transcript variant ISO6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001185075.1

ORF Insert Sequence:

ATGGAGGAGC TGGTGGTGGA AGTGCGGGGC TCCAATGGCG CTTTCTACAA GGCATTTGTA 
AAGGATGTTC ATGAAGATTC AATAACAGTT GCATTTGAAA ACAACTGGCA GCCTGATAGG 
CAGATTCCAT TTCATGATGT CAGATTCCCA CCTCCTGTAG GTTATAATAA AGATATAAAT 
GAAAGTGATG AAGTTGAGGT GTATTCCAGA GCAAATGAAA AAGAGCCTTG CTGTTGGTGG 
TTAGCTAAAG TGAGGATGAT AAAGGGTGAG TTTTATGTGA TAGAATATGC AGCATGTGAT 
GCAACTTACA ATGAAATTGT CACAATTGAA CGTCTAAGAT CTGTTAATCC CAACAAACCT 
GCCACAAAAG ATACTTTCCA TAAGATCAAG CTGGATGTGC CAGAAGACTT ACGGCAAATG 
TGTGCCAAAG AGGCGGCACA TAAGGATTTT AAAAAGGCAG TTGGTGCCTT TTCTGTAACT 
TATGATCCAG AAAATTATCA GCTTGTCATT TTGTCCATCA ATGAAGTCAC CTCAAAGCGA 
GCACATATGC TGATTGACAT GCACTTTCGG AGTCTGCGCA CTAAGTTGTC TCTGATAATG 
AGAAATGAAG AAGCTAGTAA GCAGCTGGAG AGTTCAAGGC AGCTTGCCTC GAGATTTCAT 
GAACAGTTTA TCGTAAGAGA AGATCTGATG GGTCTAGCTA TTGGTACTCA TGGTGCTAAT 
ATTCAGCAAG CTAGAAAAGT ACCTGGGGTC ACTGCTATTG ATCTAGATGA AGATACCTGC 
ACATTTCATA TTTATGGAGA GGATCAGGAT GCAGTGAAAA AAGCTAGAAG CTTTCTCGAA 
TTTGCTGAAG ATGTAATACA AGTTCCAAGG AACTTAGTAG GCAAAGTAAT AGGAAAAAAT 
GGAAAGCTGA TTCAGGAGAT TGTGGACAAG TCAGGAGTTG TGAGGGTGAG GATTGAGGCT 
GAAAATGAGA AAAATGTTCC ACAAGAAGAG GAAATTATGC CACCAAATTC CCTTCCTTCC 
AATAATTCAA GGGTTGGACC TAATGCCCCA GAAGAAAAAA AACATTTAGA TATAAAGGAA 
AACAGCACCC ATTTTTCTCA ACCTAACAGT ACAAAAGTCC AGAGGGTGTT AGTGGCTTCA 
TCAGTTGTAG CAGGGGAATC CCAGAAACCT GAACTCAAGG CTTGGCAGGG TATGGTACCA 
TTTGTTTTTG TGGGAACAAA GGACAGCATC GCTAATGCCA CTGTTCTTTT GGATTATCAC 
CTGAACTATT TAAAGCTCCA ACAGAGGAAG AGAGGGAGAG CTTCCTGCGC AGAGGAGACG 
GACGGCGGCG TGGAGGGGGA GGAAGAGGAC AAGGAGGAAG AGGACGTGGA GGAGGCTTCA 
AAGGAAACGA CGATCACTCC CGAACAGATA ATCGTCCACG TAATCCAAGA GAGGCTAAAG 
GAAGAACAAC AGATGGATCC CTTCAGATCA GAGTTGACTG CAATAATGAA AGGAGTGTCC 
ACACTAAAAC ATTACAGAAT ACCTCCAGTG AAGGTAGTCG GCTGCGCACG GGTAAAGATC 
GTAACCAGAA GAAAGAGAAG CCAGACAGCG TGGATGGTCA GCAACCACTC GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FMR1 ( NM_001185082.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001172011.1 Homo sapiens FMRP translational regulator 1 (FMR1), transcript variant ISO9, mRNA.

Price & Availability↑

CloneID	OHu20575
Clone ID Related Accession (Same CDS sequence)	NM_001185082.2 , NM_001185082.1
Accession Version	NM_001185082.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1761bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	synaptic functional regulator FMR1 isoform ISO9
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from L29074.1 and BC086957.1. On Jun 2, 2019 this sequence version replaced NM_001185082.1. Transcript Variant: This variant (ISO9) lacks an alternate segment and uses a different splice site in the 3' coding region, compared to variant ISO1. The resulting protein (isoform ISO9) is shorter when it is compared to isoform ISO1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.214766.1 [ECO:0000332] ##Evidence-Data-END##

ATGGAGGAGC TGGTGGTGGA AGTGCGGGGC TCCAATGGCG CTTTCTACAA GGCATTTGTA 
AAGGATGTTC ATGAAGATTC AATAACAGTT GCATTTGAAA ACAACTGGCA GCCTGATAGG 
CAGATTCCAT TTCATGATGT CAGATTCCCA CCTCCTGTAG GTTATAATAA AGATATAAAT 
GAAAGTGATG AAGTTGAGGT GTATTCCAGA GCAAATGAAA AAGAGCCTTG CTGTTGGTGG 
TTAGCTAAAG TGAGGATGAT AAAGGGTGAG TTTTATGTGA TAGAATATGC AGCATGTGAT 
GCAACTTACA ATGAAATTGT CACAATTGAA CGTCTAAGAT CTGTTAATCC CAACAAACCT 
GCCACAAAAG ATACTTTCCA TAAGATCAAG CTGGATGTGC CAGAAGACTT ACGGCAAATG 
TGTGCCAAAG AGGCGGCACA TAAGGATTTT AAAAAGGCAG TTGGTGCCTT TTCTGTAACT 
TATGATCCAG AAAATTATCA GCTTGTCATT TTGTCCATCA ATGAAGTCAC CTCAAAGCGA 
GCACATATGC TGATTGACAT GCACTTTCGG AGTCTGCGCA CTAAGTTGTC TCTGATAATG 
AGAAATGAAG AAGCTAGTAA GCAGCTGGAG AGTTCAAGGC AGCTTGCCTC GAGATTTCAT 
GAACAGTTTA TCGTAAGAGA AGATCTGATG GGTCTAGCTA TTGGTACTCA TGGTGCTAAT 
ATTCAGCAAG CTAGAAAAGT ACCTGGGGTC ACTGCTATTG ATCTAGATGA AGATACCTGC 
ACATTTCATA TTTATGGAGA GGATCAGGAT GCAGTGAAAA AAGCTAGAAG CTTTCTCGAA 
TTTGCTGAAG ATGTAATACA AGTTCCAAGG AACTTAGTAG GCAAAGTAAT AGGAAAAAAT 
GGAAAGCTGA TTCAGGAGAT TGTGGACAAG TCAGGAGTTG TGAGGGTGAG GATTGAGGCT 
GAAAATGAGA AAAATGTTCC ACAAGAAGAG GAAATTATGC CACCAAATTC CCTTCCTTCC 
AATAATTCAA GGGTTGGACC TAATGCCCCA GAAGAAAAAA AACATTTAGA TATAAAGGAA 
AACAGCACCC ATTTTTCTCA ACCTAACAGT ACAAAAGTCC AGAGGGGTAT GGTACCATTT 
GTTTTTGTGG GAACAAAGGA CAGCATCGCT AATGCCACTG TTCTTTTGGA TTATCACCTG 
AACTATTTAA AGGAAGTAGA CCAGTTGCGT TTGGAGAGAT TACAAATTGA TGAGCAGTTG 
CGACAGATTG GAGCTAGTTC TAGACCACCA CCAAATCGTA CAGATAAGGA AAAAAGCTAT 
GTGACTGATG ATGGTCAAGG AATGGGTCGA GGTAGTAGAC CTTACAGAAA TAGGGGGCAC 
GGCAGACGCG GTCCTGGATA TACTTCAGCT CCAACAGAGG AAGAGAGGGA GAGCTTCCTG 
CGCAGAGGAG ACGGACGGCG GCGTGGAGGG GGAGGAAGAG GACAAGGAGG AAGAGGACGT 
GGAGGAGGCT TCAAAGGAAA CGACGATCAC TCCCGAACAG ATAATCGTCC ACGTAATCCA 
AGAGAGGCTA AAGGAAGAAC AACAGATGGA TCCCTTCAGA TCAGAGTTGA CTGCAATAAT 
GAAAGGAGTG TCCACACTAA AACATTACAG AATACCTCCA GTGAAGGTAG TCGGCTGCGC 
ACGGGTAAAG ATCGTAACCA GAAGAAAGAG AAGCCAGACA GCGTGGATGG TCAGCAACCA 
CTCGTGAATG GAGTACCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001172011.1
CDS	262..2022
Translation	MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKENSTHFSQPNSTKVQRGMVPFVFVGTKDSIANATVLLDYHLNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRGHGRRGPGYTSAPTEEERESFLRRGDGRRRGGGGRGQGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSSEGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP

Target ORF information:

RefSeq Version	NM_001185082.2
Organism	Homo sapiens(human)
Definition	Homo sapiens FMRP translational regulator 1 (FMR1), transcript variant ISO9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001185082.2

ORF Insert Sequence:

ATGGAGGAGC TGGTGGTGGA AGTGCGGGGC TCCAATGGCG CTTTCTACAA GGCATTTGTA 
AAGGATGTTC ATGAAGATTC AATAACAGTT GCATTTGAAA ACAACTGGCA GCCTGATAGG 
CAGATTCCAT TTCATGATGT CAGATTCCCA CCTCCTGTAG GTTATAATAA AGATATAAAT 
GAAAGTGATG AAGTTGAGGT GTATTCCAGA GCAAATGAAA AAGAGCCTTG CTGTTGGTGG 
TTAGCTAAAG TGAGGATGAT AAAGGGTGAG TTTTATGTGA TAGAATATGC AGCATGTGAT 
GCAACTTACA ATGAAATTGT CACAATTGAA CGTCTAAGAT CTGTTAATCC CAACAAACCT 
GCCACAAAAG ATACTTTCCA TAAGATCAAG CTGGATGTGC CAGAAGACTT ACGGCAAATG 
TGTGCCAAAG AGGCGGCACA TAAGGATTTT AAAAAGGCAG TTGGTGCCTT TTCTGTAACT 
TATGATCCAG AAAATTATCA GCTTGTCATT TTGTCCATCA ATGAAGTCAC CTCAAAGCGA 
GCACATATGC TGATTGACAT GCACTTTCGG AGTCTGCGCA CTAAGTTGTC TCTGATAATG 
AGAAATGAAG AAGCTAGTAA GCAGCTGGAG AGTTCAAGGC AGCTTGCCTC GAGATTTCAT 
GAACAGTTTA TCGTAAGAGA AGATCTGATG GGTCTAGCTA TTGGTACTCA TGGTGCTAAT 
ATTCAGCAAG CTAGAAAAGT ACCTGGGGTC ACTGCTATTG ATCTAGATGA AGATACCTGC 
ACATTTCATA TTTATGGAGA GGATCAGGAT GCAGTGAAAA AAGCTAGAAG CTTTCTCGAA 
TTTGCTGAAG ATGTAATACA AGTTCCAAGG AACTTAGTAG GCAAAGTAAT AGGAAAAAAT 
GGAAAGCTGA TTCAGGAGAT TGTGGACAAG TCAGGAGTTG TGAGGGTGAG GATTGAGGCT 
GAAAATGAGA AAAATGTTCC ACAAGAAGAG GAAATTATGC CACCAAATTC CCTTCCTTCC 
AATAATTCAA GGGTTGGACC TAATGCCCCA GAAGAAAAAA AACATTTAGA TATAAAGGAA 
AACAGCACCC ATTTTTCTCA ACCTAACAGT ACAAAAGTCC AGAGGGGTAT GGTACCATTT 
GTTTTTGTGG GAACAAAGGA CAGCATCGCT AATGCCACTG TTCTTTTGGA TTATCACCTG 
AACTATTTAA AGGAAGTAGA CCAGTTGCGT TTGGAGAGAT TACAAATTGA TGAGCAGTTG 
CGACAGATTG GAGCTAGTTC TAGACCACCA CCAAATCGTA CAGATAAGGA AAAAAGCTAT 
GTGACTGATG ATGGTCAAGG AATGGGTCGA GGTAGTAGAC CTTACAGAAA TAGGGGGCAC 
GGCAGACGCG GTCCTGGATA TACTTCAGCT CCAACAGAGG AAGAGAGGGA GAGCTTCCTG 
CGCAGAGGAG ACGGACGGCG GCGTGGAGGG GGAGGAAGAG GACAAGGAGG AAGAGGACGT 
GGAGGAGGCT TCAAAGGAAA CGACGATCAC TCCCGAACAG ATAATCGTCC ACGTAATCCA 
AGAGAGGCTA AAGGAAGAAC AACAGATGGA TCCCTTCAGA TCAGAGTTGA CTGCAATAAT 
GAAAGGAGTG TCCACACTAA AACATTACAG AATACCTCCA GTGAAGGTAG TCGGCTGCGC 
ACGGGTAAAG ATCGTAACCA GAAGAAAGAG AAGCCAGACA GCGTGGATGG TCAGCAACCA 
CTCGTGAATG GAGTACCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FMR1 ( NM_001185082.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001172011.1 Homo sapiens fragile X mental retardation 1 (FMR1), transcript variant ISO9, mRNA.

Price & Availability↑

CloneID	OHu20575
Clone ID Related Accession (Same CDS sequence)	NM_001185082.2 , NM_001185082.1
Accession Version	NM_001185082.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1761bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-03
Organism	Homo sapiens(human)
Product	synaptic functional regulator FMR1 isoform ISO9
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC086957.1 and L29074.1. Transcript Variant: This variant (ISO9) lacks an alternate segment and uses a different splice site in the 3' coding region, compared to variant ISO1. The resulting protein (isoform ISO9) is shorter when it is compared to isoform ISO1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.214766.1, SRR1803617.120248.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGAGC TGGTGGTGGA AGTGCGGGGC TCCAATGGCG CTTTCTACAA GGCATTTGTA 
AAGGATGTTC ATGAAGATTC AATAACAGTT GCATTTGAAA ACAACTGGCA GCCTGATAGG 
CAGATTCCAT TTCATGATGT CAGATTCCCA CCTCCTGTAG GTTATAATAA AGATATAAAT 
GAAAGTGATG AAGTTGAGGT GTATTCCAGA GCAAATGAAA AAGAGCCTTG CTGTTGGTGG 
TTAGCTAAAG TGAGGATGAT AAAGGGTGAG TTTTATGTGA TAGAATATGC AGCATGTGAT 
GCAACTTACA ATGAAATTGT CACAATTGAA CGTCTAAGAT CTGTTAATCC CAACAAACCT 
GCCACAAAAG ATACTTTCCA TAAGATCAAG CTGGATGTGC CAGAAGACTT ACGGCAAATG 
TGTGCCAAAG AGGCGGCACA TAAGGATTTT AAAAAGGCAG TTGGTGCCTT TTCTGTAACT 
TATGATCCAG AAAATTATCA GCTTGTCATT TTGTCCATCA ATGAAGTCAC CTCAAAGCGA 
GCACATATGC TGATTGACAT GCACTTTCGG AGTCTGCGCA CTAAGTTGTC TCTGATAATG 
AGAAATGAAG AAGCTAGTAA GCAGCTGGAG AGTTCAAGGC AGCTTGCCTC GAGATTTCAT 
GAACAGTTTA TCGTAAGAGA AGATCTGATG GGTCTAGCTA TTGGTACTCA TGGTGCTAAT 
ATTCAGCAAG CTAGAAAAGT ACCTGGGGTC ACTGCTATTG ATCTAGATGA AGATACCTGC 
ACATTTCATA TTTATGGAGA GGATCAGGAT GCAGTGAAAA AAGCTAGAAG CTTTCTCGAA 
TTTGCTGAAG ATGTAATACA AGTTCCAAGG AACTTAGTAG GCAAAGTAAT AGGAAAAAAT 
GGAAAGCTGA TTCAGGAGAT TGTGGACAAG TCAGGAGTTG TGAGGGTGAG GATTGAGGCT 
GAAAATGAGA AAAATGTTCC ACAAGAAGAG GAAATTATGC CACCAAATTC CCTTCCTTCC 
AATAATTCAA GGGTTGGACC TAATGCCCCA GAAGAAAAAA AACATTTAGA TATAAAGGAA 
AACAGCACCC ATTTTTCTCA ACCTAACAGT ACAAAAGTCC AGAGGGGTAT GGTACCATTT 
GTTTTTGTGG GAACAAAGGA CAGCATCGCT AATGCCACTG TTCTTTTGGA TTATCACCTG 
AACTATTTAA AGGAAGTAGA CCAGTTGCGT TTGGAGAGAT TACAAATTGA TGAGCAGTTG 
CGACAGATTG GAGCTAGTTC TAGACCACCA CCAAATCGTA CAGATAAGGA AAAAAGCTAT 
GTGACTGATG ATGGTCAAGG AATGGGTCGA GGTAGTAGAC CTTACAGAAA TAGGGGGCAC 
GGCAGACGCG GTCCTGGATA TACTTCAGCT CCAACAGAGG AAGAGAGGGA GAGCTTCCTG 
CGCAGAGGAG ACGGACGGCG GCGTGGAGGG GGAGGAAGAG GACAAGGAGG AAGAGGACGT 
GGAGGAGGCT TCAAAGGAAA CGACGATCAC TCCCGAACAG ATAATCGTCC ACGTAATCCA 
AGAGAGGCTA AAGGAAGAAC AACAGATGGA TCCCTTCAGA TCAGAGTTGA CTGCAATAAT 
GAAAGGAGTG TCCACACTAA AACATTACAG AATACCTCCA GTGAAGGTAG TCGGCTGCGC 
ACGGGTAAAG ATCGTAACCA GAAGAAAGAG AAGCCAGACA GCGTGGATGG TCAGCAACCA 
CTCGTGAATG GAGTACCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001172011.1
CDS	230..1990
Translation	MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKENSTHFSQPNSTKVQRGMVPFVFVGTKDSIANATVLLDYHLNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRGHGRRGPGYTSAPTEEERESFLRRGDGRRRGGGGRGQGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSSEGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP

Target ORF information:

RefSeq Version	NM_001185082.1
Organism	Homo sapiens(human)
Definition	Homo sapiens fragile X mental retardation 1 (FMR1), transcript variant ISO9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001185082.1

ORF Insert Sequence:

ATGGAGGAGC TGGTGGTGGA AGTGCGGGGC TCCAATGGCG CTTTCTACAA GGCATTTGTA 
AAGGATGTTC ATGAAGATTC AATAACAGTT GCATTTGAAA ACAACTGGCA GCCTGATAGG 
CAGATTCCAT TTCATGATGT CAGATTCCCA CCTCCTGTAG GTTATAATAA AGATATAAAT 
GAAAGTGATG AAGTTGAGGT GTATTCCAGA GCAAATGAAA AAGAGCCTTG CTGTTGGTGG 
TTAGCTAAAG TGAGGATGAT AAAGGGTGAG TTTTATGTGA TAGAATATGC AGCATGTGAT 
GCAACTTACA ATGAAATTGT CACAATTGAA CGTCTAAGAT CTGTTAATCC CAACAAACCT 
GCCACAAAAG ATACTTTCCA TAAGATCAAG CTGGATGTGC CAGAAGACTT ACGGCAAATG 
TGTGCCAAAG AGGCGGCACA TAAGGATTTT AAAAAGGCAG TTGGTGCCTT TTCTGTAACT 
TATGATCCAG AAAATTATCA GCTTGTCATT TTGTCCATCA ATGAAGTCAC CTCAAAGCGA 
GCACATATGC TGATTGACAT GCACTTTCGG AGTCTGCGCA CTAAGTTGTC TCTGATAATG 
AGAAATGAAG AAGCTAGTAA GCAGCTGGAG AGTTCAAGGC AGCTTGCCTC GAGATTTCAT 
GAACAGTTTA TCGTAAGAGA AGATCTGATG GGTCTAGCTA TTGGTACTCA TGGTGCTAAT 
ATTCAGCAAG CTAGAAAAGT ACCTGGGGTC ACTGCTATTG ATCTAGATGA AGATACCTGC 
ACATTTCATA TTTATGGAGA GGATCAGGAT GCAGTGAAAA AAGCTAGAAG CTTTCTCGAA 
TTTGCTGAAG ATGTAATACA AGTTCCAAGG AACTTAGTAG GCAAAGTAAT AGGAAAAAAT 
GGAAAGCTGA TTCAGGAGAT TGTGGACAAG TCAGGAGTTG TGAGGGTGAG GATTGAGGCT 
GAAAATGAGA AAAATGTTCC ACAAGAAGAG GAAATTATGC CACCAAATTC CCTTCCTTCC 
AATAATTCAA GGGTTGGACC TAATGCCCCA GAAGAAAAAA AACATTTAGA TATAAAGGAA 
AACAGCACCC ATTTTTCTCA ACCTAACAGT ACAAAAGTCC AGAGGGGTAT GGTACCATTT 
GTTTTTGTGG GAACAAAGGA CAGCATCGCT AATGCCACTG TTCTTTTGGA TTATCACCTG 
AACTATTTAA AGGAAGTAGA CCAGTTGCGT TTGGAGAGAT TACAAATTGA TGAGCAGTTG 
CGACAGATTG GAGCTAGTTC TAGACCACCA CCAAATCGTA CAGATAAGGA AAAAAGCTAT 
GTGACTGATG ATGGTCAAGG AATGGGTCGA GGTAGTAGAC CTTACAGAAA TAGGGGGCAC 
GGCAGACGCG GTCCTGGATA TACTTCAGCT CCAACAGAGG AAGAGAGGGA GAGCTTCCTG 
CGCAGAGGAG ACGGACGGCG GCGTGGAGGG GGAGGAAGAG GACAAGGAGG AAGAGGACGT 
GGAGGAGGCT TCAAAGGAAA CGACGATCAC TCCCGAACAG ATAATCGTCC ACGTAATCCA 
AGAGAGGCTA AAGGAAGAAC AACAGATGGA TCCCTTCAGA TCAGAGTTGA CTGCAATAAT 
GAAAGGAGTG TCCACACTAA AACATTACAG AATACCTCCA GTGAAGGTAG TCGGCTGCGC 
ACGGGTAAAG ATCGTAACCA GAAGAAAGAG AAGCCAGACA GCGTGGATGG TCAGCAACCA 
CTCGTGAATG GAGTACCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FMR1 ( NM_001185076.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001172005.1 Homo sapiens FMRP translational regulator 1 (FMR1), transcript variant ISO7, mRNA.

Price & Availability↑

CloneID	OHu21356
Clone ID Related Accession (Same CDS sequence)	NM_001185076.1
Accession Version	NM_001185076.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1836bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	synaptic functional regulator FMR1 isoform ISO7
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC086957.1, BQ213316.1, BQ417290.1, CN315330.1, CX871385.1 and L29074.1. Transcript Variant: This variant (ISO7) lacks an alternate segment, compared to variant ISO1. The resulting protein (isoform ISO7) is shorter when it is compared to isoform ISO1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.39913.1, SRR1803616.10727.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGAGC TGGTGGTGGA AGTGCGGGGC TCCAATGGCG CTTTCTACAA GGCATTTGTA 
AAGGATGTTC ATGAAGATTC AATAACAGTT GCATTTGAAA ACAACTGGCA GCCTGATAGG 
CAGATTCCAT TTCATGATGT CAGATTCCCA CCTCCTGTAG GTTATAATAA AGATATAAAT 
GAAAGTGATG AAGTTGAGGT GTATTCCAGA GCAAATGAAA AAGAGCCTTG CTGTTGGTGG 
TTAGCTAAAG TGAGGATGAT AAAGGGTGAG TTTTATGTGA TAGAATATGC AGCATGTGAT 
GCAACTTACA ATGAAATTGT CACAATTGAA CGTCTAAGAT CTGTTAATCC CAACAAACCT 
GCCACAAAAG ATACTTTCCA TAAGATCAAG CTGGATGTGC CAGAAGACTT ACGGCAAATG 
TGTGCCAAAG AGGCGGCACA TAAGGATTTT AAAAAGGCAG TTGGTGCCTT TTCTGTAACT 
TATGATCCAG AAAATTATCA GCTTGTCATT TTGTCCATCA ATGAAGTCAC CTCAAAGCGA 
GCACATATGC TGATTGACAT GCACTTTCGG AGTCTGCGCA CTAAGTTGTC TCTGATAATG 
AGAAATGAAG AAGCTAGTAA GCAGCTGGAG AGTTCAAGGC AGCTTGCCTC GAGATTTCAT 
GAACAGTTTA TCGTAAGAGA AGATCTGATG GGTCTAGCTA TTGGTACTCA TGGTGCTAAT 
ATTCAGCAAG CTAGAAAAGT ACCTGGGGTC ACTGCTATTG ATCTAGATGA AGATACCTGC 
ACATTTCATA TTTATGGAGA GGATCAGGAT GCAGTGAAAA AAGCTAGAAG CTTTCTCGAA 
TTTGCTGAAG ATGTAATACA AGTTCCAAGG AACTTAGTAG GCAAAGTAAT AGGAAAAAAT 
GGAAAGCTGA TTCAGGAGAT TGTGGACAAG TCAGGAGTTG TGAGGGTGAG GATTGAGGCT 
GAAAATGAGA AAAATGTTCC ACAAGAAGAG GAAATTATGC CACCAAATTC CCTTCCTTCC 
AATAATTCAA GGGTTGGACC TAATGCCCCA GAAGAAAAAA AACATTTAGA TATAAAGGAA 
AACAGCACCC ATTTTTCTCA ACCTAACAGT ACAAAAGTCC AGAGGGGTAT GGTACCATTT 
GTTTTTGTGG GAACAAAGGA CAGCATCGCT AATGCCACTG TTCTTTTGGA TTATCACCTG 
AACTATTTAA AGGAAGTAGA CCAGTTGCGT TTGGAGAGAT TACAAATTGA TGAGCAGTTG 
CGACAGATTG GAGCTAGTTC TAGACCACCA CCAAATCGTA CAGATAAGGA AAAAAGCTAT 
GTGACTGATG ATGGTCAAGG AATGGGTCGA GGTAGTAGAC CTTACAGAAA TAGGGGGCAC 
GGCAGACGCG GTCCTGGATA TACTTCAGGA ACTAATTCTG AAGCATCAAA TGCTTCTGAA 
ACAGAATCTG ACCACAGAGA CGAACTCAGT GATTGGTCAT TAGCTCCAAC AGAGGAAGAG 
AGGGAGAGCT TCCTGCGCAG AGGAGACGGA CGGCGGCGTG GAGGGGGAGG AAGAGGACAA 
GGAGGAAGAG GACGTGGAGG AGGCTTCAAA GGAAACGACG ATCACTCCCG AACAGATAAT 
CGTCCACGTA ATCCAAGAGA GGCTAAAGGA AGAACAACAG ATGGATCCCT TCAGATCAGA 
GTTGACTGCA ATAATGAAAG GAGTGTCCAC ACTAAAACAT TACAGAATAC CTCCAGTGAA 
GGTAGTCGGC TGCGCACGGG TAAAGATCGT AACCAGAAGA AAGAGAAGCC AGACAGCGTG 
GATGGTCAGC AACCACTCGT GAATGGAGTA CCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001172005.1
CDS	230..2065
Translation	MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKENSTHFSQPNSTKVQRGMVPFVFVGTKDSIANATVLLDYHLNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRGHGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRGQGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSSEGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP

Target ORF information:

RefSeq Version	NM_001185076.1
Organism	Homo sapiens(human)
Definition	Homo sapiens FMRP translational regulator 1 (FMR1), transcript variant ISO7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001185076.1

ORF Insert Sequence:

ATGGAGGAGC TGGTGGTGGA AGTGCGGGGC TCCAATGGCG CTTTCTACAA GGCATTTGTA 
AAGGATGTTC ATGAAGATTC AATAACAGTT GCATTTGAAA ACAACTGGCA GCCTGATAGG 
CAGATTCCAT TTCATGATGT CAGATTCCCA CCTCCTGTAG GTTATAATAA AGATATAAAT 
GAAAGTGATG AAGTTGAGGT GTATTCCAGA GCAAATGAAA AAGAGCCTTG CTGTTGGTGG 
TTAGCTAAAG TGAGGATGAT AAAGGGTGAG TTTTATGTGA TAGAATATGC AGCATGTGAT 
GCAACTTACA ATGAAATTGT CACAATTGAA CGTCTAAGAT CTGTTAATCC CAACAAACCT 
GCCACAAAAG ATACTTTCCA TAAGATCAAG CTGGATGTGC CAGAAGACTT ACGGCAAATG 
TGTGCCAAAG AGGCGGCACA TAAGGATTTT AAAAAGGCAG TTGGTGCCTT TTCTGTAACT 
TATGATCCAG AAAATTATCA GCTTGTCATT TTGTCCATCA ATGAAGTCAC CTCAAAGCGA 
GCACATATGC TGATTGACAT GCACTTTCGG AGTCTGCGCA CTAAGTTGTC TCTGATAATG 
AGAAATGAAG AAGCTAGTAA GCAGCTGGAG AGTTCAAGGC AGCTTGCCTC GAGATTTCAT 
GAACAGTTTA TCGTAAGAGA AGATCTGATG GGTCTAGCTA TTGGTACTCA TGGTGCTAAT 
ATTCAGCAAG CTAGAAAAGT ACCTGGGGTC ACTGCTATTG ATCTAGATGA AGATACCTGC 
ACATTTCATA TTTATGGAGA GGATCAGGAT GCAGTGAAAA AAGCTAGAAG CTTTCTCGAA 
TTTGCTGAAG ATGTAATACA AGTTCCAAGG AACTTAGTAG GCAAAGTAAT AGGAAAAAAT 
GGAAAGCTGA TTCAGGAGAT TGTGGACAAG TCAGGAGTTG TGAGGGTGAG GATTGAGGCT 
GAAAATGAGA AAAATGTTCC ACAAGAAGAG GAAATTATGC CACCAAATTC CCTTCCTTCC 
AATAATTCAA GGGTTGGACC TAATGCCCCA GAAGAAAAAA AACATTTAGA TATAAAGGAA 
AACAGCACCC ATTTTTCTCA ACCTAACAGT ACAAAAGTCC AGAGGGGTAT GGTACCATTT 
GTTTTTGTGG GAACAAAGGA CAGCATCGCT AATGCCACTG TTCTTTTGGA TTATCACCTG 
AACTATTTAA AGGAAGTAGA CCAGTTGCGT TTGGAGAGAT TACAAATTGA TGAGCAGTTG 
CGACAGATTG GAGCTAGTTC TAGACCACCA CCAAATCGTA CAGATAAGGA AAAAAGCTAT 
GTGACTGATG ATGGTCAAGG AATGGGTCGA GGTAGTAGAC CTTACAGAAA TAGGGGGCAC 
GGCAGACGCG GTCCTGGATA TACTTCAGGA ACTAATTCTG AAGCATCAAA TGCTTCTGAA 
ACAGAATCTG ACCACAGAGA CGAACTCAGT GATTGGTCAT TAGCTCCAAC AGAGGAAGAG 
AGGGAGAGCT TCCTGCGCAG AGGAGACGGA CGGCGGCGTG GAGGGGGAGG AAGAGGACAA 
GGAGGAAGAG GACGTGGAGG AGGCTTCAAA GGAAACGACG ATCACTCCCG AACAGATAAT 
CGTCCACGTA ATCCAAGAGA GGCTAAAGGA AGAACAACAG ATGGATCCCT TCAGATCAGA 
GTTGACTGCA ATAATGAAAG GAGTGTCCAC ACTAAAACAT TACAGAATAC CTCCAGTGAA 
GGTAGTCGGC TGCGCACGGG TAAAGATCGT AACCAGAAGA AAGAGAAGCC AGACAGCGTG 
GATGGTCAGC AACCACTCGT GAATGGAGTA CCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FMR1 ( NM_001185081.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001172010.1 Homo sapiens fragile X mental retardation 1 (FMR1), transcript variant ISO12, mRNA.

Price & Availability↑

CloneID	OHu21769
Clone ID Related Accession (Same CDS sequence)	NM_001185081.1 , NM_001185081.2
Accession Version	NM_001185081.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1551bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-03
Organism	Homo sapiens(human)
Product	synaptic functional regulator FMR1 isoform ISO12
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC086957.1, BQ213316.1, CK825936.1, BQ287827.1 and L29074.1. Transcript Variant: This variant (ISO12) lacks two alternate segments and uses a different splice site which changes the reading frame, compared to variant ISO1. The resulting protein (isoform ISO12) has a shorter and distinct C-terminus when it is compared to isoform ISO1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGAGC TGGTGGTGGA AGTGCGGGGC TCCAATGGCG CTTTCTACAA GGCATTTGTA 
AAGGATGTTC ATGAAGATTC AATAACAGTT GCATTTGAAA ACAACTGGCA GCCTGATAGG 
CAGATTCCAT TTCATGATGT CAGATTCCCA CCTCCTGTAG GTTATAATAA AGATATAAAT 
GAAAGTGATG AAGTTGAGGT GTATTCCAGA GCAAATGAAA AAGAGCCTTG CTGTTGGTGG 
TTAGCTAAAG TGAGGATGAT AAAGGGTGAG TTTTATGTGA TAGAATATGC AGCATGTGAT 
GCAACTTACA ATGAAATTGT CACAATTGAA CGTCTAAGAT CTGTTAATCC CAACAAACCT 
GCCACAAAAG ATACTTTCCA TAAGATCAAG CTGGATGTGC CAGAAGACTT ACGGCAAATG 
TGTGCCAAAG AGGCGGCACA TAAGGATTTT AAAAAGGCAG TTGGTGCCTT TTCTGTAACT 
TATGATCCAG AAAATTATCA GCTTGTCATT TTGTCCATCA ATGAAGTCAC CTCAAAGCGA 
GCACATATGC TGATTGACAT GCACTTTCGG AGTCTGCGCA CTAAGTTGTC TCTGATAATG 
AGAAATGAAG AAGCTAGTAA GCAGCTGGAG AGTTCAAGGC AGCTTGCCTC GAGATTTCAT 
GAACAGTTTA TCGTAAGAGA AGATCTGATG GGTCTAGCTA TTGGTACTCA TGGTGCTAAT 
ATTCAGCAAG CTAGAAAAGT ACCTGGGGTC ACTGCTATTG ATCTAGATGA AGATACCTGC 
ACATTTCATA TTTATGGAGA GGATCAGGAT GCAGTGAAAA AAGCTAGAAG CTTTCTCGAA 
TTTGCTGAAG ATGTAATACA AGTTCCAAGG AACTTAGTAG GCAAAGTAAT AGGAAAAAAT 
GGAAAGCTGA TTCAGGAGAT TGTGGACAAG TCAGGAGTTG TGAGGGTGAG GATTGAGGCT 
GAAAATGAGA AAAATGTTCC ACAAGAAGAG GAAATTATGC CACCAAATTC CCTTCCTTCC 
AATAATTCAA GGGTTGGACC TAATGCCCCA GAAGAAAAAA AACATTTAGA TATAAAGGAA 
AACAGCACCC ATTTTTCTCA ACCTAACAGT ACAAAAGTCC AGAGGGGTAT GGTACCATTT 
GTTTTTGTGG GAACAAAGGA CAGCATCGCT AATGCCACTG TTCTTTTGGA TTATCACCTG 
AACTATTTAA AGCTCCAACA GAGGAAGAGA GGGAGAGCTT CCTGCGCAGA GGAGACGGAC 
GGCGGCGTGG AGGGGGAGGA AGAGGACAAG GAGGAAGAGG ACGTGGAGGA GGCTTCAAAG 
GAAACGACGA TCACTCCCGA ACAGATAATC GTCCACGTAA TCCAAGAGAG GCTAAAGGAA 
GAACAACAGA TGGATCCCTT CAGATCAGAG TTGACTGCAA TAATGAAAGG AGTGTCCACA 
CTAAAACATT ACAGAATACC TCCAGTGAAG GTAGTCGGCT GCGCACGGGT AAAGATCGTA 
ACCAGAAGAA AGAGAAGCCA GACAGCGTGG ATGGTCAGCA ACCACTCGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001172010.1
CDS	230..1780
Translation	MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKENSTHFSQPNSTKVQRGMVPFVFVGTKDSIANATVLLDYHLNYLKLQQRKRGRASCAEETDGGVEGEEEDKEEEDVEEASKETTITPEQIIVHVIQERLKEEQQMDPFRSELTAIMKGVSTLKHYRIPPVKVVGCARVKIVTRRKRSQTAWMVSNHS

Target ORF information:

RefSeq Version	NM_001185081.1
Organism	Homo sapiens(human)
Definition	Homo sapiens fragile X mental retardation 1 (FMR1), transcript variant ISO12, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001185081.1

ORF Insert Sequence:

ATGGAGGAGC TGGTGGTGGA AGTGCGGGGC TCCAATGGCG CTTTCTACAA GGCATTTGTA 
AAGGATGTTC ATGAAGATTC AATAACAGTT GCATTTGAAA ACAACTGGCA GCCTGATAGG 
CAGATTCCAT TTCATGATGT CAGATTCCCA CCTCCTGTAG GTTATAATAA AGATATAAAT 
GAAAGTGATG AAGTTGAGGT GTATTCCAGA GCAAATGAAA AAGAGCCTTG CTGTTGGTGG 
TTAGCTAAAG TGAGGATGAT AAAGGGTGAG TTTTATGTGA TAGAATATGC AGCATGTGAT 
GCAACTTACA ATGAAATTGT CACAATTGAA CGTCTAAGAT CTGTTAATCC CAACAAACCT 
GCCACAAAAG ATACTTTCCA TAAGATCAAG CTGGATGTGC CAGAAGACTT ACGGCAAATG 
TGTGCCAAAG AGGCGGCACA TAAGGATTTT AAAAAGGCAG TTGGTGCCTT TTCTGTAACT 
TATGATCCAG AAAATTATCA GCTTGTCATT TTGTCCATCA ATGAAGTCAC CTCAAAGCGA 
GCACATATGC TGATTGACAT GCACTTTCGG AGTCTGCGCA CTAAGTTGTC TCTGATAATG 
AGAAATGAAG AAGCTAGTAA GCAGCTGGAG AGTTCAAGGC AGCTTGCCTC GAGATTTCAT 
GAACAGTTTA TCGTAAGAGA AGATCTGATG GGTCTAGCTA TTGGTACTCA TGGTGCTAAT 
ATTCAGCAAG CTAGAAAAGT ACCTGGGGTC ACTGCTATTG ATCTAGATGA AGATACCTGC 
ACATTTCATA TTTATGGAGA GGATCAGGAT GCAGTGAAAA AAGCTAGAAG CTTTCTCGAA 
TTTGCTGAAG ATGTAATACA AGTTCCAAGG AACTTAGTAG GCAAAGTAAT AGGAAAAAAT 
GGAAAGCTGA TTCAGGAGAT TGTGGACAAG TCAGGAGTTG TGAGGGTGAG GATTGAGGCT 
GAAAATGAGA AAAATGTTCC ACAAGAAGAG GAAATTATGC CACCAAATTC CCTTCCTTCC 
AATAATTCAA GGGTTGGACC TAATGCCCCA GAAGAAAAAA AACATTTAGA TATAAAGGAA 
AACAGCACCC ATTTTTCTCA ACCTAACAGT ACAAAAGTCC AGAGGGGTAT GGTACCATTT 
GTTTTTGTGG GAACAAAGGA CAGCATCGCT AATGCCACTG TTCTTTTGGA TTATCACCTG 
AACTATTTAA AGCTCCAACA GAGGAAGAGA GGGAGAGCTT CCTGCGCAGA GGAGACGGAC 
GGCGGCGTGG AGGGGGAGGA AGAGGACAAG GAGGAAGAGG ACGTGGAGGA GGCTTCAAAG 
GAAACGACGA TCACTCCCGA ACAGATAATC GTCCACGTAA TCCAAGAGAG GCTAAAGGAA 
GAACAACAGA TGGATCCCTT CAGATCAGAG TTGACTGCAA TAATGAAAGG AGTGTCCACA 
CTAAAACATT ACAGAATACC TCCAGTGAAG GTAGTCGGCT GCGCACGGGT AAAGATCGTA 
ACCAGAAGAA AGAGAAGCCA GACAGCGTGG ATGGTCAGCA ACCACTCGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FMR1 ( NM_001185081.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001172010.1 Homo sapiens FMRP translational regulator 1 (FMR1), transcript variant ISO12, mRNA.

Price & Availability↑

CloneID	OHu21769
Clone ID Related Accession (Same CDS sequence)	NM_001185081.1 , NM_001185081.2
Accession Version	NM_001185081.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1551bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	synaptic functional regulator FMR1 isoform ISO12
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from L29074.1, BC086957.1, BQ213316.1, CK825936.1 and BQ287827.1. On Jun 2, 2019 this sequence version replaced NM_001185081.1. Transcript Variant: This variant (ISO12) lacks two alternate segments and uses a different splice site which changes the reading frame, compared to variant ISO1. The resulting protein (isoform ISO12) has a shorter and distinct C-terminus when it is compared to isoform ISO1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGAGC TGGTGGTGGA AGTGCGGGGC TCCAATGGCG CTTTCTACAA GGCATTTGTA 
AAGGATGTTC ATGAAGATTC AATAACAGTT GCATTTGAAA ACAACTGGCA GCCTGATAGG 
CAGATTCCAT TTCATGATGT CAGATTCCCA CCTCCTGTAG GTTATAATAA AGATATAAAT 
GAAAGTGATG AAGTTGAGGT GTATTCCAGA GCAAATGAAA AAGAGCCTTG CTGTTGGTGG 
TTAGCTAAAG TGAGGATGAT AAAGGGTGAG TTTTATGTGA TAGAATATGC AGCATGTGAT 
GCAACTTACA ATGAAATTGT CACAATTGAA CGTCTAAGAT CTGTTAATCC CAACAAACCT 
GCCACAAAAG ATACTTTCCA TAAGATCAAG CTGGATGTGC CAGAAGACTT ACGGCAAATG 
TGTGCCAAAG AGGCGGCACA TAAGGATTTT AAAAAGGCAG TTGGTGCCTT TTCTGTAACT 
TATGATCCAG AAAATTATCA GCTTGTCATT TTGTCCATCA ATGAAGTCAC CTCAAAGCGA 
GCACATATGC TGATTGACAT GCACTTTCGG AGTCTGCGCA CTAAGTTGTC TCTGATAATG 
AGAAATGAAG AAGCTAGTAA GCAGCTGGAG AGTTCAAGGC AGCTTGCCTC GAGATTTCAT 
GAACAGTTTA TCGTAAGAGA AGATCTGATG GGTCTAGCTA TTGGTACTCA TGGTGCTAAT 
ATTCAGCAAG CTAGAAAAGT ACCTGGGGTC ACTGCTATTG ATCTAGATGA AGATACCTGC 
ACATTTCATA TTTATGGAGA GGATCAGGAT GCAGTGAAAA AAGCTAGAAG CTTTCTCGAA 
TTTGCTGAAG ATGTAATACA AGTTCCAAGG AACTTAGTAG GCAAAGTAAT AGGAAAAAAT 
GGAAAGCTGA TTCAGGAGAT TGTGGACAAG TCAGGAGTTG TGAGGGTGAG GATTGAGGCT 
GAAAATGAGA AAAATGTTCC ACAAGAAGAG GAAATTATGC CACCAAATTC CCTTCCTTCC 
AATAATTCAA GGGTTGGACC TAATGCCCCA GAAGAAAAAA AACATTTAGA TATAAAGGAA 
AACAGCACCC ATTTTTCTCA ACCTAACAGT ACAAAAGTCC AGAGGGGTAT GGTACCATTT 
GTTTTTGTGG GAACAAAGGA CAGCATCGCT AATGCCACTG TTCTTTTGGA TTATCACCTG 
AACTATTTAA AGCTCCAACA GAGGAAGAGA GGGAGAGCTT CCTGCGCAGA GGAGACGGAC 
GGCGGCGTGG AGGGGGAGGA AGAGGACAAG GAGGAAGAGG ACGTGGAGGA GGCTTCAAAG 
GAAACGACGA TCACTCCCGA ACAGATAATC GTCCACGTAA TCCAAGAGAG GCTAAAGGAA 
GAACAACAGA TGGATCCCTT CAGATCAGAG TTGACTGCAA TAATGAAAGG AGTGTCCACA 
CTAAAACATT ACAGAATACC TCCAGTGAAG GTAGTCGGCT GCGCACGGGT AAAGATCGTA 
ACCAGAAGAA AGAGAAGCCA GACAGCGTGG ATGGTCAGCA ACCACTCGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001172010.1
CDS	262..1812
Translation	MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKENSTHFSQPNSTKVQRGMVPFVFVGTKDSIANATVLLDYHLNYLKLQQRKRGRASCAEETDGGVEGEEEDKEEEDVEEASKETTITPEQIIVHVIQERLKEEQQMDPFRSELTAIMKGVSTLKHYRIPPVKVVGCARVKIVTRRKRSQTAWMVSNHS

Target ORF information:

RefSeq Version	NM_001185081.2
Organism	Homo sapiens(human)
Definition	Homo sapiens FMRP translational regulator 1 (FMR1), transcript variant ISO12, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001185081.2

ORF Insert Sequence:

ATGGAGGAGC TGGTGGTGGA AGTGCGGGGC TCCAATGGCG CTTTCTACAA GGCATTTGTA 
AAGGATGTTC ATGAAGATTC AATAACAGTT GCATTTGAAA ACAACTGGCA GCCTGATAGG 
CAGATTCCAT TTCATGATGT CAGATTCCCA CCTCCTGTAG GTTATAATAA AGATATAAAT 
GAAAGTGATG AAGTTGAGGT GTATTCCAGA GCAAATGAAA AAGAGCCTTG CTGTTGGTGG 
TTAGCTAAAG TGAGGATGAT AAAGGGTGAG TTTTATGTGA TAGAATATGC AGCATGTGAT 
GCAACTTACA ATGAAATTGT CACAATTGAA CGTCTAAGAT CTGTTAATCC CAACAAACCT 
GCCACAAAAG ATACTTTCCA TAAGATCAAG CTGGATGTGC CAGAAGACTT ACGGCAAATG 
TGTGCCAAAG AGGCGGCACA TAAGGATTTT AAAAAGGCAG TTGGTGCCTT TTCTGTAACT 
TATGATCCAG AAAATTATCA GCTTGTCATT TTGTCCATCA ATGAAGTCAC CTCAAAGCGA 
GCACATATGC TGATTGACAT GCACTTTCGG AGTCTGCGCA CTAAGTTGTC TCTGATAATG 
AGAAATGAAG AAGCTAGTAA GCAGCTGGAG AGTTCAAGGC AGCTTGCCTC GAGATTTCAT 
GAACAGTTTA TCGTAAGAGA AGATCTGATG GGTCTAGCTA TTGGTACTCA TGGTGCTAAT 
ATTCAGCAAG CTAGAAAAGT ACCTGGGGTC ACTGCTATTG ATCTAGATGA AGATACCTGC 
ACATTTCATA TTTATGGAGA GGATCAGGAT GCAGTGAAAA AAGCTAGAAG CTTTCTCGAA 
TTTGCTGAAG ATGTAATACA AGTTCCAAGG AACTTAGTAG GCAAAGTAAT AGGAAAAAAT 
GGAAAGCTGA TTCAGGAGAT TGTGGACAAG TCAGGAGTTG TGAGGGTGAG GATTGAGGCT 
GAAAATGAGA AAAATGTTCC ACAAGAAGAG GAAATTATGC CACCAAATTC CCTTCCTTCC 
AATAATTCAA GGGTTGGACC TAATGCCCCA GAAGAAAAAA AACATTTAGA TATAAAGGAA 
AACAGCACCC ATTTTTCTCA ACCTAACAGT ACAAAAGTCC AGAGGGGTAT GGTACCATTT 
GTTTTTGTGG GAACAAAGGA CAGCATCGCT AATGCCACTG TTCTTTTGGA TTATCACCTG 
AACTATTTAA AGCTCCAACA GAGGAAGAGA GGGAGAGCTT CCTGCGCAGA GGAGACGGAC 
GGCGGCGTGG AGGGGGAGGA AGAGGACAAG GAGGAAGAGG ACGTGGAGGA GGCTTCAAAG 
GAAACGACGA TCACTCCCGA ACAGATAATC GTCCACGTAA TCCAAGAGAG GCTAAAGGAA 
GAACAACAGA TGGATCCCTT CAGATCAGAG TTGACTGCAA TAATGAAAGG AGTGTCCACA 
CTAAAACATT ACAGAATACC TCCAGTGAAG GTAGTCGGCT GCGCACGGGT AAAGATCGTA 
ACCAGAAGAA AGAGAAGCCA GACAGCGTGG ATGGTCAGCA ACCACTCGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Alternative splicing of exon 14 determines nuclear or cytoplasmic localisation of fmr1 protein isoforms.
Human molecular genetics5(1)95-102(1996 Jan)
Sittler A,Devys D,Weber C,Mandel JL

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FMR1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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