Gene Symbol | FAT2 |
Entrez Gene ID | 2196 |
Full Name | FAT atypical cadherin 2 |
Synonyms | CDHF8,CDHR9,HFAT2,MEGF1,SCA45 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene is the second identified human homolog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has two epidermal growth factor (EGF)-like repeats and one laminin G domain. This protein most likely functions as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Spinocerebellar ataxia 45, 617769 (3) |