FANCG cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FANCG
Entrez Gene ID	2189
Full Name	Fanconi anemia complementation group G
Synonyms	FAG,XRCC9
General protein information	Preferred Names Fanconi anemia complementation group G Names Fanconi anemia group G protein DNA repair protein XRCC9 X-ray repair complementing defective repair in Chinese hamster cells 9 X-ray repair, complementing defective, in Chinese hamster, 9 truncated Fanconi anemia group G protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9p13.3
Summary	The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G. [provided by RefSeq, Jul 2008].
Disorder MIM:	602956
Disorder Html:	Fanconi anemia, complementation group G, 614082 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_004629.1	NP_004620.1	Fanconi anemia group G protein
NM_004629.2	NP_004620.1	Fanconi anemia group G protein

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	FANCG	XP_001165190.1
Mus musculus (house mouse)	Fancg	NP_444311.1
Rattus norvegicus (Norway rat)	Fancg	XP_006238187.1
Bos taurus (cattle)	FANCG	NP_001095757.1
Homo sapiens (human)	FANCG	NP_004620.1
Xenopus tropicalis (tropical clawed frog)	fancg	NP_001120193.1
Canis lupus familiaris (dog)	FANCG	XP_854703.1
Danio rerio (zebrafish)	fancg	NP_991202.1
	FANCG	XP_001092322.1
Gallus gallus (chicken)	FANCG	NP_989709.1

Gene Ontology
Bibliography

Related articles in PubMed

Loss of heterozygosity in FANCG, FANCF and BRIP1 from head and neck squamous cell carcinoma of the oral cavity.
T?rke C, Horn S, Petto C, Labudde D, Lauer G, Wittenburg G
International journal of oncology50(6)2207-2220(2017 Jun)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Characterization of two novel FANCG mutations in Indian Fanconi anemia patients.
Solanki A, Kumar Selvaa C, Sheth F, Radhakrishnan N, Kalra M, Vundinti BR
Leukemia research5350-56(2017 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

a systems biology approach for elucidating the therapeutic potential of curcumin against FA and leukemia is investigated by analyzing the computational molecular interactions of curcumin ligand with FANC G of FA and seven other key disease targets of leukemia
Title: A systems biology approach for elucidating the interaction of curcumin with Fanconi anemia FANC G protein and the key disease targets of leukemia.

studied the impact of mutations on the function and structure of FANCG
Title: Characterization of two novel FANCG mutations in Indian Fanconi anemia patients.

founder haplotype analysis of FANCG for the Korean Fanconi anemia population
Title: Founder haplotype analysis of Fanconi anemia in the Korean population finds common ancestral haplotypes for a FANCG variant.

A new role of FANCG in Homologous recombination repair of interstrand crosslinks through K63Ub-mediated interaction with the Rap80-BRCA1 complex.
Title: K63-linked ubiquitination of FANCG is required for its association with the Rap80-BRCA1 complex to modulate homologous recombination repair of DNA interstand crosslinks.

Patients, homozygous for the FANCG founder mutation, present with severe cytopenia but progress to bone marrow failure at similar ages to other individuals affected with Fanconi anemia of heterogeneous genotype.
Title: Hematological consequences of a FANCG founder mutation in Black South African patients with Fanconi anemia.

The following FANCG gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FANCG cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25922	NM_004629.2 Latest version!	Homo sapiens FA complementation group G (FANCG), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
View Old Accession Versions >>
OHu25922	NM_004629.1	Homo sapiens FA complementation group G (FANCG), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FANCG ( NM_004629.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_004620.1 Homo sapiens FA complementation group G (FANCG), mRNA.

Price & Availability↑

CloneID	OHu25922
Clone ID Related Accession (Same CDS sequence)	NM_004629.1 , NM_004629.2
Accession Version	NM_004629.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1869bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	Fanconi anemia group G protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ007669.1. This sequence is a reference standard in the RefSeqGene project. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ007669.1, SRR1660805.59875.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCCCGCC AGACCACCTC TGTGGGCTCC AGCTGCCTGG ACCTGTGGAG GGAAAAGAAT 
GACCGGCTCG TTCGACAGGC CAAGGTGGCT CAGAACTCCG GTCTGACTCT GAGGCGACAG 
CAGTTGGCTC AGGATGCACT GGAAGGGCTC AGAGGGCTCC TCCATAGTCT GCAAGGGCTC 
CCTGCAGCTG TTCCTGTTCT TCCCTTGGAG CTGACTGTCA CCTGCAACTT CATTATCCTG 
AGGGCAAGCT TGGCCCAGGG TTTCACAGAG GATCAGGCCC AGGATATCCA GCGGAGCCTA 
GAGAGAGTGC TGGAGACACA GGAGCAGCAG GGGCCCAGGT TGGAACAGGG GCTCAGGGAG 
CTGTGGGACT CTGTCCTTCG TGCTTCCTGC CTTCTGCCGG AGCTGCTGTC TGCCCTGCAC 
CGCCTGGTTG GCCTGCAGGC TGCCCTCTGG TTGAGTGCTG ACCGTCTTGG GGACCTGGCC 
TTGTTACTAG AGACCCTGAA TGGCAGCCAG AGTGGAGCCT CTAAGGATCT GCTGTTACTT 
CTGAAAACTT GGAGTCCCCC AGCTGAGGAA TTAGATGCTC CATTGACCCT GCAGGATGCC 
CAGGGATTGA AGGATGTCCT CCTGACAGCA TTTGCCTACC GCCAAGGTCT CCAGGAGCTG 
ATCACAGGGA ACCCAGACAA GGCACTAAGC AGCCTTCATG AAGCGGCCTC AGGCCTGTGT 
CCACGGCCTG TGTTGGTCCA GGTGTACACA GCACTGGGGT CCTGTCACCG TAAGATGGGA 
AATCCACAGA GAGCACTGTT GTACTTGGTT GCAGCCCTGA AAGAGGGATC AGCCTGGGGT 
CCTCCACTTC TGGAGGCCTC TAGGCTCTAT CAGCAACTGG GGGACACAAC AGCAGAGCTG 
GAGAGTCTGG AGCTGCTAGT TGAGGCCTTG AATGTCCCAT GCAGTTCCAA AGCCCCGCAG 
TTTCTCATTG AGGTAGAATT ACTACTGCCA CCACCTGACC TAGCCTCACC CCTTCATTGT 
GGCACTCAGA GCCAGACCAA GCACATACTA GCAAGCAGGT GCCTACAGAC GGGGAGGGCA 
GGAGACGCTG CAGAGCATTA CTTGGACCTG CTGGCCCTGT TGCTGGATAG CTCGGAGCCA 
AGGTTCTCCC CACCCCCCTC CCCTCCAGGG CCCTGTATGC CTGAGGTGTT TTTGGAGGCA 
GCGGTAGCAC TGATCCAGGC AGGCAGAGCC CAAGATGCCT TGACTCTATG TGAGGAGTTG 
CTCAGCCGCA CATCATCTCT GCTACCCAAG ATGTCCCGGC TGTGGGAAGA TGCCAGAAAA 
GGAACCAAGG AACTGCCATA CTGCCCACTC TGGGTCTCTG CCACCCACCT GCTTCAGGGC 
CAGGCCTGGG TTCAACTGGG TGCCCAAAAA GTGGCAATTA GTGAATTTAG CAGGTGCCTC 
GAGCTGCTCT TCCGGGCCAC ACCTGAGGAA AAAGAACAAG GGGCAGCTTT CAACTGTGAG 
CAGGGATGTA AGTCAGATGC GGCACTGCAG CAGCTTCGGG CAGCCGCCCT AATTAGTCGT 
GGACTGGAAT GGGTAGCCAG CGGCCAGGAT ACCAAAGCCT TACAGGACTT CCTCCTCAGT 
GTGCAGATGT GCCCAGGTAA TCGAGACACT TACTTTCACC TGCTTCAGAC TCTGAAGAGG 
CTAGATCGGA GGGATGAGGC CACTGCACTC TGGTGGAGGC TGGAGGCCCA AACTAAGGGG 
TCACATGAAG ATGCTCTGTG GTCTCTCCCC CTGTACCTAG AAAGCTATTT GAGCTGGATC 
CGTCCCTCTG ATCGTGACGC CTTCCTTGAA GAATTTCGGA CATCTCTGCC AAAGTCTTGT 
GACCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004620.1
CDS	493..2361
Translation	MSRQTTSVGSSCLDLWREKNDRLVRQAKVAQNSGLTLRRQQLAQDALEGLRGLLHSLQGLPAAVPVLPLELTVTCNFIILRASLAQGFTEDQAQDIQRSLERVLETQEQQGPRLEQGLRELWDSVLRASCLLPELLSALHRLVGLQAALWLSADRLGDLALLLETLNGSQSGASKDLLLLLKTWSPPAEELDAPLTLQDAQGLKDVLLTAFAYRQGLQELITGNPDKALSSLHEAASGLCPRPVLVQVYTALGSCHRKMGNPQRALLYLVAALKEGSAWGPPLLEASRLYQQLGDTTAELESLELLVEALNVPCSSKAPQFLIEVELLLPPPDLASPLHCGTQSQTKHILASRCLQTGRAGDAAEHYLDLLALLLDSSEPRFSPPPSPPGPCMPEVFLEAAVALIQAGRAQDALTLCEELLSRTSSLLPKMSRLWEDARKGTKELPYCPLWVSATHLLQGQAWVQLGAQKVAISEFSRCLELLFRATPEEKEQGAAFNCEQGCKSDAALQQLRAAALISRGLEWVASGQDTKALQDFLLSVQMCPGNRDTYFHLLQTLKRLDRRDEATALWWRLEAQTKGSHEDALWSLPLYLESYLSWIRPSDRDAFLEEFRTSLPKSCDL

Target ORF information:

RefSeq Version	NM_004629.1
Organism	Homo sapiens(human)
Definition	Homo sapiens FA complementation group G (FANCG), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004629.1

ORF Insert Sequence:

ATGTCCCGCC AGACCACCTC TGTGGGCTCC AGCTGCCTGG ACCTGTGGAG GGAAAAGAAT 
GACCGGCTCG TTCGACAGGC CAAGGTGGCT CAGAACTCCG GTCTGACTCT GAGGCGACAG 
CAGTTGGCTC AGGATGCACT GGAAGGGCTC AGAGGGCTCC TCCATAGTCT GCAAGGGCTC 
CCTGCAGCTG TTCCTGTTCT TCCCTTGGAG CTGACTGTCA CCTGCAACTT CATTATCCTG 
AGGGCAAGCT TGGCCCAGGG TTTCACAGAG GATCAGGCCC AGGATATCCA GCGGAGCCTA 
GAGAGAGTGC TGGAGACACA GGAGCAGCAG GGGCCCAGGT TGGAACAGGG GCTCAGGGAG 
CTGTGGGACT CTGTCCTTCG TGCTTCCTGC CTTCTGCCGG AGCTGCTGTC TGCCCTGCAC 
CGCCTGGTTG GCCTGCAGGC TGCCCTCTGG TTGAGTGCTG ACCGTCTTGG GGACCTGGCC 
TTGTTACTAG AGACCCTGAA TGGCAGCCAG AGTGGAGCCT CTAAGGATCT GCTGTTACTT 
CTGAAAACTT GGAGTCCCCC AGCTGAGGAA TTAGATGCTC CATTGACCCT GCAGGATGCC 
CAGGGATTGA AGGATGTCCT CCTGACAGCA TTTGCCTACC GCCAAGGTCT CCAGGAGCTG 
ATCACAGGGA ACCCAGACAA GGCACTAAGC AGCCTTCATG AAGCGGCCTC AGGCCTGTGT 
CCACGGCCTG TGTTGGTCCA GGTGTACACA GCACTGGGGT CCTGTCACCG TAAGATGGGA 
AATCCACAGA GAGCACTGTT GTACTTGGTT GCAGCCCTGA AAGAGGGATC AGCCTGGGGT 
CCTCCACTTC TGGAGGCCTC TAGGCTCTAT CAGCAACTGG GGGACACAAC AGCAGAGCTG 
GAGAGTCTGG AGCTGCTAGT TGAGGCCTTG AATGTCCCAT GCAGTTCCAA AGCCCCGCAG 
TTTCTCATTG AGGTAGAATT ACTACTGCCA CCACCTGACC TAGCCTCACC CCTTCATTGT 
GGCACTCAGA GCCAGACCAA GCACATACTA GCAAGCAGGT GCCTACAGAC GGGGAGGGCA 
GGAGACGCTG CAGAGCATTA CTTGGACCTG CTGGCCCTGT TGCTGGATAG CTCGGAGCCA 
AGGTTCTCCC CACCCCCCTC CCCTCCAGGG CCCTGTATGC CTGAGGTGTT TTTGGAGGCA 
GCGGTAGCAC TGATCCAGGC AGGCAGAGCC CAAGATGCCT TGACTCTATG TGAGGAGTTG 
CTCAGCCGCA CATCATCTCT GCTACCCAAG ATGTCCCGGC TGTGGGAAGA TGCCAGAAAA 
GGAACCAAGG AACTGCCATA CTGCCCACTC TGGGTCTCTG CCACCCACCT GCTTCAGGGC 
CAGGCCTGGG TTCAACTGGG TGCCCAAAAA GTGGCAATTA GTGAATTTAG CAGGTGCCTC 
GAGCTGCTCT TCCGGGCCAC ACCTGAGGAA AAAGAACAAG GGGCAGCTTT CAACTGTGAG 
CAGGGATGTA AGTCAGATGC GGCACTGCAG CAGCTTCGGG CAGCCGCCCT AATTAGTCGT 
GGACTGGAAT GGGTAGCCAG CGGCCAGGAT ACCAAAGCCT TACAGGACTT CCTCCTCAGT 
GTGCAGATGT GCCCAGGTAA TCGAGACACT TACTTTCACC TGCTTCAGAC TCTGAAGAGG 
CTAGATCGGA GGGATGAGGC CACTGCACTC TGGTGGAGGC TGGAGGCCCA AACTAAGGGG 
TCACATGAAG ATGCTCTGTG GTCTCTCCCC CTGTACCTAG AAAGCTATTT GAGCTGGATC 
CGTCCCTCTG ATCGTGACGC CTTCCTTGAA GAATTTCGGA CATCTCTGCC AAAGTCTTGT 
GACCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FANCG ( NM_004629.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_004620.1 Homo sapiens FA complementation group G (FANCG), mRNA.

Price & Availability↑

CloneID	OHu25922
Clone ID Related Accession (Same CDS sequence)	NM_004629.1 , NM_004629.2
Accession Version	NM_004629.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1869bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	Fanconi anemia group G protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ007669.1. On Dec 4, 2019 this sequence version replaced NM_004629.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC011623.2, U70310.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCCCGCC AGACCACCTC TGTGGGCTCC AGCTGCCTGG ACCTGTGGAG GGAAAAGAAT 
GACCGGCTCG TTCGACAGGC CAAGGTGGCT CAGAACTCCG GTCTGACTCT GAGGCGACAG 
CAGTTGGCTC AGGATGCACT GGAAGGGCTC AGAGGGCTCC TCCATAGTCT GCAAGGGCTC 
CCTGCAGCTG TTCCTGTTCT TCCCTTGGAG CTGACTGTCA CCTGCAACTT CATTATCCTG 
AGGGCAAGCT TGGCCCAGGG TTTCACAGAG GATCAGGCCC AGGATATCCA GCGGAGCCTA 
GAGAGAGTGC TGGAGACACA GGAGCAGCAG GGGCCCAGGT TGGAACAGGG GCTCAGGGAG 
CTGTGGGACT CTGTCCTTCG TGCTTCCTGC CTTCTGCCGG AGCTGCTGTC TGCCCTGCAC 
CGCCTGGTTG GCCTGCAGGC TGCCCTCTGG TTGAGTGCTG ACCGTCTTGG GGACCTGGCC 
TTGTTACTAG AGACCCTGAA TGGCAGCCAG AGTGGAGCCT CTAAGGATCT GCTGTTACTT 
CTGAAAACTT GGAGTCCCCC AGCTGAGGAA TTAGATGCTC CATTGACCCT GCAGGATGCC 
CAGGGATTGA AGGATGTCCT CCTGACAGCA TTTGCCTACC GCCAAGGTCT CCAGGAGCTG 
ATCACAGGGA ACCCAGACAA GGCACTAAGC AGCCTTCATG AAGCGGCCTC AGGCCTGTGT 
CCACGGCCTG TGTTGGTCCA GGTGTACACA GCACTGGGGT CCTGTCACCG TAAGATGGGA 
AATCCACAGA GAGCACTGTT GTACTTGGTT GCAGCCCTGA AAGAGGGATC AGCCTGGGGT 
CCTCCACTTC TGGAGGCCTC TAGGCTCTAT CAGCAACTGG GGGACACAAC AGCAGAGCTG 
GAGAGTCTGG AGCTGCTAGT TGAGGCCTTG AATGTCCCAT GCAGTTCCAA AGCCCCGCAG 
TTTCTCATTG AGGTAGAATT ACTACTGCCA CCACCTGACC TAGCCTCACC CCTTCATTGT 
GGCACTCAGA GCCAGACCAA GCACATACTA GCAAGCAGGT GCCTACAGAC GGGGAGGGCA 
GGAGACGCTG CAGAGCATTA CTTGGACCTG CTGGCCCTGT TGCTGGATAG CTCGGAGCCA 
AGGTTCTCCC CACCCCCCTC CCCTCCAGGG CCCTGTATGC CTGAGGTGTT TTTGGAGGCA 
GCGGTAGCAC TGATCCAGGC AGGCAGAGCC CAAGATGCCT TGACTCTATG TGAGGAGTTG 
CTCAGCCGCA CATCATCTCT GCTACCCAAG ATGTCCCGGC TGTGGGAAGA TGCCAGAAAA 
GGAACCAAGG AACTGCCATA CTGCCCACTC TGGGTCTCTG CCACCCACCT GCTTCAGGGC 
CAGGCCTGGG TTCAACTGGG TGCCCAAAAA GTGGCAATTA GTGAATTTAG CAGGTGCCTC 
GAGCTGCTCT TCCGGGCCAC ACCTGAGGAA AAAGAACAAG GGGCAGCTTT CAACTGTGAG 
CAGGGATGTA AGTCAGATGC GGCACTGCAG CAGCTTCGGG CAGCCGCCCT AATTAGTCGT 
GGACTGGAAT GGGTAGCCAG CGGCCAGGAT ACCAAAGCCT TACAGGACTT CCTCCTCAGT 
GTGCAGATGT GCCCAGGTAA TCGAGACACT TACTTTCACC TGCTTCAGAC TCTGAAGAGG 
CTAGATCGGA GGGATGAGGC CACTGCACTC TGGTGGAGGC TGGAGGCCCA AACTAAGGGG 
TCACATGAAG ATGCTCTGTG GTCTCTCCCC CTGTACCTAG AAAGCTATTT GAGCTGGATC 
CGTCCCTCTG ATCGTGACGC CTTCCTTGAA GAATTTCGGA CATCTCTGCC AAAGTCTTGT 
GACCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004620.1
CDS	419..2287
Translation	MSRQTTSVGSSCLDLWREKNDRLVRQAKVAQNSGLTLRRQQLAQDALEGLRGLLHSLQGLPAAVPVLPLELTVTCNFIILRASLAQGFTEDQAQDIQRSLERVLETQEQQGPRLEQGLRELWDSVLRASCLLPELLSALHRLVGLQAALWLSADRLGDLALLLETLNGSQSGASKDLLLLLKTWSPPAEELDAPLTLQDAQGLKDVLLTAFAYRQGLQELITGNPDKALSSLHEAASGLCPRPVLVQVYTALGSCHRKMGNPQRALLYLVAALKEGSAWGPPLLEASRLYQQLGDTTAELESLELLVEALNVPCSSKAPQFLIEVELLLPPPDLASPLHCGTQSQTKHILASRCLQTGRAGDAAEHYLDLLALLLDSSEPRFSPPPSPPGPCMPEVFLEAAVALIQAGRAQDALTLCEELLSRTSSLLPKMSRLWEDARKGTKELPYCPLWVSATHLLQGQAWVQLGAQKVAISEFSRCLELLFRATPEEKEQGAAFNCEQGCKSDAALQQLRAAALISRGLEWVASGQDTKALQDFLLSVQMCPGNRDTYFHLLQTLKRLDRRDEATALWWRLEAQTKGSHEDALWSLPLYLESYLSWIRPSDRDAFLEEFRTSLPKSCDL

Target ORF information:

RefSeq Version	NM_004629.2
Organism	Homo sapiens(human)
Definition	Homo sapiens FA complementation group G (FANCG), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004629.2

ORF Insert Sequence:

ATGTCCCGCC AGACCACCTC TGTGGGCTCC AGCTGCCTGG ACCTGTGGAG GGAAAAGAAT 
GACCGGCTCG TTCGACAGGC CAAGGTGGCT CAGAACTCCG GTCTGACTCT GAGGCGACAG 
CAGTTGGCTC AGGATGCACT GGAAGGGCTC AGAGGGCTCC TCCATAGTCT GCAAGGGCTC 
CCTGCAGCTG TTCCTGTTCT TCCCTTGGAG CTGACTGTCA CCTGCAACTT CATTATCCTG 
AGGGCAAGCT TGGCCCAGGG TTTCACAGAG GATCAGGCCC AGGATATCCA GCGGAGCCTA 
GAGAGAGTGC TGGAGACACA GGAGCAGCAG GGGCCCAGGT TGGAACAGGG GCTCAGGGAG 
CTGTGGGACT CTGTCCTTCG TGCTTCCTGC CTTCTGCCGG AGCTGCTGTC TGCCCTGCAC 
CGCCTGGTTG GCCTGCAGGC TGCCCTCTGG TTGAGTGCTG ACCGTCTTGG GGACCTGGCC 
TTGTTACTAG AGACCCTGAA TGGCAGCCAG AGTGGAGCCT CTAAGGATCT GCTGTTACTT 
CTGAAAACTT GGAGTCCCCC AGCTGAGGAA TTAGATGCTC CATTGACCCT GCAGGATGCC 
CAGGGATTGA AGGATGTCCT CCTGACAGCA TTTGCCTACC GCCAAGGTCT CCAGGAGCTG 
ATCACAGGGA ACCCAGACAA GGCACTAAGC AGCCTTCATG AAGCGGCCTC AGGCCTGTGT 
CCACGGCCTG TGTTGGTCCA GGTGTACACA GCACTGGGGT CCTGTCACCG TAAGATGGGA 
AATCCACAGA GAGCACTGTT GTACTTGGTT GCAGCCCTGA AAGAGGGATC AGCCTGGGGT 
CCTCCACTTC TGGAGGCCTC TAGGCTCTAT CAGCAACTGG GGGACACAAC AGCAGAGCTG 
GAGAGTCTGG AGCTGCTAGT TGAGGCCTTG AATGTCCCAT GCAGTTCCAA AGCCCCGCAG 
TTTCTCATTG AGGTAGAATT ACTACTGCCA CCACCTGACC TAGCCTCACC CCTTCATTGT 
GGCACTCAGA GCCAGACCAA GCACATACTA GCAAGCAGGT GCCTACAGAC GGGGAGGGCA 
GGAGACGCTG CAGAGCATTA CTTGGACCTG CTGGCCCTGT TGCTGGATAG CTCGGAGCCA 
AGGTTCTCCC CACCCCCCTC CCCTCCAGGG CCCTGTATGC CTGAGGTGTT TTTGGAGGCA 
GCGGTAGCAC TGATCCAGGC AGGCAGAGCC CAAGATGCCT TGACTCTATG TGAGGAGTTG 
CTCAGCCGCA CATCATCTCT GCTACCCAAG ATGTCCCGGC TGTGGGAAGA TGCCAGAAAA 
GGAACCAAGG AACTGCCATA CTGCCCACTC TGGGTCTCTG CCACCCACCT GCTTCAGGGC 
CAGGCCTGGG TTCAACTGGG TGCCCAAAAA GTGGCAATTA GTGAATTTAG CAGGTGCCTC 
GAGCTGCTCT TCCGGGCCAC ACCTGAGGAA AAAGAACAAG GGGCAGCTTT CAACTGTGAG 
CAGGGATGTA AGTCAGATGC GGCACTGCAG CAGCTTCGGG CAGCCGCCCT AATTAGTCGT 
GGACTGGAAT GGGTAGCCAG CGGCCAGGAT ACCAAAGCCT TACAGGACTT CCTCCTCAGT 
GTGCAGATGT GCCCAGGTAA TCGAGACACT TACTTTCACC TGCTTCAGAC TCTGAAGAGG 
CTAGATCGGA GGGATGAGGC CACTGCACTC TGGTGGAGGC TGGAGGCCCA AACTAAGGGG 
TCACATGAAG ATGCTCTGTG GTCTCTCCCC CTGTACCTAG AAAGCTATTT GAGCTGGATC 
CGTCCCTCTG ATCGTGACGC CTTCCTTGAA GAATTTCGGA CATCTCTGCC AAAGTCTTGT 
GACCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Loss of heterozygosity in FANCG, FANCF and BRIP1 from head and neck squamous cell carcinoma of the oral cavity.
International journal of oncology50(6)2207-2220(2017 Jun)
T?rke C,Horn S,Petto C,Labudde D,Lauer G,Wittenburg G

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Characterization of two novel FANCG mutations in Indian Fanconi anemia patients.
Leukemia research5350-56(2017 Feb)
Solanki A,Kumar Selvaa C,Sheth F,Radhakrishnan N,Kalra M,Vundinti BR

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FANCG cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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