SP8 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SP8
Entrez Gene ID	221833
Full Name	Sp8 transcription factor
Synonyms	BTD
General protein information	Preferred Names Sp8 transcription factor Names transcription factor Sp8 specificity protein 8
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7p21.1
Summary	The protein encoded by this gene is an SP family transcription factor that in mouse has been shown to be essential for proper limb development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011].
Disorder MIM:	608306

mRNA and Protein(s)

mRNA	Protein	Name
NM_198956.4	NP_945194.1	transcription factor Sp8 isoform 2
NM_182700.6	NP_874359.2	transcription factor Sp8 isoform 1
NM_182700.5	NP_874359.2	transcription factor Sp8 isoform 1
NM_198956.3	NP_945194.1	transcription factor Sp8 isoform 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SP8	XP_001153018.2
Bos taurus (cattle)	SP8	XP_002686752.1
Danio rerio (zebrafish)	sp8b	NP_991113.1
Rattus norvegicus (Norway rat)	Sp8	NP_001178703.1
Gallus gallus (chicken)	SP8	NP_001185595.1
Xenopus tropicalis (tropical clawed frog)	sp8	XP_002933331.2
	SP8	XP_001102781.1
Mus musculus (house mouse)	Sp8	NP_796056.2
Caenorhabditis elegans (roundworm)	sptf-2	NP_495833.1
Homo sapiens (human)	SP8	NP_874359.2

Gene Ontology
Bibliography

Related articles in PubMed

The Transcription Factor p8 Regulates Autophagy in Response to Palmitic Acid Stress via a Mammalian Target of Rapamycin (mTOR)-independent Signaling Pathway.
Jia SN, Lin C, Chen DF, Li AQ, Dai L, Zhang L, Zhao LL, Yang JS, Yang F, Yang WJ
The Journal of biological chemistry291(9)4462-72(2016 Feb)

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
Eeles RA, Olama AA, Benlloch S, Saunders EJ, Leongamornlert DA, Tymrakiewicz M, Ghoussaini M, Luccarini C, Dennis J, Jugurnauth-Little S, Dadaev T, Neal DE, Hamdy FC, Donovan JL, Muir K, Giles GG, Severi G, Wiklund F, Gronberg H, Haiman CA, Schumacher F, Henderson BE, Le Marchand L, Lindstrom S, Kraft P, Hunter DJ, Gapstur S, Chanock SJ, Berndt SI, Albanes D, Andriole G, Schleutker J, Weischer M, Canzian F, Riboli E, Key TJ, Travis RC, Campa D, Ingles SA, John EM, Hayes RB, Pharoah PD, Pashayan N, Khaw KT, Stanford JL, Ostrander EA, Signorello LB, Thibodeau SN, Schaid D, Maier C, Vogel W, Kibel AS, Cybulski C, Lubinski J, Cannon-Albright L, Brenner H, Park JY, Kaneva R, Batra J, Spurdle AB, Clements JA, Teixeira MR, Dicks E, Lee A, Dunning AM, Baynes C, Conroy D, Maranian MJ, Ahmed S, Govindasami K, Guy M, Wilkinson RA, Sawyer EJ, Morgan A, Dearnaley DP, Horwich A, Huddart RA, Khoo VS, Parker CC, Van As NJ, Woodhouse CJ, Thompson A, Dudderidge T, Ogden C, Cooper CS, Lophatananon A, Cox A, Southey MC, Hopper JL, English DR, Aly M, Adolfsson J, Xu J, Zheng SL, Yeager M, Kaaks R, Diver WR, Gaudet MM, Stern MC, Corral R, Joshi AD, Shahabi A, Wahlfors T, Tammela TL, Auvinen A, Virtamo J, Klarskov P, Nordestgaard BG, R?der MA, Nielsen SF, Bojesen SE, Siddiq A, Fitzgerald LM, Kolb S, Kwon EM, Karyadi DM, Blot WJ, Zheng W, Cai Q, McDonnell SK, Rinckleb AE, Drake B, Colditz G, Wokolorczyk D, Stephenson RA, Teerlink C, Muller H, Rothenbacher D, Sellers TA, Lin HY, Slavov C, Mitev V, Lose F, Srinivasan S, Maia S, Paulo P, Lange E, Cooney KA, Antoniou AC, Vincent D, Bacot F, Tessier DC, , , , , , Kote-Jarai Z, Easton DF
Nature genetics45(4)385-91, 391e1-2(2013 Apr)

Genetic variants on 3q21 and in the Sp8 transcription factor gene (SP8) as susceptibility loci for psychotic disorders: a genetic association study.
Kondo K, Ikeda M, Kajio Y, Saito T, Iwayama Y, Aleksic B, Yamada K, Toyota T, Hattori E, Ujike H, Inada T, Kunugi H, Kato T, Yoshikawa T, Ozaki N, Iwata N
PloS one8(8)e70964(2013)

Genome-wide association study of bipolar I disorder in the Han Chinese population.
Lee MT, Chen CH, Lee CS, Chen CC, Chong MY, Ouyang WC, Chiu NY, Chuo LJ, Chen CY, Tan HK, Lane HY, Chang TJ, Lin CH, Jou SH, Hou YM, Feng J, Lai TJ, Tung CL, Chen TJ, Chang CJ, Lung FW, Chen CK, Shiah IS, Liu CY, Teng PR, Chen KH, Shen LJ, Cheng CS, Chang TP, Li CF, Chou CH, Chen CY, Wang KH, Fann CS, Wu JY, Chen YT, Cheng AT
Molecular psychiatry16(5)548-56(2011 May)

Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.
Jugessur A, Shi M, Gjessing HK, Lie RT, Wilcox AJ, Weinberg CR, Christensen K, Boyles AL, Daack-Hirsch S, Nguyen TT, Christiansen L, Lidral AC, Murray JC
PloS one5(7)e11493(2010 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest expression of transcription factor p8/SP8 is up-regulated in endoplasmic reticulum stress due to lipotoxicity; overexpression of SP8 up-regulates autophagy; autophagy due to lipotoxicity requires SP8; these reactions are mTOR-independent.
Title: The Transcription Factor p8 Regulates Autophagy in Response to Palmitic Acid Stress via a Mammalian Target of Rapamycin (mTOR)-independent Signaling Pathway.

Genetic variants on 3q21 and in the Sp8 transcription factor gene (SP8) as susceptibility loci for psychotic disorders.
Title: Genetic variants on 3q21 and in the Sp8 transcription factor gene (SP8) as susceptibility loci for psychotic disorders: a genetic association study.

This study provided that SP8 are associated with Bipolar I in the Han Chinese population
Title: Genome-wide association study of bipolar I disorder in the Han Chinese population.

Observational study of gene-disease association. (HuGE Navigator)
Title: Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.

The following SP8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SP8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15564	NM_182700.6 Latest version!	Homo sapiens Sp8 transcription factor (SP8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu28424	NM_198956.4 Latest version!	Homo sapiens Sp8 transcription factor (SP8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
View Old Accession Versions >>
OHu15564	NM_182700.5	Homo sapiens Sp8 transcription factor (SP8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu28424	NM_198956.3	Homo sapiens Sp8 transcription factor (SP8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SP8 ( NM_182700.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_874359.2 Homo sapiens Sp8 transcription factor (SP8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu15564
Clone ID Related Accession (Same CDS sequence)	NM_182700.6 , NM_182700.5
Accession Version	NM_182700.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1527bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-01
Organism	Homo sapiens(human)
Product	transcription factor Sp8 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY167047.1, AC005060.3, KF511006.1 and AI632278.1. On Jun 2, 2019 this sequence version replaced NM_182700.5. Transcript Variant: This variant (1) represents the shorter transcript but encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AY167047.1, DA866987.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2153427 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAACTT CACTTCTAGG GGAAGAACCG AGGTTGGGAT CGACTCCTCT GGCCATGCTT 
GCCGCTACCT GTAATAAGAT AGGCAGCCCC AGCCCGTCTC CCTCCTCCCT CTCGGACAGC 
TCTTCTTCCT TCGGCAAAGG CTTCCACCCC TGGAAACGCT CCTCGTCCTC TTCTTCCGCC 
AGCTGCAACG TAGTGGGTTC CAGTCTCTCA AGCTTCGGCG TGTCCGGGGC CTCCAGGAAC 
GGCGGCTCGT CCTCGGCGGC TGCGGCGGCC GCGGCAGCAG CCGCGGCTGC CGCGGCCCTG 
GTGTCCGACT CGTTCAGCTG CGGCGGCTCG CCTGGCTCCA GCGCCTTCTC CCTCACCTCC 
AGCAGCGCCG CAGCCGCCGC CGCCGCCGCC GCAGCCGCCG CCTCCAGCTC GCCCTTCGCC 
AACGACTACT CTGTTTTCCA GGCCCCCGGA GTTTCCGGGG GCAGCGGCGG CGGCGGCGGG 
GGCGGCGGCG GCGGCTCCTC CGCGCACTCG CAGGACGGCT CCCACCAGCC GGTGTTCATC 
TCCAAGGTGC ACACCTCTGT GGACGGGCTG CAGGGCATCT ACCCGCGGGT GGGCATGGCG 
CACCCGTACG AGTCGTGGTT TAAGCCCTCG CACCCGGGCC TGGGTGCTGC GGGCGAGGTG 
GGCTCGGCCG GCGCCTCCAG CTGGTGGGAC GTGGGGGCCG GCTGGATCGA CGTGCAGAAC 
CCGAACAGCG CGGCTGCGCT GCCCGGCTCG CTGCACCCTG CCGCCGGGGG GCTCCAAACC 
TCGCTGCACT CGCCGCTCGG AGGCTACAAC TCGGATTACT CGGGCCTGAG TCACTCGGCC 
TTCAGCAGCG GCGCCTCCTC GCACCTGCTC AGCCCCGCCG GGCAGCACCT CATGGACGGC 
TTCAAGCCAG TGCTACCCGG CTCCTACCCG GACTCGGCCC CGTCGCCGCT GGCCGGCGCG 
GGGGGCTCCA TGTTGAGCGC TGGGCCTTCG GCGCCGCTGG GGGGCTCCCC GCGCTCCTCA 
GCTCGCCGCT ACTCCGGCCG CGCCACCTGC GACTGCCCCA ACTGCCAGGA GGCAGAGCGG 
CTGGGCCCTG CCGGGGCGAG CTTGCGGCGC AAGGGCCTGC ACAGCTGCCA CATCCCGGGC 
TGCGGCAAGG TGTACGGCAA GACTTCGCAC CTCAAGGCGC ACCTGCGCTG GCACACGGGC 
GAGCGGCCCT TCGTGTGCAA CTGGCTTTTC TGCGGCAAGC GCTTCACGCG CTCCGACGAG 
CTGCAGCGGC ACCTGCGGAC CCACACCGGC GAGAAGCGCT TCGCCTGTCC AGTTTGCAAC 
AAGCGCTTCA TGCGCAGCGA CCACCTCAGC AAGCACGTGA AGACGCACAG TGGCGGCGGC 
GGCGGCGGCG GCTCGGCGGG CTCGGGCAGC GGCGGCAAGA AGGGCAGCGA CACCGACAGC 
GAGCACAGCG CCGCGGGCAG CCCGCCCTGC CACTCCCCAG AGCTGCTGCA GCCCCCCGAG 
CCCGGGCACC GCAACGGCCT AGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_874359.2
CDS	89..1615
Translation	MATSLLGEEPRLGSTPLAMLAATCNKIGSPSPSPSSLSDSSSSFGKGFHPWKRSSSSSSASCNVVGSSLSSFGVSGASRNGGSSSAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSSAHSQDGSHQPVFISKVHTSVDGLQGIYPRVGMAHPYESWFKPSHPGLGAAGEVGSAGASSWWDVGAGWIDVQNPNSAAALPGSLHPAAGGLQTSLHSPLGGYNSDYSGLSHSAFSSGASSHLLSPAGQHLMDGFKPVLPGSYPDSAPSPLAGAGGSMLSAGPSAPLGGSPRSSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHSGGGGGGGSAGSGSGGKKGSDTDSEHSAAGSPPCHSPELLQPPEPGHRNGLE

Target ORF information:

RefSeq Version	NM_182700.6
Organism	Homo sapiens(human)
Definition	Homo sapiens Sp8 transcription factor (SP8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182700.6

ORF Insert Sequence:

ATGGCAACTT CACTTCTAGG GGAAGAACCG AGGTTGGGAT CGACTCCTCT GGCCATGCTT 
GCCGCTACCT GTAATAAGAT AGGCAGCCCC AGCCCGTCTC CCTCCTCCCT CTCGGACAGC 
TCTTCTTCCT TCGGCAAAGG CTTCCACCCC TGGAAACGCT CCTCGTCCTC TTCTTCCGCC 
AGCTGCAACG TAGTGGGTTC CAGTCTCTCA AGCTTCGGCG TGTCCGGGGC CTCCAGGAAC 
GGCGGCTCGT CCTCGGCGGC TGCGGCGGCC GCGGCAGCAG CCGCGGCTGC CGCGGCCCTG 
GTGTCCGACT CGTTCAGCTG CGGCGGCTCG CCTGGCTCCA GCGCCTTCTC CCTCACCTCC 
AGCAGCGCCG CAGCCGCCGC CGCCGCCGCC GCAGCCGCCG CCTCCAGCTC GCCCTTCGCC 
AACGACTACT CTGTTTTCCA GGCCCCCGGA GTTTCCGGGG GCAGCGGCGG CGGCGGCGGG 
GGCGGCGGCG GCGGCTCCTC CGCGCACTCG CAGGACGGCT CCCACCAGCC GGTGTTCATC 
TCCAAGGTGC ACACCTCTGT GGACGGGCTG CAGGGCATCT ACCCGCGGGT GGGCATGGCG 
CACCCGTACG AGTCGTGGTT TAAGCCCTCG CACCCGGGCC TGGGTGCTGC GGGCGAGGTG 
GGCTCGGCCG GCGCCTCCAG CTGGTGGGAC GTGGGGGCCG GCTGGATCGA CGTGCAGAAC 
CCGAACAGCG CGGCTGCGCT GCCCGGCTCG CTGCACCCTG CCGCCGGGGG GCTCCAAACC 
TCGCTGCACT CGCCGCTCGG AGGCTACAAC TCGGATTACT CGGGCCTGAG TCACTCGGCC 
TTCAGCAGCG GCGCCTCCTC GCACCTGCTC AGCCCCGCCG GGCAGCACCT CATGGACGGC 
TTCAAGCCAG TGCTACCCGG CTCCTACCCG GACTCGGCCC CGTCGCCGCT GGCCGGCGCG 
GGGGGCTCCA TGTTGAGCGC TGGGCCTTCG GCGCCGCTGG GGGGCTCCCC GCGCTCCTCA 
GCTCGCCGCT ACTCCGGCCG CGCCACCTGC GACTGCCCCA ACTGCCAGGA GGCAGAGCGG 
CTGGGCCCTG CCGGGGCGAG CTTGCGGCGC AAGGGCCTGC ACAGCTGCCA CATCCCGGGC 
TGCGGCAAGG TGTACGGCAA GACTTCGCAC CTCAAGGCGC ACCTGCGCTG GCACACGGGC 
GAGCGGCCCT TCGTGTGCAA CTGGCTTTTC TGCGGCAAGC GCTTCACGCG CTCCGACGAG 
CTGCAGCGGC ACCTGCGGAC CCACACCGGC GAGAAGCGCT TCGCCTGTCC AGTTTGCAAC 
AAGCGCTTCA TGCGCAGCGA CCACCTCAGC AAGCACGTGA AGACGCACAG TGGCGGCGGC 
GGCGGCGGCG GCTCGGCGGG CTCGGGCAGC GGCGGCAAGA AGGGCAGCGA CACCGACAGC 
GAGCACAGCG CCGCGGGCAG CCCGCCCTGC CACTCCCCAG AGCTGCTGCA GCCCCCCGAG 
CCCGGGCACC GCAACGGCCT AGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SP8 ( NM_182700.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_874359.2 Homo sapiens Sp8 transcription factor (SP8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu15564
Clone ID Related Accession (Same CDS sequence)	NM_182700.6 , NM_182700.5
Accession Version	NM_182700.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1527bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	transcription factor Sp8 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290465.1, AY167047.1, AC005060.3, KF511006.1 and AI632278.1. On Apr 12, 2014 this sequence version replaced NM_182700.4. Transcript Variant: This variant (1) represents the shorter transcript but encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AY167047.1, DA228021.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2153427 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAACTT CACTTCTAGG GGAAGAACCG AGGTTGGGAT CGACTCCTCT GGCCATGCTT 
GCCGCTACCT GTAATAAGAT AGGCAGCCCC AGCCCGTCTC CCTCCTCCCT CTCGGACAGC 
TCTTCTTCCT TCGGCAAAGG CTTCCACCCC TGGAAACGCT CCTCGTCCTC TTCTTCCGCC 
AGCTGCAACG TAGTGGGTTC CAGTCTCTCA AGCTTCGGCG TGTCCGGGGC CTCCAGGAAC 
GGCGGCTCGT CCTCGGCGGC TGCGGCGGCC GCGGCAGCAG CCGCGGCTGC CGCGGCCCTG 
GTGTCCGACT CGTTCAGCTG CGGCGGCTCG CCTGGCTCCA GCGCCTTCTC CCTCACCTCC 
AGCAGCGCCG CAGCCGCCGC CGCCGCCGCC GCAGCCGCCG CCTCCAGCTC GCCCTTCGCC 
AACGACTACT CTGTTTTCCA GGCCCCCGGA GTTTCCGGGG GCAGCGGCGG CGGCGGCGGG 
GGCGGCGGCG GCGGCTCCTC CGCGCACTCG CAGGACGGCT CCCACCAGCC GGTGTTCATC 
TCCAAGGTGC ACACCTCTGT GGACGGGCTG CAGGGCATCT ACCCGCGGGT GGGCATGGCG 
CACCCGTACG AGTCGTGGTT TAAGCCCTCG CACCCGGGCC TGGGTGCTGC GGGCGAGGTG 
GGCTCGGCCG GCGCCTCCAG CTGGTGGGAC GTGGGGGCCG GCTGGATCGA CGTGCAGAAC 
CCGAACAGCG CGGCTGCGCT GCCCGGCTCG CTGCACCCTG CCGCCGGGGG GCTCCAAACC 
TCGCTGCACT CGCCGCTCGG AGGCTACAAC TCGGATTACT CGGGCCTGAG TCACTCGGCC 
TTCAGCAGCG GCGCCTCCTC GCACCTGCTC AGCCCCGCCG GGCAGCACCT CATGGACGGC 
TTCAAGCCAG TGCTACCCGG CTCCTACCCG GACTCGGCCC CGTCGCCGCT GGCCGGCGCG 
GGGGGCTCCA TGTTGAGCGC TGGGCCTTCG GCGCCGCTGG GGGGCTCCCC GCGCTCCTCA 
GCTCGCCGCT ACTCCGGCCG CGCCACCTGC GACTGCCCCA ACTGCCAGGA GGCAGAGCGG 
CTGGGCCCTG CCGGGGCGAG CTTGCGGCGC AAGGGCCTGC ACAGCTGCCA CATCCCGGGC 
TGCGGCAAGG TGTACGGCAA GACTTCGCAC CTCAAGGCGC ACCTGCGCTG GCACACGGGC 
GAGCGGCCCT TCGTGTGCAA CTGGCTTTTC TGCGGCAAGC GCTTCACGCG CTCCGACGAG 
CTGCAGCGGC ACCTGCGGAC CCACACCGGC GAGAAGCGCT TCGCCTGTCC AGTTTGCAAC 
AAGCGCTTCA TGCGCAGCGA CCACCTCAGC AAGCACGTGA AGACGCACAG TGGCGGCGGC 
GGCGGCGGCG GCTCGGCGGG CTCGGGCAGC GGCGGCAAGA AGGGCAGCGA CACCGACAGC 
GAGCACAGCG CCGCGGGCAG CCCGCCCTGC CACTCCCCAG AGCTGCTGCA GCCCCCCGAG 
CCCGGGCACC GCAACGGCCT AGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_874359.2
CDS	92..1618
Translation	MATSLLGEEPRLGSTPLAMLAATCNKIGSPSPSPSSLSDSSSSFGKGFHPWKRSSSSSSASCNVVGSSLSSFGVSGASRNGGSSSAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSSAHSQDGSHQPVFISKVHTSVDGLQGIYPRVGMAHPYESWFKPSHPGLGAAGEVGSAGASSWWDVGAGWIDVQNPNSAAALPGSLHPAAGGLQTSLHSPLGGYNSDYSGLSHSAFSSGASSHLLSPAGQHLMDGFKPVLPGSYPDSAPSPLAGAGGSMLSAGPSAPLGGSPRSSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHSGGGGGGGSAGSGSGGKKGSDTDSEHSAAGSPPCHSPELLQPPEPGHRNGLE

Target ORF information:

RefSeq Version	NM_182700.5
Organism	Homo sapiens(human)
Definition	Homo sapiens Sp8 transcription factor (SP8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182700.5

ORF Insert Sequence:

ATGGCAACTT CACTTCTAGG GGAAGAACCG AGGTTGGGAT CGACTCCTCT GGCCATGCTT 
GCCGCTACCT GTAATAAGAT AGGCAGCCCC AGCCCGTCTC CCTCCTCCCT CTCGGACAGC 
TCTTCTTCCT TCGGCAAAGG CTTCCACCCC TGGAAACGCT CCTCGTCCTC TTCTTCCGCC 
AGCTGCAACG TAGTGGGTTC CAGTCTCTCA AGCTTCGGCG TGTCCGGGGC CTCCAGGAAC 
GGCGGCTCGT CCTCGGCGGC TGCGGCGGCC GCGGCAGCAG CCGCGGCTGC CGCGGCCCTG 
GTGTCCGACT CGTTCAGCTG CGGCGGCTCG CCTGGCTCCA GCGCCTTCTC CCTCACCTCC 
AGCAGCGCCG CAGCCGCCGC CGCCGCCGCC GCAGCCGCCG CCTCCAGCTC GCCCTTCGCC 
AACGACTACT CTGTTTTCCA GGCCCCCGGA GTTTCCGGGG GCAGCGGCGG CGGCGGCGGG 
GGCGGCGGCG GCGGCTCCTC CGCGCACTCG CAGGACGGCT CCCACCAGCC GGTGTTCATC 
TCCAAGGTGC ACACCTCTGT GGACGGGCTG CAGGGCATCT ACCCGCGGGT GGGCATGGCG 
CACCCGTACG AGTCGTGGTT TAAGCCCTCG CACCCGGGCC TGGGTGCTGC GGGCGAGGTG 
GGCTCGGCCG GCGCCTCCAG CTGGTGGGAC GTGGGGGCCG GCTGGATCGA CGTGCAGAAC 
CCGAACAGCG CGGCTGCGCT GCCCGGCTCG CTGCACCCTG CCGCCGGGGG GCTCCAAACC 
TCGCTGCACT CGCCGCTCGG AGGCTACAAC TCGGATTACT CGGGCCTGAG TCACTCGGCC 
TTCAGCAGCG GCGCCTCCTC GCACCTGCTC AGCCCCGCCG GGCAGCACCT CATGGACGGC 
TTCAAGCCAG TGCTACCCGG CTCCTACCCG GACTCGGCCC CGTCGCCGCT GGCCGGCGCG 
GGGGGCTCCA TGTTGAGCGC TGGGCCTTCG GCGCCGCTGG GGGGCTCCCC GCGCTCCTCA 
GCTCGCCGCT ACTCCGGCCG CGCCACCTGC GACTGCCCCA ACTGCCAGGA GGCAGAGCGG 
CTGGGCCCTG CCGGGGCGAG CTTGCGGCGC AAGGGCCTGC ACAGCTGCCA CATCCCGGGC 
TGCGGCAAGG TGTACGGCAA GACTTCGCAC CTCAAGGCGC ACCTGCGCTG GCACACGGGC 
GAGCGGCCCT TCGTGTGCAA CTGGCTTTTC TGCGGCAAGC GCTTCACGCG CTCCGACGAG 
CTGCAGCGGC ACCTGCGGAC CCACACCGGC GAGAAGCGCT TCGCCTGTCC AGTTTGCAAC 
AAGCGCTTCA TGCGCAGCGA CCACCTCAGC AAGCACGTGA AGACGCACAG TGGCGGCGGC 
GGCGGCGGCG GCTCGGCGGG CTCGGGCAGC GGCGGCAAGA AGGGCAGCGA CACCGACAGC 
GAGCACAGCG CCGCGGGCAG CCCGCCCTGC CACTCCCCAG AGCTGCTGCA GCCCCCCGAG 
CCCGGGCACC GCAACGGCCT AGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SP8 ( NM_198956.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_945194.1 Homo sapiens Sp8 transcription factor (SP8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu28424
Clone ID Related Accession (Same CDS sequence)	NM_198956.4 , NM_198956.3
Accession Version	NM_198956.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-18
Organism	Homo sapiens(human)
Product	transcription factor Sp8 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290465.1, DA497089.1, AC005060.3, KF511006.1 and AI632278.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_198956.3. Transcript Variant: This variant (2) includes an alternate internal exon and initiates translation from a downstream start codon, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK307969.1, DA497089.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2153427 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTTGCCG CTACCTGTAA TAAGATAGGC AGCCCCAGCC CGTCTCCCTC CTCCCTCTCG 
GACAGCTCTT CTTCCTTCGG CAAAGGCTTC CACCCCTGGA AACGCTCCTC GTCCTCTTCT 
TCCGCCAGCT GCAACGTAGT GGGTTCCAGT CTCTCAAGCT TCGGCGTGTC CGGGGCCTCC 
AGGAACGGCG GCTCGTCCTC GGCGGCTGCG GCGGCCGCGG CAGCAGCCGC GGCTGCCGCG 
GCCCTGGTGT CCGACTCGTT CAGCTGCGGC GGCTCGCCTG GCTCCAGCGC CTTCTCCCTC 
ACCTCCAGCA GCGCCGCAGC CGCCGCCGCC GCCGCCGCAG CCGCCGCCTC CAGCTCGCCC 
TTCGCCAACG ACTACTCTGT TTTCCAGGCC CCCGGAGTTT CCGGGGGCAG CGGCGGCGGC 
GGCGGGGGCG GCGGCGGCGG CTCCTCCGCG CACTCGCAGG ACGGCTCCCA CCAGCCGGTG 
TTCATCTCCA AGGTGCACAC CTCTGTGGAC GGGCTGCAGG GCATCTACCC GCGGGTGGGC 
ATGGCGCACC CGTACGAGTC GTGGTTTAAG CCCTCGCACC CGGGCCTGGG TGCTGCGGGC 
GAGGTGGGCT CGGCCGGCGC CTCCAGCTGG TGGGACGTGG GGGCCGGCTG GATCGACGTG 
CAGAACCCGA ACAGCGCGGC TGCGCTGCCC GGCTCGCTGC ACCCTGCCGC CGGGGGGCTC 
CAAACCTCGC TGCACTCGCC GCTCGGAGGC TACAACTCGG ATTACTCGGG CCTGAGTCAC 
TCGGCCTTCA GCAGCGGCGC CTCCTCGCAC CTGCTCAGCC CCGCCGGGCA GCACCTCATG 
GACGGCTTCA AGCCAGTGCT ACCCGGCTCC TACCCGGACT CGGCCCCGTC GCCGCTGGCC 
GGCGCGGGGG GCTCCATGTT GAGCGCTGGG CCTTCGGCGC CGCTGGGGGG CTCCCCGCGC 
TCCTCAGCTC GCCGCTACTC CGGCCGCGCC ACCTGCGACT GCCCCAACTG CCAGGAGGCA 
GAGCGGCTGG GCCCTGCCGG GGCGAGCTTG CGGCGCAAGG GCCTGCACAG CTGCCACATC 
CCGGGCTGCG GCAAGGTGTA CGGCAAGACT TCGCACCTCA AGGCGCACCT GCGCTGGCAC 
ACGGGCGAGC GGCCCTTCGT GTGCAACTGG CTTTTCTGCG GCAAGCGCTT CACGCGCTCC 
GACGAGCTGC AGCGGCACCT GCGGACCCAC ACCGGCGAGA AGCGCTTCGC CTGTCCAGTT 
TGCAACAAGC GCTTCATGCG CAGCGACCAC CTCAGCAAGC ACGTGAAGAC GCACAGTGGC 
GGCGGCGGCG GCGGCGGCTC GGCGGGCTCG GGCAGCGGCG GCAAGAAGGG CAGCGACACC 
GACAGCGAGC ACAGCGCCGC GGGCAGCCCG CCCTGCCACT CCCCAGAGCT GCTGCAGCCC 
CCCGAGCCCG GGCACCGCAA CGGCCTAGAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_945194.1
CDS	239..1711
Translation	MLAATCNKIGSPSPSPSSLSDSSSSFGKGFHPWKRSSSSSSASCNVVGSSLSSFGVSGASRNGGSSSAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSSAHSQDGSHQPVFISKVHTSVDGLQGIYPRVGMAHPYESWFKPSHPGLGAAGEVGSAGASSWWDVGAGWIDVQNPNSAAALPGSLHPAAGGLQTSLHSPLGGYNSDYSGLSHSAFSSGASSHLLSPAGQHLMDGFKPVLPGSYPDSAPSPLAGAGGSMLSAGPSAPLGGSPRSSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHSGGGGGGGSAGSGSGGKKGSDTDSEHSAAGSPPCHSPELLQPPEPGHRNGLE

Target ORF information:

RefSeq Version	NM_198956.4
Organism	Homo sapiens(human)
Definition	Homo sapiens Sp8 transcription factor (SP8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198956.4

ORF Insert Sequence:

ATGCTTGCCG CTACCTGTAA TAAGATAGGC AGCCCCAGCC CGTCTCCCTC CTCCCTCTCG 
GACAGCTCTT CTTCCTTCGG CAAAGGCTTC CACCCCTGGA AACGCTCCTC GTCCTCTTCT 
TCCGCCAGCT GCAACGTAGT GGGTTCCAGT CTCTCAAGCT TCGGCGTGTC CGGGGCCTCC 
AGGAACGGCG GCTCGTCCTC GGCGGCTGCG GCGGCCGCGG CAGCAGCCGC GGCTGCCGCG 
GCCCTGGTGT CCGACTCGTT CAGCTGCGGC GGCTCGCCTG GCTCCAGCGC CTTCTCCCTC 
ACCTCCAGCA GCGCCGCAGC CGCCGCCGCC GCCGCCGCAG CCGCCGCCTC CAGCTCGCCC 
TTCGCCAACG ACTACTCTGT TTTCCAGGCC CCCGGAGTTT CCGGGGGCAG CGGCGGCGGC 
GGCGGGGGCG GCGGCGGCGG CTCCTCCGCG CACTCGCAGG ACGGCTCCCA CCAGCCGGTG 
TTCATCTCCA AGGTGCACAC CTCTGTGGAC GGGCTGCAGG GCATCTACCC GCGGGTGGGC 
ATGGCGCACC CGTACGAGTC GTGGTTTAAG CCCTCGCACC CGGGCCTGGG TGCTGCGGGC 
GAGGTGGGCT CGGCCGGCGC CTCCAGCTGG TGGGACGTGG GGGCCGGCTG GATCGACGTG 
CAGAACCCGA ACAGCGCGGC TGCGCTGCCC GGCTCGCTGC ACCCTGCCGC CGGGGGGCTC 
CAAACCTCGC TGCACTCGCC GCTCGGAGGC TACAACTCGG ATTACTCGGG CCTGAGTCAC 
TCGGCCTTCA GCAGCGGCGC CTCCTCGCAC CTGCTCAGCC CCGCCGGGCA GCACCTCATG 
GACGGCTTCA AGCCAGTGCT ACCCGGCTCC TACCCGGACT CGGCCCCGTC GCCGCTGGCC 
GGCGCGGGGG GCTCCATGTT GAGCGCTGGG CCTTCGGCGC CGCTGGGGGG CTCCCCGCGC 
TCCTCAGCTC GCCGCTACTC CGGCCGCGCC ACCTGCGACT GCCCCAACTG CCAGGAGGCA 
GAGCGGCTGG GCCCTGCCGG GGCGAGCTTG CGGCGCAAGG GCCTGCACAG CTGCCACATC 
CCGGGCTGCG GCAAGGTGTA CGGCAAGACT TCGCACCTCA AGGCGCACCT GCGCTGGCAC 
ACGGGCGAGC GGCCCTTCGT GTGCAACTGG CTTTTCTGCG GCAAGCGCTT CACGCGCTCC 
GACGAGCTGC AGCGGCACCT GCGGACCCAC ACCGGCGAGA AGCGCTTCGC CTGTCCAGTT 
TGCAACAAGC GCTTCATGCG CAGCGACCAC CTCAGCAAGC ACGTGAAGAC GCACAGTGGC 
GGCGGCGGCG GCGGCGGCTC GGCGGGCTCG GGCAGCGGCG GCAAGAAGGG CAGCGACACC 
GACAGCGAGC ACAGCGCCGC GGGCAGCCCG CCCTGCCACT CCCCAGAGCT GCTGCAGCCC 
CCCGAGCCCG GGCACCGCAA CGGCCTAGAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SP8 ( NM_198956.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_945194.1 Homo sapiens Sp8 transcription factor (SP8), transcript variant 2, mRNA.

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CloneID	OHu28424
Clone ID Related Accession (Same CDS sequence)	NM_198956.4 , NM_198956.3
Accession Version	NM_198956.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	transcription factor Sp8 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290465.1, DA497089.1, AC005060.3, KF511006.1 and AI632278.1. This sequence is a reference standard in the RefSeqGene project. On Apr 12, 2014 this sequence version replaced NM_198956.2. Transcript Variant: This variant (2) includes an alternate internal exon and initiates translation from a downstream start codon, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK307969.1, DA497089.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMEA2153427 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTTGCCG CTACCTGTAA TAAGATAGGC AGCCCCAGCC CGTCTCCCTC CTCCCTCTCG 
GACAGCTCTT CTTCCTTCGG CAAAGGCTTC CACCCCTGGA AACGCTCCTC GTCCTCTTCT 
TCCGCCAGCT GCAACGTAGT GGGTTCCAGT CTCTCAAGCT TCGGCGTGTC CGGGGCCTCC 
AGGAACGGCG GCTCGTCCTC GGCGGCTGCG GCGGCCGCGG CAGCAGCCGC GGCTGCCGCG 
GCCCTGGTGT CCGACTCGTT CAGCTGCGGC GGCTCGCCTG GCTCCAGCGC CTTCTCCCTC 
ACCTCCAGCA GCGCCGCAGC CGCCGCCGCC GCCGCCGCAG CCGCCGCCTC CAGCTCGCCC 
TTCGCCAACG ACTACTCTGT TTTCCAGGCC CCCGGAGTTT CCGGGGGCAG CGGCGGCGGC 
GGCGGGGGCG GCGGCGGCGG CTCCTCCGCG CACTCGCAGG ACGGCTCCCA CCAGCCGGTG 
TTCATCTCCA AGGTGCACAC CTCTGTGGAC GGGCTGCAGG GCATCTACCC GCGGGTGGGC 
ATGGCGCACC CGTACGAGTC GTGGTTTAAG CCCTCGCACC CGGGCCTGGG TGCTGCGGGC 
GAGGTGGGCT CGGCCGGCGC CTCCAGCTGG TGGGACGTGG GGGCCGGCTG GATCGACGTG 
CAGAACCCGA ACAGCGCGGC TGCGCTGCCC GGCTCGCTGC ACCCTGCCGC CGGGGGGCTC 
CAAACCTCGC TGCACTCGCC GCTCGGAGGC TACAACTCGG ATTACTCGGG CCTGAGTCAC 
TCGGCCTTCA GCAGCGGCGC CTCCTCGCAC CTGCTCAGCC CCGCCGGGCA GCACCTCATG 
GACGGCTTCA AGCCAGTGCT ACCCGGCTCC TACCCGGACT CGGCCCCGTC GCCGCTGGCC 
GGCGCGGGGG GCTCCATGTT GAGCGCTGGG CCTTCGGCGC CGCTGGGGGG CTCCCCGCGC 
TCCTCAGCTC GCCGCTACTC CGGCCGCGCC ACCTGCGACT GCCCCAACTG CCAGGAGGCA 
GAGCGGCTGG GCCCTGCCGG GGCGAGCTTG CGGCGCAAGG GCCTGCACAG CTGCCACATC 
CCGGGCTGCG GCAAGGTGTA CGGCAAGACT TCGCACCTCA AGGCGCACCT GCGCTGGCAC 
ACGGGCGAGC GGCCCTTCGT GTGCAACTGG CTTTTCTGCG GCAAGCGCTT CACGCGCTCC 
GACGAGCTGC AGCGGCACCT GCGGACCCAC ACCGGCGAGA AGCGCTTCGC CTGTCCAGTT 
TGCAACAAGC GCTTCATGCG CAGCGACCAC CTCAGCAAGC ACGTGAAGAC GCACAGTGGC 
GGCGGCGGCG GCGGCGGCTC GGCGGGCTCG GGCAGCGGCG GCAAGAAGGG CAGCGACACC 
GACAGCGAGC ACAGCGCCGC GGGCAGCCCG CCCTGCCACT CCCCAGAGCT GCTGCAGCCC 
CCCGAGCCCG GGCACCGCAA CGGCCTAGAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_945194.1
CDS	242..1714
Translation	MLAATCNKIGSPSPSPSSLSDSSSSFGKGFHPWKRSSSSSSASCNVVGSSLSSFGVSGASRNGGSSSAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSSAHSQDGSHQPVFISKVHTSVDGLQGIYPRVGMAHPYESWFKPSHPGLGAAGEVGSAGASSWWDVGAGWIDVQNPNSAAALPGSLHPAAGGLQTSLHSPLGGYNSDYSGLSHSAFSSGASSHLLSPAGQHLMDGFKPVLPGSYPDSAPSPLAGAGGSMLSAGPSAPLGGSPRSSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHVKTHSGGGGGGGSAGSGSGGKKGSDTDSEHSAAGSPPCHSPELLQPPEPGHRNGLE

Target ORF information:

RefSeq Version	NM_198956.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Sp8 transcription factor (SP8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198956.3

ORF Insert Sequence:

ATGCTTGCCG CTACCTGTAA TAAGATAGGC AGCCCCAGCC CGTCTCCCTC CTCCCTCTCG 
GACAGCTCTT CTTCCTTCGG CAAAGGCTTC CACCCCTGGA AACGCTCCTC GTCCTCTTCT 
TCCGCCAGCT GCAACGTAGT GGGTTCCAGT CTCTCAAGCT TCGGCGTGTC CGGGGCCTCC 
AGGAACGGCG GCTCGTCCTC GGCGGCTGCG GCGGCCGCGG CAGCAGCCGC GGCTGCCGCG 
GCCCTGGTGT CCGACTCGTT CAGCTGCGGC GGCTCGCCTG GCTCCAGCGC CTTCTCCCTC 
ACCTCCAGCA GCGCCGCAGC CGCCGCCGCC GCCGCCGCAG CCGCCGCCTC CAGCTCGCCC 
TTCGCCAACG ACTACTCTGT TTTCCAGGCC CCCGGAGTTT CCGGGGGCAG CGGCGGCGGC 
GGCGGGGGCG GCGGCGGCGG CTCCTCCGCG CACTCGCAGG ACGGCTCCCA CCAGCCGGTG 
TTCATCTCCA AGGTGCACAC CTCTGTGGAC GGGCTGCAGG GCATCTACCC GCGGGTGGGC 
ATGGCGCACC CGTACGAGTC GTGGTTTAAG CCCTCGCACC CGGGCCTGGG TGCTGCGGGC 
GAGGTGGGCT CGGCCGGCGC CTCCAGCTGG TGGGACGTGG GGGCCGGCTG GATCGACGTG 
CAGAACCCGA ACAGCGCGGC TGCGCTGCCC GGCTCGCTGC ACCCTGCCGC CGGGGGGCTC 
CAAACCTCGC TGCACTCGCC GCTCGGAGGC TACAACTCGG ATTACTCGGG CCTGAGTCAC 
TCGGCCTTCA GCAGCGGCGC CTCCTCGCAC CTGCTCAGCC CCGCCGGGCA GCACCTCATG 
GACGGCTTCA AGCCAGTGCT ACCCGGCTCC TACCCGGACT CGGCCCCGTC GCCGCTGGCC 
GGCGCGGGGG GCTCCATGTT GAGCGCTGGG CCTTCGGCGC CGCTGGGGGG CTCCCCGCGC 
TCCTCAGCTC GCCGCTACTC CGGCCGCGCC ACCTGCGACT GCCCCAACTG CCAGGAGGCA 
GAGCGGCTGG GCCCTGCCGG GGCGAGCTTG CGGCGCAAGG GCCTGCACAG CTGCCACATC 
CCGGGCTGCG GCAAGGTGTA CGGCAAGACT TCGCACCTCA AGGCGCACCT GCGCTGGCAC 
ACGGGCGAGC GGCCCTTCGT GTGCAACTGG CTTTTCTGCG GCAAGCGCTT CACGCGCTCC 
GACGAGCTGC AGCGGCACCT GCGGACCCAC ACCGGCGAGA AGCGCTTCGC CTGTCCAGTT 
TGCAACAAGC GCTTCATGCG CAGCGACCAC CTCAGCAAGC ACGTGAAGAC GCACAGTGGC 
GGCGGCGGCG GCGGCGGCTC GGCGGGCTCG GGCAGCGGCG GCAAGAAGGG CAGCGACACC 
GACAGCGAGC ACAGCGCCGC GGGCAGCCCG CCCTGCCACT CCCCAGAGCT GCTGCAGCCC 
CCCGAGCCCG GGCACCGCAA CGGCCTAGAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The Transcription Factor p8 Regulates Autophagy in Response to Palmitic Acid Stress via a Mammalian Target of Rapamycin (mTOR)-independent Signaling Pathway.
The Journal of biological chemistry291(9)4462-72(2016 Feb)
Jia SN,Lin C,Chen DF,Li AQ,Dai L,Zhang L,Zhao LL,Yang JS,Yang F,Yang WJ

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
Nature genetics45(4)385-91, 391e1-2(2013 Apr)
Eeles RA,Olama AA,Benlloch S,Saunders EJ,Leongamornlert DA,Tymrakiewicz M,Ghoussaini M,Luccarini C,Dennis J,Jugurnauth-Little S,Dadaev T,Neal DE,Hamdy FC,Donovan JL,Muir K,Giles GG,Severi G,Wiklund F,Gronberg H,Haiman CA,Schumacher F,Henderson BE,Le Marchand L,Lindstrom S,Kraft P,Hunter DJ,Gapstur S,Chanock SJ,Berndt SI,Albanes D,Andriole G,Schleutker J,Weischer M,Canzian F,Riboli E,Key TJ,Travis RC,Campa D,Ingles SA,John EM,Hayes RB,Pharoah PD,Pashayan N,Khaw KT,Stanford JL,Ostrander EA,Signorello LB,Thibodeau SN,Schaid D,Maier C,Vogel W,Kibel AS,Cybulski C,Lubinski J,Cannon-Albright L,Brenner H,Park JY,Kaneva R,Batra J,Spurdle AB,Clements JA,Teixeira MR,Dicks E,Lee A,Dunning AM,Baynes C,Conroy D,Maranian MJ,Ahmed S,Govindasami K,Guy M,Wilkinson RA,Sawyer EJ,Morgan A,Dearnaley DP,Horwich A,Huddart RA,Khoo VS,Parker CC,Van As NJ,Woodhouse CJ,Thompson A,Dudderidge T,Ogden C,Cooper CS,Lophatananon A,Cox A,Southey MC,Hopper JL,English DR,Aly M,Adolfsson J,Xu J,Zheng SL,Yeager M,Kaaks R,Diver WR,Gaudet MM,Stern MC,Corral R,Joshi AD,Shahabi A,Wahlfors T,Tammela TL,Auvinen A,Virtamo J,Klarskov P,Nordestgaard BG,R?der MA,Nielsen SF,Bojesen SE,Siddiq A,Fitzgerald LM,Kolb S,Kwon EM,Karyadi DM,Blot WJ,Zheng W,Cai Q,McDonnell SK,Rinckleb AE,Drake B,Colditz G,Wokolorczyk D,Stephenson RA,Teerlink C,Muller H,Rothenbacher D,Sellers TA,Lin HY,Slavov C,Mitev V,Lose F,Srinivasan S,Maia S,Paulo P,Lange E,Cooney KA,Antoniou AC,Vincent D,Bacot F,Tessier DC,,,,,,Kote-Jarai Z,Easton DF

Genetic variants on 3q21 and in the Sp8 transcription factor gene (SP8) as susceptibility loci for psychotic disorders: a genetic association study.
PloS one8(8)e70964(2013)
Kondo K,Ikeda M,Kajio Y,Saito T,Iwayama Y,Aleksic B,Yamada K,Toyota T,Hattori E,Ujike H,Inada T,Kunugi H,Kato T,Yoshikawa T,Ozaki N,Iwata N

Genome-wide association study of bipolar I disorder in the Han Chinese population.
Molecular psychiatry16(5)548-56(2011 May)
Lee MT,Chen CH,Lee CS,Chen CC,Chong MY,Ouyang WC,Chiu NY,Chuo LJ,Chen CY,Tan HK,Lane HY,Chang TJ,Lin CH,Jou SH,Hou YM,Feng J,Lai TJ,Tung CL,Chen TJ,Chang CJ,Lung FW,Chen CK,Shiah IS,Liu CY,Teng PR,Chen KH,Shen LJ,Cheng CS,Chang TP,Li CF,Chou CH,Chen CY,Wang KH,Fann CS,Wu JY,Chen YT,Cheng AT

Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.
PloS one5(7)e11493(2010 Jul)
Jugessur A,Shi M,Gjessing HK,Lie RT,Wilcox AJ,Weinberg CR,Christensen K,Boyles AL,Daack-Hirsch S,Nguyen TT,Christiansen L,Lidral AC,Murray JC

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SP8 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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