FANCE cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FANCE
Entrez Gene ID	2178
Full Name	Fanconi anemia complementation group E
Synonyms	FACE,FAE
General protein information	Preferred Names Fanconi anemia complementation group E Names Fanconi anemia group E protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p21.31
Summary	The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group E. [provided by RefSeq, Jul 2008].
Disorder MIM:	613976
Disorder Html:	Fanconi anemia, complementation group E, 600901 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005248885.2	XP_005248942.1	Fanconi anemia group E protein isoform X1
XM_005248886.2	XP_005248943.1	Fanconi anemia group E protein isoform X2
XM_011514343.2	XP_011512645.1	Fanconi anemia group E protein isoform X5
NM_021922.3	NP_068741.1	Fanconi anemia group E protein
XM_005248887.2	XP_005248944.1	Fanconi anemia group E protein isoform X3
NM_021922.2	NP_068741.1	Fanconi anemia group E protein
XM_005248888.3	XP_005248945.1	Fanconi anemia group E protein isoform X4

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	FANCE	XP_003639456.1
Bos taurus (cattle)	FANCE	NP_001179278.1
Rattus norvegicus (Norway rat)	Fance	NP_001178647.1
Gallus gallus (chicken)	FANCE	XP_004935067.1
	FANCE	XP_001116683.1
Danio rerio (zebrafish)	fance	NP_001035724.1
Xenopus tropicalis (tropical clawed frog)	fance	XP_002941449.1
Homo sapiens (human)	FANCE	NP_068741.1
Pan troglodytes (chimpanzee)	FANCE	XP_001172322.2
Mus musculus (house mouse)	Fance	NP_001157291.1

Gene Ontology
Bibliography

Related articles in PubMed

Analysis of a FANCE Splice Isoform in Regard to DNA Repair.
Bouffard F, Plourde K, B?langer S, Ouellette G, Labrie Y, Durocher F
Journal of molecular biology427(19)3056-73(2015 Sep)

The carboxyl terminus of FANCE recruits FANCD2 to the Fanconi Anemia (FA) E3 ligase complex to promote the FA DNA repair pathway.
Polito D, Cukras S, Wang X, Spence P, Moreau L, D'Andrea AD, Kee Y
The Journal of biological chemistry289(10)7003-10(2014 Mar)

Regulation of Rev1 by the Fanconi anemia core complex.
Kim H, Yang K, Dejsuphong D, D'Andrea AD
Nature structural & molecular biology19(2)164-70(2012 Jan)

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
Hancock DB, Soler Artigas M, Gharib SA, Henry A, Manichaikul A, Ramasamy A, Loth DW, Imboden M, Koch B, McArdle WL, Smith AV, Smolonska J, Sood A, Tang W, Wilk JB, Zhai G, Zhao JH, Aschard H, Burkart KM, Curjuric I, Eijgelsheim M, Elliott P, Gu X, Harris TB, Janson C, Homuth G, Hysi PG, Liu JZ, Loehr LR, Lohman K, Loos RJ, Manning AK, Marciante KD, Obeidat M, Postma DS, Aldrich MC, Brusselle GG, Chen TH, Eiriksdottir G, Franceschini N, Heinrich J, Rotter JI, Wijmenga C, Williams OD, Bentley AR, Hofman A, Laurie CC, Lumley T, Morrison AC, Joubert BR, Rivadeneira F, Couper DJ, Kritchevsky SB, Liu Y, Wjst M, Wain LV, Vonk JM, Uitterlinden AG, Rochat T, Rich SS, Psaty BM, O'Connor GT, North KE, Mirel DB, Meibohm B, Launer LJ, Khaw KT, Hartikainen AL, Hammond CJ, Gl?ser S, Marchini J, Kraft P, Wareham NJ, V?lzke H, Stricker BH, Spector TD, Probst-Hensch NM, Jarvis D, Jarvelin MR, Heckbert SR, Gudnason V, Boezen HM, Barr RG, Cassano PA, Strachan DP, Fornage M, Hall IP, Dupuis J, Tobin MD, London SJ
PLoS genetics8(12)e1003098(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

A novel alternative splicing event of the FANCE gene has been characterized. FANCEDelta4 cannot support the activation of the FANC-BRCA pathway and DNA repair.
Title: Analysis of a FANCE Splice Isoform in Regard to DNA Repair.

a phenylalanine located at the highly conserved extreme C terminus, referred to as Phe-522, is a critical residue for mediating the monoubiquitination of the FANCD2-FANCI complex.
Title: The carboxyl terminus of FANCE recruits FANCD2 to the Fanconi Anemia (FA) E3 ligase complex to promote the FA DNA repair pathway.

Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
Title: Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk.

Observational study of gene-disease association. (HuGE Navigator)
Title: Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.

Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
Title: Genetic variation in genes interacting with BRCA1/2 and risk of breast cancer in the Cypriot population.

The following FANCE gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FANCE cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu57681	XM_011514343.2 Latest version!	Homo sapiens FA complementation group E (FANCE), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu21011	NM_021922.3 Latest version!	Homo sapiens FA complementation group E (FANCE), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu40178	XM_005248885.2 Latest version!	Homo sapiens FA complementation group E (FANCE), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu40179	XM_005248886.2 Latest version!	Homo sapiens FA complementation group E (FANCE), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu40180	XM_005248887.2 Latest version!	Homo sapiens FA complementation group E (FANCE), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu40181	XM_005248888.3 Latest version!	Homo sapiens FA complementation group E (FANCE), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
View Old Accession Versions >>
OHu21011	NM_021922.2	Homo sapiens FA complementation group E (FANCE), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FANCE ( NM_021922.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_068741.1 Homo sapiens FA complementation group E (FANCE), mRNA.

Price & Availability↑

CloneID	OHu21011
Clone ID Related Accession (Same CDS sequence)	NM_021922.3 , NM_021922.2
Accession Version	NM_021922.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1611bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	Fanconi anemia group E protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF265210.1 and AL022721.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2005 this sequence version replaced NM_021922.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF265210.1, BC046359.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGACAC CGGACGCGGG GCTCCCTGGG GCTGAGGGCG TGGAGCCGGC GCCCTGGGCG 
CAGCTGGAGG CCCCCGCCCG CCTCCTGCTG CAGGCGCTGC AGGCGGGGCC TGAGGGGGCG 
CGGCGCGGCC TGGGGGTGCT CCGGGCGCTG GGCAGCCGCG GCTGGGAGCC CTTCGACTGG 
GGTCGCTTGC TCGAGGCCCT GTGCCGGGAG GAGCCGGTCG TGCAGGGGCC TGACGGCCGT 
CTGGAGCTGA AACCACTGTT GCTGCGATTG CCCCGGATAT GCCAGAGGAA CCTGATGTCC 
CTGCTGATGG CCGTTCGGCC ATCGCTGCCG GAAAGTGGGC TCCTCTCTGT GCTGCAGATT 
GCCCAGCAGG ACCTAGCCCC TGACCCAGAT GCCTGGCTCC GTGCCCTGGG GGAATTGCTG 
CGAAGGGATT TGGGGGTGGG GACCTCCATG GAGGGAGCTT CTCCACTGTC TGAAAGATGC 
CAGAGACAGC TCCAAAGTCT ATGTAGGGGG CTGGGCCTGG GGGGCAGGAG GTTGAAATCC 
CCCCAGGCTC CAGACCCTGA AGAAGAGGAG AACAGGGACT CCCAGCAGCC TGGGAAACGC 
AGAAAGGACT CAGAGGAAGA GGCTGCCAGT CCTGAGGGGA AGAGGGTCCC CAAAAGATTA 
CGGTGTTGGG AAGAGGAAGA AGATCATGAG AAGGAGAGAC CCGAACATAA GTCACTGGAA 
TCCCTGGCAG ATGGAGGAAG TGCATCTCCT ATTAAGGACC AGCCTGTCAT GGCAGTTAAG 
ACTGGCGAGG ACGGTTCGAA TCTGGATGAT GCTAAAGGTC TGGCTGAGAG TTTGGAGTTG 
CCCAAAGCTA TCCAGGACCA GCTTCCCAGG CTGCAGCAGC TGCTGAAGAC CTTGGAGGAG 
GGGTTAGAGG GATTGGAGGA TGCCCCCCCA GTTGAGCTAC AGCTTCTTCA CGAATGTAGT 
CCCAGCCAGA TGGACTTGCT GTGTGCCCAG CTGCAGCTCC CTCAGCTCTC AGACCTCGGT 
CTCCTGCGGC TCTGCACCTG GCTGCTGGCC CTTTCACCTG ATCTCAGCCT CAGCAATGCT 
ACTGTGCTGA CCAGAAGCCT CTTTCTTGGA CGGATCCTCT CCTTGACTTC CTCAGCCTCC 
CGCCTGCTTA CAACTGCCCT GACCTCCTTC TGTGCCAAAT ATACATACCC TGTCTGCAGC 
GCCCTCCTTG ACCCTGTGCT CCAGGCCCCA GGCACAGGTC CTGCTCAAAC AGAGTTACTG 
TGTTGCCTTG TGAAGATGGA GTCCCTGGAG CCAGATGCAC AGGTTCTAAT GCTGGGACAG 
ATCTTGGAGC TGCCCTGGAA GGAGGAAACT TTCTTGGTGT TGCAGTCACT CCTAGAGCGG 
CAGGTGGAGA TGACCCCTGA GAAGTTCAGT GTCTTAATGG AGAAGCTCTG TAAAAAGGGG 
CTGGCAGCCA CCACCTCCAT GGCCTATGCC AAGCTCATGC TGACAGTGAT GACCAAGTAT 
CAGGCTAACA TCACTGAGAC CCAGAGGCTG GGCCTGGCTA TGGCCCTAGA ACCTAACACC 
ACCTTCCTGA GGAAGTCCCT GAAGGCCGCC TTGAAACATT TGGGCCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068741.1
CDS	186..1796
Translation	MATPDAGLPGAEGVEPAPWAQLEAPARLLLQALQAGPEGARRGLGVLRALGSRGWEPFDWGRLLEALCREEPVVQGPDGRLELKPLLLRLPRICQRNLMSLLMAVRPSLPESGLLSVLQIAQQDLAPDPDAWLRALGELLRRDLGVGTSMEGASPLSERCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLESLADGGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQLLKTLEEGLEGLEDAPPVELQLLHECSPSQMDLLCAQLQLPQLSDLGLLRLCTWLLALSPDLSLSNATVLTRSLFLGRILSLTSSASRLLTTALTSFCAKYTYPVCSALLDPVLQAPGTGPAQTELLCCLVKMESLEPDAQVLMLGQILELPWKEETFLVLQSLLERQVEMTPEKFSVLMEKLCKKGLAATTSMAYAKLMLTVMTKYQANITETQRLGLAMALEPNTTFLRKSLKAALKHLGP

Target ORF information:

RefSeq Version	NM_021922.2
Organism	Homo sapiens(human)
Definition	Homo sapiens FA complementation group E (FANCE), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021922.2

ORF Insert Sequence:

ATGGCGACAC CGGACGCGGG GCTCCCTGGG GCTGAGGGCG TGGAGCCGGC GCCCTGGGCG 
CAGCTGGAGG CCCCCGCCCG CCTCCTGCTG CAGGCGCTGC AGGCGGGGCC TGAGGGGGCG 
CGGCGCGGCC TGGGGGTGCT CCGGGCGCTG GGCAGCCGCG GCTGGGAGCC CTTCGACTGG 
GGTCGCTTGC TCGAGGCCCT GTGCCGGGAG GAGCCGGTCG TGCAGGGGCC TGACGGCCGT 
CTGGAGCTGA AACCACTGTT GCTGCGATTG CCCCGGATAT GCCAGAGGAA CCTGATGTCC 
CTGCTGATGG CCGTTCGGCC ATCGCTGCCG GAAAGTGGGC TCCTCTCTGT GCTGCAGATT 
GCCCAGCAGG ACCTAGCCCC TGACCCAGAT GCCTGGCTCC GTGCCCTGGG GGAATTGCTG 
CGAAGGGATT TGGGGGTGGG GACCTCCATG GAGGGAGCTT CTCCACTGTC TGAAAGATGC 
CAGAGACAGC TCCAAAGTCT ATGTAGGGGG CTGGGCCTGG GGGGCAGGAG GTTGAAATCC 
CCCCAGGCTC CAGACCCTGA AGAAGAGGAG AACAGGGACT CCCAGCAGCC TGGGAAACGC 
AGAAAGGACT CAGAGGAAGA GGCTGCCAGT CCTGAGGGGA AGAGGGTCCC CAAAAGATTA 
CGGTGTTGGG AAGAGGAAGA AGATCATGAG AAGGAGAGAC CCGAACATAA GTCACTGGAA 
TCCCTGGCAG ATGGAGGAAG TGCATCTCCT ATTAAGGACC AGCCTGTCAT GGCAGTTAAG 
ACTGGCGAGG ACGGTTCGAA TCTGGATGAT GCTAAAGGTC TGGCTGAGAG TTTGGAGTTG 
CCCAAAGCTA TCCAGGACCA GCTTCCCAGG CTGCAGCAGC TGCTGAAGAC CTTGGAGGAG 
GGGTTAGAGG GATTGGAGGA TGCCCCCCCA GTTGAGCTAC AGCTTCTTCA CGAATGTAGT 
CCCAGCCAGA TGGACTTGCT GTGTGCCCAG CTGCAGCTCC CTCAGCTCTC AGACCTCGGT 
CTCCTGCGGC TCTGCACCTG GCTGCTGGCC CTTTCACCTG ATCTCAGCCT CAGCAATGCT 
ACTGTGCTGA CCAGAAGCCT CTTTCTTGGA CGGATCCTCT CCTTGACTTC CTCAGCCTCC 
CGCCTGCTTA CAACTGCCCT GACCTCCTTC TGTGCCAAAT ATACATACCC TGTCTGCAGC 
GCCCTCCTTG ACCCTGTGCT CCAGGCCCCA GGCACAGGTC CTGCTCAAAC AGAGTTACTG 
TGTTGCCTTG TGAAGATGGA GTCCCTGGAG CCAGATGCAC AGGTTCTAAT GCTGGGACAG 
ATCTTGGAGC TGCCCTGGAA GGAGGAAACT TTCTTGGTGT TGCAGTCACT CCTAGAGCGG 
CAGGTGGAGA TGACCCCTGA GAAGTTCAGT GTCTTAATGG AGAAGCTCTG TAAAAAGGGG 
CTGGCAGCCA CCACCTCCAT GGCCTATGCC AAGCTCATGC TGACAGTGAT GACCAAGTAT 
CAGGCTAACA TCACTGAGAC CCAGAGGCTG GGCCTGGCTA TGGCCCTAGA ACCTAACACC 
ACCTTCCTGA GGAAGTCCCT GAAGGCCGCC TTGAAACATT TGGGCCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FANCE ( XM_011514343.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011512645.1 Homo sapiens FA complementation group E (FANCE), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OHu57681
Clone ID Related Accession (Same CDS sequence)	XM_011514343.2
Accession Version	XM_011514343.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1317bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	Fanconi anemia group E protein isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011514343.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCCTGC TGATGGCCGT TCGGCCATCG CTGCCGGAAA GTGGGCTCCT CTCTGTGCTG 
CAGATTGCCC AGCAGGACCT AGCCCCTGAC CCAGATGCCT GGCTCCGTGC CCTGGGGGAA 
TTGCTGCGAA GGGATTTGGG GGTGGGGACC TCCATGGAGG GAGCTTCTCC ACTGTCTGAA 
AGATGCCAGA GACAGCTCCA AAGTCTATGT AGGGGGCTGG GCCTGGGGGG CAGGAGGTTG 
AAATCCCCCC AGGCTCCAGA CCCTGAAGAA GAGGAGAACA GGGACTCCCA GCAGCCTGGG 
AAACGCAGAA AGGACTCAGA GGAAGAGGCT GCCAGTCCTG AGGGGAAGAG GGTCCCCAAA 
AGATTACGGT GTTGGGAAGA GGAAGAAGAT CATGAGAAGG AGAGACCCGA ACATAAGTCA 
CTGGAATCCC TGGCAGATGG AGGAAGTGCA TCTCCTATTA AGGACCAGCC TGTCATGGCA 
GTTAAGACTG GCGAGGACGG TTCGAATCTG GATGATGCTA AAGGTCTGGC TGAGAGTTTG 
GAGTTGCCCA AAGCTATCCA GGACCAGCTT CCCAGGCTGC AGCAGCTGCT GAAGACCTTG 
GAGGAGGGGT TAGAGGGATT GGAGGATGCC CCCCCAGTTG AGCTACAGCT TCTTCACGAA 
TGTAGTCCCA GCCAGATGGA CTTGCTGTGT GCCCAGCTGC AGCTCCCTCA GCTCTCAGAC 
CTCGGTCTCC TGCGGCTCTG CACCTGGCTG CTGGCCCTTT CACCTGATCT CAGCCTCAGC 
AATGCTACTG TGCTGACCAG AAGCCTCTTT CTTGGACGGA TCCTCTCCTT GACTTCCTCA 
GCCTCCCGCC TGCTTACAAC TGCCCTGACC TCCTTCTGTG CCAAATATAC ATACCCTGTC 
TGCAGCGCCC TCCTTGACCC TGTGCTCCAG GCCCCAGGCA CAGGTCCTGC TCAAACAGAG 
TTACTGTGTT GCCTTGTGAA GATGGAGTCC CTGGAGCCAG ATGCACAGGT TCTAATGCTG 
GGACAGATCT TGGAGCTGCC CTGGAAGGAG GAAACTTTCT TGGTGTTGCA GTCACTCCTA 
GAGCGGCAGG TGGAGATGAC CCCTGAGAAG TTCAGTGTCT TAATGGAGAA GCTCTGTAAA 
AAGGGGCTGG CAGCCACCAC CTCCATGGCC TATGCCAAGC TCATGCTGAC AGTGATGACC 
AAGTATCAGG CTAACATCAC TGAGACCCAG AGGCTGGGCC TGGCTATGGC CCTAGAACCT 
AACACCACCT TCCTGAGGAA GTCCCTGAAG GCCGCCTTGA AACATTTGGG CCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011512645.1
CDS	195..1511
Translation	MSLLMAVRPSLPESGLLSVLQIAQQDLAPDPDAWLRALGELLRRDLGVGTSMEGASPLSERCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLESLADGGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQLLKTLEEGLEGLEDAPPVELQLLHECSPSQMDLLCAQLQLPQLSDLGLLRLCTWLLALSPDLSLSNATVLTRSLFLGRILSLTSSASRLLTTALTSFCAKYTYPVCSALLDPVLQAPGTGPAQTELLCCLVKMESLEPDAQVLMLGQILELPWKEETFLVLQSLLERQVEMTPEKFSVLMEKLCKKGLAATTSMAYAKLMLTVMTKYQANITETQRLGLAMALEPNTTFLRKSLKAALKHLGP

Target ORF information:

RefSeq Version	XM_011514343.2
Organism	Homo sapiens(human)
Definition	Homo sapiens FA complementation group E (FANCE), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011514343.2

ORF Insert Sequence:

ATGTCCCTGC TGATGGCCGT TCGGCCATCG CTGCCGGAAA GTGGGCTCCT CTCTGTGCTG 
CAGATTGCCC AGCAGGACCT AGCCCCTGAC CCAGATGCCT GGCTCCGTGC CCTGGGGGAA 
TTGCTGCGAA GGGATTTGGG GGTGGGGACC TCCATGGAGG GAGCTTCTCC ACTGTCTGAA 
AGATGCCAGA GACAGCTCCA AAGTCTATGT AGGGGGCTGG GCCTGGGGGG CAGGAGGTTG 
AAATCCCCCC AGGCTCCAGA CCCTGAAGAA GAGGAGAACA GGGACTCCCA GCAGCCTGGG 
AAACGCAGAA AGGACTCAGA GGAAGAGGCT GCCAGTCCTG AGGGGAAGAG GGTCCCCAAA 
AGATTACGGT GTTGGGAAGA GGAAGAAGAT CATGAGAAGG AGAGACCCGA ACATAAGTCA 
CTGGAATCCC TGGCAGATGG AGGAAGTGCA TCTCCTATTA AGGACCAGCC TGTCATGGCA 
GTTAAGACTG GCGAGGACGG TTCGAATCTG GATGATGCTA AAGGTCTGGC TGAGAGTTTG 
GAGTTGCCCA AAGCTATCCA GGACCAGCTT CCCAGGCTGC AGCAGCTGCT GAAGACCTTG 
GAGGAGGGGT TAGAGGGATT GGAGGATGCC CCCCCAGTTG AGCTACAGCT TCTTCACGAA 
TGTAGTCCCA GCCAGATGGA CTTGCTGTGT GCCCAGCTGC AGCTCCCTCA GCTCTCAGAC 
CTCGGTCTCC TGCGGCTCTG CACCTGGCTG CTGGCCCTTT CACCTGATCT CAGCCTCAGC 
AATGCTACTG TGCTGACCAG AAGCCTCTTT CTTGGACGGA TCCTCTCCTT GACTTCCTCA 
GCCTCCCGCC TGCTTACAAC TGCCCTGACC TCCTTCTGTG CCAAATATAC ATACCCTGTC 
TGCAGCGCCC TCCTTGACCC TGTGCTCCAG GCCCCAGGCA CAGGTCCTGC TCAAACAGAG 
TTACTGTGTT GCCTTGTGAA GATGGAGTCC CTGGAGCCAG ATGCACAGGT TCTAATGCTG 
GGACAGATCT TGGAGCTGCC CTGGAAGGAG GAAACTTTCT TGGTGTTGCA GTCACTCCTA 
GAGCGGCAGG TGGAGATGAC CCCTGAGAAG TTCAGTGTCT TAATGGAGAA GCTCTGTAAA 
AAGGGGCTGG CAGCCACCAC CTCCATGGCC TATGCCAAGC TCATGCTGAC AGTGATGACC 
AAGTATCAGG CTAACATCAC TGAGACCCAG AGGCTGGGCC TGGCTATGGC CCTAGAACCT 
AACACCACCT TCCTGAGGAA GTCCCTGAAG GCCGCCTTGA AACATTTGGG CCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FANCE ( NM_021922.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_068741.1 Homo sapiens FA complementation group E (FANCE), mRNA.

Price & Availability↑

CloneID	OHu21011
Clone ID Related Accession (Same CDS sequence)	NM_021922.3 , NM_021922.2
Accession Version	NM_021922.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1611bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-14
Organism	Homo sapiens(human)
Product	Fanconi anemia group E protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL022721.1 and AF265210.1. On Aug 31, 2019 this sequence version replaced NM_021922.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF265210.1, BC046359.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGACAC CGGACGCGGG GCTCCCTGGG GCTGAGGGCG TGGAGCCGGC GCCCTGGGCG 
CAGCTGGAGG CCCCCGCCCG CCTCCTGCTG CAGGCGCTGC AGGCGGGGCC TGAGGGGGCG 
CGGCGCGGCC TGGGGGTGCT CCGGGCGCTG GGCAGCCGCG GCTGGGAGCC CTTCGACTGG 
GGTCGCTTGC TCGAGGCCCT GTGCCGGGAG GAGCCGGTCG TGCAGGGGCC TGACGGCCGT 
CTGGAGCTGA AACCACTGTT GCTGCGATTG CCCCGGATAT GCCAGAGGAA CCTGATGTCC 
CTGCTGATGG CCGTTCGGCC ATCGCTGCCG GAAAGTGGGC TCCTCTCTGT GCTGCAGATT 
GCCCAGCAGG ACCTAGCCCC TGACCCAGAT GCCTGGCTCC GTGCCCTGGG GGAATTGCTG 
CGAAGGGATT TGGGGGTGGG GACCTCCATG GAGGGAGCTT CTCCACTGTC TGAAAGATGC 
CAGAGACAGC TCCAAAGTCT ATGTAGGGGG CTGGGCCTGG GGGGCAGGAG GTTGAAATCC 
CCCCAGGCTC CAGACCCTGA AGAAGAGGAG AACAGGGACT CCCAGCAGCC TGGGAAACGC 
AGAAAGGACT CAGAGGAAGA GGCTGCCAGT CCTGAGGGGA AGAGGGTCCC CAAAAGATTA 
CGGTGTTGGG AAGAGGAAGA AGATCATGAG AAGGAGAGAC CCGAACATAA GTCACTGGAA 
TCCCTGGCAG ATGGAGGAAG TGCATCTCCT ATTAAGGACC AGCCTGTCAT GGCAGTTAAG 
ACTGGCGAGG ACGGTTCGAA TCTGGATGAT GCTAAAGGTC TGGCTGAGAG TTTGGAGTTG 
CCCAAAGCTA TCCAGGACCA GCTTCCCAGG CTGCAGCAGC TGCTGAAGAC CTTGGAGGAG 
GGGTTAGAGG GATTGGAGGA TGCCCCCCCA GTTGAGCTAC AGCTTCTTCA CGAATGTAGT 
CCCAGCCAGA TGGACTTGCT GTGTGCCCAG CTGCAGCTCC CTCAGCTCTC AGACCTCGGT 
CTCCTGCGGC TCTGCACCTG GCTGCTGGCC CTTTCACCTG ATCTCAGCCT CAGCAATGCT 
ACTGTGCTGA CCAGAAGCCT CTTTCTTGGA CGGATCCTCT CCTTGACTTC CTCAGCCTCC 
CGCCTGCTTA CAACTGCCCT GACCTCCTTC TGTGCCAAAT ATACATACCC TGTCTGCAGC 
GCCCTCCTTG ACCCTGTGCT CCAGGCCCCA GGCACAGGTC CTGCTCAAAC AGAGTTACTG 
TGTTGCCTTG TGAAGATGGA GTCCCTGGAG CCAGATGCAC AGGTTCTAAT GCTGGGACAG 
ATCTTGGAGC TGCCCTGGAA GGAGGAAACT TTCTTGGTGT TGCAGTCACT CCTAGAGCGG 
CAGGTGGAGA TGACCCCTGA GAAGTTCAGT GTCTTAATGG AGAAGCTCTG TAAAAAGGGG 
CTGGCAGCCA CCACCTCCAT GGCCTATGCC AAGCTCATGC TGACAGTGAT GACCAAGTAT 
CAGGCTAACA TCACTGAGAC CCAGAGGCTG GGCCTGGCTA TGGCCCTAGA ACCTAACACC 
ACCTTCCTGA GGAAGTCCCT GAAGGCCGCC TTGAAACATT TGGGCCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068741.1
CDS	209..1819
Translation	MATPDAGLPGAEGVEPAPWAQLEAPARLLLQALQAGPEGARRGLGVLRALGSRGWEPFDWGRLLEALCREEPVVQGPDGRLELKPLLLRLPRICQRNLMSLLMAVRPSLPESGLLSVLQIAQQDLAPDPDAWLRALGELLRRDLGVGTSMEGASPLSERCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLESLADGGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQLLKTLEEGLEGLEDAPPVELQLLHECSPSQMDLLCAQLQLPQLSDLGLLRLCTWLLALSPDLSLSNATVLTRSLFLGRILSLTSSASRLLTTALTSFCAKYTYPVCSALLDPVLQAPGTGPAQTELLCCLVKMESLEPDAQVLMLGQILELPWKEETFLVLQSLLERQVEMTPEKFSVLMEKLCKKGLAATTSMAYAKLMLTVMTKYQANITETQRLGLAMALEPNTTFLRKSLKAALKHLGP

Target ORF information:

RefSeq Version	NM_021922.3
Organism	Homo sapiens(human)
Definition	Homo sapiens FA complementation group E (FANCE), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021922.3

ORF Insert Sequence:

ATGGCGACAC CGGACGCGGG GCTCCCTGGG GCTGAGGGCG TGGAGCCGGC GCCCTGGGCG 
CAGCTGGAGG CCCCCGCCCG CCTCCTGCTG CAGGCGCTGC AGGCGGGGCC TGAGGGGGCG 
CGGCGCGGCC TGGGGGTGCT CCGGGCGCTG GGCAGCCGCG GCTGGGAGCC CTTCGACTGG 
GGTCGCTTGC TCGAGGCCCT GTGCCGGGAG GAGCCGGTCG TGCAGGGGCC TGACGGCCGT 
CTGGAGCTGA AACCACTGTT GCTGCGATTG CCCCGGATAT GCCAGAGGAA CCTGATGTCC 
CTGCTGATGG CCGTTCGGCC ATCGCTGCCG GAAAGTGGGC TCCTCTCTGT GCTGCAGATT 
GCCCAGCAGG ACCTAGCCCC TGACCCAGAT GCCTGGCTCC GTGCCCTGGG GGAATTGCTG 
CGAAGGGATT TGGGGGTGGG GACCTCCATG GAGGGAGCTT CTCCACTGTC TGAAAGATGC 
CAGAGACAGC TCCAAAGTCT ATGTAGGGGG CTGGGCCTGG GGGGCAGGAG GTTGAAATCC 
CCCCAGGCTC CAGACCCTGA AGAAGAGGAG AACAGGGACT CCCAGCAGCC TGGGAAACGC 
AGAAAGGACT CAGAGGAAGA GGCTGCCAGT CCTGAGGGGA AGAGGGTCCC CAAAAGATTA 
CGGTGTTGGG AAGAGGAAGA AGATCATGAG AAGGAGAGAC CCGAACATAA GTCACTGGAA 
TCCCTGGCAG ATGGAGGAAG TGCATCTCCT ATTAAGGACC AGCCTGTCAT GGCAGTTAAG 
ACTGGCGAGG ACGGTTCGAA TCTGGATGAT GCTAAAGGTC TGGCTGAGAG TTTGGAGTTG 
CCCAAAGCTA TCCAGGACCA GCTTCCCAGG CTGCAGCAGC TGCTGAAGAC CTTGGAGGAG 
GGGTTAGAGG GATTGGAGGA TGCCCCCCCA GTTGAGCTAC AGCTTCTTCA CGAATGTAGT 
CCCAGCCAGA TGGACTTGCT GTGTGCCCAG CTGCAGCTCC CTCAGCTCTC AGACCTCGGT 
CTCCTGCGGC TCTGCACCTG GCTGCTGGCC CTTTCACCTG ATCTCAGCCT CAGCAATGCT 
ACTGTGCTGA CCAGAAGCCT CTTTCTTGGA CGGATCCTCT CCTTGACTTC CTCAGCCTCC 
CGCCTGCTTA CAACTGCCCT GACCTCCTTC TGTGCCAAAT ATACATACCC TGTCTGCAGC 
GCCCTCCTTG ACCCTGTGCT CCAGGCCCCA GGCACAGGTC CTGCTCAAAC AGAGTTACTG 
TGTTGCCTTG TGAAGATGGA GTCCCTGGAG CCAGATGCAC AGGTTCTAAT GCTGGGACAG 
ATCTTGGAGC TGCCCTGGAA GGAGGAAACT TTCTTGGTGT TGCAGTCACT CCTAGAGCGG 
CAGGTGGAGA TGACCCCTGA GAAGTTCAGT GTCTTAATGG AGAAGCTCTG TAAAAAGGGG 
CTGGCAGCCA CCACCTCCAT GGCCTATGCC AAGCTCATGC TGACAGTGAT GACCAAGTAT 
CAGGCTAACA TCACTGAGAC CCAGAGGCTG GGCCTGGCTA TGGCCCTAGA ACCTAACACC 
ACCTTCCTGA GGAAGTCCCT GAAGGCCGCC TTGAAACATT TGGGCCCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FANCE ( XM_005248885.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005248942.1 Homo sapiens FA complementation group E (FANCE), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu40178
Clone ID Related Accession (Same CDS sequence)	XM_005248885.2
Accession Version	XM_005248885.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1590bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	Fanconi anemia group E protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_005248885.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGACAC CGGACGCGGG GCTCCCTGGG GCTGAGGGCG TGGAGCCGGC GCCCTGGGCG 
CAGCTGGAGG CCCCCGCCCG CCTCCTGCTG CAGGCGCTGC AGGCGGGGCC TGAGGGGGCG 
CGGCGCGGCC TGGGGGTGCT CCGGGCGCTG GGCAGCCGCG GCTGGGAGCC CTTCGACTGG 
GGTCGCTTGC TCGAGGCCCT GTGCCGGGAG GAGCCGGTCG TGCAGGGGCC TGACGGCCGT 
CTGGAGCTGA AACCACTGTT GCTGCGATTG CCCCGGATAT GCCAGAGGAA CCTGATGTCC 
CTGCTGATGG CCGTTCGGCC ATCGCTGCCG GAAAGTGGGC TCCTCTCTGT GCTGCAGATT 
GCCCAGCAGG ACCTAGCCCC TGACCCAGAT GCCTGGCTCC GTGCCCTGGG GGAATTGCTG 
CGAAGGGATT TGGGGGTGGG GACCTCCATG GAGGGAGCTT CTCCACTGTC TGAAAGATGC 
CAGAGACAGC TCCAAAGTCT ATGTAGGGGG CTGGGCCTGG GGGGCAGGAG GTTGAAATCC 
CCCCAGGCTC CAGACCCTGA AGAAGAGGAG AACAGGGACT CCCAGCAGCC TGGGAAACGC 
AGAAAGGACT CAGAGGAAGA GGCTGCCAGT CCTGAGGGGA AGAGGGTCCC CAAAAGATTA 
CGGTGTTGGG AAGAGGAAGA AGATCATGAG AAGGAGAGAC CCGAACATAA GTCACTGGAA 
TCCCTGGCAG ATGGAGGAAG TGCATCTCCT ATTAAGGACC AGCCTGTCAT GGCAGTTAAG 
ACTGGCGAGG ACGGTTCGAA TCTGGATGAT GCTAAAGGTC TGGCTGAGAG TTTGGAGTTG 
CCCAAAGCTA TCCAGGACCA GCTTCCCAGG CTGCAGCAGC TGCTGAAGAC CTTGGAGGAG 
GGGTTAGAGG GATTGGAGGA TGCCCCCCCA GTTGAGCTAC AGCTTCTTCA CGAATGTAGT 
CCCAGCCAGC TGCAGCTCCC TCAGCTCTCA GACCTCGGTC TCCTGCGGCT CTGCACCTGG 
CTGCTGGCCC TTTCACCTGA TCTCAGCCTC AGCAATGCTA CTGTGCTGAC CAGAAGCCTC 
TTTCTTGGAC GGATCCTCTC CTTGACTTCC TCAGCCTCCC GCCTGCTTAC AACTGCCCTG 
ACCTCCTTCT GTGCCAAATA TACATACCCT GTCTGCAGCG CCCTCCTTGA CCCTGTGCTC 
CAGGCCCCAG GCACAGGTCC TGCTCAAACA GAGTTACTGT GTTGCCTTGT GAAGATGGAG 
TCCCTGGAGC CAGATGCACA GGTTCTAATG CTGGGACAGA TCTTGGAGCT GCCCTGGAAG 
GAGGAAACTT TCTTGGTGTT GCAGTCACTC CTAGAGCGGC AGGTGGAGAT GACCCCTGAG 
AAGTTCAGTG TCTTAATGGA GAAGCTCTGT AAAAAGGGGC TGGCAGCCAC CACCTCCATG 
GCCTATGCCA AGCTCATGCT GACAGTGATG ACCAAGTATC AGGCTAACAT CACTGAGACC 
CAGAGGCTGG GCCTGGCTAT GGCCCTAGAA CCTAACACCA CCTTCCTGAG GAAGTCCCTG 
AAGGCCGCCT TGAAACATTT GGGCCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005248942.1
CDS	208..1797
Translation	MATPDAGLPGAEGVEPAPWAQLEAPARLLLQALQAGPEGARRGLGVLRALGSRGWEPFDWGRLLEALCREEPVVQGPDGRLELKPLLLRLPRICQRNLMSLLMAVRPSLPESGLLSVLQIAQQDLAPDPDAWLRALGELLRRDLGVGTSMEGASPLSERCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLESLADGGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQLLKTLEEGLEGLEDAPPVELQLLHECSPSQLQLPQLSDLGLLRLCTWLLALSPDLSLSNATVLTRSLFLGRILSLTSSASRLLTTALTSFCAKYTYPVCSALLDPVLQAPGTGPAQTELLCCLVKMESLEPDAQVLMLGQILELPWKEETFLVLQSLLERQVEMTPEKFSVLMEKLCKKGLAATTSMAYAKLMLTVMTKYQANITETQRLGLAMALEPNTTFLRKSLKAALKHLGP

Target ORF information:

RefSeq Version	XM_005248885.2
Organism	Homo sapiens(human)
Definition	Homo sapiens FA complementation group E (FANCE), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005248885.2

ORF Insert Sequence:

ATGGCGACAC CGGACGCGGG GCTCCCTGGG GCTGAGGGCG TGGAGCCGGC GCCCTGGGCG 
CAGCTGGAGG CCCCCGCCCG CCTCCTGCTG CAGGCGCTGC AGGCGGGGCC TGAGGGGGCG 
CGGCGCGGCC TGGGGGTGCT CCGGGCGCTG GGCAGCCGCG GCTGGGAGCC CTTCGACTGG 
GGTCGCTTGC TCGAGGCCCT GTGCCGGGAG GAGCCGGTCG TGCAGGGGCC TGACGGCCGT 
CTGGAGCTGA AACCACTGTT GCTGCGATTG CCCCGGATAT GCCAGAGGAA CCTGATGTCC 
CTGCTGATGG CCGTTCGGCC ATCGCTGCCG GAAAGTGGGC TCCTCTCTGT GCTGCAGATT 
GCCCAGCAGG ACCTAGCCCC TGACCCAGAT GCCTGGCTCC GTGCCCTGGG GGAATTGCTG 
CGAAGGGATT TGGGGGTGGG GACCTCCATG GAGGGAGCTT CTCCACTGTC TGAAAGATGC 
CAGAGACAGC TCCAAAGTCT ATGTAGGGGG CTGGGCCTGG GGGGCAGGAG GTTGAAATCC 
CCCCAGGCTC CAGACCCTGA AGAAGAGGAG AACAGGGACT CCCAGCAGCC TGGGAAACGC 
AGAAAGGACT CAGAGGAAGA GGCTGCCAGT CCTGAGGGGA AGAGGGTCCC CAAAAGATTA 
CGGTGTTGGG AAGAGGAAGA AGATCATGAG AAGGAGAGAC CCGAACATAA GTCACTGGAA 
TCCCTGGCAG ATGGAGGAAG TGCATCTCCT ATTAAGGACC AGCCTGTCAT GGCAGTTAAG 
ACTGGCGAGG ACGGTTCGAA TCTGGATGAT GCTAAAGGTC TGGCTGAGAG TTTGGAGTTG 
CCCAAAGCTA TCCAGGACCA GCTTCCCAGG CTGCAGCAGC TGCTGAAGAC CTTGGAGGAG 
GGGTTAGAGG GATTGGAGGA TGCCCCCCCA GTTGAGCTAC AGCTTCTTCA CGAATGTAGT 
CCCAGCCAGC TGCAGCTCCC TCAGCTCTCA GACCTCGGTC TCCTGCGGCT CTGCACCTGG 
CTGCTGGCCC TTTCACCTGA TCTCAGCCTC AGCAATGCTA CTGTGCTGAC CAGAAGCCTC 
TTTCTTGGAC GGATCCTCTC CTTGACTTCC TCAGCCTCCC GCCTGCTTAC AACTGCCCTG 
ACCTCCTTCT GTGCCAAATA TACATACCCT GTCTGCAGCG CCCTCCTTGA CCCTGTGCTC 
CAGGCCCCAG GCACAGGTCC TGCTCAAACA GAGTTACTGT GTTGCCTTGT GAAGATGGAG 
TCCCTGGAGC CAGATGCACA GGTTCTAATG CTGGGACAGA TCTTGGAGCT GCCCTGGAAG 
GAGGAAACTT TCTTGGTGTT GCAGTCACTC CTAGAGCGGC AGGTGGAGAT GACCCCTGAG 
AAGTTCAGTG TCTTAATGGA GAAGCTCTGT AAAAAGGGGC TGGCAGCCAC CACCTCCATG 
GCCTATGCCA AGCTCATGCT GACAGTGATG ACCAAGTATC AGGCTAACAT CACTGAGACC 
CAGAGGCTGG GCCTGGCTAT GGCCCTAGAA CCTAACACCA CCTTCCTGAG GAAGTCCCTG 
AAGGCCGCCT TGAAACATTT GGGCCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FANCE ( XM_005248886.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005248943.1 Homo sapiens FA complementation group E (FANCE), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu40179
Clone ID Related Accession (Same CDS sequence)	XM_005248886.2
Accession Version	XM_005248886.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1542bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	Fanconi anemia group E protein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_005248886.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGACAC CGGACGCGGG GCTCCCTGGG GCTGAGGGCG TGGAGCCGGC GCCCTGGGCG 
CAGCTGGAGG CCCCCGCCCG CCTCCTGCTG CAGGCGCTGC AGGCGGGGCC TGAGGGGGCG 
CGGCGCGGCC TGGGGGTGCT CCGGGCGCTG GGCAGCCGCG GCTGGGAGCC CTTCGACTGG 
GGTCGCTTGC TCGAGGCCCT GTGCCGGGAG GAGCCGGTCG TGCAGGGGCC TGACGGCCGT 
CTGGAGCTGA AACCACTGTT GCTGCGATTG CCCCGGATAT GCCAGAGGAA CCTGATGTCC 
CTGCTGATGG CCGTTCGGCC ATCGCTGCCG GAAAGTGGGC TCCTCTCTGT GCTGCAGATT 
GCCCAGCAGG ACCTAGCCCC TGACCCAGAT GCCTGGCTCC GTGCCCTGGG GGAATTGCTG 
CGAAGGGATT TGGGGGTGGG GACCTCCATG GAGGGAGCTT CTCCACTGTC TGAAAGATGC 
CAGAGACAGC TCCAAAGTCT ATGTAGGGGG CTGGGCCTGG GGGGCAGGAG GTTGAAATCC 
CCCCAGGCTC CAGACCCTGA AGAAGAGGAG AACAGGGACT CCCAGCAGCC TGGGAAACGC 
AGAAAGGACT CAGAGGAAGA GGCTGCCAGT CCTGAGGGGA AGAGGGTCCC CAAAAGATTA 
CGGTGTTGGG AAGAGGAAGA AGATCATGAG AAGGAGAGAC CCGAACATAA GTCACTGGAA 
TCCCTGGCAG ATGGAGGAAG TGCATCTCCT ATTAAGGACC AGCCTGTCAT GGCAGTTAAG 
ACTGGCGAGG ACGGTTCGAA TCTGGATGAT GCTAAAGGTC TGGCTGAGAG TTTGGAGTTG 
CCCAAAGCTA TCCAGGACCA GCTTCCCAGG CTGCAGCAGC TGCTGAAGAC CTTGGAGGAG 
ATGGACTTGC TGTGTGCCCA GCTGCAGCTC CCTCAGCTCT CAGACCTCGG TCTCCTGCGG 
CTCTGCACCT GGCTGCTGGC CCTTTCACCT GATCTCAGCC TCAGCAATGC TACTGTGCTG 
ACCAGAAGCC TCTTTCTTGG ACGGATCCTC TCCTTGACTT CCTCAGCCTC CCGCCTGCTT 
ACAACTGCCC TGACCTCCTT CTGTGCCAAA TATACATACC CTGTCTGCAG CGCCCTCCTT 
GACCCTGTGC TCCAGGCCCC AGGCACAGGT CCTGCTCAAA CAGAGTTACT GTGTTGCCTT 
GTGAAGATGG AGTCCCTGGA GCCAGATGCA CAGGTTCTAA TGCTGGGACA GATCTTGGAG 
CTGCCCTGGA AGGAGGAAAC TTTCTTGGTG TTGCAGTCAC TCCTAGAGCG GCAGGTGGAG 
ATGACCCCTG AGAAGTTCAG TGTCTTAATG GAGAAGCTCT GTAAAAAGGG GCTGGCAGCC 
ACCACCTCCA TGGCCTATGC CAAGCTCATG CTGACAGTGA TGACCAAGTA TCAGGCTAAC 
ATCACTGAGA CCCAGAGGCT GGGCCTGGCT ATGGCCCTAG AACCTAACAC CACCTTCCTG 
AGGAAGTCCC TGAAGGCCGC CTTGAAACAT TTGGGCCCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005248943.1
CDS	208..1749
Translation	MATPDAGLPGAEGVEPAPWAQLEAPARLLLQALQAGPEGARRGLGVLRALGSRGWEPFDWGRLLEALCREEPVVQGPDGRLELKPLLLRLPRICQRNLMSLLMAVRPSLPESGLLSVLQIAQQDLAPDPDAWLRALGELLRRDLGVGTSMEGASPLSERCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLESLADGGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQLLKTLEEMDLLCAQLQLPQLSDLGLLRLCTWLLALSPDLSLSNATVLTRSLFLGRILSLTSSASRLLTTALTSFCAKYTYPVCSALLDPVLQAPGTGPAQTELLCCLVKMESLEPDAQVLMLGQILELPWKEETFLVLQSLLERQVEMTPEKFSVLMEKLCKKGLAATTSMAYAKLMLTVMTKYQANITETQRLGLAMALEPNTTFLRKSLKAALKHLGP

Target ORF information:

RefSeq Version	XM_005248886.2
Organism	Homo sapiens(human)
Definition	Homo sapiens FA complementation group E (FANCE), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005248886.2

ORF Insert Sequence:

ATGGCGACAC CGGACGCGGG GCTCCCTGGG GCTGAGGGCG TGGAGCCGGC GCCCTGGGCG 
CAGCTGGAGG CCCCCGCCCG CCTCCTGCTG CAGGCGCTGC AGGCGGGGCC TGAGGGGGCG 
CGGCGCGGCC TGGGGGTGCT CCGGGCGCTG GGCAGCCGCG GCTGGGAGCC CTTCGACTGG 
GGTCGCTTGC TCGAGGCCCT GTGCCGGGAG GAGCCGGTCG TGCAGGGGCC TGACGGCCGT 
CTGGAGCTGA AACCACTGTT GCTGCGATTG CCCCGGATAT GCCAGAGGAA CCTGATGTCC 
CTGCTGATGG CCGTTCGGCC ATCGCTGCCG GAAAGTGGGC TCCTCTCTGT GCTGCAGATT 
GCCCAGCAGG ACCTAGCCCC TGACCCAGAT GCCTGGCTCC GTGCCCTGGG GGAATTGCTG 
CGAAGGGATT TGGGGGTGGG GACCTCCATG GAGGGAGCTT CTCCACTGTC TGAAAGATGC 
CAGAGACAGC TCCAAAGTCT ATGTAGGGGG CTGGGCCTGG GGGGCAGGAG GTTGAAATCC 
CCCCAGGCTC CAGACCCTGA AGAAGAGGAG AACAGGGACT CCCAGCAGCC TGGGAAACGC 
AGAAAGGACT CAGAGGAAGA GGCTGCCAGT CCTGAGGGGA AGAGGGTCCC CAAAAGATTA 
CGGTGTTGGG AAGAGGAAGA AGATCATGAG AAGGAGAGAC CCGAACATAA GTCACTGGAA 
TCCCTGGCAG ATGGAGGAAG TGCATCTCCT ATTAAGGACC AGCCTGTCAT GGCAGTTAAG 
ACTGGCGAGG ACGGTTCGAA TCTGGATGAT GCTAAAGGTC TGGCTGAGAG TTTGGAGTTG 
CCCAAAGCTA TCCAGGACCA GCTTCCCAGG CTGCAGCAGC TGCTGAAGAC CTTGGAGGAG 
ATGGACTTGC TGTGTGCCCA GCTGCAGCTC CCTCAGCTCT CAGACCTCGG TCTCCTGCGG 
CTCTGCACCT GGCTGCTGGC CCTTTCACCT GATCTCAGCC TCAGCAATGC TACTGTGCTG 
ACCAGAAGCC TCTTTCTTGG ACGGATCCTC TCCTTGACTT CCTCAGCCTC CCGCCTGCTT 
ACAACTGCCC TGACCTCCTT CTGTGCCAAA TATACATACC CTGTCTGCAG CGCCCTCCTT 
GACCCTGTGC TCCAGGCCCC AGGCACAGGT CCTGCTCAAA CAGAGTTACT GTGTTGCCTT 
GTGAAGATGG AGTCCCTGGA GCCAGATGCA CAGGTTCTAA TGCTGGGACA GATCTTGGAG 
CTGCCCTGGA AGGAGGAAAC TTTCTTGGTG TTGCAGTCAC TCCTAGAGCG GCAGGTGGAG 
ATGACCCCTG AGAAGTTCAG TGTCTTAATG GAGAAGCTCT GTAAAAAGGG GCTGGCAGCC 
ACCACCTCCA TGGCCTATGC CAAGCTCATG CTGACAGTGA TGACCAAGTA TCAGGCTAAC 
ATCACTGAGA CCCAGAGGCT GGGCCTGGCT ATGGCCCTAG AACCTAACAC CACCTTCCTG 
AGGAAGTCCC TGAAGGCCGC CTTGAAACAT TTGGGCCCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FANCE ( XM_005248887.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005248944.1 Homo sapiens FA complementation group E (FANCE), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu40180
Clone ID Related Accession (Same CDS sequence)	XM_005248887.2
Accession Version	XM_005248887.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1485bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	Fanconi anemia group E protein isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_005248887.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGACAC CGGACGCGGG GCTCCCTGGG GCTGAGGGCG TGGAGCCGGC GCCCTGGGCG 
CAGCTGGAGG CCCCCGCCCG CCTCCTGCTG CAGGCGCTGC AGGCGGGGCC TGAGGGGGCG 
CGGCGCGGCC TGGGGGTGCT CCGGGCGCTG GGCAGCCGCG GCTGGGAGCC CTTCGACTGG 
GGTCGCTTGC TCGAGGCCCT GTGCCGGGAG GAGCCGGTCG TGCAGGGGCC TGACGGCCGT 
CTGGAGCTGA AACCACTGTT GCTGCGATTG CCCCGGATAT GCCAGAGGAA CCTGATGTCC 
CTGCTGATGG CCGTTCGGCC ATCGCTGCCG GAAAGTGGGC TCCTCTCTGT GCTGCAGATT 
GCCCAGCAGG ACCTAGCCCC TGACCCAGAT GCCTGGCTCC GTGCCCTGGG GGAATTGCTG 
CGAAGGGATT TGGGGGTGGG GACCTCCATG GAGGGAGCTT CTCCACTGTC TGAAAGATGC 
CAGAGACAGC TCCAAAGTCT ATGTAGGGGG CTGGGCCTGG GGGGCAGGAG GTTGAAATCC 
CCCCAGGCTC CAGACCCTGA AGAAGAGGAG AACAGGGACT CCCAGCAGCC TGGGAAACGC 
AGAAAGGACT CAGAGGAAGA GGCTGCCAGT CCTGAGGGGA AGAGGGTCCC CAAAAGATTA 
CGGTGTTGGG AAGAGGAAGA AGATCATGAG AAGGAGAGAC CCGAACATAA GTCACTGGAA 
TCCCTGGCAG ATGGAGGAAG TGCATCTCCT ATTAAGGACC AGCCTGTCAT GGCAGTTAAG 
ACTGGCGAGG ACGGTTCGAA TCTGGATGAT GCTAAAGGTC TGGCTGAGAG TTTGGAGTTG 
CCCAAAGCTA TCCAGGACCA GCTTCCCAGG CTGCAGCAGC TGCTGAAGAC CTTGGAGGAG 
GGGTTAGAGG GATTGGAGGA TGCCCCCCCA GTTGAGCTAC AGCTTCTTCA CGAATGTAGT 
CCCAGCCAGA TGGACTTGCT GTGTGCCCAG CTGCAGCTCC CTCAGCTCTC AGACCTCGGT 
CTCCTGCGGC TCTGCACCTG GCTGCTGGCC CTTTCACCTG ATCTCAGCCT CAGCAATGCT 
ACTGTGCTGA CCAGAAGCCT CTTTCTTGGA CGGATCCTCT CCTTGACTTC CTCAGCCTCC 
CGCCTGCTTA CAACTGCCCT GACCTCCTTC TGTGCCAAAT ATACATACCC TGTCTGCAGC 
GCCCTCCTTG ACCCTGTGCT CCAGGCCCCA GGCACAGGTC CTGCTCAAAC AGAGTTACTG 
TGTTGCCTTG TGAAGATGGA GTCCCTGGAG CCAGATGCAC AGGTTCTAAT GCTGGGACAG 
ATCTTGGAGC TGCCCTGGAA GGAGGAAACT TTCTTGGTGT TGCAGTCACT CCTAGAGCGG 
CAGATCACTG AGACCCAGAG GCTGGGCCTG GCTATGGCCC TAGAACCTAA CACCACCTTC 
CTGAGGAAGT CCCTGAAGGC CGCCTTGAAA CATTTGGGCC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005248944.1
CDS	208..1692
Translation	MATPDAGLPGAEGVEPAPWAQLEAPARLLLQALQAGPEGARRGLGVLRALGSRGWEPFDWGRLLEALCREEPVVQGPDGRLELKPLLLRLPRICQRNLMSLLMAVRPSLPESGLLSVLQIAQQDLAPDPDAWLRALGELLRRDLGVGTSMEGASPLSERCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLESLADGGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQLLKTLEEGLEGLEDAPPVELQLLHECSPSQMDLLCAQLQLPQLSDLGLLRLCTWLLALSPDLSLSNATVLTRSLFLGRILSLTSSASRLLTTALTSFCAKYTYPVCSALLDPVLQAPGTGPAQTELLCCLVKMESLEPDAQVLMLGQILELPWKEETFLVLQSLLERQITETQRLGLAMALEPNTTFLRKSLKAALKHLGP

Target ORF information:

RefSeq Version	XM_005248887.2
Organism	Homo sapiens(human)
Definition	Homo sapiens FA complementation group E (FANCE), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005248887.2

ORF Insert Sequence:

ATGGCGACAC CGGACGCGGG GCTCCCTGGG GCTGAGGGCG TGGAGCCGGC GCCCTGGGCG 
CAGCTGGAGG CCCCCGCCCG CCTCCTGCTG CAGGCGCTGC AGGCGGGGCC TGAGGGGGCG 
CGGCGCGGCC TGGGGGTGCT CCGGGCGCTG GGCAGCCGCG GCTGGGAGCC CTTCGACTGG 
GGTCGCTTGC TCGAGGCCCT GTGCCGGGAG GAGCCGGTCG TGCAGGGGCC TGACGGCCGT 
CTGGAGCTGA AACCACTGTT GCTGCGATTG CCCCGGATAT GCCAGAGGAA CCTGATGTCC 
CTGCTGATGG CCGTTCGGCC ATCGCTGCCG GAAAGTGGGC TCCTCTCTGT GCTGCAGATT 
GCCCAGCAGG ACCTAGCCCC TGACCCAGAT GCCTGGCTCC GTGCCCTGGG GGAATTGCTG 
CGAAGGGATT TGGGGGTGGG GACCTCCATG GAGGGAGCTT CTCCACTGTC TGAAAGATGC 
CAGAGACAGC TCCAAAGTCT ATGTAGGGGG CTGGGCCTGG GGGGCAGGAG GTTGAAATCC 
CCCCAGGCTC CAGACCCTGA AGAAGAGGAG AACAGGGACT CCCAGCAGCC TGGGAAACGC 
AGAAAGGACT CAGAGGAAGA GGCTGCCAGT CCTGAGGGGA AGAGGGTCCC CAAAAGATTA 
CGGTGTTGGG AAGAGGAAGA AGATCATGAG AAGGAGAGAC CCGAACATAA GTCACTGGAA 
TCCCTGGCAG ATGGAGGAAG TGCATCTCCT ATTAAGGACC AGCCTGTCAT GGCAGTTAAG 
ACTGGCGAGG ACGGTTCGAA TCTGGATGAT GCTAAAGGTC TGGCTGAGAG TTTGGAGTTG 
CCCAAAGCTA TCCAGGACCA GCTTCCCAGG CTGCAGCAGC TGCTGAAGAC CTTGGAGGAG 
GGGTTAGAGG GATTGGAGGA TGCCCCCCCA GTTGAGCTAC AGCTTCTTCA CGAATGTAGT 
CCCAGCCAGA TGGACTTGCT GTGTGCCCAG CTGCAGCTCC CTCAGCTCTC AGACCTCGGT 
CTCCTGCGGC TCTGCACCTG GCTGCTGGCC CTTTCACCTG ATCTCAGCCT CAGCAATGCT 
ACTGTGCTGA CCAGAAGCCT CTTTCTTGGA CGGATCCTCT CCTTGACTTC CTCAGCCTCC 
CGCCTGCTTA CAACTGCCCT GACCTCCTTC TGTGCCAAAT ATACATACCC TGTCTGCAGC 
GCCCTCCTTG ACCCTGTGCT CCAGGCCCCA GGCACAGGTC CTGCTCAAAC AGAGTTACTG 
TGTTGCCTTG TGAAGATGGA GTCCCTGGAG CCAGATGCAC AGGTTCTAAT GCTGGGACAG 
ATCTTGGAGC TGCCCTGGAA GGAGGAAACT TTCTTGGTGT TGCAGTCACT CCTAGAGCGG 
CAGATCACTG AGACCCAGAG GCTGGGCCTG GCTATGGCCC TAGAACCTAA CACCACCTTC 
CTGAGGAAGT CCCTGAAGGC CGCCTTGAAA CATTTGGGCC CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FANCE ( XM_005248888.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005248945.1 Homo sapiens FA complementation group E (FANCE), transcript variant X4, mRNA.

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CloneID	OHu40181
Clone ID Related Accession (Same CDS sequence)	XM_005248888.3
Accession Version	XM_005248888.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1356bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	Fanconi anemia group E protein isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005248888.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGACAC CGGACGCGGG GCTCCCTGGG GCTGAGGGCG TGGAGCCGGC GCCCTGGGCG 
CAGCTGGAGG CCCCCGCCCG CCTCCTGCTG CAGGCGCTGC AGGCGGGGCC TGAGGGGGCG 
CGGCGCGGCC TGGGGGTGCT CCGGGCGCTG GGCAGCCGCG GCTGGGAGCC CTTCGACTGG 
GGTCGCTTGC TCGAGGCCCT GTGCCGGGAG GAGCCGGTCG TGCAGGGGCC TGACGGCCGT 
CTGGAGCTGA AACCACTGTT GCTGCGATTG CCCCGGATAT GCCAGAGGAA CCTGATGTCC 
CTGCTGATGG CCGTTCGGCC ATCGCTGCCG GAAAGTGGGC TCCTCTCTGT GCTGCAGATT 
GCCCAGCAGG ACCTAGCCCC TGACCCAGAT GCCTGGCTCC GTGCCCTGGG GGAATTGCTG 
CGAAGGGATT TGGGGGTGGG GACCTCCATG GAGGGAGCTT CTCCACTGTC TGAAAGATGC 
CAGAGACAGC TCCAAAGTCT ATGTAGGGGG CTGGGCCTGG GGGGCAGGAG GTTGAAATCC 
CCCCAGGCTC CAGACCCTGA AGAAGAGGAG AACAGGGACT CCCAGCAGCC TGGGAAACGC 
AGAAAGGACT CAGAGGAAGA GGCTGCCAGT CCTGAGGGGA AGAGGGTCCC CAAAAGATTA 
CGGTGTTGGG AAGAGGAAGA AGATCATGAG AAGGAGAGAC CCGAACATAA GTCACTGGAA 
TCCCTGGCAG ATGGAGGAAG TGCATCTCCT ATTAAGGACC AGCCTGTCAT GGCAGTTAAG 
ACTGGCGAGG ACGGTTCGAA TCTGGATGAT GCTAAAGGTC TGGCTGAGAG TTTGGAGTTG 
CCCAAAGCTA TCCAGGACCA GCTTCCCAGG CTGCAGCAGC TGCTGAAGAC CTTGGAGGAG 
GGGTTAGAGG GATTGGAGGA TGCCCCCCCA GTTGAGCTAC AGCTTCTTCA CGAATGTAGT 
CCCAGCCAGA TGGACTTGCT GTGTGCCCAG CTGCAGCTCC CTCAGCTCTC AGACCTCGGT 
CTCCTGCGGC TCTGCACCTG GCTGCTGGCC CTTTCACCTG ATCTCAGCCT CAGCAATGCT 
ACTGTGCTGA CCAGAAGCCT CTTTCTTGGA CGGATCCTCT CCTTGACTTC CTCAGCCTCC 
CGCCTGCTTA CAACTGCCCT GACCTCCTTC TGTGCCAAAT ATACATACCC TGTCTGCAGC 
GCCCTCCTTG ACCCTGTGCT CCAGGCCCCA GGCACAGGTC CTGCTCAAAC AGAGTTACTG 
TGTTGCCTTG TGAAGATGGA GTCCCTGGAG CCAGATGCAC AGGTTCTAAT GCTGGGATCA 
CTGAGACCCA GAGGCTGGGC CTGGCTATGG CCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005248945.1
CDS	208..1563
Translation	MATPDAGLPGAEGVEPAPWAQLEAPARLLLQALQAGPEGARRGLGVLRALGSRGWEPFDWGRLLEALCREEPVVQGPDGRLELKPLLLRLPRICQRNLMSLLMAVRPSLPESGLLSVLQIAQQDLAPDPDAWLRALGELLRRDLGVGTSMEGASPLSERCQRQLQSLCRGLGLGGRRLKSPQAPDPEEEENRDSQQPGKRRKDSEEEAASPEGKRVPKRLRCWEEEEDHEKERPEHKSLESLADGGSASPIKDQPVMAVKTGEDGSNLDDAKGLAESLELPKAIQDQLPRLQQLLKTLEEGLEGLEDAPPVELQLLHECSPSQMDLLCAQLQLPQLSDLGLLRLCTWLLALSPDLSLSNATVLTRSLFLGRILSLTSSASRLLTTALTSFCAKYTYPVCSALLDPVLQAPGTGPAQTELLCCLVKMESLEPDAQVLMLGSLRPRGWAWLWP

Target ORF information:

RefSeq Version	XM_005248888.3
Organism	Homo sapiens(human)
Definition	Homo sapiens FA complementation group E (FANCE), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005248888.3

ORF Insert Sequence:

ATGGCGACAC CGGACGCGGG GCTCCCTGGG GCTGAGGGCG TGGAGCCGGC GCCCTGGGCG 
CAGCTGGAGG CCCCCGCCCG CCTCCTGCTG CAGGCGCTGC AGGCGGGGCC TGAGGGGGCG 
CGGCGCGGCC TGGGGGTGCT CCGGGCGCTG GGCAGCCGCG GCTGGGAGCC CTTCGACTGG 
GGTCGCTTGC TCGAGGCCCT GTGCCGGGAG GAGCCGGTCG TGCAGGGGCC TGACGGCCGT 
CTGGAGCTGA AACCACTGTT GCTGCGATTG CCCCGGATAT GCCAGAGGAA CCTGATGTCC 
CTGCTGATGG CCGTTCGGCC ATCGCTGCCG GAAAGTGGGC TCCTCTCTGT GCTGCAGATT 
GCCCAGCAGG ACCTAGCCCC TGACCCAGAT GCCTGGCTCC GTGCCCTGGG GGAATTGCTG 
CGAAGGGATT TGGGGGTGGG GACCTCCATG GAGGGAGCTT CTCCACTGTC TGAAAGATGC 
CAGAGACAGC TCCAAAGTCT ATGTAGGGGG CTGGGCCTGG GGGGCAGGAG GTTGAAATCC 
CCCCAGGCTC CAGACCCTGA AGAAGAGGAG AACAGGGACT CCCAGCAGCC TGGGAAACGC 
AGAAAGGACT CAGAGGAAGA GGCTGCCAGT CCTGAGGGGA AGAGGGTCCC CAAAAGATTA 
CGGTGTTGGG AAGAGGAAGA AGATCATGAG AAGGAGAGAC CCGAACATAA GTCACTGGAA 
TCCCTGGCAG ATGGAGGAAG TGCATCTCCT ATTAAGGACC AGCCTGTCAT GGCAGTTAAG 
ACTGGCGAGG ACGGTTCGAA TCTGGATGAT GCTAAAGGTC TGGCTGAGAG TTTGGAGTTG 
CCCAAAGCTA TCCAGGACCA GCTTCCCAGG CTGCAGCAGC TGCTGAAGAC CTTGGAGGAG 
GGGTTAGAGG GATTGGAGGA TGCCCCCCCA GTTGAGCTAC AGCTTCTTCA CGAATGTAGT 
CCCAGCCAGA TGGACTTGCT GTGTGCCCAG CTGCAGCTCC CTCAGCTCTC AGACCTCGGT 
CTCCTGCGGC TCTGCACCTG GCTGCTGGCC CTTTCACCTG ATCTCAGCCT CAGCAATGCT 
ACTGTGCTGA CCAGAAGCCT CTTTCTTGGA CGGATCCTCT CCTTGACTTC CTCAGCCTCC 
CGCCTGCTTA CAACTGCCCT GACCTCCTTC TGTGCCAAAT ATACATACCC TGTCTGCAGC 
GCCCTCCTTG ACCCTGTGCT CCAGGCCCCA GGCACAGGTC CTGCTCAAAC AGAGTTACTG 
TGTTGCCTTG TGAAGATGGA GTCCCTGGAG CCAGATGCAC AGGTTCTAAT GCTGGGATCA 
CTGAGACCCA GAGGCTGGGC CTGGCTATGG CCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Analysis of a FANCE Splice Isoform in Regard to DNA Repair.
Journal of molecular biology427(19)3056-73(2015 Sep)
Bouffard F,Plourde K,B?langer S,Ouellette G,Labrie Y,Durocher F

The carboxyl terminus of FANCE recruits FANCD2 to the Fanconi Anemia (FA) E3 ligase complex to promote the FA DNA repair pathway.
The Journal of biological chemistry289(10)7003-10(2014 Mar)
Polito D,Cukras S,Wang X,Spence P,Moreau L,D'Andrea AD,Kee Y

Regulation of Rev1 by the Fanconi anemia core complex.
Nature structural & molecular biology19(2)164-70(2012 Jan)
Kim H,Yang K,Dejsuphong D,D'Andrea AD

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
PLoS genetics8(12)e1003098(2012)
Hancock DB,Soler Artigas M,Gharib SA,Henry A,Manichaikul A,Ramasamy A,Loth DW,Imboden M,Koch B,McArdle WL,Smith AV,Smolonska J,Sood A,Tang W,Wilk JB,Zhai G,Zhao JH,Aschard H,Burkart KM,Curjuric I,Eijgelsheim M,Elliott P,Gu X,Harris TB,Janson C,Homuth G,Hysi PG,Liu JZ,Loehr LR,Lohman K,Loos RJ,Manning AK,Marciante KD,Obeidat M,Postma DS,Aldrich MC,Brusselle GG,Chen TH,Eiriksdottir G,Franceschini N,Heinrich J,Rotter JI,Wijmenga C,Williams OD,Bentley AR,Hofman A,Laurie CC,Lumley T,Morrison AC,Joubert BR,Rivadeneira F,Couper DJ,Kritchevsky SB,Liu Y,Wjst M,Wain LV,Vonk JM,Uitterlinden AG,Rochat T,Rich SS,Psaty BM,O'Connor GT,North KE,Mirel DB,Meibohm B,Launer LJ,Khaw KT,Hartikainen AL,Hammond CJ,Gl?ser S,Marchini J,Kraft P,Wareham NJ,V?lzke H,Stricker BH,Spector TD,Probst-Hensch NM,Jarvis D,Jarvelin MR,Heckbert SR,Gudnason V,Boezen HM,Barr RG,Cassano PA,Strachan DP,Fornage M,Hall IP,Dupuis J,Tobin MD,London SJ

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FANCE cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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