RTF1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RTF1
Entrez Gene ID	23168
Full Name	RTF1 homolog, Paf1/RNA polymerase II complex component
Synonyms	GTL7,KIAA0252
General protein information	Preferred Names RTF1 homolog, Paf1/RNA polymerase II complex component Names RNA polymerase-associated protein RTF1 homolog Rtf1, Paf1/RNA polymerase II complex component, homolog ortholog of mouse gene trap locus 7
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q15.1
Summary	This locus may represent a gene involved in regulation of transcription elongation and chromatin remodeling, based on studies of similar proteins in other organisms. The encoded protein may bind single-stranded DNA. [provided by RefSeq, Sep 2010].
Disorder MIM:	611633

mRNA and Protein(s)

mRNA	Protein	Name
NM_015138.4	NP_055953.3	RNA polymerase-associated protein RTF1 homolog

Pathways from BioSystems

Homologies

Bos taurus (cattle)	RTF1	NP_001179414.1
Mus musculus (house mouse)	Rtf1	NP_084388.2
Drosophila melanogaster (fruit fly)	Rtf1	NP_611665.1
	RTF1	XP_001100507.1
Gallus gallus (chicken)	RTF1	XP_421139.3
Pan troglodytes (chimpanzee)	RTF1	XP_001142072.1
Canis lupus familiaris (dog)	RTF1	XP_544630.2
Danio rerio (zebrafish)	rtf1	NP_001077046.1
Xenopus tropicalis (tropical clawed frog)	rtf1	NP_001005068.1
Homo sapiens (human)	RTF1	NP_055953.3

Gene Ontology
Bibliography

Related articles in PubMed

Characterization of the Human Transcription Elongation Factor Rtf1: Evidence for Nonoverlapping Functions of Rtf1 and the Paf1 Complex.
Cao QF, Yamamoto J, Isobe T, Tateno S, Murase Y, Chen Y, Handa H, Yamaguchi Y
Molecular and cellular biology35(20)3459-70(2015 Oct)

Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.
Wier AD, Mayekar MK, H?roux A, Arndt KM, VanDemark AP
Proceedings of the National Academy of Sciences of the United States of America110(43)17290-5(2013 Oct)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

Hundreds of variants clustered in genomic loci and biological pathways affect human height.
Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Segr? AV, Speliotes EK, Wheeler E, Soranzo N, Park JH, Yang J, Gudbjartsson D, Heard-Costa NL, Randall JC, Qi L, Vernon Smith A, M?gi R, Pastinen T, Liang L, Heid IM, Luan J, Thorleifsson G, Winkler TW, Goddard ME, Sin Lo K, Palmer C, Workalemahu T, Aulchenko YS, Johansson A, Zillikens MC, Feitosa MF, Esko T, Johnson T, Ketkar S, Kraft P, Mangino M, Prokopenko I, Absher D, Albrecht E, Ernst F, Glazer NL, Hayward C, Hottenga JJ, Jacobs KB, Knowles JW, Kutalik Z, Monda KL, Polasek O, Preuss M, Rayner NW, Robertson NR, Steinthorsdottir V, Tyrer JP, Voight BF, Wiklund F, Xu J, Zhao JH, Nyholt DR, Pellikka N, Perola M, Perry JR, Surakka I, Tammesoo ML, Altmaier EL, Amin N, Aspelund T, Bhangale T, Boucher G, Chasman DI, Chen C, Coin L, Cooper MN, Dixon AL, Gibson Q, Grundberg E, Hao K, Juhani Junttila M, Kaplan LM, Kettunen J, K?nig IR, Kwan T, Lawrence RW, Levinson DF, Lorentzon M, McKnight B, Morris AP, M?ller M, Suh Ngwa J, Purcell S, Rafelt S, Salem RM, Salvi E, Sanna S, Shi J, Sovio U, Thompson JR, Turchin MC, Vandenput L, Verlaan DJ, Vitart V, White CC, Ziegler A, Almgren P, Balmforth AJ, Campbell H, Citterio L, De Grandi A, Dominiczak A, Duan J, Elliott P, Elosua R, Eriksson JG, Freimer NB, Geus EJ, Glorioso N, Haiqing S, Hartikainen AL, Havulinna AS, Hicks AA, Hui J, Igl W, Illig T, Jula A, Kajantie E, Kilpel?inen TO, Koiranen M, Kolcic I, Koskinen S, Kovacs P, Laitinen J, Liu J, Lokki ML, Marusic A, Maschio A, Meitinger T, Mulas A, Par? G, Parker AN, Peden JF, Petersmann A, Pichler I, Pietil?inen KH, Pouta A, Ridderstr?le M, Rotter JI, Sambrook JG, Sanders AR, Schmidt CO, Sinisalo J, Smit JH, Stringham HM, Bragi Walters G, Widen E, Wild SH, Willemsen G, Zagato L, Zgaga L, Zitting P, Alavere H, Farrall M, McArdle WL, Nelis M, Peters MJ, Ripatti S, van Meurs JB, Aben KK, Ardlie KG, Beckmann JS, Beilby JP, Bergman RN, Bergmann S, Collins FS, Cusi D, den Heijer M, Eiriksdottir G, Gejman PV, Hall AS, Hamsten A, Huikuri HV, Iribarren C, K?h?nen M, Kaprio J, Kathiresan S, Kiemeney L, Kocher T, Launer LJ, Lehtim?ki T, Melander O, Mosley TH Jr, Musk AW, Nieminen MS, O'Donnell CJ, Ohlsson C, Oostra B, Palmer LJ, Raitakari O, Ridker PM, Rioux JD, Rissanen A, Rivolta C, Schunkert H, Shuldiner AR, Siscovick DS, Stumvoll M, T?njes A, Tuomilehto J, van Ommen GJ, Viikari J, Heath AC, Martin NG, Montgomery GW, Province MA, Kayser M, Arnold AM, Atwood LD, Boerwinkle E, Chanock SJ, Deloukas P, Gieger C, Gr?nberg H, Hall P, Hattersley AT, Hengstenberg C, Hoffman W, Lathrop GM, Salomaa V, Schreiber S, Uda M, Waterworth D, Wright AF, Assimes TL, Barroso I, Hofman A, Mohlke KL, Boomsma DI, Caulfield MJ, Cupples LA, Erdmann J, Fox CS, Gudnason V, Gyllensten U, Harris TB, Hayes RB, Jarvelin MR, Mooser V, Munroe PB, Ouwehand WH, Penninx BW, Pramstaller PP, Quertermous T, Rudan I, Samani NJ, Spector TD, V?lzke H, Watkins H, Wilson JF, Groop LC, Haritunians T, Hu FB, Kaplan RC, Metspalu A, North KE, Schlessinger D, Wareham NJ, Hunter DJ, O'Connell JR, Strachan DP, Wichmann HE, Borecki IB, van Duijn CM, Schadt EE, Thorsteinsdottir U, Peltonen L, Uitterlinden AG, Visscher PM, Chatterjee N, Loos RJ, Boehnke M, McCarthy MI, Ingelsson E, Lindgren CM, Abecasis GR, Stefansson K, Frayling TM, Hirschhorn JN
Nature467(7317)832-8(2010 Oct)

The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS.
Kim J, Guermah M, Roeder RG
Cell140(4)491-503(2010 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Human Rtf1 as a transcription elongation factor.
Title: Characterization of the Human Transcription Elongation Factor Rtf1: Evidence for Nonoverlapping Functions of Rtf1 and the Paf1 Complex.

Data indicate that the Plus3 domain of the Rtf1 subunit mediates Paf1C recruitment to genes by binding a repeating domain within the phosphorylated elongation factor Spt5.
Title: Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following RTF1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RTF1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu21095	NM_015138.4 Latest version!	Homo sapiens RTF1 homolog, Paf1/RNA polymerase II complex component (RTF1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RTF1 ( NM_015138.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055953.3 Homo sapiens RTF1 homolog, Paf1/RNA polymerase II complex component (RTF1), mRNA.

Price & Availability↑

CloneID	OHu21095
Clone ID Related Accession (Same CDS sequence)	NM_015138.4
Accession Version	NM_015138.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2133bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	RNA polymerase-associated protein RTF1 homolog
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BF979715.1, D87440.2, AC087721.4 and CD367287.1. This sequence is a reference standard in the RefSeqGene project. On Aug 12, 2008 this sequence version replaced NM_015138.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D87440.2, BC015052.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCGCGGTC GCCTTTGTGT GGGTCGAGCA GCGGCGGCGG CGGCGGCAGT GGCGGTCCCA 
CTGGCAGGCG GGCAAGAGGG GAGTCCGGGC GGCGGCCGGC GTGGGAGCCG GGGGACCACC 
ATGGTAAAGA AGCGGAAAGG CCGCGTCGTG ATCGACTCGG ACACAGAGGA CAGCGGCAGC 
GACGAGAACC TGGATCAGGA GCTCTTGTCC CTGGCAAAGC GAAAGCGCAG TGACTCTGAG 
GAGAAGGAGC CGCCTGTGAG TCAGCCTGCA GCCTCGTCAG ACTCGGAGAC GTCTGACAGT 
GACGATGAGT GGACATTTGG GAGCAATAAA AATAAGAAGA AAGGAAAAGC CAGAAAAATA 
GAGAAGAAAG GAACCATGAA GAAACAGGCC AACAAAACTG CCTCCTCAGG CAGTTCAGAC 
AAAGACAGTT CAGCTGAGAG CTCAGCCCCT GAGGAAGGTG AAGTGTCAGA CTCTGACAGC 
AACAGCTCCT CTTCCAGTTC AGATTCAGAC TCTTCCTCAG AAGATGAAGA GTTCCATGAT 
GGCTATGGAG AAGACCTCAT GGGAGATGAG GAAGACAGGG CCCGTCTGGA ACAGATGACA 
GAGAAAGAGA GAGAGCAAGA ACTGTTCAAT CGCATAGAGA AGAGGGAGGT GTTGAAAAGA 
AGATTTGAAA TCAAGAAAAA ACTAAAAACA GCCAAAAAGA AAGAAAAGAA AGAAAAGAAG 
AAAAAGCAAG AAGAGGAGCA AGAAAAGAAA AAACTGACAC AGATTCAAGA ATCTCAGGTA 
ACATCCCACA ACAAGGAACG GCGTTCCAAG CGGGATGAGA AACTAGACAA GAAATCTCAA 
GCCATGGAGG AGCTAAAAGC AGAGCGAGAA AAACGAAAGA ACAGAACAGC TGAGCTCCTT 
GCCAAAAAAC AGCCATTAAA AACCAGTGAG GTCTACTCTG ATGATGAAGA GGAGGAAGAG 
GATGACAAAT CCAGTGAAAA GTCAGACCGC TCATCACGAA CATCATCGTC TGATGAAGAA 
GAGGAGAAAG AAGAGATCCC TCCCAAATCC CAACCAGTTT CCTTACCTGA AGAATTGAAT 
CGGGTTCGAT TATCACGGCA TAAGCTAGAA CGCTGGTGTC ACATGCCCTT CTTTGCTAAA 
ACTGTCACAG GATGTTTTGT GCGGATTGGC ATCGGAAACC ACAACAGCAA ACCAGTTTAC 
CGGGTCGCTG AGATTACGGG TGTTGTGGAA ACTGCCAAAG TTTACCAACT AGGTGGCACC 
AGAACAAACA AAGGGCTGCA ACTACGGCAT GGCAATGACC AACGCGTGTT CCGTTTAGAG 
TTTGTCTCAA ACCAAGAATT CACCGAAAGT GAGTTTATGA AGTGGAAAGA AGCGATGTTC 
TCTGCTGGCA TGCAGTTGCC CACTCTAGAT GAAATCAATA AAAAGGAATT ATCTATTAAA 
GAAGCTCTTA ATTATAAATT CAATGATCAG GACATTGAAG AGATTGTAAA AGAGAAAGAA 
AGGTTCAGAA AAGCTCCACC CAACTACGCT ATGAAGAAGA CTCAGCTACT GAAGGAAAAG 
GCCATGGCTG AGGACCTGGG GGATCAGGAC AAGGCCAAAC AAATCCAAGA TCAACTGAAT 
GAGCTGGAGG AACGGGCAGA GGCCCTGGAC CGCCAGCGGA CCAAGAACAT ATCCGCTATC 
AGTTACATCA ACCAGCGGAA CCGGGAGTGG AACATTGTAG AGTCTGAGAA GGCCCTTGTG 
GCTGAAAGTC ACAACATGAA AAACCAACAG ATGGATCCCT TTACTCGGCG GCAGTGCAAG 
CCTACCATCG TTTCTAATTC CAGAGACCCA GCTGTTCAAG CTGCCATCTT GGCCCAGCTG 
AATGCAAAAT ACGGTTCTGG AGTGTTACCA GATGCTCCAA AGGAAATGAG CAAGGGTCAA 
GGCAAAGATA AAGATTTGAA TTCTAAGTCA GCCAGTGACC TCTCAGAAGA TCTGTTCAAA 
GTACACGATT TTGATGTGAA GATTGACTTA CAAGTTCCCA GCTCAGAGTC AAAGGCTTTA 
GCCATCACCT CCAAGGCTCC GCCAGCCAAG GATGGGGCTC CAAGGAGATC TCTGAACTTG 
GAAGACTACA AAAAACGACG AGGGCTTATT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055953.3
CDS	13..2145
Translation	MRGRLCVGRAAAAAAAVAVPLAGGQEGSPGGGRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGNDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKELSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHNMKNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKEMSKGQGKDKDLNSKSASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI

Target ORF information:

RefSeq Version	NM_015138.4
Organism	Homo sapiens(human)
Definition	Homo sapiens RTF1 homolog, Paf1/RNA polymerase II complex component (RTF1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015138.4

ORF Insert Sequence:

ATGCGCGGTC GCCTTTGTGT GGGTCGAGCA GCGGCGGCGG CGGCGGCAGT GGCGGTCCCA 
CTGGCAGGCG GGCAAGAGGG GAGTCCGGGC GGCGGCCGGC GTGGGAGCCG GGGGACCACC 
ATGGTAAAGA AGCGGAAAGG CCGCGTCGTG ATCGACTCGG ACACAGAGGA CAGCGGCAGC 
GACGAGAACC TGGATCAGGA GCTCTTGTCC CTGGCAAAGC GAAAGCGCAG TGACTCTGAG 
GAGAAGGAGC CGCCTGTGAG TCAGCCTGCA GCCTCGTCAG ACTCGGAGAC GTCTGACAGT 
GACGATGAGT GGACATTTGG GAGCAATAAA AATAAGAAGA AAGGAAAAGC CAGAAAAATA 
GAGAAGAAAG GAACCATGAA GAAACAGGCC AACAAAACTG CCTCCTCAGG CAGTTCAGAC 
AAAGACAGTT CAGCTGAGAG CTCAGCCCCT GAGGAAGGTG AAGTGTCAGA CTCTGACAGC 
AACAGCTCCT CTTCCAGTTC AGATTCAGAC TCTTCCTCAG AAGATGAAGA GTTCCATGAT 
GGCTATGGAG AAGACCTCAT GGGAGATGAG GAAGACAGGG CCCGTCTGGA ACAGATGACA 
GAGAAAGAGA GAGAGCAAGA ACTGTTCAAT CGCATAGAGA AGAGGGAGGT GTTGAAAAGA 
AGATTTGAAA TCAAGAAAAA ACTAAAAACA GCCAAAAAGA AAGAAAAGAA AGAAAAGAAG 
AAAAAGCAAG AAGAGGAGCA AGAAAAGAAA AAACTGACAC AGATTCAAGA ATCTCAGGTA 
ACATCCCACA ACAAGGAACG GCGTTCCAAG CGGGATGAGA AACTAGACAA GAAATCTCAA 
GCCATGGAGG AGCTAAAAGC AGAGCGAGAA AAACGAAAGA ACAGAACAGC TGAGCTCCTT 
GCCAAAAAAC AGCCATTAAA AACCAGTGAG GTCTACTCTG ATGATGAAGA GGAGGAAGAG 
GATGACAAAT CCAGTGAAAA GTCAGACCGC TCATCACGAA CATCATCGTC TGATGAAGAA 
GAGGAGAAAG AAGAGATCCC TCCCAAATCC CAACCAGTTT CCTTACCTGA AGAATTGAAT 
CGGGTTCGAT TATCACGGCA TAAGCTAGAA CGCTGGTGTC ACATGCCCTT CTTTGCTAAA 
ACTGTCACAG GATGTTTTGT GCGGATTGGC ATCGGAAACC ACAACAGCAA ACCAGTTTAC 
CGGGTCGCTG AGATTACGGG TGTTGTGGAA ACTGCCAAAG TTTACCAACT AGGTGGCACC 
AGAACAAACA AAGGGCTGCA ACTACGGCAT GGCAATGACC AACGCGTGTT CCGTTTAGAG 
TTTGTCTCAA ACCAAGAATT CACCGAAAGT GAGTTTATGA AGTGGAAAGA AGCGATGTTC 
TCTGCTGGCA TGCAGTTGCC CACTCTAGAT GAAATCAATA AAAAGGAATT ATCTATTAAA 
GAAGCTCTTA ATTATAAATT CAATGATCAG GACATTGAAG AGATTGTAAA AGAGAAAGAA 
AGGTTCAGAA AAGCTCCACC CAACTACGCT ATGAAGAAGA CTCAGCTACT GAAGGAAAAG 
GCCATGGCTG AGGACCTGGG GGATCAGGAC AAGGCCAAAC AAATCCAAGA TCAACTGAAT 
GAGCTGGAGG AACGGGCAGA GGCCCTGGAC CGCCAGCGGA CCAAGAACAT ATCCGCTATC 
AGTTACATCA ACCAGCGGAA CCGGGAGTGG AACATTGTAG AGTCTGAGAA GGCCCTTGTG 
GCTGAAAGTC ACAACATGAA AAACCAACAG ATGGATCCCT TTACTCGGCG GCAGTGCAAG 
CCTACCATCG TTTCTAATTC CAGAGACCCA GCTGTTCAAG CTGCCATCTT GGCCCAGCTG 
AATGCAAAAT ACGGTTCTGG AGTGTTACCA GATGCTCCAA AGGAAATGAG CAAGGGTCAA 
GGCAAAGATA AAGATTTGAA TTCTAAGTCA GCCAGTGACC TCTCAGAAGA TCTGTTCAAA 
GTACACGATT TTGATGTGAA GATTGACTTA CAAGTTCCCA GCTCAGAGTC AAAGGCTTTA 
GCCATCACCT CCAAGGCTCC GCCAGCCAAG GATGGGGCTC CAAGGAGATC TCTGAACTTG 
GAAGACTACA AAAAACGACG AGGGCTTATT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Characterization of the Human Transcription Elongation Factor Rtf1: Evidence for Nonoverlapping Functions of Rtf1 and the Paf1 Complex.
Molecular and cellular biology35(20)3459-70(2015 Oct)
Cao QF,Yamamoto J,Isobe T,Tateno S,Murase Y,Chen Y,Handa H,Yamaguchi Y

Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.
Proceedings of the National Academy of Sciences of the United States of America110(43)17290-5(2013 Oct)
Wier AD,Mayekar MK,H?roux A,Arndt KM,VanDemark AP

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

Hundreds of variants clustered in genomic loci and biological pathways affect human height.
Nature467(7317)832-8(2010 Oct)
Lango Allen H,Estrada K,Lettre G,Berndt SI,Weedon MN,Rivadeneira F,Willer CJ,Jackson AU,Vedantam S,Raychaudhuri S,Ferreira T,Wood AR,Weyant RJ,Segr? AV,Speliotes EK,Wheeler E,Soranzo N,Park JH,Yang J,Gudbjartsson D,Heard-Costa NL,Randall JC,Qi L,Vernon Smith A,M?gi R,Pastinen T,Liang L,Heid IM,Luan J,Thorleifsson G,Winkler TW,Goddard ME,Sin Lo K,Palmer C,Workalemahu T,Aulchenko YS,Johansson A,Zillikens MC,Feitosa MF,Esko T,Johnson T,Ketkar S,Kraft P,Mangino M,Prokopenko I,Absher D,Albrecht E,Ernst F,Glazer NL,Hayward C,Hottenga JJ,Jacobs KB,Knowles JW,Kutalik Z,Monda KL,Polasek O,Preuss M,Rayner NW,Robertson NR,Steinthorsdottir V,Tyrer JP,Voight BF,Wiklund F,Xu J,Zhao JH,Nyholt DR,Pellikka N,Perola M,Perry JR,Surakka I,Tammesoo ML,Altmaier EL,Amin N,Aspelund T,Bhangale T,Boucher G,Chasman DI,Chen C,Coin L,Cooper MN,Dixon AL,Gibson Q,Grundberg E,Hao K,Juhani Junttila M,Kaplan LM,Kettunen J,K?nig IR,Kwan T,Lawrence RW,Levinson DF,Lorentzon M,McKnight B,Morris AP,M?ller M,Suh Ngwa J,Purcell S,Rafelt S,Salem RM,Salvi E,Sanna S,Shi J,Sovio U,Thompson JR,Turchin MC,Vandenput L,Verlaan DJ,Vitart V,White CC,Ziegler A,Almgren P,Balmforth AJ,Campbell H,Citterio L,De Grandi A,Dominiczak A,Duan J,Elliott P,Elosua R,Eriksson JG,Freimer NB,Geus EJ,Glorioso N,Haiqing S,Hartikainen AL,Havulinna AS,Hicks AA,Hui J,Igl W,Illig T,Jula A,Kajantie E,Kilpel?inen TO,Koiranen M,Kolcic I,Koskinen S,Kovacs P,Laitinen J,Liu J,Lokki ML,Marusic A,Maschio A,Meitinger T,Mulas A,Par? G,Parker AN,Peden JF,Petersmann A,Pichler I,Pietil?inen KH,Pouta A,Ridderstr?le M,Rotter JI,Sambrook JG,Sanders AR,Schmidt CO,Sinisalo J,Smit JH,Stringham HM,Bragi Walters G,Widen E,Wild SH,Willemsen G,Zagato L,Zgaga L,Zitting P,Alavere H,Farrall M,McArdle WL,Nelis M,Peters MJ,Ripatti S,van Meurs JB,Aben KK,Ardlie KG,Beckmann JS,Beilby JP,Bergman RN,Bergmann S,Collins FS,Cusi D,den Heijer M,Eiriksdottir G,Gejman PV,Hall AS,Hamsten A,Huikuri HV,Iribarren C,K?h?nen M,Kaprio J,Kathiresan S,Kiemeney L,Kocher T,Launer LJ,Lehtim?ki T,Melander O,Mosley TH Jr,Musk AW,Nieminen MS,O'Donnell CJ,Ohlsson C,Oostra B,Palmer LJ,Raitakari O,Ridker PM,Rioux JD,Rissanen A,Rivolta C,Schunkert H,Shuldiner AR,Siscovick DS,Stumvoll M,T?njes A,Tuomilehto J,van Ommen GJ,Viikari J,Heath AC,Martin NG,Montgomery GW,Province MA,Kayser M,Arnold AM,Atwood LD,Boerwinkle E,Chanock SJ,Deloukas P,Gieger C,Gr?nberg H,Hall P,Hattersley AT,Hengstenberg C,Hoffman W,Lathrop GM,Salomaa V,Schreiber S,Uda M,Waterworth D,Wright AF,Assimes TL,Barroso I,Hofman A,Mohlke KL,Boomsma DI,Caulfield MJ,Cupples LA,Erdmann J,Fox CS,Gudnason V,Gyllensten U,Harris TB,Hayes RB,Jarvelin MR,Mooser V,Munroe PB,Ouwehand WH,Penninx BW,Pramstaller PP,Quertermous T,Rudan I,Samani NJ,Spector TD,V?lzke H,Watkins H,Wilson JF,Groop LC,Haritunians T,Hu FB,Kaplan RC,Metspalu A,North KE,Schlessinger D,Wareham NJ,Hunter DJ,O'Connell JR,Strachan DP,Wichmann HE,Borecki IB,van Duijn CM,Schadt EE,Thorsteinsdottir U,Peltonen L,Uitterlinden AG,Visscher PM,Chatterjee N,Loos RJ,Boehnke M,McCarthy MI,Ingelsson E,Lindgren CM,Abecasis GR,Stefansson K,Frayling TM,Hirschhorn JN

The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS.
Cell140(4)491-503(2010 Feb)
Kim J,Guermah M,Roeder RG

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RTF1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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