ERCC5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ERCC5
Entrez Gene ID	2073
Full Name	ERCC excision repair 5, endonuclease
Synonyms	COFS3,ERCC5-201,ERCM2,UVDR,XPG,XPGC
General protein information	Preferred Names ERCC excision repair 5, endonuclease Names DNA repair protein complementing XP-G cells DNA excision repair protein ERCC-5 XPG-complementing protein excision repair cross-complementation group 5 excision repair cross-complementing rodent repair deficiency, complementation group 5 xeroderma pigmentosum, complementation group G
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 13 Map Location: 13q33.1
Summary	This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, cognitive disability, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene. [provided by RefSeq, Feb 2011].
Disorder MIM:	133530
Disorder Html:	Xeroderma pigmentosum, group G, 278780 (3); Xeroderma pigmentosum, group G/Cockayne syndrome, 278780 (3); Cerebrooculofacioskeletal syndrome 3, 616570 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_000123.4	NP_000114.3	DNA repair protein complementing XP-G cells
NM_000123.3	NP_000114.2	DNA repair protein complementing XP-G cells

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ERCC5	XP_003314253.1
Rattus norvegicus (Norway rat)	Ercc5	XP_006244951.1
Homo sapiens (human)	ERCC5	NP_000114.2
Mus musculus (house mouse)	Ercc5	NP_035859.2
Bos taurus (cattle)	ERCC5	NP_001030353.1
Canis lupus familiaris (dog)	ERCC5	XP_003639860.1
	ERCC5	XP_001096257.2
Gallus gallus (chicken)	ERCC5	NP_001029995.1

Gene Ontology

The following ERCC5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ERCC5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu20331	NM_000123.3 Latest version!	Homo sapiens ERCC excision repair 5, endonuclease (ERCC5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu109351	NM_000123.4 Latest version!	Homo sapiens ERCC excision repair 5, endonuclease (ERCC5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ERCC5 ( NM_000123.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000114.2 Homo sapiens ERCC excision repair 5, endonuclease (ERCC5), mRNA.

Price & Availability↑

CloneID	OHu20331
Clone ID Related Accession (Same CDS sequence)	NM_000123.3
Accession Version	NM_000123.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3561bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-06
Organism	Homo sapiens(human)
Product	DNA repair protein complementing XP-G cells
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA195001.1, X69978.1, BQ002437.1 and BE223050.1. This sequence is a reference standard in the RefSeqGene project. On Mar 1, 2011 this sequence version replaced NM_000123.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.204208.1, SRR1803617.104194.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGGTCC AGGGGCTCTG GAAGCTGCTG GAGTGCTCCG GGCGGCAGGT CAGCCCCGAA 
GCGCTGGAAG GGAAGATCCT GGCTGTTGAT ATTAGCATTT GGTTAAACCA AGCACTTAAA 
GGAGTCCGGG ATCGCCATGG GAACTCAATA GAAAATCCTC ATCTTCTCAC TTTGTTTCAT 
CGGCTCTGCA AACTCTTATT TTTTCGAATT CGTCCTATTT TTGTGTTTGA TGGGGATGCT 
CCACTATTGA AGAAACAGAC TTTGGTGAAG AGAAGGCAGA GAAAGGACTT AGCGTCCAGT 
GACTCCAGGA AAACGACAGA GAAGCTTCTG AAAACATTTT TGAAAAGACA AGCCATCAAA 
ACTGCCTTCA GAAGCAAAAG AGATGAAGCA CTACCCAGTC TTACCCAAGT TCGAAGAGAA 
AACGACCTCT ATGTTTTGCC TCCTTTACAA GAGGAAGAAA AACACAGTTC AGAAGAGGAA 
GATGAAAAAG AATGGCAAGA AAGAATGAAT CAAAAACAAG CATTACAGGA AGAGTTCTTT 
CATAATCCTC AAGCGATAGA TATTGAGTCT GAGGACTTCA GCAGCCTGCC CCCTGAAGTA 
AAGCATGAAA TCTTGACTGA TATGAAAGAG TTCACCAAGC GCAGAAGAAC ATTATTTGAA 
GCAATGCCAG AGGAGTCTGA TGACTTTTCA CAGTACCAAC TCAAAGGCTT GCTTAAAAAG 
AACTATCTGA ACCAGCATAT AGAACATGTC CAAAAGGAAA TGAATCAGCA ACATTCAGGA 
CACATCCGAA GGCAGTATGA AGATGAAGGG GGCTTTCTGA AGGAGGTAGA GTCAAGGAGA 
GTGGTCTCTG AAGACACTTC ACATTACATC TTGATAAAAG GTATTCAAGC TAAGACAGTT 
GCAGAAGTGG ATTCAGAGTC TCTTCCTTCT TCCAGCAAAA TGCACGGCAT GTCTTTTGAC 
GTGAAGTCAT CTCCATGTGA AAAACTGAAG ACAGAGAAAG AGCCTGATGC TACCCCTCCT 
TCTCCAAGAA CTTTACTAGC TATGCAAGCT GCCCTGCTGG GAAGTAGCTC AGAAGAGGAG 
CTGGAGAGTG AAAATCGAAG GCAGGCCCGT GGGAGGAACG CACCTGCTGC TGTAGACGAA 
GGCTCCATAT CACCCCGGAC TCTTTCAGCC ATTAAGAGAG CTCTTGACGA TGACGAAGAT 
GTAAAAGTGT GTGCTGGGGA TGATGTGCAG ACGGGAGGGC CAGGAGCAGA AGAAATGCGT 
ATAAACAGCT CCACCGAGAA CAGTGATGAA GGACTTAAAG TGAGAGATGG AAAAGGAATA 
CCGTTTACTG CAACACTTGC GTCATCTAGT GTGAACTCTG CAGAGGAGCA CGTAGCCAGC 
ACTAATGAGG GGAGAGAGCC CACAGACTCA GTTCCAAAAG AACAAATGTC ACTTGTTCAC 
GTGGGGACTG AAGCCTTTCC GATAAGTGAT GAGTCTATGA TTAAGGACAG AAAAGATCGG 
CTGCCTCTGG AGAGTGCAGT GGTTAGACAT AGTGACGCAC CTGGGCTCCC GAATGGAAGG 
GAACTGACAC CGGCATCTCC AACTTGTACA AATTCTGTGT CAAAGAATGA AACACATGCT 
GAAGTGCTTG AGCAGCAGAA CGAACTTTGC CCATATGAGA GTAAATTCGA TTCTTCTCTT 
CTTTCAAGTG ATGATGAAAC AAAATGTAAA CCGAATTCTG CTTCTGAAGT CATTGGCCCT 
GTCAGTTTGC AAGAAACAAG TAGCATAGTA AGTGTCCCTT CAGAGGCAGT AGATAATGTG 
GAAAATGTGG TGTCATTTAA TGCTAAAGAG CATGAGAATT TTCTGGAAAC CATCCAAGAA 
CAGCAGACCA CTGAATCTGC AGGCCAGGAT TTAATTTCCA TTCCAAAGGC CGTGGAACCA 
ATGGAAATTG ACTCGGAAGA AAGTGAATCT GATGGAAGTT TCATTGAAGT GCAAAGTGTG 
ATTAGTGATG AGGAACTTCA AGCAGAATTC CCTGAAACTT CCAAACCTCC CTCAGAACAA 
GGCGAAGAGG AACTGGTAGG AACTAGGGAG GGAGAAGCCC CTGCTGAGTC CGAGAGCCTC 
CTGAGGGACA ACTCTGAGAG GGACGACGTG GATGGTGAGC CACAGGAAGC TGAGAAAGAT 
GCGGAAGATT CGCTCCATGA ATGGCAAGAT ATTAATTTGG AGGAGTTGGA AACTCTGGAG 
AGCAACCTCT TAGCACAGCA GAATTCACTG AAAGCTCAAA AACAGCAGCA AGAACGGATC 
GCTGCTACTG TCACCGGACA GATGTTCCTG GAAAGCCAGG AACTCCTGCG CCTGTTCGGC 
ATTCCCTACA TCCAGGCTCC CATGGAAGCA GAGGCGCAGT GCGCCATCCT GGACCTGACT 
GATCAGACTT CCGGAACCAT CACTGATGAC AGTGATATCT GGCTGTTTGG AGCGCGGCAT 
GTCTATAGAA ACTTTTTTAA TAAAAACAAG TTTGTAGAAT ATTATCAATA TGTGGACTTT 
CACAATCAAT TGGGATTGGA CCGGAATAAG TTAATAAATT TGGCTTATTT GCTTGGAAGT 
GATTATACCG AAGGAATACC AACTGTGGGT TGTGTAACCG CCATGGAAAT TCTCAATGAA 
TTCCCTGGGC ATGGCCTGGA ACCTCTCCTA AAATTCTCAG AATGGTGGCA TGAAGCTCAA 
AAAAATCCAA AGATAAGACC TAATCCTCAT GACACCAAAG TGAAAAAAAA ATTACGGACA 
TTGCAACTCA CCCCTGGCTT TCCTAACCCA GCTGTTGCCG AGGCCTACCT CAAACCCGTG 
GTGGATGACT CGAAGGGATC CTTTCTGTGG GGGAAACCTG ATCTCGACAA AATTAGAGAA 
TTTTGTCAGC GGTATTTCGG CTGGAACAGA ACGAAGACAG ATGAATCTCT GTTTCCTGTA 
TTAAAGCAAC TCGATGCCCA GCAGACACAG CTCCGAATTG ATTCCTTCTT TAGATTAGCA 
CAACAGGAGA AAGAAGATGC TAAACGTATT AAGAGCCAGA GACTAAACAG AGCTGTGACA 
TGTATGCTAA GGAAAGAGAA AGAAGCAGCA GCCAGCGAAA TAGAAGCAGT TTCTGTTGCC 
ATGGAGAAAG AATTTGAGCT ACTTGATAAG GCAAAACGAA AAACCCAGAA GAGAGGCATA 
ACAAATACCT TAGAAGAGTC ATCAAGCCTG AAAAGAAAGA GGCTTTCAGA TTCTAAACGA 
AAGAATACAT GCGGTGGATT TTTGGGGGAG ACCTGCCTCT CAGAATCATC TGATGGATCT 
TCAAGTGAAG ATGCTGAAAG TTCATCTTTA ATGAATGTAC AAAGGAGAAC AGCTGCGAAA 
GAGCCAAAAA CCAGTGCTTC AGATTCGCAG AACTCAGTGA AGGAAGCTCC CGTGAAGAAT 
GGAGGTGCGA CCACCAGCAG CTCTAGTGAT AGTGATGACG ATGGAGGGAA AGAGAAGATG 
GTCCTCGTGA CCGCCAGATC TGTGTTTGGG AAGAAAAGAA GGAAACTAAG ACGTGCGAGG 
GGAAGAAAAA GGAAAACCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000114.2
CDS	427..3987
Translation	MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEALPSLTQVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLEPLLKFSEWWHEAQKNPKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLAQQEKEDAKRIKSQRLNRAVTCMLRKEKEAAASEIEAVSVAMEKEFELLDKAKRKTQKRGITNTLEESSSLKRKRLSDSKRKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKEKMVLVTARSVFGKKRRKLRRARGRKRKT

Target ORF information:

RefSeq Version	NM_000123.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ERCC excision repair 5, endonuclease (ERCC5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000123.3

ORF Insert Sequence:

ATGGGGGTCC AGGGGCTCTG GAAGCTGCTG GAGTGCTCCG GGCGGCAGGT CAGCCCCGAA 
GCGCTGGAAG GGAAGATCCT GGCTGTTGAT ATTAGCATTT GGTTAAACCA AGCACTTAAA 
GGAGTCCGGG ATCGCCATGG GAACTCAATA GAAAATCCTC ATCTTCTCAC TTTGTTTCAT 
CGGCTCTGCA AACTCTTATT TTTTCGAATT CGTCCTATTT TTGTGTTTGA TGGGGATGCT 
CCACTATTGA AGAAACAGAC TTTGGTGAAG AGAAGGCAGA GAAAGGACTT AGCGTCCAGT 
GACTCCAGGA AAACGACAGA GAAGCTTCTG AAAACATTTT TGAAAAGACA AGCCATCAAA 
ACTGCCTTCA GAAGCAAAAG AGATGAAGCA CTACCCAGTC TTACCCAAGT TCGAAGAGAA 
AACGACCTCT ATGTTTTGCC TCCTTTACAA GAGGAAGAAA AACACAGTTC AGAAGAGGAA 
GATGAAAAAG AATGGCAAGA AAGAATGAAT CAAAAACAAG CATTACAGGA AGAGTTCTTT 
CATAATCCTC AAGCGATAGA TATTGAGTCT GAGGACTTCA GCAGCCTGCC CCCTGAAGTA 
AAGCATGAAA TCTTGACTGA TATGAAAGAG TTCACCAAGC GCAGAAGAAC ATTATTTGAA 
GCAATGCCAG AGGAGTCTGA TGACTTTTCA CAGTACCAAC TCAAAGGCTT GCTTAAAAAG 
AACTATCTGA ACCAGCATAT AGAACATGTC CAAAAGGAAA TGAATCAGCA ACATTCAGGA 
CACATCCGAA GGCAGTATGA AGATGAAGGG GGCTTTCTGA AGGAGGTAGA GTCAAGGAGA 
GTGGTCTCTG AAGACACTTC ACATTACATC TTGATAAAAG GTATTCAAGC TAAGACAGTT 
GCAGAAGTGG ATTCAGAGTC TCTTCCTTCT TCCAGCAAAA TGCACGGCAT GTCTTTTGAC 
GTGAAGTCAT CTCCATGTGA AAAACTGAAG ACAGAGAAAG AGCCTGATGC TACCCCTCCT 
TCTCCAAGAA CTTTACTAGC TATGCAAGCT GCCCTGCTGG GAAGTAGCTC AGAAGAGGAG 
CTGGAGAGTG AAAATCGAAG GCAGGCCCGT GGGAGGAACG CACCTGCTGC TGTAGACGAA 
GGCTCCATAT CACCCCGGAC TCTTTCAGCC ATTAAGAGAG CTCTTGACGA TGACGAAGAT 
GTAAAAGTGT GTGCTGGGGA TGATGTGCAG ACGGGAGGGC CAGGAGCAGA AGAAATGCGT 
ATAAACAGCT CCACCGAGAA CAGTGATGAA GGACTTAAAG TGAGAGATGG AAAAGGAATA 
CCGTTTACTG CAACACTTGC GTCATCTAGT GTGAACTCTG CAGAGGAGCA CGTAGCCAGC 
ACTAATGAGG GGAGAGAGCC CACAGACTCA GTTCCAAAAG AACAAATGTC ACTTGTTCAC 
GTGGGGACTG AAGCCTTTCC GATAAGTGAT GAGTCTATGA TTAAGGACAG AAAAGATCGG 
CTGCCTCTGG AGAGTGCAGT GGTTAGACAT AGTGACGCAC CTGGGCTCCC GAATGGAAGG 
GAACTGACAC CGGCATCTCC AACTTGTACA AATTCTGTGT CAAAGAATGA AACACATGCT 
GAAGTGCTTG AGCAGCAGAA CGAACTTTGC CCATATGAGA GTAAATTCGA TTCTTCTCTT 
CTTTCAAGTG ATGATGAAAC AAAATGTAAA CCGAATTCTG CTTCTGAAGT CATTGGCCCT 
GTCAGTTTGC AAGAAACAAG TAGCATAGTA AGTGTCCCTT CAGAGGCAGT AGATAATGTG 
GAAAATGTGG TGTCATTTAA TGCTAAAGAG CATGAGAATT TTCTGGAAAC CATCCAAGAA 
CAGCAGACCA CTGAATCTGC AGGCCAGGAT TTAATTTCCA TTCCAAAGGC CGTGGAACCA 
ATGGAAATTG ACTCGGAAGA AAGTGAATCT GATGGAAGTT TCATTGAAGT GCAAAGTGTG 
ATTAGTGATG AGGAACTTCA AGCAGAATTC CCTGAAACTT CCAAACCTCC CTCAGAACAA 
GGCGAAGAGG AACTGGTAGG AACTAGGGAG GGAGAAGCCC CTGCTGAGTC CGAGAGCCTC 
CTGAGGGACA ACTCTGAGAG GGACGACGTG GATGGTGAGC CACAGGAAGC TGAGAAAGAT 
GCGGAAGATT CGCTCCATGA ATGGCAAGAT ATTAATTTGG AGGAGTTGGA AACTCTGGAG 
AGCAACCTCT TAGCACAGCA GAATTCACTG AAAGCTCAAA AACAGCAGCA AGAACGGATC 
GCTGCTACTG TCACCGGACA GATGTTCCTG GAAAGCCAGG AACTCCTGCG CCTGTTCGGC 
ATTCCCTACA TCCAGGCTCC CATGGAAGCA GAGGCGCAGT GCGCCATCCT GGACCTGACT 
GATCAGACTT CCGGAACCAT CACTGATGAC AGTGATATCT GGCTGTTTGG AGCGCGGCAT 
GTCTATAGAA ACTTTTTTAA TAAAAACAAG TTTGTAGAAT ATTATCAATA TGTGGACTTT 
CACAATCAAT TGGGATTGGA CCGGAATAAG TTAATAAATT TGGCTTATTT GCTTGGAAGT 
GATTATACCG AAGGAATACC AACTGTGGGT TGTGTAACCG CCATGGAAAT TCTCAATGAA 
TTCCCTGGGC ATGGCCTGGA ACCTCTCCTA AAATTCTCAG AATGGTGGCA TGAAGCTCAA 
AAAAATCCAA AGATAAGACC TAATCCTCAT GACACCAAAG TGAAAAAAAA ATTACGGACA 
TTGCAACTCA CCCCTGGCTT TCCTAACCCA GCTGTTGCCG AGGCCTACCT CAAACCCGTG 
GTGGATGACT CGAAGGGATC CTTTCTGTGG GGGAAACCTG ATCTCGACAA AATTAGAGAA 
TTTTGTCAGC GGTATTTCGG CTGGAACAGA ACGAAGACAG ATGAATCTCT GTTTCCTGTA 
TTAAAGCAAC TCGATGCCCA GCAGACACAG CTCCGAATTG ATTCCTTCTT TAGATTAGCA 
CAACAGGAGA AAGAAGATGC TAAACGTATT AAGAGCCAGA GACTAAACAG AGCTGTGACA 
TGTATGCTAA GGAAAGAGAA AGAAGCAGCA GCCAGCGAAA TAGAAGCAGT TTCTGTTGCC 
ATGGAGAAAG AATTTGAGCT ACTTGATAAG GCAAAACGAA AAACCCAGAA GAGAGGCATA 
ACAAATACCT TAGAAGAGTC ATCAAGCCTG AAAAGAAAGA GGCTTTCAGA TTCTAAACGA 
AAGAATACAT GCGGTGGATT TTTGGGGGAG ACCTGCCTCT CAGAATCATC TGATGGATCT 
TCAAGTGAAG ATGCTGAAAG TTCATCTTTA ATGAATGTAC AAAGGAGAAC AGCTGCGAAA 
GAGCCAAAAA CCAGTGCTTC AGATTCGCAG AACTCAGTGA AGGAAGCTCC CGTGAAGAAT 
GGAGGTGCGA CCACCAGCAG CTCTAGTGAT AGTGATGACG ATGGAGGGAA AGAGAAGATG 
GTCCTCGTGA CCGCCAGATC TGTGTTTGGG AAGAAAAGAA GGAAACTAAG ACGTGCGAGG 
GGAAGAAAAA GGAAAACCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ERCC5 ( NM_000123.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000114.3 Homo sapiens ERCC excision repair 5, endonuclease (ERCC5), mRNA.

Price & Availability↑

CloneID	OHu109351
Clone ID Related Accession (Same CDS sequence)	NM_000123.4
Accession Version	NM_000123.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3561bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	DNA repair protein complementing XP-G cells
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL157769.12. On Dec 4, 2019 this sequence version replaced NM_000123.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF462447.1, X69978.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGGTCC AGGGGCTCTG GAAGCTGCTG GAGTGCTCCG GGCGGCAGGT CAGCCCCGAA 
GCGCTGGAAG GGAAGATCCT GGCTGTTGAT ATTAGCATTT GGTTAAACCA AGCACTTAAA 
GGAGTCCGGG ATCGCCATGG GAACTCAATA GAAAATCCTC ATCTTCTCAC TTTGTTTCAT 
CGGCTCTGCA AACTCTTATT TTTTCGAATT CGTCCTATTT TTGTGTTTGA TGGGGATGCT 
CCACTATTGA AGAAACAGAC TTTGGTGAAG AGAAGGCAGA GAAAGGACTT AGCGTCCAGT 
GACTCCAGGA AAACGACAGA GAAGCTTCTG AAAACATTTT TGAAAAGACA AGCCATCAAA 
ACTGCCTTCA GAAGCAAAAG AGATGAAGCA CTACCCAGTC TTACCCAAGT TCGAAGAGAA 
AACGACCTCT ATGTTTTGCC TCCTTTACAA GAGGAAGAAA AACACAGTTC AGAAGAGGAA 
GATGAAAAAG AATGGCAAGA AAGAATGAAT CAAAAACAAG CATTACAGGA AGAGTTCTTT 
CATAATCCTC AAGCGATAGA TATTGAGTCT GAGGACTTCA GCAGCCTGCC CCCTGAAGTA 
AAGCATGAAA TCTTGACTGA TATGAAAGAG TTCACCAAGC GCAGAAGAAC ATTATTTGAA 
GCAATGCCAG AGGAGTCTGA TGACTTTTCA CAGTACCAAC TCAAAGGCTT GCTTAAAAAG 
AACTATCTGA ACCAGCATAT AGAACATGTC CAAAAGGAAA TGAATCAGCA ACATTCAGGA 
CACATCCGAA GGCAGTATGA AGATGAAGGG GGCTTTCTGA AGGAGGTAGA GTCAAGGAGA 
GTGGTCTCTG AAGACACTTC ACATTACATC TTGATAAAAG GTATTCAAGC TAAGACAGTT 
GCAGAAGTGG ATTCAGAGTC TCTTCCTTCT TCCAGCAAAA TGCACGGCAT GTCTTTTGAC 
GTGAAGTCAT CTCCATGTGA AAAACTGAAG ACAGAGAAAG AGCCTGATGC TACCCCTCCT 
TCTCCAAGAA CTTTACTAGC TATGCAAGCT GCCCTGCTGG GAAGTAGCTC AGAAGAGGAG 
CTGGAGAGTG AAAATCGAAG GCAGGCCCGT GGGAGGAACG CACCTGCTGC TGTAGACGAA 
GGCTCCATAT CACCCCGGAC TCTTTCAGCC ATTAAGAGAG CTCTTGACGA TGACGAAGAT 
GTAAAAGTGT GTGCTGGGGA TGATGTGCAG ACGGGAGGGC CAGGAGCAGA AGAAATGCGT 
ATAAACAGCT CCACCGAGAA CAGTGATGAA GGACTTAAAG TGAGAGATGG AAAAGGAATA 
CCGTTTACTG CAACACTTGC GTCATCTAGT GTGAACTCTG CAGAGGAGCA CGTAGCCAGC 
ACTAATGAGG GGAGAGAGCC CACAGACTCA GTTCCAAAAG AACAAATGTC ACTTGTTCAC 
GTGGGGACTG AAGCCTTTCC GATAAGTGAT GAGTCTATGA TTAAGGACAG AAAAGATCGG 
CTGCCTCTGG AGAGTGCAGT GGTTAGACAT AGTGACGCAC CTGGGCTCCC GAATGGAAGG 
GAACTGACAC CGGCATCTCC AACTTGTACA AATTCTGTGT CAAAGAATGA AACACATGCT 
GAAGTGCTTG AGCAGCAGAA CGAACTTTGC CCATATGAGA GTAAATTCGA TTCTTCTCTT 
CTTTCAAGTG ATGATGAAAC AAAATGTAAA CCGAATTCTG CTTCTGAAGT CATTGGCCCT 
GTCAGTTTGC AAGAAACAAG TAGCATAGTA AGTGTCCCTT CAGAGGCAGT AGATAATGTG 
GAAAATGTGG TGTCATTTAA TGCTAAAGAG CATGAGAATT TTCTGGAAAC CATCCAAGAA 
CAGCAGACCA CTGAATCTGC AGGCCAGGAT TTAATTTCCA TTCCAAAGGC CGTGGAACCA 
ATGGAAATTG ACTCGGAAGA AAGTGAATCT GATGGAAGTT TCATTGAAGT GCAAAGTGTG 
ATTAGTGATG AGGAACTTCA AGCAGAATTC CCTGAAACTT CCAAACCTCC CTCAGAACAA 
GGCGAAGAGG AACTGGTAGG AACTAGGGAG GGAGAAGCCC CTGCTGAGTC CGAGAGCCTC 
CTGAGGGACA ACTCTGAGAG GGACGACGTG GATGGTGAGC CACAGGAAGC TGAGAAAGAT 
GCGGAAGATT CGCTCCATGA ATGGCAAGAT ATTAATTTGG AGGAGTTGGA AACTCTGGAG 
AGCAACCTCT TAGCACAGCA GAATTCACTG AAAGCTCAAA AACAGCAGCA AGAACGGATC 
GCTGCTACTG TCACCGGACA GATGTTCCTG GAAAGCCAGG AACTCCTGCG CCTGTTCGGC 
ATTCCCTACA TCCAGGCTCC CATGGAAGCA GAGGCGCAGT GCGCCATCCT GGACCTGACT 
GATCAGACTT CCGGAACCAT CACTGATGAC AGTGATATCT GGCTGTTTGG AGCGCGGCAT 
GTCTATAGAA ACTTTTTTAA TAAAAACAAG TTTGTAGAAT ATTATCAATA TGTGGACTTT 
CACAATCAAT TGGGATTGGA CCGGAATAAG TTAATAAATT TGGCTTATTT GCTTGGAAGT 
GATTATACCG AAGGAATACC AACTGTGGGT TGTGTAACCG CCATGGAAAT TCTCAATGAA 
TTCCCTGGGC ATGGCCTGGA ACCTCTCCTA AAATTCTCAG AATGGTGGCA TGAAGCTCAA 
AAAAATCCAA AGATAAGACC TAATCCTCAT GACACCAAAG TGAAAAAAAA ATTACGGACA 
TTGCAACTCA CCCCTGGCTT TCCTAACCCA GCTGTTGCCG AGGCCTACCT CAAACCCGTG 
GTGGATGACT CGAAGGGATC CTTTCTGTGG GGGAAACCTG ATCTCGACAA AATTAGAGAA 
TTTTGTCAGC GGTATTTCGG CTGGAACAGA ACGAAGACAG ATGAATCTCT GTTTCCTGTA 
TTAAAGCAAC TCGATGCCCA GCAGACACAG CTCCGAATTG ATTCCTTCTT TAGATTAGCA 
CAACAGGAGA AAGAAGATGC TAAACGTATT AAGAGCCAGA GACTAAACAG AGCTGTGACA 
TGTATGCTAA GGAAAGAGAA AGAAGCAGCA GCCAGCGAAA TAGAAGCAGT TTCTGTTGCC 
ATGGAGAAAG AATTTGAGCT ACTTGATAAG GCAAAAGGAA AAACCCAGAA GAGAGGCATA 
ACAAATACCT TAGAAGAGTC ATCAAGCCTG AAAAGAAAGA GGCTTTCAGA TTCTAAAGGA 
AAGAATACAT GCGGTGGATT TTTGGGGGAG ACCTGCCTCT CAGAATCATC TGATGGATCT 
TCAAGTGAAG ATGCTGAAAG TTCATCTTTA ATGAATGTAC AAAGGAGAAC AGCTGCGAAA 
GAGCCAAAAA CCAGTGCTTC AGATTCGCAG AACTCAGTGA AGGAAGCTCC CGTGAAGAAT 
GGAGGTGCGA CCACCAGCAG CTCTAGTGAT AGTGATGACG ATGGAGGGAA AGAGAAGATG 
GTCCTCGTGA CCGCCAGATC TGTGTTTGGG AAGAAAAGAA GGAAACTAAG ACGTGCGAGG 
GGAAGAAAAA GGAAAACCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000114.3
CDS	236..3796
Translation	MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEALPSLTQVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLEPLLKFSEWWHEAQKNPKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLAQQEKEDAKRIKSQRLNRAVTCMLRKEKEAAASEIEAVSVAMEKEFELLDKAKGKTQKRGITNTLEESSSLKRKRLSDSKGKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKEKMVLVTARSVFGKKRRKLRRARGRKRKT

Target ORF information:

RefSeq Version	NM_000123.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ERCC excision repair 5, endonuclease (ERCC5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000123.4

ORF Insert Sequence:

ATGGGGGTCC AGGGGCTCTG GAAGCTGCTG GAGTGCTCCG GGCGGCAGGT CAGCCCCGAA 
GCGCTGGAAG GGAAGATCCT GGCTGTTGAT ATTAGCATTT GGTTAAACCA AGCACTTAAA 
GGAGTCCGGG ATCGCCATGG GAACTCAATA GAAAATCCTC ATCTTCTCAC TTTGTTTCAT 
CGGCTCTGCA AACTCTTATT TTTTCGAATT CGTCCTATTT TTGTGTTTGA TGGGGATGCT 
CCACTATTGA AGAAACAGAC TTTGGTGAAG AGAAGGCAGA GAAAGGACTT AGCGTCCAGT 
GACTCCAGGA AAACGACAGA GAAGCTTCTG AAAACATTTT TGAAAAGACA AGCCATCAAA 
ACTGCCTTCA GAAGCAAAAG AGATGAAGCA CTACCCAGTC TTACCCAAGT TCGAAGAGAA 
AACGACCTCT ATGTTTTGCC TCCTTTACAA GAGGAAGAAA AACACAGTTC AGAAGAGGAA 
GATGAAAAAG AATGGCAAGA AAGAATGAAT CAAAAACAAG CATTACAGGA AGAGTTCTTT 
CATAATCCTC AAGCGATAGA TATTGAGTCT GAGGACTTCA GCAGCCTGCC CCCTGAAGTA 
AAGCATGAAA TCTTGACTGA TATGAAAGAG TTCACCAAGC GCAGAAGAAC ATTATTTGAA 
GCAATGCCAG AGGAGTCTGA TGACTTTTCA CAGTACCAAC TCAAAGGCTT GCTTAAAAAG 
AACTATCTGA ACCAGCATAT AGAACATGTC CAAAAGGAAA TGAATCAGCA ACATTCAGGA 
CACATCCGAA GGCAGTATGA AGATGAAGGG GGCTTTCTGA AGGAGGTAGA GTCAAGGAGA 
GTGGTCTCTG AAGACACTTC ACATTACATC TTGATAAAAG GTATTCAAGC TAAGACAGTT 
GCAGAAGTGG ATTCAGAGTC TCTTCCTTCT TCCAGCAAAA TGCACGGCAT GTCTTTTGAC 
GTGAAGTCAT CTCCATGTGA AAAACTGAAG ACAGAGAAAG AGCCTGATGC TACCCCTCCT 
TCTCCAAGAA CTTTACTAGC TATGCAAGCT GCCCTGCTGG GAAGTAGCTC AGAAGAGGAG 
CTGGAGAGTG AAAATCGAAG GCAGGCCCGT GGGAGGAACG CACCTGCTGC TGTAGACGAA 
GGCTCCATAT CACCCCGGAC TCTTTCAGCC ATTAAGAGAG CTCTTGACGA TGACGAAGAT 
GTAAAAGTGT GTGCTGGGGA TGATGTGCAG ACGGGAGGGC CAGGAGCAGA AGAAATGCGT 
ATAAACAGCT CCACCGAGAA CAGTGATGAA GGACTTAAAG TGAGAGATGG AAAAGGAATA 
CCGTTTACTG CAACACTTGC GTCATCTAGT GTGAACTCTG CAGAGGAGCA CGTAGCCAGC 
ACTAATGAGG GGAGAGAGCC CACAGACTCA GTTCCAAAAG AACAAATGTC ACTTGTTCAC 
GTGGGGACTG AAGCCTTTCC GATAAGTGAT GAGTCTATGA TTAAGGACAG AAAAGATCGG 
CTGCCTCTGG AGAGTGCAGT GGTTAGACAT AGTGACGCAC CTGGGCTCCC GAATGGAAGG 
GAACTGACAC CGGCATCTCC AACTTGTACA AATTCTGTGT CAAAGAATGA AACACATGCT 
GAAGTGCTTG AGCAGCAGAA CGAACTTTGC CCATATGAGA GTAAATTCGA TTCTTCTCTT 
CTTTCAAGTG ATGATGAAAC AAAATGTAAA CCGAATTCTG CTTCTGAAGT CATTGGCCCT 
GTCAGTTTGC AAGAAACAAG TAGCATAGTA AGTGTCCCTT CAGAGGCAGT AGATAATGTG 
GAAAATGTGG TGTCATTTAA TGCTAAAGAG CATGAGAATT TTCTGGAAAC CATCCAAGAA 
CAGCAGACCA CTGAATCTGC AGGCCAGGAT TTAATTTCCA TTCCAAAGGC CGTGGAACCA 
ATGGAAATTG ACTCGGAAGA AAGTGAATCT GATGGAAGTT TCATTGAAGT GCAAAGTGTG 
ATTAGTGATG AGGAACTTCA AGCAGAATTC CCTGAAACTT CCAAACCTCC CTCAGAACAA 
GGCGAAGAGG AACTGGTAGG AACTAGGGAG GGAGAAGCCC CTGCTGAGTC CGAGAGCCTC 
CTGAGGGACA ACTCTGAGAG GGACGACGTG GATGGTGAGC CACAGGAAGC TGAGAAAGAT 
GCGGAAGATT CGCTCCATGA ATGGCAAGAT ATTAATTTGG AGGAGTTGGA AACTCTGGAG 
AGCAACCTCT TAGCACAGCA GAATTCACTG AAAGCTCAAA AACAGCAGCA AGAACGGATC 
GCTGCTACTG TCACCGGACA GATGTTCCTG GAAAGCCAGG AACTCCTGCG CCTGTTCGGC 
ATTCCCTACA TCCAGGCTCC CATGGAAGCA GAGGCGCAGT GCGCCATCCT GGACCTGACT 
GATCAGACTT CCGGAACCAT CACTGATGAC AGTGATATCT GGCTGTTTGG AGCGCGGCAT 
GTCTATAGAA ACTTTTTTAA TAAAAACAAG TTTGTAGAAT ATTATCAATA TGTGGACTTT 
CACAATCAAT TGGGATTGGA CCGGAATAAG TTAATAAATT TGGCTTATTT GCTTGGAAGT 
GATTATACCG AAGGAATACC AACTGTGGGT TGTGTAACCG CCATGGAAAT TCTCAATGAA 
TTCCCTGGGC ATGGCCTGGA ACCTCTCCTA AAATTCTCAG AATGGTGGCA TGAAGCTCAA 
AAAAATCCAA AGATAAGACC TAATCCTCAT GACACCAAAG TGAAAAAAAA ATTACGGACA 
TTGCAACTCA CCCCTGGCTT TCCTAACCCA GCTGTTGCCG AGGCCTACCT CAAACCCGTG 
GTGGATGACT CGAAGGGATC CTTTCTGTGG GGGAAACCTG ATCTCGACAA AATTAGAGAA 
TTTTGTCAGC GGTATTTCGG CTGGAACAGA ACGAAGACAG ATGAATCTCT GTTTCCTGTA 
TTAAAGCAAC TCGATGCCCA GCAGACACAG CTCCGAATTG ATTCCTTCTT TAGATTAGCA 
CAACAGGAGA AAGAAGATGC TAAACGTATT AAGAGCCAGA GACTAAACAG AGCTGTGACA 
TGTATGCTAA GGAAAGAGAA AGAAGCAGCA GCCAGCGAAA TAGAAGCAGT TTCTGTTGCC 
ATGGAGAAAG AATTTGAGCT ACTTGATAAG GCAAAAGGAA AAACCCAGAA GAGAGGCATA 
ACAAATACCT TAGAAGAGTC ATCAAGCCTG AAAAGAAAGA GGCTTTCAGA TTCTAAAGGA 
AAGAATACAT GCGGTGGATT TTTGGGGGAG ACCTGCCTCT CAGAATCATC TGATGGATCT 
TCAAGTGAAG ATGCTGAAAG TTCATCTTTA ATGAATGTAC AAAGGAGAAC AGCTGCGAAA 
GAGCCAAAAA CCAGTGCTTC AGATTCGCAG AACTCAGTGA AGGAAGCTCC CGTGAAGAAT 
GGAGGTGCGA CCACCAGCAG CTCTAGTGAT AGTGATGACG ATGGAGGGAA AGAGAAGATG 
GTCCTCGTGA CCGCCAGATC TGTGTTTGGG AAGAAAAGAA GGAAACTAAG ACGTGCGAGG 
GGAAGAAAAA GGAAAACCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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ERCC5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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