gRNAs
The following DDN gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DDN cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu06815 | |
| Clone ID Related Accession (Same CDS sequence) | NM_015086.1 , NM_015086.2 | |
| Accession Version | NM_015086.1 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2136bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-10-01 | |
| Organism | Homo sapiens(human) | |
| Product | dendrin | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC039264.1 and AB018292.1. On Apr 1, 2005 this sequence version replaced XM_290598.3. ##Evidence-Data-START## Transcript exon combination :: AB018292.1, BC039264.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGCTGGATG GCCCACTGTT CTCCGAGGGG CCTGACAGCC CCCGGGAGCT CCAGGATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_055901.2 |
| CDS | 19..2154 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_015086.1 |
1 | ATGCTGGATG GCCCACTGTT CTCCGAGGGG CCTGACAGCC CCCGGGAGCT CCAGGATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu06815 | |
| Clone ID Related Accession (Same CDS sequence) | NM_015086.1 , NM_015086.2 | |
| Accession Version | NM_015086.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2136bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-07-05 | |
| Organism | Homo sapiens(human) | |
| Product | dendrin | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC011603.37, BC039264.1 and AB018292.1. On Nov 23, 2018 this sequence version replaced NM_015086.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC039264.1, AB018292.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000421952.3/ ENSP00000390590.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. | |
1 | ATGCTGGATG GCCCACTGTT CTCCGAGGGG CCTGACAGCC CCCGGGAGCT CCAGGATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_055901.2 |
| CDS | 89..2224 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_015086.2 |
1 | ATGCTGGATG GCCCACTGTT CTCCGAGGGG CCTGACAGCC CCCGGGAGCT CCAGGATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu65449 | |
| Clone ID Related Accession (Same CDS sequence) | XM_011538055.2 , XM_011538055.3 | |
| Accession Version | XM_011538055.2 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1974bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-06-05 | |
| Organism | Homo sapiens(human) | |
| Product | dendrin isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011538055.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGACTTCC AGGCCAGCCA CTGGGCTCGC GGGTTCCAGA ACCGCACGTG TGGGCCGCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_011536357.1 |
| CDS | 786..2759 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_011538055.2 |
1 | ATGGACTTCC AGGCCAGCCA CTGGGCTCGC GGGTTCCAGA ACCGCACGTG TGGGCCGCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu65449 | |
| Clone ID Related Accession (Same CDS sequence) | XM_011538055.2 , XM_011538055.3 | |
| Accession Version | XM_011538055.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1974bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-05 | |
| Organism | Homo sapiens(human) | |
| Product | dendrin isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011538055.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGACTTCC AGGCCAGCCA CTGGGCTCGC GGGTTCCAGA ACCGCACGTG TGGGCCGCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_011536357.1 |
| CDS | 787..2760 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_011538055.3 |
1 | ATGGACTTCC AGGCCAGCCA CTGGGCTCGC GGGTTCCAGA ACCGCACGTG TGGGCCGCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Translocation of dendrin to the podocyte nucleus in acute glomerular injury in patients with IgA nephropathy. |
Yes-associated protein (YAP) promotes cell survival by inhibiting proapoptotic dendrin signaling. |
Dendrin location in podocytes is associated with disease progression in animal and human glomerulopathy. |
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. |
