LRRC45 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LRRC45
Entrez Gene ID	201255
Full Name	leucine rich repeat containing 45
General protein information	Preferred Names leucine rich repeat containing 45 Names leucine-rich repeat-containing protein 45
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q25.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_144999.3	NP_659436.1	leucine-rich repeat-containing protein 45
NM_144999.4	NP_659436.1	leucine-rich repeat-containing protein 45

Pathways from BioSystems

Homologies

	LRRC45	XP_001112894.1
Pan troglodytes (chimpanzee)	LRRC45	XP_511754.2
Danio rerio (zebrafish)	si:dkey-202c14.4	XP_002663924.1
Mus musculus (house mouse)	Lrrc45	NP_705773.2
Canis lupus familiaris (dog)	LRRC45	XP_540494.2
Rattus norvegicus (Norway rat)	Lrrc45	NP_001121043.1
Xenopus tropicalis (tropical clawed frog)	lrrc45	NP_001184030.1
Homo sapiens (human)	LRRC45	NP_659436.1
Bos taurus (cattle)	LRRC45	NP_001178207.2
Gallus gallus (chicken)	LRRC45	NP_001073224.1

Gene Ontology
Bibliography

Related articles in PubMed

LRRC45 is a centrosome linker component required for centrosome cohesion.
He R, Huang N, Bao Y, Zhou H, Teng J, Chen J
Cell reports4(6)1100-7(2013 Sep)

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.
Jakobsen L, Vanselow K, Skogs M, Toyoda Y, Lundberg E, Poser I, Falkenby LG, Bennetzen M, Westendorf J, Nigg EA, Uhlen M, Hyman AA, Andersen JS
The EMBO journal30(8)1520-35(2011 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

LRRC45 is a critical component of the proteinaceous linker between two centrioles and is required for centrosome cohesion.
Title: LRRC45 is a centrosome linker component required for centrosome cohesion.

The following LRRC45 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LRRC45 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu06433	NM_144999.4 Latest version!	Homo sapiens leucine rich repeat containing 45 (LRRC45), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
View Old Accession Versions >>
OHu06433	NM_144999.3	Homo sapiens leucine rich repeat containing 45 (LRRC45), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LRRC45 ( NM_144999.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_659436.1 Homo sapiens leucine rich repeat containing 45 (LRRC45), mRNA.

Price & Availability↑

CloneID	OHu06433
Clone ID Related Accession (Same CDS sequence)	NM_144999.3 , NM_144999.4
Accession Version	NM_144999.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2013bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 45
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC137723.6, BI837975.1 and BC014109.2. On Jan 13, 2015 this sequence version replaced NM_144999.2. ##Evidence-Data-START## Transcript exon combination :: BC014109.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGT TCCGGCGCTC CTACAGCCGC CTGTGCAGGG AGAGTGGGGC CGAGCCCCAG 
GAGGCTGTCC TGCAGCAGCT GCACCAGCTT CCCAGGGGCC GGCTGGACCT GGCCACGCAA 
AGCCTGACGG TGGAGACCTG CAGGGCCCTG GGCAAGCTGC TGCCGAGGGA GACGCTGTGC 
ACGGAGCTGG TCCTGAGTGA CTGCATGCTC AGCGAGGAAG GGGCCACACT GCTGCTCCGA 
GGCCTGTGTG CCAACACCGT GCTGCGCTTT CTGGACTTAA AGGGCAACAA CCTTCGGGCT 
GCAGGGGCCG AGGCTCTGGG AAAACTCCTC CAACAGAACA AGTCCATTCA GAGCCTCACG 
CTGGAGTGGA ACAGCCTGGG CACGTGGGAC GATGCCTTCG CCACCTTCTG CGGGGGCCTG 
GCGGCCAACG GCGCCCTGCA GCGGCTGGAC CTCCGCAACA ACCAGATCAG TCACAAGGGC 
GCGGAGGAGC TGGCCCTAGC CCTGAAGGGC AACACCACCC TCCAGCAGCT GGACCTGCGC 
TGGAATAACG TTGGCCTCCT GGGGGGCCGG GCCCTCATGA ACTGTCTCCC CAGCAACAGA 
ACCCTGTGGA GACTGGACCT GGCTGGGAAC AACATCCCTG GAGACGTCCT CAGAGCCGTG 
GAGCAAGCCA TGGGCCACAG CCAGGACCGG CTCACCACCT TCCAGGAGAA CCAAGCCCGC 
ACTCACGTCC TCAGCAAGGA GGTCCAGCAC CTCCGGGAGG AGAAGTCCAA GCAGTTCCTC 
GACTTGATGG AGACTATTGA TAAGCAGCGA GAAGAGATGG CCAAGAGCAG CAGGGCGTCG 
GCAGCCCGTG TAGGGCAGCT TCAGGAAGCC CTGAATGAGA GGCACTCCAT CATCAACGCT 
CTCAAGGCCA AGCTGCAGAT GACAGAGGCC GCCCTGGCTC TGTCGGAGCA GAAGGCCCAG 
GACCTGGGGG AGCTCCTGGC CACAGCGGAG CAGGAGCAGC TGAGCCTGTC ACAGAGGCAG 
GCCAAGGAGC TCAAGCTGGA GCAGCAGGAA GCTGCAGAGC GGGAGTCTAA ACTCCTCAGA 
GACTTGTCTG CTGCCAATGA AAAGAACCTG CTTCTGCAAA ACCAGGTAGA CGAGTTGGAG 
CGGAAGTTCA GGTGTCAGCA GGAGCAGCTG TTCCAGACCA GGCAGGAGAT GACCAGCATG 
TCAGCTGAGC TGAAGATGCG GGCCATCCAG GCCGAGGAGC GCCTGGACAT GGAGAAGAGA 
AGATGCAGAC AGAGCCTGGA GGACTCCGAA AGCCTGCGCA TCAAGGAGGT GGAGCATATG 
ACCCGTCACC TGGAGGAGAG TGAGAAGGCC ATGCAGGAGC GGGTGCAGAG GCTGGAGGCG 
GCGCGGCTGT CCCTGGAGGA GGAGCTGAGC CGAGTGAAAG CAGCGGCACT CAGCGAGCGT 
GGCCAGGCTG AGGAGGAGCT GATCAAGGCC AAGAGCCAGG CCCGCCTGGA GGAGCAACAG 
CGCCTGGCTC ACCTGGAGGA CAAGCTGAGA CTGCTGGCGC AGGCACGGGA CGAGGCGCAG 
GGCGCTTGCC TACAGCAGAA GCAGGTGGTG GCCGAGGCCC AGACCCGGGT CAGCCAGCTG 
GGCCTGCAAG TTGAGGGCCT GCGGCGGCGC CTGGAAGAGC TGCAGCAGGA GCTGAGCCTC 
AAGGACCAGG AAAGGGTGGC CGAGGTGAGC AGGGTGCGCG TGGAGCTGCA GGAGCAGAAC 
GGCCGGCTGC AGGCGGAGCT GGCGGCTCAG GAGGCGCTGA GGGAGAAGGC GGCGGCCCTG 
GAGCGCCAGC TGAAAGTGAT GGCGAGCGAC CACCGAGAGG CGCTGCTGGA CAGGGAGAGC 
GAGAACGCGT CTCTCCGGGA GAAGCTGCGG CTCCGGGAGG CGGAGATCGC CCGCATCCGG 
GACGAGGAGG CCCAGAGGGC GAGCTTCCTG CAGAACGCCG TCCTGGCTTA CGTGCAGGCG 
TCCCCCGTGA GGACCCTGAG CCCCCCAAAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_659436.1
CDS	343..2355
Translation	MEEFRRSYSRLCRESGAEPQEAVLQQLHQLPRGRLDLATQSLTVETCRALGKLLPRETLCTELVLSDCMLSEEGATLLLRGLCANTVLRFLDLKGNNLRAAGAEALGKLLQQNKSIQSLTLEWNSLGTWDDAFATFCGGLAANGALQRLDLRNNQISHKGAEELALALKGNTTLQQLDLRWNNVGLLGGRALMNCLPSNRTLWRLDLAGNNIPGDVLRAVEQAMGHSQDRLTTFQENQARTHVLSKEVQHLREEKSKQFLDLMETIDKQREEMAKSSRASAARVGQLQEALNERHSIINALKAKLQMTEAALALSEQKAQDLGELLATAEQEQLSLSQRQAKELKLEQQEAAERESKLLRDLSAANEKNLLLQNQVDELERKFRCQQEQLFQTRQEMTSMSAELKMRAIQAEERLDMEKRRCRQSLEDSESLRIKEVEHMTRHLEESEKAMQERVQRLEAARLSLEEELSRVKAAALSERGQAEEELIKAKSQARLEEQQRLAHLEDKLRLLAQARDEAQGACLQQKQVVAEAQTRVSQLGLQVEGLRRRLEELQQELSLKDQERVAEVSRVRVELQEQNGRLQAELAAQEALREKAAALERQLKVMASDHREALLDRESENASLREKLRLREAEIARIRDEEAQRASFLQNAVLAYVQASPVRTLSPPK

Target ORF information:

RefSeq Version	NM_144999.3
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 45 (LRRC45), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_144999.3

ORF Insert Sequence:

ATGGAGGAGT TCCGGCGCTC CTACAGCCGC CTGTGCAGGG AGAGTGGGGC CGAGCCCCAG 
GAGGCTGTCC TGCAGCAGCT GCACCAGCTT CCCAGGGGCC GGCTGGACCT GGCCACGCAA 
AGCCTGACGG TGGAGACCTG CAGGGCCCTG GGCAAGCTGC TGCCGAGGGA GACGCTGTGC 
ACGGAGCTGG TCCTGAGTGA CTGCATGCTC AGCGAGGAAG GGGCCACACT GCTGCTCCGA 
GGCCTGTGTG CCAACACCGT GCTGCGCTTT CTGGACTTAA AGGGCAACAA CCTTCGGGCT 
GCAGGGGCCG AGGCTCTGGG AAAACTCCTC CAACAGAACA AGTCCATTCA GAGCCTCACG 
CTGGAGTGGA ACAGCCTGGG CACGTGGGAC GATGCCTTCG CCACCTTCTG CGGGGGCCTG 
GCGGCCAACG GCGCCCTGCA GCGGCTGGAC CTCCGCAACA ACCAGATCAG TCACAAGGGC 
GCGGAGGAGC TGGCCCTAGC CCTGAAGGGC AACACCACCC TCCAGCAGCT GGACCTGCGC 
TGGAATAACG TTGGCCTCCT GGGGGGCCGG GCCCTCATGA ACTGTCTCCC CAGCAACAGA 
ACCCTGTGGA GACTGGACCT GGCTGGGAAC AACATCCCTG GAGACGTCCT CAGAGCCGTG 
GAGCAAGCCA TGGGCCACAG CCAGGACCGG CTCACCACCT TCCAGGAGAA CCAAGCCCGC 
ACTCACGTCC TCAGCAAGGA GGTCCAGCAC CTCCGGGAGG AGAAGTCCAA GCAGTTCCTC 
GACTTGATGG AGACTATTGA TAAGCAGCGA GAAGAGATGG CCAAGAGCAG CAGGGCGTCG 
GCAGCCCGTG TAGGGCAGCT TCAGGAAGCC CTGAATGAGA GGCACTCCAT CATCAACGCT 
CTCAAGGCCA AGCTGCAGAT GACAGAGGCC GCCCTGGCTC TGTCGGAGCA GAAGGCCCAG 
GACCTGGGGG AGCTCCTGGC CACAGCGGAG CAGGAGCAGC TGAGCCTGTC ACAGAGGCAG 
GCCAAGGAGC TCAAGCTGGA GCAGCAGGAA GCTGCAGAGC GGGAGTCTAA ACTCCTCAGA 
GACTTGTCTG CTGCCAATGA AAAGAACCTG CTTCTGCAAA ACCAGGTAGA CGAGTTGGAG 
CGGAAGTTCA GGTGTCAGCA GGAGCAGCTG TTCCAGACCA GGCAGGAGAT GACCAGCATG 
TCAGCTGAGC TGAAGATGCG GGCCATCCAG GCCGAGGAGC GCCTGGACAT GGAGAAGAGA 
AGATGCAGAC AGAGCCTGGA GGACTCCGAA AGCCTGCGCA TCAAGGAGGT GGAGCATATG 
ACCCGTCACC TGGAGGAGAG TGAGAAGGCC ATGCAGGAGC GGGTGCAGAG GCTGGAGGCG 
GCGCGGCTGT CCCTGGAGGA GGAGCTGAGC CGAGTGAAAG CAGCGGCACT CAGCGAGCGT 
GGCCAGGCTG AGGAGGAGCT GATCAAGGCC AAGAGCCAGG CCCGCCTGGA GGAGCAACAG 
CGCCTGGCTC ACCTGGAGGA CAAGCTGAGA CTGCTGGCGC AGGCACGGGA CGAGGCGCAG 
GGCGCTTGCC TACAGCAGAA GCAGGTGGTG GCCGAGGCCC AGACCCGGGT CAGCCAGCTG 
GGCCTGCAAG TTGAGGGCCT GCGGCGGCGC CTGGAAGAGC TGCAGCAGGA GCTGAGCCTC 
AAGGACCAGG AAAGGGTGGC CGAGGTGAGC AGGGTGCGCG TGGAGCTGCA GGAGCAGAAC 
GGCCGGCTGC AGGCGGAGCT GGCGGCTCAG GAGGCGCTGA GGGAGAAGGC GGCGGCCCTG 
GAGCGCCAGC TGAAAGTGAT GGCGAGCGAC CACCGAGAGG CGCTGCTGGA CAGGGAGAGC 
GAGAACGCGT CTCTCCGGGA GAAGCTGCGG CTCCGGGAGG CGGAGATCGC CCGCATCCGG 
GACGAGGAGG CCCAGAGGGC GAGCTTCCTG CAGAACGCCG TCCTGGCTTA CGTGCAGGCG 
TCCCCCGTGA GGACCCTGAG CCCCCCAAAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRC45 ( NM_144999.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_659436.1 Homo sapiens leucine rich repeat containing 45 (LRRC45), mRNA.

Price & Availability↑

CloneID	OHu06433
Clone ID Related Accession (Same CDS sequence)	NM_144999.3 , NM_144999.4
Accession Version	NM_144999.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2013bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	leucine-rich repeat-containing protein 45
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC137723.6, BI837975.1 and BC014109.2. On Nov 23, 2018 this sequence version replaced NM_144999.3. ##Evidence-Data-START## Transcript exon combination :: BC014109.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000306688.8/ ENSP00000306760.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGGAGT TCCGGCGCTC CTACAGCCGC CTGTGCAGGG AGAGTGGGGC CGAGCCCCAG 
GAGGCTGTCC TGCAGCAGCT GCACCAGCTT CCCAGGGGCC GGCTGGACCT GGCCACGCAA 
AGCCTGACGG TGGAGACCTG CAGGGCCCTG GGCAAGCTGC TGCCGAGGGA GACGCTGTGC 
ACGGAGCTGG TCCTGAGTGA CTGCATGCTC AGCGAGGAAG GGGCCACACT GCTGCTCCGA 
GGCCTGTGTG CCAACACCGT GCTGCGCTTT CTGGACTTAA AGGGCAACAA CCTTCGGGCT 
GCAGGGGCCG AGGCTCTGGG AAAACTCCTC CAACAGAACA AGTCCATTCA GAGCCTCACG 
CTGGAGTGGA ACAGCCTGGG CACGTGGGAC GATGCCTTCG CCACCTTCTG CGGGGGCCTG 
GCGGCCAACG GCGCCCTGCA GCGGCTGGAC CTCCGCAACA ACCAGATCAG TCACAAGGGC 
GCGGAGGAGC TGGCCCTAGC CCTGAAGGGC AACACCACCC TCCAGCAGCT GGACCTGCGC 
TGGAATAACG TTGGCCTCCT GGGGGGCCGG GCCCTCATGA ACTGTCTCCC CAGCAACAGA 
ACCCTGTGGA GACTGGACCT GGCTGGGAAC AACATCCCTG GAGACGTCCT CAGAGCCGTG 
GAGCAAGCCA TGGGCCACAG CCAGGACCGG CTCACCACCT TCCAGGAGAA CCAAGCCCGC 
ACTCACGTCC TCAGCAAGGA GGTCCAGCAC CTCCGGGAGG AGAAGTCCAA GCAGTTCCTC 
GACTTGATGG AGACTATTGA TAAGCAGCGA GAAGAGATGG CCAAGAGCAG CAGGGCGTCG 
GCAGCCCGTG TAGGGCAGCT TCAGGAAGCC CTGAATGAGA GGCACTCCAT CATCAACGCT 
CTCAAGGCCA AGCTGCAGAT GACAGAGGCC GCCCTGGCTC TGTCGGAGCA GAAGGCCCAG 
GACCTGGGGG AGCTCCTGGC CACAGCGGAG CAGGAGCAGC TGAGCCTGTC ACAGAGGCAG 
GCCAAGGAGC TCAAGCTGGA GCAGCAGGAA GCTGCAGAGC GGGAGTCTAA ACTCCTCAGA 
GACTTGTCTG CTGCCAATGA AAAGAACCTG CTTCTGCAAA ACCAGGTAGA CGAGTTGGAG 
CGGAAGTTCA GGTGTCAGCA GGAGCAGCTG TTCCAGACCA GGCAGGAGAT GACCAGCATG 
TCAGCTGAGC TGAAGATGCG GGCCATCCAG GCCGAGGAGC GCCTGGACAT GGAGAAGAGA 
AGATGCAGAC AGAGCCTGGA GGACTCCGAA AGCCTGCGCA TCAAGGAGGT GGAGCATATG 
ACCCGTCACC TGGAGGAGAG TGAGAAGGCC ATGCAGGAGC GGGTGCAGAG GCTGGAGGCG 
GCGCGGCTGT CCCTGGAGGA GGAGCTGAGC CGAGTGAAAG CAGCGGCACT CAGCGAGCGT 
GGCCAGGCTG AGGAGGAGCT GATCAAGGCC AAGAGCCAGG CCCGCCTGGA GGAGCAACAG 
CGCCTGGCTC ACCTGGAGGA CAAGCTGAGA CTGCTGGCGC AGGCACGGGA CGAGGCGCAG 
GGCGCTTGCC TACAGCAGAA GCAGGTGGTG GCCGAGGCCC AGACCCGGGT CAGCCAGCTG 
GGCCTGCAAG TTGAGGGCCT GCGGCGGCGC CTGGAAGAGC TGCAGCAGGA GCTGAGCCTC 
AAGGACCAGG AAAGGGTGGC CGAGGTGAGC AGGGTGCGCG TGGAGCTGCA GGAGCAGAAC 
GGCCGGCTGC AGGCGGAGCT GGCGGCTCAG GAGGCGCTGA GGGAGAAGGC GGCGGCCCTG 
GAGCGCCAGC TGAAAGTGAT GGCGAGCGAC CACCGAGAGG CGCTGCTGGA CAGGGAGAGC 
GAGAACGCGT CTCTCCGGGA GAAGCTGCGG CTCCGGGAGG CGGAGATCGC CCGCATCCGG 
GACGAGGAGG CCCAGAGGGC GAGCTTCCTG CAGAACGCCG TCCTGGCTTA CGTGCAGGCG 
TCCCCCGTGA GGACCCTGAG CCCCCCAAAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_659436.1
CDS	340..2352
Translation	MEEFRRSYSRLCRESGAEPQEAVLQQLHQLPRGRLDLATQSLTVETCRALGKLLPRETLCTELVLSDCMLSEEGATLLLRGLCANTVLRFLDLKGNNLRAAGAEALGKLLQQNKSIQSLTLEWNSLGTWDDAFATFCGGLAANGALQRLDLRNNQISHKGAEELALALKGNTTLQQLDLRWNNVGLLGGRALMNCLPSNRTLWRLDLAGNNIPGDVLRAVEQAMGHSQDRLTTFQENQARTHVLSKEVQHLREEKSKQFLDLMETIDKQREEMAKSSRASAARVGQLQEALNERHSIINALKAKLQMTEAALALSEQKAQDLGELLATAEQEQLSLSQRQAKELKLEQQEAAERESKLLRDLSAANEKNLLLQNQVDELERKFRCQQEQLFQTRQEMTSMSAELKMRAIQAEERLDMEKRRCRQSLEDSESLRIKEVEHMTRHLEESEKAMQERVQRLEAARLSLEEELSRVKAAALSERGQAEEELIKAKSQARLEEQQRLAHLEDKLRLLAQARDEAQGACLQQKQVVAEAQTRVSQLGLQVEGLRRRLEELQQELSLKDQERVAEVSRVRVELQEQNGRLQAELAAQEALREKAAALERQLKVMASDHREALLDRESENASLREKLRLREAEIARIRDEEAQRASFLQNAVLAYVQASPVRTLSPPK

Target ORF information:

RefSeq Version	NM_144999.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat containing 45 (LRRC45), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_144999.4

ORF Insert Sequence:

ATGGAGGAGT TCCGGCGCTC CTACAGCCGC CTGTGCAGGG AGAGTGGGGC CGAGCCCCAG 
GAGGCTGTCC TGCAGCAGCT GCACCAGCTT CCCAGGGGCC GGCTGGACCT GGCCACGCAA 
AGCCTGACGG TGGAGACCTG CAGGGCCCTG GGCAAGCTGC TGCCGAGGGA GACGCTGTGC 
ACGGAGCTGG TCCTGAGTGA CTGCATGCTC AGCGAGGAAG GGGCCACACT GCTGCTCCGA 
GGCCTGTGTG CCAACACCGT GCTGCGCTTT CTGGACTTAA AGGGCAACAA CCTTCGGGCT 
GCAGGGGCCG AGGCTCTGGG AAAACTCCTC CAACAGAACA AGTCCATTCA GAGCCTCACG 
CTGGAGTGGA ACAGCCTGGG CACGTGGGAC GATGCCTTCG CCACCTTCTG CGGGGGCCTG 
GCGGCCAACG GCGCCCTGCA GCGGCTGGAC CTCCGCAACA ACCAGATCAG TCACAAGGGC 
GCGGAGGAGC TGGCCCTAGC CCTGAAGGGC AACACCACCC TCCAGCAGCT GGACCTGCGC 
TGGAATAACG TTGGCCTCCT GGGGGGCCGG GCCCTCATGA ACTGTCTCCC CAGCAACAGA 
ACCCTGTGGA GACTGGACCT GGCTGGGAAC AACATCCCTG GAGACGTCCT CAGAGCCGTG 
GAGCAAGCCA TGGGCCACAG CCAGGACCGG CTCACCACCT TCCAGGAGAA CCAAGCCCGC 
ACTCACGTCC TCAGCAAGGA GGTCCAGCAC CTCCGGGAGG AGAAGTCCAA GCAGTTCCTC 
GACTTGATGG AGACTATTGA TAAGCAGCGA GAAGAGATGG CCAAGAGCAG CAGGGCGTCG 
GCAGCCCGTG TAGGGCAGCT TCAGGAAGCC CTGAATGAGA GGCACTCCAT CATCAACGCT 
CTCAAGGCCA AGCTGCAGAT GACAGAGGCC GCCCTGGCTC TGTCGGAGCA GAAGGCCCAG 
GACCTGGGGG AGCTCCTGGC CACAGCGGAG CAGGAGCAGC TGAGCCTGTC ACAGAGGCAG 
GCCAAGGAGC TCAAGCTGGA GCAGCAGGAA GCTGCAGAGC GGGAGTCTAA ACTCCTCAGA 
GACTTGTCTG CTGCCAATGA AAAGAACCTG CTTCTGCAAA ACCAGGTAGA CGAGTTGGAG 
CGGAAGTTCA GGTGTCAGCA GGAGCAGCTG TTCCAGACCA GGCAGGAGAT GACCAGCATG 
TCAGCTGAGC TGAAGATGCG GGCCATCCAG GCCGAGGAGC GCCTGGACAT GGAGAAGAGA 
AGATGCAGAC AGAGCCTGGA GGACTCCGAA AGCCTGCGCA TCAAGGAGGT GGAGCATATG 
ACCCGTCACC TGGAGGAGAG TGAGAAGGCC ATGCAGGAGC GGGTGCAGAG GCTGGAGGCG 
GCGCGGCTGT CCCTGGAGGA GGAGCTGAGC CGAGTGAAAG CAGCGGCACT CAGCGAGCGT 
GGCCAGGCTG AGGAGGAGCT GATCAAGGCC AAGAGCCAGG CCCGCCTGGA GGAGCAACAG 
CGCCTGGCTC ACCTGGAGGA CAAGCTGAGA CTGCTGGCGC AGGCACGGGA CGAGGCGCAG 
GGCGCTTGCC TACAGCAGAA GCAGGTGGTG GCCGAGGCCC AGACCCGGGT CAGCCAGCTG 
GGCCTGCAAG TTGAGGGCCT GCGGCGGCGC CTGGAAGAGC TGCAGCAGGA GCTGAGCCTC 
AAGGACCAGG AAAGGGTGGC CGAGGTGAGC AGGGTGCGCG TGGAGCTGCA GGAGCAGAAC 
GGCCGGCTGC AGGCGGAGCT GGCGGCTCAG GAGGCGCTGA GGGAGAAGGC GGCGGCCCTG 
GAGCGCCAGC TGAAAGTGAT GGCGAGCGAC CACCGAGAGG CGCTGCTGGA CAGGGAGAGC 
GAGAACGCGT CTCTCCGGGA GAAGCTGCGG CTCCGGGAGG CGGAGATCGC CCGCATCCGG 
GACGAGGAGG CCCAGAGGGC GAGCTTCCTG CAGAACGCCG TCCTGGCTTA CGTGCAGGCG 
TCCCCCGTGA GGACCCTGAG CCCCCCAAAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

LRRC45 is a centrosome linker component required for centrosome cohesion.
Cell reports4(6)1100-7(2013 Sep)
He R,Huang N,Bao Y,Zhou H,Teng J,Chen J

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.
The EMBO journal30(8)1520-35(2011 Apr)
Jakobsen L,Vanselow K,Skogs M,Toyoda Y,Lundberg E,Poser I,Falkenby LG,Bennetzen M,Westendorf J,Nigg EA,Uhlen M,Hyman AA,Andersen JS

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LRRC45 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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