GGA2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GGA2
Entrez Gene ID	23062
Full Name	golgi associated, gamma adaptin ear containing, ARF binding protein 2
Synonyms	VEAR
General protein information	Preferred Names golgi associated, gamma adaptin ear containing, ARF binding protein 2 Names ADP-ribosylation factor-binding protein GGA2 VHS domain and ear domain of gamma-adaptin VHS domain and ear domain-containing protein gamma-adaptin-related protein 2 golgi-localized, gamma ear-containing, ARF-binding protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p12.2
Summary	This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly. [provided by RefSeq, Jul 2008].
Disorder MIM:	606005

mRNA and Protein(s)

mRNA	Protein	Name
NM_015044.4	NP_055859.1	ADP-ribosylation factor-binding protein GGA2
XM_017023074.1	XP_016878563.1	ADP-ribosylation factor-binding protein GGA2 isoform X1
XM_024450200.1	XP_024305968.1	ADP-ribosylation factor-binding protein GGA2 isoform X1
XM_017023075.1	XP_016878564.1	ADP-ribosylation factor-binding protein GGA2 isoform X2

Pathways from BioSystems

Homologies

	GGA2	XP_002802479.1
Bos taurus (cattle)	GGA2	XP_005224861.1
Homo sapiens (human)	GGA2	NP_055859.1
Pan troglodytes (chimpanzee)	GGA2	XP_001162100.3
Canis lupus familiaris (dog)	GGA2	XP_005621474.1
Gallus gallus (chicken)	GGA2	XP_004945327.1
Mus musculus (house mouse)	Gga2	NP_083034.1
Rattus norvegicus (Norway rat)	Gga2	NP_001093989.1

Gene Ontology
Bibliography

Related articles in PubMed

GGA2 interacts with EGFR cytoplasmic domain to stabilize the receptor expression and promote cell growth.
Uemura T, Kametaka S, Waguri S
Scientific reports8(1)1368(2018 Jan)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Conserved role for Gga proteins in phosphatidylinositol 4-kinase localization to the
Daboussi L, Costaguta G, Ghukasyan R, Payne GS
Proceedings of the National Academy of Sciences of the United States of America114(13)3433-3438(2017 Mar)

Regulation of ?
Zhang M, Huang W, Gao J, Terry AV, Wu G
Scientific reports637921(2016 Nov)

The Golgi-Localized ?-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-? Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1).
von Einem B, Wahler A, Schips T, Serrano-Pozo A, Proepper C, Boeckers TM, Rueck A, Wirth T, Hyman BT, Danzer KM, Thal DR, von Arnim CA
PloS one10(6)e0129047(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These data indicate that clathrin is required for the function of AP-1- and GGA-coated carriers at the trans-Golgi network but may be dispensable for outward traffic en route to the plasma membrane.
Title: Clathrin terminal domain-ligand interactions regulate sorting of mannose 6-phosphate receptors mediated by AP-1 and GGA adaptors.

GGA2 mediates a vital function that cannot be compensated for by GGA1and/or GGA3.
Title: Analysis of Gga null mice demonstrates a non-redundant role for mammalian GGA2 during development.

GGA overexpression causes various sorting defects as measured by recycling of CD-MPR, internalization of transferrin receptor, and the subcellular localization of proteins like Tsg101, ubiquitin, and Hrs.
Title: Defects in cellular sorting and retroviral assembly induced by GGA overexpression.

GGA2 is recruited to the trans-Golgi network independently of the other Golgi-localized, gamma-ear-containing, ARF-binding proteins and is required for the efficient sorting of lysosomal enzymes
Title: Specific depletion of GGA2 causes cathepsin D missorting in HeLa cells.

p56 tightly cooperates with the GGAs in the sorting of cathepsin D to lysosomes, probably by enabling the movement of GGA-containing transport carriers.
Title: The trans-Golgi network accessory protein p56 promotes long-range movement of GGA/clathrin-containing transport carriers and lysosomal enzyme sorting.

The following GGA2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GGA2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20372	NM_015044.4 Latest version!	Homo sapiens golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu65375	XM_024450200.1 Latest version!	Homo sapiens golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu65375	XM_017023074.1 Latest version!	Homo sapiens golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu85927	XM_017023075.1 Latest version!	Homo sapiens golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GGA2 ( NM_015044.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055859.1 Homo sapiens golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2), mRNA.

Price & Availability↑

CloneID	OHu20372
Clone ID Related Accession (Same CDS sequence)	NM_015044.4
Accession Version	NM_015044.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1842bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	ADP-ribosylation factor-binding protein GGA2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA439738.1, AF165531.1 and AC008915.11. On Feb 25, 2010 this sequence version replaced NM_015044.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.200435.1, SRR1660805.208236.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000309859.8/ ENSP00000311962.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGA CCGCGGTGGC GGCGGCTGTG GCGGGAACCG AGTCGGCCCA GGGTCCCCCG 
GGCCCGGCAG CGTCGCTGGA GCTGTGGCTC AACAAAGCCA CAGACCCAAG CATGTCGGAA 
CAGGATTGGT CAGCTATCCA GAATTTCTGT GAGCAGGTGA ACACTGACCC CAATGGCCCC 
ACACATGCGC CCTGGCTACT GGCCCACAAG ATCCAGTCTC CGCAAGAGAA GGAAGCTCTT 
TATGCCTTAA CGGTGCTGGA GATGTGCATG AACCACTGTG GGGAGAAGTT CCACAGCGAG 
GTGGCCAAAT TTCGTTTCCT GAACGAACTG ATCAAAGTGT TGTCCCCAAA GTACCTGGGG 
TCCTGGGCCA CAGGAAAAGT TAAAGGAAGA GTCATTGAAA TACTCTTCAG TTGGACAGTC 
TGGTTTCCGG AAGACATCAA GATTCGAGAC GCTTATCAGA TGCTGAAGAA ACAAGGAATT 
ATAAAACAAG ACCCTAAACT ACCAGTGGAT AAAATCTTAC CCCCACCATC TCCCTGGCCC 
AAGAGCTCCA TCTTTGATGC TGATGAAGAA AAGTCCAAGC TTCTGACAAG GCTTCTAAAG 
AGCAACCACC CCGAGGACCT TCAGGCTGCA AACCGGTTAA TCAAGAATTT GGTCAAGGAG 
GAACAAGAAA AATCGGAGAA GGTGTCCAAG AGGGTCAGTG CGGTGGAGGA AGTGCGAAGC 
CATGTGAAGG TGCTGCAGGA GATGCTGAGC ATGTACCGCA GGCCAGGGCA GGCCCCGCCC 
GACCAGGAGG CCCTGCAGGT CGTGTATGAG AGGTGTGAAA AGCTGCGGCC CACGCTGTTC 
CGGTTGGCGA GTGACACCAC TGATGACGAT GATGCACTCG CGGAAATTCT CCAGGCAAAT 
GACCTCCTCA CCCAAGGAGT TCTGCTGTAC AAACAGGTGA TGGAGGGCCG GGTCACCTTT 
GGAAACAGAG TGACCAGCTC ATTGGGAGAC ATCCCTGTCT CCAGAGTCTT TCAGAATCCA 
GCAGGCTGCA TGAAGACCTG CCCCCTGATT GACTTGGAGG TGGACAATGG ACCTGCGCAG 
ATGGGGACTG TGGTGCCATC TTTGCTTCAT CAGGACCTGG CAGCCTTGGG AATCAGTGAT 
GCTCCTGTTA CAGGCATGGT TTCTGGTCAG AATTGCTGTG AGGAAAAGAG GAATCCCTCC 
TCCAGCACGC TGCCAGGCGG TGGTGTTCAG AACCCTTCTG CAGACAGGAA TTTGCTGGAC 
CTCCTCTCAG CACAGCCAGC TCCGTGCCCT CTGAATTATG TTTCGCAGAA AAGTGTCCCC 
AAGGAAGTGC CACCAGGTAC TAAGTCCTCT CCAGGTTGGT CCTGGGAGGC TGGCCCGTTG 
GCTCCTTCCC CATCTTCACA GAATACACCT CTGGCTCAAG TGTTTGTCCC TTTGGAGTCT 
GTTAAGCCCA GCAGCCTGCC GCCTCTCATT GTGTATGACC GGAATGGATT CAGAATTCTG 
CTCCACTTCT CCCAGACGGG AGCCCCTGGG CACCCAGAGG TACAGGTGCT GCTCTTGACC 
ATGATGAGCA CGGCTCCCCA GCCTGTCTGG GATATCATGT TTCAAGTGGC TGTGCCAAAG 
TCAATGAGAG TGAAGCTGCA GCCGGCATCC AGCTCCAAGC TTCCTGCATT CAGTCCTTTG 
ATGCCTCCAG CTGTGATATC TCAGATGCTG CTGCTTGACA ATCCACACAA AGAACCTATC 
CGCTTACGGT ACAAGCTGAC ATTCAACCAA GGTGGACAGC CTTTCAGCGA AGTAGGAGAA 
GTGAAAGACT TCCCAGACCT GGCTGTCTTG GGCGCAGCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055859.1
CDS	84..1925
Translation	MAATAVAAAVAGTESAQGPPGPAASLELWLNKATDPSMSEQDWSAIQNFCEQVNTDPNGPTHAPWLLAHKIQSPQEKEALYALTVLEMCMNHCGEKFHSEVAKFRFLNELIKVLSPKYLGSWATGKVKGRVIEILFSWTVWFPEDIKIRDAYQMLKKQGIIKQDPKLPVDKILPPPSPWPKSSIFDADEEKSKLLTRLLKSNHPEDLQAANRLIKNLVKEEQEKSEKVSKRVSAVEEVRSHVKVLQEMLSMYRRPGQAPPDQEALQVVYERCEKLRPTLFRLASDTTDDDDALAEILQANDLLTQGVLLYKQVMEGRVTFGNRVTSSLGDIPVSRVFQNPAGCMKTCPLIDLEVDNGPAQMGTVVPSLLHQDLAALGISDAPVTGMVSGQNCCEEKRNPSSSTLPGGGVQNPSADRNLLDLLSAQPAPCPLNYVSQKSVPKEVPPGTKSSPGWSWEAGPLAPSPSSQNTPLAQVFVPLESVKPSSLPPLIVYDRNGFRILLHFSQTGAPGHPEVQVLLLTMMSTAPQPVWDIMFQVAVPKSMRVKLQPASSSKLPAFSPLMPPAVISQMLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFPDLAVLGAA

Target ORF information:

RefSeq Version	NM_015044.4
Organism	Homo sapiens(human)
Definition	Homo sapiens golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015044.4

ORF Insert Sequence:

ATGGCGGCGA CCGCGGTGGC GGCGGCTGTG GCGGGAACCG AGTCGGCCCA GGGTCCCCCG 
GGCCCGGCAG CGTCGCTGGA GCTGTGGCTC AACAAAGCCA CAGACCCAAG CATGTCGGAA 
CAGGATTGGT CAGCTATCCA GAATTTCTGT GAGCAGGTGA ACACTGACCC CAATGGCCCC 
ACACATGCGC CCTGGCTACT GGCCCACAAG ATCCAGTCTC CGCAAGAGAA GGAAGCTCTT 
TATGCCTTAA CGGTGCTGGA GATGTGCATG AACCACTGTG GGGAGAAGTT CCACAGCGAG 
GTGGCCAAAT TTCGTTTCCT GAACGAACTG ATCAAAGTGT TGTCCCCAAA GTACCTGGGG 
TCCTGGGCCA CAGGAAAAGT TAAAGGAAGA GTCATTGAAA TACTCTTCAG TTGGACAGTC 
TGGTTTCCGG AAGACATCAA GATTCGAGAC GCTTATCAGA TGCTGAAGAA ACAAGGAATT 
ATAAAACAAG ACCCTAAACT ACCAGTGGAT AAAATCTTAC CCCCACCATC TCCCTGGCCC 
AAGAGCTCCA TCTTTGATGC TGATGAAGAA AAGTCCAAGC TTCTGACAAG GCTTCTAAAG 
AGCAACCACC CCGAGGACCT TCAGGCTGCA AACCGGTTAA TCAAGAATTT GGTCAAGGAG 
GAACAAGAAA AATCGGAGAA GGTGTCCAAG AGGGTCAGTG CGGTGGAGGA AGTGCGAAGC 
CATGTGAAGG TGCTGCAGGA GATGCTGAGC ATGTACCGCA GGCCAGGGCA GGCCCCGCCC 
GACCAGGAGG CCCTGCAGGT CGTGTATGAG AGGTGTGAAA AGCTGCGGCC CACGCTGTTC 
CGGTTGGCGA GTGACACCAC TGATGACGAT GATGCACTCG CGGAAATTCT CCAGGCAAAT 
GACCTCCTCA CCCAAGGAGT TCTGCTGTAC AAACAGGTGA TGGAGGGCCG GGTCACCTTT 
GGAAACAGAG TGACCAGCTC ATTGGGAGAC ATCCCTGTCT CCAGAGTCTT TCAGAATCCA 
GCAGGCTGCA TGAAGACCTG CCCCCTGATT GACTTGGAGG TGGACAATGG ACCTGCGCAG 
ATGGGGACTG TGGTGCCATC TTTGCTTCAT CAGGACCTGG CAGCCTTGGG AATCAGTGAT 
GCTCCTGTTA CAGGCATGGT TTCTGGTCAG AATTGCTGTG AGGAAAAGAG GAATCCCTCC 
TCCAGCACGC TGCCAGGCGG TGGTGTTCAG AACCCTTCTG CAGACAGGAA TTTGCTGGAC 
CTCCTCTCAG CACAGCCAGC TCCGTGCCCT CTGAATTATG TTTCGCAGAA AAGTGTCCCC 
AAGGAAGTGC CACCAGGTAC TAAGTCCTCT CCAGGTTGGT CCTGGGAGGC TGGCCCGTTG 
GCTCCTTCCC CATCTTCACA GAATACACCT CTGGCTCAAG TGTTTGTCCC TTTGGAGTCT 
GTTAAGCCCA GCAGCCTGCC GCCTCTCATT GTGTATGACC GGAATGGATT CAGAATTCTG 
CTCCACTTCT CCCAGACGGG AGCCCCTGGG CACCCAGAGG TACAGGTGCT GCTCTTGACC 
ATGATGAGCA CGGCTCCCCA GCCTGTCTGG GATATCATGT TTCAAGTGGC TGTGCCAAAG 
TCAATGAGAG TGAAGCTGCA GCCGGCATCC AGCTCCAAGC TTCCTGCATT CAGTCCTTTG 
ATGCCTCCAG CTGTGATATC TCAGATGCTG CTGCTTGACA ATCCACACAA AGAACCTATC 
CGCTTACGGT ACAAGCTGAC ATTCAACCAA GGTGGACAGC CTTTCAGCGA AGTAGGAGAA 
GTGAAAGACT TCCCAGACCT GGCTGTCTTG GGCGCAGCCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GGA2 ( XM_017023074.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016878563.1 Homo sapiens golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu65375
Clone ID Related Accession (Same CDS sequence)	XM_017023074.1 , XM_024450200.1
Accession Version	XM_017023074.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1731bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	ADP-ribosylation factor-binding protein GGA2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGGAAC AGGATTGGTC AGCTATCCAG AATTTCTGTG AGCAGGTGAA CACTGACCCC 
AATGGCCCCA CACATGCGCC CTGGCTACTG GCCCACAAGA TCCAGTCTCC GCAAGAGAAG 
GAAGCTCTTT ATGCCTTAAC GGTGCTGGAG ATGTGCATGA ACCACTGTGG GGAGAAGTTC 
CACAGCGAGG TGGCCAAATT TCGTTTCCTG AACGAACTGA TCAAAGTGTT GTCCCCAAAG 
TACCTGGGGT CCTGGGCCAC AGGAAAAGTT AAAGGAAGAG TCATTGAAAT ACTCTTCAGT 
TGGACAGTCT GGTTTCCGGA AGACATCAAG ATTCGAGACG CTTATCAGAT GCTGAAGAAA 
CAAGGAATTA TAAAACAAGA CCCTAAACTA CCAGTGGATA AAATCTTACC CCCACCATCT 
CCCTGGCCCA AGAGCTCCAT CTTTGATGCT GATGAAGAAA AGTCCAAGCT TCTGACAAGG 
CTTCTAAAGA GCAACCACCC CGAGGACCTT CAGGCTGCAA ACCGGTTAAT CAAGAATTTG 
GTCAAGGAGG AACAAGAAAA ATCGGAGAAG GTGTCCAAGA GGGTCAGTGC GGTGGAGGAA 
GTGCGAAGCC ATGTGAAGGT GCTGCAGGAG ATGCTGAGCA TGTACCGCAG GCCAGGGCAG 
GCCCCGCCCG ACCAGGAGGC CCTGCAGGTC GTGTATGAGA GGTGTGAAAA GCTGCGGCCC 
ACGCTGTTCC GGTTGGCGAG TGACACCACT GATGACGATG ATGCACTCGC GGAAATTCTC 
CAGGCAAATG ACCTCCTCAC CCAAGGAGTT CTGCTGTACA AACAGGTGAT GGAGGGCCGG 
GTCACCTTTG GAAACAGAGT GACCAGCTCA TTGGGAGACA TCCCTGTCTC CAGAGTCTTT 
CAGAATCCAG CAGGCTGCAT GAAGACCTGC CCCCTGATTG ACTTGGAGGT GGACAATGGA 
CCTGCGCAGA TGGGGACTGT GGTGCCATCT TTGCTTCATC AGGACCTGGC AGCCTTGGGA 
ATCAGTGATG CTCCTGTTAC AGGCATGGTT TCTGGTCAGA ATTGCTGTGA GGAAAAGAGG 
AATCCCTCCT CCAGCACGCT GCCAGGCGGT GGTGTTCAGA ACCCTTCTGC AGACAGGAAT 
TTGCTGGACC TCCTCTCAGC ACAGCCAGCT CCGTGCCCTC TGAATTATGT TTCGCAGAAA 
AGTGTCCCCA AGGAAGTGCC ACCAGGTACT AAGTCCTCTC CAGGTTGGTC CTGGGAGGCT 
GGCCCGTTGG CTCCTTCCCC ATCTTCACAG AATACACCTC TGGCTCAAGT GTTTGTCCCT 
TTGGAGTCTG TTAAGCCCAG CAGCCTGCCG CCTCTCATTG TGTATGACCG GAATGGATTC 
AGAATTCTGC TCCACTTCTC CCAGACGGGA GCCCCTGGGC ACCCAGAGGT ACAGGTGCTG 
CTCTTGACCA TGATGAGCAC GGCTCCCCAG CCTGTCTGGG ATATCATGTT TCAAGTGGCT 
GTGCCAAAGT CAATGAGAGT GAAGCTGCAG CCGGCATCCA GCTCCAAGCT TCCTGCATTC 
AGTCCTTTGA TGCCTCCAGC TGTGATATCT CAGATGCTGC TGCTTGACAA TCCACACAAA 
GAACCTATCC GCTTACGGTA CAAGCTGACA TTCAACCAAG GTGGACAGCC TTTCAGCGAA 
GTAGGAGAAG TGAAAGACTT CCCAGACCTG GCTGTCTTGG GCGCAGCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016878563.1
CDS	3884..5614
Translation	MSEQDWSAIQNFCEQVNTDPNGPTHAPWLLAHKIQSPQEKEALYALTVLEMCMNHCGEKFHSEVAKFRFLNELIKVLSPKYLGSWATGKVKGRVIEILFSWTVWFPEDIKIRDAYQMLKKQGIIKQDPKLPVDKILPPPSPWPKSSIFDADEEKSKLLTRLLKSNHPEDLQAANRLIKNLVKEEQEKSEKVSKRVSAVEEVRSHVKVLQEMLSMYRRPGQAPPDQEALQVVYERCEKLRPTLFRLASDTTDDDDALAEILQANDLLTQGVLLYKQVMEGRVTFGNRVTSSLGDIPVSRVFQNPAGCMKTCPLIDLEVDNGPAQMGTVVPSLLHQDLAALGISDAPVTGMVSGQNCCEEKRNPSSSTLPGGGVQNPSADRNLLDLLSAQPAPCPLNYVSQKSVPKEVPPGTKSSPGWSWEAGPLAPSPSSQNTPLAQVFVPLESVKPSSLPPLIVYDRNGFRILLHFSQTGAPGHPEVQVLLLTMMSTAPQPVWDIMFQVAVPKSMRVKLQPASSSKLPAFSPLMPPAVISQMLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFPDLAVLGAA

Target ORF information:

RefSeq Version	XM_017023074.1
Organism	Homo sapiens(human)
Definition	Homo sapiens golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017023074.1

ORF Insert Sequence:

ATGTCGGAAC AGGATTGGTC AGCTATCCAG AATTTCTGTG AGCAGGTGAA CACTGACCCC 
AATGGCCCCA CACATGCGCC CTGGCTACTG GCCCACAAGA TCCAGTCTCC GCAAGAGAAG 
GAAGCTCTTT ATGCCTTAAC GGTGCTGGAG ATGTGCATGA ACCACTGTGG GGAGAAGTTC 
CACAGCGAGG TGGCCAAATT TCGTTTCCTG AACGAACTGA TCAAAGTGTT GTCCCCAAAG 
TACCTGGGGT CCTGGGCCAC AGGAAAAGTT AAAGGAAGAG TCATTGAAAT ACTCTTCAGT 
TGGACAGTCT GGTTTCCGGA AGACATCAAG ATTCGAGACG CTTATCAGAT GCTGAAGAAA 
CAAGGAATTA TAAAACAAGA CCCTAAACTA CCAGTGGATA AAATCTTACC CCCACCATCT 
CCCTGGCCCA AGAGCTCCAT CTTTGATGCT GATGAAGAAA AGTCCAAGCT TCTGACAAGG 
CTTCTAAAGA GCAACCACCC CGAGGACCTT CAGGCTGCAA ACCGGTTAAT CAAGAATTTG 
GTCAAGGAGG AACAAGAAAA ATCGGAGAAG GTGTCCAAGA GGGTCAGTGC GGTGGAGGAA 
GTGCGAAGCC ATGTGAAGGT GCTGCAGGAG ATGCTGAGCA TGTACCGCAG GCCAGGGCAG 
GCCCCGCCCG ACCAGGAGGC CCTGCAGGTC GTGTATGAGA GGTGTGAAAA GCTGCGGCCC 
ACGCTGTTCC GGTTGGCGAG TGACACCACT GATGACGATG ATGCACTCGC GGAAATTCTC 
CAGGCAAATG ACCTCCTCAC CCAAGGAGTT CTGCTGTACA AACAGGTGAT GGAGGGCCGG 
GTCACCTTTG GAAACAGAGT GACCAGCTCA TTGGGAGACA TCCCTGTCTC CAGAGTCTTT 
CAGAATCCAG CAGGCTGCAT GAAGACCTGC CCCCTGATTG ACTTGGAGGT GGACAATGGA 
CCTGCGCAGA TGGGGACTGT GGTGCCATCT TTGCTTCATC AGGACCTGGC AGCCTTGGGA 
ATCAGTGATG CTCCTGTTAC AGGCATGGTT TCTGGTCAGA ATTGCTGTGA GGAAAAGAGG 
AATCCCTCCT CCAGCACGCT GCCAGGCGGT GGTGTTCAGA ACCCTTCTGC AGACAGGAAT 
TTGCTGGACC TCCTCTCAGC ACAGCCAGCT CCGTGCCCTC TGAATTATGT TTCGCAGAAA 
AGTGTCCCCA AGGAAGTGCC ACCAGGTACT AAGTCCTCTC CAGGTTGGTC CTGGGAGGCT 
GGCCCGTTGG CTCCTTCCCC ATCTTCACAG AATACACCTC TGGCTCAAGT GTTTGTCCCT 
TTGGAGTCTG TTAAGCCCAG CAGCCTGCCG CCTCTCATTG TGTATGACCG GAATGGATTC 
AGAATTCTGC TCCACTTCTC CCAGACGGGA GCCCCTGGGC ACCCAGAGGT ACAGGTGCTG 
CTCTTGACCA TGATGAGCAC GGCTCCCCAG CCTGTCTGGG ATATCATGTT TCAAGTGGCT 
GTGCCAAAGT CAATGAGAGT GAAGCTGCAG CCGGCATCCA GCTCCAAGCT TCCTGCATTC 
AGTCCTTTGA TGCCTCCAGC TGTGATATCT CAGATGCTGC TGCTTGACAA TCCACACAAA 
GAACCTATCC GCTTACGGTA CAAGCTGACA TTCAACCAAG GTGGACAGCC TTTCAGCGAA 
GTAGGAGAAG TGAAAGACTT CCCAGACCTG GCTGTCTTGG GCGCAGCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GGA2 ( XM_024450200.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024305968.1 Homo sapiens golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu65375
Clone ID Related Accession (Same CDS sequence)	XM_017023074.1 , XM_024450200.1
Accession Version	XM_024450200.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1731bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ADP-ribosylation factor-binding protein GGA2 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGGAAC AGGATTGGTC AGCTATCCAG AATTTCTGTG AGCAGGTGAA CACTGACCCC 
AATGGCCCCA CACATGCGCC CTGGCTACTG GCCCACAAGA TCCAGTCTCC GCAAGAGAAG 
GAAGCTCTTT ATGCCTTAAC GGTGCTGGAG ATGTGCATGA ACCACTGTGG GGAGAAGTTC 
CACAGCGAGG TGGCCAAATT TCGTTTCCTG AACGAACTGA TCAAAGTGTT GTCCCCAAAG 
TACCTGGGGT CCTGGGCCAC AGGAAAAGTT AAAGGAAGAG TCATTGAAAT ACTCTTCAGT 
TGGACAGTCT GGTTTCCGGA AGACATCAAG ATTCGAGACG CTTATCAGAT GCTGAAGAAA 
CAAGGAATTA TAAAACAAGA CCCTAAACTA CCAGTGGATA AAATCTTACC CCCACCATCT 
CCCTGGCCCA AGAGCTCCAT CTTTGATGCT GATGAAGAAA AGTCCAAGCT TCTGACAAGG 
CTTCTAAAGA GCAACCACCC CGAGGACCTT CAGGCTGCAA ACCGGTTAAT CAAGAATTTG 
GTCAAGGAGG AACAAGAAAA ATCGGAGAAG GTGTCCAAGA GGGTCAGTGC GGTGGAGGAA 
GTGCGAAGCC ATGTGAAGGT GCTGCAGGAG ATGCTGAGCA TGTACCGCAG GCCAGGGCAG 
GCCCCGCCCG ACCAGGAGGC CCTGCAGGTC GTGTATGAGA GGTGTGAAAA GCTGCGGCCC 
ACGCTGTTCC GGTTGGCGAG TGACACCACT GATGACGATG ATGCACTCGC GGAAATTCTC 
CAGGCAAATG ACCTCCTCAC CCAAGGAGTT CTGCTGTACA AACAGGTGAT GGAGGGCCGG 
GTCACCTTTG GAAACAGAGT GACCAGCTCA TTGGGAGACA TCCCTGTCTC CAGAGTCTTT 
CAGAATCCAG CAGGCTGCAT GAAGACCTGC CCCCTGATTG ACTTGGAGGT GGACAATGGA 
CCTGCGCAGA TGGGGACTGT GGTGCCATCT TTGCTTCATC AGGACCTGGC AGCCTTGGGA 
ATCAGTGATG CTCCTGTTAC AGGCATGGTT TCTGGTCAGA ATTGCTGTGA GGAAAAGAGG 
AATCCCTCCT CCAGCACGCT GCCAGGCGGT GGTGTTCAGA ACCCTTCTGC AGACAGGAAT 
TTGCTGGACC TCCTCTCAGC ACAGCCAGCT CCGTGCCCTC TGAATTATGT TTCGCAGAAA 
AGTGTCCCCA AGGAAGTGCC ACCAGGTACT AAGTCCTCTC CAGGTTGGTC CTGGGAGGCT 
GGCCCGTTGG CTCCTTCCCC ATCTTCACAG AATACACCTC TGGCTCAAGT GTTTGTCCCT 
TTGGAGTCTG TTAAGCCCAG CAGCCTGCCG CCTCTCATTG TGTATGACCG GAATGGATTC 
AGAATTCTGC TCCACTTCTC CCAGACGGGA GCCCCTGGGC ACCCAGAGGT ACAGGTGCTG 
CTCTTGACCA TGATGAGCAC GGCTCCCCAG CCTGTCTGGG ATATCATGTT TCAAGTGGCT 
GTGCCAAAGT CAATGAGAGT GAAGCTGCAG CCGGCATCCA GCTCCAAGCT TCCTGCATTC 
AGTCCTTTGA TGCCTCCAGC TGTGATATCT CAGATGCTGC TGCTTGACAA TCCACACAAA 
GAACCTATCC GCTTACGGTA CAAGCTGACA TTCAACCAAG GTGGACAGCC TTTCAGCGAA 
GTAGGAGAAG TGAAAGACTT CCCAGACCTG GCTGTCTTGG GCGCAGCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024305968.1
CDS	422..2152
Translation	MSEQDWSAIQNFCEQVNTDPNGPTHAPWLLAHKIQSPQEKEALYALTVLEMCMNHCGEKFHSEVAKFRFLNELIKVLSPKYLGSWATGKVKGRVIEILFSWTVWFPEDIKIRDAYQMLKKQGIIKQDPKLPVDKILPPPSPWPKSSIFDADEEKSKLLTRLLKSNHPEDLQAANRLIKNLVKEEQEKSEKVSKRVSAVEEVRSHVKVLQEMLSMYRRPGQAPPDQEALQVVYERCEKLRPTLFRLASDTTDDDDALAEILQANDLLTQGVLLYKQVMEGRVTFGNRVTSSLGDIPVSRVFQNPAGCMKTCPLIDLEVDNGPAQMGTVVPSLLHQDLAALGISDAPVTGMVSGQNCCEEKRNPSSSTLPGGGVQNPSADRNLLDLLSAQPAPCPLNYVSQKSVPKEVPPGTKSSPGWSWEAGPLAPSPSSQNTPLAQVFVPLESVKPSSLPPLIVYDRNGFRILLHFSQTGAPGHPEVQVLLLTMMSTAPQPVWDIMFQVAVPKSMRVKLQPASSSKLPAFSPLMPPAVISQMLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFPDLAVLGAA

Target ORF information:

RefSeq Version	XM_024450200.1
Organism	Homo sapiens(human)
Definition	Homo sapiens golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024450200.1

ORF Insert Sequence:

ATGTCGGAAC AGGATTGGTC AGCTATCCAG AATTTCTGTG AGCAGGTGAA CACTGACCCC 
AATGGCCCCA CACATGCGCC CTGGCTACTG GCCCACAAGA TCCAGTCTCC GCAAGAGAAG 
GAAGCTCTTT ATGCCTTAAC GGTGCTGGAG ATGTGCATGA ACCACTGTGG GGAGAAGTTC 
CACAGCGAGG TGGCCAAATT TCGTTTCCTG AACGAACTGA TCAAAGTGTT GTCCCCAAAG 
TACCTGGGGT CCTGGGCCAC AGGAAAAGTT AAAGGAAGAG TCATTGAAAT ACTCTTCAGT 
TGGACAGTCT GGTTTCCGGA AGACATCAAG ATTCGAGACG CTTATCAGAT GCTGAAGAAA 
CAAGGAATTA TAAAACAAGA CCCTAAACTA CCAGTGGATA AAATCTTACC CCCACCATCT 
CCCTGGCCCA AGAGCTCCAT CTTTGATGCT GATGAAGAAA AGTCCAAGCT TCTGACAAGG 
CTTCTAAAGA GCAACCACCC CGAGGACCTT CAGGCTGCAA ACCGGTTAAT CAAGAATTTG 
GTCAAGGAGG AACAAGAAAA ATCGGAGAAG GTGTCCAAGA GGGTCAGTGC GGTGGAGGAA 
GTGCGAAGCC ATGTGAAGGT GCTGCAGGAG ATGCTGAGCA TGTACCGCAG GCCAGGGCAG 
GCCCCGCCCG ACCAGGAGGC CCTGCAGGTC GTGTATGAGA GGTGTGAAAA GCTGCGGCCC 
ACGCTGTTCC GGTTGGCGAG TGACACCACT GATGACGATG ATGCACTCGC GGAAATTCTC 
CAGGCAAATG ACCTCCTCAC CCAAGGAGTT CTGCTGTACA AACAGGTGAT GGAGGGCCGG 
GTCACCTTTG GAAACAGAGT GACCAGCTCA TTGGGAGACA TCCCTGTCTC CAGAGTCTTT 
CAGAATCCAG CAGGCTGCAT GAAGACCTGC CCCCTGATTG ACTTGGAGGT GGACAATGGA 
CCTGCGCAGA TGGGGACTGT GGTGCCATCT TTGCTTCATC AGGACCTGGC AGCCTTGGGA 
ATCAGTGATG CTCCTGTTAC AGGCATGGTT TCTGGTCAGA ATTGCTGTGA GGAAAAGAGG 
AATCCCTCCT CCAGCACGCT GCCAGGCGGT GGTGTTCAGA ACCCTTCTGC AGACAGGAAT 
TTGCTGGACC TCCTCTCAGC ACAGCCAGCT CCGTGCCCTC TGAATTATGT TTCGCAGAAA 
AGTGTCCCCA AGGAAGTGCC ACCAGGTACT AAGTCCTCTC CAGGTTGGTC CTGGGAGGCT 
GGCCCGTTGG CTCCTTCCCC ATCTTCACAG AATACACCTC TGGCTCAAGT GTTTGTCCCT 
TTGGAGTCTG TTAAGCCCAG CAGCCTGCCG CCTCTCATTG TGTATGACCG GAATGGATTC 
AGAATTCTGC TCCACTTCTC CCAGACGGGA GCCCCTGGGC ACCCAGAGGT ACAGGTGCTG 
CTCTTGACCA TGATGAGCAC GGCTCCCCAG CCTGTCTGGG ATATCATGTT TCAAGTGGCT 
GTGCCAAAGT CAATGAGAGT GAAGCTGCAG CCGGCATCCA GCTCCAAGCT TCCTGCATTC 
AGTCCTTTGA TGCCTCCAGC TGTGATATCT CAGATGCTGC TGCTTGACAA TCCACACAAA 
GAACCTATCC GCTTACGGTA CAAGCTGACA TTCAACCAAG GTGGACAGCC TTTCAGCGAA 
GTAGGAGAAG TGAAAGACTT CCCAGACCTG GCTGTCTTGG GCGCAGCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GGA2 ( XM_017023075.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016878564.1 Homo sapiens golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2), transcript variant X2, mRNA.

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CloneID	OHu85927
Clone ID Related Accession (Same CDS sequence)	XM_017023075.1
Accession Version	XM_017023075.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1581bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ADP-ribosylation factor-binding protein GGA2 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGCATGA ACCACTGTGG GGAGAAGTTC CACAGCGAGG TGGCCAAATT TCGTTTCCTG 
AACGAACTGA TCAAAGTGTT GTCCCCAAAG TACCTGGGGT CCTGGGCCAC AGGAAAAGTT 
AAAGGAAGAG TCATTGAAAT ACTCTTCAGT TGGACAGTCT GGTTTCCGGA AGACATCAAG 
ATTCGAGACG CTTATCAGAT GCTGAAGAAA CAAGGAATTA TAAAACAAGA CCCTAAACTA 
CCAGTGGATA AAATCTTACC CCCACCATCT CCCTGGCCCA AGAGCTCCAT CTTTGATGCT 
GATGAAGAAA AGTCCAAGCT TCTGACAAGG CTTCTAAAGA GCAACCACCC CGAGGACCTT 
CAGGCTGCAA ACCGGTTAAT CAAGAATTTG GTCAAGGAGG AACAAGAAAA ATCGGAGAAG 
GTGTCCAAGA GGGTCAGTGC GGTGGAGGAA GTGCGAAGCC ATGTGAAGGT GCTGCAGGAG 
ATGCTGAGCA TGTACCGCAG GCCAGGGCAG GCCCCGCCCG ACCAGGAGGC CCTGCAGGTC 
GTGTATGAGA GGTGTGAAAA GCTGCGGCCC ACGCTGTTCC GGTTGGCGAG TGACACCACT 
GATGACGATG ATGCACTCGC GGAAATTCTC CAGGCAAATG ACCTCCTCAC CCAAGGAGTT 
CTGCTGTACA AACAGGTGAT GGAGGGCCGG GTCACCTTTG GAAACAGAGT GACCAGCTCA 
TTGGGAGACA TCCCTGTCTC CAGAGTCTTT CAGAATCCAG CAGGCTGCAT GAAGACCTGC 
CCCCTGATTG ACTTGGAGGT GGACAATGGA CCTGCGCAGA TGGGGACTGT GGTGCCATCT 
TTGCTTCATC AGGACCTGGC AGCCTTGGGA ATCAGTGATG CTCCTGTTAC AGGCATGGTT 
TCTGGTCAGA ATTGCTGTGA GGAAAAGAGG AATCCCTCCT CCAGCACGCT GCCAGGCGGT 
GGTGTTCAGA ACCCTTCTGC AGACAGGAAT TTGCTGGACC TCCTCTCAGC ACAGCCAGCT 
CCGTGCCCTC TGAATTATGT TTCGCAGAAA AGTGTCCCCA AGGAAGTGCC ACCAGGTACT 
AAGTCCTCTC CAGGTTGGTC CTGGGAGGCT GGCCCGTTGG CTCCTTCCCC ATCTTCACAG 
AATACACCTC TGGCTCAAGT GTTTGTCCCT TTGGAGTCTG TTAAGCCCAG CAGCCTGCCG 
CCTCTCATTG TGTATGACCG GAATGGATTC AGAATTCTGC TCCACTTCTC CCAGACGGGA 
GCCCCTGGGC ACCCAGAGGT ACAGGTGCTG CTCTTGACCA TGATGAGCAC GGCTCCCCAG 
CCTGTCTGGG ATATCATGTT TCAAGTGGCT GTGCCAAAGT CAATGAGAGT GAAGCTGCAG 
CCGGCATCCA GCTCCAAGCT TCCTGCATTC AGTCCTTTGA TGCCTCCAGC TGTGATATCT 
CAGATGCTGC TGCTTGACAA TCCACACAAA GAACCTATCC GCTTACGGTA CAAGCTGACA 
TTCAACCAAG GTGGACAGCC TTTCAGCGAA GTAGGAGAAG TGAAAGACTT CCCAGACCTG 
GCTGTCTTGG GCGCAGCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016878564.1
CDS	348..1928
Translation	MCMNHCGEKFHSEVAKFRFLNELIKVLSPKYLGSWATGKVKGRVIEILFSWTVWFPEDIKIRDAYQMLKKQGIIKQDPKLPVDKILPPPSPWPKSSIFDADEEKSKLLTRLLKSNHPEDLQAANRLIKNLVKEEQEKSEKVSKRVSAVEEVRSHVKVLQEMLSMYRRPGQAPPDQEALQVVYERCEKLRPTLFRLASDTTDDDDALAEILQANDLLTQGVLLYKQVMEGRVTFGNRVTSSLGDIPVSRVFQNPAGCMKTCPLIDLEVDNGPAQMGTVVPSLLHQDLAALGISDAPVTGMVSGQNCCEEKRNPSSSTLPGGGVQNPSADRNLLDLLSAQPAPCPLNYVSQKSVPKEVPPGTKSSPGWSWEAGPLAPSPSSQNTPLAQVFVPLESVKPSSLPPLIVYDRNGFRILLHFSQTGAPGHPEVQVLLLTMMSTAPQPVWDIMFQVAVPKSMRVKLQPASSSKLPAFSPLMPPAVISQMLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFPDLAVLGAA

Target ORF information:

RefSeq Version	XM_017023075.1
Organism	Homo sapiens(human)
Definition	Homo sapiens golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017023075.1

ORF Insert Sequence:

ATGTGCATGA ACCACTGTGG GGAGAAGTTC CACAGCGAGG TGGCCAAATT TCGTTTCCTG 
AACGAACTGA TCAAAGTGTT GTCCCCAAAG TACCTGGGGT CCTGGGCCAC AGGAAAAGTT 
AAAGGAAGAG TCATTGAAAT ACTCTTCAGT TGGACAGTCT GGTTTCCGGA AGACATCAAG 
ATTCGAGACG CTTATCAGAT GCTGAAGAAA CAAGGAATTA TAAAACAAGA CCCTAAACTA 
CCAGTGGATA AAATCTTACC CCCACCATCT CCCTGGCCCA AGAGCTCCAT CTTTGATGCT 
GATGAAGAAA AGTCCAAGCT TCTGACAAGG CTTCTAAAGA GCAACCACCC CGAGGACCTT 
CAGGCTGCAA ACCGGTTAAT CAAGAATTTG GTCAAGGAGG AACAAGAAAA ATCGGAGAAG 
GTGTCCAAGA GGGTCAGTGC GGTGGAGGAA GTGCGAAGCC ATGTGAAGGT GCTGCAGGAG 
ATGCTGAGCA TGTACCGCAG GCCAGGGCAG GCCCCGCCCG ACCAGGAGGC CCTGCAGGTC 
GTGTATGAGA GGTGTGAAAA GCTGCGGCCC ACGCTGTTCC GGTTGGCGAG TGACACCACT 
GATGACGATG ATGCACTCGC GGAAATTCTC CAGGCAAATG ACCTCCTCAC CCAAGGAGTT 
CTGCTGTACA AACAGGTGAT GGAGGGCCGG GTCACCTTTG GAAACAGAGT GACCAGCTCA 
TTGGGAGACA TCCCTGTCTC CAGAGTCTTT CAGAATCCAG CAGGCTGCAT GAAGACCTGC 
CCCCTGATTG ACTTGGAGGT GGACAATGGA CCTGCGCAGA TGGGGACTGT GGTGCCATCT 
TTGCTTCATC AGGACCTGGC AGCCTTGGGA ATCAGTGATG CTCCTGTTAC AGGCATGGTT 
TCTGGTCAGA ATTGCTGTGA GGAAAAGAGG AATCCCTCCT CCAGCACGCT GCCAGGCGGT 
GGTGTTCAGA ACCCTTCTGC AGACAGGAAT TTGCTGGACC TCCTCTCAGC ACAGCCAGCT 
CCGTGCCCTC TGAATTATGT TTCGCAGAAA AGTGTCCCCA AGGAAGTGCC ACCAGGTACT 
AAGTCCTCTC CAGGTTGGTC CTGGGAGGCT GGCCCGTTGG CTCCTTCCCC ATCTTCACAG 
AATACACCTC TGGCTCAAGT GTTTGTCCCT TTGGAGTCTG TTAAGCCCAG CAGCCTGCCG 
CCTCTCATTG TGTATGACCG GAATGGATTC AGAATTCTGC TCCACTTCTC CCAGACGGGA 
GCCCCTGGGC ACCCAGAGGT ACAGGTGCTG CTCTTGACCA TGATGAGCAC GGCTCCCCAG 
CCTGTCTGGG ATATCATGTT TCAAGTGGCT GTGCCAAAGT CAATGAGAGT GAAGCTGCAG 
CCGGCATCCA GCTCCAAGCT TCCTGCATTC AGTCCTTTGA TGCCTCCAGC TGTGATATCT 
CAGATGCTGC TGCTTGACAA TCCACACAAA GAACCTATCC GCTTACGGTA CAAGCTGACA 
TTCAACCAAG GTGGACAGCC TTTCAGCGAA GTAGGAGAAG TGAAAGACTT CCCAGACCTG 
GCTGTCTTGG GCGCAGCCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

GGA2 interacts with EGFR cytoplasmic domain to stabilize the receptor expression and promote cell growth.
Scientific reports8(1)1368(2018 Jan)
Uemura T,Kametaka S,Waguri S

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Conserved role for Gga proteins in phosphatidylinositol 4-kinase localization to the
Proceedings of the National Academy of Sciences of the United States of America114(13)3433-3438(2017 Mar)
Daboussi L,Costaguta G,Ghukasyan R,Payne GS

Regulation of ?
Scientific reports637921(2016 Nov)
Zhang M,Huang W,Gao J,Terry AV,Wu G

The Golgi-Localized ?-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-? Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1).
PloS one10(6)e0129047(2015)
von Einem B,Wahler A,Schips T,Serrano-Pozo A,Proepper C,Boeckers TM,Rueck A,Wirth T,Hyman BT,Danzer KM,Thal DR,von Arnim CA

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GGA2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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