Gene Symbol | TIGIT |
Entrez Gene ID | 201633 |
Full Name | T cell immunoreceptor with Ig and ITIM domains |
Synonyms | VSIG9,VSTM3,WUCAM |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]. |
Disorder MIM: |