GSX1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GSX1
Entrez Gene ID	219409
Full Name	GS homeobox 1
Synonyms	GSH1,Gsh-1
General protein information	Preferred Names GS homeobox 1 Names GS homeobox 1 GS homeo box protein 1 genomic screened homeo box 1 homeobox protein Gsh-1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 13 Map Location: 13q12.2
Disorder MIM:	616542

mRNA and Protein(s)

mRNA	Protein	Name
NM_145657.3	NP_663632.1	GS homeobox 1
NM_145657.2	NP_663632.1	GS homeobox 1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Gsx1	NP_032204.1
Xenopus tropicalis (tropical clawed frog)	gsx1	NP_001039254.1
Pan troglodytes (chimpanzee)	GSX1	XP_522643.3
	GSX1	XP_001096656.2
Bos taurus (cattle)	GSX1	NP_001098918.1
Homo sapiens (human)	GSX1	NP_663632.1
Rattus norvegicus (Norway rat)	Gsx1	NP_001178592.1
Canis lupus familiaris (dog)	GSX1	XP_003639921.1
Danio rerio (zebrafish)	gsx1	NP_001012251.1

Gene Ontology
Bibliography

Related articles in PubMed

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.
Wolpin BM, Rizzato C, Kraft P, Kooperberg C, Petersen GM, Wang Z, Arslan AA, Beane-Freeman L, Bracci PM, Buring J, Canzian F, Duell EJ, Gallinger S, Giles GG, Goodman GE, Goodman PJ, Jacobs EJ, Kamineni A, Klein AP, Kolonel LN, Kulke MH, Li D, Malats N, Olson SH, Risch HA, Sesso HD, Visvanathan K, White E, Zheng W, Abnet CC, Albanes D, Andreotti G, Austin MA, Barfield R, Basso D, Berndt SI, Boutron-Ruault MC, Brotzman M, B?chler MW, Bueno-de-Mesquita HB, Bugert P, Burdette L, Campa D, Caporaso NE, Capurso G, Chung C, Cotterchio M, Costello E, Elena J, Funel N, Gaziano JM, Giese NA, Giovannucci EL, Goggins M, Gorman MJ, Gross M, Haiman CA, Hassan M, Helzlsouer KJ, Henderson BE, Holly EA, Hu N, Hunter DJ, Innocenti F, Jenab M, Kaaks R, Key TJ, Khaw KT, Klein EA, Kogevinas M, Krogh V, Kupcinskas J, Kurtz RC, LaCroix A, Landi MT, Landi S, Le Marchand L, Mambrini A, Mannisto S, Milne RL, Nakamura Y, Oberg AL, Owzar K, Patel AV, Peeters PH, Peters U, Pezzilli R, Piepoli A, Porta M, Real FX, Riboli E, Rothman N, Scarpa A, Shu XO, Silverman DT, Soucek P, Sund M, Talar-Wojnarowska R, Taylor PR, Theodoropoulos GE, Thornquist M, Tj?nneland A, Tobias GS, Trichopoulos D, Vodicka P, Wactawski-Wende J, Wentzensen N, Wu C, Yu H, Yu K, Zeleniuch-Jacquotte A, Hoover R, Hartge P, Fuchs C, Chanock SJ, Stolzenberg-Solomon RS, Amundadottir LT
Nature genetics46(9)994-1000(2014 Sep)

Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Low SK, Chung S, Takahashi A, Zembutsu H, Mushiroda T, Kubo M, Nakamura Y
Cancer science104(8)1074-82(2013 Aug)

Molecular genetic screening of MBS1 locus on chromosome 13 for microdeletions and exclusion of FGF9, GSH1 and CDX2 as causative genes in patients with Moebius syndrome.
Uzumcu A, Karaman B, Toksoy G, Uyguner ZO, Candan S, Eris H, Tatli B, Geckinli B, Yuksel A, Kayserili H, Basaran S
European journal of medical genetics52(5)315-20(2009 Sep-Oct)

A census of human transcription factors: function, expression and evolution.
Vaquerizas JM, Kummerfeld SK, Teichmann SA, Luscombe NM
Nature reviews. Genetics10(4)252-63(2009 04)

Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.
Anney RJ, Lasky-Su J, O'D?shl?ine C, Kenny E, Neale BM, Mulligan A, Franke B, Zhou K, Chen W, Christiansen H, Arias-V?squez A, Banaschewski T, Buitelaar J, Ebstein R, Miranda A, Mulas F, Oades RD, Roeyers H, Rothenberger A, Sergeant J, Sonuga-Barke E, Steinhausen H, Asherson P, Faraone SV, Gill M
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics147B(8)1369-78(2008 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the study ruled out microdeletions on the critical region as a common cause of Moebius syndrome and excluded GSH1 gene
Title: Molecular genetic screening of MBS1 locus on chromosome 13 for microdeletions and exclusion of FGF9, GSH1 and CDX2 as causative genes in patients with Moebius syndrome.

The following GSX1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GSX1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu77884	NM_145657.3 Latest version!	Homo sapiens GS homeobox 1 (GSX1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
View Old Accession Versions >>
OHu77884	NM_145657.2	Homo sapiens GS homeobox 1 (GSX1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GSX1 ( NM_145657.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_663632.1 Homo sapiens GS homeobox 1 (GSX1), mRNA.

Price & Availability↑

CloneID	OHu77884
Clone ID Related Accession (Same CDS sequence)	NM_145657.3 , NM_145657.2
Accession Version	NM_145657.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 795bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	GS homeobox 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL390738.4 and AB044157.1. On May 17, 2019 this sequence version replaced NM_145657.2. ##Evidence-Data-START## Transcript exon combination :: AB044157.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000302945.3/ ENSP00000304331.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGCCGCGCT CCTTCCTGGT GGACTCGCTA GTGCTGCGCG AGGCGGGCGA GAAGAAGGCG 
CCCGAGGGCA GCCCGCCGCC GCTCTTCCCC TACGCTGTGC CCCCGCCGCA CGCGCTGCAC 
GGTCTCTCGC CTGGCGCCTG CCACGCGCGC AAGGCTGGGC TGCTGTGCGT GTGCCCGCTC 
TGCGTCACCG CCTCGCAGCT GCATGGGCCC CCCGGGCCGC CCGCGCTGCC TCTACTCAAG 
GCTTCCTTCC CACCCTTCGG CTCGCAGTAC TGCCACGCGC CCCTGGGCCG CCAGCACTCT 
GCTGTGTCGC CCGGGGTCGC TCACGGCCCG GCCGCCGCTG CTGCTGCCGC CGCGCTCTAC 
CAGACCTCCT ACCCGCTGCC TGACCCCAGG CAGTTCCACT GCATCTCTGT GGACAGCAGC 
TCTAACCAGC TGCCCAGCAG CAAGAGGATG CGCACGGCTT TCACCAGCAC GCAGCTGCTA 
GAGCTGGAGC GCGAGTTCGC TTCTAATATG TACCTGTCCC GCCTACGTCG CATCGAGATC 
GCGACCTACC TGAATCTGTC CGAGAAGCAG GTGAAGATCT GGTTTCAGAA CCGCCGAGTG 
AAGCACAAGA AGGAGGGCAA GGGCAGCAAC CATCGTGGCG GCGGCGGCGG GGGTGCCGGT 
GGTGGCGGGA GCGCACCGCA AGGCTGCAAG TGCGCATCGC TCTCCTCAGC CAAGTGCTCC 
GAGGATGACG ACGAATTGCC CATGTCTCCG TCCTCCTCAG GGAAGGACGA CCGGGATCTT 
ACGGTCACTC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_663632.1
CDS	209..1003
Translation	MPRSFLVDSLVLREAGEKKAPEGSPPPLFPYAVPPPHALHGLSPGACHARKAGLLCVCPLCVTASQLHGPPGPPALPLLKASFPPFGSQYCHAPLGRQHSAVSPGVAHGPAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDDDELPMSPSSSGKDDRDLTVTP

Target ORF information:

RefSeq Version	NM_145657.3
Organism	Homo sapiens(human)
Definition	Homo sapiens GS homeobox 1 (GSX1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145657.3

ORF Insert Sequence:

ATGCCGCGCT CCTTCCTGGT GGACTCGCTA GTGCTGCGCG AGGCGGGCGA GAAGAAGGCG 
CCCGAGGGCA GCCCGCCGCC GCTCTTCCCC TACGCTGTGC CCCCGCCGCA CGCGCTGCAC 
GGTCTCTCGC CTGGCGCCTG CCACGCGCGC AAGGCTGGGC TGCTGTGCGT GTGCCCGCTC 
TGCGTCACCG CCTCGCAGCT GCATGGGCCC CCCGGGCCGC CCGCGCTGCC TCTACTCAAG 
GCTTCCTTCC CACCCTTCGG CTCGCAGTAC TGCCACGCGC CCCTGGGCCG CCAGCACTCT 
GCTGTGTCGC CCGGGGTCGC TCACGGCCCG GCCGCCGCTG CTGCTGCCGC CGCGCTCTAC 
CAGACCTCCT ACCCGCTGCC TGACCCCAGG CAGTTCCACT GCATCTCTGT GGACAGCAGC 
TCTAACCAGC TGCCCAGCAG CAAGAGGATG CGCACGGCTT TCACCAGCAC GCAGCTGCTA 
GAGCTGGAGC GCGAGTTCGC TTCTAATATG TACCTGTCCC GCCTACGTCG CATCGAGATC 
GCGACCTACC TGAATCTGTC CGAGAAGCAG GTGAAGATCT GGTTTCAGAA CCGCCGAGTG 
AAGCACAAGA AGGAGGGCAA GGGCAGCAAC CATCGTGGCG GCGGCGGCGG GGGTGCCGGT 
GGTGGCGGGA GCGCACCGCA AGGCTGCAAG TGCGCATCGC TCTCCTCAGC CAAGTGCTCC 
GAGGATGACG ACGAATTGCC CATGTCTCCG TCCTCCTCAG GGAAGGACGA CCGGGATCTT 
ACGGTCACTC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GSX1 ( NM_145657.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_663632.1 Homo sapiens GS homeobox 1 (GSX1), mRNA.

Price & Availability↑

CloneID	OHu77884
Clone ID Related Accession (Same CDS sequence)	NM_145657.3 , NM_145657.2
Accession Version	NM_145657.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 795bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	GS homeobox 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB044157.1 and AL390738.4. On Dec 18, 2014 this sequence version replaced NM_145657.1. ##Evidence-Data-START## Transcript exon combination :: AB044157.1 [ECO:0000332] ##Evidence-Data-END##

ATGCCGCGCT CCTTCCTGGT GGACTCGCTA GTGCTGCGCG AGGCGGGCGA GAAGAAGGCG 
CCCGAGGGCA GCCCGCCGCC GCTCTTCCCC TACGCTGTGC CCCCGCCGCA CGCGCTGCAC 
GGTCTCTCGC CTGGCGCCTG CCACGCGCGC AAGGCTGGGC TGCTGTGCGT GTGCCCGCTC 
TGCGTCACCG CCTCGCAGCT GCATGGGCCC CCCGGGCCGC CCGCGCTGCC TCTACTCAAG 
GCTTCCTTCC CACCCTTCGG CTCGCAGTAC TGCCACGCGC CCCTGGGCCG CCAGCACTCT 
GCTGTGTCGC CCGGGGTCGC TCACGGCCCG GCCGCCGCTG CTGCTGCCGC CGCGCTCTAC 
CAGACCTCCT ACCCGCTGCC TGACCCCAGG CAGTTCCACT GCATCTCTGT GGACAGCAGC 
TCTAACCAGC TGCCCAGCAG CAAGAGGATG CGCACGGCTT TCACCAGCAC GCAGCTGCTA 
GAGCTGGAGC GCGAGTTCGC TTCTAATATG TACCTGTCCC GCCTACGTCG CATCGAGATC 
GCGACCTACC TGAATCTGTC CGAGAAGCAG GTGAAGATCT GGTTTCAGAA CCGCCGAGTG 
AAGCACAAGA AGGAGGGCAA GGGCAGCAAC CATCGTGGCG GCGGCGGCGG GGGTGCCGGT 
GGTGGCGGGA GCGCACCGCA AGGCTGCAAG TGCGCATCGC TCTCCTCAGC CAAGTGCTCC 
GAGGATGACG ACGAATTGCC CATGTCTCCG TCCTCCTCAG GGAAGGACGA CCGGGATCTT 
ACGGTCACTC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_663632.1
CDS	49..843
Translation	MPRSFLVDSLVLREAGEKKAPEGSPPPLFPYAVPPPHALHGLSPGACHARKAGLLCVCPLCVTASQLHGPPGPPALPLLKASFPPFGSQYCHAPLGRQHSAVSPGVAHGPAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDDDELPMSPSSSGKDDRDLTVTP

Target ORF information:

RefSeq Version	NM_145657.2
Organism	Homo sapiens(human)
Definition	Homo sapiens GS homeobox 1 (GSX1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145657.2

ORF Insert Sequence:

ATGCCGCGCT CCTTCCTGGT GGACTCGCTA GTGCTGCGCG AGGCGGGCGA GAAGAAGGCG 
CCCGAGGGCA GCCCGCCGCC GCTCTTCCCC TACGCTGTGC CCCCGCCGCA CGCGCTGCAC 
GGTCTCTCGC CTGGCGCCTG CCACGCGCGC AAGGCTGGGC TGCTGTGCGT GTGCCCGCTC 
TGCGTCACCG CCTCGCAGCT GCATGGGCCC CCCGGGCCGC CCGCGCTGCC TCTACTCAAG 
GCTTCCTTCC CACCCTTCGG CTCGCAGTAC TGCCACGCGC CCCTGGGCCG CCAGCACTCT 
GCTGTGTCGC CCGGGGTCGC TCACGGCCCG GCCGCCGCTG CTGCTGCCGC CGCGCTCTAC 
CAGACCTCCT ACCCGCTGCC TGACCCCAGG CAGTTCCACT GCATCTCTGT GGACAGCAGC 
TCTAACCAGC TGCCCAGCAG CAAGAGGATG CGCACGGCTT TCACCAGCAC GCAGCTGCTA 
GAGCTGGAGC GCGAGTTCGC TTCTAATATG TACCTGTCCC GCCTACGTCG CATCGAGATC 
GCGACCTACC TGAATCTGTC CGAGAAGCAG GTGAAGATCT GGTTTCAGAA CCGCCGAGTG 
AAGCACAAGA AGGAGGGCAA GGGCAGCAAC CATCGTGGCG GCGGCGGCGG GGGTGCCGGT 
GGTGGCGGGA GCGCACCGCA AGGCTGCAAG TGCGCATCGC TCTCCTCAGC CAAGTGCTCC 
GAGGATGACG ACGAATTGCC CATGTCTCCG TCCTCCTCAG GGAAGGACGA CCGGGATCTT 
ACGGTCACTC CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.
Nature genetics46(9)994-1000(2014 Sep)
Wolpin BM,Rizzato C,Kraft P,Kooperberg C,Petersen GM,Wang Z,Arslan AA,Beane-Freeman L,Bracci PM,Buring J,Canzian F,Duell EJ,Gallinger S,Giles GG,Goodman GE,Goodman PJ,Jacobs EJ,Kamineni A,Klein AP,Kolonel LN,Kulke MH,Li D,Malats N,Olson SH,Risch HA,Sesso HD,Visvanathan K,White E,Zheng W,Abnet CC,Albanes D,Andreotti G,Austin MA,Barfield R,Basso D,Berndt SI,Boutron-Ruault MC,Brotzman M,B?chler MW,Bueno-de-Mesquita HB,Bugert P,Burdette L,Campa D,Caporaso NE,Capurso G,Chung C,Cotterchio M,Costello E,Elena J,Funel N,Gaziano JM,Giese NA,Giovannucci EL,Goggins M,Gorman MJ,Gross M,Haiman CA,Hassan M,Helzlsouer KJ,Henderson BE,Holly EA,Hu N,Hunter DJ,Innocenti F,Jenab M,Kaaks R,Key TJ,Khaw KT,Klein EA,Kogevinas M,Krogh V,Kupcinskas J,Kurtz RC,LaCroix A,Landi MT,Landi S,Le Marchand L,Mambrini A,Mannisto S,Milne RL,Nakamura Y,Oberg AL,Owzar K,Patel AV,Peeters PH,Peters U,Pezzilli R,Piepoli A,Porta M,Real FX,Riboli E,Rothman N,Scarpa A,Shu XO,Silverman DT,Soucek P,Sund M,Talar-Wojnarowska R,Taylor PR,Theodoropoulos GE,Thornquist M,Tj?nneland A,Tobias GS,Trichopoulos D,Vodicka P,Wactawski-Wende J,Wentzensen N,Wu C,Yu H,Yu K,Zeleniuch-Jacquotte A,Hoover R,Hartge P,Fuchs C,Chanock SJ,Stolzenberg-Solomon RS,Amundadottir LT

Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Cancer science104(8)1074-82(2013 Aug)
Low SK,Chung S,Takahashi A,Zembutsu H,Mushiroda T,Kubo M,Nakamura Y

Molecular genetic screening of MBS1 locus on chromosome 13 for microdeletions and exclusion of FGF9, GSH1 and CDX2 as causative genes in patients with Moebius syndrome.
European journal of medical genetics52(5)315-20(2009 Sep-Oct)
Uzumcu A,Karaman B,Toksoy G,Uyguner ZO,Candan S,Eris H,Tatli B,Geckinli B,Yuksel A,Kayserili H,Basaran S

A census of human transcription factors: function, expression and evolution.
Nature reviews. Genetics10(4)252-63(2009 04)
Vaquerizas JM,Kummerfeld SK,Teichmann SA,Luscombe NM

Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics147B(8)1369-78(2008 Dec)
Anney RJ,Lasky-Su J,O'D?shl?ine C,Kenny E,Neale BM,Mulligan A,Franke B,Zhou K,Chen W,Christiansen H,Arias-V?squez A,Banaschewski T,Buitelaar J,Ebstein R,Miranda A,Mulas F,Oades RD,Roeyers H,Rothenberger A,Sergeant J,Sonuga-Barke E,Steinhausen H,Asherson P,Faraone SV,Gill M

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GSX1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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