NUP160 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NUP160
Entrez Gene ID	23279
Full Name	nucleoporin 160
General protein information	Preferred Names nucleoporin 160 Names nuclear pore complex protein Nup160 160 kDa nucleoporin nucleoporin 160kD nucleoporin 160kDa nucleoporin Nup160
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p11.2
Summary	NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic transport.[supplied by OMIM, Apr 2004].
Disorder MIM:	607614

mRNA and Protein(s)

mRNA	Protein	Name
NM_015231.2	NP_056046.1	nuclear pore complex protein Nup160 isoform 1
NM_001318399.1	NP_001305328.1	nuclear pore complex protein Nup160 isoform 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	NUP160	NP_056046.1
Pan troglodytes (chimpanzee)	NUP160	XP_001170076.1
Canis lupus familiaris (dog)	NUP160	XP_005631785.1
Bos taurus (cattle)	NUP160	NP_001099100.1
Rattus norvegicus (Norway rat)	Nup160	NP_001101214.1
Drosophila melanogaster (fruit fly)	Nup160	NP_609493.1
Mus musculus (house mouse)	Nup160	NP_067487.1
Gallus gallus (chicken)	NUP160	XP_001232607.3
Danio rerio (zebrafish)	nup160	NP_956956.1

Gene Ontology
Bibliography

Related articles in PubMed

NUP160-SLC43A3 is a novel recurrent fusion oncogene in angiosarcoma.
Shimozono N, Jinnin M, Masuzawa M, Masuzawa M, Wang Z, Hirano A, Tomizawa Y, Etoh-Kira T, Kajihara I, Harada M, Fukushima S, Ihn H
Cancer research75(21)4458-65(2015 Nov)

Intranuclear dynamics of the Nup107-160 complex.
Morchoisne-Bolhy S, Geoffroy MC, Bouhlel IB, Alves A, Audug? N, Baudin X, Van Bortle K, Powers MA, Doye V
Molecular biology of the cell26(12)2343-56(2015 Jun)

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma.
Hysi PG, Cheng CY, Springelkamp H, Macgregor S, Bailey JNC, Wojciechowski R, Vitart V, Nag A, Hewitt AW, H?hn R, Venturini C, Mirshahi A, Ramdas WD, Thorleifsson G, Vithana E, Khor CC, Stefansson AB, Liao J, Haines JL, Amin N, Wang YX, Wild PS, Ozel AB, Li JZ, Fleck BW, Zeller T, Staffieri SE, Teo YY, Cuellar-Partida G, Luo X, Allingham RR, Richards JE, Senft A, Karssen LC, Zheng Y, Bellenguez C, Xu L, Iglesias AI, Wilson JF, Kang JH, van Leeuwen EM, Jonsson V, Thorsteinsdottir U, Despriet DDG, Ennis S, Moroi SE, Martin NG, Jansonius NM, Yazar S, Tai ES, Amouyel P, Kirwan J, van Koolwijk LME, Hauser MA, Jonasson F, Leo P, Loomis SJ, Fogarty R, Rivadeneira F, Kearns L, Lackner KJ, de Jong PTVM, Simpson CL, Pennell CE, Oostra BA, Uitterlinden AG, Saw SM, Lotery AJ, Bailey-Wilson JE, Hofman A, Vingerling JR, Maubaret C, Pfeiffer N, Wolfs RCW, Lemij HG, Young TL, Pasquale LR, Delcourt C, Spector TD, Klaver CCW, Small KS, Burdon KP, Stefansson K, Wong TY, , , , Viswanathan A, Mackey DA, Craig JE, Wiggs JL, van Duijn CM, Hammond CJ, Aung T
Nature genetics46(10)1126-1130(2014 Oct)

The SUMO-specific isopeptidase SENP2 associates dynamically with nuclear pore complexes through interactions with karyopherins and the Nup107-160 nucleoporin subcomplex.
Goeres J, Chan PK, Mukhopadhyay D, Zhang H, Raught B, Matunis MJ
Molecular biology of the cell22(24)4868-82(2011 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

transcriptome sequencing of patient-derived angiosarcoma cells, identified a novel fusion gene NUP160-SLC43A3 found to be expressed in 9 of 25 human angiosarcoma specimens that were examined.
Title: NUP160-SLC43A3 is a novel recurrent fusion oncogene in angiosarcoma.

Nup107-160 complex and its partner Elys dynamically colocalize with Nup98 and CRM1 into endogenous GLFG bodies present in specific HeLa sublines.
Title: Intranuclear dynamics of the Nup107-160 complex.

The SUMO-specific isopeptidase SENP2 associates dynamically with nuclear pore complexes through interactions with karyopherins and the Nup107-160 nucleoporin subcomplex.
Title: The SUMO-specific isopeptidase SENP2 associates dynamically with nuclear pore complexes through interactions with karyopherins and the Nup107-160 nucleoporin subcomplex.

The interactions of Nup160 with Pom121 and are predicted to assist in the formation of the nuclear pore and the anchoring of the Nuclear pore complexes to the pore membrane.
Title: Pom121 links two essential subcomplexes of the nuclear pore complex core to the membrane.

Data show that Nup107-160 promotes spindle assembly through Ran-GTP-regulated nucleation of microtubules by gamma-TuRC at kinetochores, and reveal a relationship between nucleoporins and the microtubule cytoskeleton.
Title: The Nup107-160 complex and gamma-TuRC regulate microtubule polymerization at kinetochores.

The following NUP160 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NUP160 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu101469	NM_001318399.1 Latest version!	Homo sapiens nucleoporin 160 (NUP160), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu26449	NM_015231.2 Latest version!	Homo sapiens nucleoporin 160 (NUP160), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$384.30 $549.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NUP160 ( NM_001318399.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001305328.1 Homo sapiens nucleoporin 160 (NUP160), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu101469
Clone ID Related Accession (Same CDS sequence)	NM_001318399.1
Accession Version	NM_001318399.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 675bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	nuclear pore complex protein Nup160 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI559779.1, BC009822.2 and AK026236.1. Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK026236.1, SRR1163658.230884.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTTCACC TGTCCGCAGC TCCGCCCGCC CCACCCCCGG AAGTGACGGC GACCGCGCGG 
CCCTGCCTTT GTTCCGTTGG GCGTCGCGGC GACGGCGGGA AGATGGCGGC GGCGGGAGCC 
CTGGAACGGA GCTTCGTGGA GCTAAGCGGA GCTGAGCGCG AAAGGCCGAG GCACTTTCGG 
GAATTCACAG TCTGCAGCAT TGGGACTGCA AATGCCGTGG CTGGCGCCGT AAAATACAGT 
GAAAGCGCGG GAGGCTTTTA CTACGTGGAG AGTGGCAAGT TGTTCTCCGT AACCAGAAAC 
AGGTTCATTC ATTGGAAGAC CTCTGGAGAT ACATTGGAGC TGATGGAGGA GTCACTGGAC 
ATAAATCTGT TGAATAATGC CATTCGCCTA AAATTCCAAA ATTGCAGTGT TTTACCTGGA 
GGGGTTTATG TCTCTGAGAC TCAGAATCGT GTGATAATCT TGATGTTAAC CAATCAAACA 
GTGCACAGGT TACTTTTACC ACACCCCTCC CGGATGTATA GGAGTGTAAG TTGGCTAAGT 
GCAATATCTT TTATTTCCCA AATTACTCTG GGTGTCACAA ATGTAGTGCT GGAGCGATGT 
CTTTTGGAAT TGAAGGAAAT TTGGATTCTC GTTATCCCTC ACCAAGCATA CTTTGATAGC 
TACCGCTTAA AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001305328.1
CDS	125..799
Translation	MLHLSAAPPAPPPEVTATARPCLCSVGRRGDGGKMAAAGALERSFVELSGAERERPRHFREFTVCSIGTANAVAGAVKYSESAGGFYYVESGKLFSVTRNRFIHWKTSGDTLELMEESLDINLLNNAIRLKFQNCSVLPGGVYVSETQNRVIILMLTNQTVHRLLLPHPSRMYRSVSWLSAISFISQITLGVTNVVLERCLLELKEIWILVIPHQAYFDSYRLK

Target ORF information:

RefSeq Version	NM_001318399.1
Organism	Homo sapiens(human)
Definition	Homo sapiens nucleoporin 160 (NUP160), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001318399.1

ORF Insert Sequence:

ATGCTTCACC TGTCCGCAGC TCCGCCCGCC CCACCCCCGG AAGTGACGGC GACCGCGCGG 
CCCTGCCTTT GTTCCGTTGG GCGTCGCGGC GACGGCGGGA AGATGGCGGC GGCGGGAGCC 
CTGGAACGGA GCTTCGTGGA GCTAAGCGGA GCTGAGCGCG AAAGGCCGAG GCACTTTCGG 
GAATTCACAG TCTGCAGCAT TGGGACTGCA AATGCCGTGG CTGGCGCCGT AAAATACAGT 
GAAAGCGCGG GAGGCTTTTA CTACGTGGAG AGTGGCAAGT TGTTCTCCGT AACCAGAAAC 
AGGTTCATTC ATTGGAAGAC CTCTGGAGAT ACATTGGAGC TGATGGAGGA GTCACTGGAC 
ATAAATCTGT TGAATAATGC CATTCGCCTA AAATTCCAAA ATTGCAGTGT TTTACCTGGA 
GGGGTTTATG TCTCTGAGAC TCAGAATCGT GTGATAATCT TGATGTTAAC CAATCAAACA 
GTGCACAGGT TACTTTTACC ACACCCCTCC CGGATGTATA GGAGTGTAAG TTGGCTAAGT 
GCAATATCTT TTATTTCCCA AATTACTCTG GGTGTCACAA ATGTAGTGCT GGAGCGATGT 
CTTTTGGAAT TGAAGGAAAT TTGGATTCTC GTTATCCCTC ACCAAGCATA CTTTGATAGC 
TACCGCTTAA AATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NUP160 ( NM_015231.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_056046.1 Homo sapiens nucleoporin 160 (NUP160), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu26449
Clone ID Related Accession (Same CDS sequence)	NM_015231.2
Accession Version	NM_015231.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4311bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	nuclear pore complex protein Nup160 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI559779.1, BC125227.1, AC021443.27, BX647634.1 and CN420734.1. On Jan 6, 2016 this sequence version replaced NM_015231.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.17491.1, SRR1660809.108039.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTTCACC TGTCCGCAGC TCCGCCCGCC CCACCCCCGG AAGTGACGGC GACCGCGCGG 
CCCTGCCTTT GTTCCGTTGG GCGTCGCGGC GACGGCGGGA AGATGGCGGC GGCGGGAGCC 
CTGGAACGGA GCTTCGTGGA GCTAAGCGGA GCTGAGCGCG AAAGGCCGAG GCACTTTCGG 
GAATTCACAG TCTGCAGCAT TGGGACTGCA AATGCCGTGG CTGGCGCCGT AAAATACAGT 
GAAAGCGCGG GAGGCTTTTA CTACGTGGAG AGTGGCAAGT TGTTCTCCGT AACCAGAAAC 
AGGTTCATTC ATTGGAAGAC CTCTGGAGAT ACATTGGAGC TGATGGAGGA GTCACTGGAC 
ATAAATCTGT TGAATAATGC CATTCGCCTA AAATTCCAAA ATTGCAGTGT TTTACCTGGA 
GGGGTTTATG TCTCTGAGAC TCAGAATCGT GTGATAATCT TGATGTTAAC CAATCAAACA 
GTGCACAGGT TACTTTTACC ACACCCCTCC CGGATGTATA GGAGTGAGTT GGTAGTTGAC 
AGTCAGATGC AGTCAATATT CACTGACATT GGAAAAGTTG ATTTCACAGA TCCTTGCAAC 
TATCAGTTAA TTCCAGCAGT ACCTGGAATA TCTCCTAATT CCACCGCCTC TACAGCCTGG 
CTCAGCAGTG ATGGGGAGGC CCTGTTTGCC TTACCATGTG CTTCTGGGGG AATCTTTGTT 
CTTAAGCTAC CTCCTTATGA CATACCTGGT ATGGTGTCAG TCGTGGAACT GAAACAGAGT 
TCAGTAATGC AACGATTGCT TACAGGCTGG ATGCCAACAG CTATCAGGGG TGACCAGTCG 
CCTTCAGATC GTCCCCTCAG TCTTGCTGTT CATTGTGTGG AGCATGATGC CTTCATCTTT 
GCTTTGTGTC AGGATCATAA ACTACGAATG TGGTCTTACA AGGAGCAAAT GTGCCTAATG 
GTAGCTGACA TGCTGGAGTA TGTCCCTGTG AAGAAAGACC TTCGGCTTAC TGCTGGAACT 
GGACACAAAT TACGGCTTGC TTATTCCCCC ACCATGGGAC TCTACCTGGG GATATACATG 
CATGCACCAA AACGAGGACA GTTCTGCATT TTCCAGTTGG TGAGCACTGA GAGTAATCGC 
TATAGTCTCG ATCATATTTC TTCACTGTTC ACTTCTCAGG AGACACTGAT TGACTTTGCC 
TTAACTTCCA CGGATATCTG GGCCCTGTGG CATGATGCTG AGAACCAAAC AGTAGTGAAA 
TACATCAACT TTGAACATAA TGTTGCAGGT CAGTGGAATC CAGTTTTTAT GCAGCCTCTG 
CCAGAGGAAG AGATTGTCAT CAGAGATGAT CAAGACCCCA GAGAGATGTA TCTGCAAAGT 
CTTTTTACAC CAGGACAATT CACAAATGAA GCTTTATGTA AGGCTTTACA GATTTTCTGC 
CGAGGAACTG AGAGGAATTT GGATCTTTCC TGGAGTGAAC TGAAGAAAGA AGTTACTTTA 
GCTGTTGAAA ATGAGCTTCA AGGAAGTGTA ACAGAGTATG AATTCTCCCA GGAGGAGTTT 
CGAAATTTAC AACAAGAATT CTGGTGCAAG TTCTATGCCT GTTGTCTTCA GTATCAAGAA 
GCCCTCTCTC ACCCTCTTGC CCTACATTTG AATCCACACA CAAACATGGT GTGCCTGCTG 
AAAAAAGGGT ACCTGTCTTT CCTTATTCCC TCATCCTTAG TGGATCATTT GTATCTCCTG 
CCTTATGAGA ACCTTTTGAC AGAAGATGAG ACAACCATAT CTGATGATGT GGATATCGCT 
CGGGATGTCA TATGTCTTAT AAAATGCCTC CGGCTGATTG AAGAGTCAGT AACTGTGGAT 
ATGTCAGTTA TAATGGAAAT GAGTTGTTAT AACCTACAGT CTCCGGAAAA GGCTGCAGAG 
CAGATTCTGG AAGATATGAT CACTATTGAT GTAGAAAATG TGATGGAGGA TATTTGTAGT 
AAACTGCAAG AGATTAGGAA CCCAATCCAT GCAATTGGAC TACTTATACG GGAAATGGAT 
TATGAAACAG AAGTGGAAAT GGAAAAGGGA TTCAATCCAG CTCAGCCTTT GAATATTCGA 
ATGAATCTTA CCCAGCTCTA TGGTAGTAAC ACAGCAGGGT ATATTGTGTG CAGAGGGGTG 
CATAAAATCG CCAGTACTCG TTTCCTGATC TGCAGAGATC TTTTGATCTT ACAGCAGCTG 
TTAATGAGGC TTGGAGATGC TGTGATTTGG GGAACTGGTC AGCTCTTTCA AGCTCAGCAA 
GACCTACTAC ATCGAACAGC TCCCCTACTC TTATCTTATT ACCTCATTAA ATGGGGAAGT 
GAGTGCTTGG CAACTGATGT TCCACTTGAC ACACTGGAGT CTAATCTCCA ACACTTATCA 
GTACTGGAAT TAACAGACTC TGGTGCTTTA ATGGCAAATA GGTTTGTATC TAGTCCTCAG 
ACTATTGTGG AGTTATTCTT CCAAGAAGTT GCAAGAAAAC ACATTATATC TCACCTCTTC 
TCTCAGCCAA AGGCACCTCT GAGCCAAACT GGATTGAATT GGCCTGAAAT GATTACTGCA 
ATTACCAGTT ATTTATTGCA GCTTTTATGG CCTAGCAATC CTGGTTGTCT CTTTCTAGAA 
TGTTTGATGG GAAATTGCCA ATATGTACAA TTGCAGGATT ATATTCAACT GCTACATCCC 
TGGTGTCAAG TCAATGTTGG TTCCTGTCGA TTTATGCTGG GAAGGTGTTA CCTAGTTACA 
GGAGAAGGAC AGAAGGCTCT GGAATGTTTT TGTCAGGCAG CATCTGAAGT AGGCAAAGAG 
GAATTCTTGG ATCGCTTGAT TCGCTCAGAG GATGGGGAGA TCGTGTCTAC CCCCAGGCTG 
CAGTATTATG ACAAGGTTTT ACGACTACTA GATGTCATTG GTTTGCCTGA ACTGGTTATT 
CAGTTGGCTA CATCAGCCAT AACTGAAGCA GGTGATGACT GGAAAAGTCA GGCTACTCTA 
AGGACATGTA TTTTCAAACA TCATTTGGAT TTGGGTCACA ATAGCCAAGC ATATGAAGCC 
TTAACCCAAA TTCCTGATTC CAGCAGGCAA TTAGATTGTT TACGGCAGTT GGTGGTAGTT 
CTTTGTGAAC GCTCACAGCT ACAGGATCTT GTAGAGTTTC CCTATGTGAA TCTGCATAAT 
GAGGTTGTGG GAATAATTGA GTCACGTGCT AGAGCTGTGG ACCTTATGAC TCACAATTAC 
TATGAACTTC TGTATGCCTT TCACATCTAT CGCCACAATT ACCGCAAGGC TGGCACAGTG 
ATGTTTGAGT ATGGAATGCG GCTTGGCAGA GAAGTTCGAA CTCTCCGGGG ACTTGAGAAA 
CAAGGCAACT GTTATCTGGC TGCTCTCAAT TGTTTACGAC TTATTCGTCC AGAATATGCG 
TGGATTGTGC AGCCAGTGTC TGGTGCAGTG TATGATCGCC CTGGAGCATC CCCTAAGAGG 
AATCATGATG GAGAATGCAC AGCTGCCCCC ACAAATCGAC AAATTGAAAT CCTGGAACTG 
GAAGATCTGG AGAAAGAGTG TTCCTTGGCT CGCATCCGCC TCACTTTGGC TCAGCATGAT 
CCATCAGCGG TTGCAGTTGC TGGAAGTTCA TCAGCAGAGG AAATGGTCAC TCTCTTGGTT 
CAGGCGGGCC TCTTTGACAC TGCCATATCA CTCTGTCAGA CTTTTAAGCT TCCCTTAACG 
CCAGTCTTTG AAGGGCTTGC CTTCAAATGC ATCAAATTGC AATTTGGAGG AGAGGCAGCA 
CAAGCAGAAG CCTGGGCCTG GCTAGCAGCC AATCAGCTCT CATCTGTCAT CACTACTAAG 
GAGTCTAGTG CTACAGATGA AGCATGGCGA CTATTATCCA CTTACCTGGA GAGGTACAAA 
GTCCAGAATA ACTTGTATCA CCACTGTGTA ATCAACAAGC TCTTGTCTCA TGGAGTGCCT 
CTGCCTAATT GGCTTATAAA CAGTTACAAG AAGGTTGATG CTGCTGAATT GCTTCGTTTA 
TACTTAAACT ATGACCTTTT AGAAGAAGCT GTGGATTTGG TGTCAGAATA TGTGGATGCT 
GTATTGGGAA AAGGACATCA ATACTTCGGA ATTGAGTTTC CACTGTCCGC AACAGCCCCA 
ATGGTGTGGC TTCCATACTC CTCTATTGAT CAGCTTCTCC AAGCTCTGGG AGAGAACAGT 
GCCAACAGTC ACAACATCGC ACTGTCCCAG AAAATACTTG ACAAATTGGA GGACTACCAG 
CAAAAAGTTG ATAAGGCAAC ACGGGATTTA TTATATCGTC GGACCTTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056046.1
CDS	125..4435
Translation	MLHLSAAPPAPPPEVTATARPCLCSVGRRGDGGKMAAAGALERSFVELSGAERERPRHFREFTVCSIGTANAVAGAVKYSESAGGFYYVESGKLFSVTRNRFIHWKTSGDTLELMEESLDINLLNNAIRLKFQNCSVLPGGVYVSETQNRVIILMLTNQTVHRLLLPHPSRMYRSELVVDSQMQSIFTDIGKVDFTDPCNYQLIPAVPGISPNSTASTAWLSSDGEALFALPCASGGIFVLKLPPYDIPGMVSVVELKQSSVMQRLLTGWMPTAIRGDQSPSDRPLSLAVHCVEHDAFIFALCQDHKLRMWSYKEQMCLMVADMLEYVPVKKDLRLTAGTGHKLRLAYSPTMGLYLGIYMHAPKRGQFCIFQLVSTESNRYSLDHISSLFTSQETLIDFALTSTDIWALWHDAENQTVVKYINFEHNVAGQWNPVFMQPLPEEEIVIRDDQDPREMYLQSLFTPGQFTNEALCKALQIFCRGTERNLDLSWSELKKEVTLAVENELQGSVTEYEFSQEEFRNLQQEFWCKFYACCLQYQEALSHPLALHLNPHTNMVCLLKKGYLSFLIPSSLVDHLYLLPYENLLTEDETTISDDVDIARDVICLIKCLRLIEESVTVDMSVIMEMSCYNLQSPEKAAEQILEDMITIDVENVMEDICSKLQEIRNPIHAIGLLIREMDYETEVEMEKGFNPAQPLNIRMNLTQLYGSNTAGYIVCRGVHKIASTRFLICRDLLILQQLLMRLGDAVIWGTGQLFQAQQDLLHRTAPLLLSYYLIKWGSECLATDVPLDTLESNLQHLSVLELTDSGALMANRFVSSPQTIVELFFQEVARKHIISHLFSQPKAPLSQTGLNWPEMITAITSYLLQLLWPSNPGCLFLECLMGNCQYVQLQDYIQLLHPWCQVNVGSCRFMLGRCYLVTGEGQKALECFCQAASEVGKEEFLDRLIRSEDGEIVSTPRLQYYDKVLRLLDVIGLPELVIQLATSAITEAGDDWKSQATLRTCIFKHHLDLGHNSQAYEALTQIPDSSRQLDCLRQLVVVLCERSQLQDLVEFPYVNLHNEVVGIIESRARAVDLMTHNYYELLYAFHIYRHNYRKAGTVMFEYGMRLGREVRTLRGLEKQGNCYLAALNCLRLIRPEYAWIVQPVSGAVYDRPGASPKRNHDGECTAAPTNRQIEILELEDLEKECSLARIRLTLAQHDPSAVAVAGSSSAEEMVTLLVQAGLFDTAISLCQTFKLPLTPVFEGLAFKCIKLQFGGEAAQAEAWAWLAANQLSSVITTKESSATDEAWRLLSTYLERYKVQNNLYHHCVINKLLSHGVPLPNWLINSYKKVDAAELLRLYLNYDLLEEAVDLVSEYVDAVLGKGHQYFGIEFPLSATAPMVWLPYSSIDQLLQALGENSANSHNIALSQKILDKLEDYQQKVDKATRDLLYRRTL

Target ORF information:

RefSeq Version	NM_015231.2
Organism	Homo sapiens(human)
Definition	Homo sapiens nucleoporin 160 (NUP160), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015231.2

ORF Insert Sequence:

ATGCTTCACC TGTCCGCAGC TCCGCCCGCC CCACCCCCGG AAGTGACGGC GACCGCGCGG 
CCCTGCCTTT GTTCCGTTGG GCGTCGCGGC GACGGCGGGA AGATGGCGGC GGCGGGAGCC 
CTGGAACGGA GCTTCGTGGA GCTAAGCGGA GCTGAGCGCG AAAGGCCGAG GCACTTTCGG 
GAATTCACAG TCTGCAGCAT TGGGACTGCA AATGCCGTGG CTGGCGCCGT AAAATACAGT 
GAAAGCGCGG GAGGCTTTTA CTACGTGGAG AGTGGCAAGT TGTTCTCCGT AACCAGAAAC 
AGGTTCATTC ATTGGAAGAC CTCTGGAGAT ACATTGGAGC TGATGGAGGA GTCACTGGAC 
ATAAATCTGT TGAATAATGC CATTCGCCTA AAATTCCAAA ATTGCAGTGT TTTACCTGGA 
GGGGTTTATG TCTCTGAGAC TCAGAATCGT GTGATAATCT TGATGTTAAC CAATCAAACA 
GTGCACAGGT TACTTTTACC ACACCCCTCC CGGATGTATA GGAGTGAGTT GGTAGTTGAC 
AGTCAGATGC AGTCAATATT CACTGACATT GGAAAAGTTG ATTTCACAGA TCCTTGCAAC 
TATCAGTTAA TTCCAGCAGT ACCTGGAATA TCTCCTAATT CCACCGCCTC TACAGCCTGG 
CTCAGCAGTG ATGGGGAGGC CCTGTTTGCC TTACCATGTG CTTCTGGGGG AATCTTTGTT 
CTTAAGCTAC CTCCTTATGA CATACCTGGT ATGGTGTCAG TCGTGGAACT GAAACAGAGT 
TCAGTAATGC AACGATTGCT TACAGGCTGG ATGCCAACAG CTATCAGGGG TGACCAGTCG 
CCTTCAGATC GTCCCCTCAG TCTTGCTGTT CATTGTGTGG AGCATGATGC CTTCATCTTT 
GCTTTGTGTC AGGATCATAA ACTACGAATG TGGTCTTACA AGGAGCAAAT GTGCCTAATG 
GTAGCTGACA TGCTGGAGTA TGTCCCTGTG AAGAAAGACC TTCGGCTTAC TGCTGGAACT 
GGACACAAAT TACGGCTTGC TTATTCCCCC ACCATGGGAC TCTACCTGGG GATATACATG 
CATGCACCAA AACGAGGACA GTTCTGCATT TTCCAGTTGG TGAGCACTGA GAGTAATCGC 
TATAGTCTCG ATCATATTTC TTCACTGTTC ACTTCTCAGG AGACACTGAT TGACTTTGCC 
TTAACTTCCA CGGATATCTG GGCCCTGTGG CATGATGCTG AGAACCAAAC AGTAGTGAAA 
TACATCAACT TTGAACATAA TGTTGCAGGT CAGTGGAATC CAGTTTTTAT GCAGCCTCTG 
CCAGAGGAAG AGATTGTCAT CAGAGATGAT CAAGACCCCA GAGAGATGTA TCTGCAAAGT 
CTTTTTACAC CAGGACAATT CACAAATGAA GCTTTATGTA AGGCTTTACA GATTTTCTGC 
CGAGGAACTG AGAGGAATTT GGATCTTTCC TGGAGTGAAC TGAAGAAAGA AGTTACTTTA 
GCTGTTGAAA ATGAGCTTCA AGGAAGTGTA ACAGAGTATG AATTCTCCCA GGAGGAGTTT 
CGAAATTTAC AACAAGAATT CTGGTGCAAG TTCTATGCCT GTTGTCTTCA GTATCAAGAA 
GCCCTCTCTC ACCCTCTTGC CCTACATTTG AATCCACACA CAAACATGGT GTGCCTGCTG 
AAAAAAGGGT ACCTGTCTTT CCTTATTCCC TCATCCTTAG TGGATCATTT GTATCTCCTG 
CCTTATGAGA ACCTTTTGAC AGAAGATGAG ACAACCATAT CTGATGATGT GGATATCGCT 
CGGGATGTCA TATGTCTTAT AAAATGCCTC CGGCTGATTG AAGAGTCAGT AACTGTGGAT 
ATGTCAGTTA TAATGGAAAT GAGTTGTTAT AACCTACAGT CTCCGGAAAA GGCTGCAGAG 
CAGATTCTGG AAGATATGAT CACTATTGAT GTAGAAAATG TGATGGAGGA TATTTGTAGT 
AAACTGCAAG AGATTAGGAA CCCAATCCAT GCAATTGGAC TACTTATACG GGAAATGGAT 
TATGAAACAG AAGTGGAAAT GGAAAAGGGA TTCAATCCAG CTCAGCCTTT GAATATTCGA 
ATGAATCTTA CCCAGCTCTA TGGTAGTAAC ACAGCAGGGT ATATTGTGTG CAGAGGGGTG 
CATAAAATCG CCAGTACTCG TTTCCTGATC TGCAGAGATC TTTTGATCTT ACAGCAGCTG 
TTAATGAGGC TTGGAGATGC TGTGATTTGG GGAACTGGTC AGCTCTTTCA AGCTCAGCAA 
GACCTACTAC ATCGAACAGC TCCCCTACTC TTATCTTATT ACCTCATTAA ATGGGGAAGT 
GAGTGCTTGG CAACTGATGT TCCACTTGAC ACACTGGAGT CTAATCTCCA ACACTTATCA 
GTACTGGAAT TAACAGACTC TGGTGCTTTA ATGGCAAATA GGTTTGTATC TAGTCCTCAG 
ACTATTGTGG AGTTATTCTT CCAAGAAGTT GCAAGAAAAC ACATTATATC TCACCTCTTC 
TCTCAGCCAA AGGCACCTCT GAGCCAAACT GGATTGAATT GGCCTGAAAT GATTACTGCA 
ATTACCAGTT ATTTATTGCA GCTTTTATGG CCTAGCAATC CTGGTTGTCT CTTTCTAGAA 
TGTTTGATGG GAAATTGCCA ATATGTACAA TTGCAGGATT ATATTCAACT GCTACATCCC 
TGGTGTCAAG TCAATGTTGG TTCCTGTCGA TTTATGCTGG GAAGGTGTTA CCTAGTTACA 
GGAGAAGGAC AGAAGGCTCT GGAATGTTTT TGTCAGGCAG CATCTGAAGT AGGCAAAGAG 
GAATTCTTGG ATCGCTTGAT TCGCTCAGAG GATGGGGAGA TCGTGTCTAC CCCCAGGCTG 
CAGTATTATG ACAAGGTTTT ACGACTACTA GATGTCATTG GTTTGCCTGA ACTGGTTATT 
CAGTTGGCTA CATCAGCCAT AACTGAAGCA GGTGATGACT GGAAAAGTCA GGCTACTCTA 
AGGACATGTA TTTTCAAACA TCATTTGGAT TTGGGTCACA ATAGCCAAGC ATATGAAGCC 
TTAACCCAAA TTCCTGATTC CAGCAGGCAA TTAGATTGTT TACGGCAGTT GGTGGTAGTT 
CTTTGTGAAC GCTCACAGCT ACAGGATCTT GTAGAGTTTC CCTATGTGAA TCTGCATAAT 
GAGGTTGTGG GAATAATTGA GTCACGTGCT AGAGCTGTGG ACCTTATGAC TCACAATTAC 
TATGAACTTC TGTATGCCTT TCACATCTAT CGCCACAATT ACCGCAAGGC TGGCACAGTG 
ATGTTTGAGT ATGGAATGCG GCTTGGCAGA GAAGTTCGAA CTCTCCGGGG ACTTGAGAAA 
CAAGGCAACT GTTATCTGGC TGCTCTCAAT TGTTTACGAC TTATTCGTCC AGAATATGCG 
TGGATTGTGC AGCCAGTGTC TGGTGCAGTG TATGATCGCC CTGGAGCATC CCCTAAGAGG 
AATCATGATG GAGAATGCAC AGCTGCCCCC ACAAATCGAC AAATTGAAAT CCTGGAACTG 
GAAGATCTGG AGAAAGAGTG TTCCTTGGCT CGCATCCGCC TCACTTTGGC TCAGCATGAT 
CCATCAGCGG TTGCAGTTGC TGGAAGTTCA TCAGCAGAGG AAATGGTCAC TCTCTTGGTT 
CAGGCGGGCC TCTTTGACAC TGCCATATCA CTCTGTCAGA CTTTTAAGCT TCCCTTAACG 
CCAGTCTTTG AAGGGCTTGC CTTCAAATGC ATCAAATTGC AATTTGGAGG AGAGGCAGCA 
CAAGCAGAAG CCTGGGCCTG GCTAGCAGCC AATCAGCTCT CATCTGTCAT CACTACTAAG 
GAGTCTAGTG CTACAGATGA AGCATGGCGA CTATTATCCA CTTACCTGGA GAGGTACAAA 
GTCCAGAATA ACTTGTATCA CCACTGTGTA ATCAACAAGC TCTTGTCTCA TGGAGTGCCT 
CTGCCTAATT GGCTTATAAA CAGTTACAAG AAGGTTGATG CTGCTGAATT GCTTCGTTTA 
TACTTAAACT ATGACCTTTT AGAAGAAGCT GTGGATTTGG TGTCAGAATA TGTGGATGCT 
GTATTGGGAA AAGGACATCA ATACTTCGGA ATTGAGTTTC CACTGTCCGC AACAGCCCCA 
ATGGTGTGGC TTCCATACTC CTCTATTGAT CAGCTTCTCC AAGCTCTGGG AGAGAACAGT 
GCCAACAGTC ACAACATCGC ACTGTCCCAG AAAATACTTG ACAAATTGGA GGACTACCAG 
CAAAAAGTTG ATAAGGCAAC ACGGGATTTA TTATATCGTC GGACCTTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

NUP160-SLC43A3 is a novel recurrent fusion oncogene in angiosarcoma.
Cancer research75(21)4458-65(2015 Nov)
Shimozono N,Jinnin M,Masuzawa M,Masuzawa M,Wang Z,Hirano A,Tomizawa Y,Etoh-Kira T,Kajihara I,Harada M,Fukushima S,Ihn H

Intranuclear dynamics of the Nup107-160 complex.
Molecular biology of the cell26(12)2343-56(2015 Jun)
Morchoisne-Bolhy S,Geoffroy MC,Bouhlel IB,Alves A,Audug? N,Baudin X,Van Bortle K,Powers MA,Doye V

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma.
Nature genetics46(10)1126-1130(2014 Oct)
Hysi PG,Cheng CY,Springelkamp H,Macgregor S,Bailey JNC,Wojciechowski R,Vitart V,Nag A,Hewitt AW,H?hn R,Venturini C,Mirshahi A,Ramdas WD,Thorleifsson G,Vithana E,Khor CC,Stefansson AB,Liao J,Haines JL,Amin N,Wang YX,Wild PS,Ozel AB,Li JZ,Fleck BW,Zeller T,Staffieri SE,Teo YY,Cuellar-Partida G,Luo X,Allingham RR,Richards JE,Senft A,Karssen LC,Zheng Y,Bellenguez C,Xu L,Iglesias AI,Wilson JF,Kang JH,van Leeuwen EM,Jonsson V,Thorsteinsdottir U,Despriet DDG,Ennis S,Moroi SE,Martin NG,Jansonius NM,Yazar S,Tai ES,Amouyel P,Kirwan J,van Koolwijk LME,Hauser MA,Jonasson F,Leo P,Loomis SJ,Fogarty R,Rivadeneira F,Kearns L,Lackner KJ,de Jong PTVM,Simpson CL,Pennell CE,Oostra BA,Uitterlinden AG,Saw SM,Lotery AJ,Bailey-Wilson JE,Hofman A,Vingerling JR,Maubaret C,Pfeiffer N,Wolfs RCW,Lemij HG,Young TL,Pasquale LR,Delcourt C,Spector TD,Klaver CCW,Small KS,Burdon KP,Stefansson K,Wong TY,,,,Viswanathan A,Mackey DA,Craig JE,Wiggs JL,van Duijn CM,Hammond CJ,Aung T

The SUMO-specific isopeptidase SENP2 associates dynamically with nuclear pore complexes through interactions with karyopherins and the Nup107-160 nucleoporin subcomplex.
Molecular biology of the cell22(24)4868-82(2011 Dec)
Goeres J,Chan PK,Mukhopadhyay D,Zhang H,Raught B,Matunis MJ

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NUP160 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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