LGI3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LGI3
Entrez Gene ID	203190
Full Name	leucine rich repeat LGI family member 3
Synonyms	LGIL4
General protein information	Preferred Names leucine rich repeat LGI family member 3 Names leucine-rich repeat LGI family member 3 LGI1-like protein 4 leucine-rich glioma-inactivated protein 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8p21.3
Disorder MIM:	608302

mRNA and Protein(s)

mRNA	Protein	Name
NM_139278.3	NP_644807.1	leucine-rich repeat LGI family member 3 precursor
NM_139278.2	NP_644807.1	leucine-rich repeat LGI family member 3 precursor
NM_139278.4	NP_644807.1	leucine-rich repeat LGI family member 3 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Lgi3	NP_660254.1
	LGI3	XP_001106283.2
Rattus norvegicus (Norway rat)	Lgi3	NP_001100747.1
Homo sapiens (human)	LGI3	NP_644807.1
Canis lupus familiaris (dog)	LGI3	XP_543254.3
Pan troglodytes (chimpanzee)	LGI3	NP_001065284.1
Bos taurus (cattle)	LGI3	XP_005210317.1
Danio rerio (zebrafish)	lgi3	NP_001034768.1

Gene Ontology
Bibliography

Related articles in PubMed

Leucine-rich glioma inactivated 3: Integrative analyses reveal its potential prognostic role in cancer.
Kwon NS, Baek KJ, Kim DS, Yun HY
Molecular medicine reports(2017 Dec)

Leucine-rich glioma inactivated 3 is a melanogenic cytokine in human skin.
Jeong HS, Jeong YM, Kim J, Lee SH, Choi HR, Park KC, Kim BJ, Baek KJ, Kwon NS, Yun HY, Kim DS
Experimental dermatology23(8)600-2(2014 Aug)

Leucine-rich glioma inactivated 3 promotes HaCaT keratinocyte migration.
Jeong YM, Park WJ, Kim MK, Baek KJ, Kwon NS, Yun HY, Kim DS
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society21(4)634-40(2013 Jul-Aug)

Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.
Weissglas-Volkov D, Aguilar-Salinas CA, Nikkola E, Deere KA, Cruz-Bautista I, Arellano-Campos O, Mu?oz-Hernandez LL, Gomez-Munguia L, Ordo?ez-S?nchez ML, Reddy PM, Lusis AJ, Matikainen N, Taskinen MR, Riba L, Cantor RM, Sinsheimer JS, Tusie-Luna T, Pajukanta P
Journal of medical genetics50(5)298-308(2013 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Leucine-rich glioma inactivated 3 is a cytokine in human skin that promotes melanin production.
Title: Leucine-rich glioma inactivated 3 is a melanogenic cytokine in human skin.

LGI3 was mostly expressed in the granular layer of the epidermis of human skin.
Title: Leucine-rich glioma inactivated 3 promotes HaCaT keratinocyte migration.

The following LGI3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LGI3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25795	NM_139278.4 Latest version!	Homo sapiens leucine rich repeat LGI family member 3 (LGI3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$229.50-$321.30 $459.00
View Old Accession Versions >>
OHu25795	NM_139278.2	Homo sapiens leucine rich repeat LGI family member 3 (LGI3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$229.50-$321.30 $459.00
OHu25795	NM_139278.3	Homo sapiens leucine rich repeat LGI family member 3 (LGI3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$229.50-$321.30 $459.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LGI3 ( NM_139278.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_644807.1 Homo sapiens leucine rich repeat LGI family member 3 (LGI3), mRNA.

Price & Availability↑

CloneID	OHu25795
Clone ID Related Accession (Same CDS sequence)	NM_139278.3 , NM_139278.2 , NM_139278.4
Accession Version	NM_139278.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1647bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	leucine-rich repeat LGI family member 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ487961.1 and BC042542.1. On Nov 22, 2018 this sequence version replaced NM_139278.2. ##Evidence-Data-START## Transcript exon combination :: AJ487961.1, AJ487518.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGGGC TGCGGGCCAG GGGGGGCCCG GGGCCGGGGC TGCTGGCGCT CTCCGCGCTC 
GGCTTCTGCC TCATGCTGCA AGTCAGCGCT AAGAGGCCCC CCAAGACGCC CCCCTGCCCG 
CCCAGCTGCT CTTGCACCAG GGACACCGCC TTCTGCGTGG ACTCAAAGGC GGTGCCCAGG 
AACCTGCCCT CGGAGGTCAT CTCCCTGACC CTGGTGAATG CCGCCTTCTC AGAGATCCAG 
GATGGAGCGT TCTCCCACCT CCCGCTGCTG CAGTTCTTGT TACTCAACTC CAACAAGTTT 
ACACTGATTG GAGACAACGC CTTCACAGGA CTGTCGCACC TGCAGTATCT CTTCATTGAG 
AACAATGACA TCTGGGCACT ATCCAAGTTC ACCTTCCGAG GACTCAAGTC CTTGACTCAC 
CTCTCGCTGG CCAACAATAA CCTGCAGACA CTGCCCAGAG ACATCTTCCG GCCCCTGGAC 
ATCCTGAATG ACTTGGACCT GCGGGGCAAC TCACTCAACT GTGACTGCAA GGTGAAGTGG 
TTGGTGGAGT GGCTGGCACA CACCAACACC ACGGTGGCAC CCATCTACTG CGCCAGCCCG 
CCCCGCTTCC AGGAGCACAA GGTGCAGGAC CTGCCGCTGC GGGAGTTCGA TTGCATCACC 
ACAGATTTTG TGTTGTACCA GACCCTGGCC TTCCCAGCAG TGTCGGCTGA GCCCTTCCTC 
TACTCCAGTG ACCTCTATTT GGCTCTGGCC CAGCCAGGAG TCAGTGCCTG CACCATCCTG 
AAGTGGGACT ATGTTGAGCG GCAGCTTCGA GACTATGATA GAATCCCAGC CCCCTCTGCA 
GTGCACTGCA AGCCGATGGT GGTGGACAGC CAGCTGTACG TGGTCGTGGC CCAGCTGTTT 
GGCGGCTCTT ACATTTACCA CTGGGATCCC AACACCACGC GCTTCACCAG GCTGCAAGAC 
ATTGACCCGC AGCGCGTGCG CAAGCCTAAC GACCTAGAAG CCTTCCGCAT CGACGGTGAC 
TGGTACTTTG CCGTGGCTGA CAGCTCCAAG GCAGGCGCCA CCAGCCTCTA CCGCTGGCAC 
CAGAATGGCT TCTACTCCCA CCAGGCACTG CACCCCTGGC ACCGTGACAC CGACCTGGAG 
TTTGTGGACG GCGAGGGCAA GCCACGGCTG ATTGTGTCCA GCAGCTCCCA GGCACCCGTC 
ATCTATCAGT GGAGTCGCAC CCAGAAGCAG TTTGTGGCCC AGGGTGAGGT GACCCAGGTG 
CCTGATGCCC AAGCTGTGAA ACACTTTCGT GCCGGCCGCG ACAGCTACCT GTGCCTCAGC 
CGCTACATTG GCGACTCCAA GATCCTGCGC TGGGAGGGTA CCCGCTTCTC GGAGGTGCAG 
GCCCTGCCCT CCCGGGGCTC GCTGGCCCTG CAGCCCTTCC TTGTGGGTGG CCGCCGCTAC 
CTGGCACTGG GCAGTGATTT CTCCTTCACC CAGATCTACC AGTGGGATGA GGGACGACAG 
AAGTTTGTAC GGTTCCAGGA GCTGGCTGTG CAGGCTCCTC GGGCCTTCTG CTACATGCCT 
GCTGGGGACG CCCAGCTACT CCTGGCCCCC AGCTTCAAGG GACAGACGCT GGTGTATAGA 
CACATTGTGG TGGATCTCAG TGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_644807.1
CDS	265..1911
Translation	MAGLRARGGPGPGLLALSALGFCLMLQVSAKRPPKTPPCPPSCSCTRDTAFCVDSKAVPRNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILNDLDLRGNSLNCDCKVKWLVEWLAHTNTTVAPIYCASPPRFQEHKVQDLPLREFDCITTDFVLYQTLAFPAVSAEPFLYSSDLYLALAQPGVSACTILKWDYVERQLRDYDRIPAPSAVHCKPMVVDSQLYVVVAQLFGGSYIYHWDPNTTRFTRLQDIDPQRVRKPNDLEAFRIDGDWYFAVADSSKAGATSLYRWHQNGFYSHQALHPWHRDTDLEFVDGEGKPRLIVSSSSQAPVIYQWSRTQKQFVAQGEVTQVPDAQAVKHFRAGRDSYLCLSRYIGDSKILRWEGTRFSEVQALPSRGSLALQPFLVGGRRYLALGSDFSFTQIYQWDEGRQKFVRFQELAVQAPRAFCYMPAGDAQLLLAPSFKGQTLVYRHIVVDLSA

Target ORF information:

RefSeq Version	NM_139278.3
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat LGI family member 3 (LGI3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139278.3

ORF Insert Sequence:

ATGGCGGGGC TGCGGGCCAG GGGGGGCCCG GGGCCGGGGC TGCTGGCGCT CTCCGCGCTC 
GGCTTCTGCC TCATGCTGCA AGTCAGCGCT AAGAGGCCCC CCAAGACGCC CCCCTGCCCG 
CCCAGCTGCT CTTGCACCAG GGACACCGCC TTCTGCGTGG ACTCAAAGGC GGTGCCCAGG 
AACCTGCCCT CGGAGGTCAT CTCCCTGACC CTGGTGAATG CCGCCTTCTC AGAGATCCAG 
GATGGAGCGT TCTCCCACCT CCCGCTGCTG CAGTTCTTGT TACTCAACTC CAACAAGTTT 
ACACTGATTG GAGACAACGC CTTCACAGGA CTGTCGCACC TGCAGTATCT CTTCATTGAG 
AACAATGACA TCTGGGCACT ATCCAAGTTC ACCTTCCGAG GACTCAAGTC CTTGACTCAC 
CTCTCGCTGG CCAACAATAA CCTGCAGACA CTGCCCAGAG ACATCTTCCG GCCCCTGGAC 
ATCCTGAATG ACTTGGACCT GCGGGGCAAC TCACTCAACT GTGACTGCAA GGTGAAGTGG 
TTGGTGGAGT GGCTGGCACA CACCAACACC ACGGTGGCAC CCATCTACTG CGCCAGCCCG 
CCCCGCTTCC AGGAGCACAA GGTGCAGGAC CTGCCGCTGC GGGAGTTCGA TTGCATCACC 
ACAGATTTTG TGTTGTACCA GACCCTGGCC TTCCCAGCAG TGTCGGCTGA GCCCTTCCTC 
TACTCCAGTG ACCTCTATTT GGCTCTGGCC CAGCCAGGAG TCAGTGCCTG CACCATCCTG 
AAGTGGGACT ATGTTGAGCG GCAGCTTCGA GACTATGATA GAATCCCAGC CCCCTCTGCA 
GTGCACTGCA AGCCGATGGT GGTGGACAGC CAGCTGTACG TGGTCGTGGC CCAGCTGTTT 
GGCGGCTCTT ACATTTACCA CTGGGATCCC AACACCACGC GCTTCACCAG GCTGCAAGAC 
ATTGACCCGC AGCGCGTGCG CAAGCCTAAC GACCTAGAAG CCTTCCGCAT CGACGGTGAC 
TGGTACTTTG CCGTGGCTGA CAGCTCCAAG GCAGGCGCCA CCAGCCTCTA CCGCTGGCAC 
CAGAATGGCT TCTACTCCCA CCAGGCACTG CACCCCTGGC ACCGTGACAC CGACCTGGAG 
TTTGTGGACG GCGAGGGCAA GCCACGGCTG ATTGTGTCCA GCAGCTCCCA GGCACCCGTC 
ATCTATCAGT GGAGTCGCAC CCAGAAGCAG TTTGTGGCCC AGGGTGAGGT GACCCAGGTG 
CCTGATGCCC AAGCTGTGAA ACACTTTCGT GCCGGCCGCG ACAGCTACCT GTGCCTCAGC 
CGCTACATTG GCGACTCCAA GATCCTGCGC TGGGAGGGTA CCCGCTTCTC GGAGGTGCAG 
GCCCTGCCCT CCCGGGGCTC GCTGGCCCTG CAGCCCTTCC TTGTGGGTGG CCGCCGCTAC 
CTGGCACTGG GCAGTGATTT CTCCTTCACC CAGATCTACC AGTGGGATGA GGGACGACAG 
AAGTTTGTAC GGTTCCAGGA GCTGGCTGTG CAGGCTCCTC GGGCCTTCTG CTACATGCCT 
GCTGGGGACG CCCAGCTACT CCTGGCCCCC AGCTTCAAGG GACAGACGCT GGTGTATAGA 
CACATTGTGG TGGATCTCAG TGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LGI3 ( NM_139278.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_644807.1 Homo sapiens leucine rich repeat LGI family member 3 (LGI3), mRNA.

Price & Availability↑

CloneID	OHu25795
Clone ID Related Accession (Same CDS sequence)	NM_139278.3 , NM_139278.2 , NM_139278.4
Accession Version	NM_139278.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1647bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	leucine-rich repeat LGI family member 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ487961.1 and BC042542.1. On Mar 23, 2004 this sequence version replaced NM_139278.1. ##Evidence-Data-START## Transcript exon combination :: AJ487961.1, AJ487518.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END##

ATGGCGGGGC TGCGGGCCAG GGGGGGCCCG GGGCCGGGGC TGCTGGCGCT CTCCGCGCTC 
GGCTTCTGCC TCATGCTGCA AGTCAGCGCT AAGAGGCCCC CCAAGACGCC CCCCTGCCCG 
CCCAGCTGCT CTTGCACCAG GGACACCGCC TTCTGCGTGG ACTCAAAGGC GGTGCCCAGG 
AACCTGCCCT CGGAGGTCAT CTCCCTGACC CTGGTGAATG CCGCCTTCTC AGAGATCCAG 
GATGGAGCGT TCTCCCACCT CCCGCTGCTG CAGTTCTTGT TACTCAACTC CAACAAGTTT 
ACACTGATTG GAGACAACGC CTTCACAGGA CTGTCGCACC TGCAGTATCT CTTCATTGAG 
AACAATGACA TCTGGGCACT ATCCAAGTTC ACCTTCCGAG GACTCAAGTC CTTGACTCAC 
CTCTCGCTGG CCAACAATAA CCTGCAGACA CTGCCCAGAG ACATCTTCCG GCCCCTGGAC 
ATCCTGAATG ACTTGGACCT GCGGGGCAAC TCACTCAACT GTGACTGCAA GGTGAAGTGG 
TTGGTGGAGT GGCTGGCACA CACCAACACC ACGGTGGCAC CCATCTACTG CGCCAGCCCG 
CCCCGCTTCC AGGAGCACAA GGTGCAGGAC CTGCCGCTGC GGGAGTTCGA TTGCATCACC 
ACAGATTTTG TGTTGTACCA GACCCTGGCC TTCCCAGCAG TGTCGGCTGA GCCCTTCCTC 
TACTCCAGTG ACCTCTATTT GGCTCTGGCC CAGCCAGGAG TCAGTGCCTG CACCATCCTG 
AAGTGGGACT ATGTTGAGCG GCAGCTTCGA GACTATGATA GAATCCCAGC CCCCTCTGCA 
GTGCACTGCA AGCCGATGGT GGTGGACAGC CAGCTGTACG TGGTCGTGGC CCAGCTGTTT 
GGCGGCTCTT ACATTTACCA CTGGGATCCC AACACCACGC GCTTCACCAG GCTGCAAGAC 
ATTGACCCGC AGCGCGTGCG CAAGCCTAAC GACCTAGAAG CCTTCCGCAT CGACGGTGAC 
TGGTACTTTG CCGTGGCTGA CAGCTCCAAG GCAGGCGCCA CCAGCCTCTA CCGCTGGCAC 
CAGAATGGCT TCTACTCCCA CCAGGCACTG CACCCCTGGC ACCGTGACAC CGACCTGGAG 
TTTGTGGACG GCGAGGGCAA GCCACGGCTG ATTGTGTCCA GCAGCTCCCA GGCACCCGTC 
ATCTATCAGT GGAGTCGCAC CCAGAAGCAG TTTGTGGCCC AGGGTGAGGT GACCCAGGTG 
CCTGATGCCC AAGCTGTGAA ACACTTTCGT GCCGGCCGCG ACAGCTACCT GTGCCTCAGC 
CGCTACATTG GCGACTCCAA GATCCTGCGC TGGGAGGGTA CCCGCTTCTC GGAGGTGCAG 
GCCCTGCCCT CCCGGGGCTC GCTGGCCCTG CAGCCCTTCC TTGTGGGTGG CCGCCGCTAC 
CTGGCACTGG GCAGTGATTT CTCCTTCACC CAGATCTACC AGTGGGATGA GGGACGACAG 
AAGTTTGTAC GGTTCCAGGA GCTGGCTGTG CAGGCTCCTC GGGCCTTCTG CTACATGCCT 
GCTGGGGACG CCCAGCTACT CCTGGCCCCC AGCTTCAAGG GACAGACGCT GGTGTATAGA 
CACATTGTGG TGGATCTCAG TGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_644807.1
CDS	290..1936
Translation	MAGLRARGGPGPGLLALSALGFCLMLQVSAKRPPKTPPCPPSCSCTRDTAFCVDSKAVPRNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILNDLDLRGNSLNCDCKVKWLVEWLAHTNTTVAPIYCASPPRFQEHKVQDLPLREFDCITTDFVLYQTLAFPAVSAEPFLYSSDLYLALAQPGVSACTILKWDYVERQLRDYDRIPAPSAVHCKPMVVDSQLYVVVAQLFGGSYIYHWDPNTTRFTRLQDIDPQRVRKPNDLEAFRIDGDWYFAVADSSKAGATSLYRWHQNGFYSHQALHPWHRDTDLEFVDGEGKPRLIVSSSSQAPVIYQWSRTQKQFVAQGEVTQVPDAQAVKHFRAGRDSYLCLSRYIGDSKILRWEGTRFSEVQALPSRGSLALQPFLVGGRRYLALGSDFSFTQIYQWDEGRQKFVRFQELAVQAPRAFCYMPAGDAQLLLAPSFKGQTLVYRHIVVDLSA

Target ORF information:

RefSeq Version	NM_139278.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat LGI family member 3 (LGI3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139278.2

ORF Insert Sequence:

ATGGCGGGGC TGCGGGCCAG GGGGGGCCCG GGGCCGGGGC TGCTGGCGCT CTCCGCGCTC 
GGCTTCTGCC TCATGCTGCA AGTCAGCGCT AAGAGGCCCC CCAAGACGCC CCCCTGCCCG 
CCCAGCTGCT CTTGCACCAG GGACACCGCC TTCTGCGTGG ACTCAAAGGC GGTGCCCAGG 
AACCTGCCCT CGGAGGTCAT CTCCCTGACC CTGGTGAATG CCGCCTTCTC AGAGATCCAG 
GATGGAGCGT TCTCCCACCT CCCGCTGCTG CAGTTCTTGT TACTCAACTC CAACAAGTTT 
ACACTGATTG GAGACAACGC CTTCACAGGA CTGTCGCACC TGCAGTATCT CTTCATTGAG 
AACAATGACA TCTGGGCACT ATCCAAGTTC ACCTTCCGAG GACTCAAGTC CTTGACTCAC 
CTCTCGCTGG CCAACAATAA CCTGCAGACA CTGCCCAGAG ACATCTTCCG GCCCCTGGAC 
ATCCTGAATG ACTTGGACCT GCGGGGCAAC TCACTCAACT GTGACTGCAA GGTGAAGTGG 
TTGGTGGAGT GGCTGGCACA CACCAACACC ACGGTGGCAC CCATCTACTG CGCCAGCCCG 
CCCCGCTTCC AGGAGCACAA GGTGCAGGAC CTGCCGCTGC GGGAGTTCGA TTGCATCACC 
ACAGATTTTG TGTTGTACCA GACCCTGGCC TTCCCAGCAG TGTCGGCTGA GCCCTTCCTC 
TACTCCAGTG ACCTCTATTT GGCTCTGGCC CAGCCAGGAG TCAGTGCCTG CACCATCCTG 
AAGTGGGACT ATGTTGAGCG GCAGCTTCGA GACTATGATA GAATCCCAGC CCCCTCTGCA 
GTGCACTGCA AGCCGATGGT GGTGGACAGC CAGCTGTACG TGGTCGTGGC CCAGCTGTTT 
GGCGGCTCTT ACATTTACCA CTGGGATCCC AACACCACGC GCTTCACCAG GCTGCAAGAC 
ATTGACCCGC AGCGCGTGCG CAAGCCTAAC GACCTAGAAG CCTTCCGCAT CGACGGTGAC 
TGGTACTTTG CCGTGGCTGA CAGCTCCAAG GCAGGCGCCA CCAGCCTCTA CCGCTGGCAC 
CAGAATGGCT TCTACTCCCA CCAGGCACTG CACCCCTGGC ACCGTGACAC CGACCTGGAG 
TTTGTGGACG GCGAGGGCAA GCCACGGCTG ATTGTGTCCA GCAGCTCCCA GGCACCCGTC 
ATCTATCAGT GGAGTCGCAC CCAGAAGCAG TTTGTGGCCC AGGGTGAGGT GACCCAGGTG 
CCTGATGCCC AAGCTGTGAA ACACTTTCGT GCCGGCCGCG ACAGCTACCT GTGCCTCAGC 
CGCTACATTG GCGACTCCAA GATCCTGCGC TGGGAGGGTA CCCGCTTCTC GGAGGTGCAG 
GCCCTGCCCT CCCGGGGCTC GCTGGCCCTG CAGCCCTTCC TTGTGGGTGG CCGCCGCTAC 
CTGGCACTGG GCAGTGATTT CTCCTTCACC CAGATCTACC AGTGGGATGA GGGACGACAG 
AAGTTTGTAC GGTTCCAGGA GCTGGCTGTG CAGGCTCCTC GGGCCTTCTG CTACATGCCT 
GCTGGGGACG CCCAGCTACT CCTGGCCCCC AGCTTCAAGG GACAGACGCT GGTGTATAGA 
CACATTGTGG TGGATCTCAG TGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LGI3 ( NM_139278.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_644807.1 Homo sapiens leucine rich repeat LGI family member 3 (LGI3), mRNA.

Price & Availability↑

CloneID	OHu25795
Clone ID Related Accession (Same CDS sequence)	NM_139278.3 , NM_139278.2 , NM_139278.4
Accession Version	NM_139278.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1647bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-14
Organism	Homo sapiens(human)
Product	leucine-rich repeat LGI family member 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC105206.8. On Aug 31, 2019 this sequence version replaced NM_139278.3. ##Evidence-Data-START## Transcript exon combination :: AJ487961.1, AJ487518.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000306317.7/ ENSP00000302297.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGGGC TGCGGGCCAG GGGGGGCCCG GGGCCGGGGC TGCTGGCGCT CTCCGCGCTC 
GGCTTCTGCC TCATGCTGCA AGTCAGCGCT AAGAGGCCCC CCAAGACGCC CCCCTGCCCG 
CCCAGCTGCT CTTGCACCAG GGACACCGCC TTCTGCGTGG ACTCAAAGGC GGTGCCCAGG 
AACCTGCCCT CGGAGGTCAT CTCCCTGACC CTGGTGAATG CCGCCTTCTC AGAGATCCAG 
GATGGAGCGT TCTCCCACCT CCCGCTGCTG CAGTTCTTGT TACTCAACTC CAACAAGTTT 
ACACTGATTG GAGACAACGC CTTCACAGGA CTGTCGCACC TGCAGTATCT CTTCATTGAG 
AACAATGACA TCTGGGCACT ATCCAAGTTC ACCTTCCGAG GACTCAAGTC CTTGACTCAC 
CTCTCGCTGG CCAACAATAA CCTGCAGACA CTGCCCAGAG ACATCTTCCG GCCCCTGGAC 
ATCCTGAATG ACTTGGACCT GCGGGGCAAC TCACTCAACT GTGACTGCAA GGTGAAGTGG 
TTGGTGGAGT GGCTGGCACA CACCAACACC ACGGTGGCAC CCATCTACTG CGCCAGCCCG 
CCCCGCTTCC AGGAGCACAA GGTGCAGGAC CTGCCGCTGC GGGAGTTCGA TTGCATCACC 
ACAGATTTTG TGTTGTACCA GACCCTGGCC TTCCCAGCAG TGTCGGCTGA GCCCTTCCTC 
TACTCCAGTG ACCTCTATTT GGCTCTGGCC CAGCCAGGAG TCAGTGCCTG CACCATCCTG 
AAGTGGGACT ATGTTGAGCG GCAGCTTCGA GACTATGATA GAATCCCAGC CCCCTCTGCA 
GTGCACTGCA AGCCGATGGT GGTGGACAGC CAGCTGTACG TGGTCGTGGC CCAGCTGTTT 
GGCGGCTCTT ACATTTACCA CTGGGATCCC AACACCACGC GCTTCACCAG GCTGCAAGAC 
ATTGACCCGC AGCGCGTGCG CAAGCCTAAC GACCTAGAAG CCTTCCGCAT CGACGGTGAC 
TGGTACTTTG CCGTGGCTGA CAGCTCCAAG GCAGGCGCCA CCAGCCTCTA CCGCTGGCAC 
CAGAATGGCT TCTACTCCCA CCAGGCACTG CACCCCTGGC ACCGTGACAC CGACCTGGAG 
TTTGTGGACG GCGAGGGCAA GCCACGGCTG ATTGTGTCCA GCAGCTCCCA GGCACCCGTC 
ATCTATCAGT GGAGTCGCAC CCAGAAGCAG TTTGTGGCCC AGGGTGAGGT GACCCAGGTG 
CCTGATGCCC AAGCTGTGAA ACACTTTCGT GCCGGCCGCG ACAGCTACCT GTGCCTCAGC 
CGCTACATTG GCGACTCCAA GATCCTGCGC TGGGAGGGTA CCCGCTTCTC GGAGGTGCAG 
GCCCTGCCCT CCCGGGGCTC GCTGGCCCTG CAGCCCTTCC TTGTGGGTGG CCGCCGCTAC 
CTGGCACTGG GCAGTGATTT CTCCTTCACC CAGATCTACC AGTGGGATGA GGGACGACAG 
AAGTTTGTAC GGTTCCAGGA GCTGGCTGTG CAGGCTCCTC GGGCCTTCTG CTACATGCCT 
GCTGGGGACG CCCAGCTACT CCTGGCCCCC AGCTTCAAGG GACAGACGCT GGTGTATAGA 
CACATTGTGG TGGATCTCAG TGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_644807.1
CDS	265..1911
Translation	MAGLRARGGPGPGLLALSALGFCLMLQVSAKRPPKTPPCPPSCSCTRDTAFCVDSKAVPRNLPSEVISLTLVNAAFSEIQDGAFSHLPLLQFLLLNSNKFTLIGDNAFTGLSHLQYLFIENNDIWALSKFTFRGLKSLTHLSLANNNLQTLPRDIFRPLDILNDLDLRGNSLNCDCKVKWLVEWLAHTNTTVAPIYCASPPRFQEHKVQDLPLREFDCITTDFVLYQTLAFPAVSAEPFLYSSDLYLALAQPGVSACTILKWDYVERQLRDYDRIPAPSAVHCKPMVVDSQLYVVVAQLFGGSYIYHWDPNTTRFTRLQDIDPQRVRKPNDLEAFRIDGDWYFAVADSSKAGATSLYRWHQNGFYSHQALHPWHRDTDLEFVDGEGKPRLIVSSSSQAPVIYQWSRTQKQFVAQGEVTQVPDAQAVKHFRAGRDSYLCLSRYIGDSKILRWEGTRFSEVQALPSRGSLALQPFLVGGRRYLALGSDFSFTQIYQWDEGRQKFVRFQELAVQAPRAFCYMPAGDAQLLLAPSFKGQTLVYRHIVVDLSA

Target ORF information:

RefSeq Version	NM_139278.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat LGI family member 3 (LGI3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139278.4

ORF Insert Sequence:

ATGGCGGGGC TGCGGGCCAG GGGGGGCCCG GGGCCGGGGC TGCTGGCGCT CTCCGCGCTC 
GGCTTCTGCC TCATGCTGCA AGTCAGCGCT AAGAGGCCCC CCAAGACGCC CCCCTGCCCG 
CCCAGCTGCT CTTGCACCAG GGACACCGCC TTCTGCGTGG ACTCAAAGGC GGTGCCCAGG 
AACCTGCCCT CGGAGGTCAT CTCCCTGACC CTGGTGAATG CCGCCTTCTC AGAGATCCAG 
GATGGAGCGT TCTCCCACCT CCCGCTGCTG CAGTTCTTGT TACTCAACTC CAACAAGTTT 
ACACTGATTG GAGACAACGC CTTCACAGGA CTGTCGCACC TGCAGTATCT CTTCATTGAG 
AACAATGACA TCTGGGCACT ATCCAAGTTC ACCTTCCGAG GACTCAAGTC CTTGACTCAC 
CTCTCGCTGG CCAACAATAA CCTGCAGACA CTGCCCAGAG ACATCTTCCG GCCCCTGGAC 
ATCCTGAATG ACTTGGACCT GCGGGGCAAC TCACTCAACT GTGACTGCAA GGTGAAGTGG 
TTGGTGGAGT GGCTGGCACA CACCAACACC ACGGTGGCAC CCATCTACTG CGCCAGCCCG 
CCCCGCTTCC AGGAGCACAA GGTGCAGGAC CTGCCGCTGC GGGAGTTCGA TTGCATCACC 
ACAGATTTTG TGTTGTACCA GACCCTGGCC TTCCCAGCAG TGTCGGCTGA GCCCTTCCTC 
TACTCCAGTG ACCTCTATTT GGCTCTGGCC CAGCCAGGAG TCAGTGCCTG CACCATCCTG 
AAGTGGGACT ATGTTGAGCG GCAGCTTCGA GACTATGATA GAATCCCAGC CCCCTCTGCA 
GTGCACTGCA AGCCGATGGT GGTGGACAGC CAGCTGTACG TGGTCGTGGC CCAGCTGTTT 
GGCGGCTCTT ACATTTACCA CTGGGATCCC AACACCACGC GCTTCACCAG GCTGCAAGAC 
ATTGACCCGC AGCGCGTGCG CAAGCCTAAC GACCTAGAAG CCTTCCGCAT CGACGGTGAC 
TGGTACTTTG CCGTGGCTGA CAGCTCCAAG GCAGGCGCCA CCAGCCTCTA CCGCTGGCAC 
CAGAATGGCT TCTACTCCCA CCAGGCACTG CACCCCTGGC ACCGTGACAC CGACCTGGAG 
TTTGTGGACG GCGAGGGCAA GCCACGGCTG ATTGTGTCCA GCAGCTCCCA GGCACCCGTC 
ATCTATCAGT GGAGTCGCAC CCAGAAGCAG TTTGTGGCCC AGGGTGAGGT GACCCAGGTG 
CCTGATGCCC AAGCTGTGAA ACACTTTCGT GCCGGCCGCG ACAGCTACCT GTGCCTCAGC 
CGCTACATTG GCGACTCCAA GATCCTGCGC TGGGAGGGTA CCCGCTTCTC GGAGGTGCAG 
GCCCTGCCCT CCCGGGGCTC GCTGGCCCTG CAGCCCTTCC TTGTGGGTGG CCGCCGCTAC 
CTGGCACTGG GCAGTGATTT CTCCTTCACC CAGATCTACC AGTGGGATGA GGGACGACAG 
AAGTTTGTAC GGTTCCAGGA GCTGGCTGTG CAGGCTCCTC GGGCCTTCTG CTACATGCCT 
GCTGGGGACG CCCAGCTACT CCTGGCCCCC AGCTTCAAGG GACAGACGCT GGTGTATAGA 
CACATTGTGG TGGATCTCAG TGCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Leucine-rich glioma inactivated 3: Integrative analyses reveal its potential prognostic role in cancer.
Molecular medicine reports(2017 Dec)
Kwon NS,Baek KJ,Kim DS,Yun HY

Leucine-rich glioma inactivated 3 is a melanogenic cytokine in human skin.
Experimental dermatology23(8)600-2(2014 Aug)
Jeong HS,Jeong YM,Kim J,Lee SH,Choi HR,Park KC,Kim BJ,Baek KJ,Kwon NS,Yun HY,Kim DS

Leucine-rich glioma inactivated 3 promotes HaCaT keratinocyte migration.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society21(4)634-40(2013 Jul-Aug)
Jeong YM,Park WJ,Kim MK,Baek KJ,Kwon NS,Yun HY,Kim DS

Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.
Journal of medical genetics50(5)298-308(2013 May)
Weissglas-Volkov D,Aguilar-Salinas CA,Nikkola E,Deere KA,Cruz-Bautista I,Arellano-Campos O,Mu?oz-Hernandez LL,Gomez-Munguia L,Ordo?ez-S?nchez ML,Reddy PM,Lusis AJ,Matikainen N,Taskinen MR,Riba L,Cantor RM,Sinsheimer JS,Tusie-Luna T,Pajukanta P

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LGI3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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