ALDH2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ALDH2
Entrez Gene ID	217
Full Name	aldehyde dehydrogenase 2 family (mitochondrial)
Synonyms	ALDH-E2,ALDHI,ALDM
General protein information	Preferred Names aldehyde dehydrogenase 2 family (mitochondrial) Names aldehyde dehydrogenase, mitochondrial ALDH class 2 acetaldehyde dehydrogenase 2 liver mitochondrial ALDH nucleus-encoded mitochondrial aldehyde dehydrogenase 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q24.12
Summary	This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2016].
Disorder MIM:	100650
Disorder Html:	Alcohol sensitivity, acute, 610251 (3); {Hangover, susceptibility to}, 610251 (3); {Sublingual nitroglycerin, susceptibility to poor response to} (3); {Esophageal cancer, alcohol-related, susceptibility to} (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_000690.3	NP_000681.2	aldehyde dehydrogenase, mitochondrial isoform 1 precursor
NM_001204889.1	NP_001191818.1	aldehyde dehydrogenase, mitochondrial isoform 2 precursor
NM_000690.4	NP_000681.2	aldehyde dehydrogenase, mitochondrial isoform 1 precursor
NM_001204889.2	NP_001191818.1	aldehyde dehydrogenase, mitochondrial isoform 2 precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ALDH2	NP_001068835.1
Gallus gallus (chicken)	ALDH2	XP_415171.3
Kluyveromyces lactis	KLLA0C07777g	XP_452546.1
Neurospora crassa	NCU03415	XP_956862.1
Pan troglodytes (chimpanzee)	ALDH2	XP_509379.3
Danio rerio (zebrafish)	aldh2l	XP_002662252.1
Danio rerio (zebrafish)	aldh2.2	NP_998466.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003652	XP_313425.3
Caenorhabditis elegans (roundworm)	alh-1	NP_498081.2
Arabidopsis thaliana (thale cress)	ALDH2B4	NP_190383.1
Xenopus tropicalis (tropical clawed frog)	aldh2	NP_001004907.1
Canis lupus familiaris (dog)	ALDH2	XP_853628.1
Eremothecium gossypii	AGOS_ACL044W	NP_983360.1
	ALDH2	XP_002808038.1
Mus musculus (house mouse)	Aldh2	NP_033786.1
Drosophila melanogaster (fruit fly)	Aldh	NP_609285.1
Magnaporthe oryzae (rice blast fungus)	MGG_03900	XP_003719976.1
Homo sapiens (human)	ALDH2	NP_000681.2
Rattus norvegicus (Norway rat)	Aldh2	NP_115792.1
Danio rerio (zebrafish)	aldh2.1	NP_956784.1
Caenorhabditis elegans (roundworm)	alh-2	NP_503467.2
Saccharomyces cerevisiae (baker's yeast)	ALD5	NP_010996.2
Schizosaccharomyces pombe (fission yeast)	SPAC9E9.09c	NP_594582.1

Gene Ontology

The following ALDH2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ALDH2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23457	NM_000690.4 Latest version!	Homo sapiens aldehyde dehydrogenase 2 family member (ALDH2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu23602	NM_001204889.2 Latest version!	Homo sapiens aldehyde dehydrogenase 2 family member (ALDH2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu23457	NM_000690.3	Homo sapiens aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu23602	NM_001204889.1	Homo sapiens aldehyde dehydrogenase 2 family member (ALDH2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ALDH2 ( NM_000690.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000681.2 Homo sapiens aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23457
Clone ID Related Accession (Same CDS sequence)	NM_000690.3 , NM_000690.4
Accession Version	NM_000690.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-31
Organism	Homo sapiens(human)
Product	aldehyde dehydrogenase, mitochondrial isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC353712.1, BC002967.1 and CB851683.1. This sequence is a reference standard in the RefSeqGene project. On Mar 11, 2011 this sequence version replaced NM_000690.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.276687.1, SRR1163655.616854.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTTGCGCG CTGCCGCCCG CTTCGGGCCC CGCCTGGGCC GCCGCCTCTT GTCAGCCGCC 
GCCACCCAGG CCGTGCCTGC CCCCAACCAG CAGCCCGAGG TCTTCTGCAA CCAGATTTTC 
ATAAACAATG AATGGCACGA TGCCGTCAGC AGGAAAACAT TCCCCACCGT CAATCCGTCC 
ACTGGAGAGG TCATCTGTCA GGTAGCTGAA GGGGACAAGG AAGATGTGGA CAAGGCAGTG 
AAGGCCGCCC GGGCCGCCTT CCAGCTGGGC TCACCTTGGC GCCGCATGGA CGCATCACAC 
AGGGGCCGGC TGCTGAACCG CCTGGCCGAT CTGATCGAGC GGGACCGGAC CTACCTGGCG 
GCCTTGGAGA CCCTGGACAA TGGCAAGCCC TATGTCATCT CCTACCTGGT GGATTTGGAC 
ATGGTCCTCA AATGTCTCCG GTATTATGCC GGCTGGGCTG ATAAGTACCA CGGGAAAACC 
ATCCCCATTG ACGGAGACTT CTTCAGCTAC ACACGCCATG AACCTGTGGG GGTGTGCGGG 
CAGATCATTC CGTGGAATTT CCCGCTCCTG ATGCAAGCAT GGAAGCTGGG CCCAGCCTTG 
GCAACTGGAA ACGTGGTTGT GATGAAGGTA GCTGAGCAGA CACCCCTCAC CGCCCTCTAT 
GTGGCCAACC TGATCAAGGA GGCTGGCTTT CCCCCTGGTG TGGTCAACAT TGTGCCTGGA 
TTTGGCCCCA CGGCTGGGGC CGCCATTGCC TCCCATGAGG ATGTGGACAA AGTGGCATTC 
ACAGGCTCCA CTGAGATTGG CCGCGTAATC CAGGTTGCTG CTGGGAGCAG CAACCTCAAG 
AGAGTGACCT TGGAGCTGGG GGGGAAGAGC CCCAACATCA TCATGTCAGA TGCCGATATG 
GATTGGGCCG TGGAACAGGC CCACTTCGCC CTGTTCTTCA ACCAGGGCCA GTGCTGCTGT 
GCCGGCTCCC GGACCTTCGT GCAGGAGGAC ATCTATGATG AGTTTGTGGA GCGGAGCGTT 
GCCCGGGCCA AGTCTCGGGT GGTCGGGAAC CCCTTTGATA GCAAGACCGA GCAGGGGCCG 
CAGGTGGATG AAACTCAGTT TAAGAAGATC CTCGGCTACA TCAACACGGG GAAGCAAGAG 
GGGGCGAAGC TGCTGTGTGG TGGGGGCATT GCTGCTGACC GTGGTTACTT CATCCAGCCC 
ACTGTGTTTG GAGATGTGCA GGATGGCATG ACCATCGCCA AGGAGGAGAT CTTCGGGCCA 
GTGATGCAGA TCCTGAAGTT CAAGACCATA GAGGAGGTTG TTGGGAGAGC CAACAATTCC 
ACGTACGGGC TGGCCGCAGC TGTCTTCACA AAGGATTTGG ACAAGGCCAA TTACCTGTCC 
CAGGCCCTCC AGGCGGGCAC TGTGTGGGTC AACTGCTATG ATGTGTTTGG AGCCCAGTCA 
CCCTTTGGTG GCTACAAGAT GTCGGGGAGT GGCCGGGAGT TGGGCGAGTA CGGGCTGCAG 
GCATACACTG AAGTGAAAAC TGTCACAGTC AAAGTGCCTC AGAAGAACTC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000681.2
CDS	97..1650
Translation	MLRAAARFGPRLGRRLLSAAATQAVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS

Target ORF information:

RefSeq Version	NM_000690.3
Organism	Homo sapiens(human)
Definition	Homo sapiens aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000690.3

ORF Insert Sequence:

ATGTTGCGCG CTGCCGCCCG CTTCGGGCCC CGCCTGGGCC GCCGCCTCTT GTCAGCCGCC 
GCCACCCAGG CCGTGCCTGC CCCCAACCAG CAGCCCGAGG TCTTCTGCAA CCAGATTTTC 
ATAAACAATG AATGGCACGA TGCCGTCAGC AGGAAAACAT TCCCCACCGT CAATCCGTCC 
ACTGGAGAGG TCATCTGTCA GGTAGCTGAA GGGGACAAGG AAGATGTGGA CAAGGCAGTG 
AAGGCCGCCC GGGCCGCCTT CCAGCTGGGC TCACCTTGGC GCCGCATGGA CGCATCACAC 
AGGGGCCGGC TGCTGAACCG CCTGGCCGAT CTGATCGAGC GGGACCGGAC CTACCTGGCG 
GCCTTGGAGA CCCTGGACAA TGGCAAGCCC TATGTCATCT CCTACCTGGT GGATTTGGAC 
ATGGTCCTCA AATGTCTCCG GTATTATGCC GGCTGGGCTG ATAAGTACCA CGGGAAAACC 
ATCCCCATTG ACGGAGACTT CTTCAGCTAC ACACGCCATG AACCTGTGGG GGTGTGCGGG 
CAGATCATTC CGTGGAATTT CCCGCTCCTG ATGCAAGCAT GGAAGCTGGG CCCAGCCTTG 
GCAACTGGAA ACGTGGTTGT GATGAAGGTA GCTGAGCAGA CACCCCTCAC CGCCCTCTAT 
GTGGCCAACC TGATCAAGGA GGCTGGCTTT CCCCCTGGTG TGGTCAACAT TGTGCCTGGA 
TTTGGCCCCA CGGCTGGGGC CGCCATTGCC TCCCATGAGG ATGTGGACAA AGTGGCATTC 
ACAGGCTCCA CTGAGATTGG CCGCGTAATC CAGGTTGCTG CTGGGAGCAG CAACCTCAAG 
AGAGTGACCT TGGAGCTGGG GGGGAAGAGC CCCAACATCA TCATGTCAGA TGCCGATATG 
GATTGGGCCG TGGAACAGGC CCACTTCGCC CTGTTCTTCA ACCAGGGCCA GTGCTGCTGT 
GCCGGCTCCC GGACCTTCGT GCAGGAGGAC ATCTATGATG AGTTTGTGGA GCGGAGCGTT 
GCCCGGGCCA AGTCTCGGGT GGTCGGGAAC CCCTTTGATA GCAAGACCGA GCAGGGGCCG 
CAGGTGGATG AAACTCAGTT TAAGAAGATC CTCGGCTACA TCAACACGGG GAAGCAAGAG 
GGGGCGAAGC TGCTGTGTGG TGGGGGCATT GCTGCTGACC GTGGTTACTT CATCCAGCCC 
ACTGTGTTTG GAGATGTGCA GGATGGCATG ACCATCGCCA AGGAGGAGAT CTTCGGGCCA 
GTGATGCAGA TCCTGAAGTT CAAGACCATA GAGGAGGTTG TTGGGAGAGC CAACAATTCC 
ACGTACGGGC TGGCCGCAGC TGTCTTCACA AAGGATTTGG ACAAGGCCAA TTACCTGTCC 
CAGGCCCTCC AGGCGGGCAC TGTGTGGGTC AACTGCTATG ATGTGTTTGG AGCCCAGTCA 
CCCTTTGGTG GCTACAAGAT GTCGGGGAGT GGCCGGGAGT TGGGCGAGTA CGGGCTGCAG 
GCATACACTG AAGTGAAAAC TGTCACAGTC AAAGTGCCTC AGAAGAACTC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALDH2 ( NM_000690.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000681.2 Homo sapiens aldehyde dehydrogenase 2 family member (ALDH2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23457
Clone ID Related Accession (Same CDS sequence)	NM_000690.3 , NM_000690.4
Accession Version	NM_000690.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	aldehyde dehydrogenase, mitochondrial isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC353712.1, BC002967.1, CB851683.1 and AC003029.5. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_000690.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.169202.1, SRR1803612.222503.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000261733.7/ ENSP00000261733.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTTGCGCG CTGCCGCCCG CTTCGGGCCC CGCCTGGGCC GCCGCCTCTT GTCAGCCGCC 
GCCACCCAGG CCGTGCCTGC CCCCAACCAG CAGCCCGAGG TCTTCTGCAA CCAGATTTTC 
ATAAACAATG AATGGCACGA TGCCGTCAGC AGGAAAACAT TCCCCACCGT CAATCCGTCC 
ACTGGAGAGG TCATCTGTCA GGTAGCTGAA GGGGACAAGG AAGATGTGGA CAAGGCAGTG 
AAGGCCGCCC GGGCCGCCTT CCAGCTGGGC TCACCTTGGC GCCGCATGGA CGCATCACAC 
AGGGGCCGGC TGCTGAACCG CCTGGCCGAT CTGATCGAGC GGGACCGGAC CTACCTGGCG 
GCCTTGGAGA CCCTGGACAA TGGCAAGCCC TATGTCATCT CCTACCTGGT GGATTTGGAC 
ATGGTCCTCA AATGTCTCCG GTATTATGCC GGCTGGGCTG ATAAGTACCA CGGGAAAACC 
ATCCCCATTG ACGGAGACTT CTTCAGCTAC ACACGCCATG AACCTGTGGG GGTGTGCGGG 
CAGATCATTC CGTGGAATTT CCCGCTCCTG ATGCAAGCAT GGAAGCTGGG CCCAGCCTTG 
GCAACTGGAA ACGTGGTTGT GATGAAGGTA GCTGAGCAGA CACCCCTCAC CGCCCTCTAT 
GTGGCCAACC TGATCAAGGA GGCTGGCTTT CCCCCTGGTG TGGTCAACAT TGTGCCTGGA 
TTTGGCCCCA CGGCTGGGGC CGCCATTGCC TCCCATGAGG ATGTGGACAA AGTGGCATTC 
ACAGGCTCCA CTGAGATTGG CCGCGTAATC CAGGTTGCTG CTGGGAGCAG CAACCTCAAG 
AGAGTGACCT TGGAGCTGGG GGGGAAGAGC CCCAACATCA TCATGTCAGA TGCCGATATG 
GATTGGGCCG TGGAACAGGC CCACTTCGCC CTGTTCTTCA ACCAGGGCCA GTGCTGCTGT 
GCCGGCTCCC GGACCTTCGT GCAGGAGGAC ATCTATGATG AGTTTGTGGA GCGGAGCGTT 
GCCCGGGCCA AGTCTCGGGT GGTCGGGAAC CCCTTTGATA GCAAGACCGA GCAGGGGCCG 
CAGGTGGATG AAACTCAGTT TAAGAAGATC CTCGGCTACA TCAACACGGG GAAGCAAGAG 
GGGGCGAAGC TGCTGTGTGG TGGGGGCATT GCTGCTGACC GTGGTTACTT CATCCAGCCC 
ACTGTGTTTG GAGATGTGCA GGATGGCATG ACCATCGCCA AGGAGGAGAT CTTCGGGCCA 
GTGATGCAGA TCCTGAAGTT CAAGACCATA GAGGAGGTTG TTGGGAGAGC CAACAATTCC 
ACGTACGGGC TGGCCGCAGC TGTCTTCACA AAGGATTTGG ACAAGGCCAA TTACCTGTCC 
CAGGCCCTCC AGGCGGGCAC TGTGTGGGTC AACTGCTATG ATGTGTTTGG AGCCCAGTCA 
CCCTTTGGTG GCTACAAGAT GTCGGGGAGT GGCCGGGAGT TGGGCGAGTA CGGGCTGCAG 
GCATACACTG AAGTGAAAAC TGTCACAGTC AAAGTGCCTC AGAAGAACTC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000681.2
CDS	51..1604
Translation	MLRAAARFGPRLGRRLLSAAATQAVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS

Target ORF information:

RefSeq Version	NM_000690.4
Organism	Homo sapiens(human)
Definition	Homo sapiens aldehyde dehydrogenase 2 family member (ALDH2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000690.4

ORF Insert Sequence:

ATGTTGCGCG CTGCCGCCCG CTTCGGGCCC CGCCTGGGCC GCCGCCTCTT GTCAGCCGCC 
GCCACCCAGG CCGTGCCTGC CCCCAACCAG CAGCCCGAGG TCTTCTGCAA CCAGATTTTC 
ATAAACAATG AATGGCACGA TGCCGTCAGC AGGAAAACAT TCCCCACCGT CAATCCGTCC 
ACTGGAGAGG TCATCTGTCA GGTAGCTGAA GGGGACAAGG AAGATGTGGA CAAGGCAGTG 
AAGGCCGCCC GGGCCGCCTT CCAGCTGGGC TCACCTTGGC GCCGCATGGA CGCATCACAC 
AGGGGCCGGC TGCTGAACCG CCTGGCCGAT CTGATCGAGC GGGACCGGAC CTACCTGGCG 
GCCTTGGAGA CCCTGGACAA TGGCAAGCCC TATGTCATCT CCTACCTGGT GGATTTGGAC 
ATGGTCCTCA AATGTCTCCG GTATTATGCC GGCTGGGCTG ATAAGTACCA CGGGAAAACC 
ATCCCCATTG ACGGAGACTT CTTCAGCTAC ACACGCCATG AACCTGTGGG GGTGTGCGGG 
CAGATCATTC CGTGGAATTT CCCGCTCCTG ATGCAAGCAT GGAAGCTGGG CCCAGCCTTG 
GCAACTGGAA ACGTGGTTGT GATGAAGGTA GCTGAGCAGA CACCCCTCAC CGCCCTCTAT 
GTGGCCAACC TGATCAAGGA GGCTGGCTTT CCCCCTGGTG TGGTCAACAT TGTGCCTGGA 
TTTGGCCCCA CGGCTGGGGC CGCCATTGCC TCCCATGAGG ATGTGGACAA AGTGGCATTC 
ACAGGCTCCA CTGAGATTGG CCGCGTAATC CAGGTTGCTG CTGGGAGCAG CAACCTCAAG 
AGAGTGACCT TGGAGCTGGG GGGGAAGAGC CCCAACATCA TCATGTCAGA TGCCGATATG 
GATTGGGCCG TGGAACAGGC CCACTTCGCC CTGTTCTTCA ACCAGGGCCA GTGCTGCTGT 
GCCGGCTCCC GGACCTTCGT GCAGGAGGAC ATCTATGATG AGTTTGTGGA GCGGAGCGTT 
GCCCGGGCCA AGTCTCGGGT GGTCGGGAAC CCCTTTGATA GCAAGACCGA GCAGGGGCCG 
CAGGTGGATG AAACTCAGTT TAAGAAGATC CTCGGCTACA TCAACACGGG GAAGCAAGAG 
GGGGCGAAGC TGCTGTGTGG TGGGGGCATT GCTGCTGACC GTGGTTACTT CATCCAGCCC 
ACTGTGTTTG GAGATGTGCA GGATGGCATG ACCATCGCCA AGGAGGAGAT CTTCGGGCCA 
GTGATGCAGA TCCTGAAGTT CAAGACCATA GAGGAGGTTG TTGGGAGAGC CAACAATTCC 
ACGTACGGGC TGGCCGCAGC TGTCTTCACA AAGGATTTGG ACAAGGCCAA TTACCTGTCC 
CAGGCCCTCC AGGCGGGCAC TGTGTGGGTC AACTGCTATG ATGTGTTTGG AGCCCAGTCA 
CCCTTTGGTG GCTACAAGAT GTCGGGGAGT GGCCGGGAGT TGGGCGAGTA CGGGCTGCAG 
GCATACACTG AAGTGAAAAC TGTCACAGTC AAAGTGCCTC AGAAGAACTC ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALDH2 ( NM_001204889.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001191818.1 Homo sapiens aldehyde dehydrogenase 2 family member (ALDH2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23602
Clone ID Related Accession (Same CDS sequence)	NM_001204889.1 , NM_001204889.2
Accession Version	NM_001204889.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1413bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	aldehyde dehydrogenase, mitochondrial isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC353712.1, AK301375.1, BC002967.1 and CB851683.1. Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 1, and encodes a shorter isoform (2), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.255690.1, SRR1803615.152846.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTTGCGCG CTGCCGCCCG CTTCGGGCCC CGCCTGGGCC GCCGCCTCTT GTCAGCCGCC 
GCCACCCAGG CCGTGCCTGC CCCCAACCAG CAGCCCGAGG TCTTCTGCAA CCAGATTTTC 
ATAAACAATG AATGGCACGA TGCCGTCAGC AGGAAAACAT TCCCCACCGT CAATCCGTCC 
ACTGGAGAGG TCATCTGTCA GGTAGCTGAA GGGGACAAGG CCTTGGAGAC CCTGGACAAT 
GGCAAGCCCT ATGTCATCTC CTACCTGGTG GATTTGGACA TGGTCCTCAA ATGTCTCCGG 
TATTATGCCG GCTGGGCTGA TAAGTACCAC GGGAAAACCA TCCCCATTGA CGGAGACTTC 
TTCAGCTACA CACGCCATGA ACCTGTGGGG GTGTGCGGGC AGATCATTCC GTGGAATTTC 
CCGCTCCTGA TGCAAGCATG GAAGCTGGGC CCAGCCTTGG CAACTGGAAA CGTGGTTGTG 
ATGAAGGTAG CTGAGCAGAC ACCCCTCACC GCCCTCTATG TGGCCAACCT GATCAAGGAG 
GCTGGCTTTC CCCCTGGTGT GGTCAACATT GTGCCTGGAT TTGGCCCCAC GGCTGGGGCC 
GCCATTGCCT CCCATGAGGA TGTGGACAAA GTGGCATTCA CAGGCTCCAC TGAGATTGGC 
CGCGTAATCC AGGTTGCTGC TGGGAGCAGC AACCTCAAGA GAGTGACCTT GGAGCTGGGG 
GGGAAGAGCC CCAACATCAT CATGTCAGAT GCCGATATGG ATTGGGCCGT GGAACAGGCC 
CACTTCGCCC TGTTCTTCAA CCAGGGCCAG TGCTGCTGTG CCGGCTCCCG GACCTTCGTG 
CAGGAGGACA TCTATGATGA GTTTGTGGAG CGGAGCGTTG CCCGGGCCAA GTCTCGGGTG 
GTCGGGAACC CCTTTGATAG CAAGACCGAG CAGGGGCCGC AGGTGGATGA AACTCAGTTT 
AAGAAGATCC TCGGCTACAT CAACACGGGG AAGCAAGAGG GGGCGAAGCT GCTGTGTGGT 
GGGGGCATTG CTGCTGACCG TGGTTACTTC ATCCAGCCCA CTGTGTTTGG AGATGTGCAG 
GATGGCATGA CCATCGCCAA GGAGGAGATC TTCGGGCCAG TGATGCAGAT CCTGAAGTTC 
AAGACCATAG AGGAGGTTGT TGGGAGAGCC AACAATTCCA CGTACGGGCT GGCCGCAGCT 
GTCTTCACAA AGGATTTGGA CAAGGCCAAT TACCTGTCCC AGGCCCTCCA GGCGGGCACT 
GTGTGGGTCA ACTGCTATGA TGTGTTTGGA GCCCAGTCAC CCTTTGGTGG CTACAAGATG 
TCGGGGAGTG GCCGGGAGTT GGGCGAGTAC GGGCTGCAGG CATACACTGA AGTGAAAACT 
GTCACAGTCA AAGTGCCTCA GAAGAACTCA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001191818.1
CDS	97..1509
Translation	MLRAAARFGPRLGRRLLSAAATQAVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS

Target ORF information:

RefSeq Version	NM_001204889.1
Organism	Homo sapiens(human)
Definition	Homo sapiens aldehyde dehydrogenase 2 family member (ALDH2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001204889.1

ORF Insert Sequence:

ATGTTGCGCG CTGCCGCCCG CTTCGGGCCC CGCCTGGGCC GCCGCCTCTT GTCAGCCGCC 
GCCACCCAGG CCGTGCCTGC CCCCAACCAG CAGCCCGAGG TCTTCTGCAA CCAGATTTTC 
ATAAACAATG AATGGCACGA TGCCGTCAGC AGGAAAACAT TCCCCACCGT CAATCCGTCC 
ACTGGAGAGG TCATCTGTCA GGTAGCTGAA GGGGACAAGG CCTTGGAGAC CCTGGACAAT 
GGCAAGCCCT ATGTCATCTC CTACCTGGTG GATTTGGACA TGGTCCTCAA ATGTCTCCGG 
TATTATGCCG GCTGGGCTGA TAAGTACCAC GGGAAAACCA TCCCCATTGA CGGAGACTTC 
TTCAGCTACA CACGCCATGA ACCTGTGGGG GTGTGCGGGC AGATCATTCC GTGGAATTTC 
CCGCTCCTGA TGCAAGCATG GAAGCTGGGC CCAGCCTTGG CAACTGGAAA CGTGGTTGTG 
ATGAAGGTAG CTGAGCAGAC ACCCCTCACC GCCCTCTATG TGGCCAACCT GATCAAGGAG 
GCTGGCTTTC CCCCTGGTGT GGTCAACATT GTGCCTGGAT TTGGCCCCAC GGCTGGGGCC 
GCCATTGCCT CCCATGAGGA TGTGGACAAA GTGGCATTCA CAGGCTCCAC TGAGATTGGC 
CGCGTAATCC AGGTTGCTGC TGGGAGCAGC AACCTCAAGA GAGTGACCTT GGAGCTGGGG 
GGGAAGAGCC CCAACATCAT CATGTCAGAT GCCGATATGG ATTGGGCCGT GGAACAGGCC 
CACTTCGCCC TGTTCTTCAA CCAGGGCCAG TGCTGCTGTG CCGGCTCCCG GACCTTCGTG 
CAGGAGGACA TCTATGATGA GTTTGTGGAG CGGAGCGTTG CCCGGGCCAA GTCTCGGGTG 
GTCGGGAACC CCTTTGATAG CAAGACCGAG CAGGGGCCGC AGGTGGATGA AACTCAGTTT 
AAGAAGATCC TCGGCTACAT CAACACGGGG AAGCAAGAGG GGGCGAAGCT GCTGTGTGGT 
GGGGGCATTG CTGCTGACCG TGGTTACTTC ATCCAGCCCA CTGTGTTTGG AGATGTGCAG 
GATGGCATGA CCATCGCCAA GGAGGAGATC TTCGGGCCAG TGATGCAGAT CCTGAAGTTC 
AAGACCATAG AGGAGGTTGT TGGGAGAGCC AACAATTCCA CGTACGGGCT GGCCGCAGCT 
GTCTTCACAA AGGATTTGGA CAAGGCCAAT TACCTGTCCC AGGCCCTCCA GGCGGGCACT 
GTGTGGGTCA ACTGCTATGA TGTGTTTGGA GCCCAGTCAC CCTTTGGTGG CTACAAGATG 
TCGGGGAGTG GCCGGGAGTT GGGCGAGTAC GGGCTGCAGG CATACACTGA AGTGAAAACT 
GTCACAGTCA AAGTGCCTCA GAAGAACTCA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALDH2 ( NM_001204889.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001191818.1 Homo sapiens aldehyde dehydrogenase 2 family member (ALDH2), transcript variant 2, mRNA.

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CloneID	OHu23602
Clone ID Related Accession (Same CDS sequence)	NM_001204889.1 , NM_001204889.2
Accession Version	NM_001204889.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1413bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	aldehyde dehydrogenase, mitochondrial isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC353712.1, AK301375.1, BC002967.1, CB851683.1 and AC003029.5. On May 31, 2019 this sequence version replaced NM_001204889.1. Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 1, and encodes a shorter isoform (2), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTTGCGCG CTGCCGCCCG CTTCGGGCCC CGCCTGGGCC GCCGCCTCTT GTCAGCCGCC 
GCCACCCAGG CCGTGCCTGC CCCCAACCAG CAGCCCGAGG TCTTCTGCAA CCAGATTTTC 
ATAAACAATG AATGGCACGA TGCCGTCAGC AGGAAAACAT TCCCCACCGT CAATCCGTCC 
ACTGGAGAGG TCATCTGTCA GGTAGCTGAA GGGGACAAGG CCTTGGAGAC CCTGGACAAT 
GGCAAGCCCT ATGTCATCTC CTACCTGGTG GATTTGGACA TGGTCCTCAA ATGTCTCCGG 
TATTATGCCG GCTGGGCTGA TAAGTACCAC GGGAAAACCA TCCCCATTGA CGGAGACTTC 
TTCAGCTACA CACGCCATGA ACCTGTGGGG GTGTGCGGGC AGATCATTCC GTGGAATTTC 
CCGCTCCTGA TGCAAGCATG GAAGCTGGGC CCAGCCTTGG CAACTGGAAA CGTGGTTGTG 
ATGAAGGTAG CTGAGCAGAC ACCCCTCACC GCCCTCTATG TGGCCAACCT GATCAAGGAG 
GCTGGCTTTC CCCCTGGTGT GGTCAACATT GTGCCTGGAT TTGGCCCCAC GGCTGGGGCC 
GCCATTGCCT CCCATGAGGA TGTGGACAAA GTGGCATTCA CAGGCTCCAC TGAGATTGGC 
CGCGTAATCC AGGTTGCTGC TGGGAGCAGC AACCTCAAGA GAGTGACCTT GGAGCTGGGG 
GGGAAGAGCC CCAACATCAT CATGTCAGAT GCCGATATGG ATTGGGCCGT GGAACAGGCC 
CACTTCGCCC TGTTCTTCAA CCAGGGCCAG TGCTGCTGTG CCGGCTCCCG GACCTTCGTG 
CAGGAGGACA TCTATGATGA GTTTGTGGAG CGGAGCGTTG CCCGGGCCAA GTCTCGGGTG 
GTCGGGAACC CCTTTGATAG CAAGACCGAG CAGGGGCCGC AGGTGGATGA AACTCAGTTT 
AAGAAGATCC TCGGCTACAT CAACACGGGG AAGCAAGAGG GGGCGAAGCT GCTGTGTGGT 
GGGGGCATTG CTGCTGACCG TGGTTACTTC ATCCAGCCCA CTGTGTTTGG AGATGTGCAG 
GATGGCATGA CCATCGCCAA GGAGGAGATC TTCGGGCCAG TGATGCAGAT CCTGAAGTTC 
AAGACCATAG AGGAGGTTGT TGGGAGAGCC AACAATTCCA CGTACGGGCT GGCCGCAGCT 
GTCTTCACAA AGGATTTGGA CAAGGCCAAT TACCTGTCCC AGGCCCTCCA GGCGGGCACT 
GTGTGGGTCA ACTGCTATGA TGTGTTTGGA GCCCAGTCAC CCTTTGGTGG CTACAAGATG 
TCGGGGAGTG GCCGGGAGTT GGGCGAGTAC GGGCTGCAGG CATACACTGA AGTGAAAACT 
GTCACAGTCA AAGTGCCTCA GAAGAACTCA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001191818.1
CDS	51..1463
Translation	MLRAAARFGPRLGRRLLSAAATQAVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS

Target ORF information:

RefSeq Version	NM_001204889.2
Organism	Homo sapiens(human)
Definition	Homo sapiens aldehyde dehydrogenase 2 family member (ALDH2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001204889.2

ORF Insert Sequence:

ATGTTGCGCG CTGCCGCCCG CTTCGGGCCC CGCCTGGGCC GCCGCCTCTT GTCAGCCGCC 
GCCACCCAGG CCGTGCCTGC CCCCAACCAG CAGCCCGAGG TCTTCTGCAA CCAGATTTTC 
ATAAACAATG AATGGCACGA TGCCGTCAGC AGGAAAACAT TCCCCACCGT CAATCCGTCC 
ACTGGAGAGG TCATCTGTCA GGTAGCTGAA GGGGACAAGG CCTTGGAGAC CCTGGACAAT 
GGCAAGCCCT ATGTCATCTC CTACCTGGTG GATTTGGACA TGGTCCTCAA ATGTCTCCGG 
TATTATGCCG GCTGGGCTGA TAAGTACCAC GGGAAAACCA TCCCCATTGA CGGAGACTTC 
TTCAGCTACA CACGCCATGA ACCTGTGGGG GTGTGCGGGC AGATCATTCC GTGGAATTTC 
CCGCTCCTGA TGCAAGCATG GAAGCTGGGC CCAGCCTTGG CAACTGGAAA CGTGGTTGTG 
ATGAAGGTAG CTGAGCAGAC ACCCCTCACC GCCCTCTATG TGGCCAACCT GATCAAGGAG 
GCTGGCTTTC CCCCTGGTGT GGTCAACATT GTGCCTGGAT TTGGCCCCAC GGCTGGGGCC 
GCCATTGCCT CCCATGAGGA TGTGGACAAA GTGGCATTCA CAGGCTCCAC TGAGATTGGC 
CGCGTAATCC AGGTTGCTGC TGGGAGCAGC AACCTCAAGA GAGTGACCTT GGAGCTGGGG 
GGGAAGAGCC CCAACATCAT CATGTCAGAT GCCGATATGG ATTGGGCCGT GGAACAGGCC 
CACTTCGCCC TGTTCTTCAA CCAGGGCCAG TGCTGCTGTG CCGGCTCCCG GACCTTCGTG 
CAGGAGGACA TCTATGATGA GTTTGTGGAG CGGAGCGTTG CCCGGGCCAA GTCTCGGGTG 
GTCGGGAACC CCTTTGATAG CAAGACCGAG CAGGGGCCGC AGGTGGATGA AACTCAGTTT 
AAGAAGATCC TCGGCTACAT CAACACGGGG AAGCAAGAGG GGGCGAAGCT GCTGTGTGGT 
GGGGGCATTG CTGCTGACCG TGGTTACTTC ATCCAGCCCA CTGTGTTTGG AGATGTGCAG 
GATGGCATGA CCATCGCCAA GGAGGAGATC TTCGGGCCAG TGATGCAGAT CCTGAAGTTC 
AAGACCATAG AGGAGGTTGT TGGGAGAGCC AACAATTCCA CGTACGGGCT GGCCGCAGCT 
GTCTTCACAA AGGATTTGGA CAAGGCCAAT TACCTGTCCC AGGCCCTCCA GGCGGGCACT 
GTGTGGGTCA ACTGCTATGA TGTGTTTGGA GCCCAGTCAC CCTTTGGTGG CTACAAGATG 
TCGGGGAGTG GCCGGGAGTT GGGCGAGTAC GGGCTGCAGG CATACACTGA AGTGAAAACT 
GTCACAGTCA AAGTGCCTCA GAAGAACTCA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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ALDH2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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