HTR3D cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HTR3D
Entrez Gene ID	200909
Full Name	5-hydroxytryptamine receptor 3D
Synonyms	5HT3D
General protein information	Preferred Names 5-hydroxytryptamine receptor 3D Names 5-hydroxytryptamine receptor 3D 5-hydroxytryptamine (serotonin) receptor 3 family member D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic 5-hydroxytryptamine receptor 3 subunit D serotonin 5-HT-3D receptor serotonin receptor 3D
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q27.1
Summary	The protein encoded this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric disorders, including anxiety, depression, and migraine. Serotonin receptors causes fast and depolarizing responses in neurons following activation. The genes encoding subunits C, D and E of this type 3 receptor form a cluster on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009].
Disorder MIM:	610122

mRNA and Protein(s)

mRNA	Protein	Name
NM_001145143.1	NP_001138615.1	5-hydroxytryptamine receptor 3D isoform 1 precursor
XM_017005854.1	XP_016861343.1	5-hydroxytryptamine receptor 3D isoform X1
NM_182537.2	NP_872343.2	5-hydroxytryptamine receptor 3D isoform 2
NM_182537.3	NP_872343.2	5-hydroxytryptamine receptor 3D isoform 2
NM_001163646.1	NP_001157118.1	5-hydroxytryptamine receptor 3D isoform 3 precursor
NM_001163646.2	NP_001157118.1	5-hydroxytryptamine receptor 3D isoform 3 precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Genetic Association of the PARL-ABCC5-HTR3D-HTR3C Locus With Primary Angle-Closure Glaucoma in Chinese.
Tang FY, Ma L, Tam POS, Pang CP, Tham CCY, Chen LJ
Investigative ophthalmology & visual science58(10)4384?4389(2017 08)

ABCC5, a gene that influences the anterior chamber depth, is associated with primary angle closure glaucoma.
Nongpiur ME, Khor CC, Jia H, Cornes BK, Chen LJ, Qiao C, Nair KS, Cheng CY, Xu L, George R, Tan D, Abu-Amero K, Perera SA, Ozaki M, Mizoguchi T, Kurimoto Y, Low S, Tajudin LS, Ho CL, Tham CC, Soto I, Chew PT, Wong HT, Shantha B, Kuroda M, Osman EA, Tang G, Fan S, Meng H, Wang H, Feng B, Yong VH, Ting SM, Li Y, Wang YX, Li Z, Lavanya R, Wu RY, Zheng YF, Su DH, Loon SC, Yong VK, Allingham RR, Hauser MA, Soumittra N, Ramprasad VL, Waseem N, Yaakub A, Chia KS, Kumaramanickavel G, Wong TT, How AC, Chau TN, Simmons CP, Bei JX, Zeng YX, Bhattacharya SS, Zhang M, Tan DT, Teo YY, Al-Obeidan SA, Hon DN, Tai ES, Saw SM, Foster PJ, Vijaya L, Jonas JB, Wong TY, John SW, Pang CP, Vithana EN, Wang N, Aung T
PLoS genetics10(3)e1004089(2014 Mar)

A mega-analysis of genome-wide association studies for major depressive disorder.
, Ripke S, Wray NR, Lewis CM, Hamilton SP, Weissman MM, Breen G, Byrne EM, Blackwood DH, Boomsma DI, Cichon S, Heath AC, Holsboer F, Lucae S, Madden PA, Martin NG, McGuffin P, Muglia P, Noethen MM, Penninx BP, Pergadia ML, Potash JB, Rietschel M, Lin D, M?ller-Myhsok B, Shi J, Steinberg S, Grabe HJ, Lichtenstein P, Magnusson P, Perlis RH, Preisig M, Smoller JW, Stefansson K, Uher R, Kutalik Z, Tansey KE, Teumer A, Viktorin A, Barnes MR, Bettecken T, Binder EB, Breuer R, Castro VM, Churchill SE, Coryell WH, Craddock N, Craig IW, Czamara D, De Geus EJ, Degenhardt F, Farmer AE, Fava M, Frank J, Gainer VS, Gallagher PJ, Gordon SD, Goryachev S, Gross M, Guipponi M, Henders AK, Herms S, Hickie IB, Hoefels S, Hoogendijk W, Hottenga JJ, Iosifescu DV, Ising M, Jones I, Jones L, Jung-Ying T, Knowles JA, Kohane IS, Kohli MA, Korszun A, Landen M, Lawson WB, Lewis G, Macintyre D, Maier W, Mattheisen M, McGrath PJ, McIntosh A, McLean A, Middeldorp CM, Middleton L, Montgomery GM, Murphy SN, Nauck M, Nolen WA, Nyholt DR, O'Donovan M, Oskarsson H, Pedersen N, Scheftner WA, Schulz A, Schulze TG, Shyn SI, Sigurdsson E, Slager SL, Smit JH, Stefansson H, Steffens M, Thorgeirsson T, Tozzi F, Treutlein J, Uhr M, van den Oord EJ, Van Grootheest G, V?lzke H, Weilburg JB, Willemsen G, Zitman FG, Neale B, Daly M, Levinson DF, Sullivan PF
Molecular psychiatry18(4)497-511(2013 Apr)

Serotonin receptor diversity in the human colon: Expression of serotonin type 3 receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E.
Kapeller J, M?ller D, Lasitschka F, Autschbach F, Hovius R, Rappold G, Br?ss M, Gershon MD, Niesler B
The Journal of comparative neurology519(3)420-32(2011 Feb)

Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S,
Diabetes care33(10)2250-3(2010 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings enrich the allelic spectrum of ABCC5 in PACG. We identified no tagging SNP responsible for the association of the whole region.
Title: Genetic Association of the PARL-ABCC5-HTR3D-HTR3C Locus With Primary Angle-Closure Glaucoma in Chinese.

Data show that 5-HT3C, 5-HT3D, and 5-HT3E subunits are coexpressed with 5-HT3A in cell bodies of myenteric neurons, and that 5-HT3A and 5-HT3D were expressed in submucosal plexus of the human large intestine.
Title: Serotonin receptor diversity in the human colon: Expression of serotonin type 3 receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: A candidate gene study of obstructive sleep apnea in European Americans and African Americans.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Polymorphism in HTR3D shows different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy.

The following HTR3D gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HTR3D cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu21083	NM_001163646.2 Latest version!	Homo sapiens 5-hydroxytryptamine receptor 3D (HTR3D), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu21198	NM_182537.3 Latest version!	Homo sapiens 5-hydroxytryptamine receptor 3D (HTR3D), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu21886	NM_001145143.1 Latest version!	Homo sapiens 5-hydroxytryptamine receptor 3D (HTR3D), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$237.30 $339.00
OHu93868	XM_017005854.1 Latest version!	Homo sapiens 5-hydroxytryptamine receptor 3D (HTR3D), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu21198	NM_182537.2	Homo sapiens 5-hydroxytryptamine receptor 3D (HTR3D), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu21083	NM_001163646.1	Homo sapiens 5-hydroxytryptamine receptor 3D (HTR3D), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HTR3D ( NM_001163646.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001157118.1 Homo sapiens 5-hydroxytryptamine receptor 3D (HTR3D), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu21083
Clone ID Related Accession (Same CDS sequence)	NM_001163646.1 , NM_001163646.2
Accession Version	NM_001163646.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1365bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Homo sapiens(human)
Product	5-hydroxytryptamine receptor 3D isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ437318.1, AC068644.15, AC131235.4 and AY159812.2. Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ437318.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGAAAC ACTCTCCAGG CCCCCCAGCC CTGGCCCTCC TCTCTCAGTC TCTGCTCACT 
ACAGGAAATG GCGACACTTT GATTATCAAT TGCCCAGGCT TTGGCCAGCA CAGGGTGGAC 
CCTGCAGCCT TTCAAGCAGT GTTTGACAGA AAGGCTATTG GTCCAGTCAC CAACTACAGT 
GTCGCCACTC ATGTCAACAT CTCCTTCACC TTGTCTGCCA TCTGGAACTG CTATTCCAGG 
ATTCACACCT TCAACTGCCA CCATGCCCGG CCTTGGCACA ATCAATTTGT GCAGTGGAAC 
CCAGATGAAT GCGGAGGCAT CAAGAAGTCC GGCATGGCAA CTGAGAACCT ATGGCTTTCA 
GATGTCTTCA TCGAGGAGTC TGTGGATCAG ACACCTGCAG GTCTCATGGC TAGTATGTCA 
ATAGTGAAGG CCACATCAAA CACAATAAGC CAATGTGGGT GGTCAGCATC TGCAAACTGG 
ACACCTTCTA TTTCCCCTTC CATGGACAGA GCCCGGGCAT GGAGAAGGAT GTCCAGGAGC 
TTTCAAATAC ATCACAGAAC CTCATTCAGA ACAAGGAGGG AGTGGGTACT GCTGGGTATC 
CAAAAAAGAA CAATAAAGGT GACCGTGGCC ACTAACCAGT ATGAACAAGC CATCTTCCAT 
GTGGCCATCA GGCGCAGGTG CAGGCCCAGC CCCTACGTGG TAAACTTTCT GGTGCCCAGT 
GGCATTCTGA TTGCCATCGA TGCCCTCAGT TTCTACCTGC CACTGGAAAG TGGGAATTGT 
GCCCCATTCA AGATGACTGT TCTGCTGGGC TACAGCGTCT TCCTGCTCAT GATGAATGAC 
TTGCTCCCAG CCACTAGCAC TTCATCACAT GCTTCACTAG TGGCGCCTCT GGCCCTCATG 
CAGACCCCCT TGCCTGCAGG TGTCTACTTC GCCCTGTGCC TGTCCCTGAT GGTGGGCAGC 
CTGCTGGAGA CCATCTTCAT CACCCACCTG CTGCACGTGG CCACCACCCA GCCCCTACCT 
CTGCCTCGGT GGCTCCACTC CCTGCTGCTG CACTGCACCG GCCAAGGGAG ATGCTGTCCC 
ACTGCGCCCC AGAAGGGAAA TAAGGGCCCG GGTCTCACCC CCACCCACCT GCCCGGTGTG 
AAGGAGCCAG AGGTATCAGC AGGGCAGATG CCAGGCCCTG GGGAGGCAGA GCTGACAGGG 
GGCTCAGAAT GGACAAGGGC CCAGCGGGAA CACGAGGCCC AGAAGCAGCA CTCGGTGGAG 
CTGTGGGTGC AGTTCAGCCA CGCGATGGAC GCCCTGCTCT TCCGCCTCTA CCTGCTCTTC 
ATGGCCTCCT CCATCATCAC CGTCATATGC CTCTGGAACA CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001157118.1
CDS	1..1365
Translation	MQKHSPGPPALALLSQSLLTTGNGDTLIINCPGFGQHRVDPAAFQAVFDRKAIGPVTNYSVATHVNISFTLSAIWNCYSRIHTFNCHHARPWHNQFVQWNPDECGGIKKSGMATENLWLSDVFIEESVDQTPAGLMASMSIVKATSNTISQCGWSASANWTPSISPSMDRARAWRRMSRSFQIHHRTSFRTRREWVLLGIQKRTIKVTVATNQYEQAIFHVAIRRRCRPSPYVVNFLVPSGILIAIDALSFYLPLESGNCAPFKMTVLLGYSVFLLMMNDLLPATSTSSHASLVAPLALMQTPLPAGVYFALCLSLMVGSLLETIFITHLLHVATTQPLPLPRWLHSLLLHCTGQGRCCPTAPQKGNKGPGLTPTHLPGVKEPEVSAGQMPGPGEAELTGGSEWTRAQREHEAQKQHSVELWVQFSHAMDALLFRLYLLFMASSIITVICLWNT

Target ORF information:

RefSeq Version	NM_001163646.1
Organism	Homo sapiens(human)
Definition	Homo sapiens 5-hydroxytryptamine receptor 3D (HTR3D), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001163646.1

ORF Insert Sequence:

ATGCAGAAAC ACTCTCCAGG CCCCCCAGCC CTGGCCCTCC TCTCTCAGTC TCTGCTCACT 
ACAGGAAATG GCGACACTTT GATTATCAAT TGCCCAGGCT TTGGCCAGCA CAGGGTGGAC 
CCTGCAGCCT TTCAAGCAGT GTTTGACAGA AAGGCTATTG GTCCAGTCAC CAACTACAGT 
GTCGCCACTC ATGTCAACAT CTCCTTCACC TTGTCTGCCA TCTGGAACTG CTATTCCAGG 
ATTCACACCT TCAACTGCCA CCATGCCCGG CCTTGGCACA ATCAATTTGT GCAGTGGAAC 
CCAGATGAAT GCGGAGGCAT CAAGAAGTCC GGCATGGCAA CTGAGAACCT ATGGCTTTCA 
GATGTCTTCA TCGAGGAGTC TGTGGATCAG ACACCTGCAG GTCTCATGGC TAGTATGTCA 
ATAGTGAAGG CCACATCAAA CACAATAAGC CAATGTGGGT GGTCAGCATC TGCAAACTGG 
ACACCTTCTA TTTCCCCTTC CATGGACAGA GCCCGGGCAT GGAGAAGGAT GTCCAGGAGC 
TTTCAAATAC ATCACAGAAC CTCATTCAGA ACAAGGAGGG AGTGGGTACT GCTGGGTATC 
CAAAAAAGAA CAATAAAGGT GACCGTGGCC ACTAACCAGT ATGAACAAGC CATCTTCCAT 
GTGGCCATCA GGCGCAGGTG CAGGCCCAGC CCCTACGTGG TAAACTTTCT GGTGCCCAGT 
GGCATTCTGA TTGCCATCGA TGCCCTCAGT TTCTACCTGC CACTGGAAAG TGGGAATTGT 
GCCCCATTCA AGATGACTGT TCTGCTGGGC TACAGCGTCT TCCTGCTCAT GATGAATGAC 
TTGCTCCCAG CCACTAGCAC TTCATCACAT GCTTCACTAG TGGCGCCTCT GGCCCTCATG 
CAGACCCCCT TGCCTGCAGG TGTCTACTTC GCCCTGTGCC TGTCCCTGAT GGTGGGCAGC 
CTGCTGGAGA CCATCTTCAT CACCCACCTG CTGCACGTGG CCACCACCCA GCCCCTACCT 
CTGCCTCGGT GGCTCCACTC CCTGCTGCTG CACTGCACCG GCCAAGGGAG ATGCTGTCCC 
ACTGCGCCCC AGAAGGGAAA TAAGGGCCCG GGTCTCACCC CCACCCACCT GCCCGGTGTG 
AAGGAGCCAG AGGTATCAGC AGGGCAGATG CCAGGCCCTG GGGAGGCAGA GCTGACAGGG 
GGCTCAGAAT GGACAAGGGC CCAGCGGGAA CACGAGGCCC AGAAGCAGCA CTCGGTGGAG 
CTGTGGGTGC AGTTCAGCCA CGCGATGGAC GCCCTGCTCT TCCGCCTCTA CCTGCTCTTC 
ATGGCCTCCT CCATCATCAC CGTCATATGC CTCTGGAACA CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HTR3D ( NM_001163646.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001157118.1 Homo sapiens 5-hydroxytryptamine receptor 3D (HTR3D), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu21083
Clone ID Related Accession (Same CDS sequence)	NM_001163646.1 , NM_001163646.2
Accession Version	NM_001163646.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1365bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	5-hydroxytryptamine receptor 3D isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ437318.1, AC068644.15, AC131235.4 and AY159812.2. On May 31, 2019 this sequence version replaced NM_001163646.1. Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ437318.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGAAAC ACTCTCCAGG CCCCCCAGCC CTGGCCCTCC TCTCTCAGTC TCTGCTCACT 
ACAGGAAATG GCGACACTTT GATTATCAAT TGCCCAGGCT TTGGCCAGCA CAGGGTGGAC 
CCTGCAGCCT TTCAAGCAGT GTTTGACAGA AAGGCTATTG GTCCAGTCAC CAACTACAGT 
GTCGCCACTC ATGTCAACAT CTCCTTCACC TTGTCTGCCA TCTGGAACTG CTATTCCAGG 
ATTCACACCT TCAACTGCCA CCATGCCCGG CCTTGGCACA ATCAATTTGT GCAGTGGAAC 
CCAGATGAAT GCGGAGGCAT CAAGAAGTCC GGCATGGCAA CTGAGAACCT ATGGCTTTCA 
GATGTCTTCA TCGAGGAGTC TGTGGATCAG ACACCTGCAG GTCTCATGGC TAGTATGTCA 
ATAGTGAAGG CCACATCAAA CACAATAAGC CAATGTGGGT GGTCAGCATC TGCAAACTGG 
ACACCTTCTA TTTCCCCTTC CATGGACAGA GCCCGGGCAT GGAGAAGGAT GTCCAGGAGC 
TTTCAAATAC ATCACAGAAC CTCATTCAGA ACAAGGAGGG AGTGGGTACT GCTGGGTATC 
CAAAAAAGAA CAATAAAGGT GACCGTGGCC ACTAACCAGT ATGAACAAGC CATCTTCCAT 
GTGGCCATCA GGCGCAGGTG CAGGCCCAGC CCCTACGTGG TAAACTTTCT GGTGCCCAGT 
GGCATTCTGA TTGCCATCGA TGCCCTCAGT TTCTACCTGC CACTGGAAAG TGGGAATTGT 
GCCCCATTCA AGATGACTGT TCTGCTGGGC TACAGCGTCT TCCTGCTCAT GATGAATGAC 
TTGCTCCCAG CCACTAGCAC TTCATCACAT GCTTCACTAG TGGCGCCTCT GGCCCTCATG 
CAGACCCCCT TGCCTGCAGG TGTCTACTTC GCCCTGTGCC TGTCCCTGAT GGTGGGCAGC 
CTGCTGGAGA CCATCTTCAT CACCCACCTG CTGCACGTGG CCACCACCCA GCCCCTACCT 
CTGCCTCGGT GGCTCCACTC CCTGCTGCTG CACTGCACCG GCCAAGGGAG ATGCTGTCCC 
ACTGCGCCCC AGAAGGGAAA TAAGGGCCCG GGTCTCACCC CCACCCACCT GCCCGGTGTG 
AAGGAGCCAG AGGTATCAGC AGGGCAGATG CCAGGCCCTG GGGAGGCAGA GCTGACAGGG 
GGCTCAGAAT GGACAAGGGC CCAGCGGGAA CACGAGGCCC AGAAGCAGCA CTCGGTGGAG 
CTGTGGGTGC AGTTCAGCCA CGCGATGGAC GCCCTGCTCT TCCGCCTCTA CCTGCTCTTC 
ATGGCCTCCT CCATCATCAC CGTCATATGC CTCTGGAACA CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001157118.1
CDS	1..1365
Translation	MQKHSPGPPALALLSQSLLTTGNGDTLIINCPGFGQHRVDPAAFQAVFDRKAIGPVTNYSVATHVNISFTLSAIWNCYSRIHTFNCHHARPWHNQFVQWNPDECGGIKKSGMATENLWLSDVFIEESVDQTPAGLMASMSIVKATSNTISQCGWSASANWTPSISPSMDRARAWRRMSRSFQIHHRTSFRTRREWVLLGIQKRTIKVTVATNQYEQAIFHVAIRRRCRPSPYVVNFLVPSGILIAIDALSFYLPLESGNCAPFKMTVLLGYSVFLLMMNDLLPATSTSSHASLVAPLALMQTPLPAGVYFALCLSLMVGSLLETIFITHLLHVATTQPLPLPRWLHSLLLHCTGQGRCCPTAPQKGNKGPGLTPTHLPGVKEPEVSAGQMPGPGEAELTGGSEWTRAQREHEAQKQHSVELWVQFSHAMDALLFRLYLLFMASSIITVICLWNT

Target ORF information:

RefSeq Version	NM_001163646.2
Organism	Homo sapiens(human)
Definition	Homo sapiens 5-hydroxytryptamine receptor 3D (HTR3D), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001163646.2

ORF Insert Sequence:

ATGCAGAAAC ACTCTCCAGG CCCCCCAGCC CTGGCCCTCC TCTCTCAGTC TCTGCTCACT 
ACAGGAAATG GCGACACTTT GATTATCAAT TGCCCAGGCT TTGGCCAGCA CAGGGTGGAC 
CCTGCAGCCT TTCAAGCAGT GTTTGACAGA AAGGCTATTG GTCCAGTCAC CAACTACAGT 
GTCGCCACTC ATGTCAACAT CTCCTTCACC TTGTCTGCCA TCTGGAACTG CTATTCCAGG 
ATTCACACCT TCAACTGCCA CCATGCCCGG CCTTGGCACA ATCAATTTGT GCAGTGGAAC 
CCAGATGAAT GCGGAGGCAT CAAGAAGTCC GGCATGGCAA CTGAGAACCT ATGGCTTTCA 
GATGTCTTCA TCGAGGAGTC TGTGGATCAG ACACCTGCAG GTCTCATGGC TAGTATGTCA 
ATAGTGAAGG CCACATCAAA CACAATAAGC CAATGTGGGT GGTCAGCATC TGCAAACTGG 
ACACCTTCTA TTTCCCCTTC CATGGACAGA GCCCGGGCAT GGAGAAGGAT GTCCAGGAGC 
TTTCAAATAC ATCACAGAAC CTCATTCAGA ACAAGGAGGG AGTGGGTACT GCTGGGTATC 
CAAAAAAGAA CAATAAAGGT GACCGTGGCC ACTAACCAGT ATGAACAAGC CATCTTCCAT 
GTGGCCATCA GGCGCAGGTG CAGGCCCAGC CCCTACGTGG TAAACTTTCT GGTGCCCAGT 
GGCATTCTGA TTGCCATCGA TGCCCTCAGT TTCTACCTGC CACTGGAAAG TGGGAATTGT 
GCCCCATTCA AGATGACTGT TCTGCTGGGC TACAGCGTCT TCCTGCTCAT GATGAATGAC 
TTGCTCCCAG CCACTAGCAC TTCATCACAT GCTTCACTAG TGGCGCCTCT GGCCCTCATG 
CAGACCCCCT TGCCTGCAGG TGTCTACTTC GCCCTGTGCC TGTCCCTGAT GGTGGGCAGC 
CTGCTGGAGA CCATCTTCAT CACCCACCTG CTGCACGTGG CCACCACCCA GCCCCTACCT 
CTGCCTCGGT GGCTCCACTC CCTGCTGCTG CACTGCACCG GCCAAGGGAG ATGCTGTCCC 
ACTGCGCCCC AGAAGGGAAA TAAGGGCCCG GGTCTCACCC CCACCCACCT GCCCGGTGTG 
AAGGAGCCAG AGGTATCAGC AGGGCAGATG CCAGGCCCTG GGGAGGCAGA GCTGACAGGG 
GGCTCAGAAT GGACAAGGGC CCAGCGGGAA CACGAGGCCC AGAAGCAGCA CTCGGTGGAG 
CTGTGGGTGC AGTTCAGCCA CGCGATGGAC GCCCTGCTCT TCCGCCTCTA CCTGCTCTTC 
ATGGCCTCCT CCATCATCAC CGTCATATGC CTCTGGAACA CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HTR3D ( NM_182537.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_872343.2 Homo sapiens 5-hydroxytryptamine receptor 3D (HTR3D), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu21198
Clone ID Related Accession (Same CDS sequence)	NM_182537.2 , NM_182537.3
Accession Version	NM_182537.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 840bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-15
Organism	Homo sapiens(human)
Product	5-hydroxytryptamine receptor 3D isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY159812.2, BK001746.1, AC068644.15 and AC131235.4. This sequence is a reference standard in the RefSeqGene project. On May 19, 2004 this sequence version replaced NM_182537.1. Transcript Variant: This variant (2) differs in the presence and absence of exons at its 5' end, and uses a downstream translational start codon, compared to variant 3. The resulting isoform (2) is shorter at the N-terminus, compared to isoform 3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY159812.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2159931 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTAGTA TGTCAATAGT GAAGGCCACA TCAAACACAA TAAGCCAATG TGGGTGGTCA 
GCATCTGCAA ACTGGACACC TTCTATTTCC CCTTCCATGG ACAGAGGTGA ACGCTCTCCT 
TCAGCCCTTT CACCTACACA GGTGGCCATC AGGCGCAGGT GCAGGCCCAG CCCCTACGTG 
GTAAACTTTC TGGTGCCCAG TGGCATTCTG ATTGCCATCG ATGCCCTCAG TTTCTACCTG 
CCACTGGAAA GTGGGAATTG TGCCCCATTC AAGATGACTG TTCTGCTGGG CTACAGCGTC 
TTCCTGCTCA TGATGAATGA CTTGCTCCCA GCCACTAGCA CTTCATCACA TGCTTCACTA 
GTACGTCCTC ATCCATCAAG AGACCAAAAG CGAGGTGTCT ACTTCGCCCT GTGCCTGTCC 
CTGATGGTGG GCAGCCTGCT GGAGACCATC TTCATCACCC ACCTGCTGCA CGTGGCCACC 
ACCCAGCCCC TACCTCTGCC TCGGTGGCTC CACTCCCTGC TGCTGCACTG CACCGGCCAA 
GGGAGATGCT GTCCCACTGC GCCCCAGAAG GGAAATAAGG GCCCGGGTCT CACCCCCACC 
CACCTGCCCG GTGTGAAGGA GCCAGAGGTA TCAGCAGGGC AGATGCCAGG CCCTGGGGAG 
GCAGAGCTGA CAGGGGGCTC AGAATGGACA AGGGCCCAGC GGGAACACGA GGCCCAGAAG 
CAGCACTCGG TGGAGCTGTG GGTGCAGTTC AGCCACGCGA TGGACGCCCT GCTCTTCCGC 
CTCTACCTGC TCTTCATGGC CTCCTCCATC ATCACCGTCA TATGCCTCTG GAACACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_872343.2
CDS	226..1065
Translation	MASMSIVKATSNTISQCGWSASANWTPSISPSMDRGERSPSALSPTQVAIRRRCRPSPYVVNFLVPSGILIAIDALSFYLPLESGNCAPFKMTVLLGYSVFLLMMNDLLPATSTSSHASLVRPHPSRDQKRGVYFALCLSLMVGSLLETIFITHLLHVATTQPLPLPRWLHSLLLHCTGQGRCCPTAPQKGNKGPGLTPTHLPGVKEPEVSAGQMPGPGEAELTGGSEWTRAQREHEAQKQHSVELWVQFSHAMDALLFRLYLLFMASSIITVICLWNT

Target ORF information:

RefSeq Version	NM_182537.2
Organism	Homo sapiens(human)
Definition	Homo sapiens 5-hydroxytryptamine receptor 3D (HTR3D), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182537.2

ORF Insert Sequence:

ATGGCTAGTA TGTCAATAGT GAAGGCCACA TCAAACACAA TAAGCCAATG TGGGTGGTCA 
GCATCTGCAA ACTGGACACC TTCTATTTCC CCTTCCATGG ACAGAGGTGA ACGCTCTCCT 
TCAGCCCTTT CACCTACACA GGTGGCCATC AGGCGCAGGT GCAGGCCCAG CCCCTACGTG 
GTAAACTTTC TGGTGCCCAG TGGCATTCTG ATTGCCATCG ATGCCCTCAG TTTCTACCTG 
CCACTGGAAA GTGGGAATTG TGCCCCATTC AAGATGACTG TTCTGCTGGG CTACAGCGTC 
TTCCTGCTCA TGATGAATGA CTTGCTCCCA GCCACTAGCA CTTCATCACA TGCTTCACTA 
GTACGTCCTC ATCCATCAAG AGACCAAAAG CGAGGTGTCT ACTTCGCCCT GTGCCTGTCC 
CTGATGGTGG GCAGCCTGCT GGAGACCATC TTCATCACCC ACCTGCTGCA CGTGGCCACC 
ACCCAGCCCC TACCTCTGCC TCGGTGGCTC CACTCCCTGC TGCTGCACTG CACCGGCCAA 
GGGAGATGCT GTCCCACTGC GCCCCAGAAG GGAAATAAGG GCCCGGGTCT CACCCCCACC 
CACCTGCCCG GTGTGAAGGA GCCAGAGGTA TCAGCAGGGC AGATGCCAGG CCCTGGGGAG 
GCAGAGCTGA CAGGGGGCTC AGAATGGACA AGGGCCCAGC GGGAACACGA GGCCCAGAAG 
CAGCACTCGG TGGAGCTGTG GGTGCAGTTC AGCCACGCGA TGGACGCCCT GCTCTTCCGC 
CTCTACCTGC TCTTCATGGC CTCCTCCATC ATCACCGTCA TATGCCTCTG GAACACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HTR3D ( NM_182537.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_872343.2 Homo sapiens 5-hydroxytryptamine receptor 3D (HTR3D), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu21198
Clone ID Related Accession (Same CDS sequence)	NM_182537.2 , NM_182537.3
Accession Version	NM_182537.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 840bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	5-hydroxytryptamine receptor 3D isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY159812.2, BK001746.1, AC068644.15 and AC131235.4. This sequence is a reference standard in the RefSeqGene project. On May 31, 2019 this sequence version replaced NM_182537.2. Transcript Variant: This variant (2) differs in the presence and absence of exons at its 5' end, and uses a downstream translational start codon, compared to variant 3. The resulting isoform (2) is shorter at the N-terminus, compared to isoform 3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY159812.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2159931 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTAGTA TGTCAATAGT GAAGGCCACA TCAAACACAA TAAGCCAATG TGGGTGGTCA 
GCATCTGCAA ACTGGACACC TTCTATTTCC CCTTCCATGG ACAGAGGTGA ACGCTCTCCT 
TCAGCCCTTT CACCTACACA GGTGGCCATC AGGCGCAGGT GCAGGCCCAG CCCCTACGTG 
GTAAACTTTC TGGTGCCCAG TGGCATTCTG ATTGCCATCG ATGCCCTCAG TTTCTACCTG 
CCACTGGAAA GTGGGAATTG TGCCCCATTC AAGATGACTG TTCTGCTGGG CTACAGCGTC 
TTCCTGCTCA TGATGAATGA CTTGCTCCCA GCCACTAGCA CTTCATCACA TGCTTCACTA 
GTACGTCCTC ATCCATCAAG AGACCAAAAG CGAGGTGTCT ACTTCGCCCT GTGCCTGTCC 
CTGATGGTGG GCAGCCTGCT GGAGACCATC TTCATCACCC ACCTGCTGCA CGTGGCCACC 
ACCCAGCCCC TACCTCTGCC TCGGTGGCTC CACTCCCTGC TGCTGCACTG CACCGGCCAA 
GGGAGATGCT GTCCCACTGC GCCCCAGAAG GGAAATAAGG GCCCGGGTCT CACCCCCACC 
CACCTGCCCG GTGTGAAGGA GCCAGAGGTA TCAGCAGGGC AGATGCCAGG CCCTGGGGAG 
GCAGAGCTGA CAGGGGGCTC AGAATGGACA AGGGCCCAGC GGGAACACGA GGCCCAGAAG 
CAGCACTCGG TGGAGCTGTG GGTGCAGTTC AGCCACGCGA TGGACGCCCT GCTCTTCCGC 
CTCTACCTGC TCTTCATGGC CTCCTCCATC ATCACCGTCA TATGCCTCTG GAACACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_872343.2
CDS	226..1065
Translation	MASMSIVKATSNTISQCGWSASANWTPSISPSMDRGERSPSALSPTQVAIRRRCRPSPYVVNFLVPSGILIAIDALSFYLPLESGNCAPFKMTVLLGYSVFLLMMNDLLPATSTSSHASLVRPHPSRDQKRGVYFALCLSLMVGSLLETIFITHLLHVATTQPLPLPRWLHSLLLHCTGQGRCCPTAPQKGNKGPGLTPTHLPGVKEPEVSAGQMPGPGEAELTGGSEWTRAQREHEAQKQHSVELWVQFSHAMDALLFRLYLLFMASSIITVICLWNT

Target ORF information:

RefSeq Version	NM_182537.3
Organism	Homo sapiens(human)
Definition	Homo sapiens 5-hydroxytryptamine receptor 3D (HTR3D), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182537.3

ORF Insert Sequence:

ATGGCTAGTA TGTCAATAGT GAAGGCCACA TCAAACACAA TAAGCCAATG TGGGTGGTCA 
GCATCTGCAA ACTGGACACC TTCTATTTCC CCTTCCATGG ACAGAGGTGA ACGCTCTCCT 
TCAGCCCTTT CACCTACACA GGTGGCCATC AGGCGCAGGT GCAGGCCCAG CCCCTACGTG 
GTAAACTTTC TGGTGCCCAG TGGCATTCTG ATTGCCATCG ATGCCCTCAG TTTCTACCTG 
CCACTGGAAA GTGGGAATTG TGCCCCATTC AAGATGACTG TTCTGCTGGG CTACAGCGTC 
TTCCTGCTCA TGATGAATGA CTTGCTCCCA GCCACTAGCA CTTCATCACA TGCTTCACTA 
GTACGTCCTC ATCCATCAAG AGACCAAAAG CGAGGTGTCT ACTTCGCCCT GTGCCTGTCC 
CTGATGGTGG GCAGCCTGCT GGAGACCATC TTCATCACCC ACCTGCTGCA CGTGGCCACC 
ACCCAGCCCC TACCTCTGCC TCGGTGGCTC CACTCCCTGC TGCTGCACTG CACCGGCCAA 
GGGAGATGCT GTCCCACTGC GCCCCAGAAG GGAAATAAGG GCCCGGGTCT CACCCCCACC 
CACCTGCCCG GTGTGAAGGA GCCAGAGGTA TCAGCAGGGC AGATGCCAGG CCCTGGGGAG 
GCAGAGCTGA CAGGGGGCTC AGAATGGACA AGGGCCCAGC GGGAACACGA GGCCCAGAAG 
CAGCACTCGG TGGAGCTGTG GGTGCAGTTC AGCCACGCGA TGGACGCCCT GCTCTTCCGC 
CTCTACCTGC TCTTCATGGC CTCCTCCATC ATCACCGTCA TATGCCTCTG GAACACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HTR3D ( NM_001145143.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138615.1 Homo sapiens 5-hydroxytryptamine receptor 3D (HTR3D), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21886
Clone ID Related Accession (Same CDS sequence)	NM_001145143.1
Accession Version	NM_001145143.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1215bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Homo sapiens(human)
Product	5-hydroxytryptamine receptor 3D isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BK001746.1, AC068644.15 and AC131235.4. Transcript Variant: This variant (1) differs in the 5' coding region, compared to variant 3, resulting in an isoform (1) that is shorter than isoform 3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BK001746.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000428798.7/ ENSP00000405409.2 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAAAGAG GCTGGTTCCA TGGGAAAGGA TTCCTCCTTG GCTTCATCCT CCACCTGCTG 
CTGCAAGATT CACACCTTCA ACTGGTGACA TCGTTCCTGT GGCTAAATAT GTGGAACCCA 
GATGAATGCG GAGGCATCAA GAAGTCCGGC ATGGCAACTG AGAACCTATG GCTTTCAGAT 
GTCTTCATCG AGGAGTCTGT GGATCAGACA CCTGCAGGTC TCATGGCTAG TATGTCAATA 
GTGAAGGCCA CATCAAACAC AATAAGCCAA TGTGGGTGGT CAGCATCTGC AAACTGGACA 
CCTTCTATTT CCCCTTCCAT GGACAGAGGT GAACGCTCTC CTTCAGCCCT TTCACCTACA 
CAGGTAACCC GGGCATGGAG AAGGATGTCC AGGAGCTTTC AAATACATCA CAGAACCTCA 
TTCAGAACAA GGAGGGAGTG GGTACTGCTG GGTATCCAAA AAAGAACAAT AAAGGTGACC 
GTGGCCACTA ACCAGTATGA ACAAGCCATC TTCCATGTGG CCATCAGGCG CAGGTGCAGG 
CCCAGCCCCT ACGTGGTAAA CTTTCTGGTG CCCAGTGGCA TTCTGATTGC CATCGATGCC 
CTCAGTTTCT ACCTGCCACT GGAAAGTGGG AATTGTGCCC CATTCAAGAT GACTGTTCTG 
CTGGGCTACA GCGTCTTCCT GCTCATGATG AATGACTTGC TCCCAGCCAC TAGCACTTCA 
TCACATGCTT CACTAGTACG TCCTCATCCA TCAAGAGACC AAAAGCGAGG TGTCTACTTC 
GCCCTGTGCC TGTCCCTGAT GGTGGGCAGC CTGCTGGAGA CCATCTTCAT CACCCACCTG 
CTGCACGTGG CCACCACCCA GCCCCTACCT CTGCCTCGGT GGCTCCACTC CCTGCTGCTG 
CACTGCACCG GCCAAGGGAG ATGCTGTCCC ACTGCGCCCC AGAAGGGAAA TAAGGGCCCG 
GGTCTCACCC CCACCCACCT GCCCGGTGTG AAGGAGCCAG AGGTATCAGC AGGGCAGATG 
CCAGGCCCTG GGGAGGCAGA GCTGACAGGG GGCTCAGAAT GGACAAGGGC CCAGCGGGAA 
CACGAGGCCC AGAAGCAGCA CTCGGTGGAG CTGTGGGTGC AGTTCAGCCA CGCGATGGAC 
GCCCTGCTCT TCCGCCTCTA CCTGCTCTTC ATGGCCTCCT CCATCATCAC CGTCATATGC 
CTCTGGAACA CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138615.1
CDS	1..1215
Translation	MERGWFHGKGFLLGFILHLLLQDSHLQLVTSFLWLNMWNPDECGGIKKSGMATENLWLSDVFIEESVDQTPAGLMASMSIVKATSNTISQCGWSASANWTPSISPSMDRGERSPSALSPTQVTRAWRRMSRSFQIHHRTSFRTRREWVLLGIQKRTIKVTVATNQYEQAIFHVAIRRRCRPSPYVVNFLVPSGILIAIDALSFYLPLESGNCAPFKMTVLLGYSVFLLMMNDLLPATSTSSHASLVRPHPSRDQKRGVYFALCLSLMVGSLLETIFITHLLHVATTQPLPLPRWLHSLLLHCTGQGRCCPTAPQKGNKGPGLTPTHLPGVKEPEVSAGQMPGPGEAELTGGSEWTRAQREHEAQKQHSVELWVQFSHAMDALLFRLYLLFMASSIITVICLWNT

Target ORF information:

RefSeq Version	NM_001145143.1
Organism	Homo sapiens(human)
Definition	Homo sapiens 5-hydroxytryptamine receptor 3D (HTR3D), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001145143.1

ORF Insert Sequence:

ATGGAAAGAG GCTGGTTCCA TGGGAAAGGA TTCCTCCTTG GCTTCATCCT CCACCTGCTG 
CTGCAAGATT CACACCTTCA ACTGGTGACA TCGTTCCTGT GGCTAAATAT GTGGAACCCA 
GATGAATGCG GAGGCATCAA GAAGTCCGGC ATGGCAACTG AGAACCTATG GCTTTCAGAT 
GTCTTCATCG AGGAGTCTGT GGATCAGACA CCTGCAGGTC TCATGGCTAG TATGTCAATA 
GTGAAGGCCA CATCAAACAC AATAAGCCAA TGTGGGTGGT CAGCATCTGC AAACTGGACA 
CCTTCTATTT CCCCTTCCAT GGACAGAGGT GAACGCTCTC CTTCAGCCCT TTCACCTACA 
CAGGTAACCC GGGCATGGAG AAGGATGTCC AGGAGCTTTC AAATACATCA CAGAACCTCA 
TTCAGAACAA GGAGGGAGTG GGTACTGCTG GGTATCCAAA AAAGAACAAT AAAGGTGACC 
GTGGCCACTA ACCAGTATGA ACAAGCCATC TTCCATGTGG CCATCAGGCG CAGGTGCAGG 
CCCAGCCCCT ACGTGGTAAA CTTTCTGGTG CCCAGTGGCA TTCTGATTGC CATCGATGCC 
CTCAGTTTCT ACCTGCCACT GGAAAGTGGG AATTGTGCCC CATTCAAGAT GACTGTTCTG 
CTGGGCTACA GCGTCTTCCT GCTCATGATG AATGACTTGC TCCCAGCCAC TAGCACTTCA 
TCACATGCTT CACTAGTACG TCCTCATCCA TCAAGAGACC AAAAGCGAGG TGTCTACTTC 
GCCCTGTGCC TGTCCCTGAT GGTGGGCAGC CTGCTGGAGA CCATCTTCAT CACCCACCTG 
CTGCACGTGG CCACCACCCA GCCCCTACCT CTGCCTCGGT GGCTCCACTC CCTGCTGCTG 
CACTGCACCG GCCAAGGGAG ATGCTGTCCC ACTGCGCCCC AGAAGGGAAA TAAGGGCCCG 
GGTCTCACCC CCACCCACCT GCCCGGTGTG AAGGAGCCAG AGGTATCAGC AGGGCAGATG 
CCAGGCCCTG GGGAGGCAGA GCTGACAGGG GGCTCAGAAT GGACAAGGGC CCAGCGGGAA 
CACGAGGCCC AGAAGCAGCA CTCGGTGGAG CTGTGGGTGC AGTTCAGCCA CGCGATGGAC 
GCCCTGCTCT TCCGCCTCTA CCTGCTCTTC ATGGCCTCCT CCATCATCAC CGTCATATGC 
CTCTGGAACA CCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HTR3D ( XM_017005854.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016861343.1 Homo sapiens 5-hydroxytryptamine receptor 3D (HTR3D), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu93868
Clone ID Related Accession (Same CDS sequence)	XM_017005854.1
Accession Version	XM_017005854.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 702bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	5-hydroxytryptamine receptor 3D isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGGCCA TCAGGCGCAG GTGCAGGCCC AGCCCCTACG TGGTAAACTT TCTGGTGCCC 
AGTGGCATTC TGATTGCCAT CGATGCCCTC AGTTTCTACC TGCCACTGGA AAGTGGGAAT 
TGTGCCCCAT TCAAGATGAC TGTTCTGCTG GGCTACAGCG TCTTCCTGCT CATGATGAAT 
GACTTGCTCC CAGCCACTAG CACTTCATCA CATGCTTCAC TAGTACGTCC TCATCCATCA 
AGAGACCAAA AGCGAGGTGT CTACTTCGCC CTGTGCCTGT CCCTGATGGT GGGCAGCCTG 
CTGGAGACCA TCTTCATCAC CCACCTGCTG CACGTGGCCA CCACCCAGCC CCTACCTCTG 
CCTCGGTGGC TCCACTCCCT GCTGCTGCAC TGCACCGGCC AAGGGAGATG CTGTCCCACT 
GCGCCCCAGA AGGGAAATAA GGGCCCGGGT CTCACCCCCA CCCACCTGCC CGGTGTGAAG 
GAGCCAGAGG TATCAGCAGG GCAGATGCCA GGCCCTGGGG AGGCAGAGCT GACAGGGGGC 
TCAGAATGGA CAAGGGCCCA GCGGGAACAC GAGGCCCAGA AGCAGCACTC GGTGGAGCTG 
TGGGTGCAGT TCAGCCACGC GATGGACGCC CTGCTCTTCC GCCTCTACCT GCTCTTCATG 
GCCTCCTCCA TCATCACCGT CATATGCCTC TGGAACACCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016861343.1
CDS	117..818
Translation	MVAIRRRCRPSPYVVNFLVPSGILIAIDALSFYLPLESGNCAPFKMTVLLGYSVFLLMMNDLLPATSTSSHASLVRPHPSRDQKRGVYFALCLSLMVGSLLETIFITHLLHVATTQPLPLPRWLHSLLLHCTGQGRCCPTAPQKGNKGPGLTPTHLPGVKEPEVSAGQMPGPGEAELTGGSEWTRAQREHEAQKQHSVELWVQFSHAMDALLFRLYLLFMASSIITVICLWNT

Target ORF information:

RefSeq Version	XM_017005854.1
Organism	Homo sapiens(human)
Definition	Homo sapiens 5-hydroxytryptamine receptor 3D (HTR3D), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017005854.1

ORF Insert Sequence:

ATGGTGGCCA TCAGGCGCAG GTGCAGGCCC AGCCCCTACG TGGTAAACTT TCTGGTGCCC 
AGTGGCATTC TGATTGCCAT CGATGCCCTC AGTTTCTACC TGCCACTGGA AAGTGGGAAT 
TGTGCCCCAT TCAAGATGAC TGTTCTGCTG GGCTACAGCG TCTTCCTGCT CATGATGAAT 
GACTTGCTCC CAGCCACTAG CACTTCATCA CATGCTTCAC TAGTACGTCC TCATCCATCA 
AGAGACCAAA AGCGAGGTGT CTACTTCGCC CTGTGCCTGT CCCTGATGGT GGGCAGCCTG 
CTGGAGACCA TCTTCATCAC CCACCTGCTG CACGTGGCCA CCACCCAGCC CCTACCTCTG 
CCTCGGTGGC TCCACTCCCT GCTGCTGCAC TGCACCGGCC AAGGGAGATG CTGTCCCACT 
GCGCCCCAGA AGGGAAATAA GGGCCCGGGT CTCACCCCCA CCCACCTGCC CGGTGTGAAG 
GAGCCAGAGG TATCAGCAGG GCAGATGCCA GGCCCTGGGG AGGCAGAGCT GACAGGGGGC 
TCAGAATGGA CAAGGGCCCA GCGGGAACAC GAGGCCCAGA AGCAGCACTC GGTGGAGCTG 
TGGGTGCAGT TCAGCCACGC GATGGACGCC CTGCTCTTCC GCCTCTACCT GCTCTTCATG 
GCCTCCTCCA TCATCACCGT CATATGCCTC TGGAACACCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genetic Association of the PARL-ABCC5-HTR3D-HTR3C Locus With Primary Angle-Closure Glaucoma in Chinese.
Investigative ophthalmology & visual science58(10)4384?4389(2017 08)
Tang FY,Ma L,Tam POS,Pang CP,Tham CCY,Chen LJ

ABCC5, a gene that influences the anterior chamber depth, is associated with primary angle closure glaucoma.
PLoS genetics10(3)e1004089(2014 Mar)
Nongpiur ME,Khor CC,Jia H,Cornes BK,Chen LJ,Qiao C,Nair KS,Cheng CY,Xu L,George R,Tan D,Abu-Amero K,Perera SA,Ozaki M,Mizoguchi T,Kurimoto Y,Low S,Tajudin LS,Ho CL,Tham CC,Soto I,Chew PT,Wong HT,Shantha B,Kuroda M,Osman EA,Tang G,Fan S,Meng H,Wang H,Feng B,Yong VH,Ting SM,Li Y,Wang YX,Li Z,Lavanya R,Wu RY,Zheng YF,Su DH,Loon SC,Yong VK,Allingham RR,Hauser MA,Soumittra N,Ramprasad VL,Waseem N,Yaakub A,Chia KS,Kumaramanickavel G,Wong TT,How AC,Chau TN,Simmons CP,Bei JX,Zeng YX,Bhattacharya SS,Zhang M,Tan DT,Teo YY,Al-Obeidan SA,Hon DN,Tai ES,Saw SM,Foster PJ,Vijaya L,Jonas JB,Wong TY,John SW,Pang CP,Vithana EN,Wang N,Aung T

A mega-analysis of genome-wide association studies for major depressive disorder.
Molecular psychiatry18(4)497-511(2013 Apr)
,Ripke S,Wray NR,Lewis CM,Hamilton SP,Weissman MM,Breen G,Byrne EM,Blackwood DH,Boomsma DI,Cichon S,Heath AC,Holsboer F,Lucae S,Madden PA,Martin NG,McGuffin P,Muglia P,Noethen MM,Penninx BP,Pergadia ML,Potash JB,Rietschel M,Lin D,M?ller-Myhsok B,Shi J,Steinberg S,Grabe HJ,Lichtenstein P,Magnusson P,Perlis RH,Preisig M,Smoller JW,Stefansson K,Uher R,Kutalik Z,Tansey KE,Teumer A,Viktorin A,Barnes MR,Bettecken T,Binder EB,Breuer R,Castro VM,Churchill SE,Coryell WH,Craddock N,Craig IW,Czamara D,De Geus EJ,Degenhardt F,Farmer AE,Fava M,Frank J,Gainer VS,Gallagher PJ,Gordon SD,Goryachev S,Gross M,Guipponi M,Henders AK,Herms S,Hickie IB,Hoefels S,Hoogendijk W,Hottenga JJ,Iosifescu DV,Ising M,Jones I,Jones L,Jung-Ying T,Knowles JA,Kohane IS,Kohli MA,Korszun A,Landen M,Lawson WB,Lewis G,Macintyre D,Maier W,Mattheisen M,McGrath PJ,McIntosh A,McLean A,Middeldorp CM,Middleton L,Montgomery GM,Murphy SN,Nauck M,Nolen WA,Nyholt DR,O'Donovan M,Oskarsson H,Pedersen N,Scheftner WA,Schulz A,Schulze TG,Shyn SI,Sigurdsson E,Slager SL,Smit JH,Stefansson H,Steffens M,Thorgeirsson T,Tozzi F,Treutlein J,Uhr M,van den Oord EJ,Van Grootheest G,V?lzke H,Weilburg JB,Willemsen G,Zitman FG,Neale B,Daly M,Levinson DF,Sullivan PF

Serotonin receptor diversity in the human colon: Expression of serotonin type 3 receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E.
The Journal of comparative neurology519(3)420-32(2011 Feb)
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HTR3D cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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