ALB cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ALB
Entrez Gene ID	213
Full Name	albumin
Synonyms	HSA,PRO0883,PRO0903,PRO1341
General protein information	Preferred Names albumin Names serum albumin
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q13.3
Summary	This gene encodes the most abundant protein in human blood. This protein functions in the regulation of blood plasma colloid osmotic pressure and acts as a carrier protein for a wide range of endogenous molecules including hormones, fatty acids, and metabolites, as well as exogenous drugs. Additionally, this protein exhibits an esterase-like activity with broad substrate specificity. The encoded preproprotein is proteolytically processed to generate the mature protein. A peptide derived from this protein, EPI-X4, is an endogenous inhibitor of the CXCR4 chemokine receptor. [provided by RefSeq, Jul 2016].
Disorder MIM:	103600
Disorder Html:	Analbuminemia, 616000 (3); [Dysalbuminemic hyperthyroxinemia], 615999 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_000477.7	NP_000468.1	serum albumin preproprotein
NM_000477.5	NP_000468.1	serum albumin preproprotein
NM_000477.6	NP_000468.1	serum albumin preproprotein

Pathways from BioSystems

Homologies

	ALB	XP_001103956.1
Bos taurus (cattle)	ALB	NP_851335.1
Xenopus tropicalis (tropical clawed frog)	cars2	NP_001004887.2
Pan troglodytes (chimpanzee)	ALB	XP_517233.3
Homo sapiens (human)	ALB	NP_000468.1
Mus musculus (house mouse)	Alb	NP_033784.2
Rattus norvegicus (Norway rat)	Alb	NP_599153.2
Gallus gallus (chicken)	ALB	NP_990592.1
Canis lupus familiaris (dog)	ALB	NP_001003026.1

Gene Ontology
Bibliography

Related articles in PubMed

Bilirubin Albumin Binding and Unbound Unconjugated Hyperbilirubinemia in Premature Infants.
Amin SB, Wang H
The Journal of pediatrics19247-52(2018 Jan)

Physiological serum copper concentrations found in malignancies cause unfolding induced aggregation of human serum albumin in vitro.
Rizvi A, Furkan M, Naseem I
Archives of biochemistry and biophysics63671-78(2017 Dec)

Proteolytic processing of human serum albumin generates EPI-X4, an endogenous antagonist of CXCR4.
Zirafi O, Hermann PC, M?nch J
Journal of leukocyte biology99(6)863-8(2016 06)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

C-reactive protein-to-albumin ratio is a promising predictor of survival and recurrence in patients with rectal cancer treated by chemoradiotherapy followed by surgery.
Title: Clinical Significance of C-Reactive Protein-to-Albumin Ratio with Rectal Cancer Patient Undergoing Chemoradiotherapy Followed by Surgery.

These results provide an unprecedented view of how albumin interacts with Abeta and illustrate the potential of dark-state exchange saturation transfer NMR in mapping the interactions between amyloid-inhibitory proteins and amyloidogenic peptides.
Title: Atomic-resolution map of the interactions between an amyloid inhibitor protein and amyloid ? (A?) peptides in the monomer and protofibril states.

Data suggest that, unlike albumin with low FcRn-binding affinity, albumin with high FcRn-binding affinity (due to genetic variation/genetic engineering) is directed less to lysosomes and more to endosomes, suggestive of FcRn-directed albumin salvage from lysosomal degradation. (FcRn = neonatal Fc receptor)
Title: Direct demonstration of a neonatal Fc receptor (FcRn)-driven endosomal sorting pathway for cellular recycling of albumin.

Intensity of systemic inflammation was assessed at all time points with C-reactive protein and albumin as prognostic covariates for overall survival in an extended Cox regression model.time-dependent effects are a prominent feature of intensity of systemic inflammation, a powerful prognostic biomarker for metastatic renal cell carcinoma.
Title: Time-dependent effects of prognostic biomarkers of systemic inflammation in patients with metastatic renal cell carcinoma.

results indicate that in addition to its role as a monitor of systemic inflammation, albumin may have a direct role in hepatocellular carcinoma growth inhibition, either through modulation of alpha-fetoprotein or through its actions on growth-controlling kinases
Title: Role of Albumin in Growth Inhibition in Hepatocellular Carcinoma.

The following ALB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ALB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18744	NM_000477.7 Latest version!	Homo sapiens albumin (ALB), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu18744	NM_000477.5	Homo sapiens albumin (ALB), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu18744	NM_000477.6	Homo sapiens albumin (ALB), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ALB ( NM_000477.7 ) cDNA ORF clone, Homo sapiens(human) -> NP_000468.1 Homo sapiens albumin (ALB), mRNA.

Price & Availability↑

CloneID	OHu18744
Clone ID Related Accession (Same CDS sequence)	NM_000477.7 , NM_000477.5 , NM_000477.6
Accession Version	NM_000477.7 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1830bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	serum albumin preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB186399.1, DA642320.1, DQ986150.1, N53869.1 and AC108157.3. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_000477.6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC036003.1, SRR5189664.159361.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology MANE Ensembl match :: ENST00000295897.9/ ENSP00000295897.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGTGGG TAACCTTTAT TTCCCTTCTT TTTCTCTTTA GCTCGGCTTA TTCCAGGGGT 
GTGTTTCGTC GAGATGCACA CAAGAGTGAG GTTGCTCATC GGTTTAAAGA TTTGGGAGAA 
GAAAATTTCA AAGCCTTGGT GTTGATTGCC TTTGCTCAGT ATCTTCAGCA GTGTCCATTT 
GAAGATCATG TAAAATTAGT GAATGAAGTA ACTGAATTTG CAAAAACATG TGTTGCTGAT 
GAGTCAGCTG AAAATTGTGA CAAATCACTT CATACCCTTT TTGGAGACAA ATTATGCACA 
GTTGCAACTC TTCGTGAAAC CTATGGTGAA ATGGCTGACT GCTGTGCAAA ACAAGAACCT 
GAGAGAAATG AATGCTTCTT GCAACACAAA GATGACAACC CAAACCTCCC CCGATTGGTG 
AGACCAGAGG TTGATGTGAT GTGCACTGCT TTTCATGACA ATGAAGAGAC ATTTTTGAAA 
AAATACTTAT ATGAAATTGC CAGAAGACAT CCTTACTTTT ATGCCCCGGA ACTCCTTTTC 
TTTGCTAAAA GGTATAAAGC TGCTTTTACA GAATGTTGCC AAGCTGCTGA TAAAGCTGCC 
TGCCTGTTGC CAAAGCTCGA TGAACTTCGG GATGAAGGGA AGGCTTCGTC TGCCAAACAG 
AGACTCAAGT GTGCCAGTCT CCAAAAATTT GGAGAAAGAG CTTTCAAAGC ATGGGCAGTA 
GCTCGCCTGA GCCAGAGATT TCCCAAAGCT GAGTTTGCAG AAGTTTCCAA GTTAGTGACA 
GATCTTACCA AAGTCCACAC GGAATGCTGC CATGGAGATC TGCTTGAATG TGCTGATGAC 
AGGGCGGACC TTGCCAAGTA TATCTGTGAA AATCAAGATT CGATCTCCAG TAAACTGAAG 
GAATGCTGTG AAAAACCTCT GTTGGAAAAA TCCCACTGCA TTGCCGAAGT GGAAAATGAT 
GAGATGCCTG CTGACTTGCC TTCATTAGCT GCTGATTTTG TTGAAAGTAA GGATGTTTGC 
AAAAACTATG CTGAGGCAAA GGATGTCTTC CTGGGCATGT TTTTGTATGA ATATGCAAGA 
AGGCATCCTG ATTACTCTGT CGTGCTGCTG CTGAGACTTG CCAAGACATA TGAAACCACT 
CTAGAGAAGT GCTGTGCCGC TGCAGATCCT CATGAATGCT ATGCCAAAGT GTTCGATGAA 
TTTAAACCTC TTGTGGAAGA GCCTCAGAAT TTAATCAAAC AAAATTGTGA GCTTTTTGAG 
CAGCTTGGAG AGTACAAATT CCAGAATGCG CTATTAGTTC GTTACACCAA GAAAGTACCC 
CAAGTGTCAA CTCCAACTCT TGTAGAGGTC TCAAGAAACC TAGGAAAAGT GGGCAGCAAA 
TGTTGTAAAC ATCCTGAAGC AAAAAGAATG CCCTGTGCAG AAGACTATCT ATCCGTGGTC 
CTGAACCAGT TATGTGTGTT GCATGAGAAA ACGCCAGTAA GTGACAGAGT CACCAAATGC 
TGCACAGAAT CCTTGGTGAA CAGGCGACCA TGCTTTTCAG CTCTGGAAGT CGATGAAACA 
TACGTTCCCA AAGAGTTTAA TGCTGAAACA TTCACCTTCC ATGCAGATAT ATGCACACTT 
TCTGAGAAGG AGAGACAAAT CAAGAAACAA ACTGCACTTG TTGAGCTCGT GAAACACAAG 
CCCAAGGCAA CAAAAGAGCA ACTGAAAGCT GTTATGGATG ATTTCGCAGC TTTTGTAGAG 
AAGTGCTGCA AGGCTGACGA TAAGGAGACC TGCTTTGCCG AGGAGGGTAA AAAACTTGTT 
GCTGCAAGTC AAGCTGCCTT AGGCTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000468.1
CDS	42..1871
Translation	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL

Target ORF information:

RefSeq Version	NM_000477.7
Organism	Homo sapiens(human)
Definition	Homo sapiens albumin (ALB), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000477.7

ORF Insert Sequence:

ATGAAGTGGG TAACCTTTAT TTCCCTTCTT TTTCTCTTTA GCTCGGCTTA TTCCAGGGGT 
GTGTTTCGTC GAGATGCACA CAAGAGTGAG GTTGCTCATC GGTTTAAAGA TTTGGGAGAA 
GAAAATTTCA AAGCCTTGGT GTTGATTGCC TTTGCTCAGT ATCTTCAGCA GTGTCCATTT 
GAAGATCATG TAAAATTAGT GAATGAAGTA ACTGAATTTG CAAAAACATG TGTTGCTGAT 
GAGTCAGCTG AAAATTGTGA CAAATCACTT CATACCCTTT TTGGAGACAA ATTATGCACA 
GTTGCAACTC TTCGTGAAAC CTATGGTGAA ATGGCTGACT GCTGTGCAAA ACAAGAACCT 
GAGAGAAATG AATGCTTCTT GCAACACAAA GATGACAACC CAAACCTCCC CCGATTGGTG 
AGACCAGAGG TTGATGTGAT GTGCACTGCT TTTCATGACA ATGAAGAGAC ATTTTTGAAA 
AAATACTTAT ATGAAATTGC CAGAAGACAT CCTTACTTTT ATGCCCCGGA ACTCCTTTTC 
TTTGCTAAAA GGTATAAAGC TGCTTTTACA GAATGTTGCC AAGCTGCTGA TAAAGCTGCC 
TGCCTGTTGC CAAAGCTCGA TGAACTTCGG GATGAAGGGA AGGCTTCGTC TGCCAAACAG 
AGACTCAAGT GTGCCAGTCT CCAAAAATTT GGAGAAAGAG CTTTCAAAGC ATGGGCAGTA 
GCTCGCCTGA GCCAGAGATT TCCCAAAGCT GAGTTTGCAG AAGTTTCCAA GTTAGTGACA 
GATCTTACCA AAGTCCACAC GGAATGCTGC CATGGAGATC TGCTTGAATG TGCTGATGAC 
AGGGCGGACC TTGCCAAGTA TATCTGTGAA AATCAAGATT CGATCTCCAG TAAACTGAAG 
GAATGCTGTG AAAAACCTCT GTTGGAAAAA TCCCACTGCA TTGCCGAAGT GGAAAATGAT 
GAGATGCCTG CTGACTTGCC TTCATTAGCT GCTGATTTTG TTGAAAGTAA GGATGTTTGC 
AAAAACTATG CTGAGGCAAA GGATGTCTTC CTGGGCATGT TTTTGTATGA ATATGCAAGA 
AGGCATCCTG ATTACTCTGT CGTGCTGCTG CTGAGACTTG CCAAGACATA TGAAACCACT 
CTAGAGAAGT GCTGTGCCGC TGCAGATCCT CATGAATGCT ATGCCAAAGT GTTCGATGAA 
TTTAAACCTC TTGTGGAAGA GCCTCAGAAT TTAATCAAAC AAAATTGTGA GCTTTTTGAG 
CAGCTTGGAG AGTACAAATT CCAGAATGCG CTATTAGTTC GTTACACCAA GAAAGTACCC 
CAAGTGTCAA CTCCAACTCT TGTAGAGGTC TCAAGAAACC TAGGAAAAGT GGGCAGCAAA 
TGTTGTAAAC ATCCTGAAGC AAAAAGAATG CCCTGTGCAG AAGACTATCT ATCCGTGGTC 
CTGAACCAGT TATGTGTGTT GCATGAGAAA ACGCCAGTAA GTGACAGAGT CACCAAATGC 
TGCACAGAAT CCTTGGTGAA CAGGCGACCA TGCTTTTCAG CTCTGGAAGT CGATGAAACA 
TACGTTCCCA AAGAGTTTAA TGCTGAAACA TTCACCTTCC ATGCAGATAT ATGCACACTT 
TCTGAGAAGG AGAGACAAAT CAAGAAACAA ACTGCACTTG TTGAGCTCGT GAAACACAAG 
CCCAAGGCAA CAAAAGAGCA ACTGAAAGCT GTTATGGATG ATTTCGCAGC TTTTGTAGAG 
AAGTGCTGCA AGGCTGACGA TAAGGAGACC TGCTTTGCCG AGGAGGGTAA AAAACTTGTT 
GCTGCAAGTC AAGCTGCCTT AGGCTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALB ( NM_000477.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_000468.1 Homo sapiens albumin (ALB), mRNA.

Price & Availability↑

CloneID	OHu18744
Clone ID Related Accession (Same CDS sequence)	NM_000477.7 , NM_000477.5 , NM_000477.6
Accession Version	NM_000477.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1830bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	serum albumin preproprotein
Comment

ATGAAGTGGG TAACCTTTAT TTCCCTTCTT TTTCTCTTTA GCTCGGCTTA TTCCAGGGGT 
GTGTTTCGTC GAGATGCACA CAAGAGTGAG GTTGCTCATC GGTTTAAAGA TTTGGGAGAA 
GAAAATTTCA AAGCCTTGGT GTTGATTGCC TTTGCTCAGT ATCTTCAGCA GTGTCCATTT 
GAAGATCATG TAAAATTAGT GAATGAAGTA ACTGAATTTG CAAAAACATG TGTTGCTGAT 
GAGTCAGCTG AAAATTGTGA CAAATCACTT CATACCCTTT TTGGAGACAA ATTATGCACA 
GTTGCAACTC TTCGTGAAAC CTATGGTGAA ATGGCTGACT GCTGTGCAAA ACAAGAACCT 
GAGAGAAATG AATGCTTCTT GCAACACAAA GATGACAACC CAAACCTCCC CCGATTGGTG 
AGACCAGAGG TTGATGTGAT GTGCACTGCT TTTCATGACA ATGAAGAGAC ATTTTTGAAA 
AAATACTTAT ATGAAATTGC CAGAAGACAT CCTTACTTTT ATGCCCCGGA ACTCCTTTTC 
TTTGCTAAAA GGTATAAAGC TGCTTTTACA GAATGTTGCC AAGCTGCTGA TAAAGCTGCC 
TGCCTGTTGC CAAAGCTCGA TGAACTTCGG GATGAAGGGA AGGCTTCGTC TGCCAAACAG 
AGACTCAAGT GTGCCAGTCT CCAAAAATTT GGAGAAAGAG CTTTCAAAGC ATGGGCAGTA 
GCTCGCCTGA GCCAGAGATT TCCCAAAGCT GAGTTTGCAG AAGTTTCCAA GTTAGTGACA 
GATCTTACCA AAGTCCACAC GGAATGCTGC CATGGAGATC TGCTTGAATG TGCTGATGAC 
AGGGCGGACC TTGCCAAGTA TATCTGTGAA AATCAAGATT CGATCTCCAG TAAACTGAAG 
GAATGCTGTG AAAAACCTCT GTTGGAAAAA TCCCACTGCA TTGCCGAAGT GGAAAATGAT 
GAGATGCCTG CTGACTTGCC TTCATTAGCT GCTGATTTTG TTGAAAGTAA GGATGTTTGC 
AAAAACTATG CTGAGGCAAA GGATGTCTTC CTGGGCATGT TTTTGTATGA ATATGCAAGA 
AGGCATCCTG ATTACTCTGT CGTGCTGCTG CTGAGACTTG CCAAGACATA TGAAACCACT 
CTAGAGAAGT GCTGTGCCGC TGCAGATCCT CATGAATGCT ATGCCAAAGT GTTCGATGAA 
TTTAAACCTC TTGTGGAAGA GCCTCAGAAT TTAATCAAAC AAAATTGTGA GCTTTTTGAG 
CAGCTTGGAG AGTACAAATT CCAGAATGCG CTATTAGTTC GTTACACCAA GAAAGTACCC 
CAAGTGTCAA CTCCAACTCT TGTAGAGGTC TCAAGAAACC TAGGAAAAGT GGGCAGCAAA 
TGTTGTAAAC ATCCTGAAGC AAAAAGAATG CCCTGTGCAG AAGACTATCT ATCCGTGGTC 
CTGAACCAGT TATGTGTGTT GCATGAGAAA ACGCCAGTAA GTGACAGAGT CACCAAATGC 
TGCACAGAAT CCTTGGTGAA CAGGCGACCA TGCTTTTCAG CTCTGGAAGT CGATGAAACA 
TACGTTCCCA AAGAGTTTAA TGCTGAAACA TTCACCTTCC ATGCAGATAT ATGCACACTT 
TCTGAGAAGG AGAGACAAAT CAAGAAACAA ACTGCACTTG TTGAGCTCGT GAAACACAAG 
CCCAAGGCAA CAAAAGAGCA ACTGAAAGCT GTTATGGATG ATTTCGCAGC TTTTGTAGAG 
AAGTGCTGCA AGGCTGACGA TAAGGAGACC TGCTTTGCCG AGGAGGGTAA AAAACTTGTT 
GCTGCAAGTC AAGCTGCCTT AGGCTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_000468.1

Translation

MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL

Target ORF information:

RefSeq Version	NM_000477.5
Organism	Homo sapiens(Human)
Definition	Homo sapiens albumin (ALB), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000477.5

ORF Insert Sequence:

ATGAAGTGGG TAACCTTTAT TTCCCTTCTT TTTCTCTTTA GCTCGGCTTA TTCCAGGGGT 
GTGTTTCGTC GAGATGCACA CAAGAGTGAG GTTGCTCATC GGTTTAAAGA TTTGGGAGAA 
GAAAATTTCA AAGCCTTGGT GTTGATTGCC TTTGCTCAGT ATCTTCAGCA GTGTCCATTT 
GAAGATCATG TAAAATTAGT GAATGAAGTA ACTGAATTTG CAAAAACATG TGTTGCTGAT 
GAGTCAGCTG AAAATTGTGA CAAATCACTT CATACCCTTT TTGGAGACAA ATTATGCACA 
GTTGCAACTC TTCGTGAAAC CTATGGTGAA ATGGCTGACT GCTGTGCAAA ACAAGAACCT 
GAGAGAAATG AATGCTTCTT GCAACACAAA GATGACAACC CAAACCTCCC CCGATTGGTG 
AGACCAGAGG TTGATGTGAT GTGCACTGCT TTTCATGACA ATGAAGAGAC ATTTTTGAAA 
AAATACTTAT ATGAAATTGC CAGAAGACAT CCTTACTTTT ATGCCCCGGA ACTCCTTTTC 
TTTGCTAAAA GGTATAAAGC TGCTTTTACA GAATGTTGCC AAGCTGCTGA TAAAGCTGCC 
TGCCTGTTGC CAAAGCTCGA TGAACTTCGG GATGAAGGGA AGGCTTCGTC TGCCAAACAG 
AGACTCAAGT GTGCCAGTCT CCAAAAATTT GGAGAAAGAG CTTTCAAAGC ATGGGCAGTA 
GCTCGCCTGA GCCAGAGATT TCCCAAAGCT GAGTTTGCAG AAGTTTCCAA GTTAGTGACA 
GATCTTACCA AAGTCCACAC GGAATGCTGC CATGGAGATC TGCTTGAATG TGCTGATGAC 
AGGGCGGACC TTGCCAAGTA TATCTGTGAA AATCAAGATT CGATCTCCAG TAAACTGAAG 
GAATGCTGTG AAAAACCTCT GTTGGAAAAA TCCCACTGCA TTGCCGAAGT GGAAAATGAT 
GAGATGCCTG CTGACTTGCC TTCATTAGCT GCTGATTTTG TTGAAAGTAA GGATGTTTGC 
AAAAACTATG CTGAGGCAAA GGATGTCTTC CTGGGCATGT TTTTGTATGA ATATGCAAGA 
AGGCATCCTG ATTACTCTGT CGTGCTGCTG CTGAGACTTG CCAAGACATA TGAAACCACT 
CTAGAGAAGT GCTGTGCCGC TGCAGATCCT CATGAATGCT ATGCCAAAGT GTTCGATGAA 
TTTAAACCTC TTGTGGAAGA GCCTCAGAAT TTAATCAAAC AAAATTGTGA GCTTTTTGAG 
CAGCTTGGAG AGTACAAATT CCAGAATGCG CTATTAGTTC GTTACACCAA GAAAGTACCC 
CAAGTGTCAA CTCCAACTCT TGTAGAGGTC TCAAGAAACC TAGGAAAAGT GGGCAGCAAA 
TGTTGTAAAC ATCCTGAAGC AAAAAGAATG CCCTGTGCAG AAGACTATCT ATCCGTGGTC 
CTGAACCAGT TATGTGTGTT GCATGAGAAA ACGCCAGTAA GTGACAGAGT CACCAAATGC 
TGCACAGAAT CCTTGGTGAA CAGGCGACCA TGCTTTTCAG CTCTGGAAGT CGATGAAACA 
TACGTTCCCA AAGAGTTTAA TGCTGAAACA TTCACCTTCC ATGCAGATAT ATGCACACTT 
TCTGAGAAGG AGAGACAAAT CAAGAAACAA ACTGCACTTG TTGAGCTCGT GAAACACAAG 
CCCAAGGCAA CAAAAGAGCA ACTGAAAGCT GTTATGGATG ATTTCGCAGC TTTTGTAGAG 
AAGTGCTGCA AGGCTGACGA TAAGGAGACC TGCTTTGCCG AGGAGGGTAA AAAACTTGTT 
GCTGCAAGTC AAGCTGCCTT AGGCTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ALB ( NM_000477.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_000468.1 Homo sapiens albumin (ALB), mRNA.

Price & Availability↑

CloneID	OHu18744
Clone ID Related Accession (Same CDS sequence)	NM_000477.7 , NM_000477.5 , NM_000477.6
Accession Version	NM_000477.6	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1830bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-31
Organism	Homo sapiens(human)
Product	serum albumin preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB186399.1, DA642320.1, DQ986150.1, N53869.1 and AC108157.3. This sequence is a reference standard in the RefSeqGene project. On Jul 25, 2016 this sequence version replaced NM_000477.5. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. COMPLETENESS: full length.

ATGAAGTGGG TAACCTTTAT TTCCCTTCTT TTTCTCTTTA GCTCGGCTTA TTCCAGGGGT 
GTGTTTCGTC GAGATGCACA CAAGAGTGAG GTTGCTCATC GGTTTAAAGA TTTGGGAGAA 
GAAAATTTCA AAGCCTTGGT GTTGATTGCC TTTGCTCAGT ATCTTCAGCA GTGTCCATTT 
GAAGATCATG TAAAATTAGT GAATGAAGTA ACTGAATTTG CAAAAACATG TGTTGCTGAT 
GAGTCAGCTG AAAATTGTGA CAAATCACTT CATACCCTTT TTGGAGACAA ATTATGCACA 
GTTGCAACTC TTCGTGAAAC CTATGGTGAA ATGGCTGACT GCTGTGCAAA ACAAGAACCT 
GAGAGAAATG AATGCTTCTT GCAACACAAA GATGACAACC CAAACCTCCC CCGATTGGTG 
AGACCAGAGG TTGATGTGAT GTGCACTGCT TTTCATGACA ATGAAGAGAC ATTTTTGAAA 
AAATACTTAT ATGAAATTGC CAGAAGACAT CCTTACTTTT ATGCCCCGGA ACTCCTTTTC 
TTTGCTAAAA GGTATAAAGC TGCTTTTACA GAATGTTGCC AAGCTGCTGA TAAAGCTGCC 
TGCCTGTTGC CAAAGCTCGA TGAACTTCGG GATGAAGGGA AGGCTTCGTC TGCCAAACAG 
AGACTCAAGT GTGCCAGTCT CCAAAAATTT GGAGAAAGAG CTTTCAAAGC ATGGGCAGTA 
GCTCGCCTGA GCCAGAGATT TCCCAAAGCT GAGTTTGCAG AAGTTTCCAA GTTAGTGACA 
GATCTTACCA AAGTCCACAC GGAATGCTGC CATGGAGATC TGCTTGAATG TGCTGATGAC 
AGGGCGGACC TTGCCAAGTA TATCTGTGAA AATCAAGATT CGATCTCCAG TAAACTGAAG 
GAATGCTGTG AAAAACCTCT GTTGGAAAAA TCCCACTGCA TTGCCGAAGT GGAAAATGAT 
GAGATGCCTG CTGACTTGCC TTCATTAGCT GCTGATTTTG TTGAAAGTAA GGATGTTTGC 
AAAAACTATG CTGAGGCAAA GGATGTCTTC CTGGGCATGT TTTTGTATGA ATATGCAAGA 
AGGCATCCTG ATTACTCTGT CGTGCTGCTG CTGAGACTTG CCAAGACATA TGAAACCACT 
CTAGAGAAGT GCTGTGCCGC TGCAGATCCT CATGAATGCT ATGCCAAAGT GTTCGATGAA 
TTTAAACCTC TTGTGGAAGA GCCTCAGAAT TTAATCAAAC AAAATTGTGA GCTTTTTGAG 
CAGCTTGGAG AGTACAAATT CCAGAATGCG CTATTAGTTC GTTACACCAA GAAAGTACCC 
CAAGTGTCAA CTCCAACTCT TGTAGAGGTC TCAAGAAACC TAGGAAAAGT GGGCAGCAAA 
TGTTGTAAAC ATCCTGAAGC AAAAAGAATG CCCTGTGCAG AAGACTATCT ATCCGTGGTC 
CTGAACCAGT TATGTGTGTT GCATGAGAAA ACGCCAGTAA GTGACAGAGT CACCAAATGC 
TGCACAGAAT CCTTGGTGAA CAGGCGACCA TGCTTTTCAG CTCTGGAAGT CGATGAAACA 
TACGTTCCCA AAGAGTTTAA TGCTGAAACA TTCACCTTCC ATGCAGATAT ATGCACACTT 
TCTGAGAAGG AGAGACAAAT CAAGAAACAA ACTGCACTTG TTGAGCTCGT GAAACACAAG 
CCCAAGGCAA CAAAAGAGCA ACTGAAAGCT GTTATGGATG ATTTCGCAGC TTTTGTAGAG 
AAGTGCTGCA AGGCTGACGA TAAGGAGACC TGCTTTGCCG AGGAGGGTAA AAAACTTGTT 
GCTGCAAGTC AAGCTGCCTT AGGCTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000468.1
CDS	90..1919
Translation	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL

Target ORF information:

RefSeq Version	NM_000477.6
Organism	Homo sapiens(human)
Definition	Homo sapiens albumin (ALB), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000477.6

ORF Insert Sequence:

ATGAAGTGGG TAACCTTTAT TTCCCTTCTT TTTCTCTTTA GCTCGGCTTA TTCCAGGGGT 
GTGTTTCGTC GAGATGCACA CAAGAGTGAG GTTGCTCATC GGTTTAAAGA TTTGGGAGAA 
GAAAATTTCA AAGCCTTGGT GTTGATTGCC TTTGCTCAGT ATCTTCAGCA GTGTCCATTT 
GAAGATCATG TAAAATTAGT GAATGAAGTA ACTGAATTTG CAAAAACATG TGTTGCTGAT 
GAGTCAGCTG AAAATTGTGA CAAATCACTT CATACCCTTT TTGGAGACAA ATTATGCACA 
GTTGCAACTC TTCGTGAAAC CTATGGTGAA ATGGCTGACT GCTGTGCAAA ACAAGAACCT 
GAGAGAAATG AATGCTTCTT GCAACACAAA GATGACAACC CAAACCTCCC CCGATTGGTG 
AGACCAGAGG TTGATGTGAT GTGCACTGCT TTTCATGACA ATGAAGAGAC ATTTTTGAAA 
AAATACTTAT ATGAAATTGC CAGAAGACAT CCTTACTTTT ATGCCCCGGA ACTCCTTTTC 
TTTGCTAAAA GGTATAAAGC TGCTTTTACA GAATGTTGCC AAGCTGCTGA TAAAGCTGCC 
TGCCTGTTGC CAAAGCTCGA TGAACTTCGG GATGAAGGGA AGGCTTCGTC TGCCAAACAG 
AGACTCAAGT GTGCCAGTCT CCAAAAATTT GGAGAAAGAG CTTTCAAAGC ATGGGCAGTA 
GCTCGCCTGA GCCAGAGATT TCCCAAAGCT GAGTTTGCAG AAGTTTCCAA GTTAGTGACA 
GATCTTACCA AAGTCCACAC GGAATGCTGC CATGGAGATC TGCTTGAATG TGCTGATGAC 
AGGGCGGACC TTGCCAAGTA TATCTGTGAA AATCAAGATT CGATCTCCAG TAAACTGAAG 
GAATGCTGTG AAAAACCTCT GTTGGAAAAA TCCCACTGCA TTGCCGAAGT GGAAAATGAT 
GAGATGCCTG CTGACTTGCC TTCATTAGCT GCTGATTTTG TTGAAAGTAA GGATGTTTGC 
AAAAACTATG CTGAGGCAAA GGATGTCTTC CTGGGCATGT TTTTGTATGA ATATGCAAGA 
AGGCATCCTG ATTACTCTGT CGTGCTGCTG CTGAGACTTG CCAAGACATA TGAAACCACT 
CTAGAGAAGT GCTGTGCCGC TGCAGATCCT CATGAATGCT ATGCCAAAGT GTTCGATGAA 
TTTAAACCTC TTGTGGAAGA GCCTCAGAAT TTAATCAAAC AAAATTGTGA GCTTTTTGAG 
CAGCTTGGAG AGTACAAATT CCAGAATGCG CTATTAGTTC GTTACACCAA GAAAGTACCC 
CAAGTGTCAA CTCCAACTCT TGTAGAGGTC TCAAGAAACC TAGGAAAAGT GGGCAGCAAA 
TGTTGTAAAC ATCCTGAAGC AAAAAGAATG CCCTGTGCAG AAGACTATCT ATCCGTGGTC 
CTGAACCAGT TATGTGTGTT GCATGAGAAA ACGCCAGTAA GTGACAGAGT CACCAAATGC 
TGCACAGAAT CCTTGGTGAA CAGGCGACCA TGCTTTTCAG CTCTGGAAGT CGATGAAACA 
TACGTTCCCA AAGAGTTTAA TGCTGAAACA TTCACCTTCC ATGCAGATAT ATGCACACTT 
TCTGAGAAGG AGAGACAAAT CAAGAAACAA ACTGCACTTG TTGAGCTCGT GAAACACAAG 
CCCAAGGCAA CAAAAGAGCA ACTGAAAGCT GTTATGGATG ATTTCGCAGC TTTTGTAGAG 
AAGTGCTGCA AGGCTGACGA TAAGGAGACC TGCTTTGCCG AGGAGGGTAA AAAACTTGTT 
GCTGCAAGTC AAGCTGCCTT AGGCTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Bilirubin Albumin Binding and Unbound Unconjugated Hyperbilirubinemia in Premature Infants.
The Journal of pediatrics19247-52(2018 Jan)
Amin SB,Wang H

Physiological serum copper concentrations found in malignancies cause unfolding induced aggregation of human serum albumin in vitro.
Archives of biochemistry and biophysics63671-78(2017 Dec)
Rizvi A,Furkan M,Naseem I

Proteolytic processing of human serum albumin generates EPI-X4, an endogenous antagonist of CXCR4.
Journal of leukocyte biology99(6)863-8(2016 06)
Zirafi O,Hermann PC,M?nch J

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ALB cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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