Gene Symbol | FOXE1 |
Entrez Gene ID | 2304 |
Full Name | forkhead box E1 |
Synonyms | FKHL15,FOXE2,HFKH4,HFKL5,NMTC4,TITF2,TTF-2,TTF2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This intronless gene encodes a protein that belongs to the forkhead family of transcription factors. Members of this family contain a conserved 100-amino acid DNA-binding 'forkhead' domain. The encoded protein functions as a thyroid transcription factor that plays a role in thyroid morphogenesis. Mutations in this gene are associated with the Bamforth-Lazarus syndrome, and with susceptibility to nonmedullary thyroid cancer-4. [provided by RefSeq, Nov 2016]. |
Disorder MIM: | |
Disorder Html: | Bamforth-Lazarus syndrome, 241850 (3); {Thyroid cancer, nonmedullary, 4}, 616534 (3) |