ATF6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ATF6
Entrez Gene ID	22926
Full Name	activating transcription factor 6
Synonyms	ACHM7,ATF6A
General protein information	Preferred Names activating transcription factor 6 Names cyclic AMP-dependent transcription factor ATF-6 alpha cAMP-dependent transcription factor ATF-6 alpha
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q23.3
Summary	This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis. [provided by RefSeq, Aug 2011].
Disorder MIM:	605537
Disorder Html:	Achromatopsia 7, 616517 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_007348.3	NP_031374.2	cyclic AMP-dependent transcription factor ATF-6 alpha
XM_011509310.2	XP_011507612.1	cyclic AMP-dependent transcription factor ATF-6 alpha isoform X4
XM_006711224.1	XP_006711287.1	cyclic AMP-dependent transcription factor ATF-6 alpha isoform X3
XM_011509308.1	XP_011507610.1	cyclic AMP-dependent transcription factor ATF-6 alpha isoform X1
XM_011509309.1	XP_011507611.1	cyclic AMP-dependent transcription factor ATF-6 alpha isoform X2
NM_007348.4	NP_031374.2	cyclic AMP-dependent transcription factor ATF-6 alpha

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Atf6	NP_001074773.1
Gallus gallus (chicken)	ATF6	XP_422208.3
Danio rerio (zebrafish)	atf6	NP_001103989.1
Homo sapiens (human)	ATF6	NP_031374.2
	ATF6	XP_001118153.2
Bos taurus (cattle)	ATF6	XP_003585864.2
Xenopus tropicalis (tropical clawed frog)	atf6	XP_002933826.2
Pan troglodytes (chimpanzee)	ATF6	XP_001174215.1
Canis lupus familiaris (dog)	ATF6	XP_005640918.1
Rattus norvegicus (Norway rat)	Atf6	NP_001100666.1

Gene Ontology
Bibliography

Related articles in PubMed

SUMOylation represses the transcriptional activity of the Unfolded Protein Response transducer ATF6.
Hou X, Yang Z, Zhang K, Fang D, Sun F
Biochemical and biophysical research communications494(3-4)446-451(2017 12)

Divest yourself of a preconceived idea: transcription factor ATF6 is not a soluble protein!
Mori K
Molecular biology of the cell21(9)1435-8(2010 May)

The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels.
Meex SJ, Weissglas-Volkov D, van der Kallen CJ, Thuerauf DJ, van Greevenbroek MM, Schalkwijk CG, Stehouwer CD, Feskens EJ, Heldens L, Ayoubi TA, Hofker MH, Wouters BG, Vlietinck R, Sinsheimer JS, Taskinen MR, Kuusisto J, Laakso M, de Bruin TW, Pajukanta P, Glembotski CC
Arteriosclerosis, thrombosis, and vascular biology29(9)1322-7(2009 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In summary, our study revealed a negative regulation of the UPR transducer ATF6 through post-translational SUMOylation. The information from this study will not only increase our understanding of the fine-tuning regulation of the UPR signaling but will also be informative to the modulation of the UPR for therapeutic benefits.
Title: SUMOylation represses the transcriptional activity of the Unfolded Protein Response transducer ATF6.

Low ATF6 expression is associated with cancer.
Title: Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells.

Activating transcription factor 6 (ATF6alpha) pathway and ER-associated protein degradation (ERAD) are elevated in salivary glands of Sjogren's syndrome patients (SS).
Title: Pro-inflammatory cytokines enhance ERAD and ATF6? pathway activity in salivary glands of Sj?gren's syndrome patients.

A transcription factor complex consisting of ATF6 (an endoplasmic reticulum-resident factor) and C/EBP-beta is required for the IFN-gamma-induced expression of DAPK1 IFN-gamma-induced proteolytic processing of ATF6 and phosphorylation of C/EBP-beta are obligatory for the formation of this transcriptional complex
Title: Death-associated Protein Kinase-1 Expression and Autophagy in Chronic Lymphocytic Leukemia Are Dependent on Activating Transcription Factor-6 and CCAAT/Enhancer-binding Protein-?.

This review shown that the achromatopsia arising from genetic mutations in Activating Transcription Factor 6 (ATF6).
Title: Endoplasmic reticulum stress in human photoreceptor diseases.

The following ATF6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ATF6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20688	NM_007348.4 Latest version!	Homo sapiens activating transcription factor 6 (ATF6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$475.30 $679.00
OHu65143	XM_011509310.2 Latest version!	Homo sapiens activating transcription factor 6 (ATF6), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu34209	XM_006711224.1 Latest version!	Homo sapiens activating transcription factor 6 (ATF6), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu65141	XM_011509308.1 Latest version!	Homo sapiens activating transcription factor 6 (ATF6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu65142	XM_011509309.1 Latest version!	Homo sapiens activating transcription factor 6 (ATF6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
View Old Accession Versions >>
OHu20688	NM_007348.3	Homo sapiens activating transcription factor 6 (ATF6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$475.30 $679.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ATF6 ( NM_007348.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_031374.2 Homo sapiens activating transcription factor 6 (ATF6), mRNA.

Price & Availability↑

CloneID	OHu20688
Clone ID Related Accession (Same CDS sequence)	NM_007348.3 , NM_007348.4
Accession Version	NM_007348.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2013bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-29
Organism	Homo sapiens(human)
Product	cyclic AMP-dependent transcription factor ATF-6 alpha
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP380917.1, BC014969.1, AK290498.1, AB015856.1, AL391825.15 and BM683233.1. This sequence is a reference standard in the RefSeqGene project. On Aug 9, 2011 this sequence version replaced NM_007348.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.169690.1, SRR1803616.102460.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGGAGC CGGCTGGGGT TGCCGGCACC ATGGAGTCAC CTTTTAGCCC GGGACTCTTT 
CACAGGCTGG ATGAAGATTG GGATTCTGCT CTCTTTGCTG AACTCGGTTA TTTCACAGAC 
ACTGATGAGC TGCAATTGGA AGCAGCAAAT GAGACGTATG AAAACAATTT TGATAATCTT 
GATTTTGATT TGGATTTGAT GCCTTGGGAG TCAGACATTT GGGACATCAA CAACCAAATC 
TGTACAGTTA AAGATATTAA GGCAGAACCT CAGCCACTTT CTCCAGCCTC CTCAAGTTAT 
TCAGTCTCGT CTCCTCGGTC AGTGGACTCT TATTCTTCAA CTCAGCATGT TCCTGAGGAG 
TTGGATTTGT CTTCTAGTTC TCAGATGTCT CCCCTTTCCT TATATGGTGA AAACTCTAAT 
AGTCTCTCTT CAGCGGAGCC ACTGAAGGAA GATAAGCCTG TCACTGGTCC TAGGAACAAG 
ACTGAAAATG GACTGACTCC AAAGAAAAAA ATTCAGGTGA ATTCAAAACC TTCAATTCAG 
CCCAAGCCTT TATTGCTTCC AGCAGCACCC AAGACTCAAA CAAACTCCAG TGTTCCAGCA 
AAAACCATCA TTATTCAGAC AGTACCAACG CTTATGCCAT TGGCAAAGCA GCAACCAATT 
ATCAGTTTAC AACCTGCACC CACTAAAGGC CAGACGGTTT TGCTGTCTCA GCCTACTGTG 
GTACAACTTC AAGCACCTGG AGTTCTGCCC TCTGCTCAGC CAGTCCTTGC TGTTGCTGGG 
GGAGTCACAC AGCTCCCTAA TCACGTGGTG AATGTGGTAC CAGCCCCTTC AGCGAATAGC 
CCAGTGAATG GAAAACTTTC CGTGACTAAA CCTGTCCTAC AAAGTACCAT GAGAAATGTC 
GGTTCAGATA TTGCTGTGCT AAGGAGACAG CAACGTATGA TAAAAAATCG AGAATCCGCT 
TGTCAGTCTC GCAAGAAGAA GAAAGAATAT ATGCTAGGGT TAGAGGCGAG ATTAAAGGCT 
GCCCTCTCAG AAAACGAGCA ACTGAAGAAA GAAAATGGAA CACTGAAGCG GCAGCTGGAT 
GAAGTTGTGT CAGAGAACCA GAGGCTTAAA GTCCCTAGTC CAAAGCGAAG AGTTGTCTGT 
GTGATGATAG TATTGGCATT TATAATACTG AACTATGGAC CTATGAGCAT GTTGGAACAG 
GATTCCAGGA GAATGAACCC TAGTGTGAGC CCTGCAAATC AAAGGAGGCA CCTTCTAGGA 
TTTTCTGCTA AAGAGGCACA GGACACATCA GATGGTATTA TCCAGAAAAA CAGCTACAGA 
TATGATCATT CTGTTTCAAA TGACAAAGCC CTGATGGTGC TAACTGAAGA ACCATTGCTT 
TACATTCCTC CACCTCCTTG TCAGCCCCTA ATTAACACAA CAGAGTCTCT CAGGTTAAAT 
CATGAACTTC GAGGATGGGT TCATAGACAT GAAGTAGAAA GGACCAAGTC AAGAAGAATG 
ACAAATAATC AACAGAAAAC CCGTATTCTT CAGGGTGCTC TGGAACAGGG CTCAAATTCT 
CAGCTGATGG CTGTTCAATA CACAGAAACC ACTAGTAGTA TCAGCAGGAA CTCAGGGAGT 
GAGCTACAAG TGTATTATGC TTCACCCAGA AGTTATCAAG ACTTTTTTGA AGCCATCCGC 
AGAAGGGGAG ACACATTTTA TGTTGTGTCA TTTCGAAGGG ATCACCTGCT GTTACCAGCT 
ACCACCCATA ACAAGACCAC AAGACCAAAA ATGTCAATTG TGTTACCAGC AATAAACATA 
AATGAGAATG TGATCAATGG GCAGGACTAC GAAGTGATGA TGCAGATTGA CTGTCAGGTG 
ATGGACACCA GGATCCTCCA TATCAAAAGT TCGTCAGTTC CTCCTTACCT CCGAGATCAG 
CAGAGGAATC AAACCAACAC CTTCTTTGGC TCCCCTCCCG CAGCCACAGA GGCAACCCAC 
GTTGTCAGCA CCATCCCTGA GTCATTACAA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031374.2
CDS	118..2130
Translation	MGEPAGVAGTMESPFSPGLFHRLDEDWDSALFAELGYFTDTDELQLEAANETYENNFDNLDFDLDLMPWESDIWDINNQICTVKDIKAEPQPLSPASSSYSVSSPRSVDSYSSTQHVPEELDLSSSSQMSPLSLYGENSNSLSSAEPLKEDKPVTGPRNKTENGLTPKKKIQVNSKPSIQPKPLLLPAAPKTQTNSSVPAKTIIIQTVPTLMPLAKQQPIISLQPAPTKGQTVLLSQPTVVQLQAPGVLPSAQPVLAVAGGVTQLPNHVVNVVPAPSANSPVNGKLSVTKPVLQSTMRNVGSDIAVLRRQQRMIKNRESACQSRKKKKEYMLGLEARLKAALSENEQLKKENGTLKRQLDEVVSENQRLKVPSPKRRVVCVMIVLAFIILNYGPMSMLEQDSRRMNPSVSPANQRRHLLGFSAKEAQDTSDGIIQKNSYRYDHSVSNDKALMVLTEEPLLYIPPPPCQPLINTTESLRLNHELRGWVHRHEVERTKSRRMTNNQQKTRILQGALEQGSNSQLMAVQYTETTSSISRNSGSELQVYYASPRSYQDFFEAIRRRGDTFYVVSFRRDHLLLPATTHNKTTRPKMSIVLPAININENVINGQDYEVMMQIDCQVMDTRILHIKSSSVPPYLRDQQRNQTNTFFGSPPAATEATHVVSTIPESLQ

Target ORF information:

RefSeq Version	NM_007348.3
Organism	Homo sapiens(human)
Definition	Homo sapiens activating transcription factor 6 (ATF6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007348.3

ORF Insert Sequence:

ATGGGGGAGC CGGCTGGGGT TGCCGGCACC ATGGAGTCAC CTTTTAGCCC GGGACTCTTT 
CACAGGCTGG ATGAAGATTG GGATTCTGCT CTCTTTGCTG AACTCGGTTA TTTCACAGAC 
ACTGATGAGC TGCAATTGGA AGCAGCAAAT GAGACGTATG AAAACAATTT TGATAATCTT 
GATTTTGATT TGGATTTGAT GCCTTGGGAG TCAGACATTT GGGACATCAA CAACCAAATC 
TGTACAGTTA AAGATATTAA GGCAGAACCT CAGCCACTTT CTCCAGCCTC CTCAAGTTAT 
TCAGTCTCGT CTCCTCGGTC AGTGGACTCT TATTCTTCAA CTCAGCATGT TCCTGAGGAG 
TTGGATTTGT CTTCTAGTTC TCAGATGTCT CCCCTTTCCT TATATGGTGA AAACTCTAAT 
AGTCTCTCTT CAGCGGAGCC ACTGAAGGAA GATAAGCCTG TCACTGGTCC TAGGAACAAG 
ACTGAAAATG GACTGACTCC AAAGAAAAAA ATTCAGGTGA ATTCAAAACC TTCAATTCAG 
CCCAAGCCTT TATTGCTTCC AGCAGCACCC AAGACTCAAA CAAACTCCAG TGTTCCAGCA 
AAAACCATCA TTATTCAGAC AGTACCAACG CTTATGCCAT TGGCAAAGCA GCAACCAATT 
ATCAGTTTAC AACCTGCACC CACTAAAGGC CAGACGGTTT TGCTGTCTCA GCCTACTGTG 
GTACAACTTC AAGCACCTGG AGTTCTGCCC TCTGCTCAGC CAGTCCTTGC TGTTGCTGGG 
GGAGTCACAC AGCTCCCTAA TCACGTGGTG AATGTGGTAC CAGCCCCTTC AGCGAATAGC 
CCAGTGAATG GAAAACTTTC CGTGACTAAA CCTGTCCTAC AAAGTACCAT GAGAAATGTC 
GGTTCAGATA TTGCTGTGCT AAGGAGACAG CAACGTATGA TAAAAAATCG AGAATCCGCT 
TGTCAGTCTC GCAAGAAGAA GAAAGAATAT ATGCTAGGGT TAGAGGCGAG ATTAAAGGCT 
GCCCTCTCAG AAAACGAGCA ACTGAAGAAA GAAAATGGAA CACTGAAGCG GCAGCTGGAT 
GAAGTTGTGT CAGAGAACCA GAGGCTTAAA GTCCCTAGTC CAAAGCGAAG AGTTGTCTGT 
GTGATGATAG TATTGGCATT TATAATACTG AACTATGGAC CTATGAGCAT GTTGGAACAG 
GATTCCAGGA GAATGAACCC TAGTGTGAGC CCTGCAAATC AAAGGAGGCA CCTTCTAGGA 
TTTTCTGCTA AAGAGGCACA GGACACATCA GATGGTATTA TCCAGAAAAA CAGCTACAGA 
TATGATCATT CTGTTTCAAA TGACAAAGCC CTGATGGTGC TAACTGAAGA ACCATTGCTT 
TACATTCCTC CACCTCCTTG TCAGCCCCTA ATTAACACAA CAGAGTCTCT CAGGTTAAAT 
CATGAACTTC GAGGATGGGT TCATAGACAT GAAGTAGAAA GGACCAAGTC AAGAAGAATG 
ACAAATAATC AACAGAAAAC CCGTATTCTT CAGGGTGCTC TGGAACAGGG CTCAAATTCT 
CAGCTGATGG CTGTTCAATA CACAGAAACC ACTAGTAGTA TCAGCAGGAA CTCAGGGAGT 
GAGCTACAAG TGTATTATGC TTCACCCAGA AGTTATCAAG ACTTTTTTGA AGCCATCCGC 
AGAAGGGGAG ACACATTTTA TGTTGTGTCA TTTCGAAGGG ATCACCTGCT GTTACCAGCT 
ACCACCCATA ACAAGACCAC AAGACCAAAA ATGTCAATTG TGTTACCAGC AATAAACATA 
AATGAGAATG TGATCAATGG GCAGGACTAC GAAGTGATGA TGCAGATTGA CTGTCAGGTG 
ATGGACACCA GGATCCTCCA TATCAAAAGT TCGTCAGTTC CTCCTTACCT CCGAGATCAG 
CAGAGGAATC AAACCAACAC CTTCTTTGGC TCCCCTCCCG CAGCCACAGA GGCAACCCAC 
GTTGTCAGCA CCATCCCTGA GTCATTACAA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATF6 ( NM_007348.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_031374.2 Homo sapiens activating transcription factor 6 (ATF6), mRNA.

Price & Availability↑

CloneID	OHu20688
Clone ID Related Accession (Same CDS sequence)	NM_007348.3 , NM_007348.4
Accession Version	NM_007348.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2013bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	cyclic AMP-dependent transcription factor ATF-6 alpha
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP380917.1, BC014969.1, AK290498.1, AB015856.1, AL391825.15 and BM683233.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_007348.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.251467.1, SRR1803616.102460.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000367942.4/ ENSP00000356919.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGGAGC CGGCTGGGGT TGCCGGCACC ATGGAGTCAC CTTTTAGCCC GGGACTCTTT 
CACAGGCTGG ATGAAGATTG GGATTCTGCT CTCTTTGCTG AACTCGGTTA TTTCACAGAC 
ACTGATGAGC TGCAATTGGA AGCAGCAAAT GAGACGTATG AAAACAATTT TGATAATCTT 
GATTTTGATT TGGATTTGAT GCCTTGGGAG TCAGACATTT GGGACATCAA CAACCAAATC 
TGTACAGTTA AAGATATTAA GGCAGAACCT CAGCCACTTT CTCCAGCCTC CTCAAGTTAT 
TCAGTCTCGT CTCCTCGGTC AGTGGACTCT TATTCTTCAA CTCAGCATGT TCCTGAGGAG 
TTGGATTTGT CTTCTAGTTC TCAGATGTCT CCCCTTTCCT TATATGGTGA AAACTCTAAT 
AGTCTCTCTT CAGCGGAGCC ACTGAAGGAA GATAAGCCTG TCACTGGTCC TAGGAACAAG 
ACTGAAAATG GACTGACTCC AAAGAAAAAA ATTCAGGTGA ATTCAAAACC TTCAATTCAG 
CCCAAGCCTT TATTGCTTCC AGCAGCACCC AAGACTCAAA CAAACTCCAG TGTTCCAGCA 
AAAACCATCA TTATTCAGAC AGTACCAACG CTTATGCCAT TGGCAAAGCA GCAACCAATT 
ATCAGTTTAC AACCTGCACC CACTAAAGGC CAGACGGTTT TGCTGTCTCA GCCTACTGTG 
GTACAACTTC AAGCACCTGG AGTTCTGCCC TCTGCTCAGC CAGTCCTTGC TGTTGCTGGG 
GGAGTCACAC AGCTCCCTAA TCACGTGGTG AATGTGGTAC CAGCCCCTTC AGCGAATAGC 
CCAGTGAATG GAAAACTTTC CGTGACTAAA CCTGTCCTAC AAAGTACCAT GAGAAATGTC 
GGTTCAGATA TTGCTGTGCT AAGGAGACAG CAACGTATGA TAAAAAATCG AGAATCCGCT 
TGTCAGTCTC GCAAGAAGAA GAAAGAATAT ATGCTAGGGT TAGAGGCGAG ATTAAAGGCT 
GCCCTCTCAG AAAACGAGCA ACTGAAGAAA GAAAATGGAA CACTGAAGCG GCAGCTGGAT 
GAAGTTGTGT CAGAGAACCA GAGGCTTAAA GTCCCTAGTC CAAAGCGAAG AGTTGTCTGT 
GTGATGATAG TATTGGCATT TATAATACTG AACTATGGAC CTATGAGCAT GTTGGAACAG 
GATTCCAGGA GAATGAACCC TAGTGTGAGC CCTGCAAATC AAAGGAGGCA CCTTCTAGGA 
TTTTCTGCTA AAGAGGCACA GGACACATCA GATGGTATTA TCCAGAAAAA CAGCTACAGA 
TATGATCATT CTGTTTCAAA TGACAAAGCC CTGATGGTGC TAACTGAAGA ACCATTGCTT 
TACATTCCTC CACCTCCTTG TCAGCCCCTA ATTAACACAA CAGAGTCTCT CAGGTTAAAT 
CATGAACTTC GAGGATGGGT TCATAGACAT GAAGTAGAAA GGACCAAGTC AAGAAGAATG 
ACAAATAATC AACAGAAAAC CCGTATTCTT CAGGGTGCTC TGGAACAGGG CTCAAATTCT 
CAGCTGATGG CTGTTCAATA CACAGAAACC ACTAGTAGTA TCAGCAGGAA CTCAGGGAGT 
GAGCTACAAG TGTATTATGC TTCACCCAGA AGTTATCAAG ACTTTTTTGA AGCCATCCGC 
AGAAGGGGAG ACACATTTTA TGTTGTGTCA TTTCGAAGGG ATCACCTGCT GTTACCAGCT 
ACCACCCATA ACAAGACCAC AAGACCAAAA ATGTCAATTG TGTTACCAGC AATAAACATA 
AATGAGAATG TGATCAATGG GCAGGACTAC GAAGTGATGA TGCAGATTGA CTGTCAGGTG 
ATGGACACCA GGATCCTCCA TATCAAAAGT TCGTCAGTTC CTCCTTACCT CCGAGATCAG 
CAGAGGAATC AAACCAACAC CTTCTTTGGC TCCCCTCCCG CAGCCACAGA GGCAACCCAC 
GTTGTCAGCA CCATCCCTGA GTCATTACAA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_031374.2
CDS	42..2054
Translation	MGEPAGVAGTMESPFSPGLFHRLDEDWDSALFAELGYFTDTDELQLEAANETYENNFDNLDFDLDLMPWESDIWDINNQICTVKDIKAEPQPLSPASSSYSVSSPRSVDSYSSTQHVPEELDLSSSSQMSPLSLYGENSNSLSSAEPLKEDKPVTGPRNKTENGLTPKKKIQVNSKPSIQPKPLLLPAAPKTQTNSSVPAKTIIIQTVPTLMPLAKQQPIISLQPAPTKGQTVLLSQPTVVQLQAPGVLPSAQPVLAVAGGVTQLPNHVVNVVPAPSANSPVNGKLSVTKPVLQSTMRNVGSDIAVLRRQQRMIKNRESACQSRKKKKEYMLGLEARLKAALSENEQLKKENGTLKRQLDEVVSENQRLKVPSPKRRVVCVMIVLAFIILNYGPMSMLEQDSRRMNPSVSPANQRRHLLGFSAKEAQDTSDGIIQKNSYRYDHSVSNDKALMVLTEEPLLYIPPPPCQPLINTTESLRLNHELRGWVHRHEVERTKSRRMTNNQQKTRILQGALEQGSNSQLMAVQYTETTSSISRNSGSELQVYYASPRSYQDFFEAIRRRGDTFYVVSFRRDHLLLPATTHNKTTRPKMSIVLPAININENVINGQDYEVMMQIDCQVMDTRILHIKSSSVPPYLRDQQRNQTNTFFGSPPAATEATHVVSTIPESLQ

Target ORF information:

RefSeq Version	NM_007348.4
Organism	Homo sapiens(human)
Definition	Homo sapiens activating transcription factor 6 (ATF6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007348.4

ORF Insert Sequence:

ATGGGGGAGC CGGCTGGGGT TGCCGGCACC ATGGAGTCAC CTTTTAGCCC GGGACTCTTT 
CACAGGCTGG ATGAAGATTG GGATTCTGCT CTCTTTGCTG AACTCGGTTA TTTCACAGAC 
ACTGATGAGC TGCAATTGGA AGCAGCAAAT GAGACGTATG AAAACAATTT TGATAATCTT 
GATTTTGATT TGGATTTGAT GCCTTGGGAG TCAGACATTT GGGACATCAA CAACCAAATC 
TGTACAGTTA AAGATATTAA GGCAGAACCT CAGCCACTTT CTCCAGCCTC CTCAAGTTAT 
TCAGTCTCGT CTCCTCGGTC AGTGGACTCT TATTCTTCAA CTCAGCATGT TCCTGAGGAG 
TTGGATTTGT CTTCTAGTTC TCAGATGTCT CCCCTTTCCT TATATGGTGA AAACTCTAAT 
AGTCTCTCTT CAGCGGAGCC ACTGAAGGAA GATAAGCCTG TCACTGGTCC TAGGAACAAG 
ACTGAAAATG GACTGACTCC AAAGAAAAAA ATTCAGGTGA ATTCAAAACC TTCAATTCAG 
CCCAAGCCTT TATTGCTTCC AGCAGCACCC AAGACTCAAA CAAACTCCAG TGTTCCAGCA 
AAAACCATCA TTATTCAGAC AGTACCAACG CTTATGCCAT TGGCAAAGCA GCAACCAATT 
ATCAGTTTAC AACCTGCACC CACTAAAGGC CAGACGGTTT TGCTGTCTCA GCCTACTGTG 
GTACAACTTC AAGCACCTGG AGTTCTGCCC TCTGCTCAGC CAGTCCTTGC TGTTGCTGGG 
GGAGTCACAC AGCTCCCTAA TCACGTGGTG AATGTGGTAC CAGCCCCTTC AGCGAATAGC 
CCAGTGAATG GAAAACTTTC CGTGACTAAA CCTGTCCTAC AAAGTACCAT GAGAAATGTC 
GGTTCAGATA TTGCTGTGCT AAGGAGACAG CAACGTATGA TAAAAAATCG AGAATCCGCT 
TGTCAGTCTC GCAAGAAGAA GAAAGAATAT ATGCTAGGGT TAGAGGCGAG ATTAAAGGCT 
GCCCTCTCAG AAAACGAGCA ACTGAAGAAA GAAAATGGAA CACTGAAGCG GCAGCTGGAT 
GAAGTTGTGT CAGAGAACCA GAGGCTTAAA GTCCCTAGTC CAAAGCGAAG AGTTGTCTGT 
GTGATGATAG TATTGGCATT TATAATACTG AACTATGGAC CTATGAGCAT GTTGGAACAG 
GATTCCAGGA GAATGAACCC TAGTGTGAGC CCTGCAAATC AAAGGAGGCA CCTTCTAGGA 
TTTTCTGCTA AAGAGGCACA GGACACATCA GATGGTATTA TCCAGAAAAA CAGCTACAGA 
TATGATCATT CTGTTTCAAA TGACAAAGCC CTGATGGTGC TAACTGAAGA ACCATTGCTT 
TACATTCCTC CACCTCCTTG TCAGCCCCTA ATTAACACAA CAGAGTCTCT CAGGTTAAAT 
CATGAACTTC GAGGATGGGT TCATAGACAT GAAGTAGAAA GGACCAAGTC AAGAAGAATG 
ACAAATAATC AACAGAAAAC CCGTATTCTT CAGGGTGCTC TGGAACAGGG CTCAAATTCT 
CAGCTGATGG CTGTTCAATA CACAGAAACC ACTAGTAGTA TCAGCAGGAA CTCAGGGAGT 
GAGCTACAAG TGTATTATGC TTCACCCAGA AGTTATCAAG ACTTTTTTGA AGCCATCCGC 
AGAAGGGGAG ACACATTTTA TGTTGTGTCA TTTCGAAGGG ATCACCTGCT GTTACCAGCT 
ACCACCCATA ACAAGACCAC AAGACCAAAA ATGTCAATTG TGTTACCAGC AATAAACATA 
AATGAGAATG TGATCAATGG GCAGGACTAC GAAGTGATGA TGCAGATTGA CTGTCAGGTG 
ATGGACACCA GGATCCTCCA TATCAAAAGT TCGTCAGTTC CTCCTTACCT CCGAGATCAG 
CAGAGGAATC AAACCAACAC CTTCTTTGGC TCCCCTCCCG CAGCCACAGA GGCAACCCAC 
GTTGTCAGCA CCATCCCTGA GTCATTACAA TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATF6 ( XM_011509310.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011507612.1 Homo sapiens activating transcription factor 6 (ATF6), transcript variant X4, mRNA.

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CloneID	OHu65143
Clone ID Related Accession (Same CDS sequence)	XM_011509310.2
Accession Version	XM_011509310.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1788bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cyclic AMP-dependent transcription factor ATF-6 alpha isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011509310.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGGAGC CGGCTGGGGT TGCCGGCACC ATGGAGTCAC CTTTTAGCCC GGGACTCTTT 
CACAGGCTGG ATGAAGATTG GGATTCTGCT CTCTTTGCTG AACTCGGTTA TTTCACAGAC 
ACTGATGAGC TGCAATTGGA AGCAGCAAAT GAGACGTATG AAAACAATTT TGATAATCTT 
GATTTTGATT TGGATTTGAT GCCTTGGGAG TCAGACATTT GGGACATCAA CAACCAAATC 
TGTACAGTTA AAGATATTAA GGCAGAACCT CAGCCACTTT CTCCAGCCTC CTCAAGTTAT 
TCAGTCTCGT CTCCTCGGTC AGTGGACTCT TATTCTTCAA CTCAGCATGT TCCTGAGGAG 
TTGGATTTGT CTTCTAGTTC TCAGATGTCT CCCCTTTCCT TATATGGTGA AAACTCTAAT 
AGTCTCTCTT CAGCGGAGCC ACTGAAGGAA GATAAGCCTG TCACTGGTCC TAGGAACAAG 
ACTGAAAATG GACTGACTCC AAAGAAAAAA ATTCAGGTGA ATTCAAAACC TTCAATTCAG 
CCCAAGCCTT TATTGCTTCC AGCAGCACCC AAGACTCAAA CAAACTCCAG TGTTCCAGCA 
AAAACCATCA TTATTCAGAC AGTACCAACG CTTATGCCAT TGGCAAAGCA GCAACCAATT 
ATCAGTTTAC AACCTGCACC CACTAAAGGC CAGACGGTTT TGCTGTCTCA GCCTACTGTG 
GTACAACTTC AAGCACCTGG AGTTCTGCCC TCTGCTCAGC CAGTCCTTGC TGTTGCTGGG 
GGAGTCACAC AGCTCCCTAA TCACGTGGTG AATGTGGTAC CAGCCCCTTC AGCGAATAGC 
CCAGTGAATG GAAAACTTTC CGTGACTAAA CCTGTCCTAC AAAGTACCAT GAGAAATGTC 
GGTTCAGATA TTGCTGTGCT AAGGAGACAG CAACGTATGA TAAAAAATCG AGAATCCGCT 
TGTCAGTCTC GCAAGAAGAA GAAAGAATAT ATGCTAGGGT TAGAGGCGAG ATTAAAGGCT 
GCCCTCTCAG AAAACGAGCA ACTGAAGAAA GAAAATGGAA CACTGAAGCG GCAGCTGGAT 
GAAGTTGTGT CAGAGAACCA GAGGCTTAAA GTCCCTAGTC CAAAGCGAAG AGTTGTCTGT 
GTGATGATAG TATTGGCATT TATAATACTG AACTATGGAC CTATGAGCAT GTTGGAACAG 
GATTCCAGGA GAATGAACCC TAGTGTGAGC CCTGCAAATC AAAGGAGGCA CCTTCTAGGA 
TTTTCTGCTA AAGAGGCACA GGACACATCA GATGGTATTA TCCAGAAAAA CAGCTACAGC 
AAACTTCTTA GGAATTTAAG ATACAAGGAA ACAAATTTTG TGCATCCATG TTTCAGATAT 
GATCATTCTG TTTCAAATGA CAAAGCCCTG ATGGTGCTAA CTGAAGAACC ATTGCTTTAC 
ATTCCTCCAC CTCCTTGTCA GCCCCTAATT AACACAACAG AGTCTCTCAG GTTAAATCAT 
GAACTTCGAG GATGGGTTCA TAGACATGAA GTAGAAAGGA CCAAGTCAAG AAGAATGACA 
AATAATCAAC AGAAAACCCG TATTCTTCAG GGTGCTCTGG AACAGGGCTC AAATTCTCAG 
CTGATGGCTG TTCAATACAC AGAAACCACT AGTAGTATCA GCAGGAACTC AGGGAGTGAG 
CTACAAGTGT ATTATGCTTC ACCCAGAAGT TATCAAGACT TTTTTGAAGC CATCCGCAGA 
AGGGGAGACA CATTTTATGT TGTGTCATTT CGAAGGTTGA GCGGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011507612.1
CDS	42..1829
Translation	MGEPAGVAGTMESPFSPGLFHRLDEDWDSALFAELGYFTDTDELQLEAANETYENNFDNLDFDLDLMPWESDIWDINNQICTVKDIKAEPQPLSPASSSYSVSSPRSVDSYSSTQHVPEELDLSSSSQMSPLSLYGENSNSLSSAEPLKEDKPVTGPRNKTENGLTPKKKIQVNSKPSIQPKPLLLPAAPKTQTNSSVPAKTIIIQTVPTLMPLAKQQPIISLQPAPTKGQTVLLSQPTVVQLQAPGVLPSAQPVLAVAGGVTQLPNHVVNVVPAPSANSPVNGKLSVTKPVLQSTMRNVGSDIAVLRRQQRMIKNRESACQSRKKKKEYMLGLEARLKAALSENEQLKKENGTLKRQLDEVVSENQRLKVPSPKRRVVCVMIVLAFIILNYGPMSMLEQDSRRMNPSVSPANQRRHLLGFSAKEAQDTSDGIIQKNSYSKLLRNLRYKETNFVHPCFRYDHSVSNDKALMVLTEEPLLYIPPPPCQPLINTTESLRLNHELRGWVHRHEVERTKSRRMTNNQQKTRILQGALEQGSNSQLMAVQYTETTSSISRNSGSELQVYYASPRSYQDFFEAIRRRGDTFYVVSFRRLSG

Target ORF information:

RefSeq Version	XM_011509310.2
Organism	Homo sapiens(human)
Definition	Homo sapiens activating transcription factor 6 (ATF6), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011509310.2

ORF Insert Sequence:

ATGGGGGAGC CGGCTGGGGT TGCCGGCACC ATGGAGTCAC CTTTTAGCCC GGGACTCTTT 
CACAGGCTGG ATGAAGATTG GGATTCTGCT CTCTTTGCTG AACTCGGTTA TTTCACAGAC 
ACTGATGAGC TGCAATTGGA AGCAGCAAAT GAGACGTATG AAAACAATTT TGATAATCTT 
GATTTTGATT TGGATTTGAT GCCTTGGGAG TCAGACATTT GGGACATCAA CAACCAAATC 
TGTACAGTTA AAGATATTAA GGCAGAACCT CAGCCACTTT CTCCAGCCTC CTCAAGTTAT 
TCAGTCTCGT CTCCTCGGTC AGTGGACTCT TATTCTTCAA CTCAGCATGT TCCTGAGGAG 
TTGGATTTGT CTTCTAGTTC TCAGATGTCT CCCCTTTCCT TATATGGTGA AAACTCTAAT 
AGTCTCTCTT CAGCGGAGCC ACTGAAGGAA GATAAGCCTG TCACTGGTCC TAGGAACAAG 
ACTGAAAATG GACTGACTCC AAAGAAAAAA ATTCAGGTGA ATTCAAAACC TTCAATTCAG 
CCCAAGCCTT TATTGCTTCC AGCAGCACCC AAGACTCAAA CAAACTCCAG TGTTCCAGCA 
AAAACCATCA TTATTCAGAC AGTACCAACG CTTATGCCAT TGGCAAAGCA GCAACCAATT 
ATCAGTTTAC AACCTGCACC CACTAAAGGC CAGACGGTTT TGCTGTCTCA GCCTACTGTG 
GTACAACTTC AAGCACCTGG AGTTCTGCCC TCTGCTCAGC CAGTCCTTGC TGTTGCTGGG 
GGAGTCACAC AGCTCCCTAA TCACGTGGTG AATGTGGTAC CAGCCCCTTC AGCGAATAGC 
CCAGTGAATG GAAAACTTTC CGTGACTAAA CCTGTCCTAC AAAGTACCAT GAGAAATGTC 
GGTTCAGATA TTGCTGTGCT AAGGAGACAG CAACGTATGA TAAAAAATCG AGAATCCGCT 
TGTCAGTCTC GCAAGAAGAA GAAAGAATAT ATGCTAGGGT TAGAGGCGAG ATTAAAGGCT 
GCCCTCTCAG AAAACGAGCA ACTGAAGAAA GAAAATGGAA CACTGAAGCG GCAGCTGGAT 
GAAGTTGTGT CAGAGAACCA GAGGCTTAAA GTCCCTAGTC CAAAGCGAAG AGTTGTCTGT 
GTGATGATAG TATTGGCATT TATAATACTG AACTATGGAC CTATGAGCAT GTTGGAACAG 
GATTCCAGGA GAATGAACCC TAGTGTGAGC CCTGCAAATC AAAGGAGGCA CCTTCTAGGA 
TTTTCTGCTA AAGAGGCACA GGACACATCA GATGGTATTA TCCAGAAAAA CAGCTACAGC 
AAACTTCTTA GGAATTTAAG ATACAAGGAA ACAAATTTTG TGCATCCATG TTTCAGATAT 
GATCATTCTG TTTCAAATGA CAAAGCCCTG ATGGTGCTAA CTGAAGAACC ATTGCTTTAC 
ATTCCTCCAC CTCCTTGTCA GCCCCTAATT AACACAACAG AGTCTCTCAG GTTAAATCAT 
GAACTTCGAG GATGGGTTCA TAGACATGAA GTAGAAAGGA CCAAGTCAAG AAGAATGACA 
AATAATCAAC AGAAAACCCG TATTCTTCAG GGTGCTCTGG AACAGGGCTC AAATTCTCAG 
CTGATGGCTG TTCAATACAC AGAAACCACT AGTAGTATCA GCAGGAACTC AGGGAGTGAG 
CTACAAGTGT ATTATGCTTC ACCCAGAAGT TATCAAGACT TTTTTGAAGC CATCCGCAGA 
AGGGGAGACA CATTTTATGT TGTGTCATTT CGAAGGTTGA GCGGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATF6 ( XM_006711224.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_006711287.1 Homo sapiens activating transcription factor 6 (ATF6), transcript variant X3, mRNA.

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CloneID	OHu34209
Clone ID Related Accession (Same CDS sequence)	XM_006711224.1
Accession Version	XM_006711224.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2010bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cyclic AMP-dependent transcription factor ATF-6 alpha isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGGAGC CGGCTGGGGT TGCCGGCACC ATGGAGTCAC CTTTTAGCCC GGGACTCTTT 
CACAGGCTGG ATGAAGATTG GGATTCTGCT CTCTTTGCTG AACTCGGTTA TTTCACAGAC 
ACTGATGAGC TGCAATTGGA AGCAGCAAAT GAGACGTATG AAAACAATTT TGATAATCTT 
GATTTTGATT TGGATTTGAT GCCTTGGGAG TCAGACATTT GGGACATCAA CAACCAAATC 
TGTACAGTTA AAGATATTAA GGCAGAACCT CAGCCACTTT CTCCAGCCTC CTCAAGTTAT 
TCAGTCTCGT CTCCTCGGTC AGTGGACTCT TATTCTTCAA CTCAGCATGT TCCTGAGGAG 
TTGGATTTGT CTTCTAGTTC TCAGATGTCT CCCCTTTCCT TATATGGTGA AAACTCTAAT 
AGTCTCTCTT CAGCGGAGCC ACTGAAGGAA GATAAGCCTG TCACTGGTCC TAGGAACAAG 
ACTGAAAATG GACTGACTCC AAAGAAAAAA ATTCAGGTGA ATTCAAAACC TTCAATTCAG 
CCCAAGCCTT TATTGCTTCC AGCAGCACCC AAGACTCAAA CAAACTCCAG TGTTCCAGCA 
AAAACCATCA TTATTCAGAC AGTACCAACG CTTATGCCAT TGGCAAAGCA GCAACCAATT 
ATCAGTTTAC AACCTGCACC CACTAAAGGC CAGACGGTTT TGCTGTCTCA GCCTACTGTG 
GTACAACTTC AAGCACCTGG AGTTCTGCCC TCTGCTCAGC CAGTCCTTGC TGTTGCTGGG 
GGAGTCACAC AGCTCCCTAA TCACGTGGTG AATGTGGTAC CAGCCCCTTC AGCGAATAGC 
CCAGTGAATG GAAAACTTTC CGTGACTAAA CCTGTCCTAC AAAGTACCAT GAGAAATGTC 
GGTTCAGATA TTGCTGTGCT AAGGAGACAG CAACGTATGA TAAAAAATCG AGAATCCGCT 
TGTCAGTCTC GCAAGAAGAA GAAAGAATAT ATGCTAGGGT TAGAGGCGAG ATTAAAGGCT 
GCCCTCTCAG AAAACGAGCA ACTGAAGAAA GAAAATGGAA CACTGAAGCG GCAGCTGGAT 
GAAGTTGTGT CAGAGAACCA GAGGCTTAAA GTCCCTAGTC CAAAGCGAAG AGTTGTCTGT 
GTGATGATAG TATTGGCATT TATAATACTG AACTATGGAC CTATGAGCAT GTTGGAACAG 
GATTCCAGGA GAATGAACCC TAGTGTGAGC CCTGCAAATC AAAGGAGGCA CCTTCTAGGA 
TTTTCTGCTA AAGAGGCACA GGACACATCA GATGGTATTA TCCAGAAAAA CAGCTACAGA 
TATGATCATT CTGTTTCAAA TGACAAAGCC CTGATGGTGC TAACTGAAGA ACCATTGCTT 
TACATTCCTC CACCTCCTTG TCAGCCCCTA ATTAACACAA CAGAGTCTCT CAGGTTAAAT 
CATGAACTTC GAGGATGGGT TCATAGACAT GAAGTAGAAA GGACCAAGTC AAGAAGAATG 
ACAAATAATC AACAGAAAAC CCGTATTCTT CAGGGTGCTC TGGAACAGGG CTCAAATTCT 
CAGCTGATGG CTGTTCAATA CACAGAAACC ACTAGTAGTA TCAGGAACTC AGGGAGTGAG 
CTACAAGTGT ATTATGCTTC ACCCAGAAGT TATCAAGACT TTTTTGAAGC CATCCGCAGA 
AGGGGAGACA CATTTTATGT TGTGTCATTT CGAAGGGATC ACCTGCTGTT ACCAGCTACC 
ACCCATAACA AGACCACAAG ACCAAAAATG TCAATTGTGT TACCAGCAAT AAACATAAAT 
GAGAATGTGA TCAATGGGCA GGACTACGAA GTGATGATGC AGATTGACTG TCAGGTGATG 
GACACCAGGA TCCTCCATAT CAAAAGTTCG TCAGTTCCTC CTTACCTCCG AGATCAGCAG 
AGGAATCAAA CCAACACCTT CTTTGGCTCC CCTCCCGCAG CCACAGAGGC AACCCACGTT 
GTCAGCACCA TCCCTGAGTC ATTACAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006711287.1
CDS	42..2051
Translation	MGEPAGVAGTMESPFSPGLFHRLDEDWDSALFAELGYFTDTDELQLEAANETYENNFDNLDFDLDLMPWESDIWDINNQICTVKDIKAEPQPLSPASSSYSVSSPRSVDSYSSTQHVPEELDLSSSSQMSPLSLYGENSNSLSSAEPLKEDKPVTGPRNKTENGLTPKKKIQVNSKPSIQPKPLLLPAAPKTQTNSSVPAKTIIIQTVPTLMPLAKQQPIISLQPAPTKGQTVLLSQPTVVQLQAPGVLPSAQPVLAVAGGVTQLPNHVVNVVPAPSANSPVNGKLSVTKPVLQSTMRNVGSDIAVLRRQQRMIKNRESACQSRKKKKEYMLGLEARLKAALSENEQLKKENGTLKRQLDEVVSENQRLKVPSPKRRVVCVMIVLAFIILNYGPMSMLEQDSRRMNPSVSPANQRRHLLGFSAKEAQDTSDGIIQKNSYRYDHSVSNDKALMVLTEEPLLYIPPPPCQPLINTTESLRLNHELRGWVHRHEVERTKSRRMTNNQQKTRILQGALEQGSNSQLMAVQYTETTSSIRNSGSELQVYYASPRSYQDFFEAIRRRGDTFYVVSFRRDHLLLPATTHNKTTRPKMSIVLPAININENVINGQDYEVMMQIDCQVMDTRILHIKSSSVPPYLRDQQRNQTNTFFGSPPAATEATHVVSTIPESLQ

Target ORF information:

RefSeq Version	XM_006711224.1
Organism	Homo sapiens(human)
Definition	Homo sapiens activating transcription factor 6 (ATF6), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006711224.1

ORF Insert Sequence:

ATGGGGGAGC CGGCTGGGGT TGCCGGCACC ATGGAGTCAC CTTTTAGCCC GGGACTCTTT 
CACAGGCTGG ATGAAGATTG GGATTCTGCT CTCTTTGCTG AACTCGGTTA TTTCACAGAC 
ACTGATGAGC TGCAATTGGA AGCAGCAAAT GAGACGTATG AAAACAATTT TGATAATCTT 
GATTTTGATT TGGATTTGAT GCCTTGGGAG TCAGACATTT GGGACATCAA CAACCAAATC 
TGTACAGTTA AAGATATTAA GGCAGAACCT CAGCCACTTT CTCCAGCCTC CTCAAGTTAT 
TCAGTCTCGT CTCCTCGGTC AGTGGACTCT TATTCTTCAA CTCAGCATGT TCCTGAGGAG 
TTGGATTTGT CTTCTAGTTC TCAGATGTCT CCCCTTTCCT TATATGGTGA AAACTCTAAT 
AGTCTCTCTT CAGCGGAGCC ACTGAAGGAA GATAAGCCTG TCACTGGTCC TAGGAACAAG 
ACTGAAAATG GACTGACTCC AAAGAAAAAA ATTCAGGTGA ATTCAAAACC TTCAATTCAG 
CCCAAGCCTT TATTGCTTCC AGCAGCACCC AAGACTCAAA CAAACTCCAG TGTTCCAGCA 
AAAACCATCA TTATTCAGAC AGTACCAACG CTTATGCCAT TGGCAAAGCA GCAACCAATT 
ATCAGTTTAC AACCTGCACC CACTAAAGGC CAGACGGTTT TGCTGTCTCA GCCTACTGTG 
GTACAACTTC AAGCACCTGG AGTTCTGCCC TCTGCTCAGC CAGTCCTTGC TGTTGCTGGG 
GGAGTCACAC AGCTCCCTAA TCACGTGGTG AATGTGGTAC CAGCCCCTTC AGCGAATAGC 
CCAGTGAATG GAAAACTTTC CGTGACTAAA CCTGTCCTAC AAAGTACCAT GAGAAATGTC 
GGTTCAGATA TTGCTGTGCT AAGGAGACAG CAACGTATGA TAAAAAATCG AGAATCCGCT 
TGTCAGTCTC GCAAGAAGAA GAAAGAATAT ATGCTAGGGT TAGAGGCGAG ATTAAAGGCT 
GCCCTCTCAG AAAACGAGCA ACTGAAGAAA GAAAATGGAA CACTGAAGCG GCAGCTGGAT 
GAAGTTGTGT CAGAGAACCA GAGGCTTAAA GTCCCTAGTC CAAAGCGAAG AGTTGTCTGT 
GTGATGATAG TATTGGCATT TATAATACTG AACTATGGAC CTATGAGCAT GTTGGAACAG 
GATTCCAGGA GAATGAACCC TAGTGTGAGC CCTGCAAATC AAAGGAGGCA CCTTCTAGGA 
TTTTCTGCTA AAGAGGCACA GGACACATCA GATGGTATTA TCCAGAAAAA CAGCTACAGA 
TATGATCATT CTGTTTCAAA TGACAAAGCC CTGATGGTGC TAACTGAAGA ACCATTGCTT 
TACATTCCTC CACCTCCTTG TCAGCCCCTA ATTAACACAA CAGAGTCTCT CAGGTTAAAT 
CATGAACTTC GAGGATGGGT TCATAGACAT GAAGTAGAAA GGACCAAGTC AAGAAGAATG 
ACAAATAATC AACAGAAAAC CCGTATTCTT CAGGGTGCTC TGGAACAGGG CTCAAATTCT 
CAGCTGATGG CTGTTCAATA CACAGAAACC ACTAGTAGTA TCAGGAACTC AGGGAGTGAG 
CTACAAGTGT ATTATGCTTC ACCCAGAAGT TATCAAGACT TTTTTGAAGC CATCCGCAGA 
AGGGGAGACA CATTTTATGT TGTGTCATTT CGAAGGGATC ACCTGCTGTT ACCAGCTACC 
ACCCATAACA AGACCACAAG ACCAAAAATG TCAATTGTGT TACCAGCAAT AAACATAAAT 
GAGAATGTGA TCAATGGGCA GGACTACGAA GTGATGATGC AGATTGACTG TCAGGTGATG 
GACACCAGGA TCCTCCATAT CAAAAGTTCG TCAGTTCCTC CTTACCTCCG AGATCAGCAG 
AGGAATCAAA CCAACACCTT CTTTGGCTCC CCTCCCGCAG CCACAGAGGC AACCCACGTT 
GTCAGCACCA TCCCTGAGTC ATTACAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATF6 ( XM_011509308.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011507610.1 Homo sapiens activating transcription factor 6 (ATF6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu65141
Clone ID Related Accession (Same CDS sequence)	XM_011509308.1
Accession Version	XM_011509308.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2070bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cyclic AMP-dependent transcription factor ATF-6 alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGGAGC CGGCTGGGGT TGCCGGCACC ATGGAGTCAC CTTTTAGCCC GGGACTCTTT 
CACAGGCTGG ATGAAGATTG GGATTCTGCT CTCTTTGCTG AACTCGGTTA TTTCACAGAC 
ACTGATGAGC TGCAATTGGA AGCAGCAAAT GAGACGTATG AAAACAATTT TGATAATCTT 
GATTTTGATT TGGATTTGAT GCCTTGGGAG TCAGACATTT GGGACATCAA CAACCAAATC 
TGTACAGTTA AAGATATTAA GGCAGAACCT CAGCCACTTT CTCCAGCCTC CTCAAGTTAT 
TCAGTCTCGT CTCCTCGGTC AGTGGACTCT TATTCTTCAA CTCAGCATGT TCCTGAGGAG 
TTGGATTTGT CTTCTAGTTC TCAGATGTCT CCCCTTTCCT TATATGGTGA AAACTCTAAT 
AGTCTCTCTT CAGCGGAGCC ACTGAAGGAA GATAAGCCTG TCACTGGTCC TAGGAACAAG 
ACTGAAAATG GACTGACTCC AAAGAAAAAA ATTCAGGTGA ATTCAAAACC TTCAATTCAG 
CCCAAGCCTT TATTGCTTCC AGCAGCACCC AAGACTCAAA CAAACTCCAG TGTTCCAGCA 
AAAACCATCA TTATTCAGAC AGTACCAACG CTTATGCCAT TGGCAAAGCA GCAACCAATT 
ATCAGTTTAC AACCTGCACC CACTAAAGGC CAGACGGTTT TGCTGTCTCA GCCTACTGTG 
GTACAACTTC AAGCACCTGG AGTTCTGCCC TCTGCTCAGC CAGTCCTTGC TGTTGCTGGG 
GGAGTCACAC AGCTCCCTAA TCACGTGGTG AATGTGGTAC CAGCCCCTTC AGCGAATAGC 
CCAGTGAATG GAAAACTTTC CGTGACTAAA CCTGTCCTAC AAAGTACCAT GAGAAATGTC 
GGTTCAGATA TTGCTGTGCT AAGGAGACAG CAACGTATGA TAAAAAATCG AGAATCCGCT 
TGTCAGTCTC GCAAGAAGAA GAAAGAATAT ATGCTAGGGT TAGAGGCGAG ATTAAAGGCT 
GCCCTCTCAG AAAACGAGCA ACTGAAGAAA GAAAATGGAA CACTGAAGCG GCAGCTGGAT 
GAAGTTGTGT CAGAGAACCA GAGGCTTAAA GTCCCTAGTC CAAAGCGAAG AGTTGTCTGT 
GTGATGATAG TATTGGCATT TATAATACTG AACTATGGAC CTATGAGCAT GTTGGAACAG 
GATTCCAGGA GAATGAACCC TAGTGTGAGC CCTGCAAATC AAAGGAGGCA CCTTCTAGGA 
TTTTCTGCTA AAGAGGCACA GGACACATCA GATGGTATTA TCCAGAAAAA CAGCTACAGC 
AAACTTCTTA GGAATTTAAG ATACAAGGAA ACAAATTTTG TGCATCCATG TTTCAGATAT 
GATCATTCTG TTTCAAATGA CAAAGCCCTG ATGGTGCTAA CTGAAGAACC ATTGCTTTAC 
ATTCCTCCAC CTCCTTGTCA GCCCCTAATT AACACAACAG AGTCTCTCAG GTTAAATCAT 
GAACTTCGAG GATGGGTTCA TAGACATGAA GTAGAAAGGA CCAAGTCAAG AAGAATGACA 
AATAATCAAC AGAAAACCCG TATTCTTCAG GGTGCTCTGG AACAGGGCTC AAATTCTCAG 
CTGATGGCTG TTCAATACAC AGAAACCACT AGTAGTATCA GCAGGAACTC AGGGAGTGAG 
CTACAAGTGT ATTATGCTTC ACCCAGAAGT TATCAAGACT TTTTTGAAGC CATCCGCAGA 
AGGGGAGACA CATTTTATGT TGTGTCATTT CGAAGGGATC ACCTGCTGTT ACCAGCTACC 
ACCCATAACA AGACCACAAG ACCAAAAATG TCAATTGTGT TACCAGCAAT AAACATAAAT 
GAGAATGTGA TCAATGGGCA GGACTACGAA GTGATGATGC AGATTGACTG TCAGGTGATG 
GACACCAGGA TCCTCCATAT CAAAAGTTCG TCAGTTCCTC CTTACCTCCG AGATCAGCAG 
AGGAATCAAA CCAACACCTT CTTTGGCTCC CCTCCCGCAG CCACAGAGGC AACCCACGTT 
GTCAGCACCA TCCCTGAGTC ATTACAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011507610.1
CDS	42..2111
Translation	MGEPAGVAGTMESPFSPGLFHRLDEDWDSALFAELGYFTDTDELQLEAANETYENNFDNLDFDLDLMPWESDIWDINNQICTVKDIKAEPQPLSPASSSYSVSSPRSVDSYSSTQHVPEELDLSSSSQMSPLSLYGENSNSLSSAEPLKEDKPVTGPRNKTENGLTPKKKIQVNSKPSIQPKPLLLPAAPKTQTNSSVPAKTIIIQTVPTLMPLAKQQPIISLQPAPTKGQTVLLSQPTVVQLQAPGVLPSAQPVLAVAGGVTQLPNHVVNVVPAPSANSPVNGKLSVTKPVLQSTMRNVGSDIAVLRRQQRMIKNRESACQSRKKKKEYMLGLEARLKAALSENEQLKKENGTLKRQLDEVVSENQRLKVPSPKRRVVCVMIVLAFIILNYGPMSMLEQDSRRMNPSVSPANQRRHLLGFSAKEAQDTSDGIIQKNSYSKLLRNLRYKETNFVHPCFRYDHSVSNDKALMVLTEEPLLYIPPPPCQPLINTTESLRLNHELRGWVHRHEVERTKSRRMTNNQQKTRILQGALEQGSNSQLMAVQYTETTSSISRNSGSELQVYYASPRSYQDFFEAIRRRGDTFYVVSFRRDHLLLPATTHNKTTRPKMSIVLPAININENVINGQDYEVMMQIDCQVMDTRILHIKSSSVPPYLRDQQRNQTNTFFGSPPAATEATHVVSTIPESLQ

Target ORF information:

RefSeq Version	XM_011509308.1
Organism	Homo sapiens(human)
Definition	Homo sapiens activating transcription factor 6 (ATF6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011509308.1

ORF Insert Sequence:

ATGGGGGAGC CGGCTGGGGT TGCCGGCACC ATGGAGTCAC CTTTTAGCCC GGGACTCTTT 
CACAGGCTGG ATGAAGATTG GGATTCTGCT CTCTTTGCTG AACTCGGTTA TTTCACAGAC 
ACTGATGAGC TGCAATTGGA AGCAGCAAAT GAGACGTATG AAAACAATTT TGATAATCTT 
GATTTTGATT TGGATTTGAT GCCTTGGGAG TCAGACATTT GGGACATCAA CAACCAAATC 
TGTACAGTTA AAGATATTAA GGCAGAACCT CAGCCACTTT CTCCAGCCTC CTCAAGTTAT 
TCAGTCTCGT CTCCTCGGTC AGTGGACTCT TATTCTTCAA CTCAGCATGT TCCTGAGGAG 
TTGGATTTGT CTTCTAGTTC TCAGATGTCT CCCCTTTCCT TATATGGTGA AAACTCTAAT 
AGTCTCTCTT CAGCGGAGCC ACTGAAGGAA GATAAGCCTG TCACTGGTCC TAGGAACAAG 
ACTGAAAATG GACTGACTCC AAAGAAAAAA ATTCAGGTGA ATTCAAAACC TTCAATTCAG 
CCCAAGCCTT TATTGCTTCC AGCAGCACCC AAGACTCAAA CAAACTCCAG TGTTCCAGCA 
AAAACCATCA TTATTCAGAC AGTACCAACG CTTATGCCAT TGGCAAAGCA GCAACCAATT 
ATCAGTTTAC AACCTGCACC CACTAAAGGC CAGACGGTTT TGCTGTCTCA GCCTACTGTG 
GTACAACTTC AAGCACCTGG AGTTCTGCCC TCTGCTCAGC CAGTCCTTGC TGTTGCTGGG 
GGAGTCACAC AGCTCCCTAA TCACGTGGTG AATGTGGTAC CAGCCCCTTC AGCGAATAGC 
CCAGTGAATG GAAAACTTTC CGTGACTAAA CCTGTCCTAC AAAGTACCAT GAGAAATGTC 
GGTTCAGATA TTGCTGTGCT AAGGAGACAG CAACGTATGA TAAAAAATCG AGAATCCGCT 
TGTCAGTCTC GCAAGAAGAA GAAAGAATAT ATGCTAGGGT TAGAGGCGAG ATTAAAGGCT 
GCCCTCTCAG AAAACGAGCA ACTGAAGAAA GAAAATGGAA CACTGAAGCG GCAGCTGGAT 
GAAGTTGTGT CAGAGAACCA GAGGCTTAAA GTCCCTAGTC CAAAGCGAAG AGTTGTCTGT 
GTGATGATAG TATTGGCATT TATAATACTG AACTATGGAC CTATGAGCAT GTTGGAACAG 
GATTCCAGGA GAATGAACCC TAGTGTGAGC CCTGCAAATC AAAGGAGGCA CCTTCTAGGA 
TTTTCTGCTA AAGAGGCACA GGACACATCA GATGGTATTA TCCAGAAAAA CAGCTACAGC 
AAACTTCTTA GGAATTTAAG ATACAAGGAA ACAAATTTTG TGCATCCATG TTTCAGATAT 
GATCATTCTG TTTCAAATGA CAAAGCCCTG ATGGTGCTAA CTGAAGAACC ATTGCTTTAC 
ATTCCTCCAC CTCCTTGTCA GCCCCTAATT AACACAACAG AGTCTCTCAG GTTAAATCAT 
GAACTTCGAG GATGGGTTCA TAGACATGAA GTAGAAAGGA CCAAGTCAAG AAGAATGACA 
AATAATCAAC AGAAAACCCG TATTCTTCAG GGTGCTCTGG AACAGGGCTC AAATTCTCAG 
CTGATGGCTG TTCAATACAC AGAAACCACT AGTAGTATCA GCAGGAACTC AGGGAGTGAG 
CTACAAGTGT ATTATGCTTC ACCCAGAAGT TATCAAGACT TTTTTGAAGC CATCCGCAGA 
AGGGGAGACA CATTTTATGT TGTGTCATTT CGAAGGGATC ACCTGCTGTT ACCAGCTACC 
ACCCATAACA AGACCACAAG ACCAAAAATG TCAATTGTGT TACCAGCAAT AAACATAAAT 
GAGAATGTGA TCAATGGGCA GGACTACGAA GTGATGATGC AGATTGACTG TCAGGTGATG 
GACACCAGGA TCCTCCATAT CAAAAGTTCG TCAGTTCCTC CTTACCTCCG AGATCAGCAG 
AGGAATCAAA CCAACACCTT CTTTGGCTCC CCTCCCGCAG CCACAGAGGC AACCCACGTT 
GTCAGCACCA TCCCTGAGTC ATTACAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATF6 ( XM_011509309.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011507611.1 Homo sapiens activating transcription factor 6 (ATF6), transcript variant X2, mRNA.

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CloneID	OHu65142
Clone ID Related Accession (Same CDS sequence)	XM_011509309.1
Accession Version	XM_011509309.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2067bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cyclic AMP-dependent transcription factor ATF-6 alpha isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGGAGC CGGCTGGGGT TGCCGGCACC ATGGAGTCAC CTTTTAGCCC GGGACTCTTT 
CACAGGCTGG ATGAAGATTG GGATTCTGCT CTCTTTGCTG AACTCGGTTA TTTCACAGAC 
ACTGATGAGC TGCAATTGGA AGCAGCAAAT GAGACGTATG AAAACAATTT TGATAATCTT 
GATTTTGATT TGGATTTGAT GCCTTGGGAG TCAGACATTT GGGACATCAA CAACCAAATC 
TGTACAGTTA AAGATATTAA GGCAGAACCT CAGCCACTTT CTCCAGCCTC CTCAAGTTAT 
TCAGTCTCGT CTCCTCGGTC AGTGGACTCT TATTCTTCAA CTCAGCATGT TCCTGAGGAG 
TTGGATTTGT CTTCTAGTTC TCAGATGTCT CCCCTTTCCT TATATGGTGA AAACTCTAAT 
AGTCTCTCTT CAGCGGAGCC ACTGAAGGAA GATAAGCCTG TCACTGGTCC TAGGAACAAG 
ACTGAAAATG GACTGACTCC AAAGAAAAAA ATTCAGGTGA ATTCAAAACC TTCAATTCAG 
CCCAAGCCTT TATTGCTTCC AGCAGCACCC AAGACTCAAA CAAACTCCAG TGTTCCAGCA 
AAAACCATCA TTATTCAGAC AGTACCAACG CTTATGCCAT TGGCAAAGCA GCAACCAATT 
ATCAGTTTAC AACCTGCACC CACTAAAGGC CAGACGGTTT TGCTGTCTCA GCCTACTGTG 
GTACAACTTC AAGCACCTGG AGTTCTGCCC TCTGCTCAGC CAGTCCTTGC TGTTGCTGGG 
GGAGTCACAC AGCTCCCTAA TCACGTGGTG AATGTGGTAC CAGCCCCTTC AGCGAATAGC 
CCAGTGAATG GAAAACTTTC CGTGACTAAA CCTGTCCTAC AAAGTACCAT GAGAAATGTC 
GGTTCAGATA TTGCTGTGCT AAGGAGACAG CAACGTATGA TAAAAAATCG AGAATCCGCT 
TGTCAGTCTC GCAAGAAGAA GAAAGAATAT ATGCTAGGGT TAGAGGCGAG ATTAAAGGCT 
GCCCTCTCAG AAAACGAGCA ACTGAAGAAA GAAAATGGAA CACTGAAGCG GCAGCTGGAT 
GAAGTTGTGT CAGAGAACCA GAGGCTTAAA GTCCCTAGTC CAAAGCGAAG AGTTGTCTGT 
GTGATGATAG TATTGGCATT TATAATACTG AACTATGGAC CTATGAGCAT GTTGGAACAG 
GATTCCAGGA GAATGAACCC TAGTGTGAGC CCTGCAAATC AAAGGAGGCA CCTTCTAGGA 
TTTTCTGCTA AAGAGGCACA GGACACATCA GATGGTATTA TCCAGAAAAA CAGCTACAGC 
AAACTTCTTA GGAATTTAAG ATACAAGGAA ACAAATTTTG TGCATCCATG TTTCAGATAT 
GATCATTCTG TTTCAAATGA CAAAGCCCTG ATGGTGCTAA CTGAAGAACC ATTGCTTTAC 
ATTCCTCCAC CTCCTTGTCA GCCCCTAATT AACACAACAG AGTCTCTCAG GTTAAATCAT 
GAACTTCGAG GATGGGTTCA TAGACATGAA GTAGAAAGGA CCAAGTCAAG AAGAATGACA 
AATAATCAAC AGAAAACCCG TATTCTTCAG GGTGCTCTGG AACAGGGCTC AAATTCTCAG 
CTGATGGCTG TTCAATACAC AGAAACCACT AGTAGTATCA GGAACTCAGG GAGTGAGCTA 
CAAGTGTATT ATGCTTCACC CAGAAGTTAT CAAGACTTTT TTGAAGCCAT CCGCAGAAGG 
GGAGACACAT TTTATGTTGT GTCATTTCGA AGGGATCACC TGCTGTTACC AGCTACCACC 
CATAACAAGA CCACAAGACC AAAAATGTCA ATTGTGTTAC CAGCAATAAA CATAAATGAG 
AATGTGATCA ATGGGCAGGA CTACGAAGTG ATGATGCAGA TTGACTGTCA GGTGATGGAC 
ACCAGGATCC TCCATATCAA AAGTTCGTCA GTTCCTCCTT ACCTCCGAGA TCAGCAGAGG 
AATCAAACCA ACACCTTCTT TGGCTCCCCT CCCGCAGCCA CAGAGGCAAC CCACGTTGTC 
AGCACCATCC CTGAGTCATT ACAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011507611.1
CDS	42..2108
Translation	MGEPAGVAGTMESPFSPGLFHRLDEDWDSALFAELGYFTDTDELQLEAANETYENNFDNLDFDLDLMPWESDIWDINNQICTVKDIKAEPQPLSPASSSYSVSSPRSVDSYSSTQHVPEELDLSSSSQMSPLSLYGENSNSLSSAEPLKEDKPVTGPRNKTENGLTPKKKIQVNSKPSIQPKPLLLPAAPKTQTNSSVPAKTIIIQTVPTLMPLAKQQPIISLQPAPTKGQTVLLSQPTVVQLQAPGVLPSAQPVLAVAGGVTQLPNHVVNVVPAPSANSPVNGKLSVTKPVLQSTMRNVGSDIAVLRRQQRMIKNRESACQSRKKKKEYMLGLEARLKAALSENEQLKKENGTLKRQLDEVVSENQRLKVPSPKRRVVCVMIVLAFIILNYGPMSMLEQDSRRMNPSVSPANQRRHLLGFSAKEAQDTSDGIIQKNSYSKLLRNLRYKETNFVHPCFRYDHSVSNDKALMVLTEEPLLYIPPPPCQPLINTTESLRLNHELRGWVHRHEVERTKSRRMTNNQQKTRILQGALEQGSNSQLMAVQYTETTSSIRNSGSELQVYYASPRSYQDFFEAIRRRGDTFYVVSFRRDHLLLPATTHNKTTRPKMSIVLPAININENVINGQDYEVMMQIDCQVMDTRILHIKSSSVPPYLRDQQRNQTNTFFGSPPAATEATHVVSTIPESLQ

Target ORF information:

RefSeq Version	XM_011509309.1
Organism	Homo sapiens(human)
Definition	Homo sapiens activating transcription factor 6 (ATF6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011509309.1

ORF Insert Sequence:

ATGGGGGAGC CGGCTGGGGT TGCCGGCACC ATGGAGTCAC CTTTTAGCCC GGGACTCTTT 
CACAGGCTGG ATGAAGATTG GGATTCTGCT CTCTTTGCTG AACTCGGTTA TTTCACAGAC 
ACTGATGAGC TGCAATTGGA AGCAGCAAAT GAGACGTATG AAAACAATTT TGATAATCTT 
GATTTTGATT TGGATTTGAT GCCTTGGGAG TCAGACATTT GGGACATCAA CAACCAAATC 
TGTACAGTTA AAGATATTAA GGCAGAACCT CAGCCACTTT CTCCAGCCTC CTCAAGTTAT 
TCAGTCTCGT CTCCTCGGTC AGTGGACTCT TATTCTTCAA CTCAGCATGT TCCTGAGGAG 
TTGGATTTGT CTTCTAGTTC TCAGATGTCT CCCCTTTCCT TATATGGTGA AAACTCTAAT 
AGTCTCTCTT CAGCGGAGCC ACTGAAGGAA GATAAGCCTG TCACTGGTCC TAGGAACAAG 
ACTGAAAATG GACTGACTCC AAAGAAAAAA ATTCAGGTGA ATTCAAAACC TTCAATTCAG 
CCCAAGCCTT TATTGCTTCC AGCAGCACCC AAGACTCAAA CAAACTCCAG TGTTCCAGCA 
AAAACCATCA TTATTCAGAC AGTACCAACG CTTATGCCAT TGGCAAAGCA GCAACCAATT 
ATCAGTTTAC AACCTGCACC CACTAAAGGC CAGACGGTTT TGCTGTCTCA GCCTACTGTG 
GTACAACTTC AAGCACCTGG AGTTCTGCCC TCTGCTCAGC CAGTCCTTGC TGTTGCTGGG 
GGAGTCACAC AGCTCCCTAA TCACGTGGTG AATGTGGTAC CAGCCCCTTC AGCGAATAGC 
CCAGTGAATG GAAAACTTTC CGTGACTAAA CCTGTCCTAC AAAGTACCAT GAGAAATGTC 
GGTTCAGATA TTGCTGTGCT AAGGAGACAG CAACGTATGA TAAAAAATCG AGAATCCGCT 
TGTCAGTCTC GCAAGAAGAA GAAAGAATAT ATGCTAGGGT TAGAGGCGAG ATTAAAGGCT 
GCCCTCTCAG AAAACGAGCA ACTGAAGAAA GAAAATGGAA CACTGAAGCG GCAGCTGGAT 
GAAGTTGTGT CAGAGAACCA GAGGCTTAAA GTCCCTAGTC CAAAGCGAAG AGTTGTCTGT 
GTGATGATAG TATTGGCATT TATAATACTG AACTATGGAC CTATGAGCAT GTTGGAACAG 
GATTCCAGGA GAATGAACCC TAGTGTGAGC CCTGCAAATC AAAGGAGGCA CCTTCTAGGA 
TTTTCTGCTA AAGAGGCACA GGACACATCA GATGGTATTA TCCAGAAAAA CAGCTACAGC 
AAACTTCTTA GGAATTTAAG ATACAAGGAA ACAAATTTTG TGCATCCATG TTTCAGATAT 
GATCATTCTG TTTCAAATGA CAAAGCCCTG ATGGTGCTAA CTGAAGAACC ATTGCTTTAC 
ATTCCTCCAC CTCCTTGTCA GCCCCTAATT AACACAACAG AGTCTCTCAG GTTAAATCAT 
GAACTTCGAG GATGGGTTCA TAGACATGAA GTAGAAAGGA CCAAGTCAAG AAGAATGACA 
AATAATCAAC AGAAAACCCG TATTCTTCAG GGTGCTCTGG AACAGGGCTC AAATTCTCAG 
CTGATGGCTG TTCAATACAC AGAAACCACT AGTAGTATCA GGAACTCAGG GAGTGAGCTA 
CAAGTGTATT ATGCTTCACC CAGAAGTTAT CAAGACTTTT TTGAAGCCAT CCGCAGAAGG 
GGAGACACAT TTTATGTTGT GTCATTTCGA AGGGATCACC TGCTGTTACC AGCTACCACC 
CATAACAAGA CCACAAGACC AAAAATGTCA ATTGTGTTAC CAGCAATAAA CATAAATGAG 
AATGTGATCA ATGGGCAGGA CTACGAAGTG ATGATGCAGA TTGACTGTCA GGTGATGGAC 
ACCAGGATCC TCCATATCAA AAGTTCGTCA GTTCCTCCTT ACCTCCGAGA TCAGCAGAGG 
AATCAAACCA ACACCTTCTT TGGCTCCCCT CCCGCAGCCA CAGAGGCAAC CCACGTTGTC 
AGCACCATCC CTGAGTCATT ACAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SUMOylation represses the transcriptional activity of the Unfolded Protein Response transducer ATF6.
Biochemical and biophysical research communications494(3-4)446-451(2017 12)
Hou X,Yang Z,Zhang K,Fang D,Sun F

Divest yourself of a preconceived idea: transcription factor ATF6 is not a soluble protein!
Molecular biology of the cell21(9)1435-8(2010 May)
Mori K

The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels.
Arteriosclerosis, thrombosis, and vascular biology29(9)1322-7(2009 Sep)
Meex SJ,Weissglas-Volkov D,van der Kallen CJ,Thuerauf DJ,van Greevenbroek MM,Schalkwijk CG,Stehouwer CD,Feskens EJ,Heldens L,Ayoubi TA,Hofker MH,Wouters BG,Vlietinck R,Sinsheimer JS,Taskinen MR,Kuusisto J,Laakso M,de Bruin TW,Pajukanta P,Glembotski CC

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ATF6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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