AK1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	AK1
Entrez Gene ID	203
Full Name	adenylate kinase 1
Synonyms	HTL-S-58j
General protein information	Preferred Names adenylate kinase 1 Names adenylate kinase isoenzyme 1 ATP-AMP transphosphorylase 1 ATP:AMP phosphotransferase adenylate monophosphate kinase myokinase testis secretory sperm binding protein Li 58j
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9q34.11
Summary	This gene encodes an adenylate kinase enzyme involved in energy metabolism and homeostasis of cellular adenine nucleotide ratios in different intracellular compartments. This gene is highly expressed in skeletal muscle, brain and erythrocytes. Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015].
Disorder MIM:	103000
Disorder Html:	Hemolytic anemia due to adenylate kinase deficiency, 612631 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_017014427.1	XP_016869916.1	adenylate kinase isoenzyme 1 isoform X1
NM_001318121.1	NP_001305050.1	adenylate kinase isoenzyme 1 isoform 1
XM_024447440.1	XP_024303208.1	adenylate kinase isoenzyme 1 isoform X3
NM_001318122.1	NP_001305051.1	adenylate kinase isoenzyme 1 isoform 2
NM_001318122.2	NP_001305051.1	adenylate kinase isoenzyme 1 isoform 2
XM_017014428.1	XP_016869917.1	adenylate kinase isoenzyme 1 isoform X1
XM_024447439.1	XP_024303207.1	adenylate kinase isoenzyme 1 isoform X2
NM_000476.2	NP_000467.1	adenylate kinase isoenzyme 1 isoform 1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	AK1	NP_001124519.1
Bos taurus (cattle)	AK1	NP_001013600.1
Arabidopsis thaliana (thale cress)	AT4G25280	NP_194258.2
Homo sapiens (human)	AK1	NP_000467.1
	AK1	XP_002800218.1
Gallus gallus (chicken)	AK1	NP_990440.1
Mus musculus (house mouse)	Ak1	NP_067490.1
Rattus norvegicus (Norway rat)	Ak1	NP_077325.2
Xenopus tropicalis (tropical clawed frog)	ak1	NP_001006817.1
Pan troglodytes (chimpanzee)	AK1	XP_003951582.1
Danio rerio (zebrafish)	ak1	NP_001003993.1
Drosophila melanogaster (fruit fly)	Adk1	NP_729792.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009317	XP_309986.3
Caenorhabditis elegans (roundworm)	F38B2.4	NP_001257141.1

Gene Ontology
Bibliography

Related articles in PubMed

The many isoforms of human adenylate kinases.
Panayiotou C, Solaroli N, Karlsson A
The international journal of biochemistry & cell biology4975-83(2014 Apr)

AMPK, insulin resistance, and the metabolic syndrome.
Ruderman NB, Carling D, Prentki M, Cacicedo JM
The Journal of clinical investigation123(7)2764-72(2013 Jul)

The human adenylate kinase 9 is a nucleoside mono- and diphosphate kinase.
Amiri M, Conserva F, Panayiotou C, Karlsson A, Solaroli N
The international journal of biochemistry & cell biology45(5)925-31(2013 May)

Ak(1) genetic polymorphism and season of conception.
Gloria-Bottini F, Neri A, Pietropolli A, Bottini E, Magrini A
European journal of obstetrics, gynecology, and reproductive biology166(2)161-3(2013 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Studies indicate that the preferred substrate and phosphate donor of all adenylate kinases are AMP and ATP respectively.
Title: The many isoforms of human adenylate kinases.

Dysregulation of AMPK is both a pathogenic factor for these disorders in humans and a target for their prevention and therapy. [Review]
Title: AMPK, insulin resistance, and the metabolic syndrome.

Ak(1)2-1 phenotype is more frequent in males conceived in the summer-autumn period than in those conceived in winter-spring, and this association depends on maternal Ak(1) phenotype.
Title: Ak(1) genetic polymorphism and season of conception.

identified hitherto unrecognized soluble forms of AK1 and NTPDase1/CD39 that contribute in the active cycling between the principal platelet-recruiting agent ADP and other circulating nucleotides
Title: Metabolism of circulating ADP in the bloodstream is mediated via integrated actions of soluble adenylate kinase-1 and NTPDase1/CD39 activities.

Data indicate that the neuronal adenylate kinase-1 (AK1) is induced by Abeta(42) to increase abnormal tau phosphorylation via AMPK-GSK3beta and contributes to tau-mediated neurodegeneration.
Title: Neuropathogenic role of adenylate kinase-1 in A?-mediated tau phosphorylation via AMPK and GSK3?.

The following AK1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AK1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18176	NM_000476.2 Latest version!	Homo sapiens adenylate kinase 1 (AK1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu18176	NM_001318121.1 Latest version!	Homo sapiens adenylate kinase 1 (AK1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu56220	XM_017014427.1 Latest version!	Homo sapiens adenylate kinase 1 (AK1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu56220	XM_017014428.1 Latest version!	Homo sapiens adenylate kinase 1 (AK1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu102025	NM_001318122.1 Latest version!	Homo sapiens adenylate kinase 1 (AK1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu43063	NM_001318122.2 Latest version!	Homo sapiens adenylate kinase 1 (AK1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu106112	XM_024447439.1 Latest version!	Homo sapiens adenylate kinase 1 (AK1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu56221	XM_024447440.1 Latest version!	Homo sapiens adenylate kinase 1 (AK1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

AK1 ( NM_001318121.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001305050.1 Homo sapiens adenylate kinase 1 (AK1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu18176
Clone ID Related Accession (Same CDS sequence)	NM_001318121.1 , NM_000476.2
Accession Version	NM_001318121.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 585bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-24
Organism	Homo sapiens(human)
Product	adenylate kinase isoenzyme 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CR975542.1 and AL157935.28. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CR975542.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAGAGA AGCTGAAGAA AACCAAGATC ATCTTTGTGG TGGGTGGGCC TGGCTCAGGG 
AAGGGCACCC AGTGTGAGAA GATCGTGCAG AAGTATGGCT ACACCCACCT CTCCACCGGG 
GACCTCCTGC GGTCCGAGGT CAGCTCAGGC TCGGCCAGGG GCAAGAAGCT GTCGGAAATC 
ATGGAGAAGG GGCAGCTGGT TCCACTGGAG ACAGTGTTGG ACATGCTCCG GGATGCCATG 
GTGGCCAAAG TCAATACTTC CAAAGGCTTC CTGATTGATG GCTACCCGCG GGAGGTGCAG 
CAAGGAGAAG AGTTTGAGCG ACGGATTGGA CAGCCCACAC TGCTGCTGTA TGTGGACGCA 
GGCCCTGAGA CCATGACCCA GCGGCTCTTG AAACGTGGAG AGACCAGCGG GCGTGTGGAC 
GACAATGAGG AGACCATCAA AAAGCGGCTG GAGACCTATT ACAAGGCCAC AGAACCCGTC 
ATCGCCTTCT ATGAGAAACG TGGCATTGTG CGCAAGGTCA ACGCTGAGGG CTCCGTGGAC 
AGTGTCTTCT CCCAGGTCTG CACCCACCTG GACGCCCTAA AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001305050.1
CDS	141..725
Translation	MEEKLKKTKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRSEVSSGSARGKKLSEIMEKGQLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLLLYVDAGPETMTQRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLDALK

Target ORF information:

RefSeq Version	NM_001318121.1
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate kinase 1 (AK1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001318121.1

ORF Insert Sequence:

ATGGAAGAGA AGCTGAAGAA AACCAAGATC ATCTTTGTGG TGGGTGGGCC TGGCTCAGGG 
AAGGGCACCC AGTGTGAGAA GATCGTGCAG AAGTATGGCT ACACCCACCT CTCCACCGGG 
GACCTCCTGC GGTCCGAGGT CAGCTCAGGC TCGGCCAGGG GCAAGAAGCT GTCGGAAATC 
ATGGAGAAGG GGCAGCTGGT TCCACTGGAG ACAGTGTTGG ACATGCTCCG GGATGCCATG 
GTGGCCAAAG TCAATACTTC CAAAGGCTTC CTGATTGATG GCTACCCGCG GGAGGTGCAG 
CAAGGAGAAG AGTTTGAGCG ACGGATTGGA CAGCCCACAC TGCTGCTGTA TGTGGACGCA 
GGCCCTGAGA CCATGACCCA GCGGCTCTTG AAACGTGGAG AGACCAGCGG GCGTGTGGAC 
GACAATGAGG AGACCATCAA AAAGCGGCTG GAGACCTATT ACAAGGCCAC AGAACCCGTC 
ATCGCCTTCT ATGAGAAACG TGGCATTGTG CGCAAGGTCA ACGCTGAGGG CTCCGTGGAC 
AGTGTCTTCT CCCAGGTCTG CACCCACCTG GACGCCCTAA AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AK1 ( NM_000476.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_000467.1 Homo sapiens adenylate kinase 1 (AK1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18176
Clone ID Related Accession (Same CDS sequence)	NM_001318121.1 , NM_000476.2
Accession Version	NM_000476.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 585bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Homo sapiens(human)
Product	adenylate kinase isoenzyme 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA077967.1, BC100022.1 and AL157935.28. This sequence is a reference standard in the RefSeqGene project. On Jun 28, 2007 this sequence version replaced NM_000476.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the shorter isoform (1). Both variants 1 and 2 encode the same protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EU794628.1, SRR1660803.245772.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2147920 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAAGAGA AGCTGAAGAA AACCAAGATC ATCTTTGTGG TGGGTGGGCC TGGCTCAGGG 
AAGGGCACCC AGTGTGAGAA GATCGTGCAG AAGTATGGCT ACACCCACCT CTCCACCGGG 
GACCTCCTGC GGTCCGAGGT CAGCTCAGGC TCGGCCAGGG GCAAGAAGCT GTCGGAAATC 
ATGGAGAAGG GGCAGCTGGT TCCACTGGAG ACAGTGTTGG ACATGCTCCG GGATGCCATG 
GTGGCCAAAG TCAATACTTC CAAAGGCTTC CTGATTGATG GCTACCCGCG GGAGGTGCAG 
CAAGGAGAAG AGTTTGAGCG ACGGATTGGA CAGCCCACAC TGCTGCTGTA TGTGGACGCA 
GGCCCTGAGA CCATGACCCA GCGGCTCTTG AAACGTGGAG AGACCAGCGG GCGTGTGGAC 
GACAATGAGG AGACCATCAA AAAGCGGCTG GAGACCTATT ACAAGGCCAC AGAACCCGTC 
ATCGCCTTCT ATGAGAAACG TGGCATTGTG CGCAAGGTCA ACGCTGAGGG CTCCGTGGAC 
AGTGTCTTCT CCCAGGTCTG CACCCACCTG GACGCCCTAA AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000467.1
CDS	154..738
Translation	MEEKLKKTKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRSEVSSGSARGKKLSEIMEKGQLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLLLYVDAGPETMTQRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLDALK

Target ORF information:

RefSeq Version	NM_000476.2
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate kinase 1 (AK1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000476.2

ORF Insert Sequence:

ATGGAAGAGA AGCTGAAGAA AACCAAGATC ATCTTTGTGG TGGGTGGGCC TGGCTCAGGG 
AAGGGCACCC AGTGTGAGAA GATCGTGCAG AAGTATGGCT ACACCCACCT CTCCACCGGG 
GACCTCCTGC GGTCCGAGGT CAGCTCAGGC TCGGCCAGGG GCAAGAAGCT GTCGGAAATC 
ATGGAGAAGG GGCAGCTGGT TCCACTGGAG ACAGTGTTGG ACATGCTCCG GGATGCCATG 
GTGGCCAAAG TCAATACTTC CAAAGGCTTC CTGATTGATG GCTACCCGCG GGAGGTGCAG 
CAAGGAGAAG AGTTTGAGCG ACGGATTGGA CAGCCCACAC TGCTGCTGTA TGTGGACGCA 
GGCCCTGAGA CCATGACCCA GCGGCTCTTG AAACGTGGAG AGACCAGCGG GCGTGTGGAC 
GACAATGAGG AGACCATCAA AAAGCGGCTG GAGACCTATT ACAAGGCCAC AGAACCCGTC 
ATCGCCTTCT ATGAGAAACG TGGCATTGTG CGCAAGGTCA ACGCTGAGGG CTCCGTGGAC 
AGTGTCTTCT CCCAGGTCTG CACCCACCTG GACGCCCTAA AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AK1 ( XM_017014427.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869916.1 Homo sapiens adenylate kinase 1 (AK1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu56220
Clone ID Related Accession (Same CDS sequence)	XM_017014427.1 , XM_017014428.1
Accession Version	XM_017014427.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 585bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	adenylate kinase isoenzyme 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGAGA AGCTGAAGAA AACCAAGATC ATCTTTGTGG TGGGTGGGCC TGGCTCAGGG 
AAGGGCACCC AGTGTGAGAA GATCGTGCAG AAGTATGGCT ACACCCACCT CTCCACCGGG 
GACCTCCTGC GGTCCGAGGT CAGCTCAGGC TCGGCCAGGG GCAAGAAGCT GTCGGAAATC 
ATGGAGAAGG GGCAGCTGGT TCCACTGGAG ACAGTGTTGG ACATGCTCCG GGATGCCATG 
GTGGCCAAAG TCAATACTTC CAAAGGCTTC CTGATTGATG GCTACCCGCG GGAGGTGCAG 
CAAGGAGAAG AGTTTGAGCG ACGGATTGGA CAGCCCACAC TGCTGCTGTA TGTGGACGCA 
GGCCCTGAGA CCATGACCCA GCGGCTCTTG AAACGTGGAG AGACCAGCGG GCGTGTGGAC 
GACAATGAGG AGACCATCAA AAAGCGGCTG GAGACCTATT ACAAGGCCAC AGAACCTGTC 
ATCGCCTTCT ATGAGAAACG TGGCATTGTG CGCAAGGTCA ACGCTGAGGG CTCCGTGGAC 
AGTGTCTTCT CCCAGGTCTG CACCCACCTG GACGCCCTAA AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869916.1
CDS	1597..2181
Translation	MEEKLKKTKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRSEVSSGSARGKKLSEIMEKGQLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLLLYVDAGPETMTQRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLDALK

Target ORF information:

RefSeq Version	XM_017014427.1
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate kinase 1 (AK1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017014427.1

ORF Insert Sequence:

ATGGAAGAGA AGCTGAAGAA AACCAAGATC ATCTTTGTGG TGGGTGGGCC TGGCTCAGGG 
AAGGGCACCC AGTGTGAGAA GATCGTGCAG AAGTATGGCT ACACCCACCT CTCCACCGGG 
GACCTCCTGC GGTCCGAGGT CAGCTCAGGC TCGGCCAGGG GCAAGAAGCT GTCGGAAATC 
ATGGAGAAGG GGCAGCTGGT TCCACTGGAG ACAGTGTTGG ACATGCTCCG GGATGCCATG 
GTGGCCAAAG TCAATACTTC CAAAGGCTTC CTGATTGATG GCTACCCGCG GGAGGTGCAG 
CAAGGAGAAG AGTTTGAGCG ACGGATTGGA CAGCCCACAC TGCTGCTGTA TGTGGACGCA 
GGCCCTGAGA CCATGACCCA GCGGCTCTTG AAACGTGGAG AGACCAGCGG GCGTGTGGAC 
GACAATGAGG AGACCATCAA AAAGCGGCTG GAGACCTATT ACAAGGCCAC AGAACCTGTC 
ATCGCCTTCT ATGAGAAACG TGGCATTGTG CGCAAGGTCA ACGCTGAGGG CTCCGTGGAC 
AGTGTCTTCT CCCAGGTCTG CACCCACCTG GACGCCCTAA AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AK1 ( XM_017014428.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869917.1 Homo sapiens adenylate kinase 1 (AK1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu56220
Clone ID Related Accession (Same CDS sequence)	XM_017014427.1 , XM_017014428.1
Accession Version	XM_017014428.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 585bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	adenylate kinase isoenzyme 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAAGAGA AGCTGAAGAA AACCAAGATC ATCTTTGTGG TGGGTGGGCC TGGCTCAGGG 
AAGGGCACCC AGTGTGAGAA GATCGTGCAG AAGTATGGCT ACACCCACCT CTCCACCGGG 
GACCTCCTGC GGTCCGAGGT CAGCTCAGGC TCGGCCAGGG GCAAGAAGCT GTCGGAAATC 
ATGGAGAAGG GGCAGCTGGT TCCACTGGAG ACAGTGTTGG ACATGCTCCG GGATGCCATG 
GTGGCCAAAG TCAATACTTC CAAAGGCTTC CTGATTGATG GCTACCCGCG GGAGGTGCAG 
CAAGGAGAAG AGTTTGAGCG ACGGATTGGA CAGCCCACAC TGCTGCTGTA TGTGGACGCA 
GGCCCTGAGA CCATGACCCA GCGGCTCTTG AAACGTGGAG AGACCAGCGG GCGTGTGGAC 
GACAATGAGG AGACCATCAA AAAGCGGCTG GAGACCTATT ACAAGGCCAC AGAACCTGTC 
ATCGCCTTCT ATGAGAAACG TGGCATTGTG CGCAAGGTCA ACGCTGAGGG CTCCGTGGAC 
AGTGTCTTCT CCCAGGTCTG CACCCACCTG GACGCCCTAA AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869917.1
CDS	501..1085
Translation	MEEKLKKTKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRSEVSSGSARGKKLSEIMEKGQLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLLLYVDAGPETMTQRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLDALK

Target ORF information:

RefSeq Version	XM_017014428.1
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate kinase 1 (AK1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017014428.1

ORF Insert Sequence:

ATGGAAGAGA AGCTGAAGAA AACCAAGATC ATCTTTGTGG TGGGTGGGCC TGGCTCAGGG 
AAGGGCACCC AGTGTGAGAA GATCGTGCAG AAGTATGGCT ACACCCACCT CTCCACCGGG 
GACCTCCTGC GGTCCGAGGT CAGCTCAGGC TCGGCCAGGG GCAAGAAGCT GTCGGAAATC 
ATGGAGAAGG GGCAGCTGGT TCCACTGGAG ACAGTGTTGG ACATGCTCCG GGATGCCATG 
GTGGCCAAAG TCAATACTTC CAAAGGCTTC CTGATTGATG GCTACCCGCG GGAGGTGCAG 
CAAGGAGAAG AGTTTGAGCG ACGGATTGGA CAGCCCACAC TGCTGCTGTA TGTGGACGCA 
GGCCCTGAGA CCATGACCCA GCGGCTCTTG AAACGTGGAG AGACCAGCGG GCGTGTGGAC 
GACAATGAGG AGACCATCAA AAAGCGGCTG GAGACCTATT ACAAGGCCAC AGAACCTGTC 
ATCGCCTTCT ATGAGAAACG TGGCATTGTG CGCAAGGTCA ACGCTGAGGG CTCCGTGGAC 
AGTGTCTTCT CCCAGGTCTG CACCCACCTG GACGCCCTAA AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AK1 ( NM_001318122.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001305051.1 Homo sapiens adenylate kinase 1 (AK1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu102025
Clone ID Related Accession (Same CDS sequence)	NM_001318122.1
Accession Version	NM_001318122.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 633bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-25
Organism	Homo sapiens(human)
Product	adenylate kinase isoenzyme 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY024815.1, BG772183.1 and AL157935.28. On Dec 24, 2015 this sequence version replaced XM_005251786.2. Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at an alternate start site, compared to variant 1. It encodes isoform 2 which is longer and has a distinct N-terminus compared to variant 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BG772183.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCTGCT GCTCCTCGAG TGACCCCCGC AGAGAAGACG ATCTGAGAGC CAGAGAGAAG 
CTGAAGAAAA CCAAGATCAT CTTTGTGGTG GGTGGGCCTG GCTCAGGGAA GGGCACCCAG 
TGTGAGAAGA TCGTGCAGAA GTATGGCTAC ACCCACCTCT CCACCGGGGA CCTCCTGCGG 
TCCGAGGTCA GCTCAGGCTC GGCCAGGGGC AAGAAGCTGT CGGAAATCAT GGAGAAGGGG 
CAGCTGGTTC CACTGGAGAC AGTGTTGGAC ATGCTCCGGG ATGCCATGGT GGCCAAAGTC 
AATACTTCCA AAGGCTTCCT GATTGATGGC TACCCGCGGG AGGTGCAGCA AGGAGAAGAG 
TTTGAGCGAC GGATTGGACA GCCCACACTG CTGCTGTATG TGGACGCAGG CCCTGAGACC 
ATGACCCAGC GGCTCTTGAA ACGTGGAGAG ACCAGCGGGC GTGTGGACGA CAATGAGGAG 
ACCATCAAAA AGCGGCTGGA GACCTATTAC AAGGCCACAG AACCCGTCAT CGCCTTCTAT 
GAGAAACGTG GCATTGTGCG CAAGGTCAAC GCTGAGGGCT CCGTGGACAG TGTCTTCTCC 
CAGGTCTGCA CCCACCTGGA CGCCCTAAAG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001305051.1
CDS	101..733
Translation	MGCCSSSDPRREDDLRAREKLKKTKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRSEVSSGSARGKKLSEIMEKGQLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLLLYVDAGPETMTQRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLDALK

Target ORF information:

RefSeq Version	NM_001318122.1
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate kinase 1 (AK1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001318122.1

ORF Insert Sequence:

ATGGGCTGCT GCTCCTCGAG TGACCCCCGC AGAGAAGACG ATCTGAGAGC CAGAGAGAAG 
CTGAAGAAAA CCAAGATCAT CTTTGTGGTG GGTGGGCCTG GCTCAGGGAA GGGCACCCAG 
TGTGAGAAGA TCGTGCAGAA GTATGGCTAC ACCCACCTCT CCACCGGGGA CCTCCTGCGG 
TCCGAGGTCA GCTCAGGCTC GGCCAGGGGC AAGAAGCTGT CGGAAATCAT GGAGAAGGGG 
CAGCTGGTTC CACTGGAGAC AGTGTTGGAC ATGCTCCGGG ATGCCATGGT GGCCAAAGTC 
AATACTTCCA AAGGCTTCCT GATTGATGGC TACCCGCGGG AGGTGCAGCA AGGAGAAGAG 
TTTGAGCGAC GGATTGGACA GCCCACACTG CTGCTGTATG TGGACGCAGG CCCTGAGACC 
ATGACCCAGC GGCTCTTGAA ACGTGGAGAG ACCAGCGGGC GTGTGGACGA CAATGAGGAG 
ACCATCAAAA AGCGGCTGGA GACCTATTAC AAGGCCACAG AACCCGTCAT CGCCTTCTAT 
GAGAAACGTG GCATTGTGCG CAAGGTCAAC GCTGAGGGCT CCGTGGACAG TGTCTTCTCC 
CAGGTCTGCA CCCACCTGGA CGCCCTAAAG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AK1 ( NM_001318122.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001305051.1 Homo sapiens adenylate kinase 1 (AK1), transcript variant 3, mRNA.

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CloneID	OHu43063
Clone ID Related Accession (Same CDS sequence)	NM_001318122.2
Accession Version	NM_001318122.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 633bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-29
Organism	Homo sapiens(human)
Product	adenylate kinase isoenzyme 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL157935.28. On Jun 2, 2019 this sequence version replaced NM_001318122.1. Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at an alternate start site, compared to variant 1. It encodes isoform 2 which is longer and has a distinct N-terminus compared to variant 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7410570.437726.1, SRR7410570.437709.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCTGCT GCTCCTCGAG TGACCCCCGC AGAGAAGACG ATCTGAGAGC CAGAGAGAAG 
CTGAAGAAAA CCAAGATCAT CTTTGTGGTG GGTGGGCCTG GCTCAGGGAA GGGCACCCAG 
TGTGAGAAGA TCGTGCAGAA GTATGGCTAC ACCCACCTCT CCACCGGGGA CCTCCTGCGG 
TCCGAGGTCA GCTCAGGCTC GGCCAGGGGC AAGAAGCTGT CGGAAATCAT GGAGAAGGGG 
CAGCTGGTTC CACTGGAGAC AGTGTTGGAC ATGCTCCGGG ATGCCATGGT GGCCAAAGTC 
AATACTTCCA AAGGCTTCCT GATTGATGGC TACCCGCGGG AGGTGCAGCA AGGAGAAGAG 
TTTGAGCGAC GGATTGGACA GCCCACACTG CTGCTGTATG TGGACGCAGG CCCTGAGACC 
ATGACCCAGC GGCTCTTGAA ACGTGGAGAG ACCAGCGGGC GTGTGGACGA CAATGAGGAG 
ACCATCAAAA AGCGGCTGGA GACCTATTAC AAGGCCACAG AACCTGTCAT CGCCTTCTAT 
GAGAAACGTG GCATTGTGCG CAAGGTCAAC GCTGAGGGCT CCGTGGACAG TGTCTTCTCC 
CAGGTCTGCA CCCACCTGGA CGCCCTAAAG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001305051.1
CDS	33..665
Translation	MGCCSSSDPRREDDLRAREKLKKTKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRSEVSSGSARGKKLSEIMEKGQLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLLLYVDAGPETMTQRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLDALK

Target ORF information:

RefSeq Version	NM_001318122.2
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate kinase 1 (AK1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001318122.2

ORF Insert Sequence:

ATGGGCTGCT GCTCCTCGAG TGACCCCCGC AGAGAAGACG ATCTGAGAGC CAGAGAGAAG 
CTGAAGAAAA CCAAGATCAT CTTTGTGGTG GGTGGGCCTG GCTCAGGGAA GGGCACCCAG 
TGTGAGAAGA TCGTGCAGAA GTATGGCTAC ACCCACCTCT CCACCGGGGA CCTCCTGCGG 
TCCGAGGTCA GCTCAGGCTC GGCCAGGGGC AAGAAGCTGT CGGAAATCAT GGAGAAGGGG 
CAGCTGGTTC CACTGGAGAC AGTGTTGGAC ATGCTCCGGG ATGCCATGGT GGCCAAAGTC 
AATACTTCCA AAGGCTTCCT GATTGATGGC TACCCGCGGG AGGTGCAGCA AGGAGAAGAG 
TTTGAGCGAC GGATTGGACA GCCCACACTG CTGCTGTATG TGGACGCAGG CCCTGAGACC 
ATGACCCAGC GGCTCTTGAA ACGTGGAGAG ACCAGCGGGC GTGTGGACGA CAATGAGGAG 
ACCATCAAAA AGCGGCTGGA GACCTATTAC AAGGCCACAG AACCTGTCAT CGCCTTCTAT 
GAGAAACGTG GCATTGTGCG CAAGGTCAAC GCTGAGGGCT CCGTGGACAG TGTCTTCTCC 
CAGGTCTGCA CCCACCTGGA CGCCCTAAAG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AK1 ( XM_024447439.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024303207.1 Homo sapiens adenylate kinase 1 (AK1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu106112
Clone ID Related Accession (Same CDS sequence)	XM_024447439.1
Accession Version	XM_024447439.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 564bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	adenylate kinase isoenzyme 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAATGGGT GGGCGTTTGC AGGTGGGCCT GGCTCAGGGA AGGGCACCCA GTGTGAGAAG 
ATCGTGCAGA AGTATGGCTA CACCCACCTC TCCACCGGGG ACCTCCTGCG GTCCGAGGTC 
AGCTCAGGCT CGGCCAGGGG CAAGAAGCTG TCGGAAATCA TGGAGAAGGG GCAGCTGGTT 
CCACTGGAGA CAGTGTTGGA CATGCTCCGG GATGCCATGG TGGCCAAAGT CAATACTTCC 
AAAGGCTTCC TGATTGATGG CTACCCGCGG GAGGTGCAGC AAGGAGAAGA GTTTGAGCGA 
CGGATTGGAC AGCCCACACT GCTGCTGTAT GTGGACGCAG GCCCTGAGAC CATGACCCAG 
CGGCTCTTGA AACGTGGAGA GACCAGCGGG CGTGTGGACG ACAATGAGGA GACCATCAAA 
AAGCGGCTGG AGACCTATTA CAAGGCCACA GAACCTGTCA TCGCCTTCTA TGAGAAACGT 
GGCATTGTGC GCAAGGTCAA CGCTGAGGGC TCCGTGGACA GTGTCTTCTC CCAGGTCTGC 
ACCCACCTGG ACGCCCTAAA GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024303207.1
CDS	398..961
Translation	MNGWAFAGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRSEVSSGSARGKKLSEIMEKGQLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLLLYVDAGPETMTQRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLDALK

Target ORF information:

RefSeq Version	XM_024447439.1
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate kinase 1 (AK1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024447439.1

ORF Insert Sequence:

ATGAATGGGT GGGCGTTTGC AGGTGGGCCT GGCTCAGGGA AGGGCACCCA GTGTGAGAAG 
ATCGTGCAGA AGTATGGCTA CACCCACCTC TCCACCGGGG ACCTCCTGCG GTCCGAGGTC 
AGCTCAGGCT CGGCCAGGGG CAAGAAGCTG TCGGAAATCA TGGAGAAGGG GCAGCTGGTT 
CCACTGGAGA CAGTGTTGGA CATGCTCCGG GATGCCATGG TGGCCAAAGT CAATACTTCC 
AAAGGCTTCC TGATTGATGG CTACCCGCGG GAGGTGCAGC AAGGAGAAGA GTTTGAGCGA 
CGGATTGGAC AGCCCACACT GCTGCTGTAT GTGGACGCAG GCCCTGAGAC CATGACCCAG 
CGGCTCTTGA AACGTGGAGA GACCAGCGGG CGTGTGGACG ACAATGAGGA GACCATCAAA 
AAGCGGCTGG AGACCTATTA CAAGGCCACA GAACCTGTCA TCGCCTTCTA TGAGAAACGT 
GGCATTGTGC GCAAGGTCAA CGCTGAGGGC TCCGTGGACA GTGTCTTCTC CCAGGTCTGC 
ACCCACCTGG ACGCCCTAAA GTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AK1 ( XM_024447440.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024303208.1 Homo sapiens adenylate kinase 1 (AK1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu56221
Clone ID Related Accession (Same CDS sequence)	XM_024447440.1
Accession Version	XM_024447440.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 405bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	adenylate kinase isoenzyme 1 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAAGG GGCAGCTGGT TCCACTGGAG ACAGTGTTGG ACATGCTCCG GGATGCCATG 
GTGGCCAAAG TCAATACTTC CAAAGGCTTC CTGATTGATG GCTACCCGCG GGAGGTGCAG 
CAAGGAGAAG AGTTTGAGCG ACGGATTGGA CAGCCCACAC TGCTGCTGTA TGTGGACGCA 
GGCCCTGAGA CCATGACCCA GCGGCTCTTG AAACGTGGAG AGACCAGCGG GCGTGTGGAC 
GACAATGAGG AGACCATCAA AAAGCGGCTG GAGACCTATT ACAAGGCCAC AGAACCTGTC 
ATCGCCTTCT ATGAGAAACG TGGCATTGTG CGCAAGGTCA ACGCTGAGGG CTCCGTGGAC 
AGTGTCTTCT CCCAGGTCTG CACCCACCTG GACGCCCTAA AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024303208.1
CDS	385..789
Translation	MEKGQLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLLLYVDAGPETMTQRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLDALK

Target ORF information:

RefSeq Version	XM_024447440.1
Organism	Homo sapiens(human)
Definition	Homo sapiens adenylate kinase 1 (AK1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024447440.1

ORF Insert Sequence:

ATGGAGAAGG GGCAGCTGGT TCCACTGGAG ACAGTGTTGG ACATGCTCCG GGATGCCATG 
GTGGCCAAAG TCAATACTTC CAAAGGCTTC CTGATTGATG GCTACCCGCG GGAGGTGCAG 
CAAGGAGAAG AGTTTGAGCG ACGGATTGGA CAGCCCACAC TGCTGCTGTA TGTGGACGCA 
GGCCCTGAGA CCATGACCCA GCGGCTCTTG AAACGTGGAG AGACCAGCGG GCGTGTGGAC 
GACAATGAGG AGACCATCAA AAAGCGGCTG GAGACCTATT ACAAGGCCAC AGAACCTGTC 
ATCGCCTTCT ATGAGAAACG TGGCATTGTG CGCAAGGTCA ACGCTGAGGG CTCCGTGGAC 
AGTGTCTTCT CCCAGGTCTG CACCCACCTG GACGCCCTAA AGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The many isoforms of human adenylate kinases.
The international journal of biochemistry & cell biology4975-83(2014 Apr)
Panayiotou C,Solaroli N,Karlsson A

AMPK, insulin resistance, and the metabolic syndrome.
The Journal of clinical investigation123(7)2764-72(2013 Jul)
Ruderman NB,Carling D,Prentki M,Cacicedo JM

The human adenylate kinase 9 is a nucleoside mono- and diphosphate kinase.
The international journal of biochemistry & cell biology45(5)925-31(2013 May)
Amiri M,Conserva F,Panayiotou C,Karlsson A,Solaroli N

Ak(1) genetic polymorphism and season of conception.
European journal of obstetrics, gynecology, and reproductive biology166(2)161-3(2013 Feb)
Gloria-Bottini F,Neri A,Pietropolli A,Bottini E,Magrini A

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AK1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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