SIN3B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SIN3B
Entrez Gene ID	23309
Full Name	SIN3 transcription regulator family member B
General protein information	Preferred Names SIN3 transcription regulator family member B Names paired amphipathic helix protein Sin3b SIN3 homolog B, transcriptional regulator SIN3 transcription regulator homolog B histone deacetylase complex subunit Sin3b transcriptional corepressor Sin3b
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.11
Disorder MIM:	607777

mRNA and Protein(s)

mRNA	Protein	Name
NM_001297595.2	NP_001284524.1	paired amphipathic helix protein Sin3b isoform 2
NM_015260.3	NP_056075.1	paired amphipathic helix protein Sin3b isoform 1
XM_006722704.1	XP_006722767.1	paired amphipathic helix protein Sin3b isoform X1
NM_001297595.1	NP_001284524.1	paired amphipathic helix protein Sin3b isoform 2
NM_001297597.1	NP_001284526.1	paired amphipathic helix protein Sin3b isoform 3
NM_015260.4	NP_056075.1	paired amphipathic helix protein Sin3b isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	SIN3B	NP_056075.1
Pan troglodytes (chimpanzee)	SIN3B	XP_512485.2
Bos taurus (cattle)	SIN3B	XP_003586291.1
Gallus gallus (chicken)	SIN3B	XP_418257.4
Canis lupus familiaris (dog)	SIN3B	XP_852728.2
Mus musculus (house mouse)	Sin3b	NP_033214.2
Xenopus tropicalis (tropical clawed frog)	sin3b	NP_001072289.1
	SIN3B	XP_002801166.1
Danio rerio (zebrafish)	sin3b	NP_001038410.1

Gene Ontology
Bibliography

Related articles in PubMed

Chromatin-Associated Protein SIN3B Prevents Prostate Cancer Progression by Inducing Senescence.
Bainor AJ, Deng FM, Wang Y, Lee P, Cantor DJ, Logan SK, David G
Cancer research77(19)5339-5348(2017 Oct)

SIN3A and SIN3B differentially regulate breast cancer metastasis.
Lewis MJ, Liu J, Libby EF, Lee M, Crawford NP, Hurst DR
Oncotarget7(48)78713-78725(2016 Nov)

Stress-mediated Sin3B activation leads to negative regulation of subset of p53 target genes.
Kadamb R, Mittal S, Bansal N, Saluja D
Bioscience reports35(4)(2015 Jun)

pH might play a role in regulating the function of paired amphipathic helices domains of human Sin3B by altering structure and thermodynamic stability.
Hasan T, Ali M, Saluja D, Singh LR
Biochemistry. Biokhimiia80(4)424-32(2015 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Low SIN3B expression is associated with Prostate Cancer Progression.
Title: Chromatin-Associated Protein SIN3B Prevents Prostate Cancer Progression by Inducing Senescence.

these results suggest that stress-induced Sin3B activation is p53-dependent and is essential for p53-mediated repression of its selective target genes.
Title: Stress-mediated Sin3B activation leads to negative regulation of subset of p53 target genes.

The study suggests that the difference in the conformation of native state structure or structural flexibility of the paired amphi pathic helices (PAH) domains of Sin3B might be responsible for interacting with specific binding partners.
Title: pH might play a role in regulating the function of paired amphipathic helices domains of human Sin3B by altering structure and thermodynamic stability.

A conserved Myc region (amino acids 186-203) is required for the interaction with Sin3 proteins. Histone deacetylase 1 is recruited to Myc-Sin3b complexes, and its deacetylase activity is required for the effects of Sin3b on Myc.
Title: Sin3b interacts with Myc and decreases Myc levels.

this study highlights an essential role for Sin3B in IFN-c induced COL1A2 repression in smooth muscle cells.
Title: Sin3B mediates collagen type I gene repression by interferon gamma in vascular smooth muscle cells.

The following SIN3B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SIN3B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu51514	XM_006722704.1 Latest version!	Homo sapiens SIN3 transcription regulator family member B (SIN3B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu28827	NM_001297597.1 Latest version!	Homo sapiens SIN3 transcription regulator family member B (SIN3B), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu28806	NM_001297595.2 Latest version!	Homo sapiens SIN3 transcription regulator family member B (SIN3B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00
OHu28835	NM_015260.4 Latest version!	Homo sapiens SIN3 transcription regulator family member B (SIN3B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00
View Old Accession Versions >>
OHu28806	NM_001297595.1	Homo sapiens SIN3 transcription regulator family member B (SIN3B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00
OHu28835	NM_015260.3	Homo sapiens SIN3 transcription regulator family member B (SIN3B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SIN3B ( XM_006722704.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_006722767.1 Homo sapiens SIN3 transcription regulator family member B (SIN3B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu51514
Clone ID Related Accession (Same CDS sequence)	XM_006722704.1
Accession Version	XM_006722704.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1938bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	paired amphipathic helix protein Sin3b isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGCCGG AAGACCAGGA GAAGTTCCGG CTGGACGACT CCCTGGGAGG CACGTCGGAG 
GTGATCCAGC GCCGTGCCAT TTATCGCATC TATGGCGACA AGGCCCCGGA GATCATCGAG 
AGCCTCAAGA AGAACCCTGT CACCGCTGTC CCCGTTGTCC TGAAAAGACT GAAGGCCAAG 
GAAGAGGAGT GGCGGGAGGC CCAGCAGGGC TTCAACAAGA TCTGGCGGGA GCAGTATGAG 
AAGGCGTACC TCAAGTCCCT TGACCACCAG GCTGTGAACT TCAAGCAGAA CGACACCAAG 
GCCCTGCGCT CCAAGAGCTT GCTCAACGAG ATCGAGAGCG TCTACGACGA GCACCAGGAG 
CAGCACTCGG AGGGCCGCAG TGCCCCCTCT AGCGAGCCGC ACCTCATCTT TGTGTACGAG 
GACCGGCAGA TCCTGGAGGA CGCAGCAGCG CTCATCAGCT ACTACGTGAA GCGGCAGCCG 
GCCATCCAGA AGGAGGACCA GGGCACCATC CACCAGCTGC TGCACCAGTT CGTGCCCAGC 
CTCTTCTTCT CTCAGCAGCT GGACCTGGGC GCCTCCGAGG AGTCAGCTGA TGAGGACCGG 
GACAGCCCCC AGGGGCAGAC CACAGACCCC AGTGAGCGGA AGAAGCCGGC GCCAGGACCC 
CACAGTAGCC CCCCAGAGGA GAAGGGGGCC TTCGGGGATG CCCCGGCCAC TGAGCAGCCA 
CCCCTGCCGC CCCCAGCCCC GCACAAGCCC CTGGACGATG TCTACAGCCT ATTTTTTGCC 
AACAACAACT GGTACTTCTT CCTGCGCCTG CACCAGACCC TGTGCTCCAG GCTGCTGAAG 
ATCTACCGCC AGGCGCAGAA GCAGCTTCTG GAGTATCGGA CCGAGAAGGA GCGGGAGAAG 
CTGCTGTGTG AGGGCCGCAG GGAGAAGGGC AGCGACCCCG CCATGGAGCT GCGGCTGAAG 
CAGCCCAGTG AAGTGGAGCT GGAGGAGTAC TACCCGGCCT TCCTGGACAT GGTGCGGAGC 
CTGCTGGAGG GCAGCATCGA CCCCACGCAG TACGAGGACA CCCTACGCGA GATGTTCACC 
ATCCATGCCT ACGTGGGCTT CACCATGGAC AAGCTGGTGC AGAACATTGC GCGGCAGCTG 
CACCACCTCG TGAGCGATGA CGTCTGCCTG AAGGTGGTGG AGCTCTACCT GAACGAGAAG 
AAGCGGGGTG CCGCTGGTGG GAACCTGTCC TCCCGCTGCG TCCGCGCTGC TAGGGAGACC 
AGCTACCAGT GGAAGGCTGA GCGCTGCATG GCCGACGAGA ACTGCTTCAA GGTGATGTTC 
CTGCAGCGCA AAGGGCAGGT GATCATGACC ATCGAGCTCC TGGACACCGA GGAGGCCCAG 
ACGGAGGACC CTGTGGAGGT CCAGCACCTG GCTCGGTACG TGGAGCAGTA TGTGGGGACC 
GAGGGCGCGT CCAGCTCGCC CACTGAGGGC TTCCTCCTGA AACCTGTGTT CCTGCAGAGG 
AACCTCAAGA AGTTCCGCCG CCGGTGGCAG AGCGAGCAGG CGCGGGCCCT GCGCGGTGAG 
GCCAGGAGCT CCTGGAAGCG GCTGGTGGGC GTGGAGAGCG CCTGCGACGT GGACTGCCGC 
TTCAAGCTCA GCACTCACAA GATGGTGTTC ATCGTGAACT CCGAGGACTA CATGTACCGT 
CGCGGGACCC TCTGCCGGGC CAAGCAGGTG CAGCCCCTGG TCCTGCTCCG CCACCACCAG 
CACTTTGAGG AGTGGCACAG CCGCTGGCTG GAGGACAATG TGACGGTGGA GGCGGCTAGC 
CTGGTGCAGG ACTGGCTGAT GGGTGAGGAG GACGAGGACA TGGTACCCTG CAAGACGCTG 
TGTGAGACAG TGCACGTGCA CGGCCTGCCC GTGACCCGCT ACCGCGTGCA GTACAGCCGC 
CGCCCGGCCT CGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006722767.1
CDS	201..2138
Translation	MAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCETVHVHGLPVTRYRVQYSRRPASP

Target ORF information:

RefSeq Version	XM_006722704.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SIN3 transcription regulator family member B (SIN3B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006722704.1

ORF Insert Sequence:

ATGGCGCCGG AAGACCAGGA GAAGTTCCGG CTGGACGACT CCCTGGGAGG CACGTCGGAG 
GTGATCCAGC GCCGTGCCAT TTATCGCATC TATGGCGACA AGGCCCCGGA GATCATCGAG 
AGCCTCAAGA AGAACCCTGT CACCGCTGTC CCCGTTGTCC TGAAAAGACT GAAGGCCAAG 
GAAGAGGAGT GGCGGGAGGC CCAGCAGGGC TTCAACAAGA TCTGGCGGGA GCAGTATGAG 
AAGGCGTACC TCAAGTCCCT TGACCACCAG GCTGTGAACT TCAAGCAGAA CGACACCAAG 
GCCCTGCGCT CCAAGAGCTT GCTCAACGAG ATCGAGAGCG TCTACGACGA GCACCAGGAG 
CAGCACTCGG AGGGCCGCAG TGCCCCCTCT AGCGAGCCGC ACCTCATCTT TGTGTACGAG 
GACCGGCAGA TCCTGGAGGA CGCAGCAGCG CTCATCAGCT ACTACGTGAA GCGGCAGCCG 
GCCATCCAGA AGGAGGACCA GGGCACCATC CACCAGCTGC TGCACCAGTT CGTGCCCAGC 
CTCTTCTTCT CTCAGCAGCT GGACCTGGGC GCCTCCGAGG AGTCAGCTGA TGAGGACCGG 
GACAGCCCCC AGGGGCAGAC CACAGACCCC AGTGAGCGGA AGAAGCCGGC GCCAGGACCC 
CACAGTAGCC CCCCAGAGGA GAAGGGGGCC TTCGGGGATG CCCCGGCCAC TGAGCAGCCA 
CCCCTGCCGC CCCCAGCCCC GCACAAGCCC CTGGACGATG TCTACAGCCT ATTTTTTGCC 
AACAACAACT GGTACTTCTT CCTGCGCCTG CACCAGACCC TGTGCTCCAG GCTGCTGAAG 
ATCTACCGCC AGGCGCAGAA GCAGCTTCTG GAGTATCGGA CCGAGAAGGA GCGGGAGAAG 
CTGCTGTGTG AGGGCCGCAG GGAGAAGGGC AGCGACCCCG CCATGGAGCT GCGGCTGAAG 
CAGCCCAGTG AAGTGGAGCT GGAGGAGTAC TACCCGGCCT TCCTGGACAT GGTGCGGAGC 
CTGCTGGAGG GCAGCATCGA CCCCACGCAG TACGAGGACA CCCTACGCGA GATGTTCACC 
ATCCATGCCT ACGTGGGCTT CACCATGGAC AAGCTGGTGC AGAACATTGC GCGGCAGCTG 
CACCACCTCG TGAGCGATGA CGTCTGCCTG AAGGTGGTGG AGCTCTACCT GAACGAGAAG 
AAGCGGGGTG CCGCTGGTGG GAACCTGTCC TCCCGCTGCG TCCGCGCTGC TAGGGAGACC 
AGCTACCAGT GGAAGGCTGA GCGCTGCATG GCCGACGAGA ACTGCTTCAA GGTGATGTTC 
CTGCAGCGCA AAGGGCAGGT GATCATGACC ATCGAGCTCC TGGACACCGA GGAGGCCCAG 
ACGGAGGACC CTGTGGAGGT CCAGCACCTG GCTCGGTACG TGGAGCAGTA TGTGGGGACC 
GAGGGCGCGT CCAGCTCGCC CACTGAGGGC TTCCTCCTGA AACCTGTGTT CCTGCAGAGG 
AACCTCAAGA AGTTCCGCCG CCGGTGGCAG AGCGAGCAGG CGCGGGCCCT GCGCGGTGAG 
GCCAGGAGCT CCTGGAAGCG GCTGGTGGGC GTGGAGAGCG CCTGCGACGT GGACTGCCGC 
TTCAAGCTCA GCACTCACAA GATGGTGTTC ATCGTGAACT CCGAGGACTA CATGTACCGT 
CGCGGGACCC TCTGCCGGGC CAAGCAGGTG CAGCCCCTGG TCCTGCTCCG CCACCACCAG 
CACTTTGAGG AGTGGCACAG CCGCTGGCTG GAGGACAATG TGACGGTGGA GGCGGCTAGC 
CTGGTGCAGG ACTGGCTGAT GGGTGAGGAG GACGAGGACA TGGTACCCTG CAAGACGCTG 
TGTGAGACAG TGCACGTGCA CGGCCTGCCC GTGACCCGCT ACCGCGTGCA GTACAGCCGC 
CGCCCGGCCT CGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SIN3B ( NM_001297597.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001284526.1 Homo sapiens SIN3 transcription regulator family member B (SIN3B), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu28827
Clone ID Related Accession (Same CDS sequence)	NM_001297597.1
Accession Version	NM_001297597.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2163bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-18
Organism	Homo sapiens(human)
Product	paired amphipathic helix protein Sin3b isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC332740.1, AK295618.1, AB014600.2 and AY706204.1. Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at an alternate start codon, compared to variant 1. It encodes isoform 3, which is shorter and has a distinct N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK295618.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGCGTC ATTCACGGCA TTTCCTCTTG GTGCAGGTAC TGAACGACAC CTGGGTCTCC 
TTCCCTTCCT GGTCTGAGGA CTCCACGTTC GTCAGCTCCA AGAAGACACC GTACGAGGAG 
CAGCTTCACC GCTGTGAGGA CGAGCGCTTC GAGTTAGACG TTGTCCTGGA GACGAACCTG 
GCCACAATCC GTGTGTTGGA AAGTGTGCAG AAGAAGCTGT CTCGGATGGC GCCGGAAGAC 
CAGGAGAAGT TCCGGCTGGA CGACTCCCTG GGAGGCACGT CGGAGGTGAT CCAGCGCCGT 
GCCATTTATC GCATCTATGG CGACAAGGCC CCGGAGATCA TCGAGAGCCT CAAGAAGAAC 
CCTGTCACCG CTGTCCCCGT TGTCCTGAAA AGACTGAAGG CCAAGGAAGA GGAGTGGCGG 
GAGGCCCAGC AGGGCTTCAA CAAGATCTGG CGGGAGCAGT ATGAGAAGGC GTACCTCAAG 
TCCCTTGACC ACCAGGCTGT GAACTTCAAG CAGAACGACA CCAAGGCCCT GCGCTCCAAG 
AGCTTGCTCA ACGAGATCGA GAGCGTCTAC GACGAGCACC AGGAGCAGCA CTCGGAGGGC 
CGCAGTGCCC CCTCTAGCGA GCCGCACCTC ATCTTTGTGT ACGAGGACCG GCAGATCCTG 
GAGGACGCAG CAGCGCTCAT CAGCTACTAC GTGAAGCGGC AGCCGGCCAT CCAGAAGGAG 
GACCAGGGCA CCATCCACCA GCTGCTGCAC CAGTTCGTGC CCAGCCTCTT CTTCTCTCAG 
CAGCTGGACC TGGGCGCCTC CGAGGAGTCA GCTGATGAGG ACCGGGACAG CCCCCAGGGG 
CAGACCACAG ACCCCAGTGA GCGGAAGAAG CCGGCGCCAG GACCCCACAG TAGCCCCCCA 
GAGGAGAAGG GGGCCTTCGG GGATGCCCCG GCCACTGAGC AGCCACCCCT GCCGCCCCCA 
GCCCCGCACA AGCCCCTGGA CGATGTCTAC AGCCTATTTT TTGCCAACAA CAACTGGTAC 
TTCTTCCTGC GCCTGCACCA GACCCTGTGC TCCAGGCTGC TGAAGATCTA CCGCCAGGCG 
CAGAAGCAGC TTCTGGAGTA TCGGACCGAG AAGGAGCGGG AGAAGCTGCT GTGTGAGGGC 
CGCAGGGAGA AGGGCAGCGA CCCCGCCATG GAGCTGCGGC TGAAGCAGCC CAGTGAAGTG 
GAGCTGGAGG AGTACTACCC GGCCTTCCTG GACATGGTGC GGAGCCTGCT GGAGGGCAGC 
ATCGACCCCA CGCAGTACGA GGACACCCTA CGCGAGATGT TCACCATCCA TGCCTACGTG 
GGCTTCACCA TGGACAAGCT GGTGCAGAAC ATTGCGCGGC AGCTGCACCA CCTCGTGAGC 
GATGACGTCT GCCTGAAGGT GGTGGAGCTC TACCTGAACG AGAAGAAGCG GGGTGCCGCT 
GGTGGGAACC TGTCCTCCCG CTGCGTCCGC GCTGCTAGGG AGACCAGCTA CCAGTGGAAG 
GCTGAGCGCT GCATGGCCGA CGAGAACTGC TTCAAGGTGA TGTTCCTGCA GCGCAAAGGG 
CAGGTGATCA TGACCATCGA GCTCCTGGAC ACCGAGGAGG CCCAGACGGA GGACCCTGTG 
GAGGTCCAGC ACCTGGCTCG GTACGTGGAG CAGTATGTGG GGACCGAGGG CGCGTCCAGC 
TCGCCCACTG AGGGCTTCCT CCTGAAACCT GTGTTCCTGC AGAGGAACCT CAAGAAGTTC 
CGCCGCCGGT GGCAGAGCGA GCAGGCGCGG GCCCTGCGCG GTGAGGCCAG GAGCTCCTGG 
AAGCGGCTGG TGGGCGTGGA GAGCGCCTGC GACGTGGACT GCCGCTTCAA GCTCAGCACT 
CACAAGATGG TGTTCATCGT GAACTCCGAG GACTACATGT ACCGTCGCGG GACCCTCTGC 
CGGGCCAAGC AGGTGCAGCC CCTGGTCCTG CTCCGCCACC ACCAGCACTT TGAGGAGTGG 
CACAGCCGCT GGCTGGAGGA CAATGTGACG GTGGAGGCGG CTAGCCTGGT GCAGGACTGG 
CTGATGGGTG AGGAGGACGA GGACATGGTA CCCTGCAAGA CGCTGTGTGA GACAGTGCAC 
GTGCACGGCC TGCCCGTGAC CCGCTACCGC GTGCAGTACA GCCGCCGCCC GGCCTCGCCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001284526.1
CDS	371..2533
Translation	MQRHSRHFLLVQVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCETVHVHGLPVTRYRVQYSRRPASP

Target ORF information:

RefSeq Version	NM_001297597.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SIN3 transcription regulator family member B (SIN3B), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001297597.1

ORF Insert Sequence:

ATGCAGCGTC ATTCACGGCA TTTCCTCTTG GTGCAGGTAC TGAACGACAC CTGGGTCTCC 
TTCCCTTCCT GGTCTGAGGA CTCCACGTTC GTCAGCTCCA AGAAGACACC GTACGAGGAG 
CAGCTTCACC GCTGTGAGGA CGAGCGCTTC GAGTTAGACG TTGTCCTGGA GACGAACCTG 
GCCACAATCC GTGTGTTGGA AAGTGTGCAG AAGAAGCTGT CTCGGATGGC GCCGGAAGAC 
CAGGAGAAGT TCCGGCTGGA CGACTCCCTG GGAGGCACGT CGGAGGTGAT CCAGCGCCGT 
GCCATTTATC GCATCTATGG CGACAAGGCC CCGGAGATCA TCGAGAGCCT CAAGAAGAAC 
CCTGTCACCG CTGTCCCCGT TGTCCTGAAA AGACTGAAGG CCAAGGAAGA GGAGTGGCGG 
GAGGCCCAGC AGGGCTTCAA CAAGATCTGG CGGGAGCAGT ATGAGAAGGC GTACCTCAAG 
TCCCTTGACC ACCAGGCTGT GAACTTCAAG CAGAACGACA CCAAGGCCCT GCGCTCCAAG 
AGCTTGCTCA ACGAGATCGA GAGCGTCTAC GACGAGCACC AGGAGCAGCA CTCGGAGGGC 
CGCAGTGCCC CCTCTAGCGA GCCGCACCTC ATCTTTGTGT ACGAGGACCG GCAGATCCTG 
GAGGACGCAG CAGCGCTCAT CAGCTACTAC GTGAAGCGGC AGCCGGCCAT CCAGAAGGAG 
GACCAGGGCA CCATCCACCA GCTGCTGCAC CAGTTCGTGC CCAGCCTCTT CTTCTCTCAG 
CAGCTGGACC TGGGCGCCTC CGAGGAGTCA GCTGATGAGG ACCGGGACAG CCCCCAGGGG 
CAGACCACAG ACCCCAGTGA GCGGAAGAAG CCGGCGCCAG GACCCCACAG TAGCCCCCCA 
GAGGAGAAGG GGGCCTTCGG GGATGCCCCG GCCACTGAGC AGCCACCCCT GCCGCCCCCA 
GCCCCGCACA AGCCCCTGGA CGATGTCTAC AGCCTATTTT TTGCCAACAA CAACTGGTAC 
TTCTTCCTGC GCCTGCACCA GACCCTGTGC TCCAGGCTGC TGAAGATCTA CCGCCAGGCG 
CAGAAGCAGC TTCTGGAGTA TCGGACCGAG AAGGAGCGGG AGAAGCTGCT GTGTGAGGGC 
CGCAGGGAGA AGGGCAGCGA CCCCGCCATG GAGCTGCGGC TGAAGCAGCC CAGTGAAGTG 
GAGCTGGAGG AGTACTACCC GGCCTTCCTG GACATGGTGC GGAGCCTGCT GGAGGGCAGC 
ATCGACCCCA CGCAGTACGA GGACACCCTA CGCGAGATGT TCACCATCCA TGCCTACGTG 
GGCTTCACCA TGGACAAGCT GGTGCAGAAC ATTGCGCGGC AGCTGCACCA CCTCGTGAGC 
GATGACGTCT GCCTGAAGGT GGTGGAGCTC TACCTGAACG AGAAGAAGCG GGGTGCCGCT 
GGTGGGAACC TGTCCTCCCG CTGCGTCCGC GCTGCTAGGG AGACCAGCTA CCAGTGGAAG 
GCTGAGCGCT GCATGGCCGA CGAGAACTGC TTCAAGGTGA TGTTCCTGCA GCGCAAAGGG 
CAGGTGATCA TGACCATCGA GCTCCTGGAC ACCGAGGAGG CCCAGACGGA GGACCCTGTG 
GAGGTCCAGC ACCTGGCTCG GTACGTGGAG CAGTATGTGG GGACCGAGGG CGCGTCCAGC 
TCGCCCACTG AGGGCTTCCT CCTGAAACCT GTGTTCCTGC AGAGGAACCT CAAGAAGTTC 
CGCCGCCGGT GGCAGAGCGA GCAGGCGCGG GCCCTGCGCG GTGAGGCCAG GAGCTCCTGG 
AAGCGGCTGG TGGGCGTGGA GAGCGCCTGC GACGTGGACT GCCGCTTCAA GCTCAGCACT 
CACAAGATGG TGTTCATCGT GAACTCCGAG GACTACATGT ACCGTCGCGG GACCCTCTGC 
CGGGCCAAGC AGGTGCAGCC CCTGGTCCTG CTCCGCCACC ACCAGCACTT TGAGGAGTGG 
CACAGCCGCT GGCTGGAGGA CAATGTGACG GTGGAGGCGG CTAGCCTGGT GCAGGACTGG 
CTGATGGGTG AGGAGGACGA GGACATGGTA CCCTGCAAGA CGCTGTGTGA GACAGTGCAC 
GTGCACGGCC TGCCCGTGAC CCGCTACCGC GTGCAGTACA GCCGCCGCCC GGCCTCGCCC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SIN3B ( NM_001297595.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001284524.1 Homo sapiens SIN3 transcription regulator family member B (SIN3B), transcript variant 2, mRNA.

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CloneID	OHu28806
Clone ID Related Accession (Same CDS sequence)	NM_001297595.2 , NM_001297595.1
Accession Version	NM_001297595.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3393bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-17
Organism	Homo sapiens(human)
Product	paired amphipathic helix protein Sin3b isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HY055983.1, AB014600.2 and AY706204.1. On Jun 2, 2019 this sequence version replaced NM_001297595.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform 2, which lacks an internal segment and is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB014600.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGCACG CTGGCGGTGG CAGCGGTGGC AGCGGTGCCG GCGGCCCCGC GGGCCGGGGG 
CTGAGCGGCG CCCGCTGGGG TCGCTCGGGC TCCGCAGGCC ACGAGAAGCT GCCGGTGCAC 
GTAGAAGACG CCCTCACCTA TCTGGACCAG GTGAAGATCC GCTTTGGCAG CGACCCTGCC 
ACCTACAACG GCTTCCTGGA GATCATGAAG GAGTTCAAAA GCCAGAGCAT CGATACTCCT 
GGAGTCATCA GACGTGTCTC GCAGCTCTTC CACGAGCACC CTGACCTCAT TGTTGGATTC 
AACGCTTTTC TTCCCCTCGG ATATAGAATA GACATTCCCA AGAATGGCAA GTTAAACATA 
CAGTCGCCTC TGACAAGCCA GGAGAATTCG CACAACCACG GGGACGGTGC AGAGGACTTC 
AAGCAGCAGG TGCCGTATAA AGAGGACAAA CCCCAGGTGC CCCTGGAGTC CGATTCCGTG 
GAATTCAACA ACGCCATCAG CTATGTGAAT AAGATTAAAA CCCGCTTCCT AGACCACCCA 
GAAATCTACA GGTCATTCCT GGAGATCCTG CACACGTACC AGAAGGAGCA GCTGAACACG 
AGGGGCCGGC CATTCCGAGG CATGTCTGAA GAGGAGGTGT TCACCGAGGT GGCCAACCTC 
TTCCGGGGCC AGGAGGACCT GCTCTCAGAG TTTGGACAGT TCCTGCCCGA AGCCAAGCGG 
TCTCTGTTCA CAGGAAACGG GCCGTGCGAG ATGCACAGCG TGCAGAAGAA CGAGCACGAC 
AAGACCCCGG AGCACAGCAG GAAGCGCTCC CGGCCCTCGC TCCTCCGCCC CGTGTCTGCA 
CCCGCCAAGA AAAAAATGAA ACTTCGTGGT ACCAAAGACC TGTCCATCGC TGCAGTGGGG 
AAGTACGGGA CTCTGCAGGA ATTTTCTTTC TTTGACAAGG TCCGCCGGGT GCTGAAGAGC 
CAGGAGGTGT ATGAAAACTT CCTCCGCTGC ATCGCACTCT TCAACCAGGA GCTGGTGTCT 
GGCTCTGAGC TCCTGCAGCT CGTCAGCCCA TTTCTGGGGA AATTTCCAGA ACTCTTTGCA 
CAGTTCAAGT CCTTCCTGGG GGTAAAAGAG CTGTCCTTCG CGCCACCCAT GAGCGACAGA 
TCCGGGGACG GGATAAGCCG GGAAATTGAT TATGCATCCT GCAAGCGCAT AGGATCCAGC 
TACCGGGCAC TCCCCAAAAC CTACCAGCAG CCCAAGTGCA GTGGGAGGAC AGCCATCTGC 
AAGGAGGTAC TGAACGACAC CTGGGTCTCC TTCCCTTCCT GGTCTGAGGA CTCCACGTTC 
GTCAGCTCCA AGAAGACACC GTACGAGGAG CAGCTTCACC GCTGTGAGGA CGAGCGCTTC 
GAGTTAGACG TTGTCCTGGA GACGAACCTG GCCACAATCC GTGTGTTGGA AAGTGTGCAG 
AAGAAGCTGT CTCGGATGGC GCCGGAAGAC CAGGAGAAGT TCCGGCTGGA CGACTCCCTG 
GGAGGCACGT CGGAGGTGAT CCAGCGCCGT GCCATTTATC GCATCTATGG CGACAAGGCC 
CCGGAGATCA TCGAGAGCCT CAAGAAGAAC CCTGTCACCG CTGTCCCCGT TGTCCTGAAA 
AGACTGAAGG CCAAGGAAGA GGAGTGGCGG GAGGCCCAGC AGGGCTTCAA CAAGATCTGG 
CGGGAGCAGT ATGAGAAGGC GTACCTCAAG TCCCTTGACC ACCAGGCTGT GAACTTCAAG 
CAGAACGACA CCAAGGCCCT GCGCTCCAAG AGCTTGCTCA ACGAGATCGA GAGCGTCTAC 
GACGAGCACC AGGAGCAGCA CTCGGAGGGC CGCAGTGCCC CCTCTAGCGA GCCGCACCTC 
ATCTTTGTGT ACGAGGACCG GCAGATCCTG GAGGACGCAG CAGCGCTCAT CAGCTACTAC 
GTGAAGCGGC AGCCGGCCAT CCAGAAGGAG GACCAGGGCA CCATCCACCA GCTGCTGCAC 
CAGTTCGTGC CCAGCCTCTT CTTCTCTCAG CAGCTGGACC TGGGCGCCTC CGAGGAGTCA 
GCTGATGAGG ACCGGGACAG CCCCCAGGGG CAGACCACAG ACCCCAGTGA GCGGAAGAAG 
CCGGCGCCAG GACCCCACAG TAGCCCCCCA GAGGAGAAGG GGGCCTTCGG GGATGCCCCG 
GCCACTGAGC AGCCACCCCT GCCGCCCCCA GCCCCGCACA AGCCCCTGGA CGATGTCTAC 
AGCCTATTTT TTGCCAACAA CAACTGGTAC TTCTTCCTGC GCCTGCACCA GACCCTGTGC 
TCCAGGCTGC TGAAGATCTA CCGCCAGGCG CAGAAGCAGC TTCTGGAGTA TCGGACCGAG 
AAGGAGCGGG AGAAGCTGCT GTGTGAGGGC CGCAGGGAGA AGGGCAGCGA CCCCGCCATG 
GAGCTGCGGC TGAAGCAGCC CAGTGAAGTG GAGCTGGAGG AGTACTACCC GGCCTTCCTG 
GACATGGTGC GGAGCCTGCT GGAGGGCAGC ATCGACCCCA CGCAGTACGA GGACACCCTA 
CGCGAGATGT TCACCATCCA TGCCTACGTG GGCTTCACCA TGGACAAGCT GGTGCAGAAC 
ATTGCGCGGC AGCTGCACCA CCTCGTGAGC GATGACGTCT GCCTGAAGGT GGTGGAGCTC 
TACCTGAACG AGAAGAAGCG GGGTGCCGCT GGTGGGAACC TGTCCTCCCG CTGCGTCCGC 
GCTGCTAGGG AGACCAGCTA CCAGTGGAAG GCTGAGCGCT GCATGGCCGA CGAGAACTGC 
TTCAAGGTGA TGTTCCTGCA GCGCAAAGGG CAGGTGATCA TGACCATCGA GCTCCTGGAC 
ACCGAGGAGG CCCAGACGGA GGACCCTGTG GAGGTCCAGC ACCTGGCTCG GTACGTGGAG 
CAGTATGTGG GGACCGAGGG CGCGTCCAGC TCGCCCACTG AGGGCTTCCT CCTGAAACCT 
GTGTTCCTGC AGAGGAACCT CAAGAAGTTC CGCCGCCGGT GGCAGAGCGA GCAGGCGCGG 
GCCCTGCGCG GTGAGGCCAG GAGCTCCTGG AAGCGGCTGG TGGGCGTGGA GAGCGCCTGC 
GACGTGGACT GCCGCTTCAA GCTCAGCACT CACAAGATGG TGTTCATCGT GAACTCCGAG 
GACTACATGT ACCGTCGCGG GACCCTCTGC CGGGCCAAGC AGGTGCAGCC CCTGGTCCTG 
CTCCGCCACC ACCAGCACTT TGAGGAGTGG CACAGCCGCT GGCTGGAGGA CAATGTGACG 
GTGGAGGCGG CTAGCCTGGT GCAGGACTGG CTGATGGGTG AGGAGGACGA GGACATGGTA 
CCCTGCAAGA CGCTGTGTGA GACAGTGCAC GTGCACGGCC TGCCCGTGAC CCGCTACCGC 
GTGCAGTACA GCCGCCGCCC GGCCTCGCCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001284524.1
CDS	24..3416
Translation	MAHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLTSQENSHNHGDGAEDFKQQVPYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKEVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCETVHVHGLPVTRYRVQYSRRPASP

Target ORF information:

RefSeq Version	NM_001297595.2
Organism	Homo sapiens(human)
Definition	Homo sapiens SIN3 transcription regulator family member B (SIN3B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001297595.2

ORF Insert Sequence:

ATGGCGCACG CTGGCGGTGG CAGCGGTGGC AGCGGTGCCG GCGGCCCCGC GGGCCGGGGG 
CTGAGCGGCG CCCGCTGGGG TCGCTCGGGC TCCGCAGGCC ACGAGAAGCT GCCGGTGCAC 
GTAGAAGACG CCCTCACCTA TCTGGACCAG GTGAAGATCC GCTTTGGCAG CGACCCTGCC 
ACCTACAACG GCTTCCTGGA GATCATGAAG GAGTTCAAAA GCCAGAGCAT CGATACTCCT 
GGAGTCATCA GACGTGTCTC GCAGCTCTTC CACGAGCACC CTGACCTCAT TGTTGGATTC 
AACGCTTTTC TTCCCCTCGG ATATAGAATA GACATTCCCA AGAATGGCAA GTTAAACATA 
CAGTCGCCTC TGACAAGCCA GGAGAATTCG CACAACCACG GGGACGGTGC AGAGGACTTC 
AAGCAGCAGG TGCCGTATAA AGAGGACAAA CCCCAGGTGC CCCTGGAGTC CGATTCCGTG 
GAATTCAACA ACGCCATCAG CTATGTGAAT AAGATTAAAA CCCGCTTCCT AGACCACCCA 
GAAATCTACA GGTCATTCCT GGAGATCCTG CACACGTACC AGAAGGAGCA GCTGAACACG 
AGGGGCCGGC CATTCCGAGG CATGTCTGAA GAGGAGGTGT TCACCGAGGT GGCCAACCTC 
TTCCGGGGCC AGGAGGACCT GCTCTCAGAG TTTGGACAGT TCCTGCCCGA AGCCAAGCGG 
TCTCTGTTCA CAGGAAACGG GCCGTGCGAG ATGCACAGCG TGCAGAAGAA CGAGCACGAC 
AAGACCCCGG AGCACAGCAG GAAGCGCTCC CGGCCCTCGC TCCTCCGCCC CGTGTCTGCA 
CCCGCCAAGA AAAAAATGAA ACTTCGTGGT ACCAAAGACC TGTCCATCGC TGCAGTGGGG 
AAGTACGGGA CTCTGCAGGA ATTTTCTTTC TTTGACAAGG TCCGCCGGGT GCTGAAGAGC 
CAGGAGGTGT ATGAAAACTT CCTCCGCTGC ATCGCACTCT TCAACCAGGA GCTGGTGTCT 
GGCTCTGAGC TCCTGCAGCT CGTCAGCCCA TTTCTGGGGA AATTTCCAGA ACTCTTTGCA 
CAGTTCAAGT CCTTCCTGGG GGTAAAAGAG CTGTCCTTCG CGCCACCCAT GAGCGACAGA 
TCCGGGGACG GGATAAGCCG GGAAATTGAT TATGCATCCT GCAAGCGCAT AGGATCCAGC 
TACCGGGCAC TCCCCAAAAC CTACCAGCAG CCCAAGTGCA GTGGGAGGAC AGCCATCTGC 
AAGGAGGTAC TGAACGACAC CTGGGTCTCC TTCCCTTCCT GGTCTGAGGA CTCCACGTTC 
GTCAGCTCCA AGAAGACACC GTACGAGGAG CAGCTTCACC GCTGTGAGGA CGAGCGCTTC 
GAGTTAGACG TTGTCCTGGA GACGAACCTG GCCACAATCC GTGTGTTGGA AAGTGTGCAG 
AAGAAGCTGT CTCGGATGGC GCCGGAAGAC CAGGAGAAGT TCCGGCTGGA CGACTCCCTG 
GGAGGCACGT CGGAGGTGAT CCAGCGCCGT GCCATTTATC GCATCTATGG CGACAAGGCC 
CCGGAGATCA TCGAGAGCCT CAAGAAGAAC CCTGTCACCG CTGTCCCCGT TGTCCTGAAA 
AGACTGAAGG CCAAGGAAGA GGAGTGGCGG GAGGCCCAGC AGGGCTTCAA CAAGATCTGG 
CGGGAGCAGT ATGAGAAGGC GTACCTCAAG TCCCTTGACC ACCAGGCTGT GAACTTCAAG 
CAGAACGACA CCAAGGCCCT GCGCTCCAAG AGCTTGCTCA ACGAGATCGA GAGCGTCTAC 
GACGAGCACC AGGAGCAGCA CTCGGAGGGC CGCAGTGCCC CCTCTAGCGA GCCGCACCTC 
ATCTTTGTGT ACGAGGACCG GCAGATCCTG GAGGACGCAG CAGCGCTCAT CAGCTACTAC 
GTGAAGCGGC AGCCGGCCAT CCAGAAGGAG GACCAGGGCA CCATCCACCA GCTGCTGCAC 
CAGTTCGTGC CCAGCCTCTT CTTCTCTCAG CAGCTGGACC TGGGCGCCTC CGAGGAGTCA 
GCTGATGAGG ACCGGGACAG CCCCCAGGGG CAGACCACAG ACCCCAGTGA GCGGAAGAAG 
CCGGCGCCAG GACCCCACAG TAGCCCCCCA GAGGAGAAGG GGGCCTTCGG GGATGCCCCG 
GCCACTGAGC AGCCACCCCT GCCGCCCCCA GCCCCGCACA AGCCCCTGGA CGATGTCTAC 
AGCCTATTTT TTGCCAACAA CAACTGGTAC TTCTTCCTGC GCCTGCACCA GACCCTGTGC 
TCCAGGCTGC TGAAGATCTA CCGCCAGGCG CAGAAGCAGC TTCTGGAGTA TCGGACCGAG 
AAGGAGCGGG AGAAGCTGCT GTGTGAGGGC CGCAGGGAGA AGGGCAGCGA CCCCGCCATG 
GAGCTGCGGC TGAAGCAGCC CAGTGAAGTG GAGCTGGAGG AGTACTACCC GGCCTTCCTG 
GACATGGTGC GGAGCCTGCT GGAGGGCAGC ATCGACCCCA CGCAGTACGA GGACACCCTA 
CGCGAGATGT TCACCATCCA TGCCTACGTG GGCTTCACCA TGGACAAGCT GGTGCAGAAC 
ATTGCGCGGC AGCTGCACCA CCTCGTGAGC GATGACGTCT GCCTGAAGGT GGTGGAGCTC 
TACCTGAACG AGAAGAAGCG GGGTGCCGCT GGTGGGAACC TGTCCTCCCG CTGCGTCCGC 
GCTGCTAGGG AGACCAGCTA CCAGTGGAAG GCTGAGCGCT GCATGGCCGA CGAGAACTGC 
TTCAAGGTGA TGTTCCTGCA GCGCAAAGGG CAGGTGATCA TGACCATCGA GCTCCTGGAC 
ACCGAGGAGG CCCAGACGGA GGACCCTGTG GAGGTCCAGC ACCTGGCTCG GTACGTGGAG 
CAGTATGTGG GGACCGAGGG CGCGTCCAGC TCGCCCACTG AGGGCTTCCT CCTGAAACCT 
GTGTTCCTGC AGAGGAACCT CAAGAAGTTC CGCCGCCGGT GGCAGAGCGA GCAGGCGCGG 
GCCCTGCGCG GTGAGGCCAG GAGCTCCTGG AAGCGGCTGG TGGGCGTGGA GAGCGCCTGC 
GACGTGGACT GCCGCTTCAA GCTCAGCACT CACAAGATGG TGTTCATCGT GAACTCCGAG 
GACTACATGT ACCGTCGCGG GACCCTCTGC CGGGCCAAGC AGGTGCAGCC CCTGGTCCTG 
CTCCGCCACC ACCAGCACTT TGAGGAGTGG CACAGCCGCT GGCTGGAGGA CAATGTGACG 
GTGGAGGCGG CTAGCCTGGT GCAGGACTGG CTGATGGGTG AGGAGGACGA GGACATGGTA 
CCCTGCAAGA CGCTGTGTGA GACAGTGCAC GTGCACGGCC TGCCCGTGAC CCGCTACCGC 
GTGCAGTACA GCCGCCGCCC GGCCTCGCCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SIN3B ( NM_001297595.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001284524.1 Homo sapiens SIN3 transcription regulator family member B (SIN3B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu28806
Clone ID Related Accession (Same CDS sequence)	NM_001297595.2 , NM_001297595.1
Accession Version	NM_001297595.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3393bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-15
Organism	Homo sapiens(human)
Product	paired amphipathic helix protein Sin3b isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HY055983.1, AB014600.2 and AY706204.1. On Jul 4, 2014 this sequence version replaced XM_005259832.2. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. It encodes isoform 2, which lacks an internal segment and is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB014600.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGCACG CTGGCGGTGG CAGCGGTGGC AGCGGTGCCG GCGGCCCCGC GGGCCGGGGG 
CTGAGCGGCG CCCGCTGGGG TCGCTCGGGC TCCGCAGGCC ACGAGAAGCT GCCGGTGCAC 
GTAGAAGACG CCCTCACCTA TCTGGACCAG GTGAAGATCC GCTTTGGCAG CGACCCTGCC 
ACCTACAACG GCTTCCTGGA GATCATGAAG GAGTTCAAAA GCCAGAGCAT CGATACTCCT 
GGAGTCATCA GACGTGTCTC GCAGCTCTTC CACGAGCACC CTGACCTCAT TGTTGGATTC 
AACGCTTTTC TTCCCCTCGG ATATAGAATA GACATTCCCA AGAATGGCAA GTTAAACATA 
CAGTCGCCTC TGACAAGCCA GGAGAATTCG CACAACCACG GGGACGGTGC AGAGGACTTC 
AAGCAGCAGG TGCCGTATAA AGAGGACAAA CCCCAGGTGC CCCTGGAGTC CGATTCCGTG 
GAATTCAACA ACGCCATCAG CTATGTGAAT AAGATTAAAA CCCGCTTCCT AGACCACCCA 
GAAATCTACA GGTCATTCCT GGAGATCCTG CACACGTACC AGAAGGAGCA GCTGAACACG 
AGGGGCCGGC CATTCCGAGG CATGTCTGAA GAGGAGGTGT TCACCGAGGT GGCCAACCTC 
TTCCGGGGCC AGGAGGACCT GCTCTCAGAG TTTGGACAGT TCCTGCCCGA AGCCAAGCGG 
TCTCTGTTCA CAGGAAACGG GCCGTGCGAG ATGCACAGCG TGCAGAAGAA CGAGCACGAC 
AAGACCCCGG AGCACAGCAG GAAGCGCTCC CGGCCCTCGC TCCTCCGCCC CGTGTCTGCA 
CCCGCCAAGA AAAAAATGAA ACTTCGTGGT ACCAAAGACC TGTCCATCGC TGCAGTGGGG 
AAGTACGGGA CTCTGCAGGA ATTTTCTTTC TTTGACAAGG TCCGCCGGGT GCTGAAGAGC 
CAGGAGGTGT ATGAAAACTT CCTCCGCTGC ATCGCACTCT TCAACCAGGA GCTGGTGTCT 
GGCTCTGAGC TCCTGCAGCT CGTCAGCCCA TTTCTGGGGA AATTTCCAGA ACTCTTTGCA 
CAGTTCAAGT CCTTCCTGGG GGTAAAAGAG CTGTCCTTCG CGCCACCCAT GAGCGACAGA 
TCCGGGGACG GGATAAGCCG GGAAATTGAT TATGCATCCT GCAAGCGCAT AGGATCCAGC 
TACCGGGCAC TCCCCAAAAC CTACCAGCAG CCCAAGTGCA GTGGGAGGAC AGCCATCTGC 
AAGGAGGTAC TGAACGACAC CTGGGTCTCC TTCCCTTCCT GGTCTGAGGA CTCCACGTTC 
GTCAGCTCCA AGAAGACACC GTACGAGGAG CAGCTTCACC GCTGTGAGGA CGAGCGCTTC 
GAGTTAGACG TTGTCCTGGA GACGAACCTG GCCACAATCC GTGTGTTGGA AAGTGTGCAG 
AAGAAGCTGT CTCGGATGGC GCCGGAAGAC CAGGAGAAGT TCCGGCTGGA CGACTCCCTG 
GGAGGCACGT CGGAGGTGAT CCAGCGCCGT GCCATTTATC GCATCTATGG CGACAAGGCC 
CCGGAGATCA TCGAGAGCCT CAAGAAGAAC CCTGTCACCG CTGTCCCCGT TGTCCTGAAA 
AGACTGAAGG CCAAGGAAGA GGAGTGGCGG GAGGCCCAGC AGGGCTTCAA CAAGATCTGG 
CGGGAGCAGT ATGAGAAGGC GTACCTCAAG TCCCTTGACC ACCAGGCTGT GAACTTCAAG 
CAGAACGACA CCAAGGCCCT GCGCTCCAAG AGCTTGCTCA ACGAGATCGA GAGCGTCTAC 
GACGAGCACC AGGAGCAGCA CTCGGAGGGC CGCAGTGCCC CCTCTAGCGA GCCGCACCTC 
ATCTTTGTGT ACGAGGACCG GCAGATCCTG GAGGACGCAG CAGCGCTCAT CAGCTACTAC 
GTGAAGCGGC AGCCGGCCAT CCAGAAGGAG GACCAGGGCA CCATCCACCA GCTGCTGCAC 
CAGTTCGTGC CCAGCCTCTT CTTCTCTCAG CAGCTGGACC TGGGCGCCTC CGAGGAGTCA 
GCTGATGAGG ACCGGGACAG CCCCCAGGGG CAGACCACAG ACCCCAGTGA GCGGAAGAAG 
CCGGCGCCAG GACCCCACAG TAGCCCCCCA GAGGAGAAGG GGGCCTTCGG GGATGCCCCG 
GCCACTGAGC AGCCACCCCT GCCGCCCCCA GCCCCGCACA AGCCCCTGGA CGATGTCTAC 
AGCCTATTTT TTGCCAACAA CAACTGGTAC TTCTTCCTGC GCCTGCACCA GACCCTGTGC 
TCCAGGCTGC TGAAGATCTA CCGCCAGGCG CAGAAGCAGC TTCTGGAGTA TCGGACCGAG 
AAGGAGCGGG AGAAGCTGCT GTGTGAGGGC CGCAGGGAGA AGGGCAGCGA CCCCGCCATG 
GAGCTGCGGC TGAAGCAGCC CAGTGAAGTG GAGCTGGAGG AGTACTACCC GGCCTTCCTG 
GACATGGTGC GGAGCCTGCT GGAGGGCAGC ATCGACCCCA CGCAGTACGA GGACACCCTA 
CGCGAGATGT TCACCATCCA TGCCTACGTG GGCTTCACCA TGGACAAGCT GGTGCAGAAC 
ATTGCGCGGC AGCTGCACCA CCTCGTGAGC GATGACGTCT GCCTGAAGGT GGTGGAGCTC 
TACCTGAACG AGAAGAAGCG GGGTGCCGCT GGTGGGAACC TGTCCTCCCG CTGCGTCCGC 
GCTGCTAGGG AGACCAGCTA CCAGTGGAAG GCTGAGCGCT GCATGGCCGA CGAGAACTGC 
TTCAAGGTGA TGTTCCTGCA GCGCAAAGGG CAGGTGATCA TGACCATCGA GCTCCTGGAC 
ACCGAGGAGG CCCAGACGGA GGACCCTGTG GAGGTCCAGC ACCTGGCTCG GTACGTGGAG 
CAGTATGTGG GGACCGAGGG CGCGTCCAGC TCGCCCACTG AGGGCTTCCT CCTGAAACCT 
GTGTTCCTGC AGAGGAACCT CAAGAAGTTC CGCCGCCGGT GGCAGAGCGA GCAGGCGCGG 
GCCCTGCGCG GTGAGGCCAG GAGCTCCTGG AAGCGGCTGG TGGGCGTGGA GAGCGCCTGC 
GACGTGGACT GCCGCTTCAA GCTCAGCACT CACAAGATGG TGTTCATCGT GAACTCCGAG 
GACTACATGT ACCGTCGCGG GACCCTCTGC CGGGCCAAGC AGGTGCAGCC CCTGGTCCTG 
CTCCGCCACC ACCAGCACTT TGAGGAGTGG CACAGCCGCT GGCTGGAGGA CAATGTGACG 
GTGGAGGCGG CTAGCCTGGT GCAGGACTGG CTGATGGGTG AGGAGGACGA GGACATGGTA 
CCCTGCAAGA CGCTGTGTGA GACAGTGCAC GTGCACGGCC TGCCCGTGAC CCGCTACCGC 
GTGCAGTACA GCCGCCGCCC GGCCTCGCCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001284524.1
CDS	35..3427
Translation	MAHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLTSQENSHNHGDGAEDFKQQVPYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKEVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCETVHVHGLPVTRYRVQYSRRPASP

Target ORF information:

RefSeq Version	NM_001297595.1
Organism	Homo sapiens(human)
Definition	Homo sapiens SIN3 transcription regulator family member B (SIN3B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001297595.1

ORF Insert Sequence:

ATGGCGCACG CTGGCGGTGG CAGCGGTGGC AGCGGTGCCG GCGGCCCCGC GGGCCGGGGG 
CTGAGCGGCG CCCGCTGGGG TCGCTCGGGC TCCGCAGGCC ACGAGAAGCT GCCGGTGCAC 
GTAGAAGACG CCCTCACCTA TCTGGACCAG GTGAAGATCC GCTTTGGCAG CGACCCTGCC 
ACCTACAACG GCTTCCTGGA GATCATGAAG GAGTTCAAAA GCCAGAGCAT CGATACTCCT 
GGAGTCATCA GACGTGTCTC GCAGCTCTTC CACGAGCACC CTGACCTCAT TGTTGGATTC 
AACGCTTTTC TTCCCCTCGG ATATAGAATA GACATTCCCA AGAATGGCAA GTTAAACATA 
CAGTCGCCTC TGACAAGCCA GGAGAATTCG CACAACCACG GGGACGGTGC AGAGGACTTC 
AAGCAGCAGG TGCCGTATAA AGAGGACAAA CCCCAGGTGC CCCTGGAGTC CGATTCCGTG 
GAATTCAACA ACGCCATCAG CTATGTGAAT AAGATTAAAA CCCGCTTCCT AGACCACCCA 
GAAATCTACA GGTCATTCCT GGAGATCCTG CACACGTACC AGAAGGAGCA GCTGAACACG 
AGGGGCCGGC CATTCCGAGG CATGTCTGAA GAGGAGGTGT TCACCGAGGT GGCCAACCTC 
TTCCGGGGCC AGGAGGACCT GCTCTCAGAG TTTGGACAGT TCCTGCCCGA AGCCAAGCGG 
TCTCTGTTCA CAGGAAACGG GCCGTGCGAG ATGCACAGCG TGCAGAAGAA CGAGCACGAC 
AAGACCCCGG AGCACAGCAG GAAGCGCTCC CGGCCCTCGC TCCTCCGCCC CGTGTCTGCA 
CCCGCCAAGA AAAAAATGAA ACTTCGTGGT ACCAAAGACC TGTCCATCGC TGCAGTGGGG 
AAGTACGGGA CTCTGCAGGA ATTTTCTTTC TTTGACAAGG TCCGCCGGGT GCTGAAGAGC 
CAGGAGGTGT ATGAAAACTT CCTCCGCTGC ATCGCACTCT TCAACCAGGA GCTGGTGTCT 
GGCTCTGAGC TCCTGCAGCT CGTCAGCCCA TTTCTGGGGA AATTTCCAGA ACTCTTTGCA 
CAGTTCAAGT CCTTCCTGGG GGTAAAAGAG CTGTCCTTCG CGCCACCCAT GAGCGACAGA 
TCCGGGGACG GGATAAGCCG GGAAATTGAT TATGCATCCT GCAAGCGCAT AGGATCCAGC 
TACCGGGCAC TCCCCAAAAC CTACCAGCAG CCCAAGTGCA GTGGGAGGAC AGCCATCTGC 
AAGGAGGTAC TGAACGACAC CTGGGTCTCC TTCCCTTCCT GGTCTGAGGA CTCCACGTTC 
GTCAGCTCCA AGAAGACACC GTACGAGGAG CAGCTTCACC GCTGTGAGGA CGAGCGCTTC 
GAGTTAGACG TTGTCCTGGA GACGAACCTG GCCACAATCC GTGTGTTGGA AAGTGTGCAG 
AAGAAGCTGT CTCGGATGGC GCCGGAAGAC CAGGAGAAGT TCCGGCTGGA CGACTCCCTG 
GGAGGCACGT CGGAGGTGAT CCAGCGCCGT GCCATTTATC GCATCTATGG CGACAAGGCC 
CCGGAGATCA TCGAGAGCCT CAAGAAGAAC CCTGTCACCG CTGTCCCCGT TGTCCTGAAA 
AGACTGAAGG CCAAGGAAGA GGAGTGGCGG GAGGCCCAGC AGGGCTTCAA CAAGATCTGG 
CGGGAGCAGT ATGAGAAGGC GTACCTCAAG TCCCTTGACC ACCAGGCTGT GAACTTCAAG 
CAGAACGACA CCAAGGCCCT GCGCTCCAAG AGCTTGCTCA ACGAGATCGA GAGCGTCTAC 
GACGAGCACC AGGAGCAGCA CTCGGAGGGC CGCAGTGCCC CCTCTAGCGA GCCGCACCTC 
ATCTTTGTGT ACGAGGACCG GCAGATCCTG GAGGACGCAG CAGCGCTCAT CAGCTACTAC 
GTGAAGCGGC AGCCGGCCAT CCAGAAGGAG GACCAGGGCA CCATCCACCA GCTGCTGCAC 
CAGTTCGTGC CCAGCCTCTT CTTCTCTCAG CAGCTGGACC TGGGCGCCTC CGAGGAGTCA 
GCTGATGAGG ACCGGGACAG CCCCCAGGGG CAGACCACAG ACCCCAGTGA GCGGAAGAAG 
CCGGCGCCAG GACCCCACAG TAGCCCCCCA GAGGAGAAGG GGGCCTTCGG GGATGCCCCG 
GCCACTGAGC AGCCACCCCT GCCGCCCCCA GCCCCGCACA AGCCCCTGGA CGATGTCTAC 
AGCCTATTTT TTGCCAACAA CAACTGGTAC TTCTTCCTGC GCCTGCACCA GACCCTGTGC 
TCCAGGCTGC TGAAGATCTA CCGCCAGGCG CAGAAGCAGC TTCTGGAGTA TCGGACCGAG 
AAGGAGCGGG AGAAGCTGCT GTGTGAGGGC CGCAGGGAGA AGGGCAGCGA CCCCGCCATG 
GAGCTGCGGC TGAAGCAGCC CAGTGAAGTG GAGCTGGAGG AGTACTACCC GGCCTTCCTG 
GACATGGTGC GGAGCCTGCT GGAGGGCAGC ATCGACCCCA CGCAGTACGA GGACACCCTA 
CGCGAGATGT TCACCATCCA TGCCTACGTG GGCTTCACCA TGGACAAGCT GGTGCAGAAC 
ATTGCGCGGC AGCTGCACCA CCTCGTGAGC GATGACGTCT GCCTGAAGGT GGTGGAGCTC 
TACCTGAACG AGAAGAAGCG GGGTGCCGCT GGTGGGAACC TGTCCTCCCG CTGCGTCCGC 
GCTGCTAGGG AGACCAGCTA CCAGTGGAAG GCTGAGCGCT GCATGGCCGA CGAGAACTGC 
TTCAAGGTGA TGTTCCTGCA GCGCAAAGGG CAGGTGATCA TGACCATCGA GCTCCTGGAC 
ACCGAGGAGG CCCAGACGGA GGACCCTGTG GAGGTCCAGC ACCTGGCTCG GTACGTGGAG 
CAGTATGTGG GGACCGAGGG CGCGTCCAGC TCGCCCACTG AGGGCTTCCT CCTGAAACCT 
GTGTTCCTGC AGAGGAACCT CAAGAAGTTC CGCCGCCGGT GGCAGAGCGA GCAGGCGCGG 
GCCCTGCGCG GTGAGGCCAG GAGCTCCTGG AAGCGGCTGG TGGGCGTGGA GAGCGCCTGC 
GACGTGGACT GCCGCTTCAA GCTCAGCACT CACAAGATGG TGTTCATCGT GAACTCCGAG 
GACTACATGT ACCGTCGCGG GACCCTCTGC CGGGCCAAGC AGGTGCAGCC CCTGGTCCTG 
CTCCGCCACC ACCAGCACTT TGAGGAGTGG CACAGCCGCT GGCTGGAGGA CAATGTGACG 
GTGGAGGCGG CTAGCCTGGT GCAGGACTGG CTGATGGGTG AGGAGGACGA GGACATGGTA 
CCCTGCAAGA CGCTGTGTGA GACAGTGCAC GTGCACGGCC TGCCCGTGAC CCGCTACCGC 
GTGCAGTACA GCCGCCGCCC GGCCTCGCCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SIN3B ( NM_015260.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_056075.1 Homo sapiens SIN3 transcription regulator family member B (SIN3B), transcript variant 1, mRNA.

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CloneID	OHu28835
Clone ID Related Accession (Same CDS sequence)	NM_015260.3 , NM_015260.4
Accession Version	NM_015260.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3489bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	paired amphipathic helix protein Sin3b isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HY055983.1 and AY706204.1. On Jul 4, 2014 this sequence version replaced NM_015260.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY706204.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGCACG CTGGCGGTGG CAGCGGTGGC AGCGGTGCCG GCGGCCCCGC GGGCCGGGGG 
CTGAGCGGCG CCCGCTGGGG TCGCTCGGGC TCCGCAGGCC ACGAGAAGCT GCCGGTGCAC 
GTAGAAGACG CCCTCACCTA TCTGGACCAG GTGAAGATCC GCTTTGGCAG CGACCCTGCC 
ACCTACAACG GCTTCCTGGA GATCATGAAG GAGTTCAAAA GCCAGAGCAT CGATACTCCT 
GGAGTCATCA GACGTGTCTC GCAGCTCTTC CACGAGCACC CTGACCTCAT TGTTGGATTC 
AACGCTTTTC TTCCCCTCGG ATATAGAATA GACATTCCCA AGAATGGCAA GTTAAACATA 
CAGTCGCCTC TGACAAGCCA GGAGAATTCG CACAACCACG GGGACGGTGC AGAGGACTTC 
AAGCAGCAGG TGCCGTATAA AGAGGACAAA CCCCAGGTGC CCCTGGAGTC CGATTCCGTG 
GAATTCAACA ACGCCATCAG CTATGTGAAT AAGATTAAAA CCCGCTTCCT AGACCACCCA 
GAAATCTACA GGTCATTCCT GGAGATCCTG CACACGTACC AGAAGGAGCA GCTGAACACG 
AGGGGCCGGC CATTCCGAGG CATGTCTGAA GAGGAGGTGT TCACCGAGGT GGCCAACCTC 
TTCCGGGGCC AGGAGGACCT GCTCTCAGAG TTTGGACAGT TCCTGCCCGA AGCCAAGCGG 
TCTCTGTTCA CAGGAAACGG GCCGTGCGAG ATGCACAGCG TGCAGAAGAA CGAGCACGAC 
AAGACCCCGG AGCACAGCAG GAAGCGCTCC CGGCCCTCGC TCCTCCGCCC CGTGTCTGCA 
CCCGCCAAGA AAAAAATGAA ACTTCGTGGT ACCAAAGACC TGTCCATCGC TGCAGTGGGG 
AAGTACGGGA CTCTGCAGGA ATTTTCTTTC TTTGACAAGG TCCGCCGGGT GCTGAAGAGC 
CAGGAGGTGT ATGAAAACTT CCTCCGCTGC ATCGCACTCT TCAACCAGGA GCTGGTGTCT 
GGCTCTGAGC TCCTGCAGCT CGTCAGCCCA TTTCTGGGGA AATTTCCAGA ACTCTTTGCA 
CAGTTCAAGT CCTTCCTGGG GGTAAAAGAG CTGTCCTTCG CGCCACCCAT GAGCGACAGA 
TCCGGGGACG GGATAAGCCG GGAAATTGAT TATGCATCCT GCAAGCGCAT AGGATCCAGC 
TACCGGGCAC TCCCCAAAAC CTACCAGCAG CCCAAGTGCA GTGGGAGGAC AGCCATCTGC 
AAGGAGCTTG ACCATTGGAC ACTTCTCCAG GGTTCGTGGA CAGACGATTA CTGCATGTCC 
AAGTTCAAGA ATACCTGCTG GATTCCAGGA TATAGTGCAG GGGTACTGAA CGACACCTGG 
GTCTCCTTCC CTTCCTGGTC TGAGGACTCC ACGTTCGTCA GCTCCAAGAA GACACCGTAC 
GAGGAGCAGC TTCACCGCTG TGAGGACGAG CGCTTCGAGT TAGACGTTGT CCTGGAGACG 
AACCTGGCCA CAATCCGTGT GTTGGAAAGT GTGCAGAAGA AGCTGTCTCG GATGGCGCCG 
GAAGACCAGG AGAAGTTCCG GCTGGACGAC TCCCTGGGAG GCACGTCGGA GGTGATCCAG 
CGCCGTGCCA TTTATCGCAT CTATGGCGAC AAGGCCCCGG AGATCATCGA GAGCCTCAAG 
AAGAACCCTG TCACCGCTGT CCCCGTTGTC CTGAAAAGAC TGAAGGCCAA GGAAGAGGAG 
TGGCGGGAGG CCCAGCAGGG CTTCAACAAG ATCTGGCGGG AGCAGTATGA GAAGGCGTAC 
CTCAAGTCCC TTGACCACCA GGCTGTGAAC TTCAAGCAGA ACGACACCAA GGCCCTGCGC 
TCCAAGAGCT TGCTCAACGA GATCGAGAGC GTCTACGACG AGCACCAGGA GCAGCACTCG 
GAGGGCCGCA GTGCCCCCTC TAGCGAGCCG CACCTCATCT TTGTGTACGA GGACCGGCAG 
ATCCTGGAGG ACGCAGCAGC GCTCATCAGC TACTACGTGA AGCGGCAGCC GGCCATCCAG 
AAGGAGGACC AGGGCACCAT CCACCAGCTG CTGCACCAGT TCGTGCCCAG CCTCTTCTTC 
TCTCAGCAGC TGGACCTGGG CGCCTCCGAG GAGTCAGCTG ATGAGGACCG GGACAGCCCC 
CAGGGGCAGA CCACAGACCC CAGTGAGCGG AAGAAGCCGG CGCCAGGACC CCACAGTAGC 
CCCCCAGAGG AGAAGGGGGC CTTCGGGGAT GCCCCGGCCA CTGAGCAGCC ACCCCTGCCG 
CCCCCAGCCC CGCACAAGCC CCTGGACGAT GTCTACAGCC TATTTTTTGC CAACAACAAC 
TGGTACTTCT TCCTGCGCCT GCACCAGACC CTGTGCTCCA GGCTGCTGAA GATCTACCGC 
CAGGCGCAGA AGCAGCTTCT GGAGTATCGG ACCGAGAAGG AGCGGGAGAA GCTGCTGTGT 
GAGGGCCGCA GGGAGAAGGG CAGCGACCCC GCCATGGAGC TGCGGCTGAA GCAGCCCAGT 
GAAGTGGAGC TGGAGGAGTA CTACCCGGCC TTCCTGGACA TGGTGCGGAG CCTGCTGGAG 
GGCAGCATCG ACCCCACGCA GTACGAGGAC ACCCTACGCG AGATGTTCAC CATCCATGCC 
TACGTGGGCT TCACCATGGA CAAGCTGGTG CAGAACATTG CGCGGCAGCT GCACCACCTC 
GTGAGCGATG ACGTCTGCCT GAAGGTGGTG GAGCTCTACC TGAACGAGAA GAAGCGGGGT 
GCCGCTGGTG GGAACCTGTC CTCCCGCTGC GTCCGCGCTG CTAGGGAGAC CAGCTACCAG 
TGGAAGGCTG AGCGCTGCAT GGCCGACGAG AACTGCTTCA AGGTGATGTT CCTGCAGCGC 
AAAGGGCAGG TGATCATGAC CATCGAGCTC CTGGACACCG AGGAGGCCCA GACGGAGGAC 
CCTGTGGAGG TCCAGCACCT GGCTCGGTAC GTGGAGCAGT ATGTGGGGAC CGAGGGCGCG 
TCCAGCTCGC CCACTGAGGG CTTCCTCCTG AAACCTGTGT TCCTGCAGAG GAACCTCAAG 
AAGTTCCGCC GCCGGTGGCA GAGCGAGCAG GCGCGGGCCC TGCGCGGTGA GGCCAGGAGC 
TCCTGGAAGC GGCTGGTGGG CGTGGAGAGC GCCTGCGACG TGGACTGCCG CTTCAAGCTC 
AGCACTCACA AGATGGTGTT CATCGTGAAC TCCGAGGACT ACATGTACCG TCGCGGGACC 
CTCTGCCGGG CCAAGCAGGT GCAGCCCCTG GTCCTGCTCC GCCACCACCA GCACTTTGAG 
GAGTGGCACA GCCGCTGGCT GGAGGACAAT GTGACGGTGG AGGCGGCTAG CCTGGTGCAG 
GACTGGCTGA TGGGTGAGGA GGACGAGGAC ATGGTACCCT GCAAGACGCT GTGTGAGACA 
GTGCACGTGC ACGGCCTGCC CGTGACCCGC TACCGCGTGC AGTACAGCCG CCGCCCGGCC 
TCGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056075.1
CDS	35..3523
Translation	MAHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLTSQENSHNHGDGAEDFKQQVPYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKELDHWTLLQGSWTDDYCMSKFKNTCWIPGYSAGVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCETVHVHGLPVTRYRVQYSRRPASP

Target ORF information:

RefSeq Version	NM_015260.3
Organism	Homo sapiens(human)
Definition	Homo sapiens SIN3 transcription regulator family member B (SIN3B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015260.3

ORF Insert Sequence:

ATGGCGCACG CTGGCGGTGG CAGCGGTGGC AGCGGTGCCG GCGGCCCCGC GGGCCGGGGG 
CTGAGCGGCG CCCGCTGGGG TCGCTCGGGC TCCGCAGGCC ACGAGAAGCT GCCGGTGCAC 
GTAGAAGACG CCCTCACCTA TCTGGACCAG GTGAAGATCC GCTTTGGCAG CGACCCTGCC 
ACCTACAACG GCTTCCTGGA GATCATGAAG GAGTTCAAAA GCCAGAGCAT CGATACTCCT 
GGAGTCATCA GACGTGTCTC GCAGCTCTTC CACGAGCACC CTGACCTCAT TGTTGGATTC 
AACGCTTTTC TTCCCCTCGG ATATAGAATA GACATTCCCA AGAATGGCAA GTTAAACATA 
CAGTCGCCTC TGACAAGCCA GGAGAATTCG CACAACCACG GGGACGGTGC AGAGGACTTC 
AAGCAGCAGG TGCCGTATAA AGAGGACAAA CCCCAGGTGC CCCTGGAGTC CGATTCCGTG 
GAATTCAACA ACGCCATCAG CTATGTGAAT AAGATTAAAA CCCGCTTCCT AGACCACCCA 
GAAATCTACA GGTCATTCCT GGAGATCCTG CACACGTACC AGAAGGAGCA GCTGAACACG 
AGGGGCCGGC CATTCCGAGG CATGTCTGAA GAGGAGGTGT TCACCGAGGT GGCCAACCTC 
TTCCGGGGCC AGGAGGACCT GCTCTCAGAG TTTGGACAGT TCCTGCCCGA AGCCAAGCGG 
TCTCTGTTCA CAGGAAACGG GCCGTGCGAG ATGCACAGCG TGCAGAAGAA CGAGCACGAC 
AAGACCCCGG AGCACAGCAG GAAGCGCTCC CGGCCCTCGC TCCTCCGCCC CGTGTCTGCA 
CCCGCCAAGA AAAAAATGAA ACTTCGTGGT ACCAAAGACC TGTCCATCGC TGCAGTGGGG 
AAGTACGGGA CTCTGCAGGA ATTTTCTTTC TTTGACAAGG TCCGCCGGGT GCTGAAGAGC 
CAGGAGGTGT ATGAAAACTT CCTCCGCTGC ATCGCACTCT TCAACCAGGA GCTGGTGTCT 
GGCTCTGAGC TCCTGCAGCT CGTCAGCCCA TTTCTGGGGA AATTTCCAGA ACTCTTTGCA 
CAGTTCAAGT CCTTCCTGGG GGTAAAAGAG CTGTCCTTCG CGCCACCCAT GAGCGACAGA 
TCCGGGGACG GGATAAGCCG GGAAATTGAT TATGCATCCT GCAAGCGCAT AGGATCCAGC 
TACCGGGCAC TCCCCAAAAC CTACCAGCAG CCCAAGTGCA GTGGGAGGAC AGCCATCTGC 
AAGGAGCTTG ACCATTGGAC ACTTCTCCAG GGTTCGTGGA CAGACGATTA CTGCATGTCC 
AAGTTCAAGA ATACCTGCTG GATTCCAGGA TATAGTGCAG GGGTACTGAA CGACACCTGG 
GTCTCCTTCC CTTCCTGGTC TGAGGACTCC ACGTTCGTCA GCTCCAAGAA GACACCGTAC 
GAGGAGCAGC TTCACCGCTG TGAGGACGAG CGCTTCGAGT TAGACGTTGT CCTGGAGACG 
AACCTGGCCA CAATCCGTGT GTTGGAAAGT GTGCAGAAGA AGCTGTCTCG GATGGCGCCG 
GAAGACCAGG AGAAGTTCCG GCTGGACGAC TCCCTGGGAG GCACGTCGGA GGTGATCCAG 
CGCCGTGCCA TTTATCGCAT CTATGGCGAC AAGGCCCCGG AGATCATCGA GAGCCTCAAG 
AAGAACCCTG TCACCGCTGT CCCCGTTGTC CTGAAAAGAC TGAAGGCCAA GGAAGAGGAG 
TGGCGGGAGG CCCAGCAGGG CTTCAACAAG ATCTGGCGGG AGCAGTATGA GAAGGCGTAC 
CTCAAGTCCC TTGACCACCA GGCTGTGAAC TTCAAGCAGA ACGACACCAA GGCCCTGCGC 
TCCAAGAGCT TGCTCAACGA GATCGAGAGC GTCTACGACG AGCACCAGGA GCAGCACTCG 
GAGGGCCGCA GTGCCCCCTC TAGCGAGCCG CACCTCATCT TTGTGTACGA GGACCGGCAG 
ATCCTGGAGG ACGCAGCAGC GCTCATCAGC TACTACGTGA AGCGGCAGCC GGCCATCCAG 
AAGGAGGACC AGGGCACCAT CCACCAGCTG CTGCACCAGT TCGTGCCCAG CCTCTTCTTC 
TCTCAGCAGC TGGACCTGGG CGCCTCCGAG GAGTCAGCTG ATGAGGACCG GGACAGCCCC 
CAGGGGCAGA CCACAGACCC CAGTGAGCGG AAGAAGCCGG CGCCAGGACC CCACAGTAGC 
CCCCCAGAGG AGAAGGGGGC CTTCGGGGAT GCCCCGGCCA CTGAGCAGCC ACCCCTGCCG 
CCCCCAGCCC CGCACAAGCC CCTGGACGAT GTCTACAGCC TATTTTTTGC CAACAACAAC 
TGGTACTTCT TCCTGCGCCT GCACCAGACC CTGTGCTCCA GGCTGCTGAA GATCTACCGC 
CAGGCGCAGA AGCAGCTTCT GGAGTATCGG ACCGAGAAGG AGCGGGAGAA GCTGCTGTGT 
GAGGGCCGCA GGGAGAAGGG CAGCGACCCC GCCATGGAGC TGCGGCTGAA GCAGCCCAGT 
GAAGTGGAGC TGGAGGAGTA CTACCCGGCC TTCCTGGACA TGGTGCGGAG CCTGCTGGAG 
GGCAGCATCG ACCCCACGCA GTACGAGGAC ACCCTACGCG AGATGTTCAC CATCCATGCC 
TACGTGGGCT TCACCATGGA CAAGCTGGTG CAGAACATTG CGCGGCAGCT GCACCACCTC 
GTGAGCGATG ACGTCTGCCT GAAGGTGGTG GAGCTCTACC TGAACGAGAA GAAGCGGGGT 
GCCGCTGGTG GGAACCTGTC CTCCCGCTGC GTCCGCGCTG CTAGGGAGAC CAGCTACCAG 
TGGAAGGCTG AGCGCTGCAT GGCCGACGAG AACTGCTTCA AGGTGATGTT CCTGCAGCGC 
AAAGGGCAGG TGATCATGAC CATCGAGCTC CTGGACACCG AGGAGGCCCA GACGGAGGAC 
CCTGTGGAGG TCCAGCACCT GGCTCGGTAC GTGGAGCAGT ATGTGGGGAC CGAGGGCGCG 
TCCAGCTCGC CCACTGAGGG CTTCCTCCTG AAACCTGTGT TCCTGCAGAG GAACCTCAAG 
AAGTTCCGCC GCCGGTGGCA GAGCGAGCAG GCGCGGGCCC TGCGCGGTGA GGCCAGGAGC 
TCCTGGAAGC GGCTGGTGGG CGTGGAGAGC GCCTGCGACG TGGACTGCCG CTTCAAGCTC 
AGCACTCACA AGATGGTGTT CATCGTGAAC TCCGAGGACT ACATGTACCG TCGCGGGACC 
CTCTGCCGGG CCAAGCAGGT GCAGCCCCTG GTCCTGCTCC GCCACCACCA GCACTTTGAG 
GAGTGGCACA GCCGCTGGCT GGAGGACAAT GTGACGGTGG AGGCGGCTAG CCTGGTGCAG 
GACTGGCTGA TGGGTGAGGA GGACGAGGAC ATGGTACCCT GCAAGACGCT GTGTGAGACA 
GTGCACGTGC ACGGCCTGCC CGTGACCCGC TACCGCGTGC AGTACAGCCG CCGCCCGGCC 
TCGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SIN3B ( NM_015260.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_056075.1 Homo sapiens SIN3 transcription regulator family member B (SIN3B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu28835
Clone ID Related Accession (Same CDS sequence)	NM_015260.3 , NM_015260.4
Accession Version	NM_015260.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3489bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-18
Organism	Homo sapiens(human)
Product	paired amphipathic helix protein Sin3b isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HY055983.1 and AY706204.1. On Jun 2, 2019 this sequence version replaced NM_015260.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY706204.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGCACG CTGGCGGTGG CAGCGGTGGC AGCGGTGCCG GCGGCCCCGC GGGCCGGGGG 
CTGAGCGGCG CCCGCTGGGG TCGCTCGGGC TCCGCAGGCC ACGAGAAGCT GCCGGTGCAC 
GTAGAAGACG CCCTCACCTA TCTGGACCAG GTGAAGATCC GCTTTGGCAG CGACCCTGCC 
ACCTACAACG GCTTCCTGGA GATCATGAAG GAGTTCAAAA GCCAGAGCAT CGATACTCCT 
GGAGTCATCA GACGTGTCTC GCAGCTCTTC CACGAGCACC CTGACCTCAT TGTTGGATTC 
AACGCTTTTC TTCCCCTCGG ATATAGAATA GACATTCCCA AGAATGGCAA GTTAAACATA 
CAGTCGCCTC TGACAAGCCA GGAGAATTCG CACAACCACG GGGACGGTGC AGAGGACTTC 
AAGCAGCAGG TGCCGTATAA AGAGGACAAA CCCCAGGTGC CCCTGGAGTC CGATTCCGTG 
GAATTCAACA ACGCCATCAG CTATGTGAAT AAGATTAAAA CCCGCTTCCT AGACCACCCA 
GAAATCTACA GGTCATTCCT GGAGATCCTG CACACGTACC AGAAGGAGCA GCTGAACACG 
AGGGGCCGGC CATTCCGAGG CATGTCTGAA GAGGAGGTGT TCACCGAGGT GGCCAACCTC 
TTCCGGGGCC AGGAGGACCT GCTCTCAGAG TTTGGACAGT TCCTGCCCGA AGCCAAGCGG 
TCTCTGTTCA CAGGAAACGG GCCGTGCGAG ATGCACAGCG TGCAGAAGAA CGAGCACGAC 
AAGACCCCGG AGCACAGCAG GAAGCGCTCC CGGCCCTCGC TCCTCCGCCC CGTGTCTGCA 
CCCGCCAAGA AAAAAATGAA ACTTCGTGGT ACCAAAGACC TGTCCATCGC TGCAGTGGGG 
AAGTACGGGA CTCTGCAGGA ATTTTCTTTC TTTGACAAGG TCCGCCGGGT GCTGAAGAGC 
CAGGAGGTGT ATGAAAACTT CCTCCGCTGC ATCGCACTCT TCAACCAGGA GCTGGTGTCT 
GGCTCTGAGC TCCTGCAGCT CGTCAGCCCA TTTCTGGGGA AATTTCCAGA ACTCTTTGCA 
CAGTTCAAGT CCTTCCTGGG GGTAAAAGAG CTGTCCTTCG CGCCACCCAT GAGCGACAGA 
TCCGGGGACG GGATAAGCCG GGAAATTGAT TATGCATCCT GCAAGCGCAT AGGATCCAGC 
TACCGGGCAC TCCCCAAAAC CTACCAGCAG CCCAAGTGCA GTGGGAGGAC AGCCATCTGC 
AAGGAGCTTG ACCATTGGAC ACTTCTCCAG GGTTCGTGGA CAGACGATTA CTGCATGTCC 
AAGTTCAAGA ATACCTGCTG GATTCCAGGA TATAGTGCAG GGGTACTGAA CGACACCTGG 
GTCTCCTTCC CTTCCTGGTC TGAGGACTCC ACGTTCGTCA GCTCCAAGAA GACACCGTAC 
GAGGAGCAGC TTCACCGCTG TGAGGACGAG CGCTTCGAGT TAGACGTTGT CCTGGAGACG 
AACCTGGCCA CAATCCGTGT GTTGGAAAGT GTGCAGAAGA AGCTGTCTCG GATGGCGCCG 
GAAGACCAGG AGAAGTTCCG GCTGGACGAC TCCCTGGGAG GCACGTCGGA GGTGATCCAG 
CGCCGTGCCA TTTATCGCAT CTATGGCGAC AAGGCCCCGG AGATCATCGA GAGCCTCAAG 
AAGAACCCTG TCACCGCTGT CCCCGTTGTC CTGAAAAGAC TGAAGGCCAA GGAAGAGGAG 
TGGCGGGAGG CCCAGCAGGG CTTCAACAAG ATCTGGCGGG AGCAGTATGA GAAGGCGTAC 
CTCAAGTCCC TTGACCACCA GGCTGTGAAC TTCAAGCAGA ACGACACCAA GGCCCTGCGC 
TCCAAGAGCT TGCTCAACGA GATCGAGAGC GTCTACGACG AGCACCAGGA GCAGCACTCG 
GAGGGCCGCA GTGCCCCCTC TAGCGAGCCG CACCTCATCT TTGTGTACGA GGACCGGCAG 
ATCCTGGAGG ACGCAGCAGC GCTCATCAGC TACTACGTGA AGCGGCAGCC GGCCATCCAG 
AAGGAGGACC AGGGCACCAT CCACCAGCTG CTGCACCAGT TCGTGCCCAG CCTCTTCTTC 
TCTCAGCAGC TGGACCTGGG CGCCTCCGAG GAGTCAGCTG ATGAGGACCG GGACAGCCCC 
CAGGGGCAGA CCACAGACCC CAGTGAGCGG AAGAAGCCGG CGCCAGGACC CCACAGTAGC 
CCCCCAGAGG AGAAGGGGGC CTTCGGGGAT GCCCCGGCCA CTGAGCAGCC ACCCCTGCCG 
CCCCCAGCCC CGCACAAGCC CCTGGACGAT GTCTACAGCC TATTTTTTGC CAACAACAAC 
TGGTACTTCT TCCTGCGCCT GCACCAGACC CTGTGCTCCA GGCTGCTGAA GATCTACCGC 
CAGGCGCAGA AGCAGCTTCT GGAGTATCGG ACCGAGAAGG AGCGGGAGAA GCTGCTGTGT 
GAGGGCCGCA GGGAGAAGGG CAGCGACCCC GCCATGGAGC TGCGGCTGAA GCAGCCCAGT 
GAAGTGGAGC TGGAGGAGTA CTACCCGGCC TTCCTGGACA TGGTGCGGAG CCTGCTGGAG 
GGCAGCATCG ACCCCACGCA GTACGAGGAC ACCCTACGCG AGATGTTCAC CATCCATGCC 
TACGTGGGCT TCACCATGGA CAAGCTGGTG CAGAACATTG CGCGGCAGCT GCACCACCTC 
GTGAGCGATG ACGTCTGCCT GAAGGTGGTG GAGCTCTACC TGAACGAGAA GAAGCGGGGT 
GCCGCTGGTG GGAACCTGTC CTCCCGCTGC GTCCGCGCTG CTAGGGAGAC CAGCTACCAG 
TGGAAGGCTG AGCGCTGCAT GGCCGACGAG AACTGCTTCA AGGTGATGTT CCTGCAGCGC 
AAAGGGCAGG TGATCATGAC CATCGAGCTC CTGGACACCG AGGAGGCCCA GACGGAGGAC 
CCTGTGGAGG TCCAGCACCT GGCTCGGTAC GTGGAGCAGT ATGTGGGGAC CGAGGGCGCG 
TCCAGCTCGC CCACTGAGGG CTTCCTCCTG AAACCTGTGT TCCTGCAGAG GAACCTCAAG 
AAGTTCCGCC GCCGGTGGCA GAGCGAGCAG GCGCGGGCCC TGCGCGGTGA GGCCAGGAGC 
TCCTGGAAGC GGCTGGTGGG CGTGGAGAGC GCCTGCGACG TGGACTGCCG CTTCAAGCTC 
AGCACTCACA AGATGGTGTT CATCGTGAAC TCCGAGGACT ACATGTACCG TCGCGGGACC 
CTCTGCCGGG CCAAGCAGGT GCAGCCCCTG GTCCTGCTCC GCCACCACCA GCACTTTGAG 
GAGTGGCACA GCCGCTGGCT GGAGGACAAT GTGACGGTGG AGGCGGCTAG CCTGGTGCAG 
GACTGGCTGA TGGGTGAGGA GGACGAGGAC ATGGTACCCT GCAAGACGCT GTGTGAGACA 
GTGCACGTGC ACGGCCTGCC CGTGACCCGC TACCGCGTGC AGTACAGCCG CCGCCCGGCC 
TCGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056075.1
CDS	24..3512
Translation	MAHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLTSQENSHNHGDGAEDFKQQVPYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKELDHWTLLQGSWTDDYCMSKFKNTCWIPGYSAGVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCETVHVHGLPVTRYRVQYSRRPASP

Target ORF information:

RefSeq Version	NM_015260.4
Organism	Homo sapiens(human)
Definition	Homo sapiens SIN3 transcription regulator family member B (SIN3B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015260.4

ORF Insert Sequence:

ATGGCGCACG CTGGCGGTGG CAGCGGTGGC AGCGGTGCCG GCGGCCCCGC GGGCCGGGGG 
CTGAGCGGCG CCCGCTGGGG TCGCTCGGGC TCCGCAGGCC ACGAGAAGCT GCCGGTGCAC 
GTAGAAGACG CCCTCACCTA TCTGGACCAG GTGAAGATCC GCTTTGGCAG CGACCCTGCC 
ACCTACAACG GCTTCCTGGA GATCATGAAG GAGTTCAAAA GCCAGAGCAT CGATACTCCT 
GGAGTCATCA GACGTGTCTC GCAGCTCTTC CACGAGCACC CTGACCTCAT TGTTGGATTC 
AACGCTTTTC TTCCCCTCGG ATATAGAATA GACATTCCCA AGAATGGCAA GTTAAACATA 
CAGTCGCCTC TGACAAGCCA GGAGAATTCG CACAACCACG GGGACGGTGC AGAGGACTTC 
AAGCAGCAGG TGCCGTATAA AGAGGACAAA CCCCAGGTGC CCCTGGAGTC CGATTCCGTG 
GAATTCAACA ACGCCATCAG CTATGTGAAT AAGATTAAAA CCCGCTTCCT AGACCACCCA 
GAAATCTACA GGTCATTCCT GGAGATCCTG CACACGTACC AGAAGGAGCA GCTGAACACG 
AGGGGCCGGC CATTCCGAGG CATGTCTGAA GAGGAGGTGT TCACCGAGGT GGCCAACCTC 
TTCCGGGGCC AGGAGGACCT GCTCTCAGAG TTTGGACAGT TCCTGCCCGA AGCCAAGCGG 
TCTCTGTTCA CAGGAAACGG GCCGTGCGAG ATGCACAGCG TGCAGAAGAA CGAGCACGAC 
AAGACCCCGG AGCACAGCAG GAAGCGCTCC CGGCCCTCGC TCCTCCGCCC CGTGTCTGCA 
CCCGCCAAGA AAAAAATGAA ACTTCGTGGT ACCAAAGACC TGTCCATCGC TGCAGTGGGG 
AAGTACGGGA CTCTGCAGGA ATTTTCTTTC TTTGACAAGG TCCGCCGGGT GCTGAAGAGC 
CAGGAGGTGT ATGAAAACTT CCTCCGCTGC ATCGCACTCT TCAACCAGGA GCTGGTGTCT 
GGCTCTGAGC TCCTGCAGCT CGTCAGCCCA TTTCTGGGGA AATTTCCAGA ACTCTTTGCA 
CAGTTCAAGT CCTTCCTGGG GGTAAAAGAG CTGTCCTTCG CGCCACCCAT GAGCGACAGA 
TCCGGGGACG GGATAAGCCG GGAAATTGAT TATGCATCCT GCAAGCGCAT AGGATCCAGC 
TACCGGGCAC TCCCCAAAAC CTACCAGCAG CCCAAGTGCA GTGGGAGGAC AGCCATCTGC 
AAGGAGCTTG ACCATTGGAC ACTTCTCCAG GGTTCGTGGA CAGACGATTA CTGCATGTCC 
AAGTTCAAGA ATACCTGCTG GATTCCAGGA TATAGTGCAG GGGTACTGAA CGACACCTGG 
GTCTCCTTCC CTTCCTGGTC TGAGGACTCC ACGTTCGTCA GCTCCAAGAA GACACCGTAC 
GAGGAGCAGC TTCACCGCTG TGAGGACGAG CGCTTCGAGT TAGACGTTGT CCTGGAGACG 
AACCTGGCCA CAATCCGTGT GTTGGAAAGT GTGCAGAAGA AGCTGTCTCG GATGGCGCCG 
GAAGACCAGG AGAAGTTCCG GCTGGACGAC TCCCTGGGAG GCACGTCGGA GGTGATCCAG 
CGCCGTGCCA TTTATCGCAT CTATGGCGAC AAGGCCCCGG AGATCATCGA GAGCCTCAAG 
AAGAACCCTG TCACCGCTGT CCCCGTTGTC CTGAAAAGAC TGAAGGCCAA GGAAGAGGAG 
TGGCGGGAGG CCCAGCAGGG CTTCAACAAG ATCTGGCGGG AGCAGTATGA GAAGGCGTAC 
CTCAAGTCCC TTGACCACCA GGCTGTGAAC TTCAAGCAGA ACGACACCAA GGCCCTGCGC 
TCCAAGAGCT TGCTCAACGA GATCGAGAGC GTCTACGACG AGCACCAGGA GCAGCACTCG 
GAGGGCCGCA GTGCCCCCTC TAGCGAGCCG CACCTCATCT TTGTGTACGA GGACCGGCAG 
ATCCTGGAGG ACGCAGCAGC GCTCATCAGC TACTACGTGA AGCGGCAGCC GGCCATCCAG 
AAGGAGGACC AGGGCACCAT CCACCAGCTG CTGCACCAGT TCGTGCCCAG CCTCTTCTTC 
TCTCAGCAGC TGGACCTGGG CGCCTCCGAG GAGTCAGCTG ATGAGGACCG GGACAGCCCC 
CAGGGGCAGA CCACAGACCC CAGTGAGCGG AAGAAGCCGG CGCCAGGACC CCACAGTAGC 
CCCCCAGAGG AGAAGGGGGC CTTCGGGGAT GCCCCGGCCA CTGAGCAGCC ACCCCTGCCG 
CCCCCAGCCC CGCACAAGCC CCTGGACGAT GTCTACAGCC TATTTTTTGC CAACAACAAC 
TGGTACTTCT TCCTGCGCCT GCACCAGACC CTGTGCTCCA GGCTGCTGAA GATCTACCGC 
CAGGCGCAGA AGCAGCTTCT GGAGTATCGG ACCGAGAAGG AGCGGGAGAA GCTGCTGTGT 
GAGGGCCGCA GGGAGAAGGG CAGCGACCCC GCCATGGAGC TGCGGCTGAA GCAGCCCAGT 
GAAGTGGAGC TGGAGGAGTA CTACCCGGCC TTCCTGGACA TGGTGCGGAG CCTGCTGGAG 
GGCAGCATCG ACCCCACGCA GTACGAGGAC ACCCTACGCG AGATGTTCAC CATCCATGCC 
TACGTGGGCT TCACCATGGA CAAGCTGGTG CAGAACATTG CGCGGCAGCT GCACCACCTC 
GTGAGCGATG ACGTCTGCCT GAAGGTGGTG GAGCTCTACC TGAACGAGAA GAAGCGGGGT 
GCCGCTGGTG GGAACCTGTC CTCCCGCTGC GTCCGCGCTG CTAGGGAGAC CAGCTACCAG 
TGGAAGGCTG AGCGCTGCAT GGCCGACGAG AACTGCTTCA AGGTGATGTT CCTGCAGCGC 
AAAGGGCAGG TGATCATGAC CATCGAGCTC CTGGACACCG AGGAGGCCCA GACGGAGGAC 
CCTGTGGAGG TCCAGCACCT GGCTCGGTAC GTGGAGCAGT ATGTGGGGAC CGAGGGCGCG 
TCCAGCTCGC CCACTGAGGG CTTCCTCCTG AAACCTGTGT TCCTGCAGAG GAACCTCAAG 
AAGTTCCGCC GCCGGTGGCA GAGCGAGCAG GCGCGGGCCC TGCGCGGTGA GGCCAGGAGC 
TCCTGGAAGC GGCTGGTGGG CGTGGAGAGC GCCTGCGACG TGGACTGCCG CTTCAAGCTC 
AGCACTCACA AGATGGTGTT CATCGTGAAC TCCGAGGACT ACATGTACCG TCGCGGGACC 
CTCTGCCGGG CCAAGCAGGT GCAGCCCCTG GTCCTGCTCC GCCACCACCA GCACTTTGAG 
GAGTGGCACA GCCGCTGGCT GGAGGACAAT GTGACGGTGG AGGCGGCTAG CCTGGTGCAG 
GACTGGCTGA TGGGTGAGGA GGACGAGGAC ATGGTACCCT GCAAGACGCT GTGTGAGACA 
GTGCACGTGC ACGGCCTGCC CGTGACCCGC TACCGCGTGC AGTACAGCCG CCGCCCGGCC 
TCGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Chromatin-Associated Protein SIN3B Prevents Prostate Cancer Progression by Inducing Senescence.
Cancer research77(19)5339-5348(2017 Oct)
Bainor AJ,Deng FM,Wang Y,Lee P,Cantor DJ,Logan SK,David G

SIN3A and SIN3B differentially regulate breast cancer metastasis.
Oncotarget7(48)78713-78725(2016 Nov)
Lewis MJ,Liu J,Libby EF,Lee M,Crawford NP,Hurst DR

Stress-mediated Sin3B activation leads to negative regulation of subset of p53 target genes.
Bioscience reports35(4)(2015 Jun)
Kadamb R,Mittal S,Bansal N,Saluja D

pH might play a role in regulating the function of paired amphipathic helices domains of human Sin3B by altering structure and thermodynamic stability.
Biochemistry. Biokhimiia80(4)424-32(2015 Apr)
Hasan T,Ali M,Saluja D,Singh LR

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SIN3B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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