FKBP5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FKBP5
Entrez Gene ID	2289
Full Name	FK506 binding protein 5
Synonyms	AIG6,FKBP51,FKBP54,P54,PPIase,Ptg-10
General protein information	Preferred Names FK506 binding protein 5 Names peptidyl-prolyl cis-trans isomerase FKBP5 51 kDa FK506-binding protein 51 kDa FKBP 54 kDa progesterone receptor-associated immunophilin FF1 antigen FKBP-51 HSP90-binding immunophilin PPIase FKBP5 T-cell FK506-binding protein androgen-regulated protein 6 peptidylprolyl cis-trans isomerase rotamase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p21.31
Summary	The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009].
Disorder MIM:	602623
Disorder Html:	{Major depressive disorder and accelerated response to antidepressant drug treatment}, 608516 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_004117.3	NP_004108.1	peptidyl-prolyl cis-trans isomerase FKBP5 isoform 1
NM_001145775.2	NP_001139247.1	peptidyl-prolyl cis-trans isomerase FKBP5 isoform 1
NM_001145777.1	NP_001139249.1	peptidyl-prolyl cis-trans isomerase FKBP5 isoform 2
NM_001145776.1	NP_001139248.1	peptidyl-prolyl cis-trans isomerase FKBP5 isoform 1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Fkbp5	NP_034350.1
Bos taurus (cattle)	FKBP5	NP_001179791.1
Pan troglodytes (chimpanzee)	FKBP5	XP_001172420.1
Rattus norvegicus (Norway rat)	Fkbp5	NP_001012174.1
Gallus gallus (chicken)	FKBP5	NP_001005431.1
Homo sapiens (human)	FKBP5	NP_004108.1
Canis lupus familiaris (dog)	FKBP5	XP_538880.2
Danio rerio (zebrafish)	fkbp5	NP_998314.1

Gene Ontology

The following FKBP5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FKBP5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu14983	NM_001145777.1 Latest version!	Homo sapiens FKBP prolyl isomerase 5 (FKBP5), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu15280	NM_001145776.1 Latest version!	Homo sapiens FKBP prolyl isomerase 5 (FKBP5), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu15280	NM_004117.3 Latest version!	Homo sapiens FKBP prolyl isomerase 5 (FKBP5), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu15280	NM_001145775.2 Latest version!	Homo sapiens FKBP prolyl isomerase 5 (FKBP5), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FKBP5 ( NM_001145777.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001139249.1 Homo sapiens FKBP prolyl isomerase 5 (FKBP5), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu14983
Clone ID Related Accession (Same CDS sequence)	NM_001145777.1
Accession Version	NM_001145777.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 807bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	peptidyl-prolyl cis-trans isomerase FKBP5 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL590400.5, AB209893.1 and AL033519.42. Transcript Variant: This variant (4) has multiple differences in the coding region and 3' UTR compared to variant 1 which result in a frameshift. The resulting protein (isoform 2) is shorter and has a distinct C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB209893.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467147, SAMEA2467150 [ECO:0000348] ##Evidence-Data-END##

ATGACTACTG ATGAAGGTGC CAAGAACAAT GAAGAAAGCC CCACAGCCAC TGTTGCTGAG 
CAGGGAGAGG ATATTACCTC CAAAAAAGAC AGGGGAGTAT TAAAGATTGT CAAAAGAGTG 
GGGAATGGTG AGGAAACGCC GATGATTGGA GACAAAGTTT ATGTCCATTA CAAAGGAAAA 
TTGTCAAATG GAAAGAAGTT TGATTCCAGT CATGATAGAA ATGAACCATT TGTCTTTAGT 
CTTGGCAAAG GCCAAGTCAT CAAGGCATGG GACATTGGGG TGGCTACCAT GAAGAAAGGA 
GAGATATGCC ATTTACTGTG CAAACCAGAA TATGCATATG GCTCGGCTGG CAGTCTCCCT 
AAAATTCCCT CGAATGCAAC TCTCTTTTTT GAGATTGAGC TCCTTGATTT CAAAGGAGAG 
GATTTATTTG AAGATGGAGG CATTATCCGG AGAACCAAAC GGAAAGGAGA GGGATATTCA 
AATCCAAACG AAGGAGCAAC AGTAGAAATC CACCTGGAAG GCCGCTGTGG TGGAAGGATG 
TTTGACTGCA GAGATGTGGC ATTCACTGTG GGCGAAGGAG AAGACCACGA CATTCCAATT 
GGAATTGACA AAGCTCTGGA GAAAATGCAG CGGGAAGAAC AATGTATTTT ATATCTTGGA 
CCAAGGCCAA AGAATCCTGG GAGATGGATA CCAAAGAAAA ATTGGAGCAG GCTGCCATTG 
TCAAAGAGAA GGGAACCGTA TACTTCAAGG TGTGTGAGTC CCTATGCAAT CCTTTCCATC 
TCAAAGAATT TATTCAAGTG TTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001139249.1
CDS	159..965
Translation	MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRPKNPGRWIPKKNWSRLPLSKRREPYTSRCVSPYAILSISKNLFKCW

Target ORF information:

RefSeq Version	NM_001145777.1
Organism	Homo sapiens(human)
Definition	Homo sapiens FKBP prolyl isomerase 5 (FKBP5), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145777.1

ORF Insert Sequence:

ATGACTACTG ATGAAGGTGC CAAGAACAAT GAAGAAAGCC CCACAGCCAC TGTTGCTGAG 
CAGGGAGAGG ATATTACCTC CAAAAAAGAC AGGGGAGTAT TAAAGATTGT CAAAAGAGTG 
GGGAATGGTG AGGAAACGCC GATGATTGGA GACAAAGTTT ATGTCCATTA CAAAGGAAAA 
TTGTCAAATG GAAAGAAGTT TGATTCCAGT CATGATAGAA ATGAACCATT TGTCTTTAGT 
CTTGGCAAAG GCCAAGTCAT CAAGGCATGG GACATTGGGG TGGCTACCAT GAAGAAAGGA 
GAGATATGCC ATTTACTGTG CAAACCAGAA TATGCATATG GCTCGGCTGG CAGTCTCCCT 
AAAATTCCCT CGAATGCAAC TCTCTTTTTT GAGATTGAGC TCCTTGATTT CAAAGGAGAG 
GATTTATTTG AAGATGGAGG CATTATCCGG AGAACCAAAC GGAAAGGAGA GGGATATTCA 
AATCCAAACG AAGGAGCAAC AGTAGAAATC CACCTGGAAG GCCGCTGTGG TGGAAGGATG 
TTTGACTGCA GAGATGTGGC ATTCACTGTG GGCGAAGGAG AAGACCACGA CATTCCAATT 
GGAATTGACA AAGCTCTGGA GAAAATGCAG CGGGAAGAAC AATGTATTTT ATATCTTGGA 
CCAAGGCCAA AGAATCCTGG GAGATGGATA CCAAAGAAAA ATTGGAGCAG GCTGCCATTG 
TCAAAGAGAA GGGAACCGTA TACTTCAAGG TGTGTGAGTC CCTATGCAAT CCTTTCCATC 
TCAAAGAATT TATTCAAGTG TTGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FKBP5 ( NM_004117.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004108.1 Homo sapiens FKBP prolyl isomerase 5 (FKBP5), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu15280
Clone ID Related Accession (Same CDS sequence)	NM_004117.3 , NM_001145775.2 , NM_001145776.1
Accession Version	NM_004117.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1374bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	peptidyl-prolyl cis-trans isomerase FKBP5 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB066174.1, BC111050.1, U42031.1, AL033519.42 and AW182642.1. On Mar 11, 2009 this sequence version replaced NM_004117.2. Transcript Variant: This variant (1) represents the shortest transcript and encodes the longer isoform (1). Variants 1, 2 and 3 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.3062.1, SRR1660805.175909.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467147, SAMN04284274 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGACTACTG ATGAAGGTGC CAAGAACAAT GAAGAAAGCC CCACAGCCAC TGTTGCTGAG 
CAGGGAGAGG ATATTACCTC CAAAAAAGAC AGGGGAGTAT TAAAGATTGT CAAAAGAGTG 
GGGAATGGTG AGGAAACGCC GATGATTGGA GACAAAGTTT ATGTCCATTA CAAAGGAAAA 
TTGTCAAATG GAAAGAAGTT TGATTCCAGT CATGATAGAA ATGAACCATT TGTCTTTAGT 
CTTGGCAAAG GCCAAGTCAT CAAGGCATGG GACATTGGGG TGGCTACCAT GAAGAAAGGA 
GAGATATGCC ATTTACTGTG CAAACCAGAA TATGCATATG GCTCGGCTGG CAGTCTCCCT 
AAAATTCCCT CGAATGCAAC TCTCTTTTTT GAGATTGAGC TCCTTGATTT CAAAGGAGAG 
GATTTATTTG AAGATGGAGG CATTATCCGG AGAACCAAAC GGAAAGGAGA GGGATATTCA 
AATCCAAACG AAGGAGCAAC AGTAGAAATC CACCTGGAAG GCCGCTGTGG TGGAAGGATG 
TTTGACTGCA GAGATGTGGC ATTCACTGTG GGCGAAGGAG AAGACCACGA CATTCCAATT 
GGAATTGACA AAGCTCTGGA GAAAATGCAG CGGGAAGAAC AATGTATTTT ATATCTTGGA 
CCAAGATATG GTTTTGGAGA GGCAGGGAAG CCTAAATTTG GCATTGAACC TAATGCTGAG 
CTTATATATG AAGTTACACT TAAGAGCTTC GAAAAGGCCA AAGAATCCTG GGAGATGGAT 
ACCAAAGAAA AATTGGAGCA GGCTGCCATT GTCAAAGAGA AGGGAACCGT ATACTTCAAG 
GGAGGCAAAT ACATGCAGGC GGTGATTCAG TATGGGAAGA TAGTGTCCTG GTTAGAGATG 
GAATATGGTT TATCAGAAAA GGAATCGAAA GCTTCTGAAT CATTTCTCCT TGCTGCCTTT 
CTGAACCTGG CCATGTGCTA CCTGAAGCTT AGAGAATACA CCAAAGCTGT TGAATGCTGT 
GACAAGGCCC TTGGACTGGA CAGTGCCAAT GAGAAAGGCT TGTATAGGAG GGGTGAAGCC 
CAGCTGCTCA TGAACGAGTT TGAGTCAGCC AAGGGTGACT TTGAGAAAGT GCTGGAAGTA 
AACCCCCAGA ATAAGGCTGC AAGACTGCAG ATCTCCATGT GCCAGAAAAA GGCCAAGGAG 
CACAACGAGC GGGACCGCAG GATATACGCC AACATGTTCA AGAAGTTTGC AGAGCAGGAT 
GCCAAGGAAG AGGCCAATAA AGCAATGGGC AAGAAGACTT CAGAAGGGGT CACTAATGAA 
AAAGGAACAG ACAGTCAAGC AATGGAAGAA GAGAAACCTG AGGGCCACGT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004108.1
CDS	159..1532
Translation	MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV

Target ORF information:

RefSeq Version	NM_004117.3
Organism	Homo sapiens(human)
Definition	Homo sapiens FKBP prolyl isomerase 5 (FKBP5), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004117.3

ORF Insert Sequence:

ATGACTACTG ATGAAGGTGC CAAGAACAAT GAAGAAAGCC CCACAGCCAC TGTTGCTGAG 
CAGGGAGAGG ATATTACCTC CAAAAAAGAC AGGGGAGTAT TAAAGATTGT CAAAAGAGTG 
GGGAATGGTG AGGAAACGCC GATGATTGGA GACAAAGTTT ATGTCCATTA CAAAGGAAAA 
TTGTCAAATG GAAAGAAGTT TGATTCCAGT CATGATAGAA ATGAACCATT TGTCTTTAGT 
CTTGGCAAAG GCCAAGTCAT CAAGGCATGG GACATTGGGG TGGCTACCAT GAAGAAAGGA 
GAGATATGCC ATTTACTGTG CAAACCAGAA TATGCATATG GCTCGGCTGG CAGTCTCCCT 
AAAATTCCCT CGAATGCAAC TCTCTTTTTT GAGATTGAGC TCCTTGATTT CAAAGGAGAG 
GATTTATTTG AAGATGGAGG CATTATCCGG AGAACCAAAC GGAAAGGAGA GGGATATTCA 
AATCCAAACG AAGGAGCAAC AGTAGAAATC CACCTGGAAG GCCGCTGTGG TGGAAGGATG 
TTTGACTGCA GAGATGTGGC ATTCACTGTG GGCGAAGGAG AAGACCACGA CATTCCAATT 
GGAATTGACA AAGCTCTGGA GAAAATGCAG CGGGAAGAAC AATGTATTTT ATATCTTGGA 
CCAAGATATG GTTTTGGAGA GGCAGGGAAG CCTAAATTTG GCATTGAACC TAATGCTGAG 
CTTATATATG AAGTTACACT TAAGAGCTTC GAAAAGGCCA AAGAATCCTG GGAGATGGAT 
ACCAAAGAAA AATTGGAGCA GGCTGCCATT GTCAAAGAGA AGGGAACCGT ATACTTCAAG 
GGAGGCAAAT ACATGCAGGC GGTGATTCAG TATGGGAAGA TAGTGTCCTG GTTAGAGATG 
GAATATGGTT TATCAGAAAA GGAATCGAAA GCTTCTGAAT CATTTCTCCT TGCTGCCTTT 
CTGAACCTGG CCATGTGCTA CCTGAAGCTT AGAGAATACA CCAAAGCTGT TGAATGCTGT 
GACAAGGCCC TTGGACTGGA CAGTGCCAAT GAGAAAGGCT TGTATAGGAG GGGTGAAGCC 
CAGCTGCTCA TGAACGAGTT TGAGTCAGCC AAGGGTGACT TTGAGAAAGT GCTGGAAGTA 
AACCCCCAGA ATAAGGCTGC AAGACTGCAG ATCTCCATGT GCCAGAAAAA GGCCAAGGAG 
CACAACGAGC GGGACCGCAG GATATACGCC AACATGTTCA AGAAGTTTGC AGAGCAGGAT 
GCCAAGGAAG AGGCCAATAA AGCAATGGGC AAGAAGACTT CAGAAGGGGT CACTAATGAA 
AAAGGAACAG ACAGTCAAGC AATGGAAGAA GAGAAACCTG AGGGCCACGT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FKBP5 ( NM_001145775.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001139247.1 Homo sapiens FKBP prolyl isomerase 5 (FKBP5), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu15280
Clone ID Related Accession (Same CDS sequence)	NM_004117.3 , NM_001145775.2 , NM_001145776.1
Accession Version	NM_001145775.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1374bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	peptidyl-prolyl cis-trans isomerase FKBP5 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC042605.1, KF458140.1, AL033519.42 and AW182642.1. This sequence is a reference standard in the RefSeqGene project. On Jan 17, 2014 this sequence version replaced NM_001145775.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC042605.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467147, SAMN04284274 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACTACTG ATGAAGGTGC CAAGAACAAT GAAGAAAGCC CCACAGCCAC TGTTGCTGAG 
CAGGGAGAGG ATATTACCTC CAAAAAAGAC AGGGGAGTAT TAAAGATTGT CAAAAGAGTG 
GGGAATGGTG AGGAAACGCC GATGATTGGA GACAAAGTTT ATGTCCATTA CAAAGGAAAA 
TTGTCAAATG GAAAGAAGTT TGATTCCAGT CATGATAGAA ATGAACCATT TGTCTTTAGT 
CTTGGCAAAG GCCAAGTCAT CAAGGCATGG GACATTGGGG TGGCTACCAT GAAGAAAGGA 
GAGATATGCC ATTTACTGTG CAAACCAGAA TATGCATATG GCTCGGCTGG CAGTCTCCCT 
AAAATTCCCT CGAATGCAAC TCTCTTTTTT GAGATTGAGC TCCTTGATTT CAAAGGAGAG 
GATTTATTTG AAGATGGAGG CATTATCCGG AGAACCAAAC GGAAAGGAGA GGGATATTCA 
AATCCAAACG AAGGAGCAAC AGTAGAAATC CACCTGGAAG GCCGCTGTGG TGGAAGGATG 
TTTGACTGCA GAGATGTGGC ATTCACTGTG GGCGAAGGAG AAGACCACGA CATTCCAATT 
GGAATTGACA AAGCTCTGGA GAAAATGCAG CGGGAAGAAC AATGTATTTT ATATCTTGGA 
CCAAGATATG GTTTTGGAGA GGCAGGGAAG CCTAAATTTG GCATTGAACC TAATGCTGAG 
CTTATATATG AAGTTACACT TAAGAGCTTC GAAAAGGCCA AAGAATCCTG GGAGATGGAT 
ACCAAAGAAA AATTGGAGCA GGCTGCCATT GTCAAAGAGA AGGGAACCGT ATACTTCAAG 
GGAGGCAAAT ACATGCAGGC GGTGATTCAG TATGGGAAGA TAGTGTCCTG GTTAGAGATG 
GAATATGGTT TATCAGAAAA GGAATCGAAA GCTTCTGAAT CATTTCTCCT TGCTGCCTTT 
CTGAACCTGG CCATGTGCTA CCTGAAGCTT AGAGAATACA CCAAAGCTGT TGAATGCTGT 
GACAAGGCCC TTGGACTGGA CAGTGCCAAT GAGAAAGGCT TGTATAGGAG GGGTGAAGCC 
CAGCTGCTCA TGAACGAGTT TGAGTCAGCC AAGGGTGACT TTGAGAAAGT GCTGGAAGTA 
AACCCCCAGA ATAAGGCTGC AAGACTGCAG ATCTCCATGT GCCAGAAAAA GGCCAAGGAG 
CACAACGAGC GGGACCGCAG GATATACGCC AACATGTTCA AGAAGTTTGC AGAGCAGGAT 
GCCAAGGAAG AGGCCAATAA AGCAATGGGC AAGAAGACTT CAGAAGGGGT CACTAATGAA 
AAAGGAACAG ACAGTCAAGC AATGGAAGAA GAGAAACCTG AGGGCCACGT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001139247.1
CDS	317..1690
Translation	MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV

Target ORF information:

RefSeq Version	NM_001145775.2
Organism	Homo sapiens(human)
Definition	Homo sapiens FKBP prolyl isomerase 5 (FKBP5), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145775.2

ORF Insert Sequence:

ATGACTACTG ATGAAGGTGC CAAGAACAAT GAAGAAAGCC CCACAGCCAC TGTTGCTGAG 
CAGGGAGAGG ATATTACCTC CAAAAAAGAC AGGGGAGTAT TAAAGATTGT CAAAAGAGTG 
GGGAATGGTG AGGAAACGCC GATGATTGGA GACAAAGTTT ATGTCCATTA CAAAGGAAAA 
TTGTCAAATG GAAAGAAGTT TGATTCCAGT CATGATAGAA ATGAACCATT TGTCTTTAGT 
CTTGGCAAAG GCCAAGTCAT CAAGGCATGG GACATTGGGG TGGCTACCAT GAAGAAAGGA 
GAGATATGCC ATTTACTGTG CAAACCAGAA TATGCATATG GCTCGGCTGG CAGTCTCCCT 
AAAATTCCCT CGAATGCAAC TCTCTTTTTT GAGATTGAGC TCCTTGATTT CAAAGGAGAG 
GATTTATTTG AAGATGGAGG CATTATCCGG AGAACCAAAC GGAAAGGAGA GGGATATTCA 
AATCCAAACG AAGGAGCAAC AGTAGAAATC CACCTGGAAG GCCGCTGTGG TGGAAGGATG 
TTTGACTGCA GAGATGTGGC ATTCACTGTG GGCGAAGGAG AAGACCACGA CATTCCAATT 
GGAATTGACA AAGCTCTGGA GAAAATGCAG CGGGAAGAAC AATGTATTTT ATATCTTGGA 
CCAAGATATG GTTTTGGAGA GGCAGGGAAG CCTAAATTTG GCATTGAACC TAATGCTGAG 
CTTATATATG AAGTTACACT TAAGAGCTTC GAAAAGGCCA AAGAATCCTG GGAGATGGAT 
ACCAAAGAAA AATTGGAGCA GGCTGCCATT GTCAAAGAGA AGGGAACCGT ATACTTCAAG 
GGAGGCAAAT ACATGCAGGC GGTGATTCAG TATGGGAAGA TAGTGTCCTG GTTAGAGATG 
GAATATGGTT TATCAGAAAA GGAATCGAAA GCTTCTGAAT CATTTCTCCT TGCTGCCTTT 
CTGAACCTGG CCATGTGCTA CCTGAAGCTT AGAGAATACA CCAAAGCTGT TGAATGCTGT 
GACAAGGCCC TTGGACTGGA CAGTGCCAAT GAGAAAGGCT TGTATAGGAG GGGTGAAGCC 
CAGCTGCTCA TGAACGAGTT TGAGTCAGCC AAGGGTGACT TTGAGAAAGT GCTGGAAGTA 
AACCCCCAGA ATAAGGCTGC AAGACTGCAG ATCTCCATGT GCCAGAAAAA GGCCAAGGAG 
CACAACGAGC GGGACCGCAG GATATACGCC AACATGTTCA AGAAGTTTGC AGAGCAGGAT 
GCCAAGGAAG AGGCCAATAA AGCAATGGGC AAGAAGACTT CAGAAGGGGT CACTAATGAA 
AAAGGAACAG ACAGTCAAGC AATGGAAGAA GAGAAACCTG AGGGCCACGT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FKBP5 ( NM_001145776.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001139248.1 Homo sapiens FKBP prolyl isomerase 5 (FKBP5), transcript variant 3, mRNA.

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CloneID	OHu15280
Clone ID Related Accession (Same CDS sequence)	NM_004117.3 , NM_001145775.2 , NM_001145776.1
Accession Version	NM_001145776.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1374bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	peptidyl-prolyl cis-trans isomerase FKBP5 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK312422.1, AL590400.5, AL033519.42 and AW182642.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK312422.1, SRR1803614.117113.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04284274 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACTACTG ATGAAGGTGC CAAGAACAAT GAAGAAAGCC CCACAGCCAC TGTTGCTGAG 
CAGGGAGAGG ATATTACCTC CAAAAAAGAC AGGGGAGTAT TAAAGATTGT CAAAAGAGTG 
GGGAATGGTG AGGAAACGCC GATGATTGGA GACAAAGTTT ATGTCCATTA CAAAGGAAAA 
TTGTCAAATG GAAAGAAGTT TGATTCCAGT CATGATAGAA ATGAACCATT TGTCTTTAGT 
CTTGGCAAAG GCCAAGTCAT CAAGGCATGG GACATTGGGG TGGCTACCAT GAAGAAAGGA 
GAGATATGCC ATTTACTGTG CAAACCAGAA TATGCATATG GCTCGGCTGG CAGTCTCCCT 
AAAATTCCCT CGAATGCAAC TCTCTTTTTT GAGATTGAGC TCCTTGATTT CAAAGGAGAG 
GATTTATTTG AAGATGGAGG CATTATCCGG AGAACCAAAC GGAAAGGAGA GGGATATTCA 
AATCCAAACG AAGGAGCAAC AGTAGAAATC CACCTGGAAG GCCGCTGTGG TGGAAGGATG 
TTTGACTGCA GAGATGTGGC ATTCACTGTG GGCGAAGGAG AAGACCACGA CATTCCAATT 
GGAATTGACA AAGCTCTGGA GAAAATGCAG CGGGAAGAAC AATGTATTTT ATATCTTGGA 
CCAAGATATG GTTTTGGAGA GGCAGGGAAG CCTAAATTTG GCATTGAACC TAATGCTGAG 
CTTATATATG AAGTTACACT TAAGAGCTTC GAAAAGGCCA AAGAATCCTG GGAGATGGAT 
ACCAAAGAAA AATTGGAGCA GGCTGCCATT GTCAAAGAGA AGGGAACCGT ATACTTCAAG 
GGAGGCAAAT ACATGCAGGC GGTGATTCAG TATGGGAAGA TAGTGTCCTG GTTAGAGATG 
GAATATGGTT TATCAGAAAA GGAATCGAAA GCTTCTGAAT CATTTCTCCT TGCTGCCTTT 
CTGAACCTGG CCATGTGCTA CCTGAAGCTT AGAGAATACA CCAAAGCTGT TGAATGCTGT 
GACAAGGCCC TTGGACTGGA CAGTGCCAAT GAGAAAGGCT TGTATAGGAG GGGTGAAGCC 
CAGCTGCTCA TGAACGAGTT TGAGTCAGCC AAGGGTGACT TTGAGAAAGT GCTGGAAGTA 
AACCCCCAGA ATAAGGCTGC AAGACTGCAG ATCTCCATGT GCCAGAAAAA GGCCAAGGAG 
CACAACGAGC GGGACCGCAG GATATACGCC AACATGTTCA AGAAGTTTGC AGAGCAGGAT 
GCCAAGGAAG AGGCCAATAA AGCAATGGGC AAGAAGACTT CAGAAGGGGT CACTAATGAA 
AAAGGAACAG ACAGTCAAGC AATGGAAGAA GAGAAACCTG AGGGCCACGT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001139248.1
CDS	204..1577
Translation	MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV

Target ORF information:

RefSeq Version	NM_001145776.1
Organism	Homo sapiens(human)
Definition	Homo sapiens FKBP prolyl isomerase 5 (FKBP5), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145776.1

ORF Insert Sequence:

ATGACTACTG ATGAAGGTGC CAAGAACAAT GAAGAAAGCC CCACAGCCAC TGTTGCTGAG 
CAGGGAGAGG ATATTACCTC CAAAAAAGAC AGGGGAGTAT TAAAGATTGT CAAAAGAGTG 
GGGAATGGTG AGGAAACGCC GATGATTGGA GACAAAGTTT ATGTCCATTA CAAAGGAAAA 
TTGTCAAATG GAAAGAAGTT TGATTCCAGT CATGATAGAA ATGAACCATT TGTCTTTAGT 
CTTGGCAAAG GCCAAGTCAT CAAGGCATGG GACATTGGGG TGGCTACCAT GAAGAAAGGA 
GAGATATGCC ATTTACTGTG CAAACCAGAA TATGCATATG GCTCGGCTGG CAGTCTCCCT 
AAAATTCCCT CGAATGCAAC TCTCTTTTTT GAGATTGAGC TCCTTGATTT CAAAGGAGAG 
GATTTATTTG AAGATGGAGG CATTATCCGG AGAACCAAAC GGAAAGGAGA GGGATATTCA 
AATCCAAACG AAGGAGCAAC AGTAGAAATC CACCTGGAAG GCCGCTGTGG TGGAAGGATG 
TTTGACTGCA GAGATGTGGC ATTCACTGTG GGCGAAGGAG AAGACCACGA CATTCCAATT 
GGAATTGACA AAGCTCTGGA GAAAATGCAG CGGGAAGAAC AATGTATTTT ATATCTTGGA 
CCAAGATATG GTTTTGGAGA GGCAGGGAAG CCTAAATTTG GCATTGAACC TAATGCTGAG 
CTTATATATG AAGTTACACT TAAGAGCTTC GAAAAGGCCA AAGAATCCTG GGAGATGGAT 
ACCAAAGAAA AATTGGAGCA GGCTGCCATT GTCAAAGAGA AGGGAACCGT ATACTTCAAG 
GGAGGCAAAT ACATGCAGGC GGTGATTCAG TATGGGAAGA TAGTGTCCTG GTTAGAGATG 
GAATATGGTT TATCAGAAAA GGAATCGAAA GCTTCTGAAT CATTTCTCCT TGCTGCCTTT 
CTGAACCTGG CCATGTGCTA CCTGAAGCTT AGAGAATACA CCAAAGCTGT TGAATGCTGT 
GACAAGGCCC TTGGACTGGA CAGTGCCAAT GAGAAAGGCT TGTATAGGAG GGGTGAAGCC 
CAGCTGCTCA TGAACGAGTT TGAGTCAGCC AAGGGTGACT TTGAGAAAGT GCTGGAAGTA 
AACCCCCAGA ATAAGGCTGC AAGACTGCAG ATCTCCATGT GCCAGAAAAA GGCCAAGGAG 
CACAACGAGC GGGACCGCAG GATATACGCC AACATGTTCA AGAAGTTTGC AGAGCAGGAT 
GCCAAGGAAG AGGCCAATAA AGCAATGGGC AAGAAGACTT CAGAAGGGGT CACTAATGAA 
AAAGGAACAG ACAGTCAAGC AATGGAAGAA GAGAAACCTG AGGGCCACGT ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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03-6811-6572

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FKBP5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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