ATAD3C cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ATAD3C
Entrez Gene ID	219293
Full Name	ATPase family, AAA domain containing 3C
General protein information	Preferred Names ATPase family, AAA domain containing 3C Names ATPase family AAA domain-containing protein 3C ATPase family, AAA domain containing 3A
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p36.33
Disorder MIM:	617227

mRNA and Protein(s)

mRNA	Protein	Name
NM_001039211.2	NP_001034300.2	ATPase family AAA domain-containing protein 3C
NM_001039211.3	NP_001034300.2	ATPase family AAA domain-containing protein 3C

Pathways from BioSystems

Homologies

Homo sapiens (human)	ATAD3C	NP_001034300.2
Pan troglodytes (chimpanzee)	ATAD3C	XP_001146775.2

Gene Ontology
Bibliography

Related articles in PubMed

ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism.
Desai R, Frazier AE, Durigon R, Patel H, Jones AW, Dalla Rosa I, Lake NJ, Compton AG, Mountford HS, Tucker EJ, Mitchell ALR, Jackson D, Sesay A, Di Re M, van den Heuvel LP, Burke D, Francis D, Lunke S, McGillivray G, Mandelstam S, Mochel F, Keren B, Jardel C, Turner AM, Ian Andrews P, Smeitink J, Spelbrink JN, Heales SJ, Kohda M, Ohtake A, Murayama K, Okazaki Y, Lomb?s A, Holt IJ, Thorburn DR, Spinazzola A
Brain : a journal of neurology140(6)1595-1610(2017 Jun)

[ATAD3, a vital membrane-bound mitochondrial ATPase involved in tumor progression].
Li S, Rousseau D
Medecine sciences : M/S27(12)1089-95(2011 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ATAD3C region deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism.
Title: ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism.

ATAD3 may therefore be implicated in an unknown but essential and growth-linked mitochondrial function existing since pluri-cellular -organization and involved in tumorigenesis.
Title: [ATAD3, a vital membrane-bound mitochondrial ATPase involved in tumor progression].

The following ATAD3C gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ATAD3C cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24368	NM_001039211.3 Latest version!	Homo sapiens ATPase family AAA domain containing 3C (ATAD3C), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu24368	NM_001039211.2	Homo sapiens ATPase family AAA domain containing 3C (ATAD3C), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ATAD3C ( NM_001039211.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034300.2 Homo sapiens ATPase family AAA domain containing 3C (ATAD3C), mRNA.

Price & Availability↑

CloneID	OHu24368
Clone ID Related Accession (Same CDS sequence)	NM_001039211.2 , NM_001039211.3
Accession Version	NM_001039211.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1236bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-20
Organism	Homo sapiens(human)
Product	ATPase family AAA domain-containing protein 3C
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL391244.11 and AL157945.21. On Jul 10, 2008 this sequence version replaced NM_001039211.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK091918.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2159931 [ECO:0000348] ##Evidence-Data-END##

ATGTCAAAGG ACGCCCTGAA TCTGGCGCAG ATGCAGGAGC AGACGCTGCA GTTGGAGCAA 
CAGTCCAAGC TCAAACAACT TGTCAATGAG GATTTACGGA AGCAGGAGGA GTCCGTGCAG 
AAGCACCATC AGACCTTCTT GGAGTCCATC AGGGCGGCTG GCACCTTGTT TGGGGAAGGA 
TTCCGTGCCT TTGTGACAGA CCGGGACAAA GTGACAGCCA CGGTGGCTGG GCTGACGCTG 
CTGGCTGTCG GGGTCTACTC AGCCAAGAAT GCGACAGCCG TCACTGGCCG CTACATCGAG 
GCTCGGCTGG GGAAGCCGTC CCTAGTGAGG GAGACGTCCC GCATCACGGT GCTTGAGGCG 
CTGCGGCACC CCATCCAGCA GGTCAGCCGG CGGCTCCTCA GTCGACCCCA GGACGTGCTG 
GAGGGTGTTG TGCTTAGTCC CAGCCTGGAA GCACGGGTGC GCGACATCGC CATAATGACA 
AGGAACATCA AGAAGAACCG GGGCCTGTAC AGGCACATCC TGCTGTACGG GCCACCAGGC 
ACCGGGAAGA CGCTGTTTGC CAAGAAACTC GCCCTGCACT CAGGCATGGA CTACGCCATC 
ATGACAGGCG GGGACGTGGC CCCCATGGGG CGGGAAGGCG TGACCGCCAT GCACAAGCTC 
TTTGACTGGG CCAATACCAG CCGGCGCGGC CTCCTGCTCT TTGTGGATGA AGCGGACGCC 
TTCCTTCGGA AGCGAGCCAC TGAGAAGATA AGCGAGGACC TCAGGGCCAC ACTGAACGCC 
TTCCTGTACC GCACGGGCCA GCACAGCAAC AAATTCATGC TGATCCTGGC CAGCTGCCAC 
CCCGAGCAGT TCGACTGGGC CATCAATGCC TGCATCGACG TGATGGTCCA CTTCGACCTG 
CCAGGGCAGG AGGAGCGGGC GCGCCTGGTG AGAATGTATC TTAACGAGTA TGTTCTTAAG 
CCGGCCACAG AAGGAAAGCG GCGTCTGAAG CTGGCCCAGT TTGACTACGG GAGGAAGTGC 
TTAGAGATCG CTCGGCTGAC AGAGGGCATG TCATGCCGGA AGATCGCACA GCTGGCCGTG 
TCCTGGCAGG CCACGGCGTA TGCCTCCAAG GACGGGGTCC TGACCGAGGC CATGATGGAC 
GCCTGCGTGC AAGACTTTGT CCAGCAGCAC CAGCAGATGA TGCGCTGGCT GAAGGGGGAG 
AGGCCTGGGC CCGAGGACGA GCAACCCTCA TCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034300.2
CDS	996..2231
Translation	MSKDALNLAQMQEQTLQLEQQSKLKQLVNEDLRKQEESVQKHHQTFLESIRAAGTLFGEGFRAFVTDRDKVTATVAGLTLLAVGVYSAKNATAVTGRYIEARLGKPSLVRETSRITVLEALRHPIQQVSRRLLSRPQDVLEGVVLSPSLEARVRDIAIMTRNIKKNRGLYRHILLYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKLFDWANTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLYRTGQHSNKFMLILASCHPEQFDWAINACIDVMVHFDLPGQEERARLVRMYLNEYVLKPATEGKRRLKLAQFDYGRKCLEIARLTEGMSCRKIAQLAVSWQATAYASKDGVLTEAMMDACVQDFVQQHQQMMRWLKGERPGPEDEQPSS

Target ORF information:

RefSeq Version	NM_001039211.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ATPase family AAA domain containing 3C (ATAD3C), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039211.2

ORF Insert Sequence:

ATGTCAAAGG ACGCCCTGAA TCTGGCGCAG ATGCAGGAGC AGACGCTGCA GTTGGAGCAA 
CAGTCCAAGC TCAAACAACT TGTCAATGAG GATTTACGGA AGCAGGAGGA GTCCGTGCAG 
AAGCACCATC AGACCTTCTT GGAGTCCATC AGGGCGGCTG GCACCTTGTT TGGGGAAGGA 
TTCCGTGCCT TTGTGACAGA CCGGGACAAA GTGACAGCCA CGGTGGCTGG GCTGACGCTG 
CTGGCTGTCG GGGTCTACTC AGCCAAGAAT GCGACAGCCG TCACTGGCCG CTACATCGAG 
GCTCGGCTGG GGAAGCCGTC CCTAGTGAGG GAGACGTCCC GCATCACGGT GCTTGAGGCG 
CTGCGGCACC CCATCCAGCA GGTCAGCCGG CGGCTCCTCA GTCGACCCCA GGACGTGCTG 
GAGGGTGTTG TGCTTAGTCC CAGCCTGGAA GCACGGGTGC GCGACATCGC CATAATGACA 
AGGAACATCA AGAAGAACCG GGGCCTGTAC AGGCACATCC TGCTGTACGG GCCACCAGGC 
ACCGGGAAGA CGCTGTTTGC CAAGAAACTC GCCCTGCACT CAGGCATGGA CTACGCCATC 
ATGACAGGCG GGGACGTGGC CCCCATGGGG CGGGAAGGCG TGACCGCCAT GCACAAGCTC 
TTTGACTGGG CCAATACCAG CCGGCGCGGC CTCCTGCTCT TTGTGGATGA AGCGGACGCC 
TTCCTTCGGA AGCGAGCCAC TGAGAAGATA AGCGAGGACC TCAGGGCCAC ACTGAACGCC 
TTCCTGTACC GCACGGGCCA GCACAGCAAC AAATTCATGC TGATCCTGGC CAGCTGCCAC 
CCCGAGCAGT TCGACTGGGC CATCAATGCC TGCATCGACG TGATGGTCCA CTTCGACCTG 
CCAGGGCAGG AGGAGCGGGC GCGCCTGGTG AGAATGTATC TTAACGAGTA TGTTCTTAAG 
CCGGCCACAG AAGGAAAGCG GCGTCTGAAG CTGGCCCAGT TTGACTACGG GAGGAAGTGC 
TTAGAGATCG CTCGGCTGAC AGAGGGCATG TCATGCCGGA AGATCGCACA GCTGGCCGTG 
TCCTGGCAGG CCACGGCGTA TGCCTCCAAG GACGGGGTCC TGACCGAGGC CATGATGGAC 
GCCTGCGTGC AAGACTTTGT CCAGCAGCAC CAGCAGATGA TGCGCTGGCT GAAGGGGGAG 
AGGCCTGGGC CCGAGGACGA GCAACCCTCA TCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ATAD3C ( NM_001039211.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034300.2 Homo sapiens ATPase family AAA domain containing 3C (ATAD3C), mRNA.

Price & Availability↑

CloneID	OHu24368
Clone ID Related Accession (Same CDS sequence)	NM_001039211.2 , NM_001039211.3
Accession Version	NM_001039211.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1236bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	ATPase family AAA domain-containing protein 3C
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL391244.11 and AL157945.21. On May 17, 2019 this sequence version replaced NM_001039211.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK091918.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2159931 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGTCAAAGG ACGCCCTGAA TCTGGCGCAG ATGCAGGAGC AGACGCTGCA GTTGGAGCAA 
CAGTCCAAGC TCAAACAACT TGTCAATGAG GATTTACGGA AGCAGGAGGA GTCCGTGCAG 
AAGCACCATC AGACCTTCTT GGAGTCCATC AGGGCGGCTG GCACCTTGTT TGGGGAAGGA 
TTCCGTGCCT TTGTGACAGA CCGGGACAAA GTGACAGCCA CGGTGGCTGG GCTGACGCTG 
CTGGCTGTCG GGGTCTACTC AGCCAAGAAT GCGACAGCCG TCACTGGCCG CTACATCGAG 
GCTCGGCTGG GGAAGCCGTC CCTAGTGAGG GAGACGTCCC GCATCACGGT GCTTGAGGCG 
CTGCGGCACC CCATCCAGCA GGTCAGCCGG CGGCTCCTCA GTCGACCCCA GGACGTGCTG 
GAGGGTGTTG TGCTTAGTCC CAGCCTGGAA GCACGGGTGC GCGACATCGC CATAATGACA 
AGGAACATCA AGAAGAACCG GGGCCTGTAC AGGCACATCC TGCTGTACGG GCCACCAGGC 
ACCGGGAAGA CGCTGTTTGC CAAGAAACTC GCCCTGCACT CAGGCATGGA CTACGCCATC 
ATGACAGGCG GGGACGTGGC CCCCATGGGG CGGGAAGGCG TGACCGCCAT GCACAAGCTC 
TTTGACTGGG CCAATACCAG CCGGCGCGGC CTCCTGCTCT TTGTGGATGA AGCGGACGCC 
TTCCTTCGGA AGCGAGCCAC TGAGAAGATA AGCGAGGACC TCAGGGCCAC ACTGAACGCC 
TTCCTGTACC GCACGGGCCA GCACAGCAAC AAATTCATGC TGATCCTGGC CAGCTGCCAC 
CCCGAGCAGT TCGACTGGGC CATCAATGCC TGCATCGACG TGATGGTCCA CTTCGACCTG 
CCAGGGCAGG AGGAGCGGGC GCGCCTGGTG AGAATGTATC TTAACGAGTA TGTTCTTAAG 
CCGGCCACAG AAGGAAAGCG GCGTCTGAAG CTGGCCCAGT TTGACTACGG GAGGAAGTGC 
TTAGAGATCG CTCGGCTGAC AGAGGGCATG TCATGCCGGA AGATCGCACA GCTGGCCGTG 
TCCTGGCAGG CCACGGCGTA TGCCTCCAAG GACGGGGTCC TGACCGAGGC CATGATGGAC 
GCCTGCGTGC AAGACTTTGT CCAGCAGCAC CAGCAGATGA TGCGCTGGCT GAAGGGGGAG 
AGGCCTGGGC CCGAGGACGA GCAACCCTCA TCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034300.2
CDS	996..2231
Translation	MSKDALNLAQMQEQTLQLEQQSKLKQLVNEDLRKQEESVQKHHQTFLESIRAAGTLFGEGFRAFVTDRDKVTATVAGLTLLAVGVYSAKNATAVTGRYIEARLGKPSLVRETSRITVLEALRHPIQQVSRRLLSRPQDVLEGVVLSPSLEARVRDIAIMTRNIKKNRGLYRHILLYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKLFDWANTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLYRTGQHSNKFMLILASCHPEQFDWAINACIDVMVHFDLPGQEERARLVRMYLNEYVLKPATEGKRRLKLAQFDYGRKCLEIARLTEGMSCRKIAQLAVSWQATAYASKDGVLTEAMMDACVQDFVQQHQQMMRWLKGERPGPEDEQPSS

Target ORF information:

RefSeq Version	NM_001039211.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ATPase family AAA domain containing 3C (ATAD3C), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039211.3

ORF Insert Sequence:

ATGTCAAAGG ACGCCCTGAA TCTGGCGCAG ATGCAGGAGC AGACGCTGCA GTTGGAGCAA 
CAGTCCAAGC TCAAACAACT TGTCAATGAG GATTTACGGA AGCAGGAGGA GTCCGTGCAG 
AAGCACCATC AGACCTTCTT GGAGTCCATC AGGGCGGCTG GCACCTTGTT TGGGGAAGGA 
TTCCGTGCCT TTGTGACAGA CCGGGACAAA GTGACAGCCA CGGTGGCTGG GCTGACGCTG 
CTGGCTGTCG GGGTCTACTC AGCCAAGAAT GCGACAGCCG TCACTGGCCG CTACATCGAG 
GCTCGGCTGG GGAAGCCGTC CCTAGTGAGG GAGACGTCCC GCATCACGGT GCTTGAGGCG 
CTGCGGCACC CCATCCAGCA GGTCAGCCGG CGGCTCCTCA GTCGACCCCA GGACGTGCTG 
GAGGGTGTTG TGCTTAGTCC CAGCCTGGAA GCACGGGTGC GCGACATCGC CATAATGACA 
AGGAACATCA AGAAGAACCG GGGCCTGTAC AGGCACATCC TGCTGTACGG GCCACCAGGC 
ACCGGGAAGA CGCTGTTTGC CAAGAAACTC GCCCTGCACT CAGGCATGGA CTACGCCATC 
ATGACAGGCG GGGACGTGGC CCCCATGGGG CGGGAAGGCG TGACCGCCAT GCACAAGCTC 
TTTGACTGGG CCAATACCAG CCGGCGCGGC CTCCTGCTCT TTGTGGATGA AGCGGACGCC 
TTCCTTCGGA AGCGAGCCAC TGAGAAGATA AGCGAGGACC TCAGGGCCAC ACTGAACGCC 
TTCCTGTACC GCACGGGCCA GCACAGCAAC AAATTCATGC TGATCCTGGC CAGCTGCCAC 
CCCGAGCAGT TCGACTGGGC CATCAATGCC TGCATCGACG TGATGGTCCA CTTCGACCTG 
CCAGGGCAGG AGGAGCGGGC GCGCCTGGTG AGAATGTATC TTAACGAGTA TGTTCTTAAG 
CCGGCCACAG AAGGAAAGCG GCGTCTGAAG CTGGCCCAGT TTGACTACGG GAGGAAGTGC 
TTAGAGATCG CTCGGCTGAC AGAGGGCATG TCATGCCGGA AGATCGCACA GCTGGCCGTG 
TCCTGGCAGG CCACGGCGTA TGCCTCCAAG GACGGGGTCC TGACCGAGGC CATGATGGAC 
GCCTGCGTGC AAGACTTTGT CCAGCAGCAC CAGCAGATGA TGCGCTGGCT GAAGGGGGAG 
AGGCCTGGGC CCGAGGACGA GCAACCCTCA TCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism.
Brain : a journal of neurology140(6)1595-1610(2017 Jun)
Desai R,Frazier AE,Durigon R,Patel H,Jones AW,Dalla Rosa I,Lake NJ,Compton AG,Mountford HS,Tucker EJ,Mitchell ALR,Jackson D,Sesay A,Di Re M,van den Heuvel LP,Burke D,Francis D,Lunke S,McGillivray G,Mandelstam S,Mochel F,Keren B,Jardel C,Turner AM,Ian Andrews P,Smeitink J,Spelbrink JN,Heales SJ,Kohda M,Ohtake A,Murayama K,Okazaki Y,Lomb?s A,Holt IJ,Thorburn DR,Spinazzola A

[ATAD3, a vital membrane-bound mitochondrial ATPase involved in tumor progression].
Medecine sciences : M/S27(12)1089-95(2011 Dec)
Li S,Rousseau D