EN1 cDNA ORF clone, Homo sapiens(human)

The following EN1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EN1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu18410 NM_001426.4
Latest version!
Homo sapiens engrailed homeobox 1 (EN1), mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$159.50-$223.30
$319.00
View Old Accession Versions >>
OHu18410 NM_001426.3 Homo sapiens engrailed homeobox 1 (EN1), mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$159.50-$223.30
$319.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OHu18410
    Clone ID Related Accession (Same CDS sequence) NM_001426.3 , NM_001426.4
    Accession Version NM_001426.3 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1179bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-05-03
    Organism Homo sapiens(human)
    Product homeobox protein engrailed-1
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC012665.8. This sequence is a reference standard in the RefSeqGene project. On Feb 23, 2007 this sequence version replaced NM_001426.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGGAAGAAC AGCAGCCGGA ACCTAAAAGT CAGCGCGACT CGGCCCTCGG CGCGGCGGCG 
    GCGGCGACTC CGGGCGGCCT CAGCCTGAGC CTCAGTCCGG GCGCCAGCGG CAGCAGCGGC
    AGCGGCAGCG ATGGAGACAG CGTGCCGGTG TCCCCGCAGC CTGCGCCCCC CTCGCCGCCC
    GCGGCGCCTT GCCTGCCGCC CCTGGCCCAC CACCCGCACC TCCCCCCACA CCCCCCGCCC
    CCGCCGCCTC AGCATCTCGC GGCGCCTGCT CACCAGCCGC AGCCAGCGGC CCAGCTGCAC
    CGCACCACCA ACTTTTTCAT CGACAACATC CTGAGGCCGG ACTTCGGCTG CAAAAAGGAG
    CAGCCGCCAC CGCAGCTTCT GGTGGCTGCG GCGGCCAGAG GAGGCGCAGG AGGAGGAGGC
    CGGGTCGAGC GTGACAGAGG CCAGACTGCC GCAGGTAGAG ACCCTGTCCA CCCGTTGGGC
    ACCCGGGCGC CAGGCGCTGC CTCGCTCCTG TGCGCCCCGG ACGCGAACTG TGGCCCACCC
    GACGGCTCCC AGCCAGCCGC CGCCGGCGCG GGCGCGTCTA AAGCTGGGAA CCCGGCTGCG
    GCGGCGGCGG CGGCCGCGGC GGCAGTGGCG GCGGCGGCGG CGGCCGCAGC AGCCAAGCCC
    TCGGACACCG GTGGCGGCGG CAGTGGAGGC GGCGCGGGGA GCCCCGGAGC GCAGGGCACC
    AAATACCCGG AGCACGGCAA CCCGGCTATC CTACTTATGG GCTCAGCCAA CGGCGGGCCC
    GTGGTCAAAA CTGACTCGCA GCAGCCTCTC GTATGGCCCG CCTGGGTGTA CTGCACACGT
    TATTCGGATC GTCCATCCTC CGGTCCGCGC ACCAGGAAGC TGAAGAAGAA GAAGAACGAG
    AAGGAGGACA AGCGGCCGCG GACCGCGTTC ACGGCCGAGC AGCTGCAGAG ACTCAAGGCG
    GAGTTCCAGG CAAACCGCTA CATCACGGAG CAGCGGCGGC AGACCCTGGC CCAGGAACTC
    AGCCTCAACG AGTCCCAGAT CAAGATCTGG TTCCAGAACA AGCGCGCCAA GATCAAGAAA
    GCCACAGGCA TCAAGAACGG CCTGGCGCTG CACCTCATGG CCCAGGGACT GTACAACCAC
    TCCACCACCA CGGTCCAGGA CAAAGACGAG AGCGAGTAG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001417.3
    CDS1017..2195
    Translation

    Target ORF information:

    RefSeq Version NM_001426.3
    Organism Homo sapiens(human)
    Definition Homo sapiens engrailed homeobox 1 (EN1), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001426.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGGAAGAAC AGCAGCCGGA ACCTAAAAGT CAGCGCGACT CGGCCCTCGG CGCGGCGGCG 
    GCGGCGACTC CGGGCGGCCT CAGCCTGAGC CTCAGTCCGG GCGCCAGCGG CAGCAGCGGC
    AGCGGCAGCG ATGGAGACAG CGTGCCGGTG TCCCCGCAGC CTGCGCCCCC CTCGCCGCCC
    GCGGCGCCTT GCCTGCCGCC CCTGGCCCAC CACCCGCACC TCCCCCCACA CCCCCCGCCC
    CCGCCGCCTC AGCATCTCGC GGCGCCTGCT CACCAGCCGC AGCCAGCGGC CCAGCTGCAC
    CGCACCACCA ACTTTTTCAT CGACAACATC CTGAGGCCGG ACTTCGGCTG CAAAAAGGAG
    CAGCCGCCAC CGCAGCTTCT GGTGGCTGCG GCGGCCAGAG GAGGCGCAGG AGGAGGAGGC
    CGGGTCGAGC GTGACAGAGG CCAGACTGCC GCAGGTAGAG ACCCTGTCCA CCCGTTGGGC
    ACCCGGGCGC CAGGCGCTGC CTCGCTCCTG TGCGCCCCGG ACGCGAACTG TGGCCCACCC
    GACGGCTCCC AGCCAGCCGC CGCCGGCGCG GGCGCGTCTA AAGCTGGGAA CCCGGCTGCG
    GCGGCGGCGG CGGCCGCGGC GGCAGTGGCG GCGGCGGCGG CGGCCGCAGC AGCCAAGCCC
    TCGGACACCG GTGGCGGCGG CAGTGGAGGC GGCGCGGGGA GCCCCGGAGC GCAGGGCACC
    AAATACCCGG AGCACGGCAA CCCGGCTATC CTACTTATGG GCTCAGCCAA CGGCGGGCCC
    GTGGTCAAAA CTGACTCGCA GCAGCCTCTC GTATGGCCCG CCTGGGTGTA CTGCACACGT
    TATTCGGATC GTCCATCCTC CGGTCCGCGC ACCAGGAAGC TGAAGAAGAA GAAGAACGAG
    AAGGAGGACA AGCGGCCGCG GACCGCGTTC ACGGCCGAGC AGCTGCAGAG ACTCAAGGCG
    GAGTTCCAGG CAAACCGCTA CATCACGGAG CAGCGGCGGC AGACCCTGGC CCAGGAACTC
    AGCCTCAACG AGTCCCAGAT CAAGATCTGG TTCCAGAACA AGCGCGCCAA GATCAAGAAA
    GCCACAGGCA TCAAGAACGG CCTGGCGCTG CACCTCATGG CCCAGGGACT GTACAACCAC
    TCCACCACCA CGGTCCAGGA CAAAGACGAG AGCGAGTAG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu18410
    Clone ID Related Accession (Same CDS sequence) NM_001426.3 , NM_001426.4
    Accession Version NM_001426.4 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1179bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-09-14
    Organism Homo sapiens(human)
    Product homeobox protein engrailed-1
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC012665.8. This sequence is a reference standard in the RefSeqGene project. On Jul 17, 2019 this sequence version replaced NM_001426.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGGAAGAAC AGCAGCCGGA ACCTAAAAGT CAGCGCGACT CGGCCCTCGG CGCGGCGGCG 
    GCGGCGACTC CGGGCGGCCT CAGCCTGAGC CTCAGTCCGG GCGCCAGCGG CAGCAGCGGC
    AGCGGCAGCG ATGGAGACAG CGTGCCGGTG TCCCCGCAGC CTGCGCCCCC CTCGCCGCCC
    GCGGCGCCTT GCCTGCCGCC CCTGGCCCAC CACCCGCACC TCCCCCCACA CCCCCCGCCC
    CCGCCGCCTC AGCATCTCGC GGCGCCTGCT CACCAGCCGC AGCCAGCGGC CCAGCTGCAC
    CGCACCACCA ACTTTTTCAT CGACAACATC CTGAGGCCGG ACTTCGGCTG CAAAAAGGAG
    CAGCCGCCAC CGCAGCTTCT GGTGGCTGCG GCGGCCAGAG GAGGCGCAGG AGGAGGAGGC
    CGGGTCGAGC GTGACAGAGG CCAGACTGCC GCAGGTAGAG ACCCTGTCCA CCCGTTGGGC
    ACCCGGGCGC CAGGCGCTGC CTCGCTCCTG TGCGCCCCGG ACGCGAACTG TGGCCCACCC
    GACGGCTCCC AGCCAGCCGC CGCCGGCGCG GGCGCGTCTA AAGCTGGGAA CCCGGCTGCG
    GCGGCGGCGG CGGCCGCGGC GGCAGTGGCG GCGGCGGCGG CGGCCGCAGC AGCCAAGCCC
    TCGGACACCG GTGGCGGCGG CAGTGGAGGC GGCGCGGGGA GCCCCGGAGC GCAGGGCACC
    AAATACCCGG AGCACGGCAA CCCGGCTATC CTACTTATGG GCTCAGCCAA CGGCGGGCCC
    GTGGTCAAAA CTGACTCGCA GCAGCCTCTC GTATGGCCCG CCTGGGTGTA CTGCACACGT
    TATTCGGATC GTCCATCCTC CGGTCCGCGC ACCAGGAAGC TGAAGAAGAA GAAGAACGAG
    AAGGAGGACA AGCGGCCGCG GACCGCGTTC ACGGCCGAGC AGCTGCAGAG ACTCAAGGCG
    GAGTTCCAGG CAAACCGCTA CATCACGGAG CAGCGGCGGC AGACCCTGGC CCAGGAACTC
    AGCCTCAACG AGTCCCAGAT CAAGATCTGG TTCCAGAACA AGCGCGCCAA GATCAAGAAA
    GCCACAGGCA TCAAGAACGG CCTGGCGCTG CACCTCATGG CCCAGGGACT GTACAACCAC
    TCCACCACCA CGGTCCAGGA CAAAGACGAG AGCGAGTAG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001417.3
    CDS482..1660
    Translation

    Target ORF information:

    RefSeq Version NM_001426.4
    Organism Homo sapiens(human)
    Definition Homo sapiens engrailed homeobox 1 (EN1), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001426.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGGAAGAAC AGCAGCCGGA ACCTAAAAGT CAGCGCGACT CGGCCCTCGG CGCGGCGGCG 
    GCGGCGACTC CGGGCGGCCT CAGCCTGAGC CTCAGTCCGG GCGCCAGCGG CAGCAGCGGC
    AGCGGCAGCG ATGGAGACAG CGTGCCGGTG TCCCCGCAGC CTGCGCCCCC CTCGCCGCCC
    GCGGCGCCTT GCCTGCCGCC CCTGGCCCAC CACCCGCACC TCCCCCCACA CCCCCCGCCC
    CCGCCGCCTC AGCATCTCGC GGCGCCTGCT CACCAGCCGC AGCCAGCGGC CCAGCTGCAC
    CGCACCACCA ACTTTTTCAT CGACAACATC CTGAGGCCGG ACTTCGGCTG CAAAAAGGAG
    CAGCCGCCAC CGCAGCTTCT GGTGGCTGCG GCGGCCAGAG GAGGCGCAGG AGGAGGAGGC
    CGGGTCGAGC GTGACAGAGG CCAGACTGCC GCAGGTAGAG ACCCTGTCCA CCCGTTGGGC
    ACCCGGGCGC CAGGCGCTGC CTCGCTCCTG TGCGCCCCGG ACGCGAACTG TGGCCCACCC
    GACGGCTCCC AGCCAGCCGC CGCCGGCGCG GGCGCGTCTA AAGCTGGGAA CCCGGCTGCG
    GCGGCGGCGG CGGCCGCGGC GGCAGTGGCG GCGGCGGCGG CGGCCGCAGC AGCCAAGCCC
    TCGGACACCG GTGGCGGCGG CAGTGGAGGC GGCGCGGGGA GCCCCGGAGC GCAGGGCACC
    AAATACCCGG AGCACGGCAA CCCGGCTATC CTACTTATGG GCTCAGCCAA CGGCGGGCCC
    GTGGTCAAAA CTGACTCGCA GCAGCCTCTC GTATGGCCCG CCTGGGTGTA CTGCACACGT
    TATTCGGATC GTCCATCCTC CGGTCCGCGC ACCAGGAAGC TGAAGAAGAA GAAGAACGAG
    AAGGAGGACA AGCGGCCGCG GACCGCGTTC ACGGCCGAGC AGCTGCAGAG ACTCAAGGCG
    GAGTTCCAGG CAAACCGCTA CATCACGGAG CAGCGGCGGC AGACCCTGGC CCAGGAACTC
    AGCCTCAACG AGTCCCAGAT CAAGATCTGG TTCCAGAACA AGCGCGCCAA GATCAAGAAA
    GCCACAGGCA TCAAGAACGG CCTGGCGCTG CACCTCATGG CCCAGGGACT GTACAACCAC
    TCCACCACCA CGGTCCAGGA CAAAGACGAG AGCGAGTAG

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

  • PubMed

    Engrailed 1 overexpression as a potential prognostic marker in quintuple-negative breast cancer.
    Cancer biology & therapy0(2018 Jan)
    Kim YJ,Sung M,Oh E,Van Vrancken M,Song JY,Jung K,Choi YL


    Association between EN1 rs4144782 and susceptibility of knee osteoarthritis: A case-control study.
    Oncotarget8(22)36650-36657(2017 May)
    Li H,Zhang X,Cao Y,Hu S,Peng F,Zhou J,Li J


    FGFR Inhibitor Ameliorates Hypophosphatemia and Impaired Engrailed-1/Wnt Signaling in FGF2 High Molecular Weight Isoform Transgenic Mice.
    Journal of cellular biochemistry117(9)1991-2000(2016 09)
    Du E,Xiao L,Hurley MM


    Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.
    Nature526(7571)112-7(2015 Oct)
    Zheng HF,Forgetta V,Hsu YH,Estrada K,Rosello-Diez A,Leo PJ,Dahia CL,Park-Min KH,Tobias JH,Kooperberg C,Kleinman A,Styrkarsdottir U,Liu CT,Uggla C,Evans DS,Nielson CM,Walter K,Pettersson-Kymmer U,McCarthy S,Eriksson J,Kwan T,Jhamai M,Trajanoska K,Memari Y,Min J,Huang J,Danecek P,Wilmot B,Li R,Chou WC,Mokry LE,Moayyeri A,Claussnitzer M,Cheng CH,Cheung W,Medina-G?mez C,Ge B,Chen SH,Choi K,Oei L,Fraser J,Kraaij R,Hibbs MA,Gregson CL,Paquette D,Hofman A,Wibom C,Tranah GJ,Marshall M,Gardiner BB,Cremin K,Auer P,Hsu L,Ring S,Tung JY,Thorleifsson G,Enneman AW,van Schoor NM,de Groot LC,van der Velde N,Melin B,Kemp JP,Christiansen C,Sayers A,Zhou Y,Calderari S,van Rooij J,Carlson C,Peters U,Berlivet S,Dostie J,Uitterlinden AG,Williams SR,Farber C,Grinberg D,LaCroix AZ,Haessler J,Chasman DI,Giulianini F,Rose LM,Ridker PM,Eisman JA,Nguyen TV,Center JR,Nogues X,Garcia-Giralt N,Launer LL,Gudnason V,Mellstr?m D,Vandenput L,Amin N,van Duijn CM,Karlsson MK,Ljunggren ?,Svensson O,Hallmans G,Rousseau F,Giroux S,Bussi?re J,Arp PP,Koromani F,Prince RL,Lewis JR,Langdahl BL,Hermann AP,Jensen JE,Kaptoge S,Khaw KT,Reeve J,Formosa MM,Xuereb-Anastasi A,?kesson K,McGuigan FE,Garg G,Olmos JM,Zarrabeitia MT,Riancho JA,Ralston SH,Alonso N,Jiang X,Goltzman D,Pastinen T,Grundberg E,Gauguier D,Orwoll ES,Karasik D,Davey-Smith G,,Smith AV,Siggeirsdottir K,Harris TB,Zillikens MC,van Meurs JB,Thorsteinsdottir U,Maurano MT,Timpson NJ,Soranzo N,Durbin R,Wilson SG,Ntzani EE,Brown MA,Stefansson K,Hinds DA,Spector T,Cupples LA,Ohlsson C,Greenwood CM,,Jackson RD,Rowe DW,Loomis CA,Evans DM,Ackert-Bicknell CL,Joyner AL,Duncan EL,Kiel DP,Rivadeneira F,Richards JB