PDS5A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PDS5A
Entrez Gene ID	23244
Full Name	PDS5 cohesin associated factor A
Synonyms	PIG54,SCC-112,SCC112
General protein information	Preferred Names PDS5 cohesin associated factor A Names sister chromatid cohesion protein PDS5 homolog A PDS5, regulator of cohesion maintenance, homolog A cell proliferation-inducing gene 54 protein sister chromatid cohesion protein 112
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4p14
Summary	The protein encoded by this gene binds to the cohesin complex and associates with chromatin through most of the cell cycle. The encoded protein may play a role in regulating sister chromatid cohesion during mitosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].
Disorder MIM:	613200

mRNA and Protein(s)

mRNA	Protein	Name
NM_001100400.1	NP_001093870.1	sister chromatid cohesion protein PDS5 homolog A isoform 3
NM_001100399.2	NP_001093869.1	sister chromatid cohesion protein PDS5 homolog A isoform 1
XM_011513672.2	XP_011511974.1	sister chromatid cohesion protein PDS5 homolog A isoform X1
NM_001100399.1	NP_001093869.1	sister chromatid cohesion protein PDS5 homolog A isoform 1
XM_017007928.1	XP_016863417.1	sister chromatid cohesion protein PDS5 homolog A isoform X1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	pds5a	NP_957286.2
Arabidopsis thaliana (thale cress)	AT5G47690	NP_001119390.1
Homo sapiens (human)	PDS5A	NP_001093869.1
Canis lupus familiaris (dog)	PDS5A	XP_005618670.1
Mus musculus (house mouse)	Pds5a	NP_001074790.1
Xenopus tropicalis (tropical clawed frog)	LOC100490474	XP_004910976.1
Gallus gallus (chicken)	PDS5A	NP_001012598.1
Oryza sativa (rice)	Os06g0286351	NP_001174723.1
Bos taurus (cattle)	PDS5A	XP_002688275.2
Rattus norvegicus (Norway rat)	Pds5a	NP_001077093.1

Gene Ontology
Bibliography

Related articles in PubMed

Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins.
Wutz G, V?rnai C, Nagasaka K, Cisneros DA, Stocsits RR, Tang W, Schoenfelder S, Jessberger G, Muhar M, Hossain MJ, Walther N, Koch B, Kueblbeck M, Ellenberg J, Zuber J, Fraser P, Peters JM
The EMBO journal36(24)3573-3599(2017 12)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Higher Order Chromatin Modulator Cohesin SA1 Is an Early Biomarker for Colon Carcinogenesis: Race-Specific Implications.
Wali RK, Momi N, Dela Cruz M, Calderwood AH, Stypula-Cyrus Y, Almassalha L, Chhaparia A, Weber CR, Radosevich A, Tiwari AK, Latif B, Backman V, Roy HK
Cancer prevention research (Philadelphia, Pa.)9(11)844-854(2016 Nov)

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M
Cell163(3)712-23(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results show that cohesin has an essential genome-wide function in mediating long-range chromatin interactions and support the hypothesis that cohesin creates these by loop extrusion, until it is delayed by CTCF in a manner dependent on PDS5 proteins, or until it is released from DNA by WAPL.
Title: Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins.

These results provide the first evidence indicating a tumor suppressor role of SA1 in early colon carcinogenesis
Title: Higher Order Chromatin Modulator Cohesin SA1 Is an Early Biomarker for Colon Carcinogenesis: Race-Specific Implications.

By interacting with a unique domain of Esco1, Pds5 recruits Esco1 to chromatin-bound cohesin complexes to form cohesion.
Title: Esco1 Acetylates Cohesin via a Mechanism Different from That of Esco2.

The data show a downregulation of proliferation-associated host gene PDS5A and suggest a role of PDS5A in HIV-1-induced cellular pathogenesis but not viral replication.
Title: HIV-1 infection suppresses expression of host cell cycle-associated gene PDS5A.

Data show that the siRNA-mediated knockdown of Pds5A affects sister chromatid cohesion but does not influence mitotic checkpoint function or the proliferation and survival of glioblastoma multiforme cells.
Title: The cohesin-interacting protein, precocious dissociation of sisters 5A/sister chromatid cohesion protein 112, is up-regulated in human astrocytic tumors.

The following PDS5A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PDS5A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu06080	NM_001100400.1 Latest version!	Homo sapiens PDS5 cohesin associated factor A (PDS5A), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu19510	NM_001100399.2 Latest version!	Homo sapiens PDS5 cohesin associated factor A (PDS5A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$727.30 $1039.00
OHu19510	XM_017007928.1 Latest version!	Homo sapiens PDS5 cohesin associated factor A (PDS5A), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$727.30 $1039.00
OHu19510	XM_011513672.2 Latest version!	Homo sapiens PDS5 cohesin associated factor A (PDS5A), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$727.30 $1039.00
View Old Accession Versions >>
OHu19510	NM_001100399.1	Homo sapiens PDS5 cohesin associated factor A (PDS5A), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$727.30 $1039.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PDS5A ( NM_001100400.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093870.1 Homo sapiens PDS5 cohesin associated factor A (PDS5A), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu06080
Clone ID Related Accession (Same CDS sequence)	NM_001100400.1
Accession Version	NM_001100400.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1803bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	sister chromatid cohesion protein PDS5 homolog A isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC041361.1, AC098591.4 and CA412233.1. Transcript Variant: This variant (3) differs in the 3' UTR and lacks several exons in the 3' coding region, compared to variant 1. The resulting protein (isoform 3) has a distinct C-terminus and is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC041361.1, SRR1660805.189098.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACTTCA CCGCGCAGCC CAAGCCTGCC ACTGCCCTCT GTGGCGTCGT GAGTGCCGAC 
GGGAAGATCG CTTACCCTCC GGGGGTAAAA GAGATCACCG ACAAGATCAC CACGGACGAG 
ATGATCAAAC GCCTGAAGAT GGTAGTGAAA ACCTTTATGG ATATGGATCA GGACTCAGAA 
GATGAAAAAC AGCAGTATCT CCCACTAGCC TTGCATCTTG CATCTGAATT CTTCCTCAGG 
AACCCCAATA AAGATGTGCG TCTCCTTGTA GCATGTTGTT TGGCTGATAT CTTTCGTATC 
TATGCCCCAG AAGCTCCATA TACTTCCCAT GATAAACTTA AGGACATATT TTTGTTTATT 
ACCAGACAAT TAAAAGGTTT GGAGGATACA AAGAGTCCAC AGTTTAATAG ATACTTTTAT 
TTATTAGAGA ATTTAGCTTG GGTTAAATCA TATAACATCT GCTTTGAATT GGAAGATTGC 
AATGAAATTT TTATTCAGCT TTTTAGAACT CTCTTCTCAG TGATCAACAA TAGCCACAAT 
AAGAAGGTAC AAATGCACAT GCTAGATTTG ATGAGTTCTA TCATCATGGA AGGTGATGGA 
GTTACTCAAG AATTATTGGA CTCCATTCTT ATTAACCTCA TTCCTGCACA TAAGAACTTA 
AATAAACAGT CCTTTGACCT TGCAAAAGTG CTATTGAAAA GAACAGTCCA GACTATTGAG 
GCATGCATTG CTAATTTTTT CAATCAAGTC CTGGTGCTGG GAAGATCATC AGTAAGTGAT 
TTGTCAGAAC ATGTATTTGA TCTGATTCAG GAACTTTTTG CTATAGATCC TCATTTATTA 
TTATCCGTCA TGCCACAGCT TGAATTCAAA CTAAAGAGCA ATGATGGAGA AGAGCGATTA 
GCTGTTGTTC GACTTCTAGC TAAATTGTTT GGCTCCAAAG ATTCTGATTT GGCAACACAG 
AATCGTCCTC TTTGGCAATG TTTTCTTGGA CGATTTAATG ATATTCATGT TCCTGTGAGA 
TTAGAAAGTG TGAAATTTGC CAGTCATTGT TTAATGAATC ACCCAGATTT AGCGAAGGAT 
CTCACAGAAT ATTTAAAGGT TAGATCACAT GATCCAGAAG AAGCTATTCG TCATGATGTC 
ATTGTTACTA TAATAACAGC TGCCAAGAGG GACCTGGCCT TAGTAAATGA TCAGCTGCTT 
GGCTTTGTAA GGGAAAGAAC ACTGGATAAA CGGTGGCGAG TAAGAAAAGA AGCTATGATG 
GGTCTGGCTC AGCTTTATAA GAAATACTGT CTTCATGGTG AAGCAGGAAA GGAAGCTGCA 
GAGAAAGTCA GCTGGATAAA GGACAAACTT CTGCATATTT ATTATCAGAA CAGCATTGAC 
GACAAACTGT TGGTAGAGAA AATCTTTGCT CAGTATCTTG TCCCCCACAA CCTGGAAACA 
GAAGAGAGAA TGAAATGCTT ATATTACTTA TATGCTAGTT TGGATCCAAA TGCTGTAAAA 
GCTCTCAACG AAATGTGGAA GTGTCAGAAC ATGCTTCGGA GCCATGTACG CGAACTATTG 
GATTTGCACA AGCAGCCTAC ATCAGAGGCT AACTGTTCTG CCATGTTTGG AAAACTGATG 
ACCATAGCAA AGAATTTGCC TGACCCCGGG AAAGCACAAG ATTTTGTGAA GAAATTTAAC 
CAGGTTCTCG GCGATGATGA GAAACTTCGG TCTCAGTTGG AGTTATTAAT TAGCCCAACC 
TGTTCTTGCA AACAAGCAGA TATTTGTGTG GTTAGTAAAT CATACTTCAC ACTTTTTCTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093870.1
CDS	541..2343
Translation	MDFTAQPKPATALCGVVSADGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADICVVSKSYFTLFL

Target ORF information:

RefSeq Version	NM_001100400.1
Organism	Homo sapiens(human)
Definition	Homo sapiens PDS5 cohesin associated factor A (PDS5A), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100400.1

ORF Insert Sequence:

ATGGACTTCA CCGCGCAGCC CAAGCCTGCC ACTGCCCTCT GTGGCGTCGT GAGTGCCGAC 
GGGAAGATCG CTTACCCTCC GGGGGTAAAA GAGATCACCG ACAAGATCAC CACGGACGAG 
ATGATCAAAC GCCTGAAGAT GGTAGTGAAA ACCTTTATGG ATATGGATCA GGACTCAGAA 
GATGAAAAAC AGCAGTATCT CCCACTAGCC TTGCATCTTG CATCTGAATT CTTCCTCAGG 
AACCCCAATA AAGATGTGCG TCTCCTTGTA GCATGTTGTT TGGCTGATAT CTTTCGTATC 
TATGCCCCAG AAGCTCCATA TACTTCCCAT GATAAACTTA AGGACATATT TTTGTTTATT 
ACCAGACAAT TAAAAGGTTT GGAGGATACA AAGAGTCCAC AGTTTAATAG ATACTTTTAT 
TTATTAGAGA ATTTAGCTTG GGTTAAATCA TATAACATCT GCTTTGAATT GGAAGATTGC 
AATGAAATTT TTATTCAGCT TTTTAGAACT CTCTTCTCAG TGATCAACAA TAGCCACAAT 
AAGAAGGTAC AAATGCACAT GCTAGATTTG ATGAGTTCTA TCATCATGGA AGGTGATGGA 
GTTACTCAAG AATTATTGGA CTCCATTCTT ATTAACCTCA TTCCTGCACA TAAGAACTTA 
AATAAACAGT CCTTTGACCT TGCAAAAGTG CTATTGAAAA GAACAGTCCA GACTATTGAG 
GCATGCATTG CTAATTTTTT CAATCAAGTC CTGGTGCTGG GAAGATCATC AGTAAGTGAT 
TTGTCAGAAC ATGTATTTGA TCTGATTCAG GAACTTTTTG CTATAGATCC TCATTTATTA 
TTATCCGTCA TGCCACAGCT TGAATTCAAA CTAAAGAGCA ATGATGGAGA AGAGCGATTA 
GCTGTTGTTC GACTTCTAGC TAAATTGTTT GGCTCCAAAG ATTCTGATTT GGCAACACAG 
AATCGTCCTC TTTGGCAATG TTTTCTTGGA CGATTTAATG ATATTCATGT TCCTGTGAGA 
TTAGAAAGTG TGAAATTTGC CAGTCATTGT TTAATGAATC ACCCAGATTT AGCGAAGGAT 
CTCACAGAAT ATTTAAAGGT TAGATCACAT GATCCAGAAG AAGCTATTCG TCATGATGTC 
ATTGTTACTA TAATAACAGC TGCCAAGAGG GACCTGGCCT TAGTAAATGA TCAGCTGCTT 
GGCTTTGTAA GGGAAAGAAC ACTGGATAAA CGGTGGCGAG TAAGAAAAGA AGCTATGATG 
GGTCTGGCTC AGCTTTATAA GAAATACTGT CTTCATGGTG AAGCAGGAAA GGAAGCTGCA 
GAGAAAGTCA GCTGGATAAA GGACAAACTT CTGCATATTT ATTATCAGAA CAGCATTGAC 
GACAAACTGT TGGTAGAGAA AATCTTTGCT CAGTATCTTG TCCCCCACAA CCTGGAAACA 
GAAGAGAGAA TGAAATGCTT ATATTACTTA TATGCTAGTT TGGATCCAAA TGCTGTAAAA 
GCTCTCAACG AAATGTGGAA GTGTCAGAAC ATGCTTCGGA GCCATGTACG CGAACTATTG 
GATTTGCACA AGCAGCCTAC ATCAGAGGCT AACTGTTCTG CCATGTTTGG AAAACTGATG 
ACCATAGCAA AGAATTTGCC TGACCCCGGG AAAGCACAAG ATTTTGTGAA GAAATTTAAC 
CAGGTTCTCG GCGATGATGA GAAACTTCGG TCTCAGTTGG AGTTATTAAT TAGCCCAACC 
TGTTCTTGCA AACAAGCAGA TATTTGTGTG GTTAGTAAAT CATACTTCAC ACTTTTTCTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PDS5A ( NM_001100399.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093869.1 Homo sapiens PDS5 cohesin associated factor A (PDS5A), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19510
Clone ID Related Accession (Same CDS sequence)	NM_001100399.2 , XM_011513672.2 , NM_001100399.1 , XM_017007928.1
Accession Version	NM_001100399.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	sister chromatid cohesion protein PDS5 homolog A isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC041361.1, AC098591.4 and BC114218.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_001100399.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC114218.1, AB621803.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000303538.13/ ENSP00000303427.8 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGACTTCA CCGCGCAGCC CAAGCCTGCC ACTGCCCTCT GTGGCGTCGT GAGTGCCGAC 
GGGAAGATCG CTTACCCTCC GGGGGTAAAA GAGATCACCG ACAAGATCAC CACGGACGAG 
ATGATCAAAC GCCTGAAGAT GGTAGTGAAA ACCTTTATGG ATATGGATCA GGACTCAGAA 
GATGAAAAAC AGCAGTATCT CCCACTAGCC TTGCATCTTG CATCTGAATT CTTCCTCAGG 
AACCCCAATA AAGATGTGCG TCTCCTTGTA GCATGTTGTT TGGCTGATAT CTTTCGTATC 
TATGCCCCAG AAGCTCCATA TACTTCCCAT GATAAACTTA AGGACATATT TTTGTTTATT 
ACCAGACAAT TAAAAGGTTT GGAGGATACA AAGAGTCCAC AGTTTAATAG ATACTTTTAT 
TTATTAGAGA ATTTAGCTTG GGTTAAATCA TATAACATCT GCTTTGAATT GGAAGATTGC 
AATGAAATTT TTATTCAGCT TTTTAGAACT CTCTTCTCAG TGATCAACAA TAGCCACAAT 
AAGAAGGTAC AAATGCACAT GCTAGATTTG ATGAGTTCTA TCATCATGGA AGGTGATGGA 
GTTACTCAAG AATTATTGGA CTCCATTCTT ATTAACCTCA TTCCTGCACA TAAGAACTTA 
AATAAACAGT CCTTTGACCT TGCAAAAGTG CTATTGAAAA GAACAGTCCA GACTATTGAG 
GCATGCATTG CTAATTTTTT CAATCAAGTC CTGGTGCTGG GAAGATCATC AGTAAGTGAT 
TTGTCAGAAC ATGTATTTGA TCTGATTCAG GAACTTTTTG CTATAGATCC TCATTTATTA 
TTATCCGTCA TGCCACAGCT TGAATTCAAA CTAAAGAGCA ATGATGGAGA AGAGCGATTA 
GCTGTTGTTC GACTTCTAGC TAAATTGTTT GGCTCCAAAG ATTCTGATTT GGCAACACAG 
AATCGTCCTC TTTGGCAATG TTTTCTTGGA CGATTTAATG ATATTCATGT TCCTGTGAGA 
TTAGAAAGTG TGAAATTTGC CAGTCATTGT TTAATGAATC ACCCAGATTT AGCGAAGGAT 
CTCACAGAAT ATTTAAAGGT TAGATCACAT GATCCAGAAG AAGCTATTCG TCATGATGTC 
ATTGTTACTA TAATAACAGC TGCCAAGAGG GACCTGGCCT TAGTAAATGA TCAGCTGCTT 
GGCTTTGTAA GGGAAAGAAC ACTGGATAAA CGGTGGCGAG TAAGAAAAGA AGCTATGATG 
GGTCTGGCTC AGCTTTATAA GAAATACTGT CTTCATGGTG AAGCAGGAAA GGAAGCTGCA 
GAGAAAGTCA GCTGGATAAA GGACAAACTT CTGCATATTT ATTATCAGAA CAGCATTGAC 
GACAAACTGT TGGTAGAGAA AATCTTTGCT CAGTATCTTG TCCCCCACAA CCTGGAAACA 
GAAGAGAGAA TGAAATGCTT ATATTACTTA TATGCTAGTT TGGATCCAAA TGCTGTAAAA 
GCTCTCAACG AAATGTGGAA GTGTCAGAAC ATGCTTCGGA GCCATGTACG CGAACTATTG 
GATTTGCACA AGCAGCCTAC ATCAGAGGCT AACTGTTCTG CCATGTTTGG AAAACTGATG 
ACCATAGCAA AGAATTTGCC TGACCCCGGG AAAGCACAAG ATTTTGTGAA GAAATTTAAC 
CAGGTTCTCG GCGATGATGA GAAACTTCGG TCTCAGTTGG AGTTATTAAT TAGCCCAACC 
TGTTCTTGCA AACAAGCAGA TATTTGTGTG AGAGAAATAG CCCGGAAACT TGCAAATCCT 
AAGCAACCAA CAAATCCTTT TCTAGAGATG GTCAAATTTC TGTTGGAAAG AATCGCACCT 
GTGCACATTG ATTCAGAAGC CATAAGTGCA CTAGTGAAAT TGATGAATAA GTCAATAGAG 
GGGACAGCAG ATGATGAAGA GGAGGGTGTA AGTCCAGATA CAGCTATCCG TTCAGGACTT 
GAACTTCTTA AGGTTCTGTC TTTTACACAT CCTACCTCGT TCCACTCTGC AGAGACATAT 
GAGTCCTTGT TACAGTGCCT AAGAATGGAG GATGACAAGG TAGCAGAAGC TGCTATTCAA 
ATTTTTAGAA ATACAGGTCA CAAAATAGAA ACAGACCTTC CCCAGATACG ATCGACCTTA 
ATTCCCATTT TACATCAAAA AGCAAAGAGG GGTACTCCAC ACCAAGCAAA ACAGGCTGTG 
CACTGTATAC ACGCCATATT CACAAATAAA GAAGTCCAGC TTGCACAGAT TTTTGAGCCA 
CTCAGTAGGA GTCTGAATGC TGATGTGCCA GAACAACTTA TAACTCCATT AGTTTCATTG 
GGCCACATTT CTATGTTAGC ACCAGATCAG TTTGCTTCCC CAATGAAATC TGTAGTAGCA 
AATTTTATTG TGAAAGATCT GCTAATGAAT GACAGGTCAA CAGGTGAAAA GAATGGAAAA 
CTGTGGTCTC CAGATGAAGA GGTTTCCCCT GAAGTACTAG CAAAGGTACA GGCAATTAAA 
CTTCTGGTAA GGTGGCTGTT GGGTATGAAA AACAACCAGT CTAAATCTGC CAATTCAACC 
CTTCGGTTAT TATCAGCGAT GTTGGTTAGT GAGGGTGACC TGACAGAGCA AAAGAGGATC 
AGTAAATCTG ATATGTCTCG CTTGCGATTA GCTGCTGGTA GTGCCATAAT GAAGCTTGCT 
CAGGAACCTT GTTACCATGA AATTATTACC CCAGAACAGT TTCAGCTCTG TGCACTTGTT 
ATTAATGATG AGTGTTACCA AGTAAGGCAG ATATTTGCTC AGAAGCTGCA TAAGGCACTT 
GTGAAGTTAC TGCTCCCATT GGAGTATATG GCGATCTTTG CCTTGTGTGC CAAAGATCCT 
GTGAAGGAGA GAAGAGCACA CGCACGACAA TGTTTACTGA AAAATATCAG TATACGCAGG 
GAATACATTA AGCAGAATCC TATGGCTACT GAGAAATTAT TATCACTGTT GCCTGAATAT 
GTAGTTCCAT ACATGATTCA CCTGCTAGCC CATGATCCAG ATTTTACAAG ATCACAAGAT 
GTTGATCAGC TTCGTGATAT CAAAGAGTGC CTATGGTTCA TGCTTGAAGT TTTAATGACA 
AAGAATGAAA ACAATAGCCA TGCCTTTATG AAGAAGATGG CAGAGAACAT CAAGTTAACC 
AGAGATGCCC AGTCTCCAGA TGAATCCAAG ACAAATGAAA AACTGTATAC AGTATGTGAT 
GTGGCTCTCT GTGTTATAAA TAGTAAAAGT GCTTTGTGCA ATGCAGATTC ACCAAAGGAC 
CCAGTCCTCC CAATGAAATT TTTTACACAA CCTGAAAAGG ACTTCTGTAA CGATAAGAGT 
TATATTTCAG AAGAGACAAG AGTACTTCTG TTAACAGGAA AGCCAAAGCC TGCTGGAGTA 
CTAGGTGCAG TAAATAAGCC TTTATCAGCA ACGGGAAGGA AACCCTATGT TAGAAGCACT 
GGCACTGAGA CTGGAAGCAA TATTAATGTA AATTCAGAGC TGAACCCTTC AACCGGAAAT 
CGATCAAGGG AACAGAGTTC AGAGGCAGCA GAAACTGGAG TTAGTGAAAA TGAAGAGAAC 
CCTGTGAGGA TTATTTCAGT CACACCTGTA AAGAATATTG ACCCAGTAAA GAATAAGGAA 
ATTAATTCTG ATCAGGCTAC CCAGGGCAAC ATCAGCAGTG ACCGAGGAAA GAAAAGAACA 
GTAACAGCAG CTGGTGCAGA GAATATCCAA CAAAAAACAG ATGAGAAAGT AGATGAATCG 
GGACCTCCCG CCCCTTCCAA ACCCAGGAGA GGACGTCGAC CCAAGTCTGA ATCTCAGGGC 
AATGCTACCA AAAATGATGA TCTAAATAAA CCTATTAACA AGGGAAGGAA GAGAGCTGCA 
GTGGGTCAGG AGAGCCCTGG GGGTTTGGAA GCAGGTAATG CCAAAGCACC CAAACTGCAA 
GATTTAGCCA AAAAGGCAGC ACCAGCAGAA AGACAAATTG ACTTACAAAG GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093869.1
CDS	496..4509
Translation	MDFTAQPKPATALCGVVSADGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADICVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDTAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFTNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVQAIKLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMATEKLLSLLPEYVVPYMIHLLAHDPDFTRSQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTRDAQSPDESKTNEKLYTVCDVALCVINSKSALCNADSPKDPVLPMKFFTQPEKDFCNDKSYISEETRVLLLTGKPKPAGVLGAVNKPLSATGRKPYVRSTGTETGSNINVNSELNPSTGNRSREQSSEAAETGVSENEENPVRIISVTPVKNIDPVKNKEINSDQATQGNISSDRGKKRTVTAAGAENIQQKTDEKVDESGPPAPSKPRRGRRPKSESQGNATKNDDLNKPINKGRKRAAVGQESPGGLEAGNAKAPKLQDLAKKAAPAERQIDLQR

Target ORF information:

RefSeq Version	NM_001100399.2
Organism	Homo sapiens(human)
Definition	Homo sapiens PDS5 cohesin associated factor A (PDS5A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100399.2

ORF Insert Sequence:

ATGGACTTCA CCGCGCAGCC CAAGCCTGCC ACTGCCCTCT GTGGCGTCGT GAGTGCCGAC 
GGGAAGATCG CTTACCCTCC GGGGGTAAAA GAGATCACCG ACAAGATCAC CACGGACGAG 
ATGATCAAAC GCCTGAAGAT GGTAGTGAAA ACCTTTATGG ATATGGATCA GGACTCAGAA 
GATGAAAAAC AGCAGTATCT CCCACTAGCC TTGCATCTTG CATCTGAATT CTTCCTCAGG 
AACCCCAATA AAGATGTGCG TCTCCTTGTA GCATGTTGTT TGGCTGATAT CTTTCGTATC 
TATGCCCCAG AAGCTCCATA TACTTCCCAT GATAAACTTA AGGACATATT TTTGTTTATT 
ACCAGACAAT TAAAAGGTTT GGAGGATACA AAGAGTCCAC AGTTTAATAG ATACTTTTAT 
TTATTAGAGA ATTTAGCTTG GGTTAAATCA TATAACATCT GCTTTGAATT GGAAGATTGC 
AATGAAATTT TTATTCAGCT TTTTAGAACT CTCTTCTCAG TGATCAACAA TAGCCACAAT 
AAGAAGGTAC AAATGCACAT GCTAGATTTG ATGAGTTCTA TCATCATGGA AGGTGATGGA 
GTTACTCAAG AATTATTGGA CTCCATTCTT ATTAACCTCA TTCCTGCACA TAAGAACTTA 
AATAAACAGT CCTTTGACCT TGCAAAAGTG CTATTGAAAA GAACAGTCCA GACTATTGAG 
GCATGCATTG CTAATTTTTT CAATCAAGTC CTGGTGCTGG GAAGATCATC AGTAAGTGAT 
TTGTCAGAAC ATGTATTTGA TCTGATTCAG GAACTTTTTG CTATAGATCC TCATTTATTA 
TTATCCGTCA TGCCACAGCT TGAATTCAAA CTAAAGAGCA ATGATGGAGA AGAGCGATTA 
GCTGTTGTTC GACTTCTAGC TAAATTGTTT GGCTCCAAAG ATTCTGATTT GGCAACACAG 
AATCGTCCTC TTTGGCAATG TTTTCTTGGA CGATTTAATG ATATTCATGT TCCTGTGAGA 
TTAGAAAGTG TGAAATTTGC CAGTCATTGT TTAATGAATC ACCCAGATTT AGCGAAGGAT 
CTCACAGAAT ATTTAAAGGT TAGATCACAT GATCCAGAAG AAGCTATTCG TCATGATGTC 
ATTGTTACTA TAATAACAGC TGCCAAGAGG GACCTGGCCT TAGTAAATGA TCAGCTGCTT 
GGCTTTGTAA GGGAAAGAAC ACTGGATAAA CGGTGGCGAG TAAGAAAAGA AGCTATGATG 
GGTCTGGCTC AGCTTTATAA GAAATACTGT CTTCATGGTG AAGCAGGAAA GGAAGCTGCA 
GAGAAAGTCA GCTGGATAAA GGACAAACTT CTGCATATTT ATTATCAGAA CAGCATTGAC 
GACAAACTGT TGGTAGAGAA AATCTTTGCT CAGTATCTTG TCCCCCACAA CCTGGAAACA 
GAAGAGAGAA TGAAATGCTT ATATTACTTA TATGCTAGTT TGGATCCAAA TGCTGTAAAA 
GCTCTCAACG AAATGTGGAA GTGTCAGAAC ATGCTTCGGA GCCATGTACG CGAACTATTG 
GATTTGCACA AGCAGCCTAC ATCAGAGGCT AACTGTTCTG CCATGTTTGG AAAACTGATG 
ACCATAGCAA AGAATTTGCC TGACCCCGGG AAAGCACAAG ATTTTGTGAA GAAATTTAAC 
CAGGTTCTCG GCGATGATGA GAAACTTCGG TCTCAGTTGG AGTTATTAAT TAGCCCAACC 
TGTTCTTGCA AACAAGCAGA TATTTGTGTG AGAGAAATAG CCCGGAAACT TGCAAATCCT 
AAGCAACCAA CAAATCCTTT TCTAGAGATG GTCAAATTTC TGTTGGAAAG AATCGCACCT 
GTGCACATTG ATTCAGAAGC CATAAGTGCA CTAGTGAAAT TGATGAATAA GTCAATAGAG 
GGGACAGCAG ATGATGAAGA GGAGGGTGTA AGTCCAGATA CAGCTATCCG TTCAGGACTT 
GAACTTCTTA AGGTTCTGTC TTTTACACAT CCTACCTCGT TCCACTCTGC AGAGACATAT 
GAGTCCTTGT TACAGTGCCT AAGAATGGAG GATGACAAGG TAGCAGAAGC TGCTATTCAA 
ATTTTTAGAA ATACAGGTCA CAAAATAGAA ACAGACCTTC CCCAGATACG ATCGACCTTA 
ATTCCCATTT TACATCAAAA AGCAAAGAGG GGTACTCCAC ACCAAGCAAA ACAGGCTGTG 
CACTGTATAC ACGCCATATT CACAAATAAA GAAGTCCAGC TTGCACAGAT TTTTGAGCCA 
CTCAGTAGGA GTCTGAATGC TGATGTGCCA GAACAACTTA TAACTCCATT AGTTTCATTG 
GGCCACATTT CTATGTTAGC ACCAGATCAG TTTGCTTCCC CAATGAAATC TGTAGTAGCA 
AATTTTATTG TGAAAGATCT GCTAATGAAT GACAGGTCAA CAGGTGAAAA GAATGGAAAA 
CTGTGGTCTC CAGATGAAGA GGTTTCCCCT GAAGTACTAG CAAAGGTACA GGCAATTAAA 
CTTCTGGTAA GGTGGCTGTT GGGTATGAAA AACAACCAGT CTAAATCTGC CAATTCAACC 
CTTCGGTTAT TATCAGCGAT GTTGGTTAGT GAGGGTGACC TGACAGAGCA AAAGAGGATC 
AGTAAATCTG ATATGTCTCG CTTGCGATTA GCTGCTGGTA GTGCCATAAT GAAGCTTGCT 
CAGGAACCTT GTTACCATGA AATTATTACC CCAGAACAGT TTCAGCTCTG TGCACTTGTT 
ATTAATGATG AGTGTTACCA AGTAAGGCAG ATATTTGCTC AGAAGCTGCA TAAGGCACTT 
GTGAAGTTAC TGCTCCCATT GGAGTATATG GCGATCTTTG CCTTGTGTGC CAAAGATCCT 
GTGAAGGAGA GAAGAGCACA CGCACGACAA TGTTTACTGA AAAATATCAG TATACGCAGG 
GAATACATTA AGCAGAATCC TATGGCTACT GAGAAATTAT TATCACTGTT GCCTGAATAT 
GTAGTTCCAT ACATGATTCA CCTGCTAGCC CATGATCCAG ATTTTACAAG ATCACAAGAT 
GTTGATCAGC TTCGTGATAT CAAAGAGTGC CTATGGTTCA TGCTTGAAGT TTTAATGACA 
AAGAATGAAA ACAATAGCCA TGCCTTTATG AAGAAGATGG CAGAGAACAT CAAGTTAACC 
AGAGATGCCC AGTCTCCAGA TGAATCCAAG ACAAATGAAA AACTGTATAC AGTATGTGAT 
GTGGCTCTCT GTGTTATAAA TAGTAAAAGT GCTTTGTGCA ATGCAGATTC ACCAAAGGAC 
CCAGTCCTCC CAATGAAATT TTTTACACAA CCTGAAAAGG ACTTCTGTAA CGATAAGAGT 
TATATTTCAG AAGAGACAAG AGTACTTCTG TTAACAGGAA AGCCAAAGCC TGCTGGAGTA 
CTAGGTGCAG TAAATAAGCC TTTATCAGCA ACGGGAAGGA AACCCTATGT TAGAAGCACT 
GGCACTGAGA CTGGAAGCAA TATTAATGTA AATTCAGAGC TGAACCCTTC AACCGGAAAT 
CGATCAAGGG AACAGAGTTC AGAGGCAGCA GAAACTGGAG TTAGTGAAAA TGAAGAGAAC 
CCTGTGAGGA TTATTTCAGT CACACCTGTA AAGAATATTG ACCCAGTAAA GAATAAGGAA 
ATTAATTCTG ATCAGGCTAC CCAGGGCAAC ATCAGCAGTG ACCGAGGAAA GAAAAGAACA 
GTAACAGCAG CTGGTGCAGA GAATATCCAA CAAAAAACAG ATGAGAAAGT AGATGAATCG 
GGACCTCCCG CCCCTTCCAA ACCCAGGAGA GGACGTCGAC CCAAGTCTGA ATCTCAGGGC 
AATGCTACCA AAAATGATGA TCTAAATAAA CCTATTAACA AGGGAAGGAA GAGAGCTGCA 
GTGGGTCAGG AGAGCCCTGG GGGTTTGGAA GCAGGTAATG CCAAAGCACC CAAACTGCAA 
GATTTAGCCA AAAAGGCAGC ACCAGCAGAA AGACAAATTG ACTTACAAAG GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PDS5A ( NM_001100399.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093869.1 Homo sapiens PDS5 cohesin associated factor A (PDS5A), transcript variant 1, mRNA.

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CloneID	OHu19510
Clone ID Related Accession (Same CDS sequence)	NM_001100399.2 , XM_011513672.2 , NM_001100399.1 , XM_017007928.1
Accession Version	NM_001100399.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-31
Organism	Homo sapiens(human)
Product	sister chromatid cohesion protein PDS5 homolog A isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC041361.1, AC098591.4 and BC114218.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC114218.1, AB621803.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACTTCA CCGCGCAGCC CAAGCCTGCC ACTGCCCTCT GTGGCGTCGT GAGTGCCGAC 
GGGAAGATCG CTTACCCTCC GGGGGTAAAA GAGATCACCG ACAAGATCAC CACGGACGAG 
ATGATCAAAC GCCTGAAGAT GGTAGTGAAA ACCTTTATGG ATATGGATCA GGACTCAGAA 
GATGAAAAAC AGCAGTATCT CCCACTAGCC TTGCATCTTG CATCTGAATT CTTCCTCAGG 
AACCCCAATA AAGATGTGCG TCTCCTTGTA GCATGTTGTT TGGCTGATAT CTTTCGTATC 
TATGCCCCAG AAGCTCCATA TACTTCCCAT GATAAACTTA AGGACATATT TTTGTTTATT 
ACCAGACAAT TAAAAGGTTT GGAGGATACA AAGAGTCCAC AGTTTAATAG ATACTTTTAT 
TTATTAGAGA ATTTAGCTTG GGTTAAATCA TATAACATCT GCTTTGAATT GGAAGATTGC 
AATGAAATTT TTATTCAGCT TTTTAGAACT CTCTTCTCAG TGATCAACAA TAGCCACAAT 
AAGAAGGTAC AAATGCACAT GCTAGATTTG ATGAGTTCTA TCATCATGGA AGGTGATGGA 
GTTACTCAAG AATTATTGGA CTCCATTCTT ATTAACCTCA TTCCTGCACA TAAGAACTTA 
AATAAACAGT CCTTTGACCT TGCAAAAGTG CTATTGAAAA GAACAGTCCA GACTATTGAG 
GCATGCATTG CTAATTTTTT CAATCAAGTC CTGGTGCTGG GAAGATCATC AGTAAGTGAT 
TTGTCAGAAC ATGTATTTGA TCTGATTCAG GAACTTTTTG CTATAGATCC TCATTTATTA 
TTATCCGTCA TGCCACAGCT TGAATTCAAA CTAAAGAGCA ATGATGGAGA AGAGCGATTA 
GCTGTTGTTC GACTTCTAGC TAAATTGTTT GGCTCCAAAG ATTCTGATTT GGCAACACAG 
AATCGTCCTC TTTGGCAATG TTTTCTTGGA CGATTTAATG ATATTCATGT TCCTGTGAGA 
TTAGAAAGTG TGAAATTTGC CAGTCATTGT TTAATGAATC ACCCAGATTT AGCGAAGGAT 
CTCACAGAAT ATTTAAAGGT TAGATCACAT GATCCAGAAG AAGCTATTCG TCATGATGTC 
ATTGTTACTA TAATAACAGC TGCCAAGAGG GACCTGGCCT TAGTAAATGA TCAGCTGCTT 
GGCTTTGTAA GGGAAAGAAC ACTGGATAAA CGGTGGCGAG TAAGAAAAGA AGCTATGATG 
GGTCTGGCTC AGCTTTATAA GAAATACTGT CTTCATGGTG AAGCAGGAAA GGAAGCTGCA 
GAGAAAGTCA GCTGGATAAA GGACAAACTT CTGCATATTT ATTATCAGAA CAGCATTGAC 
GACAAACTGT TGGTAGAGAA AATCTTTGCT CAGTATCTTG TCCCCCACAA CCTGGAAACA 
GAAGAGAGAA TGAAATGCTT ATATTACTTA TATGCTAGTT TGGATCCAAA TGCTGTAAAA 
GCTCTCAACG AAATGTGGAA GTGTCAGAAC ATGCTTCGGA GCCATGTACG CGAACTATTG 
GATTTGCACA AGCAGCCTAC ATCAGAGGCT AACTGTTCTG CCATGTTTGG AAAACTGATG 
ACCATAGCAA AGAATTTGCC TGACCCCGGG AAAGCACAAG ATTTTGTGAA GAAATTTAAC 
CAGGTTCTCG GCGATGATGA GAAACTTCGG TCTCAGTTGG AGTTATTAAT TAGCCCAACC 
TGTTCTTGCA AACAAGCAGA TATTTGTGTG AGAGAAATAG CCCGGAAACT TGCAAATCCT 
AAGCAACCAA CAAATCCTTT TCTAGAGATG GTCAAATTTC TGTTGGAAAG AATCGCACCT 
GTGCACATTG ATTCAGAAGC CATAAGTGCA CTAGTGAAAT TGATGAATAA GTCAATAGAG 
GGGACAGCAG ATGATGAAGA GGAGGGTGTA AGTCCAGATA CAGCTATCCG TTCAGGACTT 
GAACTTCTTA AGGTTCTGTC TTTTACACAT CCTACCTCGT TCCACTCTGC AGAGACATAT 
GAGTCCTTGT TACAGTGCCT AAGAATGGAG GATGACAAGG TAGCAGAAGC TGCTATTCAA 
ATTTTTAGAA ATACAGGTCA CAAAATAGAA ACAGACCTTC CCCAGATACG ATCGACCTTA 
ATTCCCATTT TACATCAAAA AGCAAAGAGG GGTACTCCAC ACCAAGCAAA ACAGGCTGTG 
CACTGTATAC ACGCCATATT CACAAATAAA GAAGTCCAGC TTGCACAGAT TTTTGAGCCA 
CTCAGTAGGA GTCTGAATGC TGATGTGCCA GAACAACTTA TAACTCCATT AGTTTCATTG 
GGCCACATTT CTATGTTAGC ACCAGATCAG TTTGCTTCCC CAATGAAATC TGTAGTAGCA 
AATTTTATTG TGAAAGATCT GCTAATGAAT GACAGGTCAA CAGGTGAAAA GAATGGAAAA 
CTGTGGTCTC CAGATGAAGA GGTTTCCCCT GAAGTACTAG CAAAGGTACA GGCAATTAAA 
CTTCTGGTAA GGTGGCTGTT GGGTATGAAA AACAACCAGT CTAAATCTGC CAATTCAACC 
CTTCGGTTAT TATCAGCGAT GTTGGTTAGT GAGGGTGACC TGACAGAGCA AAAGAGGATC 
AGTAAATCTG ATATGTCTCG CTTGCGATTA GCTGCTGGTA GTGCCATAAT GAAGCTTGCT 
CAGGAACCTT GTTACCATGA AATTATTACC CCAGAACAGT TTCAGCTCTG TGCACTTGTT 
ATTAATGATG AGTGTTACCA AGTAAGGCAG ATATTTGCTC AGAAGCTGCA TAAGGCACTT 
GTGAAGTTAC TGCTCCCATT GGAGTATATG GCGATCTTTG CCTTGTGTGC CAAAGATCCT 
GTGAAGGAGA GAAGAGCACA CGCACGACAA TGTTTACTGA AAAATATCAG TATACGCAGG 
GAATACATTA AGCAGAATCC TATGGCTACT GAGAAATTAT TATCACTGTT GCCTGAATAT 
GTAGTTCCAT ACATGATTCA CCTGCTAGCC CATGATCCAG ATTTTACAAG ATCACAAGAT 
GTTGATCAGC TTCGTGATAT CAAAGAGTGC CTATGGTTCA TGCTTGAAGT TTTAATGACA 
AAGAATGAAA ACAATAGCCA TGCCTTTATG AAGAAGATGG CAGAGAACAT CAAGTTAACC 
AGAGATGCCC AGTCTCCAGA TGAATCCAAG ACAAATGAAA AACTGTATAC AGTATGTGAT 
GTGGCTCTCT GTGTTATAAA TAGTAAAAGT GCTTTGTGCA ATGCAGATTC ACCAAAGGAC 
CCAGTCCTCC CAATGAAATT TTTTACACAA CCTGAAAAGG ACTTCTGTAA CGATAAGAGT 
TATATTTCAG AAGAGACAAG AGTACTTCTG TTAACAGGAA AGCCAAAGCC TGCTGGAGTA 
CTAGGTGCAG TAAATAAGCC TTTATCAGCA ACGGGAAGGA AACCCTATGT TAGAAGCACT 
GGCACTGAGA CTGGAAGCAA TATTAATGTA AATTCAGAGC TGAACCCTTC AACCGGAAAT 
CGATCAAGGG AACAGAGTTC AGAGGCAGCA GAAACTGGAG TTAGTGAAAA TGAAGAGAAC 
CCTGTGAGGA TTATTTCAGT CACACCTGTA AAGAATATTG ACCCAGTAAA GAATAAGGAA 
ATTAATTCTG ATCAGGCTAC CCAGGGCAAC ATCAGCAGTG ACCGAGGAAA GAAAAGAACA 
GTAACAGCAG CTGGTGCAGA GAATATCCAA CAAAAAACAG ATGAGAAAGT AGATGAATCG 
GGACCTCCCG CCCCTTCCAA ACCCAGGAGA GGACGTCGAC CCAAGTCTGA ATCTCAGGGC 
AATGCTACCA AAAATGATGA TCTAAATAAA CCTATTAACA AGGGAAGGAA GAGAGCTGCA 
GTGGGTCAGG AGAGCCCTGG GGGTTTGGAA GCAGGTAATG CCAAAGCACC CAAACTGCAA 
GATTTAGCCA AAAAGGCAGC ACCAGCAGAA AGACAAATTG ACTTACAAAG GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093869.1
CDS	541..4554
Translation	MDFTAQPKPATALCGVVSADGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADICVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDTAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFTNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVQAIKLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMATEKLLSLLPEYVVPYMIHLLAHDPDFTRSQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTRDAQSPDESKTNEKLYTVCDVALCVINSKSALCNADSPKDPVLPMKFFTQPEKDFCNDKSYISEETRVLLLTGKPKPAGVLGAVNKPLSATGRKPYVRSTGTETGSNINVNSELNPSTGNRSREQSSEAAETGVSENEENPVRIISVTPVKNIDPVKNKEINSDQATQGNISSDRGKKRTVTAAGAENIQQKTDEKVDESGPPAPSKPRRGRRPKSESQGNATKNDDLNKPINKGRKRAAVGQESPGGLEAGNAKAPKLQDLAKKAAPAERQIDLQR

Target ORF information:

RefSeq Version	NM_001100399.1
Organism	Homo sapiens(human)
Definition	Homo sapiens PDS5 cohesin associated factor A (PDS5A), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001100399.1

ORF Insert Sequence:

ATGGACTTCA CCGCGCAGCC CAAGCCTGCC ACTGCCCTCT GTGGCGTCGT GAGTGCCGAC 
GGGAAGATCG CTTACCCTCC GGGGGTAAAA GAGATCACCG ACAAGATCAC CACGGACGAG 
ATGATCAAAC GCCTGAAGAT GGTAGTGAAA ACCTTTATGG ATATGGATCA GGACTCAGAA 
GATGAAAAAC AGCAGTATCT CCCACTAGCC TTGCATCTTG CATCTGAATT CTTCCTCAGG 
AACCCCAATA AAGATGTGCG TCTCCTTGTA GCATGTTGTT TGGCTGATAT CTTTCGTATC 
TATGCCCCAG AAGCTCCATA TACTTCCCAT GATAAACTTA AGGACATATT TTTGTTTATT 
ACCAGACAAT TAAAAGGTTT GGAGGATACA AAGAGTCCAC AGTTTAATAG ATACTTTTAT 
TTATTAGAGA ATTTAGCTTG GGTTAAATCA TATAACATCT GCTTTGAATT GGAAGATTGC 
AATGAAATTT TTATTCAGCT TTTTAGAACT CTCTTCTCAG TGATCAACAA TAGCCACAAT 
AAGAAGGTAC AAATGCACAT GCTAGATTTG ATGAGTTCTA TCATCATGGA AGGTGATGGA 
GTTACTCAAG AATTATTGGA CTCCATTCTT ATTAACCTCA TTCCTGCACA TAAGAACTTA 
AATAAACAGT CCTTTGACCT TGCAAAAGTG CTATTGAAAA GAACAGTCCA GACTATTGAG 
GCATGCATTG CTAATTTTTT CAATCAAGTC CTGGTGCTGG GAAGATCATC AGTAAGTGAT 
TTGTCAGAAC ATGTATTTGA TCTGATTCAG GAACTTTTTG CTATAGATCC TCATTTATTA 
TTATCCGTCA TGCCACAGCT TGAATTCAAA CTAAAGAGCA ATGATGGAGA AGAGCGATTA 
GCTGTTGTTC GACTTCTAGC TAAATTGTTT GGCTCCAAAG ATTCTGATTT GGCAACACAG 
AATCGTCCTC TTTGGCAATG TTTTCTTGGA CGATTTAATG ATATTCATGT TCCTGTGAGA 
TTAGAAAGTG TGAAATTTGC CAGTCATTGT TTAATGAATC ACCCAGATTT AGCGAAGGAT 
CTCACAGAAT ATTTAAAGGT TAGATCACAT GATCCAGAAG AAGCTATTCG TCATGATGTC 
ATTGTTACTA TAATAACAGC TGCCAAGAGG GACCTGGCCT TAGTAAATGA TCAGCTGCTT 
GGCTTTGTAA GGGAAAGAAC ACTGGATAAA CGGTGGCGAG TAAGAAAAGA AGCTATGATG 
GGTCTGGCTC AGCTTTATAA GAAATACTGT CTTCATGGTG AAGCAGGAAA GGAAGCTGCA 
GAGAAAGTCA GCTGGATAAA GGACAAACTT CTGCATATTT ATTATCAGAA CAGCATTGAC 
GACAAACTGT TGGTAGAGAA AATCTTTGCT CAGTATCTTG TCCCCCACAA CCTGGAAACA 
GAAGAGAGAA TGAAATGCTT ATATTACTTA TATGCTAGTT TGGATCCAAA TGCTGTAAAA 
GCTCTCAACG AAATGTGGAA GTGTCAGAAC ATGCTTCGGA GCCATGTACG CGAACTATTG 
GATTTGCACA AGCAGCCTAC ATCAGAGGCT AACTGTTCTG CCATGTTTGG AAAACTGATG 
ACCATAGCAA AGAATTTGCC TGACCCCGGG AAAGCACAAG ATTTTGTGAA GAAATTTAAC 
CAGGTTCTCG GCGATGATGA GAAACTTCGG TCTCAGTTGG AGTTATTAAT TAGCCCAACC 
TGTTCTTGCA AACAAGCAGA TATTTGTGTG AGAGAAATAG CCCGGAAACT TGCAAATCCT 
AAGCAACCAA CAAATCCTTT TCTAGAGATG GTCAAATTTC TGTTGGAAAG AATCGCACCT 
GTGCACATTG ATTCAGAAGC CATAAGTGCA CTAGTGAAAT TGATGAATAA GTCAATAGAG 
GGGACAGCAG ATGATGAAGA GGAGGGTGTA AGTCCAGATA CAGCTATCCG TTCAGGACTT 
GAACTTCTTA AGGTTCTGTC TTTTACACAT CCTACCTCGT TCCACTCTGC AGAGACATAT 
GAGTCCTTGT TACAGTGCCT AAGAATGGAG GATGACAAGG TAGCAGAAGC TGCTATTCAA 
ATTTTTAGAA ATACAGGTCA CAAAATAGAA ACAGACCTTC CCCAGATACG ATCGACCTTA 
ATTCCCATTT TACATCAAAA AGCAAAGAGG GGTACTCCAC ACCAAGCAAA ACAGGCTGTG 
CACTGTATAC ACGCCATATT CACAAATAAA GAAGTCCAGC TTGCACAGAT TTTTGAGCCA 
CTCAGTAGGA GTCTGAATGC TGATGTGCCA GAACAACTTA TAACTCCATT AGTTTCATTG 
GGCCACATTT CTATGTTAGC ACCAGATCAG TTTGCTTCCC CAATGAAATC TGTAGTAGCA 
AATTTTATTG TGAAAGATCT GCTAATGAAT GACAGGTCAA CAGGTGAAAA GAATGGAAAA 
CTGTGGTCTC CAGATGAAGA GGTTTCCCCT GAAGTACTAG CAAAGGTACA GGCAATTAAA 
CTTCTGGTAA GGTGGCTGTT GGGTATGAAA AACAACCAGT CTAAATCTGC CAATTCAACC 
CTTCGGTTAT TATCAGCGAT GTTGGTTAGT GAGGGTGACC TGACAGAGCA AAAGAGGATC 
AGTAAATCTG ATATGTCTCG CTTGCGATTA GCTGCTGGTA GTGCCATAAT GAAGCTTGCT 
CAGGAACCTT GTTACCATGA AATTATTACC CCAGAACAGT TTCAGCTCTG TGCACTTGTT 
ATTAATGATG AGTGTTACCA AGTAAGGCAG ATATTTGCTC AGAAGCTGCA TAAGGCACTT 
GTGAAGTTAC TGCTCCCATT GGAGTATATG GCGATCTTTG CCTTGTGTGC CAAAGATCCT 
GTGAAGGAGA GAAGAGCACA CGCACGACAA TGTTTACTGA AAAATATCAG TATACGCAGG 
GAATACATTA AGCAGAATCC TATGGCTACT GAGAAATTAT TATCACTGTT GCCTGAATAT 
GTAGTTCCAT ACATGATTCA CCTGCTAGCC CATGATCCAG ATTTTACAAG ATCACAAGAT 
GTTGATCAGC TTCGTGATAT CAAAGAGTGC CTATGGTTCA TGCTTGAAGT TTTAATGACA 
AAGAATGAAA ACAATAGCCA TGCCTTTATG AAGAAGATGG CAGAGAACAT CAAGTTAACC 
AGAGATGCCC AGTCTCCAGA TGAATCCAAG ACAAATGAAA AACTGTATAC AGTATGTGAT 
GTGGCTCTCT GTGTTATAAA TAGTAAAAGT GCTTTGTGCA ATGCAGATTC ACCAAAGGAC 
CCAGTCCTCC CAATGAAATT TTTTACACAA CCTGAAAAGG ACTTCTGTAA CGATAAGAGT 
TATATTTCAG AAGAGACAAG AGTACTTCTG TTAACAGGAA AGCCAAAGCC TGCTGGAGTA 
CTAGGTGCAG TAAATAAGCC TTTATCAGCA ACGGGAAGGA AACCCTATGT TAGAAGCACT 
GGCACTGAGA CTGGAAGCAA TATTAATGTA AATTCAGAGC TGAACCCTTC AACCGGAAAT 
CGATCAAGGG AACAGAGTTC AGAGGCAGCA GAAACTGGAG TTAGTGAAAA TGAAGAGAAC 
CCTGTGAGGA TTATTTCAGT CACACCTGTA AAGAATATTG ACCCAGTAAA GAATAAGGAA 
ATTAATTCTG ATCAGGCTAC CCAGGGCAAC ATCAGCAGTG ACCGAGGAAA GAAAAGAACA 
GTAACAGCAG CTGGTGCAGA GAATATCCAA CAAAAAACAG ATGAGAAAGT AGATGAATCG 
GGACCTCCCG CCCCTTCCAA ACCCAGGAGA GGACGTCGAC CCAAGTCTGA ATCTCAGGGC 
AATGCTACCA AAAATGATGA TCTAAATAAA CCTATTAACA AGGGAAGGAA GAGAGCTGCA 
GTGGGTCAGG AGAGCCCTGG GGGTTTGGAA GCAGGTAATG CCAAAGCACC CAAACTGCAA 
GATTTAGCCA AAAAGGCAGC ACCAGCAGAA AGACAAATTG ACTTACAAAG GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PDS5A ( XM_011513672.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011511974.1 Homo sapiens PDS5 cohesin associated factor A (PDS5A), transcript variant X5, mRNA.

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CloneID	OHu19510
Clone ID Related Accession (Same CDS sequence)	NM_001100399.2 , XM_011513672.2 , NM_001100399.1 , XM_017007928.1
Accession Version	XM_011513672.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	sister chromatid cohesion protein PDS5 homolog A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011513672.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACTTCA CCGCGCAGCC CAAGCCTGCC ACTGCCCTCT GTGGCGTCGT GAGTGCCGAC 
GGGAAGATCG CTTACCCTCC GGGGGTAAAA GAGATCACCG ACAAGATCAC CACGGACGAG 
ATGATCAAAC GCCTGAAGAT GGTAGTGAAA ACCTTTATGG ATATGGATCA GGACTCAGAA 
GATGAAAAAC AGCAGTATCT CCCACTAGCC TTGCATCTTG CATCTGAATT CTTCCTCAGG 
AACCCCAATA AAGATGTGCG TCTCCTTGTA GCATGTTGTT TGGCTGATAT CTTTCGTATC 
TATGCCCCAG AAGCTCCATA TACTTCCCAT GATAAACTTA AGGACATATT TTTGTTTATT 
ACCAGACAAT TAAAAGGTTT GGAGGATACA AAGAGTCCAC AGTTTAATAG ATACTTTTAT 
TTATTAGAGA ATTTAGCTTG GGTTAAATCA TATAACATCT GCTTTGAATT GGAAGATTGC 
AATGAAATTT TTATTCAGCT TTTTAGAACT CTCTTCTCAG TGATCAACAA TAGCCACAAT 
AAGAAGGTAC AAATGCACAT GCTAGATTTG ATGAGTTCTA TCATCATGGA AGGTGATGGA 
GTTACTCAAG AATTATTGGA CTCCATTCTT ATTAACCTCA TTCCTGCACA TAAGAACTTA 
AATAAACAGT CCTTTGACCT TGCAAAAGTG CTATTGAAAA GAACAGTCCA GACTATTGAG 
GCATGCATTG CTAATTTTTT CAATCAAGTC CTGGTGCTGG GAAGATCATC AGTAAGTGAT 
TTGTCAGAAC ATGTATTTGA TCTGATTCAG GAACTTTTTG CTATAGATCC TCATTTATTA 
TTATCCGTCA TGCCACAGCT TGAATTCAAA CTAAAGAGCA ATGATGGAGA AGAGCGATTA 
GCTGTTGTTC GACTTCTAGC TAAATTGTTT GGCTCCAAAG ATTCTGATTT GGCAACACAG 
AATCGTCCTC TTTGGCAATG TTTTCTTGGA CGATTTAATG ATATTCATGT TCCTGTGAGA 
TTAGAAAGTG TGAAATTTGC CAGTCATTGT TTAATGAATC ACCCAGATTT AGCGAAGGAT 
CTCACAGAAT ATTTAAAGGT TAGATCACAT GATCCAGAAG AAGCTATTCG TCATGATGTC 
ATTGTTACTA TAATAACAGC TGCCAAGAGG GACCTGGCCT TAGTAAATGA TCAGCTGCTT 
GGCTTTGTAA GGGAAAGAAC ACTGGATAAA CGGTGGCGAG TAAGAAAAGA AGCTATGATG 
GGTCTGGCTC AGCTTTATAA GAAATACTGT CTTCATGGTG AAGCAGGAAA GGAAGCTGCA 
GAGAAAGTCA GCTGGATAAA GGACAAACTT CTGCATATTT ATTATCAGAA CAGCATTGAC 
GACAAACTGT TGGTAGAGAA AATCTTTGCT CAGTATCTTG TCCCCCACAA CCTGGAAACA 
GAAGAGAGAA TGAAATGCTT ATATTACTTA TATGCTAGTT TGGATCCAAA TGCTGTAAAA 
GCTCTCAACG AAATGTGGAA GTGTCAGAAC ATGCTTCGGA GCCATGTACG CGAACTATTG 
GATTTGCACA AGCAGCCTAC ATCAGAGGCT AACTGTTCTG CCATGTTTGG AAAACTGATG 
ACCATAGCAA AGAATTTGCC TGACCCCGGG AAAGCACAAG ATTTTGTGAA GAAATTTAAC 
CAGGTTCTCG GCGATGATGA GAAACTTCGG TCTCAGTTGG AGTTATTAAT TAGCCCAACC 
TGTTCTTGCA AACAAGCAGA TATTTGTGTG AGAGAAATAG CCCGGAAACT TGCAAATCCT 
AAGCAACCAA CAAATCCTTT TCTAGAGATG GTCAAATTTC TGTTGGAAAG AATCGCACCT 
GTGCACATTG ATTCAGAAGC CATAAGTGCA CTAGTGAAAT TGATGAATAA GTCAATAGAG 
GGGACAGCAG ATGATGAAGA GGAGGGTGTA AGTCCAGATA CAGCTATCCG TTCAGGACTT 
GAACTTCTTA AGGTTCTGTC TTTTACACAT CCTACCTCGT TCCACTCTGC AGAGACATAT 
GAGTCCTTGT TACAGTGCCT AAGAATGGAG GATGACAAGG TAGCAGAAGC TGCTATTCAA 
ATTTTTAGAA ATACAGGTCA CAAAATAGAA ACAGACCTTC CCCAGATACG ATCGACCTTA 
ATTCCCATTT TACATCAAAA AGCAAAGAGG GGTACTCCAC ACCAAGCAAA ACAGGCTGTG 
CACTGTATAC ACGCCATATT CACAAATAAA GAAGTCCAGC TTGCACAGAT TTTTGAGCCA 
CTCAGTAGGA GTCTGAATGC TGATGTGCCA GAACAACTTA TAACTCCATT AGTTTCATTG 
GGCCACATTT CTATGTTAGC ACCAGATCAG TTTGCTTCCC CAATGAAATC TGTAGTAGCA 
AATTTTATTG TGAAAGATCT GCTAATGAAT GACAGGTCAA CAGGTGAAAA GAATGGAAAA 
CTGTGGTCTC CAGATGAAGA GGTTTCCCCT GAAGTACTAG CAAAGGTACA GGCAATTAAA 
CTTCTGGTAA GGTGGCTGTT GGGTATGAAA AACAACCAGT CTAAATCTGC CAATTCAACC 
CTTCGGTTAT TATCAGCGAT GTTGGTTAGT GAGGGTGACC TGACAGAGCA AAAGAGGATC 
AGTAAATCTG ATATGTCTCG CTTGCGATTA GCTGCTGGTA GTGCCATAAT GAAGCTTGCT 
CAGGAACCTT GTTACCATGA AATTATTACC CCAGAACAGT TTCAGCTCTG TGCACTTGTT 
ATTAATGATG AGTGTTACCA AGTAAGGCAG ATATTTGCTC AGAAGCTGCA TAAGGCACTT 
GTGAAGTTAC TGCTCCCATT GGAGTATATG GCGATCTTTG CCTTGTGTGC CAAAGATCCT 
GTGAAGGAGA GAAGAGCACA CGCACGACAA TGTTTACTGA AAAATATCAG TATACGCAGG 
GAATACATTA AGCAGAATCC TATGGCTACT GAGAAATTAT TATCACTGTT GCCTGAATAT 
GTAGTTCCAT ACATGATTCA CCTGCTAGCC CATGATCCAG ATTTTACAAG ATCACAAGAT 
GTTGATCAGC TTCGTGATAT CAAAGAGTGC CTATGGTTCA TGCTTGAAGT TTTAATGACA 
AAGAATGAAA ACAATAGCCA TGCCTTTATG AAGAAGATGG CAGAGAACAT CAAGTTAACC 
AGAGATGCCC AGTCTCCAGA TGAATCCAAG ACAAATGAAA AACTGTATAC AGTATGTGAT 
GTGGCTCTCT GTGTTATAAA TAGTAAAAGT GCTTTGTGCA ATGCAGATTC ACCAAAGGAC 
CCAGTCCTCC CAATGAAATT TTTTACACAA CCTGAAAAGG ACTTCTGTAA CGATAAGAGT 
TATATTTCAG AAGAGACAAG AGTACTTCTG TTAACAGGAA AGCCAAAGCC TGCTGGAGTA 
CTAGGTGCAG TAAATAAGCC TTTATCAGCA ACGGGAAGGA AACCCTATGT TAGAAGCACT 
GGCACTGAGA CTGGAAGCAA TATTAATGTA AATTCAGAGC TGAACCCTTC AACCGGAAAT 
CGATCAAGGG AACAGAGTTC AGAGGCAGCA GAAACTGGAG TTAGTGAAAA TGAAGAGAAC 
CCTGTGAGGA TTATTTCAGT CACACCTGTA AAGAATATTG ACCCAGTAAA GAATAAGGAA 
ATTAATTCTG ATCAGGCTAC CCAGGGCAAC ATCAGCAGTG ACCGAGGAAA GAAAAGAACA 
GTAACAGCAG CTGGTGCAGA GAATATCCAA CAAAAAACAG ATGAGAAAGT AGATGAATCG 
GGACCTCCCG CCCCTTCCAA ACCCAGGAGA GGACGTCGAC CCAAGTCTGA ATCTCAGGGC 
AATGCTACCA AAAATGATGA TCTAAATAAA CCTATTAACA AGGGAAGGAA GAGAGCTGCA 
GTGGGTCAGG AGAGCCCTGG GGGTTTGGAA GCAGGTAATG CCAAAGCACC CAAACTGCAA 
GATTTAGCCA AAAAGGCAGC ACCAGCAGAA AGACAAATTG ACTTACAAAG GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011511974.1
CDS	154..4167
Translation	MDFTAQPKPATALCGVVSADGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADICVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDTAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFTNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVQAIKLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMATEKLLSLLPEYVVPYMIHLLAHDPDFTRSQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTRDAQSPDESKTNEKLYTVCDVALCVINSKSALCNADSPKDPVLPMKFFTQPEKDFCNDKSYISEETRVLLLTGKPKPAGVLGAVNKPLSATGRKPYVRSTGTETGSNINVNSELNPSTGNRSREQSSEAAETGVSENEENPVRIISVTPVKNIDPVKNKEINSDQATQGNISSDRGKKRTVTAAGAENIQQKTDEKVDESGPPAPSKPRRGRRPKSESQGNATKNDDLNKPINKGRKRAAVGQESPGGLEAGNAKAPKLQDLAKKAAPAERQIDLQR

Target ORF information:

RefSeq Version	XM_011513672.2
Organism	Homo sapiens(human)
Definition	Homo sapiens PDS5 cohesin associated factor A (PDS5A), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011513672.2

ORF Insert Sequence:

ATGGACTTCA CCGCGCAGCC CAAGCCTGCC ACTGCCCTCT GTGGCGTCGT GAGTGCCGAC 
GGGAAGATCG CTTACCCTCC GGGGGTAAAA GAGATCACCG ACAAGATCAC CACGGACGAG 
ATGATCAAAC GCCTGAAGAT GGTAGTGAAA ACCTTTATGG ATATGGATCA GGACTCAGAA 
GATGAAAAAC AGCAGTATCT CCCACTAGCC TTGCATCTTG CATCTGAATT CTTCCTCAGG 
AACCCCAATA AAGATGTGCG TCTCCTTGTA GCATGTTGTT TGGCTGATAT CTTTCGTATC 
TATGCCCCAG AAGCTCCATA TACTTCCCAT GATAAACTTA AGGACATATT TTTGTTTATT 
ACCAGACAAT TAAAAGGTTT GGAGGATACA AAGAGTCCAC AGTTTAATAG ATACTTTTAT 
TTATTAGAGA ATTTAGCTTG GGTTAAATCA TATAACATCT GCTTTGAATT GGAAGATTGC 
AATGAAATTT TTATTCAGCT TTTTAGAACT CTCTTCTCAG TGATCAACAA TAGCCACAAT 
AAGAAGGTAC AAATGCACAT GCTAGATTTG ATGAGTTCTA TCATCATGGA AGGTGATGGA 
GTTACTCAAG AATTATTGGA CTCCATTCTT ATTAACCTCA TTCCTGCACA TAAGAACTTA 
AATAAACAGT CCTTTGACCT TGCAAAAGTG CTATTGAAAA GAACAGTCCA GACTATTGAG 
GCATGCATTG CTAATTTTTT CAATCAAGTC CTGGTGCTGG GAAGATCATC AGTAAGTGAT 
TTGTCAGAAC ATGTATTTGA TCTGATTCAG GAACTTTTTG CTATAGATCC TCATTTATTA 
TTATCCGTCA TGCCACAGCT TGAATTCAAA CTAAAGAGCA ATGATGGAGA AGAGCGATTA 
GCTGTTGTTC GACTTCTAGC TAAATTGTTT GGCTCCAAAG ATTCTGATTT GGCAACACAG 
AATCGTCCTC TTTGGCAATG TTTTCTTGGA CGATTTAATG ATATTCATGT TCCTGTGAGA 
TTAGAAAGTG TGAAATTTGC CAGTCATTGT TTAATGAATC ACCCAGATTT AGCGAAGGAT 
CTCACAGAAT ATTTAAAGGT TAGATCACAT GATCCAGAAG AAGCTATTCG TCATGATGTC 
ATTGTTACTA TAATAACAGC TGCCAAGAGG GACCTGGCCT TAGTAAATGA TCAGCTGCTT 
GGCTTTGTAA GGGAAAGAAC ACTGGATAAA CGGTGGCGAG TAAGAAAAGA AGCTATGATG 
GGTCTGGCTC AGCTTTATAA GAAATACTGT CTTCATGGTG AAGCAGGAAA GGAAGCTGCA 
GAGAAAGTCA GCTGGATAAA GGACAAACTT CTGCATATTT ATTATCAGAA CAGCATTGAC 
GACAAACTGT TGGTAGAGAA AATCTTTGCT CAGTATCTTG TCCCCCACAA CCTGGAAACA 
GAAGAGAGAA TGAAATGCTT ATATTACTTA TATGCTAGTT TGGATCCAAA TGCTGTAAAA 
GCTCTCAACG AAATGTGGAA GTGTCAGAAC ATGCTTCGGA GCCATGTACG CGAACTATTG 
GATTTGCACA AGCAGCCTAC ATCAGAGGCT AACTGTTCTG CCATGTTTGG AAAACTGATG 
ACCATAGCAA AGAATTTGCC TGACCCCGGG AAAGCACAAG ATTTTGTGAA GAAATTTAAC 
CAGGTTCTCG GCGATGATGA GAAACTTCGG TCTCAGTTGG AGTTATTAAT TAGCCCAACC 
TGTTCTTGCA AACAAGCAGA TATTTGTGTG AGAGAAATAG CCCGGAAACT TGCAAATCCT 
AAGCAACCAA CAAATCCTTT TCTAGAGATG GTCAAATTTC TGTTGGAAAG AATCGCACCT 
GTGCACATTG ATTCAGAAGC CATAAGTGCA CTAGTGAAAT TGATGAATAA GTCAATAGAG 
GGGACAGCAG ATGATGAAGA GGAGGGTGTA AGTCCAGATA CAGCTATCCG TTCAGGACTT 
GAACTTCTTA AGGTTCTGTC TTTTACACAT CCTACCTCGT TCCACTCTGC AGAGACATAT 
GAGTCCTTGT TACAGTGCCT AAGAATGGAG GATGACAAGG TAGCAGAAGC TGCTATTCAA 
ATTTTTAGAA ATACAGGTCA CAAAATAGAA ACAGACCTTC CCCAGATACG ATCGACCTTA 
ATTCCCATTT TACATCAAAA AGCAAAGAGG GGTACTCCAC ACCAAGCAAA ACAGGCTGTG 
CACTGTATAC ACGCCATATT CACAAATAAA GAAGTCCAGC TTGCACAGAT TTTTGAGCCA 
CTCAGTAGGA GTCTGAATGC TGATGTGCCA GAACAACTTA TAACTCCATT AGTTTCATTG 
GGCCACATTT CTATGTTAGC ACCAGATCAG TTTGCTTCCC CAATGAAATC TGTAGTAGCA 
AATTTTATTG TGAAAGATCT GCTAATGAAT GACAGGTCAA CAGGTGAAAA GAATGGAAAA 
CTGTGGTCTC CAGATGAAGA GGTTTCCCCT GAAGTACTAG CAAAGGTACA GGCAATTAAA 
CTTCTGGTAA GGTGGCTGTT GGGTATGAAA AACAACCAGT CTAAATCTGC CAATTCAACC 
CTTCGGTTAT TATCAGCGAT GTTGGTTAGT GAGGGTGACC TGACAGAGCA AAAGAGGATC 
AGTAAATCTG ATATGTCTCG CTTGCGATTA GCTGCTGGTA GTGCCATAAT GAAGCTTGCT 
CAGGAACCTT GTTACCATGA AATTATTACC CCAGAACAGT TTCAGCTCTG TGCACTTGTT 
ATTAATGATG AGTGTTACCA AGTAAGGCAG ATATTTGCTC AGAAGCTGCA TAAGGCACTT 
GTGAAGTTAC TGCTCCCATT GGAGTATATG GCGATCTTTG CCTTGTGTGC CAAAGATCCT 
GTGAAGGAGA GAAGAGCACA CGCACGACAA TGTTTACTGA AAAATATCAG TATACGCAGG 
GAATACATTA AGCAGAATCC TATGGCTACT GAGAAATTAT TATCACTGTT GCCTGAATAT 
GTAGTTCCAT ACATGATTCA CCTGCTAGCC CATGATCCAG ATTTTACAAG ATCACAAGAT 
GTTGATCAGC TTCGTGATAT CAAAGAGTGC CTATGGTTCA TGCTTGAAGT TTTAATGACA 
AAGAATGAAA ACAATAGCCA TGCCTTTATG AAGAAGATGG CAGAGAACAT CAAGTTAACC 
AGAGATGCCC AGTCTCCAGA TGAATCCAAG ACAAATGAAA AACTGTATAC AGTATGTGAT 
GTGGCTCTCT GTGTTATAAA TAGTAAAAGT GCTTTGTGCA ATGCAGATTC ACCAAAGGAC 
CCAGTCCTCC CAATGAAATT TTTTACACAA CCTGAAAAGG ACTTCTGTAA CGATAAGAGT 
TATATTTCAG AAGAGACAAG AGTACTTCTG TTAACAGGAA AGCCAAAGCC TGCTGGAGTA 
CTAGGTGCAG TAAATAAGCC TTTATCAGCA ACGGGAAGGA AACCCTATGT TAGAAGCACT 
GGCACTGAGA CTGGAAGCAA TATTAATGTA AATTCAGAGC TGAACCCTTC AACCGGAAAT 
CGATCAAGGG AACAGAGTTC AGAGGCAGCA GAAACTGGAG TTAGTGAAAA TGAAGAGAAC 
CCTGTGAGGA TTATTTCAGT CACACCTGTA AAGAATATTG ACCCAGTAAA GAATAAGGAA 
ATTAATTCTG ATCAGGCTAC CCAGGGCAAC ATCAGCAGTG ACCGAGGAAA GAAAAGAACA 
GTAACAGCAG CTGGTGCAGA GAATATCCAA CAAAAAACAG ATGAGAAAGT AGATGAATCG 
GGACCTCCCG CCCCTTCCAA ACCCAGGAGA GGACGTCGAC CCAAGTCTGA ATCTCAGGGC 
AATGCTACCA AAAATGATGA TCTAAATAAA CCTATTAACA AGGGAAGGAA GAGAGCTGCA 
GTGGGTCAGG AGAGCCCTGG GGGTTTGGAA GCAGGTAATG CCAAAGCACC CAAACTGCAA 
GATTTAGCCA AAAAGGCAGC ACCAGCAGAA AGACAAATTG ACTTACAAAG GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PDS5A ( XM_017007928.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016863417.1 Homo sapiens PDS5 cohesin associated factor A (PDS5A), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OHu19510
Clone ID Related Accession (Same CDS sequence)	NM_001100399.2 , XM_011513672.2 , NM_001100399.1 , XM_017007928.1
Accession Version	XM_017007928.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	sister chromatid cohesion protein PDS5 homolog A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACTTCA CCGCGCAGCC CAAGCCTGCC ACTGCCCTCT GTGGCGTCGT GAGTGCCGAC 
GGGAAGATCG CTTACCCTCC GGGGGTAAAA GAGATCACCG ACAAGATCAC CACGGACGAG 
ATGATCAAAC GCCTGAAGAT GGTAGTGAAA ACCTTTATGG ATATGGATCA GGACTCAGAA 
GATGAAAAAC AGCAGTATCT CCCACTAGCC TTGCATCTTG CATCTGAATT CTTCCTCAGG 
AACCCCAATA AAGATGTGCG TCTCCTTGTA GCATGTTGTT TGGCTGATAT CTTTCGTATC 
TATGCCCCAG AAGCTCCATA TACTTCCCAT GATAAACTTA AGGACATATT TTTGTTTATT 
ACCAGACAAT TAAAAGGTTT GGAGGATACA AAGAGTCCAC AGTTTAATAG ATACTTTTAT 
TTATTAGAGA ATTTAGCTTG GGTTAAATCA TATAACATCT GCTTTGAATT GGAAGATTGC 
AATGAAATTT TTATTCAGCT TTTTAGAACT CTCTTCTCAG TGATCAACAA TAGCCACAAT 
AAGAAGGTAC AAATGCACAT GCTAGATTTG ATGAGTTCTA TCATCATGGA AGGTGATGGA 
GTTACTCAAG AATTATTGGA CTCCATTCTT ATTAACCTCA TTCCTGCACA TAAGAACTTA 
AATAAACAGT CCTTTGACCT TGCAAAAGTG CTATTGAAAA GAACAGTCCA GACTATTGAG 
GCATGCATTG CTAATTTTTT CAATCAAGTC CTGGTGCTGG GAAGATCATC AGTAAGTGAT 
TTGTCAGAAC ATGTATTTGA TCTGATTCAG GAACTTTTTG CTATAGATCC TCATTTATTA 
TTATCCGTCA TGCCACAGCT TGAATTCAAA CTAAAGAGCA ATGATGGAGA AGAGCGATTA 
GCTGTTGTTC GACTTCTAGC TAAATTGTTT GGCTCCAAAG ATTCTGATTT GGCAACACAG 
AATCGTCCTC TTTGGCAATG TTTTCTTGGA CGATTTAATG ATATTCATGT TCCTGTGAGA 
TTAGAAAGTG TGAAATTTGC CAGTCATTGT TTAATGAATC ACCCAGATTT AGCGAAGGAT 
CTCACAGAAT ATTTAAAGGT TAGATCACAT GATCCAGAAG AAGCTATTCG TCATGATGTC 
ATTGTTACTA TAATAACAGC TGCCAAGAGG GACCTGGCCT TAGTAAATGA TCAGCTGCTT 
GGCTTTGTAA GGGAAAGAAC ACTGGATAAA CGGTGGCGAG TAAGAAAAGA AGCTATGATG 
GGTCTGGCTC AGCTTTATAA GAAATACTGT CTTCATGGTG AAGCAGGAAA GGAAGCTGCA 
GAGAAAGTCA GCTGGATAAA GGACAAACTT CTGCATATTT ATTATCAGAA CAGCATTGAC 
GACAAACTGT TGGTAGAGAA AATCTTTGCT CAGTATCTTG TCCCCCACAA CCTGGAAACA 
GAAGAGAGAA TGAAATGCTT ATATTACTTA TATGCTAGTT TGGATCCAAA TGCTGTAAAA 
GCTCTCAACG AAATGTGGAA GTGTCAGAAC ATGCTTCGGA GCCATGTACG CGAACTATTG 
GATTTGCACA AGCAGCCTAC ATCAGAGGCT AACTGTTCTG CCATGTTTGG AAAACTGATG 
ACCATAGCAA AGAATTTGCC TGACCCCGGG AAAGCACAAG ATTTTGTGAA GAAATTTAAC 
CAGGTTCTCG GCGATGATGA GAAACTTCGG TCTCAGTTGG AGTTATTAAT TAGCCCAACC 
TGTTCTTGCA AACAAGCAGA TATTTGTGTG AGAGAAATAG CCCGGAAACT TGCAAATCCT 
AAGCAACCAA CAAATCCTTT TCTAGAGATG GTCAAATTTC TGTTGGAAAG AATCGCACCT 
GTGCACATTG ATTCAGAAGC CATAAGTGCA CTAGTGAAAT TGATGAATAA GTCAATAGAG 
GGGACAGCAG ATGATGAAGA GGAGGGTGTA AGTCCAGATA CAGCTATCCG TTCAGGACTT 
GAACTTCTTA AGGTTCTGTC TTTTACACAT CCTACCTCGT TCCACTCTGC AGAGACATAT 
GAGTCCTTGT TACAGTGCCT AAGAATGGAG GATGACAAGG TAGCAGAAGC TGCTATTCAA 
ATTTTTAGAA ATACAGGTCA CAAAATAGAA ACAGACCTTC CCCAGATACG ATCGACCTTA 
ATTCCCATTT TACATCAAAA AGCAAAGAGG GGTACTCCAC ACCAAGCAAA ACAGGCTGTG 
CACTGTATAC ACGCCATATT CACAAATAAA GAAGTCCAGC TTGCACAGAT TTTTGAGCCA 
CTCAGTAGGA GTCTGAATGC TGATGTGCCA GAACAACTTA TAACTCCATT AGTTTCATTG 
GGCCACATTT CTATGTTAGC ACCAGATCAG TTTGCTTCCC CAATGAAATC TGTAGTAGCA 
AATTTTATTG TGAAAGATCT GCTAATGAAT GACAGGTCAA CAGGTGAAAA GAATGGAAAA 
CTGTGGTCTC CAGATGAAGA GGTTTCCCCT GAAGTACTAG CAAAGGTACA GGCAATTAAA 
CTTCTGGTAA GGTGGCTGTT GGGTATGAAA AACAACCAGT CTAAATCTGC CAATTCAACC 
CTTCGGTTAT TATCAGCGAT GTTGGTTAGT GAGGGTGACC TGACAGAGCA AAAGAGGATC 
AGTAAATCTG ATATGTCTCG CTTGCGATTA GCTGCTGGTA GTGCCATAAT GAAGCTTGCT 
CAGGAACCTT GTTACCATGA AATTATTACC CCAGAACAGT TTCAGCTCTG TGCACTTGTT 
ATTAATGATG AGTGTTACCA AGTAAGGCAG ATATTTGCTC AGAAGCTGCA TAAGGCACTT 
GTGAAGTTAC TGCTCCCATT GGAGTATATG GCGATCTTTG CCTTGTGTGC CAAAGATCCT 
GTGAAGGAGA GAAGAGCACA CGCACGACAA TGTTTACTGA AAAATATCAG TATACGCAGG 
GAATACATTA AGCAGAATCC TATGGCTACT GAGAAATTAT TATCACTGTT GCCTGAATAT 
GTAGTTCCAT ACATGATTCA CCTGCTAGCC CATGATCCAG ATTTTACAAG ATCACAAGAT 
GTTGATCAGC TTCGTGATAT CAAAGAGTGC CTATGGTTCA TGCTTGAAGT TTTAATGACA 
AAGAATGAAA ACAATAGCCA TGCCTTTATG AAGAAGATGG CAGAGAACAT CAAGTTAACC 
AGAGATGCCC AGTCTCCAGA TGAATCCAAG ACAAATGAAA AACTGTATAC AGTATGTGAT 
GTGGCTCTCT GTGTTATAAA TAGTAAAAGT GCTTTGTGCA ATGCAGATTC ACCAAAGGAC 
CCAGTCCTCC CAATGAAATT TTTTACACAA CCTGAAAAGG ACTTCTGTAA CGATAAGAGT 
TATATTTCAG AAGAGACAAG AGTACTTCTG TTAACAGGAA AGCCAAAGCC TGCTGGAGTA 
CTAGGTGCAG TAAATAAGCC TTTATCAGCA ACGGGAAGGA AACCCTATGT TAGAAGCACT 
GGCACTGAGA CTGGAAGCAA TATTAATGTA AATTCAGAGC TGAACCCTTC AACCGGAAAT 
CGATCAAGGG AACAGAGTTC AGAGGCAGCA GAAACTGGAG TTAGTGAAAA TGAAGAGAAC 
CCTGTGAGGA TTATTTCAGT CACACCTGTA AAGAATATTG ACCCAGTAAA GAATAAGGAA 
ATTAATTCTG ATCAGGCTAC CCAGGGCAAC ATCAGCAGTG ACCGAGGAAA GAAAAGAACA 
GTAACAGCAG CTGGTGCAGA GAATATCCAA CAAAAAACAG ATGAGAAAGT AGATGAATCG 
GGACCTCCCG CCCCTTCCAA ACCCAGGAGA GGACGTCGAC CCAAGTCTGA ATCTCAGGGC 
AATGCTACCA AAAATGATGA TCTAAATAAA CCTATTAACA AGGGAAGGAA GAGAGCTGCA 
GTGGGTCAGG AGAGCCCTGG GGGTTTGGAA GCAGGTAATG CCAAAGCACC CAAACTGCAA 
GATTTAGCCA AAAAGGCAGC ACCAGCAGAA AGACAAATTG ACTTACAAAG GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016863417.1
CDS	116..4129
Translation	MDFTAQPKPATALCGVVSADGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVSDLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPTCSCKQADICVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDTAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFTNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVQAIKLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMATEKLLSLLPEYVVPYMIHLLAHDPDFTRSQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLTRDAQSPDESKTNEKLYTVCDVALCVINSKSALCNADSPKDPVLPMKFFTQPEKDFCNDKSYISEETRVLLLTGKPKPAGVLGAVNKPLSATGRKPYVRSTGTETGSNINVNSELNPSTGNRSREQSSEAAETGVSENEENPVRIISVTPVKNIDPVKNKEINSDQATQGNISSDRGKKRTVTAAGAENIQQKTDEKVDESGPPAPSKPRRGRRPKSESQGNATKNDDLNKPINKGRKRAAVGQESPGGLEAGNAKAPKLQDLAKKAAPAERQIDLQR

Target ORF information:

RefSeq Version	XM_017007928.1
Organism	Homo sapiens(human)
Definition	Homo sapiens PDS5 cohesin associated factor A (PDS5A), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017007928.1

ORF Insert Sequence:

ATGGACTTCA CCGCGCAGCC CAAGCCTGCC ACTGCCCTCT GTGGCGTCGT GAGTGCCGAC 
GGGAAGATCG CTTACCCTCC GGGGGTAAAA GAGATCACCG ACAAGATCAC CACGGACGAG 
ATGATCAAAC GCCTGAAGAT GGTAGTGAAA ACCTTTATGG ATATGGATCA GGACTCAGAA 
GATGAAAAAC AGCAGTATCT CCCACTAGCC TTGCATCTTG CATCTGAATT CTTCCTCAGG 
AACCCCAATA AAGATGTGCG TCTCCTTGTA GCATGTTGTT TGGCTGATAT CTTTCGTATC 
TATGCCCCAG AAGCTCCATA TACTTCCCAT GATAAACTTA AGGACATATT TTTGTTTATT 
ACCAGACAAT TAAAAGGTTT GGAGGATACA AAGAGTCCAC AGTTTAATAG ATACTTTTAT 
TTATTAGAGA ATTTAGCTTG GGTTAAATCA TATAACATCT GCTTTGAATT GGAAGATTGC 
AATGAAATTT TTATTCAGCT TTTTAGAACT CTCTTCTCAG TGATCAACAA TAGCCACAAT 
AAGAAGGTAC AAATGCACAT GCTAGATTTG ATGAGTTCTA TCATCATGGA AGGTGATGGA 
GTTACTCAAG AATTATTGGA CTCCATTCTT ATTAACCTCA TTCCTGCACA TAAGAACTTA 
AATAAACAGT CCTTTGACCT TGCAAAAGTG CTATTGAAAA GAACAGTCCA GACTATTGAG 
GCATGCATTG CTAATTTTTT CAATCAAGTC CTGGTGCTGG GAAGATCATC AGTAAGTGAT 
TTGTCAGAAC ATGTATTTGA TCTGATTCAG GAACTTTTTG CTATAGATCC TCATTTATTA 
TTATCCGTCA TGCCACAGCT TGAATTCAAA CTAAAGAGCA ATGATGGAGA AGAGCGATTA 
GCTGTTGTTC GACTTCTAGC TAAATTGTTT GGCTCCAAAG ATTCTGATTT GGCAACACAG 
AATCGTCCTC TTTGGCAATG TTTTCTTGGA CGATTTAATG ATATTCATGT TCCTGTGAGA 
TTAGAAAGTG TGAAATTTGC CAGTCATTGT TTAATGAATC ACCCAGATTT AGCGAAGGAT 
CTCACAGAAT ATTTAAAGGT TAGATCACAT GATCCAGAAG AAGCTATTCG TCATGATGTC 
ATTGTTACTA TAATAACAGC TGCCAAGAGG GACCTGGCCT TAGTAAATGA TCAGCTGCTT 
GGCTTTGTAA GGGAAAGAAC ACTGGATAAA CGGTGGCGAG TAAGAAAAGA AGCTATGATG 
GGTCTGGCTC AGCTTTATAA GAAATACTGT CTTCATGGTG AAGCAGGAAA GGAAGCTGCA 
GAGAAAGTCA GCTGGATAAA GGACAAACTT CTGCATATTT ATTATCAGAA CAGCATTGAC 
GACAAACTGT TGGTAGAGAA AATCTTTGCT CAGTATCTTG TCCCCCACAA CCTGGAAACA 
GAAGAGAGAA TGAAATGCTT ATATTACTTA TATGCTAGTT TGGATCCAAA TGCTGTAAAA 
GCTCTCAACG AAATGTGGAA GTGTCAGAAC ATGCTTCGGA GCCATGTACG CGAACTATTG 
GATTTGCACA AGCAGCCTAC ATCAGAGGCT AACTGTTCTG CCATGTTTGG AAAACTGATG 
ACCATAGCAA AGAATTTGCC TGACCCCGGG AAAGCACAAG ATTTTGTGAA GAAATTTAAC 
CAGGTTCTCG GCGATGATGA GAAACTTCGG TCTCAGTTGG AGTTATTAAT TAGCCCAACC 
TGTTCTTGCA AACAAGCAGA TATTTGTGTG AGAGAAATAG CCCGGAAACT TGCAAATCCT 
AAGCAACCAA CAAATCCTTT TCTAGAGATG GTCAAATTTC TGTTGGAAAG AATCGCACCT 
GTGCACATTG ATTCAGAAGC CATAAGTGCA CTAGTGAAAT TGATGAATAA GTCAATAGAG 
GGGACAGCAG ATGATGAAGA GGAGGGTGTA AGTCCAGATA CAGCTATCCG TTCAGGACTT 
GAACTTCTTA AGGTTCTGTC TTTTACACAT CCTACCTCGT TCCACTCTGC AGAGACATAT 
GAGTCCTTGT TACAGTGCCT AAGAATGGAG GATGACAAGG TAGCAGAAGC TGCTATTCAA 
ATTTTTAGAA ATACAGGTCA CAAAATAGAA ACAGACCTTC CCCAGATACG ATCGACCTTA 
ATTCCCATTT TACATCAAAA AGCAAAGAGG GGTACTCCAC ACCAAGCAAA ACAGGCTGTG 
CACTGTATAC ACGCCATATT CACAAATAAA GAAGTCCAGC TTGCACAGAT TTTTGAGCCA 
CTCAGTAGGA GTCTGAATGC TGATGTGCCA GAACAACTTA TAACTCCATT AGTTTCATTG 
GGCCACATTT CTATGTTAGC ACCAGATCAG TTTGCTTCCC CAATGAAATC TGTAGTAGCA 
AATTTTATTG TGAAAGATCT GCTAATGAAT GACAGGTCAA CAGGTGAAAA GAATGGAAAA 
CTGTGGTCTC CAGATGAAGA GGTTTCCCCT GAAGTACTAG CAAAGGTACA GGCAATTAAA 
CTTCTGGTAA GGTGGCTGTT GGGTATGAAA AACAACCAGT CTAAATCTGC CAATTCAACC 
CTTCGGTTAT TATCAGCGAT GTTGGTTAGT GAGGGTGACC TGACAGAGCA AAAGAGGATC 
AGTAAATCTG ATATGTCTCG CTTGCGATTA GCTGCTGGTA GTGCCATAAT GAAGCTTGCT 
CAGGAACCTT GTTACCATGA AATTATTACC CCAGAACAGT TTCAGCTCTG TGCACTTGTT 
ATTAATGATG AGTGTTACCA AGTAAGGCAG ATATTTGCTC AGAAGCTGCA TAAGGCACTT 
GTGAAGTTAC TGCTCCCATT GGAGTATATG GCGATCTTTG CCTTGTGTGC CAAAGATCCT 
GTGAAGGAGA GAAGAGCACA CGCACGACAA TGTTTACTGA AAAATATCAG TATACGCAGG 
GAATACATTA AGCAGAATCC TATGGCTACT GAGAAATTAT TATCACTGTT GCCTGAATAT 
GTAGTTCCAT ACATGATTCA CCTGCTAGCC CATGATCCAG ATTTTACAAG ATCACAAGAT 
GTTGATCAGC TTCGTGATAT CAAAGAGTGC CTATGGTTCA TGCTTGAAGT TTTAATGACA 
AAGAATGAAA ACAATAGCCA TGCCTTTATG AAGAAGATGG CAGAGAACAT CAAGTTAACC 
AGAGATGCCC AGTCTCCAGA TGAATCCAAG ACAAATGAAA AACTGTATAC AGTATGTGAT 
GTGGCTCTCT GTGTTATAAA TAGTAAAAGT GCTTTGTGCA ATGCAGATTC ACCAAAGGAC 
CCAGTCCTCC CAATGAAATT TTTTACACAA CCTGAAAAGG ACTTCTGTAA CGATAAGAGT 
TATATTTCAG AAGAGACAAG AGTACTTCTG TTAACAGGAA AGCCAAAGCC TGCTGGAGTA 
CTAGGTGCAG TAAATAAGCC TTTATCAGCA ACGGGAAGGA AACCCTATGT TAGAAGCACT 
GGCACTGAGA CTGGAAGCAA TATTAATGTA AATTCAGAGC TGAACCCTTC AACCGGAAAT 
CGATCAAGGG AACAGAGTTC AGAGGCAGCA GAAACTGGAG TTAGTGAAAA TGAAGAGAAC 
CCTGTGAGGA TTATTTCAGT CACACCTGTA AAGAATATTG ACCCAGTAAA GAATAAGGAA 
ATTAATTCTG ATCAGGCTAC CCAGGGCAAC ATCAGCAGTG ACCGAGGAAA GAAAAGAACA 
GTAACAGCAG CTGGTGCAGA GAATATCCAA CAAAAAACAG ATGAGAAAGT AGATGAATCG 
GGACCTCCCG CCCCTTCCAA ACCCAGGAGA GGACGTCGAC CCAAGTCTGA ATCTCAGGGC 
AATGCTACCA AAAATGATGA TCTAAATAAA CCTATTAACA AGGGAAGGAA GAGAGCTGCA 
GTGGGTCAGG AGAGCCCTGG GGGTTTGGAA GCAGGTAATG CCAAAGCACC CAAACTGCAA 
GATTTAGCCA AAAAGGCAGC ACCAGCAGAA AGACAAATTG ACTTACAAAG GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins.
The EMBO journal36(24)3573-3599(2017 12)
Wutz G,V?rnai C,Nagasaka K,Cisneros DA,Stocsits RR,Tang W,Schoenfelder S,Jessberger G,Muhar M,Hossain MJ,Walther N,Koch B,Kueblbeck M,Ellenberg J,Zuber J,Fraser P,Peters JM

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Higher Order Chromatin Modulator Cohesin SA1 Is an Early Biomarker for Colon Carcinogenesis: Race-Specific Implications.
Cancer prevention research (Philadelphia, Pa.)9(11)844-854(2016 Nov)
Wali RK,Momi N,Dela Cruz M,Calderwood AH,Stypula-Cyrus Y,Almassalha L,Chhaparia A,Weber CR,Radosevich A,Tiwari AK,Latif B,Backman V,Roy HK

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Cell163(3)712-23(2015 Oct)
Hein MY,Hubner NC,Poser I,Cox J,Nagaraj N,Toyoda Y,Gak IA,Weisswange I,Mansfeld J,Buchholz F,Hyman AA,Mann M

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PDS5A cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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