TMEM17 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TMEM17
Entrez Gene ID	200728
Full Name	transmembrane protein 17
General protein information	Preferred Names transmembrane protein 17 Names transmembrane protein 17
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2p15
Disorder MIM:	614950

mRNA and Protein(s)

mRNA	Protein	Name
NM_198276.3	NP_938017.2	transmembrane protein 17
XM_011532693.2	XP_011530995.1	transmembrane protein 17 isoform X3
XM_017003575.1	XP_016859064.1	transmembrane protein 17 isoform X1
XM_024452749.1	XP_024308517.1	transmembrane protein 17 isoform X1
XM_011532694.2	XP_011530996.1	transmembrane protein 17 isoform X4
NM_198276.2	NP_938017.2	transmembrane protein 17
XM_024452750.1	XP_024308518.1	transmembrane protein 17 isoform X2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	TMEM17	XP_531842.1
Bos taurus (cattle)	TMEM17	NP_001076902.1
Xenopus tropicalis (tropical clawed frog)	tmem17	NP_001015683.1
Gallus gallus (chicken)	TMEM17	NP_001263317.1
Homo sapiens (human)	TMEM17	NP_938017.2
Danio rerio (zebrafish)	tmem17	NP_001091861.1
Pan troglodytes (chimpanzee)	TMEM17	XP_001161917.1
	TMEM17	XP_001083080.1
Mus musculus (house mouse)	Tmem17	NP_705824.1
Rattus norvegicus (Norway rat)	Tmem17	NP_001010961.1

Gene Ontology
Bibliography

Related articles in PubMed

TMEM17 depresses invasion and metastasis in lung cancer cells via ERK signaling pathway.
Zhang X, Zhang Y, Miao Y, Zhou H, Jiang G, Wang E
Oncotarget8(41)70685-70694(2017 Sep)

MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone.
Li C, Jensen VL, Park K, Kennedy J, Garcia-Gonzalo FR, Romani M, De Mori R, Bruel AL, Gaillard D, Doray B, Lopez E, Rivi?re JB, Faivre L, Thauvin-Robinet C, Reiter JF, Blacque OE, Valente EM, Leroux MR
PLoS biology14(3)e1002416(2016 Mar)

A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
Gupta GD, Coyaud ?, Gon?alves J, Mojarad BA, Liu Y, Wu Q, Gheiratmand L, Comartin D, Tkach JM, Cheung SW, Bashkurov M, Hasegan M, Knight JD, Lin ZY, Schueler M, Hildebrandt F, Moffat J, Gingras AC, Raught B, Pelletier L
Cell163(6)1484-99(2015 Dec)

A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.
Kenny EE, Pe'er I, Karban A, Ozelius L, Mitchell AA, Ng SM, Erazo M, Ostrer H, Abraham C, Abreu MT, Atzmon G, Barzilai N, Brant SR, Bressman S, Burns ER, Chowers Y, Clark LN, Darvasi A, Doheny D, Duerr RH, Eliakim R, Giladi N, Gregersen PK, Hakonarson H, Jones MR, Marder K, McGovern DP, Mulle J, Orr-Urtreger A, Proctor DD, Pulver A, Rotter JI, Silverberg MS, Ullman T, Warren ST, Waterman M, Zhang W, Bergman A, Mayer L, Katz S, Desnick RJ, Cho JH, Peter I
PLoS genetics8(3)e1002559(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TMEM17 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TMEM17 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu31413	NM_198276.3 Latest version!	Homo sapiens transmembrane protein 17 (TMEM17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu77675	XM_011532693.2 Latest version!	Homo sapiens transmembrane protein 17 (TMEM17), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu77676	XM_011532694.2 Latest version!	Homo sapiens transmembrane protein 17 (TMEM17), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu104828	XM_024452749.1 Latest version!	Homo sapiens transmembrane protein 17 (TMEM17), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu89147	XM_017003575.1 Latest version!	Homo sapiens transmembrane protein 17 (TMEM17), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu89147	XM_024452750.1 Latest version!	Homo sapiens transmembrane protein 17 (TMEM17), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu31413	NM_198276.2	Homo sapiens transmembrane protein 17 (TMEM17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TMEM17 ( NM_198276.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_938017.2 Homo sapiens transmembrane protein 17 (TMEM17), mRNA.

Price & Availability↑

CloneID	OHu31413
Clone ID Related Accession (Same CDS sequence)	NM_198276.3 , NM_198276.2
Accession Version	NM_198276.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	transmembrane protein 17
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DR760587.1, BC047439.1 and AC093159.3. On Nov 22, 2018 this sequence version replaced NM_198276.2. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The extent of this RefSeq transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.1113291.1, SRR5189667.224371.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267775 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000335390.6/ ENSP00000335094.5 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCTGC CGGATCCGGT GCGCCAGCGG CTGGGAAACT TCAGCCGGGC CGTGTTCAGT 
GATTCCAATC GGACCGGTCC AGAGTCCAAT GAGGGTCCGG AAAATGAAAT GGTCTCCAGT 
TTGGCACTGC AGATGTCACT TTATTTTAAT ACCTACTATT TCCCACTGTG GTGGGTGAGC 
AGCATTATGA TGCTTCACAT GAAGTATTCA ATCTTACCTG ACTACTACAA ATTCATTGTG 
ATCACTGTTA TCATCCTAAT AACCTTAATT GAAGCCATCC GGTTGTATCT GGGCTACGTG 
GGTAACCTAC AGGAGAAGGT TCCTGAGTTG GCTGGCTTTT GGCTTTTGAG CCTTCTATTG 
CAGTTACCTT TAATTCTTTT CTTGCTCTTT AATGAAGGCC TAACAAATCT GCCCTTGGAA 
AAAGCGATAC ATATCATCTT CACTCTCTTC CTTGCTTTCC AAGTTGTTGC AGCATTTCTT 
ACCTTAAGGA AAATGGTTAA TCAGTTGGCA GTTCGTTTCC ACCTCCAAGA CTTTGACCGG 
CTCTCTGCAA ACAGAGGAGA CATGAGAAGG ATGAGGTCAT GTATAGAAGA GATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_938017.2
CDS	67..663
Translation	MELPDPVRQRLGNFSRAVFSDSNRTGPESNEGPENEMVSSLALQMSLYFNTYYFPLWWVSSIMMLHMKYSILPDYYKFIVITVIILITLIEAIRLYLGYVGNLQEKVPELAGFWLLSLLLQLPLILFLLFNEGLTNLPLEKAIHIIFTLFLAFQVVAAFLTLRKMVNQLAVRFHLQDFDRLSANRGDMRRMRSCIEEI

Target ORF information:

RefSeq Version	NM_198276.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 17 (TMEM17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198276.3

ORF Insert Sequence:

ATGGAGCTGC CGGATCCGGT GCGCCAGCGG CTGGGAAACT TCAGCCGGGC CGTGTTCAGT 
GATTCCAATC GGACCGGTCC AGAGTCCAAT GAGGGTCCGG AAAATGAAAT GGTCTCCAGT 
TTGGCACTGC AGATGTCACT TTATTTTAAT ACCTACTATT TCCCACTGTG GTGGGTGAGC 
AGCATTATGA TGCTTCACAT GAAGTATTCA ATCTTACCTG ACTACTACAA ATTCATTGTG 
ATCACTGTTA TCATCCTAAT AACCTTAATT GAAGCCATCC GGTTGTATCT GGGCTACGTG 
GGTAACCTAC AGGAGAAGGT TCCTGAGTTG GCTGGCTTTT GGCTTTTGAG CCTTCTATTG 
CAGTTACCTT TAATTCTTTT CTTGCTCTTT AATGAAGGCC TAACAAATCT GCCCTTGGAA 
AAAGCGATAC ATATCATCTT CACTCTCTTC CTTGCTTTCC AAGTTGTTGC AGCATTTCTT 
ACCTTAAGGA AAATGGTTAA TCAGTTGGCA GTTCGTTTCC ACCTCCAAGA CTTTGACCGG 
CTCTCTGCAA ACAGAGGAGA CATGAGAAGG ATGAGGTCAT GTATAGAAGA GATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM17 ( NM_198276.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_938017.2 Homo sapiens transmembrane protein 17 (TMEM17), mRNA.

Price & Availability↑

CloneID	OHu31413
Clone ID Related Accession (Same CDS sequence)	NM_198276.3 , NM_198276.2
Accession Version	NM_198276.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	transmembrane protein 17
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DR760587.1, BC047439.1 and AC093159.3. On Dec 13, 2008 this sequence version replaced NM_198276.1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The extent of this RefSeq transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.11562.1, SRR1660805.211026.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03267775 [ECO:0000348] ##Evidence-Data-END##

ATGGAGCTGC CGGATCCGGT GCGCCAGCGG CTGGGAAACT TCAGCCGGGC CGTGTTCAGT 
GATTCCAATC GGACCGGTCC AGAGTCCAAT GAGGGTCCGG AAAATGAAAT GGTCTCCAGT 
TTGGCACTGC AGATGTCACT TTATTTTAAT ACCTACTATT TCCCACTGTG GTGGGTGAGC 
AGCATTATGA TGCTTCACAT GAAGTATTCA ATCTTACCTG ACTACTACAA ATTCATTGTG 
ATCACTGTTA TCATCCTAAT AACCTTAATT GAAGCCATCC GGTTGTATCT GGGCTACGTG 
GGTAACCTAC AGGAGAAGGT TCCTGAGTTG GCTGGCTTTT GGCTTTTGAG CCTTCTATTG 
CAGTTACCTT TAATTCTTTT CTTGCTCTTT AATGAAGGCC TAACAAATCT GCCCTTGGAA 
AAAGCGATAC ATATCATCTT CACTCTCTTC CTTGCTTTCC AAGTTGTTGC AGCATTTCTT 
ACCTTAAGGA AAATGGTTAA TCAGTTGGCA GTTCGTTTCC ACCTCCAAGA CTTTGACCGG 
CTCTCTGCAA ACAGAGGAGA CATGAGAAGG ATGAGGTCAT GTATAGAAGA GATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_938017.2
CDS	341..937
Translation	MELPDPVRQRLGNFSRAVFSDSNRTGPESNEGPENEMVSSLALQMSLYFNTYYFPLWWVSSIMMLHMKYSILPDYYKFIVITVIILITLIEAIRLYLGYVGNLQEKVPELAGFWLLSLLLQLPLILFLLFNEGLTNLPLEKAIHIIFTLFLAFQVVAAFLTLRKMVNQLAVRFHLQDFDRLSANRGDMRRMRSCIEEI

Target ORF information:

RefSeq Version	NM_198276.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 17 (TMEM17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198276.2

ORF Insert Sequence:

ATGGAGCTGC CGGATCCGGT GCGCCAGCGG CTGGGAAACT TCAGCCGGGC CGTGTTCAGT 
GATTCCAATC GGACCGGTCC AGAGTCCAAT GAGGGTCCGG AAAATGAAAT GGTCTCCAGT 
TTGGCACTGC AGATGTCACT TTATTTTAAT ACCTACTATT TCCCACTGTG GTGGGTGAGC 
AGCATTATGA TGCTTCACAT GAAGTATTCA ATCTTACCTG ACTACTACAA ATTCATTGTG 
ATCACTGTTA TCATCCTAAT AACCTTAATT GAAGCCATCC GGTTGTATCT GGGCTACGTG 
GGTAACCTAC AGGAGAAGGT TCCTGAGTTG GCTGGCTTTT GGCTTTTGAG CCTTCTATTG 
CAGTTACCTT TAATTCTTTT CTTGCTCTTT AATGAAGGCC TAACAAATCT GCCCTTGGAA 
AAAGCGATAC ATATCATCTT CACTCTCTTC CTTGCTTTCC AAGTTGTTGC AGCATTTCTT 
ACCTTAAGGA AAATGGTTAA TCAGTTGGCA GTTCGTTTCC ACCTCCAAGA CTTTGACCGG 
CTCTCTGCAA ACAGAGGAGA CATGAGAAGG ATGAGGTCAT GTATAGAAGA GATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM17 ( XM_011532693.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011530995.1 Homo sapiens transmembrane protein 17 (TMEM17), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu77675
Clone ID Related Accession (Same CDS sequence)	XM_011532693.2
Accession Version	XM_011532693.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 504bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane protein 17 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011532693.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCTGC CGGATCCGGT GCGCCAGCGG CTGGGAAACT TCAGCCGGGC CGTGTTCAGT 
GATTCCAATC GGACCGGTCC AGAGTCCAAT GAGGGTCCGG AAAATGAAAT GGTCTCCAGT 
TTGGCACTGC AGATGTCACT TTATTTTAAT ACCTACTATT TCCCACTGTG GTGGGTGAGC 
AGCATTATGA TGCTTCACAT GAAGTATTCA ATCTTACCTG ACTACTACAA ATTCATTGTG 
ATCACTGTTA TCATCCTAAT AACCTTAATT GAAGCCATCC GGTTGTATCT GGGCTACGTG 
GGTAACCTAC AGGAGAAGAT GAGCGTGCTC GACATGTTGA GAATGGTGAC CACCAGAAGC 
CCCAGACTTA CCTCACAACT TTCAGGAGAC AAGGATCACA TCTTCCCTGG TAGAAAAGCT 
CTAGGGAAGT TTCTGTTTGA CCCAGCCTGG GTCAAGGCCT ATCGATGGAC CATTCATTGT 
GACCAACAGA ATAAGATGTT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011530995.1
CDS	341..844
Translation	MELPDPVRQRLGNFSRAVFSDSNRTGPESNEGPENEMVSSLALQMSLYFNTYYFPLWWVSSIMMLHMKYSILPDYYKFIVITVIILITLIEAIRLYLGYVGNLQEKMSVLDMLRMVTTRSPRLTSQLSGDKDHIFPGRKALGKFLFDPAWVKAYRWTIHCDQQNKMF

Target ORF information:

RefSeq Version	XM_011532693.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 17 (TMEM17), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011532693.2

ORF Insert Sequence:

ATGGAGCTGC CGGATCCGGT GCGCCAGCGG CTGGGAAACT TCAGCCGGGC CGTGTTCAGT 
GATTCCAATC GGACCGGTCC AGAGTCCAAT GAGGGTCCGG AAAATGAAAT GGTCTCCAGT 
TTGGCACTGC AGATGTCACT TTATTTTAAT ACCTACTATT TCCCACTGTG GTGGGTGAGC 
AGCATTATGA TGCTTCACAT GAAGTATTCA ATCTTACCTG ACTACTACAA ATTCATTGTG 
ATCACTGTTA TCATCCTAAT AACCTTAATT GAAGCCATCC GGTTGTATCT GGGCTACGTG 
GGTAACCTAC AGGAGAAGAT GAGCGTGCTC GACATGTTGA GAATGGTGAC CACCAGAAGC 
CCCAGACTTA CCTCACAACT TTCAGGAGAC AAGGATCACA TCTTCCCTGG TAGAAAAGCT 
CTAGGGAAGT TTCTGTTTGA CCCAGCCTGG GTCAAGGCCT ATCGATGGAC CATTCATTGT 
GACCAACAGA ATAAGATGTT CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM17 ( XM_011532694.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011530996.1 Homo sapiens transmembrane protein 17 (TMEM17), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu77676
Clone ID Related Accession (Same CDS sequence)	XM_011532694.2
Accession Version	XM_011532694.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 432bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane protein 17 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011532694.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCTGC CGGATCCGGT GCGCCAGCGG CTGGGAAACT TCAGCCGGGC CGTGTTCAGT 
GATTCCAATC GGACCGGTCC AGAGTCCAAT GAGGGTCCGG AAAATGAAAT GGTCTCCAGT 
TTGGCACTGC AGATGTCACT TTATTTTAAT ACCTACTATT TCCCACTGTG GTGGGTGAGC 
AGCATTATGA TGCTTCACAT GAAGTATTCA ATCTTACCTG ACTACTACAA ATTCATTGTG 
ATCACTGTTA TCATCCTAAT AACCTTAATT GAAGCCATCC GGTTGTATCT GGGCTACGTG 
GGTAACCTAC AGGAGAAGAA GATGGACAAG TTGAAGAAAC GTCACAGGAG CCCAAGAGGC 
TGGCCAGAGA GCCCAGGACT CAGTTCCTCT GTGGGAAGGC ACACACACTC TGGTGAAGCT 
GTCAGGCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011530996.1
CDS	341..772
Translation	MELPDPVRQRLGNFSRAVFSDSNRTGPESNEGPENEMVSSLALQMSLYFNTYYFPLWWVSSIMMLHMKYSILPDYYKFIVITVIILITLIEAIRLYLGYVGNLQEKKMDKLKKRHRSPRGWPESPGLSSSVGRHTHSGEAVRL

Target ORF information:

RefSeq Version	XM_011532694.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 17 (TMEM17), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011532694.2

ORF Insert Sequence:

ATGGAGCTGC CGGATCCGGT GCGCCAGCGG CTGGGAAACT TCAGCCGGGC CGTGTTCAGT 
GATTCCAATC GGACCGGTCC AGAGTCCAAT GAGGGTCCGG AAAATGAAAT GGTCTCCAGT 
TTGGCACTGC AGATGTCACT TTATTTTAAT ACCTACTATT TCCCACTGTG GTGGGTGAGC 
AGCATTATGA TGCTTCACAT GAAGTATTCA ATCTTACCTG ACTACTACAA ATTCATTGTG 
ATCACTGTTA TCATCCTAAT AACCTTAATT GAAGCCATCC GGTTGTATCT GGGCTACGTG 
GGTAACCTAC AGGAGAAGAA GATGGACAAG TTGAAGAAAC GTCACAGGAG CCCAAGAGGC 
TGGCCAGAGA GCCCAGGACT CAGTTCCTCT GTGGGAAGGC ACACACACTC TGGTGAAGCT 
GTCAGGCTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM17 ( XM_024452749.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024308517.1 Homo sapiens transmembrane protein 17 (TMEM17), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu104828
Clone ID Related Accession (Same CDS sequence)	XM_024452749.1
Accession Version	XM_024452749.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 639bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane protein 17 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCTGC CGGATCCGGT GCGCCAGCGG CTGGGAAACT TCAGCCGGGC CGTGTTCAGT 
GATTCCAATC GGACCGGTCC AGAGTCCAAT GAGGGTCCGG AAAATGAAAT GGTCTCCAGT 
TTGGCACTGC AGATGTCACT TTATTTTAAT ACCTACTATT TCCCACTGTG GTGGGTGAGC 
AGCATTATGA TGCTTCACAT GAAGTATTCA ATCTTACCTG ACTACTACAA ATTCATTGTG 
ATCACTGTTA TCATCCTAAT AACCTTAATT GAAGCCATCC GGTTGTATCT GGGCTACGTG 
GGTAACCTAC AGGAGAAGAA GATGGACAAG TTGAAGAAAC GTCACAGGAG CCCAAGAGGC 
TGGCCAGAGA GCCCAGGACT CAGTTCCTCT GTGGGAAGGC ACACACACTC TTTGGTCAAG 
AAACTTGGTC AGGAGGTCAG AAACATGGGC CCTGCCCGAG CAGCAAGTCA CCATGACCCA 
GGCCAACCTG AGGACAAAGG CCTCAACTAT TCCTTGAACC ATGCTGATAA TCAGGACATT 
CCGAAGAAAC AAGTGATGTG GATTTCAGTG ACGGCCTACC TCCAGAAGAC TTCCTTCAGC 
CTGATGTCTT CCTCAAGACC AGCCAACCCC GAACCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024308517.1
CDS	341..979
Translation	MELPDPVRQRLGNFSRAVFSDSNRTGPESNEGPENEMVSSLALQMSLYFNTYYFPLWWVSSIMMLHMKYSILPDYYKFIVITVIILITLIEAIRLYLGYVGNLQEKKMDKLKKRHRSPRGWPESPGLSSSVGRHTHSLVKKLGQEVRNMGPARAASHHDPGQPEDKGLNYSLNHADNQDIPKKQVMWISVTAYLQKTSFSLMSSSRPANPEP

Target ORF information:

RefSeq Version	XM_024452749.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 17 (TMEM17), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024452749.1

ORF Insert Sequence:

ATGGAGCTGC CGGATCCGGT GCGCCAGCGG CTGGGAAACT TCAGCCGGGC CGTGTTCAGT 
GATTCCAATC GGACCGGTCC AGAGTCCAAT GAGGGTCCGG AAAATGAAAT GGTCTCCAGT 
TTGGCACTGC AGATGTCACT TTATTTTAAT ACCTACTATT TCCCACTGTG GTGGGTGAGC 
AGCATTATGA TGCTTCACAT GAAGTATTCA ATCTTACCTG ACTACTACAA ATTCATTGTG 
ATCACTGTTA TCATCCTAAT AACCTTAATT GAAGCCATCC GGTTGTATCT GGGCTACGTG 
GGTAACCTAC AGGAGAAGAA GATGGACAAG TTGAAGAAAC GTCACAGGAG CCCAAGAGGC 
TGGCCAGAGA GCCCAGGACT CAGTTCCTCT GTGGGAAGGC ACACACACTC TTTGGTCAAG 
AAACTTGGTC AGGAGGTCAG AAACATGGGC CCTGCCCGAG CAGCAAGTCA CCATGACCCA 
GGCCAACCTG AGGACAAAGG CCTCAACTAT TCCTTGAACC ATGCTGATAA TCAGGACATT 
CCGAAGAAAC AAGTGATGTG GATTTCAGTG ACGGCCTACC TCCAGAAGAC TTCCTTCAGC 
CTGATGTCTT CCTCAAGACC AGCCAACCCC GAACCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM17 ( XM_017003575.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016859064.1 Homo sapiens transmembrane protein 17 (TMEM17), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu89147
Clone ID Related Accession (Same CDS sequence)	XM_017003575.1 , XM_024452750.1
Accession Version	XM_017003575.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 522bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	transmembrane protein 17 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCAGC TGCTTCATAT AGCAGAAAAT GAAATGGTCT CCAGTTTGGC ACTGCAGATG 
TCACTTTATT TTAATACCTA CTATTTCCCA CTGTGGTGGG TGAGCAGCAT TATGATGCTT 
CACATGAAGT ATTCAATCTT ACCTGACTAC TACAAATTCA TTGTGATCAC TGTTATCATC 
CTAATAACCT TAATTGAAGC CATCCGGTTG TATCTGGGCT ACGTGGGTAA CCTACAGGAG 
AAGGTTCCTG AGTTGGCTGG CTTTTGGCTT TTGAGCCTTC TATTGCAGTT ACCTTTAATT 
CTTTTCTTGC TCTTTAATGA AGGCCTAACA AATCTGCCCT TGGAAAAAGC GATACATATC 
ATCTTCACTC TCTTCCTTGC TTTCCAAGTT GTTGCAGCAT TTCTTACCTT AAGGAAAATG 
GTTAATCAGT TGGCAGTTCG TTTCCACCTC CAAGACTTTG ACCGGCTCTC TGCAAACAGA 
GGAGACATGA GAAGGATGAG GTCATGTATA GAAGAGATCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016859064.1
CDS	327..848
Translation	MEQLLHIAENEMVSSLALQMSLYFNTYYFPLWWVSSIMMLHMKYSILPDYYKFIVITVIILITLIEAIRLYLGYVGNLQEKVPELAGFWLLSLLLQLPLILFLLFNEGLTNLPLEKAIHIIFTLFLAFQVVAAFLTLRKMVNQLAVRFHLQDFDRLSANRGDMRRMRSCIEEI

Target ORF information:

RefSeq Version	XM_017003575.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 17 (TMEM17), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017003575.1

ORF Insert Sequence:

ATGGAGCAGC TGCTTCATAT AGCAGAAAAT GAAATGGTCT CCAGTTTGGC ACTGCAGATG 
TCACTTTATT TTAATACCTA CTATTTCCCA CTGTGGTGGG TGAGCAGCAT TATGATGCTT 
CACATGAAGT ATTCAATCTT ACCTGACTAC TACAAATTCA TTGTGATCAC TGTTATCATC 
CTAATAACCT TAATTGAAGC CATCCGGTTG TATCTGGGCT ACGTGGGTAA CCTACAGGAG 
AAGGTTCCTG AGTTGGCTGG CTTTTGGCTT TTGAGCCTTC TATTGCAGTT ACCTTTAATT 
CTTTTCTTGC TCTTTAATGA AGGCCTAACA AATCTGCCCT TGGAAAAAGC GATACATATC 
ATCTTCACTC TCTTCCTTGC TTTCCAAGTT GTTGCAGCAT TTCTTACCTT AAGGAAAATG 
GTTAATCAGT TGGCAGTTCG TTTCCACCTC CAAGACTTTG ACCGGCTCTC TGCAAACAGA 
GGAGACATGA GAAGGATGAG GTCATGTATA GAAGAGATCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM17 ( XM_024452750.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024308518.1 Homo sapiens transmembrane protein 17 (TMEM17), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu89147
Clone ID Related Accession (Same CDS sequence)	XM_017003575.1 , XM_024452750.1
Accession Version	XM_024452750.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 522bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane protein 17 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCAGC TGCTTCATAT AGCAGAAAAT GAAATGGTCT CCAGTTTGGC ACTGCAGATG 
TCACTTTATT TTAATACCTA CTATTTCCCA CTGTGGTGGG TGAGCAGCAT TATGATGCTT 
CACATGAAGT ATTCAATCTT ACCTGACTAC TACAAATTCA TTGTGATCAC TGTTATCATC 
CTAATAACCT TAATTGAAGC CATCCGGTTG TATCTGGGCT ACGTGGGTAA CCTACAGGAG 
AAGGTTCCTG AGTTGGCTGG CTTTTGGCTT TTGAGCCTTC TATTGCAGTT ACCTTTAATT 
CTTTTCTTGC TCTTTAATGA AGGCCTAACA AATCTGCCCT TGGAAAAAGC GATACATATC 
ATCTTCACTC TCTTCCTTGC TTTCCAAGTT GTTGCAGCAT TTCTTACCTT AAGGAAAATG 
GTTAATCAGT TGGCAGTTCG TTTCCACCTC CAAGACTTTG ACCGGCTCTC TGCAAACAGA 
GGAGACATGA GAAGGATGAG GTCATGTATA GAAGAGATCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024308518.1
CDS	84..605
Translation	MEQLLHIAENEMVSSLALQMSLYFNTYYFPLWWVSSIMMLHMKYSILPDYYKFIVITVIILITLIEAIRLYLGYVGNLQEKVPELAGFWLLSLLLQLPLILFLLFNEGLTNLPLEKAIHIIFTLFLAFQVVAAFLTLRKMVNQLAVRFHLQDFDRLSANRGDMRRMRSCIEEI

Target ORF information:

RefSeq Version	XM_024452750.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 17 (TMEM17), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024452750.1

ORF Insert Sequence:

ATGGAGCAGC TGCTTCATAT AGCAGAAAAT GAAATGGTCT CCAGTTTGGC ACTGCAGATG 
TCACTTTATT TTAATACCTA CTATTTCCCA CTGTGGTGGG TGAGCAGCAT TATGATGCTT 
CACATGAAGT ATTCAATCTT ACCTGACTAC TACAAATTCA TTGTGATCAC TGTTATCATC 
CTAATAACCT TAATTGAAGC CATCCGGTTG TATCTGGGCT ACGTGGGTAA CCTACAGGAG 
AAGGTTCCTG AGTTGGCTGG CTTTTGGCTT TTGAGCCTTC TATTGCAGTT ACCTTTAATT 
CTTTTCTTGC TCTTTAATGA AGGCCTAACA AATCTGCCCT TGGAAAAAGC GATACATATC 
ATCTTCACTC TCTTCCTTGC TTTCCAAGTT GTTGCAGCAT TTCTTACCTT AAGGAAAATG 
GTTAATCAGT TGGCAGTTCG TTTCCACCTC CAAGACTTTG ACCGGCTCTC TGCAAACAGA 
GGAGACATGA GAAGGATGAG GTCATGTATA GAAGAGATCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TMEM17 depresses invasion and metastasis in lung cancer cells via ERK signaling pathway.
Oncotarget8(41)70685-70694(2017 Sep)
Zhang X,Zhang Y,Miao Y,Zhou H,Jiang G,Wang E

MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone.
PLoS biology14(3)e1002416(2016 Mar)
Li C,Jensen VL,Park K,Kennedy J,Garcia-Gonzalo FR,Romani M,De Mori R,Bruel AL,Gaillard D,Doray B,Lopez E,Rivi?re JB,Faivre L,Thauvin-Robinet C,Reiter JF,Blacque OE,Valente EM,Leroux MR

A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.
Cell163(6)1484-99(2015 Dec)
Gupta GD,Coyaud ?,Gon?alves J,Mojarad BA,Liu Y,Wu Q,Gheiratmand L,Comartin D,Tkach JM,Cheung SW,Bashkurov M,Hasegan M,Knight JD,Lin ZY,Schueler M,Hildebrandt F,Moffat J,Gingras AC,Raught B,Pelletier L

A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.
PLoS genetics8(3)e1002559(2012)
Kenny EE,Pe'er I,Karban A,Ozelius L,Mitchell AA,Ng SM,Erazo M,Ostrer H,Abraham C,Abreu MT,Atzmon G,Barzilai N,Brant SR,Bressman S,Burns ER,Chowers Y,Clark LN,Darvasi A,Doheny D,Duerr RH,Eliakim R,Giladi N,Gregersen PK,Hakonarson H,Jones MR,Marder K,McGovern DP,Mulle J,Orr-Urtreger A,Proctor DD,Pulver A,Rotter JI,Silverberg MS,Ullman T,Warren ST,Waterman M,Zhang W,Bergman A,Mayer L,Katz S,Desnick RJ,Cho JH,Peter I

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TMEM17 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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