Gene Symbol | MORC2 |
Entrez Gene ID | 22880 |
Full Name | MORC family CW-type zinc finger 2 |
Synonyms | CMT2Z,ZCW3,ZCWCC1 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription. The protein has been found to regulate the activity of ATP citrate lyase via specific interaction with this enzyme in the cytosol of lipogenic breast cancer cells. The protein also plays a role in lipogenesis and adipocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]. |
Disorder MIM: | |
Disorder Html: | Charcot-Marie-Tooth disease, axonal, type 2Z, 616688 (3) |