FGF3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FGF3
Entrez Gene ID	2248
Full Name	fibroblast growth factor 3
Synonyms	HBGF-3,INT2
General protein information	Preferred Names fibroblast growth factor 3 Names fibroblast growth factor 3 FGF-3 INT-2 proto-oncogene protein V-INT2 murine mammary tumor virus integration site oncogene homolog fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog) heparin-binding growth factor 3 murine mammary tumor virus integration site 2, mouse oncogene INT2 proto-oncogene Int-2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q13.3
Summary	The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation. [provided by RefSeq, Jul 2008].
Disorder MIM:	164950
Disorder Html:	Deafness, congenital with inner ear agenesis, microtia, and microdontia, 610706 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_005247.4	NP_005238.1	fibroblast growth factor 3 precursor
NM_005247.2	NP_005238.1	fibroblast growth factor 3 precursor
NM_005247.3	NP_005238.1	fibroblast growth factor 3 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	FGF3	NP_005238.1
	FGF3	XP_001100658.1
Rattus norvegicus (Norway rat)	Fgf3	NP_570830.1
Xenopus tropicalis (tropical clawed frog)	fgf3	NP_001008154.1
Bos taurus (cattle)	FGF3	XP_002699485.1
Mus musculus (house mouse)	Fgf3	NP_032033.2
Pan troglodytes (chimpanzee)	FGF3	XP_522092.2
Gallus gallus (chicken)	FGF3	NP_990658.1
Danio rerio (zebrafish)	fgf3	NP_571366.1

Gene Ontology
Bibliography

Related articles in PubMed

Inhibitory effects of int-2 gene on the invasion and metastasis of oral cancer cells.
Liu LM
European review for medical and pharmacological sciences21(24)5677-5682(2017 Dec)

HER2-Overexpressing Breast Cancers Amplify FGFR Signaling upon Acquisition of Resistance to Dual Therapeutic Blockade of HER2.
Hanker AB, Garrett JT, Estrada MV, Moore PD, Ericsson PG, Koch JP, Langley E, Singh S, Kim PS, Frampton GM, Sanford E, Owens P, Becker J, Groseclose MR, Castellino S, Joensuu H, Huober J, Brase JC, Majjaj S, Broh?e S, Venet D, Brown D, Baselga J, Piccart M, Sotiriou C, Arteaga CL
Clinical cancer research : an official journal of the American Association for Cancer Research23(15)4323-4334(2017 Aug)

Genetically confirmed thanatophoric dysplasia with fibroblast growth factor receptor 3 mutation.
Jung M, Park SH
Experimental and molecular pathology102(2)290-295(2017 04)

Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling.
Lamb R, Bonuccelli G, Ozsv?ri B, Peiris-Pag?s M, Fiorillo M, Smith DL, Bevilacqua G, Mazzanti CM, McDonnell LA, Naccarato AG, Chiu M, Wynne L, Martinez-Outschoorn UE, Sotgia F, Lisanti MP
Oncotarget6(31)30453-71(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

fibroblast growth factor receptor 3 missense mutations were identified in 5 cases of thanatophoric dysplasia
Title: Genetically confirmed thanatophoric dysplasia with fibroblast growth factor receptor 3 mutation.

MCF7 cells over-expressing both WNT1 and FGF3 show a 3.5-fold increase in mammosphere formation; conditioned media from these cells also promotes stem cell activity in untransfected parental MCF7 and T47D cells, as WNT1 and FGF3 are secreted factors.
Title: Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling.

FGF3 gene expression is altered in a human breast cancer progression model.
Title: Allelic loss at chromosome 11q13 alters FGF3 gene expression in a human breast cancer progression model.

analysis provided evidence for gene-gene interaction between FGF3 (rs4980700) and PAX9 (rs2073242), increasing risk for isolated oral clefts (p = 0.0003). FGF3 is associated with oral clefts and may interact with PAX9.
Title: Studies of genes involved in craniofacial development and tumorigenesis: FGF3 contributes to isolated oral clefts and may interact with PAX9.

Higher FGF-23 concentration was associated with LVED mass and with incident atrial fibrillation and may, in part, explain the link between chronic kidney disease and AF.
Title: Fibroblast growth factor-23 and incident atrial fibrillation: the Multi-Ethnic Study of Atherosclerosis (MESA) and the Cardiovascular Health Study (CHS).

The following FGF3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FGF3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18680	NM_005247.4 Latest version!	Homo sapiens fibroblast growth factor 3 (FGF3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
View Old Accession Versions >>
OHu18680	NM_005247.2	Homo sapiens fibroblast growth factor 3 (FGF3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
OHu18680	NM_005247.3	Homo sapiens fibroblast growth factor 3 (FGF3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FGF3 ( NM_005247.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005238.1 Homo sapiens fibroblast growth factor 3 (FGF3), mRNA.

Price & Availability↑

CloneID	OHu18680
Clone ID Related Accession (Same CDS sequence)	NM_005247.4 , NM_005247.2 , NM_005247.3
Accession Version	NM_005247.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	fibroblast growth factor 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP006345.4 and BC113739.1. This sequence is a reference standard in the RefSeqGene project. On May 7, 2019 this sequence version replaced NM_005247.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC113739.1, SRR3476690.433211.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000334134.4/ ENSP00000334122.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGCCTAA TCTGGCTGCT ACTGCTCAGC CTGCTGGAGC CCGGCTGGCC CGCAGCGGGC 
CCTGGGGCGC GGTTGCGGCG CGATGCGGGC GGCCGTGGCG GCGTCTACGA GCACCTTGGC 
GGGGCGCCCC GGCGCCGCAA GCTCTACTGC GCCACGAAGT ACCACCTCCA GCTGCACCCG 
AGCGGCCGCG TCAACGGCAG CCTGGAGAAC AGCGCCTACA GTATTTTGGA GATAACGGCA 
GTGGAGGTGG GCATTGTGGC CATCAGGGGT CTCTTCTCCG GGCGGTACCT GGCCATGAAC 
AAGAGGGGAC GACTCTATGC TTCGGAGCAC TACAGCGCCG AGTGCGAGTT TGTGGAGCGG 
ATCCACGAGC TGGGCTATAA TACGTATGCC TCCCGGCTGT ACCGGACGGT GTCTAGTACG 
CCTGGGGCCC GCCGGCAGCC CAGCGCCGAG AGACTGTGGT ACGTGTCTGT GAACGGCAAG 
GGCCGGCCCC GCAGGGGCTT CAAGACCCGC CGCACACAGA AGTCCTCCCT GTTCCTGCCC 
CGCGTGCTGG ACCACAGGGA CCACGAGATG GTGCGGCAGC TACAGAGTGG GCTGCCCAGA 
CCCCCTGGTA AGGGGGTCCA GCCCCGACGG CGGCGGCAGA AGCAGAGCCC GGATAACCTG 
GAGCCCTCTC ACGTTCAGGC TTCGAGACTG GGCTCCCAGC TGGAGGCCAG TGCGCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005238.1
CDS	484..1203
Translation	MGLIWLLLLSLLEPGWPAAGPGARLRRDAGGRGGVYEHLGGAPRRRKLYCATKYHLQLHPSGRVNGSLENSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHYSAECEFVERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRRGFKTRRTQKSSLFLPRVLDHRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPDNLEPSHVQASRLGSQLEASAH

Target ORF information:

RefSeq Version	NM_005247.4
Organism	Homo sapiens(human)
Definition	Homo sapiens fibroblast growth factor 3 (FGF3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005247.4

ORF Insert Sequence:

ATGGGCCTAA TCTGGCTGCT ACTGCTCAGC CTGCTGGAGC CCGGCTGGCC CGCAGCGGGC 
CCTGGGGCGC GGTTGCGGCG CGATGCGGGC GGCCGTGGCG GCGTCTACGA GCACCTTGGC 
GGGGCGCCCC GGCGCCGCAA GCTCTACTGC GCCACGAAGT ACCACCTCCA GCTGCACCCG 
AGCGGCCGCG TCAACGGCAG CCTGGAGAAC AGCGCCTACA GTATTTTGGA GATAACGGCA 
GTGGAGGTGG GCATTGTGGC CATCAGGGGT CTCTTCTCCG GGCGGTACCT GGCCATGAAC 
AAGAGGGGAC GACTCTATGC TTCGGAGCAC TACAGCGCCG AGTGCGAGTT TGTGGAGCGG 
ATCCACGAGC TGGGCTATAA TACGTATGCC TCCCGGCTGT ACCGGACGGT GTCTAGTACG 
CCTGGGGCCC GCCGGCAGCC CAGCGCCGAG AGACTGTGGT ACGTGTCTGT GAACGGCAAG 
GGCCGGCCCC GCAGGGGCTT CAAGACCCGC CGCACACAGA AGTCCTCCCT GTTCCTGCCC 
CGCGTGCTGG ACCACAGGGA CCACGAGATG GTGCGGCAGC TACAGAGTGG GCTGCCCAGA 
CCCCCTGGTA AGGGGGTCCA GCCCCGACGG CGGCGGCAGA AGCAGAGCCC GGATAACCTG 
GAGCCCTCTC ACGTTCAGGC TTCGAGACTG GGCTCCCAGC TGGAGGCCAG TGCGCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FGF3 ( NM_005247.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_005238.1 Homo sapiens fibroblast growth factor 3 (FGF3), mRNA.

Price & Availability↑

CloneID	OHu18680
Clone ID Related Accession (Same CDS sequence)	NM_005247.4 , NM_005247.2 , NM_005247.3
Accession Version	NM_005247.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	fibroblast growth factor 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from X14445.1. This sequence is a reference standard in the RefSeqGene project. On Sep 6, 2001 this sequence version replaced NM_005247.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC113739.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03465403 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCCTAA TCTGGCTGCT ACTGCTCAGC CTGCTGGAGC CCGGCTGGCC CGCAGCGGGC 
CCTGGGGCGC GGTTGCGGCG CGATGCGGGC GGCCGTGGCG GCGTCTACGA GCACCTTGGC 
GGGGCGCCCC GGCGCCGCAA GCTCTACTGC GCCACGAAGT ACCACCTCCA GCTGCACCCG 
AGCGGCCGCG TCAACGGCAG CCTGGAGAAC AGCGCCTACA GTATTTTGGA GATAACGGCA 
GTGGAGGTGG GCATTGTGGC CATCAGGGGT CTCTTCTCCG GGCGGTACCT GGCCATGAAC 
AAGAGGGGAC GACTCTATGC TTCGGAGCAC TACAGCGCCG AGTGCGAGTT TGTGGAGCGG 
ATCCACGAGC TGGGCTATAA TACGTATGCC TCCCGGCTGT ACCGGACGGT GTCTAGTACG 
CCTGGGGCCC GCCGGCAGCC CAGCGCCGAG AGACTGTGGT ACGTGTCTGT GAACGGCAAG 
GGCCGGCCCC GCAGGGGCTT CAAGACCCGC CGCACACAGA AGTCCTCCCT GTTCCTGCCC 
CGCGTGCTGG ACCACAGGGA CCACGAGATG GTGCGGCAGC TACAGAGTGG GCTGCCCAGA 
CCCCCTGGTA AGGGGGTCCA GCCCCGACGG CGGCGGCAGA AGCAGAGCCC GGATAACCTG 
GAGCCCTCTC ACGTTCAGGC TTCGAGACTG GGCTCCCAGC TGGAGGCCAG TGCGCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005238.1
CDS	492..1211
Translation	MGLIWLLLLSLLEPGWPAAGPGARLRRDAGGRGGVYEHLGGAPRRRKLYCATKYHLQLHPSGRVNGSLENSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHYSAECEFVERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRRGFKTRRTQKSSLFLPRVLDHRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPDNLEPSHVQASRLGSQLEASAH

Target ORF information:

RefSeq Version	NM_005247.2
Organism	Homo sapiens(human)
Definition	Homo sapiens fibroblast growth factor 3 (FGF3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005247.2

ORF Insert Sequence:

ATGGGCCTAA TCTGGCTGCT ACTGCTCAGC CTGCTGGAGC CCGGCTGGCC CGCAGCGGGC 
CCTGGGGCGC GGTTGCGGCG CGATGCGGGC GGCCGTGGCG GCGTCTACGA GCACCTTGGC 
GGGGCGCCCC GGCGCCGCAA GCTCTACTGC GCCACGAAGT ACCACCTCCA GCTGCACCCG 
AGCGGCCGCG TCAACGGCAG CCTGGAGAAC AGCGCCTACA GTATTTTGGA GATAACGGCA 
GTGGAGGTGG GCATTGTGGC CATCAGGGGT CTCTTCTCCG GGCGGTACCT GGCCATGAAC 
AAGAGGGGAC GACTCTATGC TTCGGAGCAC TACAGCGCCG AGTGCGAGTT TGTGGAGCGG 
ATCCACGAGC TGGGCTATAA TACGTATGCC TCCCGGCTGT ACCGGACGGT GTCTAGTACG 
CCTGGGGCCC GCCGGCAGCC CAGCGCCGAG AGACTGTGGT ACGTGTCTGT GAACGGCAAG 
GGCCGGCCCC GCAGGGGCTT CAAGACCCGC CGCACACAGA AGTCCTCCCT GTTCCTGCCC 
CGCGTGCTGG ACCACAGGGA CCACGAGATG GTGCGGCAGC TACAGAGTGG GCTGCCCAGA 
CCCCCTGGTA AGGGGGTCCA GCCCCGACGG CGGCGGCAGA AGCAGAGCCC GGATAACCTG 
GAGCCCTCTC ACGTTCAGGC TTCGAGACTG GGCTCCCAGC TGGAGGCCAG TGCGCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FGF3 ( NM_005247.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005238.1 Homo sapiens fibroblast growth factor 3 (FGF3), mRNA.

Price & Availability↑

CloneID	OHu18680
Clone ID Related Accession (Same CDS sequence)	NM_005247.4 , NM_005247.2 , NM_005247.3
Accession Version	NM_005247.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-27
Organism	Homo sapiens(human)
Product	fibroblast growth factor 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP006345.4 and BC113739.1. This sequence is a reference standard in the RefSeqGene project. On Oct 30, 2018 this sequence version replaced NM_005247.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.433211.1, BC113739.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCCTAA TCTGGCTGCT ACTGCTCAGC CTGCTGGAGC CCGGCTGGCC CGCAGCGGGC 
CCTGGGGCGC GGTTGCGGCG CGATGCGGGC GGCCGTGGCG GCGTCTACGA GCACCTTGGC 
GGGGCGCCCC GGCGCCGCAA GCTCTACTGC GCCACGAAGT ACCACCTCCA GCTGCACCCG 
AGCGGCCGCG TCAACGGCAG CCTGGAGAAC AGCGCCTACA GTATTTTGGA GATAACGGCA 
GTGGAGGTGG GCATTGTGGC CATCAGGGGT CTCTTCTCCG GGCGGTACCT GGCCATGAAC 
AAGAGGGGAC GACTCTATGC TTCGGAGCAC TACAGCGCCG AGTGCGAGTT TGTGGAGCGG 
ATCCACGAGC TGGGCTATAA TACGTATGCC TCCCGGCTGT ACCGGACGGT GTCTAGTACG 
CCTGGGGCCC GCCGGCAGCC CAGCGCCGAG AGACTGTGGT ACGTGTCTGT GAACGGCAAG 
GGCCGGCCCC GCAGGGGCTT CAAGACCCGC CGCACACAGA AGTCCTCCCT GTTCCTGCCC 
CGCGTGCTGG ACCACAGGGA CCACGAGATG GTGCGGCAGC TACAGAGTGG GCTGCCCAGA 
CCCCCTGGTA AGGGGGTCCA GCCCCGACGG CGGCGGCAGA AGCAGAGCCC GGATAACCTG 
GAGCCCTCTC ACGTTCAGGC TTCGAGACTG GGCTCCCAGC TGGAGGCCAG TGCGCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005238.1
CDS	289..1008
Translation	MGLIWLLLLSLLEPGWPAAGPGARLRRDAGGRGGVYEHLGGAPRRRKLYCATKYHLQLHPSGRVNGSLENSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHYSAECEFVERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRRGFKTRRTQKSSLFLPRVLDHRDHEMVRQLQSGLPRPPGKGVQPRRRRQKQSPDNLEPSHVQASRLGSQLEASAH

Target ORF information:

RefSeq Version	NM_005247.3
Organism	Homo sapiens(human)
Definition	Homo sapiens fibroblast growth factor 3 (FGF3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005247.3

ORF Insert Sequence:

ATGGGCCTAA TCTGGCTGCT ACTGCTCAGC CTGCTGGAGC CCGGCTGGCC CGCAGCGGGC 
CCTGGGGCGC GGTTGCGGCG CGATGCGGGC GGCCGTGGCG GCGTCTACGA GCACCTTGGC 
GGGGCGCCCC GGCGCCGCAA GCTCTACTGC GCCACGAAGT ACCACCTCCA GCTGCACCCG 
AGCGGCCGCG TCAACGGCAG CCTGGAGAAC AGCGCCTACA GTATTTTGGA GATAACGGCA 
GTGGAGGTGG GCATTGTGGC CATCAGGGGT CTCTTCTCCG GGCGGTACCT GGCCATGAAC 
AAGAGGGGAC GACTCTATGC TTCGGAGCAC TACAGCGCCG AGTGCGAGTT TGTGGAGCGG 
ATCCACGAGC TGGGCTATAA TACGTATGCC TCCCGGCTGT ACCGGACGGT GTCTAGTACG 
CCTGGGGCCC GCCGGCAGCC CAGCGCCGAG AGACTGTGGT ACGTGTCTGT GAACGGCAAG 
GGCCGGCCCC GCAGGGGCTT CAAGACCCGC CGCACACAGA AGTCCTCCCT GTTCCTGCCC 
CGCGTGCTGG ACCACAGGGA CCACGAGATG GTGCGGCAGC TACAGAGTGG GCTGCCCAGA 
CCCCCTGGTA AGGGGGTCCA GCCCCGACGG CGGCGGCAGA AGCAGAGCCC GGATAACCTG 
GAGCCCTCTC ACGTTCAGGC TTCGAGACTG GGCTCCCAGC TGGAGGCCAG TGCGCACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Inhibitory effects of int-2 gene on the invasion and metastasis of oral cancer cells.
European review for medical and pharmacological sciences21(24)5677-5682(2017 Dec)
Liu LM

HER2-Overexpressing Breast Cancers Amplify FGFR Signaling upon Acquisition of Resistance to Dual Therapeutic Blockade of HER2.
Clinical cancer research : an official journal of the American Association for Cancer Research23(15)4323-4334(2017 Aug)
Hanker AB,Garrett JT,Estrada MV,Moore PD,Ericsson PG,Koch JP,Langley E,Singh S,Kim PS,Frampton GM,Sanford E,Owens P,Becker J,Groseclose MR,Castellino S,Joensuu H,Huober J,Brase JC,Majjaj S,Broh?e S,Venet D,Brown D,Baselga J,Piccart M,Sotiriou C,Arteaga CL

Genetically confirmed thanatophoric dysplasia with fibroblast growth factor receptor 3 mutation.
Experimental and molecular pathology102(2)290-295(2017 04)
Jung M,Park SH

Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling.
Oncotarget6(31)30453-71(2015 Oct)
Lamb R,Bonuccelli G,Ozsv?ri B,Peiris-Pag?s M,Fiorillo M,Smith DL,Bevilacqua G,Mazzanti CM,McDonnell LA,Naccarato AG,Chiu M,Wynne L,Martinez-Outschoorn UE,Sotgia F,Lisanti MP

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FGF3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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