RHOBTB2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RHOBTB2
Entrez Gene ID	23221
Full Name	Rho related BTB domain containing 2
Synonyms	DBC2
General protein information	Preferred Names Rho related BTB domain containing 2 Names rho-related BTB domain-containing protein 2 deleted in breast cancer 2 gene protein p83
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8p21.3
Summary	The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
Disorder MIM:	607352

mRNA and Protein(s)

mRNA	Protein	Name
NM_001374791.1	NP_001361720.1	rho-related BTB domain-containing protein 2 isoform 3
NM_015178.2	NP_055993.2	rho-related BTB domain-containing protein 2 isoform 3
NM_001160036.2	NP_001153508.1	rho-related BTB domain-containing protein 2 isoform 1
XM_017013251.1	XP_016868740.1	rho-related BTB domain-containing protein 2 isoform X1
NM_001160037.1	NP_001153509.1	rho-related BTB domain-containing protein 2 isoform 2
NM_001160037.2	NP_001153509.1	rho-related BTB domain-containing protein 2 isoform 2
NM_015178.3	NP_055993.2	rho-related BTB domain-containing protein 2 isoform 3
NM_001160036.1	NP_001153508.1	rho-related BTB domain-containing protein 2 isoform 1

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	rhobtb2	XP_002932752.2
	RHOBTB2	XP_001107431.2
Pan troglodytes (chimpanzee)	RHOBTB2	XP_003311691.1
Mus musculus (house mouse)	Rhobtb2	NP_705734.4
Danio rerio (zebrafish)	rhobtb2b	XP_694198.5
Bos taurus (cattle)	RHOBTB2	NP_001096574.1
Rattus norvegicus (Norway rat)	Rhobtb2	NP_001013151.1
Gallus gallus (chicken)	RHOBTB2	XP_001232710.3
Drosophila melanogaster (fruit fly)	RhoBTB	NP_001262108.1
Homo sapiens (human)	RHOBTB2	NP_001153508.1
Canis lupus familiaris (dog)	RHOBTB2	XP_005635764.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006474	XP_316514.4

Gene Ontology
Bibliography

Related articles in PubMed

Missense Variants in RHOBTB2 Cause a Developmental and Epileptic Encephalopathy in Humans, and Altered Levels Cause Neurological Defects in Drosophila.
Straub J, Konrad EDH, Gr?ner J, Toutain A, Bok LA, Cho MT, Crawford HP, Dubbs H, Douglas G, Jobling R, Johnson D, Krock B, Mikati MA, Nesbitt A, Nicolai J, Phillips M, Poduri A, Ortiz-Gonzalez XR, Powis Z, Santani A, Smith L, Stegmann APA, Stumpel C, Vreeburg M, , Fliedner A, Gregor A, Sticht H, Zweier C
American journal of human genetics102(1)44-57(2018 Jan)

DBC2/RhoBTB2 functions as a tumor suppressor protein via Musashi-2 ubiquitination in breast cancer.
Choi YM, Kim KB, Lee JH, Chun YK, An IS, An S, Bae S
Oncogene36(20)2802-2812(2017 May)

Atypical Rho GTPases of the RhoBTB Subfamily: Roles in Vesicle Trafficking and Tumorigenesis.
Ji W, Rivero F
Cells5(2)(2016 Jun)

Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants.
Prince TL, Kijima T, Tatokoro M, Lee S, Tsutsumi S, Yim K, Rivas C, Alarcon S, Schwartz H, Khamit-Kush K, Scroggins BT, Beebe K, Trepel JB, Neckers L
PloS one10(10)e0141786(2015)

Hsp90-dependent assembly of the DBC2/RhoBTB2-Cullin3 E3-ligase complex.
Manjarrez JR, Sun L, Prince T, Matts RL
PloS one9(3)e90054(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

these findings provide evidence that DBC2 suppresses tumorigenesis in breast cancer by ubiquitinating MSI2.
Title: DBC2/RhoBTB2 functions as a tumor suppressor protein via Musashi-2 ubiquitination in breast cancer.

Mutation in the promoter and exon 7 of DBC2 gene is not common in the Chinese population and may not contribute to the susceptibility for breast cancer in China
Title: The mutation of DBC2 in breast cancer patients from the Han ethnic group in Eastern China.

). The results demonstrated that aberrant methylation of RhoBTB2 may be responsible for the suppression of RhoBTB2 mRNA expression in breast cancer, a significant event during the genesis of breast cancer that correlated with progesterone receptor status
Title: RhoBTB2 gene in breast cancer is silenced by promoter methylation.

data suggest a new paradigm for Hsp90-modulated assembly of a Cul3/DBC2 E3 ubiquitin ligase complex that may extend to other E3 ligase complexes.
Title: Hsp90-dependent assembly of the DBC2/RhoBTB2-Cullin3 E3-ligase complex.

Thus loss of DBC2 expression is caused by abnormal methylation of DBC2 and might have a role in breast cancer development.
Title: Decreased expression of the DBC2 gene and its clinicopathological significance in breast cancer: correlation with aberrant DNA methylation.

The following RHOBTB2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RHOBTB2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu03085	NM_001160036.2 Latest version!	Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu03085	XM_017013251.1 Latest version!	Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu31667	NM_001374791.1 Latest version!	Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu31667	NM_015178.3 Latest version!	Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu31989	NM_001160037.2 Latest version!	Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OHu31989	NM_001160037.1	Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$517.30 $739.00
OHu31667	NM_015178.2	Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu03085	NM_001160036.1	Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RHOBTB2 ( NM_001160036.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001153508.1 Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu03085
Clone ID Related Accession (Same CDS sequence)	NM_001160036.2 , XM_017013251.1 , NM_001160036.1
Accession Version	NM_001160036.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2250bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-14
Organism	Homo sapiens(human)
Product	rho-related BTB domain-containing protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC107959.8, BC034917.1, AK292863.1, AB018260.2, AA641575.1, AY009093.1 and BG255120.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_001160036.1. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.2490859.1, BC034917.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAAGCCT GGAGAAAAGG CCCCGATGGC CCCCAGAAGA CCTCTTCAGA CAGCATGTCC 
CGTTTAATGG ATTCTGACAT GGATTATGAA AGGCCAAACG TAGAGACCAT CAAGTGCGTT 
GTGGTGGGGG ACAACGCCGT GGGTAAGACC AGGCTCATCT GTGCCCGCGC TTGCAATGCC 
ACCCTCACCC AGTACCAGCT GCTGGCCACG CATGTGCCCA CAGTATGGGC CATCGACCAA 
TATCGTGTGT GCCAGGAGGT GCTGGAACGC TCCCGAGACG TGGTAGATGA TGTCAGCGTC 
TCTCTGCGCC TCTGGGACAC CTTTGGAGAC CACCACAAAG ACCGTCGCTT TGCTTATGGG 
AGATCTGATG TGGTGGTTCT GTGCTTCTCC ATTGCCAACC CCAATTCCCT CCACCATGTC 
AAGACCATGT GGTACCCAGA AATCAAGCAC TTCTGCCCCC GAGCACCTGT CATCTTGGTG 
GGCTGCCAGT TGGACCTGCG CTACGCTGAC CTGGAGGCTG TCAACAGGGC TAGGCGACCC 
TTGGCTAGGC CCATCAAACC TAATGAAATC CTGCCCCCAG AGAAGGGTCG GGAGGTGGCC 
AAGGAGCTGG GCATCCCCTA CTATGAGACC AGCGTGGTGG CCCAGTTCGG CATCAAGGAC 
GTCTTTGACA ACGCCATCCG AGCTGCACTC ATCTCCCGCC GCCACCTGCA GTTCTGGAAG 
TCCCACCTCC GCAATGTGCA GCGGCCTCTG CTGCAGGCAC CCTTCCTACC CCCCAAGCCA 
CCGCCCCCGA TCATCGTGGT GCCCGACCCT CCCTCCAGCA GCGAGGAGTG CCCCGCCCAC 
CTCCTGGAGG ACCCGCTCTG CGCGGACGTC ATCCTGGTGC TGCAGGAGCG GGTGCGCATC 
TTTGCCCACA AGATCTACCT CTCCACCTCT TCCTCCAAGT TCTATGACCT GTTCCTCATG 
GACCTGAGTG AGGGGGAGCT GGGGGGCCCC TCGGAGCCAG GGGGCACCCA CCCAGAGGAC 
CACCAGGGCC ACTCTGATCA ACACCACCAC CATCACCACC ACCACCATGG GCGAGACTTC 
CTGCTCCGAG CAGCCAGCTT TGACGTGTGC GAGAGCGTGG ATGAGGCTGG GGGCTCCGGT 
CCTGCTGGCC TCCGTGCTTC CACCAGCGAC GGGATCTTAC GGGGCAACGG AACAGGGTAC 
CTACCGGGCA GGGGTCGTGT GCTGTCTTCC TGGAGCCGAG CTTTTGTGAG CATCCAGGAA 
GAGATGGCAG AAGATCCTCT CACCTACAAA TCCCGGCTGA TGGTGGTGGT GAAGATGGAC 
AGTTCCATCC AGCCGGGGCC CTTCCGGGCT GTCCTCAAGT ACCTGTACAC GGGGGAGCTA 
GATGAGAACG AGCGTGACCT CATGCACATT GCCCACATTG CTGAGCTGCT CGAGGTCTTT 
GATCTGCGCA TGATGGTGGC CAACATTCTC AACAATGAGG CCTTCATGAA CCAGGAGATC 
ACCAAGGCCT TCCACGTCCG CCGGACCAAC CGGGTTAAGG AGTGCTTGGC AAAAGGCACC 
TTCTCAGATG TGACCTTCAT CCTGGATGAT GGCACCATCA GCGCCCACAA GCCCCTGTTG 
ATTTCCAGCT GTGACTGGAT GGCTGCCATG TTTGGGGGGC CATTTGTGGA GAGCTCCACC 
CGGGAGGTGG TGTTTCCCTA CACAAGCAAG AGCTGCATGC GGGCCGTGCT GGAATACCTC 
TACACCGGCA TGTTCACCTC CAGCCCCGAC CTGGATGACA TGAAGCTCAT CATTCTAGCC 
AACCGCCTCT GCCTGCCACA CCTGGTTGCC CTCACAGAGC AGTACACAGT GACCGGGCTG 
ATGGAAGCGA CCCAGATGAT GGTGGACATC GATGGGGACG TCCTTGTGTT CCTGGAACTG 
GCTCAGTTCC ACTGTGCGTA CCAGCTGGCC GACTGGTGTC TCCACCACAT CTGCACCAAC 
TACAACAACG TGTGCCGCAA GTTCCCCCGA GACATGAAGG CCATGTCCCC AGAAAACCAG 
GAGTATTTCG AGAAGCATCG GTGGCCACCT GTGTGGTACC TGAAGGAGGA AGATCATTAC 
CAGCGGGCAC GGAAGGAGCG TGAGAAGGAG GACTACCTCC ACCTCAAGCG GCAGCCCAAA 
CGGCGTTGGC TCTTCTGGAA CAGTCCATCC TCCCCGTCTT CCTCGGCAGC CTCCTCCTCA 
TCCCCATCTT CCTCCTCGGC TGTGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001153508.1
CDS	450..2699
Translation	MQAWRKGPDGPQKTSSDSMSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSPSSSSAVV

Target ORF information:

RefSeq Version	NM_001160036.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001160036.2

ORF Insert Sequence:

ATGCAAGCCT GGAGAAAAGG CCCCGATGGC CCCCAGAAGA CCTCTTCAGA CAGCATGTCC 
CGTTTAATGG ATTCTGACAT GGATTATGAA AGGCCAAACG TAGAGACCAT CAAGTGCGTT 
GTGGTGGGGG ACAACGCCGT GGGTAAGACC AGGCTCATCT GTGCCCGCGC TTGCAATGCC 
ACCCTCACCC AGTACCAGCT GCTGGCCACG CATGTGCCCA CAGTATGGGC CATCGACCAA 
TATCGTGTGT GCCAGGAGGT GCTGGAACGC TCCCGAGACG TGGTAGATGA TGTCAGCGTC 
TCTCTGCGCC TCTGGGACAC CTTTGGAGAC CACCACAAAG ACCGTCGCTT TGCTTATGGG 
AGATCTGATG TGGTGGTTCT GTGCTTCTCC ATTGCCAACC CCAATTCCCT CCACCATGTC 
AAGACCATGT GGTACCCAGA AATCAAGCAC TTCTGCCCCC GAGCACCTGT CATCTTGGTG 
GGCTGCCAGT TGGACCTGCG CTACGCTGAC CTGGAGGCTG TCAACAGGGC TAGGCGACCC 
TTGGCTAGGC CCATCAAACC TAATGAAATC CTGCCCCCAG AGAAGGGTCG GGAGGTGGCC 
AAGGAGCTGG GCATCCCCTA CTATGAGACC AGCGTGGTGG CCCAGTTCGG CATCAAGGAC 
GTCTTTGACA ACGCCATCCG AGCTGCACTC ATCTCCCGCC GCCACCTGCA GTTCTGGAAG 
TCCCACCTCC GCAATGTGCA GCGGCCTCTG CTGCAGGCAC CCTTCCTACC CCCCAAGCCA 
CCGCCCCCGA TCATCGTGGT GCCCGACCCT CCCTCCAGCA GCGAGGAGTG CCCCGCCCAC 
CTCCTGGAGG ACCCGCTCTG CGCGGACGTC ATCCTGGTGC TGCAGGAGCG GGTGCGCATC 
TTTGCCCACA AGATCTACCT CTCCACCTCT TCCTCCAAGT TCTATGACCT GTTCCTCATG 
GACCTGAGTG AGGGGGAGCT GGGGGGCCCC TCGGAGCCAG GGGGCACCCA CCCAGAGGAC 
CACCAGGGCC ACTCTGATCA ACACCACCAC CATCACCACC ACCACCATGG GCGAGACTTC 
CTGCTCCGAG CAGCCAGCTT TGACGTGTGC GAGAGCGTGG ATGAGGCTGG GGGCTCCGGT 
CCTGCTGGCC TCCGTGCTTC CACCAGCGAC GGGATCTTAC GGGGCAACGG AACAGGGTAC 
CTACCGGGCA GGGGTCGTGT GCTGTCTTCC TGGAGCCGAG CTTTTGTGAG CATCCAGGAA 
GAGATGGCAG AAGATCCTCT CACCTACAAA TCCCGGCTGA TGGTGGTGGT GAAGATGGAC 
AGTTCCATCC AGCCGGGGCC CTTCCGGGCT GTCCTCAAGT ACCTGTACAC GGGGGAGCTA 
GATGAGAACG AGCGTGACCT CATGCACATT GCCCACATTG CTGAGCTGCT CGAGGTCTTT 
GATCTGCGCA TGATGGTGGC CAACATTCTC AACAATGAGG CCTTCATGAA CCAGGAGATC 
ACCAAGGCCT TCCACGTCCG CCGGACCAAC CGGGTTAAGG AGTGCTTGGC AAAAGGCACC 
TTCTCAGATG TGACCTTCAT CCTGGATGAT GGCACCATCA GCGCCCACAA GCCCCTGTTG 
ATTTCCAGCT GTGACTGGAT GGCTGCCATG TTTGGGGGGC CATTTGTGGA GAGCTCCACC 
CGGGAGGTGG TGTTTCCCTA CACAAGCAAG AGCTGCATGC GGGCCGTGCT GGAATACCTC 
TACACCGGCA TGTTCACCTC CAGCCCCGAC CTGGATGACA TGAAGCTCAT CATTCTAGCC 
AACCGCCTCT GCCTGCCACA CCTGGTTGCC CTCACAGAGC AGTACACAGT GACCGGGCTG 
ATGGAAGCGA CCCAGATGAT GGTGGACATC GATGGGGACG TCCTTGTGTT CCTGGAACTG 
GCTCAGTTCC ACTGTGCGTA CCAGCTGGCC GACTGGTGTC TCCACCACAT CTGCACCAAC 
TACAACAACG TGTGCCGCAA GTTCCCCCGA GACATGAAGG CCATGTCCCC AGAAAACCAG 
GAGTATTTCG AGAAGCATCG GTGGCCACCT GTGTGGTACC TGAAGGAGGA AGATCATTAC 
CAGCGGGCAC GGAAGGAGCG TGAGAAGGAG GACTACCTCC ACCTCAAGCG GCAGCCCAAA 
CGGCGTTGGC TCTTCTGGAA CAGTCCATCC TCCCCGTCTT CCTCGGCAGC CTCCTCCTCA 
TCCCCATCTT CCTCCTCGGC TGTGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RHOBTB2 ( NM_001160036.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001153508.1 Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu03085
Clone ID Related Accession (Same CDS sequence)	NM_001160036.2 , XM_017013251.1 , NM_001160036.1
Accession Version	NM_001160036.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2250bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-22
Organism	Homo sapiens(human)
Product	rho-related BTB domain-containing protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC034917.1, AK292863.1, AB018260.2, AA641575.1, AY009093.1 and BG255120.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC034917.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAAGCCT GGAGAAAAGG CCCCGATGGC CCCCAGAAGA CCTCTTCAGA CAGCATGTCC 
CGTTTAATGG ATTCTGACAT GGATTATGAA AGGCCAAACG TAGAGACCAT CAAGTGCGTT 
GTGGTGGGGG ACAACGCCGT GGGTAAGACC AGGCTCATCT GTGCCCGCGC TTGCAATGCC 
ACCCTCACCC AGTACCAGCT GCTGGCCACG CATGTGCCCA CAGTATGGGC CATCGACCAA 
TATCGTGTGT GCCAGGAGGT GCTGGAACGC TCCCGAGACG TGGTAGATGA TGTCAGCGTC 
TCTCTGCGCC TCTGGGACAC CTTTGGAGAC CACCACAAAG ACCGTCGCTT TGCTTATGGG 
AGATCTGATG TGGTGGTTCT GTGCTTCTCC ATTGCCAACC CCAATTCCCT CCACCATGTC 
AAGACCATGT GGTACCCAGA AATCAAGCAC TTCTGCCCCC GAGCACCTGT CATCTTGGTG 
GGCTGCCAGT TGGACCTGCG CTACGCTGAC CTGGAGGCTG TCAACAGGGC TAGGCGACCC 
TTGGCTAGGC CCATCAAACC TAATGAAATC CTGCCCCCAG AGAAGGGTCG GGAGGTGGCC 
AAGGAGCTGG GCATCCCCTA CTATGAGACC AGCGTGGTGG CCCAGTTCGG CATCAAGGAC 
GTCTTTGACA ACGCCATCCG AGCTGCACTC ATCTCCCGCC GCCACCTGCA GTTCTGGAAG 
TCCCACCTCC GCAATGTGCA GCGGCCTCTG CTGCAGGCAC CCTTCCTACC CCCCAAGCCA 
CCGCCCCCGA TCATCGTGGT GCCCGACCCT CCCTCCAGCA GCGAGGAGTG CCCCGCCCAC 
CTCCTGGAGG ACCCGCTCTG CGCGGACGTC ATCCTGGTGC TGCAGGAGCG GGTGCGCATC 
TTTGCCCACA AGATCTACCT CTCCACCTCT TCCTCCAAGT TCTATGACCT GTTCCTCATG 
GACCTGAGTG AGGGGGAGCT GGGGGGCCCC TCGGAGCCAG GGGGCACCCA CCCAGAGGAC 
CACCAGGGCC ACTCTGATCA ACACCACCAC CATCACCACC ACCACCATGG GCGAGACTTC 
CTGCTCCGAG CAGCCAGCTT TGACGTGTGC GAGAGCGTGG ATGAGGCTGG GGGCTCCGGT 
CCTGCTGGCC TCCGTGCTTC CACCAGCGAC GGGATCTTAC GGGGCAACGG AACAGGGTAC 
CTACCGGGCA GGGGTCGTGT GCTGTCTTCC TGGAGCCGAG CTTTTGTGAG CATCCAGGAA 
GAGATGGCAG AAGATCCTCT CACCTACAAA TCCCGGCTGA TGGTGGTGGT GAAGATGGAC 
AGTTCCATCC AGCCGGGGCC CTTCCGGGCT GTCCTCAAGT ACCTGTACAC GGGGGAGCTA 
GATGAGAACG AGCGTGACCT CATGCACATT GCCCACATTG CTGAGCTGCT CGAGGTCTTT 
GATCTGCGCA TGATGGTGGC CAACATTCTC AACAATGAGG CCTTCATGAA CCAGGAGATC 
ACCAAGGCCT TCCACGTCCG CCGGACCAAC CGGGTTAAGG AGTGCTTGGC AAAAGGCACC 
TTCTCAGATG TGACCTTCAT CCTGGATGAT GGCACCATCA GCGCCCACAA GCCCCTGTTG 
ATTTCCAGCT GTGACTGGAT GGCTGCCATG TTTGGGGGGC CATTTGTGGA GAGCTCCACC 
CGGGAGGTGG TGTTTCCCTA CACAAGCAAG AGCTGCATGC GGGCCGTGCT GGAATACCTC 
TACACCGGCA TGTTCACCTC CAGCCCCGAC CTGGATGACA TGAAGCTCAT CATTCTAGCC 
AACCGCCTCT GCCTGCCACA CCTGGTTGCC CTCACAGAGC AGTACACAGT GACCGGGCTG 
ATGGAAGCGA CCCAGATGAT GGTGGACATC GATGGGGACG TCCTTGTGTT CCTGGAACTG 
GCTCAGTTCC ACTGTGCGTA CCAGCTGGCC GACTGGTGTC TCCACCACAT CTGCACCAAC 
TACAACAACG TGTGCCGCAA GTTCCCCCGA GACATGAAGG CCATGTCCCC AGAAAACCAG 
GAGTATTTCG AGAAGCATCG GTGGCCACCT GTGTGGTACC TGAAGGAGGA AGATCATTAC 
CAGCGGGCAC GGAAGGAGCG TGAGAAGGAG GACTACCTCC ACCTCAAGCG GCAGCCCAAA 
CGGCGTTGGC TCTTCTGGAA CAGTCCATCC TCCCCGTCTT CCTCGGCAGC CTCCTCCTCA 
TCCCCATCTT CCTCCTCGGC TGTGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001153508.1
CDS	284..2533
Translation	MQAWRKGPDGPQKTSSDSMSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSPSSSSAVV

Target ORF information:

RefSeq Version	NM_001160036.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001160036.1

ORF Insert Sequence:

ATGCAAGCCT GGAGAAAAGG CCCCGATGGC CCCCAGAAGA CCTCTTCAGA CAGCATGTCC 
CGTTTAATGG ATTCTGACAT GGATTATGAA AGGCCAAACG TAGAGACCAT CAAGTGCGTT 
GTGGTGGGGG ACAACGCCGT GGGTAAGACC AGGCTCATCT GTGCCCGCGC TTGCAATGCC 
ACCCTCACCC AGTACCAGCT GCTGGCCACG CATGTGCCCA CAGTATGGGC CATCGACCAA 
TATCGTGTGT GCCAGGAGGT GCTGGAACGC TCCCGAGACG TGGTAGATGA TGTCAGCGTC 
TCTCTGCGCC TCTGGGACAC CTTTGGAGAC CACCACAAAG ACCGTCGCTT TGCTTATGGG 
AGATCTGATG TGGTGGTTCT GTGCTTCTCC ATTGCCAACC CCAATTCCCT CCACCATGTC 
AAGACCATGT GGTACCCAGA AATCAAGCAC TTCTGCCCCC GAGCACCTGT CATCTTGGTG 
GGCTGCCAGT TGGACCTGCG CTACGCTGAC CTGGAGGCTG TCAACAGGGC TAGGCGACCC 
TTGGCTAGGC CCATCAAACC TAATGAAATC CTGCCCCCAG AGAAGGGTCG GGAGGTGGCC 
AAGGAGCTGG GCATCCCCTA CTATGAGACC AGCGTGGTGG CCCAGTTCGG CATCAAGGAC 
GTCTTTGACA ACGCCATCCG AGCTGCACTC ATCTCCCGCC GCCACCTGCA GTTCTGGAAG 
TCCCACCTCC GCAATGTGCA GCGGCCTCTG CTGCAGGCAC CCTTCCTACC CCCCAAGCCA 
CCGCCCCCGA TCATCGTGGT GCCCGACCCT CCCTCCAGCA GCGAGGAGTG CCCCGCCCAC 
CTCCTGGAGG ACCCGCTCTG CGCGGACGTC ATCCTGGTGC TGCAGGAGCG GGTGCGCATC 
TTTGCCCACA AGATCTACCT CTCCACCTCT TCCTCCAAGT TCTATGACCT GTTCCTCATG 
GACCTGAGTG AGGGGGAGCT GGGGGGCCCC TCGGAGCCAG GGGGCACCCA CCCAGAGGAC 
CACCAGGGCC ACTCTGATCA ACACCACCAC CATCACCACC ACCACCATGG GCGAGACTTC 
CTGCTCCGAG CAGCCAGCTT TGACGTGTGC GAGAGCGTGG ATGAGGCTGG GGGCTCCGGT 
CCTGCTGGCC TCCGTGCTTC CACCAGCGAC GGGATCTTAC GGGGCAACGG AACAGGGTAC 
CTACCGGGCA GGGGTCGTGT GCTGTCTTCC TGGAGCCGAG CTTTTGTGAG CATCCAGGAA 
GAGATGGCAG AAGATCCTCT CACCTACAAA TCCCGGCTGA TGGTGGTGGT GAAGATGGAC 
AGTTCCATCC AGCCGGGGCC CTTCCGGGCT GTCCTCAAGT ACCTGTACAC GGGGGAGCTA 
GATGAGAACG AGCGTGACCT CATGCACATT GCCCACATTG CTGAGCTGCT CGAGGTCTTT 
GATCTGCGCA TGATGGTGGC CAACATTCTC AACAATGAGG CCTTCATGAA CCAGGAGATC 
ACCAAGGCCT TCCACGTCCG CCGGACCAAC CGGGTTAAGG AGTGCTTGGC AAAAGGCACC 
TTCTCAGATG TGACCTTCAT CCTGGATGAT GGCACCATCA GCGCCCACAA GCCCCTGTTG 
ATTTCCAGCT GTGACTGGAT GGCTGCCATG TTTGGGGGGC CATTTGTGGA GAGCTCCACC 
CGGGAGGTGG TGTTTCCCTA CACAAGCAAG AGCTGCATGC GGGCCGTGCT GGAATACCTC 
TACACCGGCA TGTTCACCTC CAGCCCCGAC CTGGATGACA TGAAGCTCAT CATTCTAGCC 
AACCGCCTCT GCCTGCCACA CCTGGTTGCC CTCACAGAGC AGTACACAGT GACCGGGCTG 
ATGGAAGCGA CCCAGATGAT GGTGGACATC GATGGGGACG TCCTTGTGTT CCTGGAACTG 
GCTCAGTTCC ACTGTGCGTA CCAGCTGGCC GACTGGTGTC TCCACCACAT CTGCACCAAC 
TACAACAACG TGTGCCGCAA GTTCCCCCGA GACATGAAGG CCATGTCCCC AGAAAACCAG 
GAGTATTTCG AGAAGCATCG GTGGCCACCT GTGTGGTACC TGAAGGAGGA AGATCATTAC 
CAGCGGGCAC GGAAGGAGCG TGAGAAGGAG GACTACCTCC ACCTCAAGCG GCAGCCCAAA 
CGGCGTTGGC TCTTCTGGAA CAGTCCATCC TCCCCGTCTT CCTCGGCAGC CTCCTCCTCA 
TCCCCATCTT CCTCCTCGGC TGTGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RHOBTB2 ( XM_017013251.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016868740.1 Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant X1, mRNA.

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CloneID	OHu03085
Clone ID Related Accession (Same CDS sequence)	NM_001160036.2 , XM_017013251.1 , NM_001160036.1
Accession Version	XM_017013251.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2250bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	rho-related BTB domain-containing protein 2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAAGCCT GGAGAAAAGG CCCCGATGGC CCCCAGAAGA CCTCTTCAGA CAGCATGTCC 
CGTTTAATGG ATTCTGACAT GGATTATGAA AGGCCAAACG TAGAGACCAT CAAGTGCGTT 
GTGGTGGGGG ACAACGCCGT GGGTAAGACC AGGCTCATCT GTGCCCGCGC TTGCAATGCC 
ACCCTCACCC AGTACCAGCT GCTGGCCACG CATGTGCCCA CAGTATGGGC CATCGACCAA 
TATCGTGTGT GCCAGGAGGT GCTGGAACGC TCCCGAGACG TGGTAGATGA TGTCAGCGTC 
TCTCTGCGCC TCTGGGACAC CTTTGGAGAC CACCACAAAG ACCGTCGCTT TGCTTATGGG 
AGATCTGATG TGGTGGTTCT GTGCTTCTCC ATTGCCAACC CCAATTCCCT CCACCATGTC 
AAGACCATGT GGTACCCAGA AATCAAGCAC TTCTGCCCCC GAGCACCTGT CATCTTGGTG 
GGCTGCCAGT TGGACCTGCG CTACGCTGAC CTGGAGGCTG TCAACAGGGC TAGGCGACCC 
TTGGCTAGGC CCATCAAACC TAATGAAATC CTGCCCCCAG AGAAGGGTCG GGAGGTGGCC 
AAGGAGCTGG GCATCCCCTA CTATGAGACC AGCGTGGTGG CCCAGTTCGG CATCAAGGAC 
GTCTTTGACA ACGCCATCCG AGCTGCACTC ATCTCCCGCC GCCACCTGCA GTTCTGGAAG 
TCCCACCTCC GCAATGTGCA GCGGCCTCTG CTGCAGGCAC CCTTCCTACC CCCCAAGCCA 
CCGCCCCCGA TCATCGTGGT GCCCGACCCT CCCTCCAGCA GCGAGGAGTG CCCCGCCCAC 
CTCCTGGAGG ACCCGCTCTG CGCGGACGTC ATCCTGGTGC TGCAGGAGCG GGTGCGCATC 
TTTGCCCACA AGATCTACCT CTCCACCTCT TCCTCCAAGT TCTATGACCT GTTCCTCATG 
GACCTGAGTG AGGGGGAGCT GGGGGGCCCC TCGGAGCCAG GGGGCACCCA CCCAGAGGAC 
CACCAGGGCC ACTCTGATCA ACACCACCAC CATCACCACC ACCACCATGG GCGAGACTTC 
CTGCTCCGAG CAGCCAGCTT TGACGTGTGC GAGAGCGTGG ATGAGGCTGG GGGCTCCGGT 
CCTGCTGGCC TCCGTGCTTC CACCAGCGAC GGGATCTTAC GGGGCAACGG AACAGGGTAC 
CTACCGGGCA GGGGTCGTGT GCTGTCTTCC TGGAGCCGAG CTTTTGTGAG CATCCAGGAA 
GAGATGGCAG AAGATCCTCT CACCTACAAA TCCCGGCTGA TGGTGGTGGT GAAGATGGAC 
AGTTCCATCC AGCCGGGGCC CTTCCGGGCT GTCCTCAAGT ACCTGTACAC GGGGGAGCTA 
GATGAGAACG AGCGTGACCT CATGCACATT GCCCACATTG CTGAGCTGCT CGAGGTCTTT 
GATCTGCGCA TGATGGTGGC CAACATTCTC AACAATGAGG CCTTCATGAA CCAGGAGATC 
ACCAAGGCCT TCCACGTCCG CCGGACCAAC CGGGTTAAGG AGTGCTTGGC AAAAGGCACC 
TTCTCAGATG TGACCTTCAT CCTGGATGAT GGCACCATCA GCGCCCACAA GCCCCTGTTG 
ATTTCCAGCT GTGACTGGAT GGCTGCCATG TTTGGGGGGC CATTTGTGGA GAGCTCCACC 
CGGGAGGTGG TGTTTCCCTA CACAAGCAAG AGCTGCATGC GGGCCGTGCT GGAATACCTC 
TACACCGGCA TGTTCACCTC CAGCCCCGAC CTGGATGACA TGAAGCTCAT CATTCTAGCC 
AACCGCCTCT GCCTGCCACA CCTGGTTGCC CTCACAGAGC AGTACACAGT GACCGGGCTG 
ATGGAAGCGA CCCAGATGAT GGTGGACATC GATGGGGACG TCCTTGTGTT CCTGGAACTG 
GCTCAGTTCC ACTGTGCGTA CCAGCTGGCC GACTGGTGTC TCCACCACAT CTGCACCAAC 
TACAACAACG TGTGCCGCAA GTTCCCCCGA GACATGAAGG CCATGTCCCC AGAAAACCAG 
GAGTATTTCG AGAAGCATCG GTGGCCACCT GTGTGGTACC TGAAGGAGGA AGATCATTAC 
CAGCGGGCAC GGAAGGAGCG TGAGAAGGAG GACTACCTCC ACCTCAAGCG GCAGCCCAAA 
CGGCGTTGGC TCTTCTGGAA CAGTCCATCC TCCCCGTCTT CCTCGGCAGC CTCCTCCTCA 
TCCCCATCTT CCTCCTCGGC TGTGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016868740.1
CDS	4799..7048
Translation	MQAWRKGPDGPQKTSSDSMSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSPSSSSAVV

Target ORF information:

RefSeq Version	XM_017013251.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013251.1

ORF Insert Sequence:

ATGCAAGCCT GGAGAAAAGG CCCCGATGGC CCCCAGAAGA CCTCTTCAGA CAGCATGTCC 
CGTTTAATGG ATTCTGACAT GGATTATGAA AGGCCAAACG TAGAGACCAT CAAGTGCGTT 
GTGGTGGGGG ACAACGCCGT GGGTAAGACC AGGCTCATCT GTGCCCGCGC TTGCAATGCC 
ACCCTCACCC AGTACCAGCT GCTGGCCACG CATGTGCCCA CAGTATGGGC CATCGACCAA 
TATCGTGTGT GCCAGGAGGT GCTGGAACGC TCCCGAGACG TGGTAGATGA TGTCAGCGTC 
TCTCTGCGCC TCTGGGACAC CTTTGGAGAC CACCACAAAG ACCGTCGCTT TGCTTATGGG 
AGATCTGATG TGGTGGTTCT GTGCTTCTCC ATTGCCAACC CCAATTCCCT CCACCATGTC 
AAGACCATGT GGTACCCAGA AATCAAGCAC TTCTGCCCCC GAGCACCTGT CATCTTGGTG 
GGCTGCCAGT TGGACCTGCG CTACGCTGAC CTGGAGGCTG TCAACAGGGC TAGGCGACCC 
TTGGCTAGGC CCATCAAACC TAATGAAATC CTGCCCCCAG AGAAGGGTCG GGAGGTGGCC 
AAGGAGCTGG GCATCCCCTA CTATGAGACC AGCGTGGTGG CCCAGTTCGG CATCAAGGAC 
GTCTTTGACA ACGCCATCCG AGCTGCACTC ATCTCCCGCC GCCACCTGCA GTTCTGGAAG 
TCCCACCTCC GCAATGTGCA GCGGCCTCTG CTGCAGGCAC CCTTCCTACC CCCCAAGCCA 
CCGCCCCCGA TCATCGTGGT GCCCGACCCT CCCTCCAGCA GCGAGGAGTG CCCCGCCCAC 
CTCCTGGAGG ACCCGCTCTG CGCGGACGTC ATCCTGGTGC TGCAGGAGCG GGTGCGCATC 
TTTGCCCACA AGATCTACCT CTCCACCTCT TCCTCCAAGT TCTATGACCT GTTCCTCATG 
GACCTGAGTG AGGGGGAGCT GGGGGGCCCC TCGGAGCCAG GGGGCACCCA CCCAGAGGAC 
CACCAGGGCC ACTCTGATCA ACACCACCAC CATCACCACC ACCACCATGG GCGAGACTTC 
CTGCTCCGAG CAGCCAGCTT TGACGTGTGC GAGAGCGTGG ATGAGGCTGG GGGCTCCGGT 
CCTGCTGGCC TCCGTGCTTC CACCAGCGAC GGGATCTTAC GGGGCAACGG AACAGGGTAC 
CTACCGGGCA GGGGTCGTGT GCTGTCTTCC TGGAGCCGAG CTTTTGTGAG CATCCAGGAA 
GAGATGGCAG AAGATCCTCT CACCTACAAA TCCCGGCTGA TGGTGGTGGT GAAGATGGAC 
AGTTCCATCC AGCCGGGGCC CTTCCGGGCT GTCCTCAAGT ACCTGTACAC GGGGGAGCTA 
GATGAGAACG AGCGTGACCT CATGCACATT GCCCACATTG CTGAGCTGCT CGAGGTCTTT 
GATCTGCGCA TGATGGTGGC CAACATTCTC AACAATGAGG CCTTCATGAA CCAGGAGATC 
ACCAAGGCCT TCCACGTCCG CCGGACCAAC CGGGTTAAGG AGTGCTTGGC AAAAGGCACC 
TTCTCAGATG TGACCTTCAT CCTGGATGAT GGCACCATCA GCGCCCACAA GCCCCTGTTG 
ATTTCCAGCT GTGACTGGAT GGCTGCCATG TTTGGGGGGC CATTTGTGGA GAGCTCCACC 
CGGGAGGTGG TGTTTCCCTA CACAAGCAAG AGCTGCATGC GGGCCGTGCT GGAATACCTC 
TACACCGGCA TGTTCACCTC CAGCCCCGAC CTGGATGACA TGAAGCTCAT CATTCTAGCC 
AACCGCCTCT GCCTGCCACA CCTGGTTGCC CTCACAGAGC AGTACACAGT GACCGGGCTG 
ATGGAAGCGA CCCAGATGAT GGTGGACATC GATGGGGACG TCCTTGTGTT CCTGGAACTG 
GCTCAGTTCC ACTGTGCGTA CCAGCTGGCC GACTGGTGTC TCCACCACAT CTGCACCAAC 
TACAACAACG TGTGCCGCAA GTTCCCCCGA GACATGAAGG CCATGTCCCC AGAAAACCAG 
GAGTATTTCG AGAAGCATCG GTGGCCACCT GTGTGGTACC TGAAGGAGGA AGATCATTAC 
CAGCGGGCAC GGAAGGAGCG TGAGAAGGAG GACTACCTCC ACCTCAAGCG GCAGCCCAAA 
CGGCGTTGGC TCTTCTGGAA CAGTCCATCC TCCCCGTCTT CCTCGGCAGC CTCCTCCTCA 
TCCCCATCTT CCTCCTCGGC TGTGGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RHOBTB2 ( NM_015178.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_055993.2 Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 3, mRNA.

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CloneID	OHu31667
Clone ID Related Accession (Same CDS sequence)	NM_001374791.1 , NM_015178.2 , NM_015178.3
Accession Version	NM_015178.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2184bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	rho-related BTB domain-containing protein 2 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB018260.2, AK292863.1, AA641575.1, AY009093.1 and BG255120.1. On May 15, 2009 this sequence version replaced NM_015178.1. Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (3) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB018260.2, AY009093.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGATTCTG ACATGGATTA TGAAAGGCCA AACGTAGAGA CCATCAAGTG CGTTGTGGTG 
GGGGACAACG CCGTGGGTAA GACCAGGCTC ATCTGTGCCC GCGCTTGCAA TGCCACCCTC 
ACCCAGTACC AGCTGCTGGC CACGCATGTG CCCACAGTAT GGGCCATCGA CCAATATCGT 
GTGTGCCAGG AGGTGCTGGA ACGCTCCCGA GACGTGGTAG ATGATGTCAG CGTCTCTCTG 
CGCCTCTGGG ACACCTTTGG AGACCACCAC AAAGACCGTC GCTTTGCTTA TGGGAGATCT 
GATGTGGTGG TTCTGTGCTT CTCCATTGCC AACCCCAATT CCCTCCACCA TGTCAAGACC 
ATGTGGTACC CAGAAATCAA GCACTTCTGC CCCCGAGCAC CTGTCATCTT GGTGGGCTGC 
CAGTTGGACC TGCGCTACGC TGACCTGGAG GCTGTCAACA GGGCTAGGCG ACCCTTGGCT 
AGGCCCATCA AACCTAATGA AATCCTGCCC CCAGAGAAGG GTCGGGAGGT GGCCAAGGAG 
CTGGGCATCC CCTACTATGA GACCAGCGTG GTGGCCCAGT TCGGCATCAA GGACGTCTTT 
GACAACGCCA TCCGAGCTGC ACTCATCTCC CGCCGCCACC TGCAGTTCTG GAAGTCCCAC 
CTCCGCAATG TGCAGCGGCC TCTGCTGCAG GCACCCTTCC TACCCCCCAA GCCACCGCCC 
CCGATCATCG TGGTGCCCGA CCCTCCCTCC AGCAGCGAGG AGTGCCCCGC CCACCTCCTG 
GAGGACCCGC TCTGCGCGGA CGTCATCCTG GTGCTGCAGG AGCGGGTGCG CATCTTTGCC 
CACAAGATCT ACCTCTCCAC CTCTTCCTCC AAGTTCTATG ACCTGTTCCT CATGGACCTG 
AGTGAGGGGG AGCTGGGGGG CCCCTCGGAG CCAGGGGGCA CCCACCCAGA GGACCACCAG 
GGCCACTCTG ATCAACACCA CCACCATCAC CACCACCACC ATGGGCGAGA CTTCCTGCTC 
CGAGCAGCCA GCTTTGACGT GTGCGAGAGC GTGGATGAGG CTGGGGGCTC CGGTCCTGCT 
GGCCTCCGTG CTTCCACCAG CGACGGGATC TTACGGGGCA ACGGAACAGG GTACCTACCG 
GGCAGGGGTC GTGTGCTGTC TTCCTGGAGC CGAGCTTTTG TGAGCATCCA GGAAGAGATG 
GCAGAAGATC CTCTCACCTA CAAATCCCGG CTGATGGTGG TGGTGAAGAT GGACAGTTCC 
ATCCAGCCGG GGCCCTTCCG GGCTGTCCTC AAGTACCTGT ACACGGGGGA GCTAGATGAG 
AACGAGCGTG ACCTCATGCA CATTGCCCAC ATTGCTGAGC TGCTCGAGGT CTTTGATCTG 
CGCATGATGG TGGCCAACAT TCTCAACAAT GAGGCCTTCA TGAACCAGGA GATCACCAAG 
GCCTTCCACG TCCGCCGGAC CAACCGGGTT AAGGAGTGCT TGGCAAAAGG CACCTTCTCA 
GATGTGACCT TCATCCTGGA TGATGGCACC ATCAGCGCCC ACAAGCCCCT GTTGATTTCC 
AGCTGTGACT GGATGGCTGC CATGTTTGGG GGGCCATTTG TGGAGAGCTC CACCCGGGAG 
GTGGTGTTTC CCTACACAAG CAAGAGCTGC ATGCGGGCCG TGCTGGAATA CCTCTACACC 
GGCATGTTCA CCTCCAGCCC CGACCTGGAT GACATGAAGC TCATCATTCT AGCCAACCGC 
CTCTGCCTGC CACACCTGGT TGCCCTCACA GAGCAGTACA CAGTGACCGG GCTGATGGAA 
GCGACCCAGA TGATGGTGGA CATCGATGGG GACGTCCTTG TGTTCCTGGA ACTGGCTCAG 
TTCCACTGTG CGTACCAGCT GGCCGACTGG TGTCTCCACC ACATCTGCAC CAACTACAAC 
AACGTGTGCC GCAAGTTCCC CCGAGACATG AAGGCCATGT CCCCAGAAAA CCAGGAGTAT 
TTCGAGAAGC ATCGGTGGCC ACCTGTGTGG TACCTGAAGG AGGAAGATCA TTACCAGCGG 
GCACGGAAGG AGCGTGAGAA GGAGGACTAC CTCCACCTCA AGCGGCAGCC CAAACGGCGT 
TGGCTCTTCT GGAACAGTCC ATCCTCCCCG TCTTCCTCGG CAGCCTCCTC CTCATCCCCA 
TCTTCCTCCT CGGCTGTGGT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055993.2
CDS	538..2721
Translation	MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSPSSSSAVV

Target ORF information:

RefSeq Version	NM_015178.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015178.2

ORF Insert Sequence:

ATGGATTCTG ACATGGATTA TGAAAGGCCA AACGTAGAGA CCATCAAGTG CGTTGTGGTG 
GGGGACAACG CCGTGGGTAA GACCAGGCTC ATCTGTGCCC GCGCTTGCAA TGCCACCCTC 
ACCCAGTACC AGCTGCTGGC CACGCATGTG CCCACAGTAT GGGCCATCGA CCAATATCGT 
GTGTGCCAGG AGGTGCTGGA ACGCTCCCGA GACGTGGTAG ATGATGTCAG CGTCTCTCTG 
CGCCTCTGGG ACACCTTTGG AGACCACCAC AAAGACCGTC GCTTTGCTTA TGGGAGATCT 
GATGTGGTGG TTCTGTGCTT CTCCATTGCC AACCCCAATT CCCTCCACCA TGTCAAGACC 
ATGTGGTACC CAGAAATCAA GCACTTCTGC CCCCGAGCAC CTGTCATCTT GGTGGGCTGC 
CAGTTGGACC TGCGCTACGC TGACCTGGAG GCTGTCAACA GGGCTAGGCG ACCCTTGGCT 
AGGCCCATCA AACCTAATGA AATCCTGCCC CCAGAGAAGG GTCGGGAGGT GGCCAAGGAG 
CTGGGCATCC CCTACTATGA GACCAGCGTG GTGGCCCAGT TCGGCATCAA GGACGTCTTT 
GACAACGCCA TCCGAGCTGC ACTCATCTCC CGCCGCCACC TGCAGTTCTG GAAGTCCCAC 
CTCCGCAATG TGCAGCGGCC TCTGCTGCAG GCACCCTTCC TACCCCCCAA GCCACCGCCC 
CCGATCATCG TGGTGCCCGA CCCTCCCTCC AGCAGCGAGG AGTGCCCCGC CCACCTCCTG 
GAGGACCCGC TCTGCGCGGA CGTCATCCTG GTGCTGCAGG AGCGGGTGCG CATCTTTGCC 
CACAAGATCT ACCTCTCCAC CTCTTCCTCC AAGTTCTATG ACCTGTTCCT CATGGACCTG 
AGTGAGGGGG AGCTGGGGGG CCCCTCGGAG CCAGGGGGCA CCCACCCAGA GGACCACCAG 
GGCCACTCTG ATCAACACCA CCACCATCAC CACCACCACC ATGGGCGAGA CTTCCTGCTC 
CGAGCAGCCA GCTTTGACGT GTGCGAGAGC GTGGATGAGG CTGGGGGCTC CGGTCCTGCT 
GGCCTCCGTG CTTCCACCAG CGACGGGATC TTACGGGGCA ACGGAACAGG GTACCTACCG 
GGCAGGGGTC GTGTGCTGTC TTCCTGGAGC CGAGCTTTTG TGAGCATCCA GGAAGAGATG 
GCAGAAGATC CTCTCACCTA CAAATCCCGG CTGATGGTGG TGGTGAAGAT GGACAGTTCC 
ATCCAGCCGG GGCCCTTCCG GGCTGTCCTC AAGTACCTGT ACACGGGGGA GCTAGATGAG 
AACGAGCGTG ACCTCATGCA CATTGCCCAC ATTGCTGAGC TGCTCGAGGT CTTTGATCTG 
CGCATGATGG TGGCCAACAT TCTCAACAAT GAGGCCTTCA TGAACCAGGA GATCACCAAG 
GCCTTCCACG TCCGCCGGAC CAACCGGGTT AAGGAGTGCT TGGCAAAAGG CACCTTCTCA 
GATGTGACCT TCATCCTGGA TGATGGCACC ATCAGCGCCC ACAAGCCCCT GTTGATTTCC 
AGCTGTGACT GGATGGCTGC CATGTTTGGG GGGCCATTTG TGGAGAGCTC CACCCGGGAG 
GTGGTGTTTC CCTACACAAG CAAGAGCTGC ATGCGGGCCG TGCTGGAATA CCTCTACACC 
GGCATGTTCA CCTCCAGCCC CGACCTGGAT GACATGAAGC TCATCATTCT AGCCAACCGC 
CTCTGCCTGC CACACCTGGT TGCCCTCACA GAGCAGTACA CAGTGACCGG GCTGATGGAA 
GCGACCCAGA TGATGGTGGA CATCGATGGG GACGTCCTTG TGTTCCTGGA ACTGGCTCAG 
TTCCACTGTG CGTACCAGCT GGCCGACTGG TGTCTCCACC ACATCTGCAC CAACTACAAC 
AACGTGTGCC GCAAGTTCCC CCGAGACATG AAGGCCATGT CCCCAGAAAA CCAGGAGTAT 
TTCGAGAAGC ATCGGTGGCC ACCTGTGTGG TACCTGAAGG AGGAAGATCA TTACCAGCGG 
GCACGGAAGG AGCGTGAGAA GGAGGACTAC CTCCACCTCA AGCGGCAGCC CAAACGGCGT 
TGGCTCTTCT GGAACAGTCC ATCCTCCCCG TCTTCCTCGG CAGCCTCCTC CTCATCCCCA 
TCTTCCTCCT CGGCTGTGGT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RHOBTB2 ( NM_001160037.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001153509.1 Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 2, mRNA.

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CloneID	OHu31989
Clone ID Related Accession (Same CDS sequence)	NM_001160037.1 , NM_001160037.2
Accession Version	NM_001160037.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2205bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-10
Organism	Homo sapiens(human)
Product	rho-related BTB domain-containing protein 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA289763.1, AB018260.2, AK292863.1, AA641575.1, AY009093.1 and BG255120.1. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN03465405, SAMN03465407 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAAGCGC GGTCCCGTTT AATGGATTCT GACATGGATT ATGAAAGGCC AAACGTAGAG 
ACCATCAAGT GCGTTGTGGT GGGGGACAAC GCCGTGGGTA AGACCAGGCT CATCTGTGCC 
CGCGCTTGCA ATGCCACCCT CACCCAGTAC CAGCTGCTGG CCACGCATGT GCCCACAGTA 
TGGGCCATCG ACCAATATCG TGTGTGCCAG GAGGTGCTGG AACGCTCCCG AGACGTGGTA 
GATGATGTCA GCGTCTCTCT GCGCCTCTGG GACACCTTTG GAGACCACCA CAAAGACCGT 
CGCTTTGCTT ATGGGAGATC TGATGTGGTG GTTCTGTGCT TCTCCATTGC CAACCCCAAT 
TCCCTCCACC ATGTCAAGAC CATGTGGTAC CCAGAAATCA AGCACTTCTG CCCCCGAGCA 
CCTGTCATCT TGGTGGGCTG CCAGTTGGAC CTGCGCTACG CTGACCTGGA GGCTGTCAAC 
AGGGCTAGGC GACCCTTGGC TAGGCCCATC AAACCTAATG AAATCCTGCC CCCAGAGAAG 
GGTCGGGAGG TGGCCAAGGA GCTGGGCATC CCCTACTATG AGACCAGCGT GGTGGCCCAG 
TTCGGCATCA AGGACGTCTT TGACAACGCC ATCCGAGCTG CACTCATCTC CCGCCGCCAC 
CTGCAGTTCT GGAAGTCCCA CCTCCGCAAT GTGCAGCGGC CTCTGCTGCA GGCACCCTTC 
CTACCCCCCA AGCCACCGCC CCCGATCATC GTGGTGCCCG ACCCTCCCTC CAGCAGCGAG 
GAGTGCCCCG CCCACCTCCT GGAGGACCCG CTCTGCGCGG ACGTCATCCT GGTGCTGCAG 
GAGCGGGTGC GCATCTTTGC CCACAAGATC TACCTCTCCA CCTCTTCCTC CAAGTTCTAT 
GACCTGTTCC TCATGGACCT GAGTGAGGGG GAGCTGGGGG GCCCCTCGGA GCCAGGGGGC 
ACCCACCCAG AGGACCACCA GGGCCACTCT GATCAACACC ACCACCATCA CCACCACCAC 
CATGGGCGAG ACTTCCTGCT CCGAGCAGCC AGCTTTGACG TGTGCGAGAG CGTGGATGAG 
GCTGGGGGCT CCGGTCCTGC TGGCCTCCGT GCTTCCACCA GCGACGGGAT CTTACGGGGC 
AACGGAACAG GGTACCTACC GGGCAGGGGT CGTGTGCTGT CTTCCTGGAG CCGAGCTTTT 
GTGAGCATCC AGGAAGAGAT GGCAGAAGAT CCTCTCACCT ACAAATCCCG GCTGATGGTG 
GTGGTGAAGA TGGACAGTTC CATCCAGCCG GGGCCCTTCC GGGCTGTCCT CAAGTACCTG 
TACACGGGGG AGCTAGATGA GAACGAGCGT GACCTCATGC ACATTGCCCA CATTGCTGAG 
CTGCTCGAGG TCTTTGATCT GCGCATGATG GTGGCCAACA TTCTCAACAA TGAGGCCTTC 
ATGAACCAGG AGATCACCAA GGCCTTCCAC GTCCGCCGGA CCAACCGGGT TAAGGAGTGC 
TTGGCAAAAG GCACCTTCTC AGATGTGACC TTCATCCTGG ATGATGGCAC CATCAGCGCC 
CACAAGCCCC TGTTGATTTC CAGCTGTGAC TGGATGGCTG CCATGTTTGG GGGGCCATTT 
GTGGAGAGCT CCACCCGGGA GGTGGTGTTT CCCTACACAA GCAAGAGCTG CATGCGGGCC 
GTGCTGGAAT ACCTCTACAC CGGCATGTTC ACCTCCAGCC CCGACCTGGA TGACATGAAG 
CTCATCATTC TAGCCAACCG CCTCTGCCTG CCACACCTGG TTGCCCTCAC AGAGCAGTAC 
ACAGTGACCG GGCTGATGGA AGCGACCCAG ATGATGGTGG ACATCGATGG GGACGTCCTT 
GTGTTCCTGG AACTGGCTCA GTTCCACTGT GCGTACCAGC TGGCCGACTG GTGTCTCCAC 
CACATCTGCA CCAACTACAA CAACGTGTGC CGCAAGTTCC CCCGAGACAT GAAGGCCATG 
TCCCCAGAAA ACCAGGAGTA TTTCGAGAAG CATCGGTGGC CACCTGTGTG GTACCTGAAG 
GAGGAAGATC ATTACCAGCG GGCACGGAAG GAGCGTGAGA AGGAGGACTA CCTCCACCTC 
AAGCGGCAGC CCAAACGGCG TTGGCTCTTC TGGAACAGTC CATCCTCCCC GTCTTCCTCG 
GCAGCCTCCT CCTCATCCCC ATCTTCCTCC TCGGCTGTGG TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001153509.1
CDS	25..2229
Translation	MKARSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSPSSSSAVV

Target ORF information:

RefSeq Version	NM_001160037.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001160037.1

ORF Insert Sequence:

ATGAAAGCGC GGTCCCGTTT AATGGATTCT GACATGGATT ATGAAAGGCC AAACGTAGAG 
ACCATCAAGT GCGTTGTGGT GGGGGACAAC GCCGTGGGTA AGACCAGGCT CATCTGTGCC 
CGCGCTTGCA ATGCCACCCT CACCCAGTAC CAGCTGCTGG CCACGCATGT GCCCACAGTA 
TGGGCCATCG ACCAATATCG TGTGTGCCAG GAGGTGCTGG AACGCTCCCG AGACGTGGTA 
GATGATGTCA GCGTCTCTCT GCGCCTCTGG GACACCTTTG GAGACCACCA CAAAGACCGT 
CGCTTTGCTT ATGGGAGATC TGATGTGGTG GTTCTGTGCT TCTCCATTGC CAACCCCAAT 
TCCCTCCACC ATGTCAAGAC CATGTGGTAC CCAGAAATCA AGCACTTCTG CCCCCGAGCA 
CCTGTCATCT TGGTGGGCTG CCAGTTGGAC CTGCGCTACG CTGACCTGGA GGCTGTCAAC 
AGGGCTAGGC GACCCTTGGC TAGGCCCATC AAACCTAATG AAATCCTGCC CCCAGAGAAG 
GGTCGGGAGG TGGCCAAGGA GCTGGGCATC CCCTACTATG AGACCAGCGT GGTGGCCCAG 
TTCGGCATCA AGGACGTCTT TGACAACGCC ATCCGAGCTG CACTCATCTC CCGCCGCCAC 
CTGCAGTTCT GGAAGTCCCA CCTCCGCAAT GTGCAGCGGC CTCTGCTGCA GGCACCCTTC 
CTACCCCCCA AGCCACCGCC CCCGATCATC GTGGTGCCCG ACCCTCCCTC CAGCAGCGAG 
GAGTGCCCCG CCCACCTCCT GGAGGACCCG CTCTGCGCGG ACGTCATCCT GGTGCTGCAG 
GAGCGGGTGC GCATCTTTGC CCACAAGATC TACCTCTCCA CCTCTTCCTC CAAGTTCTAT 
GACCTGTTCC TCATGGACCT GAGTGAGGGG GAGCTGGGGG GCCCCTCGGA GCCAGGGGGC 
ACCCACCCAG AGGACCACCA GGGCCACTCT GATCAACACC ACCACCATCA CCACCACCAC 
CATGGGCGAG ACTTCCTGCT CCGAGCAGCC AGCTTTGACG TGTGCGAGAG CGTGGATGAG 
GCTGGGGGCT CCGGTCCTGC TGGCCTCCGT GCTTCCACCA GCGACGGGAT CTTACGGGGC 
AACGGAACAG GGTACCTACC GGGCAGGGGT CGTGTGCTGT CTTCCTGGAG CCGAGCTTTT 
GTGAGCATCC AGGAAGAGAT GGCAGAAGAT CCTCTCACCT ACAAATCCCG GCTGATGGTG 
GTGGTGAAGA TGGACAGTTC CATCCAGCCG GGGCCCTTCC GGGCTGTCCT CAAGTACCTG 
TACACGGGGG AGCTAGATGA GAACGAGCGT GACCTCATGC ACATTGCCCA CATTGCTGAG 
CTGCTCGAGG TCTTTGATCT GCGCATGATG GTGGCCAACA TTCTCAACAA TGAGGCCTTC 
ATGAACCAGG AGATCACCAA GGCCTTCCAC GTCCGCCGGA CCAACCGGGT TAAGGAGTGC 
TTGGCAAAAG GCACCTTCTC AGATGTGACC TTCATCCTGG ATGATGGCAC CATCAGCGCC 
CACAAGCCCC TGTTGATTTC CAGCTGTGAC TGGATGGCTG CCATGTTTGG GGGGCCATTT 
GTGGAGAGCT CCACCCGGGA GGTGGTGTTT CCCTACACAA GCAAGAGCTG CATGCGGGCC 
GTGCTGGAAT ACCTCTACAC CGGCATGTTC ACCTCCAGCC CCGACCTGGA TGACATGAAG 
CTCATCATTC TAGCCAACCG CCTCTGCCTG CCACACCTGG TTGCCCTCAC AGAGCAGTAC 
ACAGTGACCG GGCTGATGGA AGCGACCCAG ATGATGGTGG ACATCGATGG GGACGTCCTT 
GTGTTCCTGG AACTGGCTCA GTTCCACTGT GCGTACCAGC TGGCCGACTG GTGTCTCCAC 
CACATCTGCA CCAACTACAA CAACGTGTGC CGCAAGTTCC CCCGAGACAT GAAGGCCATG 
TCCCCAGAAA ACCAGGAGTA TTTCGAGAAG CATCGGTGGC CACCTGTGTG GTACCTGAAG 
GAGGAAGATC ATTACCAGCG GGCACGGAAG GAGCGTGAGA AGGAGGACTA CCTCCACCTC 
AAGCGGCAGC CCAAACGGCG TTGGCTCTTC TGGAACAGTC CATCCTCCCC GTCTTCCTCG 
GCAGCCTCCT CCTCATCCCC ATCTTCCTCC TCGGCTGTGG TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RHOBTB2 ( NM_001374791.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001361720.1 Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 4, mRNA.

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CloneID	OHu31667
Clone ID Related Accession (Same CDS sequence)	NM_001374791.1 , NM_015178.2 , NM_015178.3
Accession Version	NM_001374791.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2184bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	rho-related BTB domain-containing protein 2 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC107959.8. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.207353.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END##

ATGGATTCTG ACATGGATTA TGAAAGGCCA AACGTAGAGA CCATCAAGTG CGTTGTGGTG 
GGGGACAACG CCGTGGGTAA GACCAGGCTC ATCTGTGCCC GCGCTTGCAA TGCCACCCTC 
ACCCAGTACC AGCTGCTGGC CACGCATGTG CCCACAGTAT GGGCCATCGA CCAATATCGT 
GTGTGCCAGG AGGTGCTGGA ACGCTCCCGA GACGTGGTAG ATGATGTCAG CGTCTCTCTG 
CGCCTCTGGG ACACCTTTGG AGACCACCAC AAAGACCGTC GCTTTGCTTA TGGGAGATCT 
GATGTGGTGG TTCTGTGCTT CTCCATTGCC AACCCCAATT CCCTCCACCA TGTCAAGACC 
ATGTGGTACC CAGAAATCAA GCACTTCTGC CCCCGAGCAC CTGTCATCTT GGTGGGCTGC 
CAGTTGGACC TGCGCTACGC TGACCTGGAG GCTGTCAACA GGGCTAGGCG ACCCTTGGCT 
AGGCCCATCA AACCTAATGA AATCCTGCCC CCAGAGAAGG GTCGGGAGGT GGCCAAGGAG 
CTGGGCATCC CCTACTATGA GACCAGCGTG GTGGCCCAGT TCGGCATCAA GGACGTCTTT 
GACAACGCCA TCCGAGCTGC ACTCATCTCC CGCCGCCACC TGCAGTTCTG GAAGTCCCAC 
CTCCGCAATG TGCAGCGGCC TCTGCTGCAG GCACCCTTCC TACCCCCCAA GCCACCGCCC 
CCGATCATCG TGGTGCCCGA CCCTCCCTCC AGCAGCGAGG AGTGCCCCGC CCACCTCCTG 
GAGGACCCGC TCTGCGCGGA CGTCATCCTG GTGCTGCAGG AGCGGGTGCG CATCTTTGCC 
CACAAGATCT ACCTCTCCAC CTCTTCCTCC AAGTTCTATG ACCTGTTCCT CATGGACCTG 
AGTGAGGGGG AGCTGGGGGG CCCCTCGGAG CCAGGGGGCA CCCACCCAGA GGACCACCAG 
GGCCACTCTG ATCAACACCA CCACCATCAC CACCACCACC ATGGGCGAGA CTTCCTGCTC 
CGAGCAGCCA GCTTTGACGT GTGCGAGAGC GTGGATGAGG CTGGGGGCTC CGGTCCTGCT 
GGCCTCCGTG CTTCCACCAG CGACGGGATC TTACGGGGCA ACGGAACAGG GTACCTACCG 
GGCAGGGGTC GTGTGCTGTC TTCCTGGAGC CGAGCTTTTG TGAGCATCCA GGAAGAGATG 
GCAGAAGATC CTCTCACCTA CAAATCCCGG CTGATGGTGG TGGTGAAGAT GGACAGTTCC 
ATCCAGCCGG GGCCCTTCCG GGCTGTCCTC AAGTACCTGT ACACGGGGGA GCTAGATGAG 
AACGAGCGTG ACCTCATGCA CATTGCCCAC ATTGCTGAGC TGCTCGAGGT CTTTGATCTG 
CGCATGATGG TGGCCAACAT TCTCAACAAT GAGGCCTTCA TGAACCAGGA GATCACCAAG 
GCCTTCCACG TCCGCCGGAC CAACCGGGTT AAGGAGTGCT TGGCAAAAGG CACCTTCTCA 
GATGTGACCT TCATCCTGGA TGATGGCACC ATCAGCGCCC ACAAGCCCCT GTTGATTTCC 
AGCTGTGACT GGATGGCTGC CATGTTTGGG GGGCCATTTG TGGAGAGCTC CACCCGGGAG 
GTGGTGTTTC CCTACACAAG CAAGAGCTGC ATGCGGGCCG TGCTGGAATA CCTCTACACC 
GGCATGTTCA CCTCCAGCCC CGACCTGGAT GACATGAAGC TCATCATTCT AGCCAACCGC 
CTCTGCCTGC CACACCTGGT TGCCCTCACA GAGCAGTACA CAGTGACCGG GCTGATGGAA 
GCGACCCAGA TGATGGTGGA CATCGATGGG GACGTCCTTG TGTTCCTGGA ACTGGCTCAG 
TTCCACTGTG CGTACCAGCT GGCCGACTGG TGTCTCCACC ACATCTGCAC CAACTACAAC 
AACGTGTGCC GCAAGTTCCC CCGAGACATG AAGGCCATGT CCCCAGAAAA CCAGGAGTAT 
TTCGAGAAGC ATCGGTGGCC ACCTGTGTGG TACCTGAAGG AGGAAGATCA TTACCAGCGG 
GCACGGAAGG AGCGTGAGAA GGAGGACTAC CTCCACCTCA AGCGGCAGCC CAAACGGCGT 
TGGCTCTTCT GGAACAGTCC ATCCTCCCCG TCTTCCTCGG CAGCCTCCTC CTCATCCCCA 
TCTTCCTCCT CGGCTGTGGT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001361720.1
CDS	329..2512
Translation	MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSPSSSSAVV

Target ORF information:

RefSeq Version	NM_001374791.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001374791.1

ORF Insert Sequence:

ATGGATTCTG ACATGGATTA TGAAAGGCCA AACGTAGAGA CCATCAAGTG CGTTGTGGTG 
GGGGACAACG CCGTGGGTAA GACCAGGCTC ATCTGTGCCC GCGCTTGCAA TGCCACCCTC 
ACCCAGTACC AGCTGCTGGC CACGCATGTG CCCACAGTAT GGGCCATCGA CCAATATCGT 
GTGTGCCAGG AGGTGCTGGA ACGCTCCCGA GACGTGGTAG ATGATGTCAG CGTCTCTCTG 
CGCCTCTGGG ACACCTTTGG AGACCACCAC AAAGACCGTC GCTTTGCTTA TGGGAGATCT 
GATGTGGTGG TTCTGTGCTT CTCCATTGCC AACCCCAATT CCCTCCACCA TGTCAAGACC 
ATGTGGTACC CAGAAATCAA GCACTTCTGC CCCCGAGCAC CTGTCATCTT GGTGGGCTGC 
CAGTTGGACC TGCGCTACGC TGACCTGGAG GCTGTCAACA GGGCTAGGCG ACCCTTGGCT 
AGGCCCATCA AACCTAATGA AATCCTGCCC CCAGAGAAGG GTCGGGAGGT GGCCAAGGAG 
CTGGGCATCC CCTACTATGA GACCAGCGTG GTGGCCCAGT TCGGCATCAA GGACGTCTTT 
GACAACGCCA TCCGAGCTGC ACTCATCTCC CGCCGCCACC TGCAGTTCTG GAAGTCCCAC 
CTCCGCAATG TGCAGCGGCC TCTGCTGCAG GCACCCTTCC TACCCCCCAA GCCACCGCCC 
CCGATCATCG TGGTGCCCGA CCCTCCCTCC AGCAGCGAGG AGTGCCCCGC CCACCTCCTG 
GAGGACCCGC TCTGCGCGGA CGTCATCCTG GTGCTGCAGG AGCGGGTGCG CATCTTTGCC 
CACAAGATCT ACCTCTCCAC CTCTTCCTCC AAGTTCTATG ACCTGTTCCT CATGGACCTG 
AGTGAGGGGG AGCTGGGGGG CCCCTCGGAG CCAGGGGGCA CCCACCCAGA GGACCACCAG 
GGCCACTCTG ATCAACACCA CCACCATCAC CACCACCACC ATGGGCGAGA CTTCCTGCTC 
CGAGCAGCCA GCTTTGACGT GTGCGAGAGC GTGGATGAGG CTGGGGGCTC CGGTCCTGCT 
GGCCTCCGTG CTTCCACCAG CGACGGGATC TTACGGGGCA ACGGAACAGG GTACCTACCG 
GGCAGGGGTC GTGTGCTGTC TTCCTGGAGC CGAGCTTTTG TGAGCATCCA GGAAGAGATG 
GCAGAAGATC CTCTCACCTA CAAATCCCGG CTGATGGTGG TGGTGAAGAT GGACAGTTCC 
ATCCAGCCGG GGCCCTTCCG GGCTGTCCTC AAGTACCTGT ACACGGGGGA GCTAGATGAG 
AACGAGCGTG ACCTCATGCA CATTGCCCAC ATTGCTGAGC TGCTCGAGGT CTTTGATCTG 
CGCATGATGG TGGCCAACAT TCTCAACAAT GAGGCCTTCA TGAACCAGGA GATCACCAAG 
GCCTTCCACG TCCGCCGGAC CAACCGGGTT AAGGAGTGCT TGGCAAAAGG CACCTTCTCA 
GATGTGACCT TCATCCTGGA TGATGGCACC ATCAGCGCCC ACAAGCCCCT GTTGATTTCC 
AGCTGTGACT GGATGGCTGC CATGTTTGGG GGGCCATTTG TGGAGAGCTC CACCCGGGAG 
GTGGTGTTTC CCTACACAAG CAAGAGCTGC ATGCGGGCCG TGCTGGAATA CCTCTACACC 
GGCATGTTCA CCTCCAGCCC CGACCTGGAT GACATGAAGC TCATCATTCT AGCCAACCGC 
CTCTGCCTGC CACACCTGGT TGCCCTCACA GAGCAGTACA CAGTGACCGG GCTGATGGAA 
GCGACCCAGA TGATGGTGGA CATCGATGGG GACGTCCTTG TGTTCCTGGA ACTGGCTCAG 
TTCCACTGTG CGTACCAGCT GGCCGACTGG TGTCTCCACC ACATCTGCAC CAACTACAAC 
AACGTGTGCC GCAAGTTCCC CCGAGACATG AAGGCCATGT CCCCAGAAAA CCAGGAGTAT 
TTCGAGAAGC ATCGGTGGCC ACCTGTGTGG TACCTGAAGG AGGAAGATCA TTACCAGCGG 
GCACGGAAGG AGCGTGAGAA GGAGGACTAC CTCCACCTCA AGCGGCAGCC CAAACGGCGT 
TGGCTCTTCT GGAACAGTCC ATCCTCCCCG TCTTCCTCGG CAGCCTCCTC CTCATCCCCA 
TCTTCCTCCT CGGCTGTGGT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RHOBTB2 ( NM_015178.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055993.2 Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 3, mRNA.

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CloneID	OHu31667
Clone ID Related Accession (Same CDS sequence)	NM_001374791.1 , NM_015178.2 , NM_015178.3
Accession Version	NM_015178.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2184bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	rho-related BTB domain-containing protein 2 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC107959.8. On Oct 16, 2019 this sequence version replaced NM_015178.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB018260.2, AY009093.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGATTCTG ACATGGATTA TGAAAGGCCA AACGTAGAGA CCATCAAGTG CGTTGTGGTG 
GGGGACAACG CCGTGGGTAA GACCAGGCTC ATCTGTGCCC GCGCTTGCAA TGCCACCCTC 
ACCCAGTACC AGCTGCTGGC CACGCATGTG CCCACAGTAT GGGCCATCGA CCAATATCGT 
GTGTGCCAGG AGGTGCTGGA ACGCTCCCGA GACGTGGTAG ATGATGTCAG CGTCTCTCTG 
CGCCTCTGGG ACACCTTTGG AGACCACCAC AAAGACCGTC GCTTTGCTTA TGGGAGATCT 
GATGTGGTGG TTCTGTGCTT CTCCATTGCC AACCCCAATT CCCTCCACCA TGTCAAGACC 
ATGTGGTACC CAGAAATCAA GCACTTCTGC CCCCGAGCAC CTGTCATCTT GGTGGGCTGC 
CAGTTGGACC TGCGCTACGC TGACCTGGAG GCTGTCAACA GGGCTAGGCG ACCCTTGGCT 
AGGCCCATCA AACCTAATGA AATCCTGCCC CCAGAGAAGG GTCGGGAGGT GGCCAAGGAG 
CTGGGCATCC CCTACTATGA GACCAGCGTG GTGGCCCAGT TCGGCATCAA GGACGTCTTT 
GACAACGCCA TCCGAGCTGC ACTCATCTCC CGCCGCCACC TGCAGTTCTG GAAGTCCCAC 
CTCCGCAATG TGCAGCGGCC TCTGCTGCAG GCACCCTTCC TACCCCCCAA GCCACCGCCC 
CCGATCATCG TGGTGCCCGA CCCTCCCTCC AGCAGCGAGG AGTGCCCCGC CCACCTCCTG 
GAGGACCCGC TCTGCGCGGA CGTCATCCTG GTGCTGCAGG AGCGGGTGCG CATCTTTGCC 
CACAAGATCT ACCTCTCCAC CTCTTCCTCC AAGTTCTATG ACCTGTTCCT CATGGACCTG 
AGTGAGGGGG AGCTGGGGGG CCCCTCGGAG CCAGGGGGCA CCCACCCAGA GGACCACCAG 
GGCCACTCTG ATCAACACCA CCACCATCAC CACCACCACC ATGGGCGAGA CTTCCTGCTC 
CGAGCAGCCA GCTTTGACGT GTGCGAGAGC GTGGATGAGG CTGGGGGCTC CGGTCCTGCT 
GGCCTCCGTG CTTCCACCAG CGACGGGATC TTACGGGGCA ACGGAACAGG GTACCTACCG 
GGCAGGGGTC GTGTGCTGTC TTCCTGGAGC CGAGCTTTTG TGAGCATCCA GGAAGAGATG 
GCAGAAGATC CTCTCACCTA CAAATCCCGG CTGATGGTGG TGGTGAAGAT GGACAGTTCC 
ATCCAGCCGG GGCCCTTCCG GGCTGTCCTC AAGTACCTGT ACACGGGGGA GCTAGATGAG 
AACGAGCGTG ACCTCATGCA CATTGCCCAC ATTGCTGAGC TGCTCGAGGT CTTTGATCTG 
CGCATGATGG TGGCCAACAT TCTCAACAAT GAGGCCTTCA TGAACCAGGA GATCACCAAG 
GCCTTCCACG TCCGCCGGAC CAACCGGGTT AAGGAGTGCT TGGCAAAAGG CACCTTCTCA 
GATGTGACCT TCATCCTGGA TGATGGCACC ATCAGCGCCC ACAAGCCCCT GTTGATTTCC 
AGCTGTGACT GGATGGCTGC CATGTTTGGG GGGCCATTTG TGGAGAGCTC CACCCGGGAG 
GTGGTGTTTC CCTACACAAG CAAGAGCTGC ATGCGGGCCG TGCTGGAATA CCTCTACACC 
GGCATGTTCA CCTCCAGCCC CGACCTGGAT GACATGAAGC TCATCATTCT AGCCAACCGC 
CTCTGCCTGC CACACCTGGT TGCCCTCACA GAGCAGTACA CAGTGACCGG GCTGATGGAA 
GCGACCCAGA TGATGGTGGA CATCGATGGG GACGTCCTTG TGTTCCTGGA ACTGGCTCAG 
TTCCACTGTG CGTACCAGCT GGCCGACTGG TGTCTCCACC ACATCTGCAC CAACTACAAC 
AACGTGTGCC GCAAGTTCCC CCGAGACATG AAGGCCATGT CCCCAGAAAA CCAGGAGTAT 
TTCGAGAAGC ATCGGTGGCC ACCTGTGTGG TACCTGAAGG AGGAAGATCA TTACCAGCGG 
GCACGGAAGG AGCGTGAGAA GGAGGACTAC CTCCACCTCA AGCGGCAGCC CAAACGGCGT 
TGGCTCTTCT GGAACAGTCC ATCCTCCCCG TCTTCCTCGG CAGCCTCCTC CTCATCCCCA 
TCTTCCTCCT CGGCTGTGGT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055993.2
CDS	569..2752
Translation	MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSPSSSSAVV

Target ORF information:

RefSeq Version	NM_015178.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015178.3

ORF Insert Sequence:

ATGGATTCTG ACATGGATTA TGAAAGGCCA AACGTAGAGA CCATCAAGTG CGTTGTGGTG 
GGGGACAACG CCGTGGGTAA GACCAGGCTC ATCTGTGCCC GCGCTTGCAA TGCCACCCTC 
ACCCAGTACC AGCTGCTGGC CACGCATGTG CCCACAGTAT GGGCCATCGA CCAATATCGT 
GTGTGCCAGG AGGTGCTGGA ACGCTCCCGA GACGTGGTAG ATGATGTCAG CGTCTCTCTG 
CGCCTCTGGG ACACCTTTGG AGACCACCAC AAAGACCGTC GCTTTGCTTA TGGGAGATCT 
GATGTGGTGG TTCTGTGCTT CTCCATTGCC AACCCCAATT CCCTCCACCA TGTCAAGACC 
ATGTGGTACC CAGAAATCAA GCACTTCTGC CCCCGAGCAC CTGTCATCTT GGTGGGCTGC 
CAGTTGGACC TGCGCTACGC TGACCTGGAG GCTGTCAACA GGGCTAGGCG ACCCTTGGCT 
AGGCCCATCA AACCTAATGA AATCCTGCCC CCAGAGAAGG GTCGGGAGGT GGCCAAGGAG 
CTGGGCATCC CCTACTATGA GACCAGCGTG GTGGCCCAGT TCGGCATCAA GGACGTCTTT 
GACAACGCCA TCCGAGCTGC ACTCATCTCC CGCCGCCACC TGCAGTTCTG GAAGTCCCAC 
CTCCGCAATG TGCAGCGGCC TCTGCTGCAG GCACCCTTCC TACCCCCCAA GCCACCGCCC 
CCGATCATCG TGGTGCCCGA CCCTCCCTCC AGCAGCGAGG AGTGCCCCGC CCACCTCCTG 
GAGGACCCGC TCTGCGCGGA CGTCATCCTG GTGCTGCAGG AGCGGGTGCG CATCTTTGCC 
CACAAGATCT ACCTCTCCAC CTCTTCCTCC AAGTTCTATG ACCTGTTCCT CATGGACCTG 
AGTGAGGGGG AGCTGGGGGG CCCCTCGGAG CCAGGGGGCA CCCACCCAGA GGACCACCAG 
GGCCACTCTG ATCAACACCA CCACCATCAC CACCACCACC ATGGGCGAGA CTTCCTGCTC 
CGAGCAGCCA GCTTTGACGT GTGCGAGAGC GTGGATGAGG CTGGGGGCTC CGGTCCTGCT 
GGCCTCCGTG CTTCCACCAG CGACGGGATC TTACGGGGCA ACGGAACAGG GTACCTACCG 
GGCAGGGGTC GTGTGCTGTC TTCCTGGAGC CGAGCTTTTG TGAGCATCCA GGAAGAGATG 
GCAGAAGATC CTCTCACCTA CAAATCCCGG CTGATGGTGG TGGTGAAGAT GGACAGTTCC 
ATCCAGCCGG GGCCCTTCCG GGCTGTCCTC AAGTACCTGT ACACGGGGGA GCTAGATGAG 
AACGAGCGTG ACCTCATGCA CATTGCCCAC ATTGCTGAGC TGCTCGAGGT CTTTGATCTG 
CGCATGATGG TGGCCAACAT TCTCAACAAT GAGGCCTTCA TGAACCAGGA GATCACCAAG 
GCCTTCCACG TCCGCCGGAC CAACCGGGTT AAGGAGTGCT TGGCAAAAGG CACCTTCTCA 
GATGTGACCT TCATCCTGGA TGATGGCACC ATCAGCGCCC ACAAGCCCCT GTTGATTTCC 
AGCTGTGACT GGATGGCTGC CATGTTTGGG GGGCCATTTG TGGAGAGCTC CACCCGGGAG 
GTGGTGTTTC CCTACACAAG CAAGAGCTGC ATGCGGGCCG TGCTGGAATA CCTCTACACC 
GGCATGTTCA CCTCCAGCCC CGACCTGGAT GACATGAAGC TCATCATTCT AGCCAACCGC 
CTCTGCCTGC CACACCTGGT TGCCCTCACA GAGCAGTACA CAGTGACCGG GCTGATGGAA 
GCGACCCAGA TGATGGTGGA CATCGATGGG GACGTCCTTG TGTTCCTGGA ACTGGCTCAG 
TTCCACTGTG CGTACCAGCT GGCCGACTGG TGTCTCCACC ACATCTGCAC CAACTACAAC 
AACGTGTGCC GCAAGTTCCC CCGAGACATG AAGGCCATGT CCCCAGAAAA CCAGGAGTAT 
TTCGAGAAGC ATCGGTGGCC ACCTGTGTGG TACCTGAAGG AGGAAGATCA TTACCAGCGG 
GCACGGAAGG AGCGTGAGAA GGAGGACTAC CTCCACCTCA AGCGGCAGCC CAAACGGCGT 
TGGCTCTTCT GGAACAGTCC ATCCTCCCCG TCTTCCTCGG CAGCCTCCTC CTCATCCCCA 
TCTTCCTCCT CGGCTGTGGT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RHOBTB2 ( NM_001160037.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001153509.1 Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 2, mRNA.

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CloneID	OHu31989
Clone ID Related Accession (Same CDS sequence)	NM_001160037.1 , NM_001160037.2
Accession Version	NM_001160037.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2205bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-15
Organism	Homo sapiens(human)
Product	rho-related BTB domain-containing protein 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC107959.8. On Oct 16, 2019 this sequence version replaced NM_001160037.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: complete on the 3' end.

ATGAAAGCGC GGTCCCGTTT AATGGATTCT GACATGGATT ATGAAAGGCC AAACGTAGAG 
ACCATCAAGT GCGTTGTGGT GGGGGACAAC GCCGTGGGTA AGACCAGGCT CATCTGTGCC 
CGCGCTTGCA ATGCCACCCT CACCCAGTAC CAGCTGCTGG CCACGCATGT GCCCACAGTA 
TGGGCCATCG ACCAATATCG TGTGTGCCAG GAGGTGCTGG AACGCTCCCG AGACGTGGTA 
GATGATGTCA GCGTCTCTCT GCGCCTCTGG GACACCTTTG GAGACCACCA CAAAGACCGT 
CGCTTTGCTT ATGGGAGATC TGATGTGGTG GTTCTGTGCT TCTCCATTGC CAACCCCAAT 
TCCCTCCACC ATGTCAAGAC CATGTGGTAC CCAGAAATCA AGCACTTCTG CCCCCGAGCA 
CCTGTCATCT TGGTGGGCTG CCAGTTGGAC CTGCGCTACG CTGACCTGGA GGCTGTCAAC 
AGGGCTAGGC GACCCTTGGC TAGGCCCATC AAACCTAATG AAATCCTGCC CCCAGAGAAG 
GGTCGGGAGG TGGCCAAGGA GCTGGGCATC CCCTACTATG AGACCAGCGT GGTGGCCCAG 
TTCGGCATCA AGGACGTCTT TGACAACGCC ATCCGAGCTG CACTCATCTC CCGCCGCCAC 
CTGCAGTTCT GGAAGTCCCA CCTCCGCAAT GTGCAGCGGC CTCTGCTGCA GGCACCCTTC 
CTACCCCCCA AGCCACCGCC CCCGATCATC GTGGTGCCCG ACCCTCCCTC CAGCAGCGAG 
GAGTGCCCCG CCCACCTCCT GGAGGACCCG CTCTGCGCGG ACGTCATCCT GGTGCTGCAG 
GAGCGGGTGC GCATCTTTGC CCACAAGATC TACCTCTCCA CCTCTTCCTC CAAGTTCTAT 
GACCTGTTCC TCATGGACCT GAGTGAGGGG GAGCTGGGGG GCCCCTCGGA GCCAGGGGGC 
ACCCACCCAG AGGACCACCA GGGCCACTCT GATCAACACC ACCACCATCA CCACCACCAC 
CATGGGCGAG ACTTCCTGCT CCGAGCAGCC AGCTTTGACG TGTGCGAGAG CGTGGATGAG 
GCTGGGGGCT CCGGTCCTGC TGGCCTCCGT GCTTCCACCA GCGACGGGAT CTTACGGGGC 
AACGGAACAG GGTACCTACC GGGCAGGGGT CGTGTGCTGT CTTCCTGGAG CCGAGCTTTT 
GTGAGCATCC AGGAAGAGAT GGCAGAAGAT CCTCTCACCT ACAAATCCCG GCTGATGGTG 
GTGGTGAAGA TGGACAGTTC CATCCAGCCG GGGCCCTTCC GGGCTGTCCT CAAGTACCTG 
TACACGGGGG AGCTAGATGA GAACGAGCGT GACCTCATGC ACATTGCCCA CATTGCTGAG 
CTGCTCGAGG TCTTTGATCT GCGCATGATG GTGGCCAACA TTCTCAACAA TGAGGCCTTC 
ATGAACCAGG AGATCACCAA GGCCTTCCAC GTCCGCCGGA CCAACCGGGT TAAGGAGTGC 
TTGGCAAAAG GCACCTTCTC AGATGTGACC TTCATCCTGG ATGATGGCAC CATCAGCGCC 
CACAAGCCCC TGTTGATTTC CAGCTGTGAC TGGATGGCTG CCATGTTTGG GGGGCCATTT 
GTGGAGAGCT CCACCCGGGA GGTGGTGTTT CCCTACACAA GCAAGAGCTG CATGCGGGCC 
GTGCTGGAAT ACCTCTACAC CGGCATGTTC ACCTCCAGCC CCGACCTGGA TGACATGAAG 
CTCATCATTC TAGCCAACCG CCTCTGCCTG CCACACCTGG TTGCCCTCAC AGAGCAGTAC 
ACAGTGACCG GGCTGATGGA AGCGACCCAG ATGATGGTGG ACATCGATGG GGACGTCCTT 
GTGTTCCTGG AACTGGCTCA GTTCCACTGT GCGTACCAGC TGGCCGACTG GTGTCTCCAC 
CACATCTGCA CCAACTACAA CAACGTGTGC CGCAAGTTCC CCCGAGACAT GAAGGCCATG 
TCCCCAGAAA ACCAGGAGTA TTTCGAGAAG CATCGGTGGC CACCTGTGTG GTACCTGAAG 
GAGGAAGATC ATTACCAGCG GGCACGGAAG GAGCGTGAGA AGGAGGACTA CCTCCACCTC 
AAGCGGCAGC CCAAACGGCG TTGGCTCTTC TGGAACAGTC CATCCTCCCC GTCTTCCTCG 
GCAGCCTCCT CCTCATCCCC ATCTTCCTCC TCGGCTGTGG TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001153509.1
CDS	32..2236
Translation	MKARSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSPSSSSAVV

Target ORF information:

RefSeq Version	NM_001160037.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho related BTB domain containing 2 (RHOBTB2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001160037.2

ORF Insert Sequence:

ATGAAAGCGC GGTCCCGTTT AATGGATTCT GACATGGATT ATGAAAGGCC AAACGTAGAG 
ACCATCAAGT GCGTTGTGGT GGGGGACAAC GCCGTGGGTA AGACCAGGCT CATCTGTGCC 
CGCGCTTGCA ATGCCACCCT CACCCAGTAC CAGCTGCTGG CCACGCATGT GCCCACAGTA 
TGGGCCATCG ACCAATATCG TGTGTGCCAG GAGGTGCTGG AACGCTCCCG AGACGTGGTA 
GATGATGTCA GCGTCTCTCT GCGCCTCTGG GACACCTTTG GAGACCACCA CAAAGACCGT 
CGCTTTGCTT ATGGGAGATC TGATGTGGTG GTTCTGTGCT TCTCCATTGC CAACCCCAAT 
TCCCTCCACC ATGTCAAGAC CATGTGGTAC CCAGAAATCA AGCACTTCTG CCCCCGAGCA 
CCTGTCATCT TGGTGGGCTG CCAGTTGGAC CTGCGCTACG CTGACCTGGA GGCTGTCAAC 
AGGGCTAGGC GACCCTTGGC TAGGCCCATC AAACCTAATG AAATCCTGCC CCCAGAGAAG 
GGTCGGGAGG TGGCCAAGGA GCTGGGCATC CCCTACTATG AGACCAGCGT GGTGGCCCAG 
TTCGGCATCA AGGACGTCTT TGACAACGCC ATCCGAGCTG CACTCATCTC CCGCCGCCAC 
CTGCAGTTCT GGAAGTCCCA CCTCCGCAAT GTGCAGCGGC CTCTGCTGCA GGCACCCTTC 
CTACCCCCCA AGCCACCGCC CCCGATCATC GTGGTGCCCG ACCCTCCCTC CAGCAGCGAG 
GAGTGCCCCG CCCACCTCCT GGAGGACCCG CTCTGCGCGG ACGTCATCCT GGTGCTGCAG 
GAGCGGGTGC GCATCTTTGC CCACAAGATC TACCTCTCCA CCTCTTCCTC CAAGTTCTAT 
GACCTGTTCC TCATGGACCT GAGTGAGGGG GAGCTGGGGG GCCCCTCGGA GCCAGGGGGC 
ACCCACCCAG AGGACCACCA GGGCCACTCT GATCAACACC ACCACCATCA CCACCACCAC 
CATGGGCGAG ACTTCCTGCT CCGAGCAGCC AGCTTTGACG TGTGCGAGAG CGTGGATGAG 
GCTGGGGGCT CCGGTCCTGC TGGCCTCCGT GCTTCCACCA GCGACGGGAT CTTACGGGGC 
AACGGAACAG GGTACCTACC GGGCAGGGGT CGTGTGCTGT CTTCCTGGAG CCGAGCTTTT 
GTGAGCATCC AGGAAGAGAT GGCAGAAGAT CCTCTCACCT ACAAATCCCG GCTGATGGTG 
GTGGTGAAGA TGGACAGTTC CATCCAGCCG GGGCCCTTCC GGGCTGTCCT CAAGTACCTG 
TACACGGGGG AGCTAGATGA GAACGAGCGT GACCTCATGC ACATTGCCCA CATTGCTGAG 
CTGCTCGAGG TCTTTGATCT GCGCATGATG GTGGCCAACA TTCTCAACAA TGAGGCCTTC 
ATGAACCAGG AGATCACCAA GGCCTTCCAC GTCCGCCGGA CCAACCGGGT TAAGGAGTGC 
TTGGCAAAAG GCACCTTCTC AGATGTGACC TTCATCCTGG ATGATGGCAC CATCAGCGCC 
CACAAGCCCC TGTTGATTTC CAGCTGTGAC TGGATGGCTG CCATGTTTGG GGGGCCATTT 
GTGGAGAGCT CCACCCGGGA GGTGGTGTTT CCCTACACAA GCAAGAGCTG CATGCGGGCC 
GTGCTGGAAT ACCTCTACAC CGGCATGTTC ACCTCCAGCC CCGACCTGGA TGACATGAAG 
CTCATCATTC TAGCCAACCG CCTCTGCCTG CCACACCTGG TTGCCCTCAC AGAGCAGTAC 
ACAGTGACCG GGCTGATGGA AGCGACCCAG ATGATGGTGG ACATCGATGG GGACGTCCTT 
GTGTTCCTGG AACTGGCTCA GTTCCACTGT GCGTACCAGC TGGCCGACTG GTGTCTCCAC 
CACATCTGCA CCAACTACAA CAACGTGTGC CGCAAGTTCC CCCGAGACAT GAAGGCCATG 
TCCCCAGAAA ACCAGGAGTA TTTCGAGAAG CATCGGTGGC CACCTGTGTG GTACCTGAAG 
GAGGAAGATC ATTACCAGCG GGCACGGAAG GAGCGTGAGA AGGAGGACTA CCTCCACCTC 
AAGCGGCAGC CCAAACGGCG TTGGCTCTTC TGGAACAGTC CATCCTCCCC GTCTTCCTCG 
GCAGCCTCCT CCTCATCCCC ATCTTCCTCC TCGGCTGTGG TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Missense Variants in RHOBTB2 Cause a Developmental and Epileptic Encephalopathy in Humans, and Altered Levels Cause Neurological Defects in Drosophila.
American journal of human genetics102(1)44-57(2018 Jan)
Straub J,Konrad EDH,Gr?ner J,Toutain A,Bok LA,Cho MT,Crawford HP,Dubbs H,Douglas G,Jobling R,Johnson D,Krock B,Mikati MA,Nesbitt A,Nicolai J,Phillips M,Poduri A,Ortiz-Gonzalez XR,Powis Z,Santani A,Smith L,Stegmann APA,Stumpel C,Vreeburg M,,Fliedner A,Gregor A,Sticht H,Zweier C

DBC2/RhoBTB2 functions as a tumor suppressor protein via Musashi-2 ubiquitination in breast cancer.
Oncogene36(20)2802-2812(2017 May)
Choi YM,Kim KB,Lee JH,Chun YK,An IS,An S,Bae S

Atypical Rho GTPases of the RhoBTB Subfamily: Roles in Vesicle Trafficking and Tumorigenesis.
Cells5(2)(2016 Jun)
Ji W,Rivero F

Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants.
PloS one10(10)e0141786(2015)
Prince TL,Kijima T,Tatokoro M,Lee S,Tsutsumi S,Yim K,Rivas C,Alarcon S,Schwartz H,Khamit-Kush K,Scroggins BT,Beebe K,Trepel JB,Neckers L

Hsp90-dependent assembly of the DBC2/RhoBTB2-Cullin3 E3-ligase complex.
PloS one9(3)e90054(2014)
Manjarrez JR,Sun L,Prince T,Matts RL

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RHOBTB2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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