Gene Symbol | FCGR2B |
Entrez Gene ID | 2213 |
Full Name | Fc fragment of IgG receptor IIb |
Synonyms | CD32,CD32B,FCG2,FCGR2,IGFR2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]. |
Disorder MIM: | |
Disorder Html: | {Systemic lupus erythematosus, susceptibility to}, 152700 (3); {Malaria, resistance to}, 611162 (3) |