Gene Symbol | ALKBH3 |
Entrez Gene ID | 221120 |
Full Name | alkB homolog 3, alpha-ketoglutaratedependent dioxygenase |
Synonyms | ABH3,DEPC-1,DEPC1,PCA1,hABH3 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008]. |
Disorder MIM: |