CSTF2T cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CSTF2T
Entrez Gene ID	23283
Full Name	cleavage stimulation factor subunit 2 tau variant
Synonyms	CstF-64T
General protein information	Preferred Names cleavage stimulation factor subunit 2 tau variant Names cleavage stimulation factor subunit 2 tau variant CF-1 64 kDa subunit tau CSTF 64 kDa subunit tau cleavage stimulation factor 64 kDa subunit tau cleavage stimulation factor subunit 2, tau cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau cleavage stimulation factor, 3' pre-RNA, subunit 2, tau tauCstF-64
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10q21.1
Disorder MIM:	611968

mRNA and Protein(s)

mRNA	Protein	Name
NM_015235.2	NP_056050.1	cleavage stimulation factor subunit 2 tau variant
NM_015235.3	NP_056050.1	cleavage stimulation factor subunit 2 tau variant

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	CSTF2T	XP_005636710.1
Rattus norvegicus (Norway rat)	Cstf2t	NP_001101056.1
Bos taurus (cattle)	CSTF2T	NP_001229511.1
Mus musculus (house mouse)	Cstf2t	NP_112539.2
Pan troglodytes (chimpanzee)	CSTF2T	XP_001163035.2
Homo sapiens (human)	CSTF2T	NP_056050.1
	CSTF2T	XP_001099871.1

Gene Ontology
Bibliography

Related articles in PubMed

sCLIP-an integrated platform to study RNA-protein interactomes in biomedical research: identification of CSTF2tau in alternative processing of small nuclear RNAs.
Kargapolova Y, Levin M, Lackner K, Danckwardt S
Nucleic acids research45(10)6074-6086(2017 Jun)

Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus.
Kariuki SN, Ghodke-Puranik Y, Dorschner JM, Chrabot BS, Kelly JA, Tsao BP, Kimberly RP, Alarc?n-Riquelme ME, Jacob CO, Criswell LA, Sivils KL, Langefeld CD, Harley JB, Skol AD, Niewold TB
Genes and immunity16(1)15-23(2015 Jan-Feb)

Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk.
Lindstr?m S, Thompson DJ, Paterson AD, Li J, Gierach GL, Scott C, Stone J, Douglas JA, dos-Santos-Silva I, Fernandez-Navarro P, Verghase J, Smith P, Brown J, Luben R, Wareham NJ, Loos RJ, Heit JA, Pankratz VS, Norman A, Goode EL, Cunningham JM, deAndrade M, Vierkant RA, Czene K, Fasching PA, Baglietto L, Southey MC, Giles GG, Shah KP, Chan HP, Helvie MA, Beck AH, Knoblauch NW, Hazra A, Hunter DJ, Kraft P, Pollan M, Figueroa JD, Couch FJ, Hopper JL, Hall P, Easton DF, Boyd NF, Vachon CM, Tamimi RM
Nature communications55303(2014 Oct)

Overlapping and distinct functions of CstF64 and CstF64? in mammalian mRNA 3' processing.
Yao C, Choi EA, Weng L, Xie X, Wan J, Xing Y, Moresco JJ, Tu PG, Yates JR 3rd, Shi Y
RNA (New York, N.Y.)19(12)1781-90(2013 Dec)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CSTF2tau binds many previously not recognized RNAs including histone, snoRNA and snRNAs. CSTF2tau-binding is associated with internal oligoadenylation resulting in shortened snRNA isoforms subjected to rapid degradation. CSTF2tau controls the abundance of snRNAs resulting in alternative splicing of several RNAs with critical roles in tumorigenesis and cardiac function.
Title: sCLIP-an integrated platform to study RNA-protein interactomes in biomedical research: identification of CSTF2tau in alternative processing of small nuclear RNAs.

CstF64 and CstF64tau modulate one another's expression and play overlapping as well as distinct roles in regulating global alternative polyadenylation profiles.
Title: Overlapping and distinct functions of CstF64 and CstF64? in mammalian mRNA 3' processing.

Studied expression levels of CstF-64 in EV71-infected cells; showed reduction of CstF-64 during virus infection correlated with production of viral 3C(pro). CstF-64 was cleaved in vitro by 3C(pro) not by mutant 3C(pro) variants.
Title: Enterovirus 71 3C protease cleaves a novel target CstF-64 and inhibits cellular polyadenylation.

Observational study of gene-disease association. (HuGE Navigator)
Title: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

upstream element in human papillomavirus type 16 interacted specifically with CstF-64, hnRNP C1/C2 & polypyrimidine tract binding protein, suggesting these factors were enhancing or regulating polyadenylation at the HPV-16 early polyadenylation signal
Title: A 57-nucleotide upstream early polyadenylation element in human papillomavirus type 16 interacts with hFip1, CstF-64, hnRNP C1/C2, and polypyrimidine tract binding protein.

The following CSTF2T gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CSTF2T cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29189	NM_015235.3 Latest version!	Homo sapiens cleavage stimulation factor subunit 2 tau variant (CSTF2T), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu29189	NM_015235.2	Homo sapiens cleavage stimulation factor subunit 2 tau variant (CSTF2T), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CSTF2T ( NM_015235.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_056050.1 Homo sapiens cleavage stimulation factor subunit 2 tau variant (CSTF2T), mRNA.

Price & Availability↑

CloneID	OHu29189
Clone ID Related Accession (Same CDS sequence)	NM_015235.2 , NM_015235.3
Accession Version	NM_015235.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1851bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Homo sapiens(human)
Product	cleavage stimulation factor subunit 2 tau variant
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI962669.1, AL136747.1, BX455090.1, AB014589.1 and BU743103.1. On Apr 2, 2004 this sequence version replaced NM_015235.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

ATGTCGAGTT TGGCGGTGAG AGACCCGGCA ATGGATCGAT CACTGCGTTC CGTGTTCGTG 
GGGAACATTC CATATGAGGC AACTGAGGAG CAGTTAAAGG ACATTTTCTC GGAGGTTGGT 
TCTGTTGTCA GTTTCCGGCT GGTATACGAT AGAGAGACGG GAAAACCCAA GGGCTATGGC 
TTCTGCGAAT ACCAAGACCA GGAGACCGCG CTTAGTGCCA TGCGGAACCT CAATGGGCGG 
GAGTTCAGTG GGAGAGCGCT TCGGGTGGAC AATGCTGCCA GTGAAAAGAA TAAGGAGGAG 
TTAAAGAGCC TTGGGCCTGC AGCGCCCATT ATTGACTCAC CCTATGGGGA TCCCATCGAT 
CCAGAAGATG CCCCTGAATC GATTACCAGA GCAGTAGCCA GTCTCCCCCC GGAGCAGATG 
TTTGAGCTGA TGAAGCAGAT GAAGCTCTGT GTCCAAAACA GCCACCAGGA AGCTCGAAAC 
ATGTTACTTC AAAATCCACA ACTGGCTTAT GCACTGTTGC AGGCACAAGT AGTGATGAGA 
ATCATGGATC CAGAGATTGC TCTGAAAATT CTGCATCGGA AGATACATGT CACACCACTG 
ATCCCAGGCA AATCTCAGTC TGTGTCTGTC TCTGGCCCTG GCCCTGGCCC TGGCCCTGGG 
CTCTGCCCAG GACCTAATGT TCTGCTGAAC CAGCAGAATC CTCCAGCTCC TCAGCCTCAG 
CATTTGGCTA GAAGACCTGT GAAGGACATT CCTCCTCTGA TGCAGACTCC TATCCAGGGT 
GGAATTCCAG CTCCAGGGCC AATACCAGCT GCAGTTCCCG GAGCTGGTCC TGGTTCCTTA 
ACTCCTGGAG GAGCAATGCA GCCCCAACTT GGAATGCCAG GGGTTGGCCC AGTGCCTTTA 
GAGCGGGGAC AAGTGCAGAT GTCAGATCCT AGAGCTCCTA TACCTCGCGG ACCCGTGACT 
CCTGGTGGTC TGCCTCCTCG AGGACTGTTA GGAGATGCTC CAAATGACCC ACGTGGAGGG 
ACTTTGCTTT CAGTCACTGG AGAAGTGGAG CCCAGAGGTT ATCTGGGTCC ACCCCATCAG 
GGTCCCCCCA TGCATCATGC CTCTGGTCAT GACACTCGTG GCCCTTCCTC ACATGAGATG 
AGGGGAGGGC CATTAGGAGA TCCCAGACTG CTAATTGGAG AGCCCAGAGG CCCCATGATA 
GATCAAAGGG GTCTACCTAT GGATGGTAGA GGTGGTAGAG ATTCTCGAGC GATGGAGACT 
CGTGCCATGG AAACTGAGGT CTTAGAGACA CGTGTAATGG AGAGGAGAGG AATGGAGACC 
TGTGCGATGG AAACCAGAGG GATGGAAGCA AGGGGCATGG ATGCAAGAGG ATTGGAGATG 
AGGGGCCCTG TCCCCAGTTC AAGAGGCCCT ATGACTGGTG GAATTCAGGG TCCTGGTCCC 
ATTAATATAG GGGCAGGTGG CCCTCCTCAG GGACCCAGAC AGGTCCCAGG CATTTCAGGG 
GTGGGGAATC CTGGAGCTGG TATGCAGGGT ACAGGCATAC AAGGAACAGG CATGCAGGGA 
GCAGGCATAC AAGGAGGAGG GATGCAGGGG GCAGGCATAC AAGGAGTCAG TATACAAGGA 
GGAGGTATAC AAGGAGGAGG TATACAGGGG GCAAGCAAGC AAGGTGGAAG CCAGCCTAGC 
AGTTTTAGTC CTGGGCAGAG CCAGGTCACT CCACAGGATC AGGAGAAGGC AGCTTTGATC 
ATGCAGGTTC TTCAACTGAC TGCAGATCAG ATTGCCATGC TGCCCCCTGA GCAAAGGCAG 
AGTATCCTGA TTTTAAAGGA ACAAATCCAG AAATCCACTG GAGCGTCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056050.1
CDS	47..1897
Translation	MSSLAVRDPAMDRSLRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDSPYGDPIDPEDAPESITRAVASLPPEQMFELMKQMKLCVQNSHQEARNMLLQNPQLAYALLQAQVVMRIMDPEIALKILHRKIHVTPLIPGKSQSVSVSGPGPGPGPGLCPGPNVLLNQQNPPAPQPQHLARRPVKDIPPLMQTPIQGGIPAPGPIPAAVPGAGPGSLTPGGAMQPQLGMPGVGPVPLERGQVQMSDPRAPIPRGPVTPGGLPPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQGPPMHHASGHDTRGPSSHEMRGGPLGDPRLLIGEPRGPMIDQRGLPMDGRGGRDSRAMETRAMETEVLETRVMERRGMETCAMETRGMEARGMDARGLEMRGPVPSSRGPMTGGIQGPGPINIGAGGPPQGPRQVPGISGVGNPGAGMQGTGIQGTGMQGAGIQGGGMQGAGIQGVSIQGGGIQGGGIQGASKQGGSQPSSFSPGQSQVTPQDQEKAALIMQVLQLTADQIAMLPPEQRQSILILKEQIQKSTGAS

Target ORF information:

RefSeq Version	NM_015235.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cleavage stimulation factor subunit 2 tau variant (CSTF2T), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015235.2

ORF Insert Sequence:

ATGTCGAGTT TGGCGGTGAG AGACCCGGCA ATGGATCGAT CACTGCGTTC CGTGTTCGTG 
GGGAACATTC CATATGAGGC AACTGAGGAG CAGTTAAAGG ACATTTTCTC GGAGGTTGGT 
TCTGTTGTCA GTTTCCGGCT GGTATACGAT AGAGAGACGG GAAAACCCAA GGGCTATGGC 
TTCTGCGAAT ACCAAGACCA GGAGACCGCG CTTAGTGCCA TGCGGAACCT CAATGGGCGG 
GAGTTCAGTG GGAGAGCGCT TCGGGTGGAC AATGCTGCCA GTGAAAAGAA TAAGGAGGAG 
TTAAAGAGCC TTGGGCCTGC AGCGCCCATT ATTGACTCAC CCTATGGGGA TCCCATCGAT 
CCAGAAGATG CCCCTGAATC GATTACCAGA GCAGTAGCCA GTCTCCCCCC GGAGCAGATG 
TTTGAGCTGA TGAAGCAGAT GAAGCTCTGT GTCCAAAACA GCCACCAGGA AGCTCGAAAC 
ATGTTACTTC AAAATCCACA ACTGGCTTAT GCACTGTTGC AGGCACAAGT AGTGATGAGA 
ATCATGGATC CAGAGATTGC TCTGAAAATT CTGCATCGGA AGATACATGT CACACCACTG 
ATCCCAGGCA AATCTCAGTC TGTGTCTGTC TCTGGCCCTG GCCCTGGCCC TGGCCCTGGG 
CTCTGCCCAG GACCTAATGT TCTGCTGAAC CAGCAGAATC CTCCAGCTCC TCAGCCTCAG 
CATTTGGCTA GAAGACCTGT GAAGGACATT CCTCCTCTGA TGCAGACTCC TATCCAGGGT 
GGAATTCCAG CTCCAGGGCC AATACCAGCT GCAGTTCCCG GAGCTGGTCC TGGTTCCTTA 
ACTCCTGGAG GAGCAATGCA GCCCCAACTT GGAATGCCAG GGGTTGGCCC AGTGCCTTTA 
GAGCGGGGAC AAGTGCAGAT GTCAGATCCT AGAGCTCCTA TACCTCGCGG ACCCGTGACT 
CCTGGTGGTC TGCCTCCTCG AGGACTGTTA GGAGATGCTC CAAATGACCC ACGTGGAGGG 
ACTTTGCTTT CAGTCACTGG AGAAGTGGAG CCCAGAGGTT ATCTGGGTCC ACCCCATCAG 
GGTCCCCCCA TGCATCATGC CTCTGGTCAT GACACTCGTG GCCCTTCCTC ACATGAGATG 
AGGGGAGGGC CATTAGGAGA TCCCAGACTG CTAATTGGAG AGCCCAGAGG CCCCATGATA 
GATCAAAGGG GTCTACCTAT GGATGGTAGA GGTGGTAGAG ATTCTCGAGC GATGGAGACT 
CGTGCCATGG AAACTGAGGT CTTAGAGACA CGTGTAATGG AGAGGAGAGG AATGGAGACC 
TGTGCGATGG AAACCAGAGG GATGGAAGCA AGGGGCATGG ATGCAAGAGG ATTGGAGATG 
AGGGGCCCTG TCCCCAGTTC AAGAGGCCCT ATGACTGGTG GAATTCAGGG TCCTGGTCCC 
ATTAATATAG GGGCAGGTGG CCCTCCTCAG GGACCCAGAC AGGTCCCAGG CATTTCAGGG 
GTGGGGAATC CTGGAGCTGG TATGCAGGGT ACAGGCATAC AAGGAACAGG CATGCAGGGA 
GCAGGCATAC AAGGAGGAGG GATGCAGGGG GCAGGCATAC AAGGAGTCAG TATACAAGGA 
GGAGGTATAC AAGGAGGAGG TATACAGGGG GCAAGCAAGC AAGGTGGAAG CCAGCCTAGC 
AGTTTTAGTC CTGGGCAGAG CCAGGTCACT CCACAGGATC AGGAGAAGGC AGCTTTGATC 
ATGCAGGTTC TTCAACTGAC TGCAGATCAG ATTGCCATGC TGCCCCCTGA GCAAAGGCAG 
AGTATCCTGA TTTTAAAGGA ACAAATCCAG AAATCCACTG GAGCGTCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CSTF2T ( NM_015235.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_056050.1 Homo sapiens cleavage stimulation factor subunit 2 tau variant (CSTF2T), mRNA.

Price & Availability↑

CloneID	OHu29189
Clone ID Related Accession (Same CDS sequence)	NM_015235.2 , NM_015235.3
Accession Version	NM_015235.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1851bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	cleavage stimulation factor subunit 2 tau variant
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI962669.1, AL136747.1, BX455090.1, AB014589.1 and BU743103.1. On May 17, 2019 this sequence version replaced NM_015235.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: SRR1803616.132899.1, SRR1660805.224807.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000331173.6/ ENSP00000332444.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGTCGAGTT TGGCGGTGAG AGACCCGGCA ATGGATCGAT CACTGCGTTC CGTGTTCGTG 
GGGAACATTC CATATGAGGC AACTGAGGAG CAGTTAAAGG ACATTTTCTC GGAGGTTGGT 
TCTGTTGTCA GTTTCCGGCT GGTATACGAT AGAGAGACGG GAAAACCCAA GGGCTATGGC 
TTCTGCGAAT ACCAAGACCA GGAGACCGCG CTTAGTGCCA TGCGGAACCT CAATGGGCGG 
GAGTTCAGTG GGAGAGCGCT TCGGGTGGAC AATGCTGCCA GTGAAAAGAA TAAGGAGGAG 
TTAAAGAGCC TTGGGCCTGC AGCGCCCATT ATTGACTCAC CCTATGGGGA TCCCATCGAT 
CCAGAAGATG CCCCTGAATC GATTACCAGA GCAGTAGCCA GTCTCCCCCC GGAGCAGATG 
TTTGAGCTGA TGAAGCAGAT GAAGCTCTGT GTCCAAAACA GCCACCAGGA AGCTCGAAAC 
ATGTTACTTC AAAATCCACA ACTGGCTTAT GCACTGTTGC AGGCACAAGT AGTGATGAGA 
ATCATGGATC CAGAGATTGC TCTGAAAATT CTGCATCGGA AGATACATGT CACACCACTG 
ATCCCAGGCA AATCTCAGTC TGTGTCTGTC TCTGGCCCTG GCCCTGGCCC TGGCCCTGGG 
CTCTGCCCAG GACCTAATGT TCTGCTGAAC CAGCAGAATC CTCCAGCTCC TCAGCCTCAG 
CATTTGGCTA GAAGACCTGT GAAGGACATT CCTCCTCTGA TGCAGACTCC TATCCAGGGT 
GGAATTCCAG CTCCAGGGCC AATACCAGCT GCAGTTCCCG GAGCTGGTCC TGGTTCCTTA 
ACTCCTGGAG GAGCAATGCA GCCCCAACTT GGAATGCCAG GGGTTGGCCC AGTGCCTTTA 
GAGCGGGGAC AAGTGCAGAT GTCAGATCCT AGAGCTCCTA TACCTCGCGG ACCCGTGACT 
CCTGGTGGTC TGCCTCCTCG AGGACTGTTA GGAGATGCTC CAAATGACCC ACGTGGAGGG 
ACTTTGCTTT CAGTCACTGG AGAAGTGGAG CCCAGAGGTT ATCTGGGTCC ACCCCATCAG 
GGTCCCCCCA TGCATCATGC CTCTGGTCAT GACACTCGTG GCCCTTCCTC ACATGAGATG 
AGGGGAGGGC CATTAGGAGA TCCCAGACTG CTAATTGGAG AGCCCAGAGG CCCCATGATA 
GATCAAAGGG GTCTACCTAT GGATGGTAGA GGTGGTAGAG ATTCTCGAGC GATGGAGACT 
CGTGCCATGG AAACTGAGGT CTTAGAGACA CGTGTAATGG AGAGGAGAGG AATGGAGACC 
TGTGCGATGG AAACCAGAGG GATGGAAGCA AGGGGCATGG ATGCAAGAGG ATTGGAGATG 
AGGGGCCCTG TCCCCAGTTC AAGAGGCCCT ATGACTGGTG GAATTCAGGG TCCTGGTCCC 
ATTAATATAG GGGCAGGTGG CCCTCCTCAG GGACCCAGAC AGGTCCCAGG CATTTCAGGG 
GTGGGGAATC CTGGAGCTGG TATGCAGGGT ACAGGCATAC AAGGAACAGG CATGCAGGGA 
GCAGGCATAC AAGGAGGAGG GATGCAGGGG GCAGGCATAC AAGGAGTCAG TATACAAGGA 
GGAGGTATAC AAGGAGGAGG TATACAGGGG GCAAGCAAGC AAGGTGGAAG CCAGCCTAGC 
AGTTTTAGTC CTGGGCAGAG CCAGGTCACT CCACAGGATC AGGAGAAGGC AGCTTTGATC 
ATGCAGGTTC TTCAACTGAC TGCAGATCAG ATTGCCATGC TGCCCCCTGA GCAAAGGCAG 
AGTATCCTGA TTTTAAAGGA ACAAATCCAG AAATCCACTG GAGCGTCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056050.1
CDS	47..1897
Translation	MSSLAVRDPAMDRSLRSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDSPYGDPIDPEDAPESITRAVASLPPEQMFELMKQMKLCVQNSHQEARNMLLQNPQLAYALLQAQVVMRIMDPEIALKILHRKIHVTPLIPGKSQSVSVSGPGPGPGPGLCPGPNVLLNQQNPPAPQPQHLARRPVKDIPPLMQTPIQGGIPAPGPIPAAVPGAGPGSLTPGGAMQPQLGMPGVGPVPLERGQVQMSDPRAPIPRGPVTPGGLPPRGLLGDAPNDPRGGTLLSVTGEVEPRGYLGPPHQGPPMHHASGHDTRGPSSHEMRGGPLGDPRLLIGEPRGPMIDQRGLPMDGRGGRDSRAMETRAMETEVLETRVMERRGMETCAMETRGMEARGMDARGLEMRGPVPSSRGPMTGGIQGPGPINIGAGGPPQGPRQVPGISGVGNPGAGMQGTGIQGTGMQGAGIQGGGMQGAGIQGVSIQGGGIQGGGIQGASKQGGSQPSSFSPGQSQVTPQDQEKAALIMQVLQLTADQIAMLPPEQRQSILILKEQIQKSTGAS

Target ORF information:

RefSeq Version	NM_015235.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cleavage stimulation factor subunit 2 tau variant (CSTF2T), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015235.3

ORF Insert Sequence:

ATGTCGAGTT TGGCGGTGAG AGACCCGGCA ATGGATCGAT CACTGCGTTC CGTGTTCGTG 
GGGAACATTC CATATGAGGC AACTGAGGAG CAGTTAAAGG ACATTTTCTC GGAGGTTGGT 
TCTGTTGTCA GTTTCCGGCT GGTATACGAT AGAGAGACGG GAAAACCCAA GGGCTATGGC 
TTCTGCGAAT ACCAAGACCA GGAGACCGCG CTTAGTGCCA TGCGGAACCT CAATGGGCGG 
GAGTTCAGTG GGAGAGCGCT TCGGGTGGAC AATGCTGCCA GTGAAAAGAA TAAGGAGGAG 
TTAAAGAGCC TTGGGCCTGC AGCGCCCATT ATTGACTCAC CCTATGGGGA TCCCATCGAT 
CCAGAAGATG CCCCTGAATC GATTACCAGA GCAGTAGCCA GTCTCCCCCC GGAGCAGATG 
TTTGAGCTGA TGAAGCAGAT GAAGCTCTGT GTCCAAAACA GCCACCAGGA AGCTCGAAAC 
ATGTTACTTC AAAATCCACA ACTGGCTTAT GCACTGTTGC AGGCACAAGT AGTGATGAGA 
ATCATGGATC CAGAGATTGC TCTGAAAATT CTGCATCGGA AGATACATGT CACACCACTG 
ATCCCAGGCA AATCTCAGTC TGTGTCTGTC TCTGGCCCTG GCCCTGGCCC TGGCCCTGGG 
CTCTGCCCAG GACCTAATGT TCTGCTGAAC CAGCAGAATC CTCCAGCTCC TCAGCCTCAG 
CATTTGGCTA GAAGACCTGT GAAGGACATT CCTCCTCTGA TGCAGACTCC TATCCAGGGT 
GGAATTCCAG CTCCAGGGCC AATACCAGCT GCAGTTCCCG GAGCTGGTCC TGGTTCCTTA 
ACTCCTGGAG GAGCAATGCA GCCCCAACTT GGAATGCCAG GGGTTGGCCC AGTGCCTTTA 
GAGCGGGGAC AAGTGCAGAT GTCAGATCCT AGAGCTCCTA TACCTCGCGG ACCCGTGACT 
CCTGGTGGTC TGCCTCCTCG AGGACTGTTA GGAGATGCTC CAAATGACCC ACGTGGAGGG 
ACTTTGCTTT CAGTCACTGG AGAAGTGGAG CCCAGAGGTT ATCTGGGTCC ACCCCATCAG 
GGTCCCCCCA TGCATCATGC CTCTGGTCAT GACACTCGTG GCCCTTCCTC ACATGAGATG 
AGGGGAGGGC CATTAGGAGA TCCCAGACTG CTAATTGGAG AGCCCAGAGG CCCCATGATA 
GATCAAAGGG GTCTACCTAT GGATGGTAGA GGTGGTAGAG ATTCTCGAGC GATGGAGACT 
CGTGCCATGG AAACTGAGGT CTTAGAGACA CGTGTAATGG AGAGGAGAGG AATGGAGACC 
TGTGCGATGG AAACCAGAGG GATGGAAGCA AGGGGCATGG ATGCAAGAGG ATTGGAGATG 
AGGGGCCCTG TCCCCAGTTC AAGAGGCCCT ATGACTGGTG GAATTCAGGG TCCTGGTCCC 
ATTAATATAG GGGCAGGTGG CCCTCCTCAG GGACCCAGAC AGGTCCCAGG CATTTCAGGG 
GTGGGGAATC CTGGAGCTGG TATGCAGGGT ACAGGCATAC AAGGAACAGG CATGCAGGGA 
GCAGGCATAC AAGGAGGAGG GATGCAGGGG GCAGGCATAC AAGGAGTCAG TATACAAGGA 
GGAGGTATAC AAGGAGGAGG TATACAGGGG GCAAGCAAGC AAGGTGGAAG CCAGCCTAGC 
AGTTTTAGTC CTGGGCAGAG CCAGGTCACT CCACAGGATC AGGAGAAGGC AGCTTTGATC 
ATGCAGGTTC TTCAACTGAC TGCAGATCAG ATTGCCATGC TGCCCCCTGA GCAAAGGCAG 
AGTATCCTGA TTTTAAAGGA ACAAATCCAG AAATCCACTG GAGCGTCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

sCLIP-an integrated platform to study RNA-protein interactomes in biomedical research: identification of CSTF2tau in alternative processing of small nuclear RNAs.
Nucleic acids research45(10)6074-6086(2017 Jun)
Kargapolova Y,Levin M,Lackner K,Danckwardt S

Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus.
Genes and immunity16(1)15-23(2015 Jan-Feb)
Kariuki SN,Ghodke-Puranik Y,Dorschner JM,Chrabot BS,Kelly JA,Tsao BP,Kimberly RP,Alarc?n-Riquelme ME,Jacob CO,Criswell LA,Sivils KL,Langefeld CD,Harley JB,Skol AD,Niewold TB

Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk.
Nature communications55303(2014 Oct)
Lindstr?m S,Thompson DJ,Paterson AD,Li J,Gierach GL,Scott C,Stone J,Douglas JA,dos-Santos-Silva I,Fernandez-Navarro P,Verghase J,Smith P,Brown J,Luben R,Wareham NJ,Loos RJ,Heit JA,Pankratz VS,Norman A,Goode EL,Cunningham JM,deAndrade M,Vierkant RA,Czene K,Fasching PA,Baglietto L,Southey MC,Giles GG,Shah KP,Chan HP,Helvie MA,Beck AH,Knoblauch NW,Hazra A,Hunter DJ,Kraft P,Pollan M,Figueroa JD,Couch FJ,Hopper JL,Hall P,Easton DF,Boyd NF,Vachon CM,Tamimi RM

Overlapping and distinct functions of CstF64 and CstF64? in mammalian mRNA 3' processing.
RNA (New York, N.Y.)19(12)1781-90(2013 Dec)
Yao C,Choi EA,Weng L,Xie X,Wan J,Xing Y,Moresco JJ,Tu PG,Yates JR 3rd,Shi Y

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M

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CSTF2T cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

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