A2M gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
NM_001347425.2	NP_001334354.2	alpha-2-macroglobulin isoform c
NM_001347424.1	NP_001334353.1	alpha-2-macroglobulin isoform b
NM_001347423.1	NP_001334352.1	alpha-2-macroglobulin isoform a precursor
NM_001347425.1	NP_001334354.1	alpha-2-macroglobulin isoform c
XM_006719056.3	XP_006719119.1	alpha-2-macroglobulin isoform X1
NM_001347424.2	NP_001334353.2	alpha-2-macroglobulin isoform b
NM_000014.5	NP_000005.2	alpha-2-macroglobulin isoform a precursor
NM_001347423.2	NP_001334352.2	alpha-2-macroglobulin isoform a precursor
NM_000014.6	NP_000005.3	alpha-2-macroglobulin isoform a precursor
XM_006719056.2	XP_006719119.1	alpha-2-macroglobulin isoform X1

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18488	NM_000014.5 Latest version!	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$519.50-$727.30 $1039.00
OHu102221	NM_001347424.1 Latest version!	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$727.30 $1039.00
OHu102390	NM_001347425.1 Latest version!	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
OHu108400	NM_001347423.2 Latest version!	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$727.30 $1039.00
OHu108400	NM_000014.6 Latest version!	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$727.30 $1039.00
OHu109274	NM_001347424.2 Latest version!	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$727.30 $1039.00
OHu109275	NM_001347425.2 Latest version!	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$643.30 $919.00
OHu18488	NM_001347423.1 Latest version!	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$727.30 $1039.00
OHu46081	XM_006719056.3 Latest version!	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$811.30 $1159.00
View Old Accession Versions >>
OHu46081	XM_006719056.2	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$811.30 $1159.00
Hide Old Accession Versions >>

A2M ( NM_000014.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_000005.2 Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18488
Clone ID Related Accession (Same CDS sequence)	NM_001347423.1 , NM_000014.5
Accession Version	NM_000014.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4425bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-27
Organism	Homo sapiens(human)
Product	alpha-2-macroglobulin isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC334781.1, DC402196.1, BC040071.1 and AB209614.2. On Nov 26, 2016 this sequence version replaced NM_000014.4. Transcript Variant: This variant (1) encodes the longest isoform (a). Both variants 1 and 2 encode isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC040071.1, SRR1660809.61793.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGAAGA ACAAACTCCT TCATCCAAGT CTGGTTCTTC TCCTCTTGGT CCTCCTGCCC 
ACAGACGCCT CAGTCTCTGG AAAACCGCAG TATATGGTTC TGGTCCCCTC CCTGCTCCAC 
ACTGAGACCA CTGAGAAGGG CTGTGTCCTT CTGAGCTACC TGAATGAGAC AGTGACTGTA 
AGTGCTTCCT TGGAGTCTGT CAGGGGAAAC AGGAGCCTCT TCACTGACCT GGAGGCGGAG 
AATGACGTAC TCCACTGTGT CGCCTTCGCT GTCCCAAAGT CTTCATCCAA TGAGGAGGTA 
ATGTTCCTCA CTGTCCAAGT GAAAGGACCA ACCCAAGAAT TTAAGAAGCG GACCACAGTG 
ATGGTTAAGA ACGAGGACAG TCTGGTCTTT GTCCAGACAG ACAAATCAAT CTACAAACCA 
GGGCAGACAG TGAAATTTCG TGTTGTCTCC ATGGATGAAA ACTTTCACCC CCTGAATGAG 
TTGATTCCAC TAGTATACAT TCAGGATCCC AAAGGAAATC GCATCGCACA ATGGCAGAGT 
TTCCAGTTAG AGGGTGGCCT CAAGCAATTT TCTTTTCCCC TCTCATCAGA GCCCTTCCAG 
GGCTCCTACA AGGTGGTGGT ACAGAAGAAA TCAGGTGGAA GGACAGAGCA CCCTTTCACC 
GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA GTACAAGTAA CAGTGCCAAA GATAATCACC 
ATCTTGGAAG AAGAGATGAA TGTATCAGTG TGTGGCCTAT ACACATATGG GAAGCCTGTC 
CCTGGACATG TGACTGTGAG CATTTGCAGA AAGTATAGTG ACGCTTCCGA CTGCCACGGT 
GAAGATTCAC AGGCTTTCTG TGAGAAATTC AGTGGACAGC TAAACAGCCA TGGCTGCTTC 
TATCAGCAAG TAAAAACCAA GGTCTTCCAG CTGAAGAGGA AGGAGTATGA AATGAAACTT 
CACACTGAGG CCCAGATCCA AGAAGAAGGA ACAGTGGTGG AATTGACTGG AAGGCAGTCC 
AGTGAAATCA CAAGAACCAT AACCAAACTC TCATTTGTGA AAGTGGACTC ACACTTTCGA 
CAGGGAATTC CCTTCTTTGG GCAGGTGCGC CTAGTAGATG GGAAAGGCGT CCCTATACCA 
AATAAAGTCA TATTCATCAG AGGAAATGAA GCAAACTATT ACTCCAATGC TACCACGGAT 
GAGCATGGCC TTGTACAGTT CTCTATCAAC ACCACCAATG TTATGGGTAC CTCTCTTACT 
GTTAGGGTCA ATTACAAGGA TCGTAGTCCC TGTTACGGCT ACCAGTGGGT GTCAGAAGAA 
CACGAAGAGG CACATCACAC TGCTTATCTT GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC 
CTTGAGCCCA TGTCTCATGA ACTACCCTGT GGCCATACTC AGACAGTCCA GGCACATTAT 
ATTCTGAATG GAGGCACCCT GCTGGGGCTG AAGAAGCTCT CCTTCTATTA TCTGATAATG 
GCAAAGGGAG GCATTGTCCG AACTGGGACT CATGGACTGC TTGTGAAGCA GGAAGACATG 
AAGGGCCATT TTTCCATCTC AATCCCTGTG AAGTCAGACA TTGCTCCTGT CGCTCGGTTG 
CTCATCTATG CTGTTTTACC TACCGGGGAC GTGATTGGGG ATTCTGCAAA ATATGATGTT 
GAAAATTGTC TGGCCAACAA GGTGGATTTG AGCTTCAGCC CATCACAAAG TCTCCCAGCC 
TCACACGCCC ACCTGCGAGT CACAGCGGCT CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG 
GACCAAAGCG TGCTGCTCAT GAAGCCTGAT GCTGAGCTCT CGGCGTCCTC GGTTTACAAC 
CTGCTACCAG AAAAGGACCT CACTGGCTTC CCTGGGCCTT TGAATGACCA GGACGATGAA 
GACTGCATCA ATCGTCATAA TGTCTATATT AATGGAATCA CATATACTCC AGTATCAAGT 
ACAAATGAAA AGGATATGTA CAGCTTCCTA GAGGACATGG GCTTAAAGGC ATTCACCAAC 
TCAAAGATTC GTAAACCCAA AATGTGTCCA CAGCTTCAAC AGTATGAAAT GCATGGACCT 
GAAGGTCTAC GTGTAGGTTT TTATGAGTCA GATGTAATGG GAAGAGGCCA TGCACGCCTG 
GTGCATGTTG AAGAGCCTCA CACGGAGACC GTACGAAAGT ACTTCCCTGA GACATGGATC 
TGGGATTTGG TGGTGGTAAA CTCAGCAGGT GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC 
ACCATCACCG AGTGGAAGGC AGGGGCCTTC TGCCTGTCTG AAGATGCTGG ACTTGGTATC 
TCTTCCACTG CCTCTCTCCG AGCCTTCCAG CCCTTCTTTG TGGAGCTCAC AATGCCTTAC 
TCTGTGATTC GTGGAGAGGC CTTCACACTC AAGGCCACGG TCCTAAACTA CCTTCCCAAA 
TGCATCCGGG TCAGTGTGCA GCTGGAAGCC TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG 
AAGGAACAAG CGCCTCACTG CATCTGTGCA AACGGGCGGC AAACTGTGTC CTGGGCAGTA 
ACCCCAAAGT CATTAGGAAA TGTGAATTTC ACTGTGAGCG CAGAGGCACT AGAGTCTCAA 
GAGCTGTGTG GGACTGAGGT GCCTTCAGTT CCTGAACACG GAAGGAAAGA CACAGTCATC 
AAGCCTCTGT TGGTTGAACC TGAAGGACTA GAGAAGGAAA CAACATTCAA CTCCCTACTT 
TGTCCATCAG GTGGTGAGGT TTCTGAAGAA TTATCCCTGA AACTGCCACC AAATGTGGTA 
GAAGAATCTG CCCGAGCTTC TGTCTCAGTT TTGGGAGACA TATTAGGCTC TGCCATGCAA 
AACACACAAA ATCTTCTCCA GATGCCCTAT GGCTGTGGAG AGCAGAATAT GGTCCTCTTT 
GCTCCTAACA TCTATGTACT GGATTATCTA AATGAAACAC AGCAGCTTAC TCCAGAGATC 
AAGTCCAAGG CCATTGGCTA TCTCAACACT GGTTACCAGA GACAGTTGAA CTACAAACAC 
TATGATGGCT CCTACAGCAC CTTTGGGGAG CGATATGGCA GGAACCAGGG CAACACCTGG 
CTCACAGCCT TTGTTCTGAA GACTTTTGCC CAAGCTCGAG CCTACATCTT CATCGATGAA 
GCACACATTA CCCAAGCCCT CATATGGCTC TCCCAGAGGC AGAAGGACAA TGGCTGTTTC 
AGGAGCTCTG GGTCACTGCT CAACAATGCC ATAAAGGGAG GAGTAGAAGA TGAAGTGACC 
CTCTCCGCCT ATATCACCAT CGCCCTTCTG GAGATTCCTC TCACAGTCAC TCACCCTGTT 
GTCCGCAATG CCCTGTTTTG CCTGGAGTCA GCCTGGAAGA CAGCACAAGA AGGGGACCAT 
GGCAGCCATG TATATACCAA AGCACTGCTG GCCTATGCTT TTGCCCTGGC AGGTAACCAG 
GACAAGAGGA AGGAAGTACT CAAGTCACTT AATGAGGAAG CTGTGAAGAA AGACAACTCT 
GTCCATTGGG AGCGCCCTCA GAAACCCAAG GCACCAGTGG GGCATTTTTA CGAACCCCAG 
GCTCCCTCTG CTGAGGTGGA GATGACATCC TATGTGCTCC TCGCTTATCT CACGGCCCAG 
CCAGCCCCAA CCTCGGAGGA CCTGACCTCT GCAACCAACA TCGTGAAGTG GATCACGAAG 
CAGCAGAATG CCCAGGGCGG TTTCTCCTCC ACCCAGGACA CAGTGGTGGC TCTCCATGCT 
CTGTCCAAAT ATGGAGCAGC CACATTTACC AGGACTGGGA AGGCTGCACA GGTGACTATC 
CAGTCTTCAG GGACATTTTC CAGCAAATTC CAAGTGGACA ACAACAACCG CCTGTTACTG 
CAGCAGGTCT CATTGCCAGA GCTGCCTGGG GAATACAGCA TGAAAGTGAC AGGAGAAGGA 
TGTGTCTACC TCCAGACATC CTTGAAATAC AATATTCTCC CAGAAAAGGA AGAGTTCCCC 
TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA ACTTGTGATG AACCCAAAGC CCACACCAGC 
TTCCAAATCT CCCTAAGTGT CAGTTACACA GGGAGCCGCT CTGCCTCCAA CATGGCGATC 
GTTGATGTGA AGATGGTCTC TGGCTTCATT CCCCTGAAGC CAACAGTGAA AATGCTTGAA 
AGATCTAACC ATGTGAGCCG GACAGAAGTC AGCAGCAACC ATGTCTTGAT TTACCTTGAT 
AAGGTGTCAA ATCAGACACT GAGCTTGTTC TTCACGGTTC TGCAAGATGT CCCAGTAAGA 
GATCTGAAAC CAGCCATAGT GAAAGTCTAT GATTACTACG AGACGGATGA GTTTGCAATT 
GCTGAGTACA ATGCTCCTTG CAGCAAAGAT CTTGGAAATG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000005.2
CDS	381..4805
Translation	MGKNKLLHPSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDDEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAPCSKDLGNA

Target ORF information:

RefSeq Version	NM_000014.5
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000014.5

ORF Insert Sequence:

ATGGGGAAGA ACAAACTCCT TCATCCAAGT CTGGTTCTTC TCCTCTTGGT CCTCCTGCCC 
ACAGACGCCT CAGTCTCTGG AAAACCGCAG TATATGGTTC TGGTCCCCTC CCTGCTCCAC 
ACTGAGACCA CTGAGAAGGG CTGTGTCCTT CTGAGCTACC TGAATGAGAC AGTGACTGTA 
AGTGCTTCCT TGGAGTCTGT CAGGGGAAAC AGGAGCCTCT TCACTGACCT GGAGGCGGAG 
AATGACGTAC TCCACTGTGT CGCCTTCGCT GTCCCAAAGT CTTCATCCAA TGAGGAGGTA 
ATGTTCCTCA CTGTCCAAGT GAAAGGACCA ACCCAAGAAT TTAAGAAGCG GACCACAGTG 
ATGGTTAAGA ACGAGGACAG TCTGGTCTTT GTCCAGACAG ACAAATCAAT CTACAAACCA 
GGGCAGACAG TGAAATTTCG TGTTGTCTCC ATGGATGAAA ACTTTCACCC CCTGAATGAG 
TTGATTCCAC TAGTATACAT TCAGGATCCC AAAGGAAATC GCATCGCACA ATGGCAGAGT 
TTCCAGTTAG AGGGTGGCCT CAAGCAATTT TCTTTTCCCC TCTCATCAGA GCCCTTCCAG 
GGCTCCTACA AGGTGGTGGT ACAGAAGAAA TCAGGTGGAA GGACAGAGCA CCCTTTCACC 
GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA GTACAAGTAA CAGTGCCAAA GATAATCACC 
ATCTTGGAAG AAGAGATGAA TGTATCAGTG TGTGGCCTAT ACACATATGG GAAGCCTGTC 
CCTGGACATG TGACTGTGAG CATTTGCAGA AAGTATAGTG ACGCTTCCGA CTGCCACGGT 
GAAGATTCAC AGGCTTTCTG TGAGAAATTC AGTGGACAGC TAAACAGCCA TGGCTGCTTC 
TATCAGCAAG TAAAAACCAA GGTCTTCCAG CTGAAGAGGA AGGAGTATGA AATGAAACTT 
CACACTGAGG CCCAGATCCA AGAAGAAGGA ACAGTGGTGG AATTGACTGG AAGGCAGTCC 
AGTGAAATCA CAAGAACCAT AACCAAACTC TCATTTGTGA AAGTGGACTC ACACTTTCGA 
CAGGGAATTC CCTTCTTTGG GCAGGTGCGC CTAGTAGATG GGAAAGGCGT CCCTATACCA 
AATAAAGTCA TATTCATCAG AGGAAATGAA GCAAACTATT ACTCCAATGC TACCACGGAT 
GAGCATGGCC TTGTACAGTT CTCTATCAAC ACCACCAATG TTATGGGTAC CTCTCTTACT 
GTTAGGGTCA ATTACAAGGA TCGTAGTCCC TGTTACGGCT ACCAGTGGGT GTCAGAAGAA 
CACGAAGAGG CACATCACAC TGCTTATCTT GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC 
CTTGAGCCCA TGTCTCATGA ACTACCCTGT GGCCATACTC AGACAGTCCA GGCACATTAT 
ATTCTGAATG GAGGCACCCT GCTGGGGCTG AAGAAGCTCT CCTTCTATTA TCTGATAATG 
GCAAAGGGAG GCATTGTCCG AACTGGGACT CATGGACTGC TTGTGAAGCA GGAAGACATG 
AAGGGCCATT TTTCCATCTC AATCCCTGTG AAGTCAGACA TTGCTCCTGT CGCTCGGTTG 
CTCATCTATG CTGTTTTACC TACCGGGGAC GTGATTGGGG ATTCTGCAAA ATATGATGTT 
GAAAATTGTC TGGCCAACAA GGTGGATTTG AGCTTCAGCC CATCACAAAG TCTCCCAGCC 
TCACACGCCC ACCTGCGAGT CACAGCGGCT CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG 
GACCAAAGCG TGCTGCTCAT GAAGCCTGAT GCTGAGCTCT CGGCGTCCTC GGTTTACAAC 
CTGCTACCAG AAAAGGACCT CACTGGCTTC CCTGGGCCTT TGAATGACCA GGACGATGAA 
GACTGCATCA ATCGTCATAA TGTCTATATT AATGGAATCA CATATACTCC AGTATCAAGT 
ACAAATGAAA AGGATATGTA CAGCTTCCTA GAGGACATGG GCTTAAAGGC ATTCACCAAC 
TCAAAGATTC GTAAACCCAA AATGTGTCCA CAGCTTCAAC AGTATGAAAT GCATGGACCT 
GAAGGTCTAC GTGTAGGTTT TTATGAGTCA GATGTAATGG GAAGAGGCCA TGCACGCCTG 
GTGCATGTTG AAGAGCCTCA CACGGAGACC GTACGAAAGT ACTTCCCTGA GACATGGATC 
TGGGATTTGG TGGTGGTAAA CTCAGCAGGT GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC 
ACCATCACCG AGTGGAAGGC AGGGGCCTTC TGCCTGTCTG AAGATGCTGG ACTTGGTATC 
TCTTCCACTG CCTCTCTCCG AGCCTTCCAG CCCTTCTTTG TGGAGCTCAC AATGCCTTAC 
TCTGTGATTC GTGGAGAGGC CTTCACACTC AAGGCCACGG TCCTAAACTA CCTTCCCAAA 
TGCATCCGGG TCAGTGTGCA GCTGGAAGCC TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG 
AAGGAACAAG CGCCTCACTG CATCTGTGCA AACGGGCGGC AAACTGTGTC CTGGGCAGTA 
ACCCCAAAGT CATTAGGAAA TGTGAATTTC ACTGTGAGCG CAGAGGCACT AGAGTCTCAA 
GAGCTGTGTG GGACTGAGGT GCCTTCAGTT CCTGAACACG GAAGGAAAGA CACAGTCATC 
AAGCCTCTGT TGGTTGAACC TGAAGGACTA GAGAAGGAAA CAACATTCAA CTCCCTACTT 
TGTCCATCAG GTGGTGAGGT TTCTGAAGAA TTATCCCTGA AACTGCCACC AAATGTGGTA 
GAAGAATCTG CCCGAGCTTC TGTCTCAGTT TTGGGAGACA TATTAGGCTC TGCCATGCAA 
AACACACAAA ATCTTCTCCA GATGCCCTAT GGCTGTGGAG AGCAGAATAT GGTCCTCTTT 
GCTCCTAACA TCTATGTACT GGATTATCTA AATGAAACAC AGCAGCTTAC TCCAGAGATC 
AAGTCCAAGG CCATTGGCTA TCTCAACACT GGTTACCAGA GACAGTTGAA CTACAAACAC 
TATGATGGCT CCTACAGCAC CTTTGGGGAG CGATATGGCA GGAACCAGGG CAACACCTGG 
CTCACAGCCT TTGTTCTGAA GACTTTTGCC CAAGCTCGAG CCTACATCTT CATCGATGAA 
GCACACATTA CCCAAGCCCT CATATGGCTC TCCCAGAGGC AGAAGGACAA TGGCTGTTTC 
AGGAGCTCTG GGTCACTGCT CAACAATGCC ATAAAGGGAG GAGTAGAAGA TGAAGTGACC 
CTCTCCGCCT ATATCACCAT CGCCCTTCTG GAGATTCCTC TCACAGTCAC TCACCCTGTT 
GTCCGCAATG CCCTGTTTTG CCTGGAGTCA GCCTGGAAGA CAGCACAAGA AGGGGACCAT 
GGCAGCCATG TATATACCAA AGCACTGCTG GCCTATGCTT TTGCCCTGGC AGGTAACCAG 
GACAAGAGGA AGGAAGTACT CAAGTCACTT AATGAGGAAG CTGTGAAGAA AGACAACTCT 
GTCCATTGGG AGCGCCCTCA GAAACCCAAG GCACCAGTGG GGCATTTTTA CGAACCCCAG 
GCTCCCTCTG CTGAGGTGGA GATGACATCC TATGTGCTCC TCGCTTATCT CACGGCCCAG 
CCAGCCCCAA CCTCGGAGGA CCTGACCTCT GCAACCAACA TCGTGAAGTG GATCACGAAG 
CAGCAGAATG CCCAGGGCGG TTTCTCCTCC ACCCAGGACA CAGTGGTGGC TCTCCATGCT 
CTGTCCAAAT ATGGAGCAGC CACATTTACC AGGACTGGGA AGGCTGCACA GGTGACTATC 
CAGTCTTCAG GGACATTTTC CAGCAAATTC CAAGTGGACA ACAACAACCG CCTGTTACTG 
CAGCAGGTCT CATTGCCAGA GCTGCCTGGG GAATACAGCA TGAAAGTGAC AGGAGAAGGA 
TGTGTCTACC TCCAGACATC CTTGAAATAC AATATTCTCC CAGAAAAGGA AGAGTTCCCC 
TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA ACTTGTGATG AACCCAAAGC CCACACCAGC 
TTCCAAATCT CCCTAAGTGT CAGTTACACA GGGAGCCGCT CTGCCTCCAA CATGGCGATC 
GTTGATGTGA AGATGGTCTC TGGCTTCATT CCCCTGAAGC CAACAGTGAA AATGCTTGAA 
AGATCTAACC ATGTGAGCCG GACAGAAGTC AGCAGCAACC ATGTCTTGAT TTACCTTGAT 
AAGGTGTCAA ATCAGACACT GAGCTTGTTC TTCACGGTTC TGCAAGATGT CCCAGTAAGA 
GATCTGAAAC CAGCCATAGT GAAAGTCTAT GATTACTACG AGACGGATGA GTTTGCAATT 
GCTGAGTACA ATGCTCCTTG CAGCAAAGAT CTTGGAAATG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

A2M ( NM_001347424.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001334353.1 Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu102221
Clone ID Related Accession (Same CDS sequence)	NM_001347424.1
Accession Version	NM_001347424.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4125bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-27
Organism	Homo sapiens(human)
Product	alpha-2-macroglobulin isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC334781.1, DC402196.1, DB288732.1, AC007436.1, BC040071.1 and AB209614.2. Transcript Variant: This variant (3) contains an alternate splice site in the 5' region, and it thus differs in its 5' UTR and initiates translation from a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.221045.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTCCTCA CTGTCCAAGT GAAAGGACCA ACCCAAGAAT TTAAGAAGCG GACCACAGTG 
ATGGTTAAGA ACGAGGACAG TCTGGTCTTT GTCCAGACAG ACAAATCAAT CTACAAACCA 
GGGCAGACAG TGAAATTTCG TGTTGTCTCC ATGGATGAAA ACTTTCACCC CCTGAATGAG 
TTGATTCCAC TAGTATACAT TCAGGATCCC AAAGGAAATC GCATCGCACA ATGGCAGAGT 
TTCCAGTTAG AGGGTGGCCT CAAGCAATTT TCTTTTCCCC TCTCATCAGA GCCCTTCCAG 
GGCTCCTACA AGGTGGTGGT ACAGAAGAAA TCAGGTGGAA GGACAGAGCA CCCTTTCACC 
GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA GTACAAGTAA CAGTGCCAAA GATAATCACC 
ATCTTGGAAG AAGAGATGAA TGTATCAGTG TGTGGCCTAT ACACATATGG GAAGCCTGTC 
CCTGGACATG TGACTGTGAG CATTTGCAGA AAGTATAGTG ACGCTTCCGA CTGCCACGGT 
GAAGATTCAC AGGCTTTCTG TGAGAAATTC AGTGGACAGC TAAACAGCCA TGGCTGCTTC 
TATCAGCAAG TAAAAACCAA GGTCTTCCAG CTGAAGAGGA AGGAGTATGA AATGAAACTT 
CACACTGAGG CCCAGATCCA AGAAGAAGGA ACAGTGGTGG AATTGACTGG AAGGCAGTCC 
AGTGAAATCA CAAGAACCAT AACCAAACTC TCATTTGTGA AAGTGGACTC ACACTTTCGA 
CAGGGAATTC CCTTCTTTGG GCAGGTGCGC CTAGTAGATG GGAAAGGCGT CCCTATACCA 
AATAAAGTCA TATTCATCAG AGGAAATGAA GCAAACTATT ACTCCAATGC TACCACGGAT 
GAGCATGGCC TTGTACAGTT CTCTATCAAC ACCACCAATG TTATGGGTAC CTCTCTTACT 
GTTAGGGTCA ATTACAAGGA TCGTAGTCCC TGTTACGGCT ACCAGTGGGT GTCAGAAGAA 
CACGAAGAGG CACATCACAC TGCTTATCTT GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC 
CTTGAGCCCA TGTCTCATGA ACTACCCTGT GGCCATACTC AGACAGTCCA GGCACATTAT 
ATTCTGAATG GAGGCACCCT GCTGGGGCTG AAGAAGCTCT CCTTCTATTA TCTGATAATG 
GCAAAGGGAG GCATTGTCCG AACTGGGACT CATGGACTGC TTGTGAAGCA GGAAGACATG 
AAGGGCCATT TTTCCATCTC AATCCCTGTG AAGTCAGACA TTGCTCCTGT CGCTCGGTTG 
CTCATCTATG CTGTTTTACC TACCGGGGAC GTGATTGGGG ATTCTGCAAA ATATGATGTT 
GAAAATTGTC TGGCCAACAA GGTGGATTTG AGCTTCAGCC CATCACAAAG TCTCCCAGCC 
TCACACGCCC ACCTGCGAGT CACAGCGGCT CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG 
GACCAAAGCG TGCTGCTCAT GAAGCCTGAT GCTGAGCTCT CGGCGTCCTC GGTTTACAAC 
CTGCTACCAG AAAAGGACCT CACTGGCTTC CCTGGGCCTT TGAATGACCA GGACGATGAA 
GACTGCATCA ATCGTCATAA TGTCTATATT AATGGAATCA CATATACTCC AGTATCAAGT 
ACAAATGAAA AGGATATGTA CAGCTTCCTA GAGGACATGG GCTTAAAGGC ATTCACCAAC 
TCAAAGATTC GTAAACCCAA AATGTGTCCA CAGCTTCAAC AGTATGAAAT GCATGGACCT 
GAAGGTCTAC GTGTAGGTTT TTATGAGTCA GATGTAATGG GAAGAGGCCA TGCACGCCTG 
GTGCATGTTG AAGAGCCTCA CACGGAGACC GTACGAAAGT ACTTCCCTGA GACATGGATC 
TGGGATTTGG TGGTGGTAAA CTCAGCAGGT GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC 
ACCATCACCG AGTGGAAGGC AGGGGCCTTC TGCCTGTCTG AAGATGCTGG ACTTGGTATC 
TCTTCCACTG CCTCTCTCCG AGCCTTCCAG CCCTTCTTTG TGGAGCTCAC AATGCCTTAC 
TCTGTGATTC GTGGAGAGGC CTTCACACTC AAGGCCACGG TCCTAAACTA CCTTCCCAAA 
TGCATCCGGG TCAGTGTGCA GCTGGAAGCC TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG 
AAGGAACAAG CGCCTCACTG CATCTGTGCA AACGGGCGGC AAACTGTGTC CTGGGCAGTA 
ACCCCAAAGT CATTAGGAAA TGTGAATTTC ACTGTGAGCG CAGAGGCACT AGAGTCTCAA 
GAGCTGTGTG GGACTGAGGT GCCTTCAGTT CCTGAACACG GAAGGAAAGA CACAGTCATC 
AAGCCTCTGT TGGTTGAACC TGAAGGACTA GAGAAGGAAA CAACATTCAA CTCCCTACTT 
TGTCCATCAG GTGGTGAGGT TTCTGAAGAA TTATCCCTGA AACTGCCACC AAATGTGGTA 
GAAGAATCTG CCCGAGCTTC TGTCTCAGTT TTGGGAGACA TATTAGGCTC TGCCATGCAA 
AACACACAAA ATCTTCTCCA GATGCCCTAT GGCTGTGGAG AGCAGAATAT GGTCCTCTTT 
GCTCCTAACA TCTATGTACT GGATTATCTA AATGAAACAC AGCAGCTTAC TCCAGAGATC 
AAGTCCAAGG CCATTGGCTA TCTCAACACT GGTTACCAGA GACAGTTGAA CTACAAACAC 
TATGATGGCT CCTACAGCAC CTTTGGGGAG CGATATGGCA GGAACCAGGG CAACACCTGG 
CTCACAGCCT TTGTTCTGAA GACTTTTGCC CAAGCTCGAG CCTACATCTT CATCGATGAA 
GCACACATTA CCCAAGCCCT CATATGGCTC TCCCAGAGGC AGAAGGACAA TGGCTGTTTC 
AGGAGCTCTG GGTCACTGCT CAACAATGCC ATAAAGGGAG GAGTAGAAGA TGAAGTGACC 
CTCTCCGCCT ATATCACCAT CGCCCTTCTG GAGATTCCTC TCACAGTCAC TCACCCTGTT 
GTCCGCAATG CCCTGTTTTG CCTGGAGTCA GCCTGGAAGA CAGCACAAGA AGGGGACCAT 
GGCAGCCATG TATATACCAA AGCACTGCTG GCCTATGCTT TTGCCCTGGC AGGTAACCAG 
GACAAGAGGA AGGAAGTACT CAAGTCACTT AATGAGGAAG CTGTGAAGAA AGACAACTCT 
GTCCATTGGG AGCGCCCTCA GAAACCCAAG GCACCAGTGG GGCATTTTTA CGAACCCCAG 
GCTCCCTCTG CTGAGGTGGA GATGACATCC TATGTGCTCC TCGCTTATCT CACGGCCCAG 
CCAGCCCCAA CCTCGGAGGA CCTGACCTCT GCAACCAACA TCGTGAAGTG GATCACGAAG 
CAGCAGAATG CCCAGGGCGG TTTCTCCTCC ACCCAGGACA CAGTGGTGGC TCTCCATGCT 
CTGTCCAAAT ATGGAGCAGC CACATTTACC AGGACTGGGA AGGCTGCACA GGTGACTATC 
CAGTCTTCAG GGACATTTTC CAGCAAATTC CAAGTGGACA ACAACAACCG CCTGTTACTG 
CAGCAGGTCT CATTGCCAGA GCTGCCTGGG GAATACAGCA TGAAAGTGAC AGGAGAAGGA 
TGTGTCTACC TCCAGACATC CTTGAAATAC AATATTCTCC CAGAAAAGGA AGAGTTCCCC 
TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA ACTTGTGATG AACCCAAAGC CCACACCAGC 
TTCCAAATCT CCCTAAGTGT CAGTTACACA GGGAGCCGCT CTGCCTCCAA CATGGCGATC 
GTTGATGTGA AGATGGTCTC TGGCTTCATT CCCCTGAAGC CAACAGTGAA AATGCTTGAA 
AGATCTAACC ATGTGAGCCG GACAGAAGTC AGCAGCAACC ATGTCTTGAT TTACCTTGAT 
AAGGTGTCAA ATCAGACACT GAGCTTGTTC TTCACGGTTC TGCAAGATGT CCCAGTAAGA 
GATCTGAAAC CAGCCATAGT GAAAGTCTAT GATTACTACG AGACGGATGA GTTTGCAATT 
GCTGAGTACA ATGCTCCTTG CAGCAAAGAT CTTGGAAATG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001334353.1
CDS	834..4958
Translation	MFLTVQVKGPTQEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDDEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAPCSKDLGNA

Target ORF information:

RefSeq Version	NM_001347424.1
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001347424.1

ORF Insert Sequence:

ATGTTCCTCA CTGTCCAAGT GAAAGGACCA ACCCAAGAAT TTAAGAAGCG GACCACAGTG 
ATGGTTAAGA ACGAGGACAG TCTGGTCTTT GTCCAGACAG ACAAATCAAT CTACAAACCA 
GGGCAGACAG TGAAATTTCG TGTTGTCTCC ATGGATGAAA ACTTTCACCC CCTGAATGAG 
TTGATTCCAC TAGTATACAT TCAGGATCCC AAAGGAAATC GCATCGCACA ATGGCAGAGT 
TTCCAGTTAG AGGGTGGCCT CAAGCAATTT TCTTTTCCCC TCTCATCAGA GCCCTTCCAG 
GGCTCCTACA AGGTGGTGGT ACAGAAGAAA TCAGGTGGAA GGACAGAGCA CCCTTTCACC 
GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA GTACAAGTAA CAGTGCCAAA GATAATCACC 
ATCTTGGAAG AAGAGATGAA TGTATCAGTG TGTGGCCTAT ACACATATGG GAAGCCTGTC 
CCTGGACATG TGACTGTGAG CATTTGCAGA AAGTATAGTG ACGCTTCCGA CTGCCACGGT 
GAAGATTCAC AGGCTTTCTG TGAGAAATTC AGTGGACAGC TAAACAGCCA TGGCTGCTTC 
TATCAGCAAG TAAAAACCAA GGTCTTCCAG CTGAAGAGGA AGGAGTATGA AATGAAACTT 
CACACTGAGG CCCAGATCCA AGAAGAAGGA ACAGTGGTGG AATTGACTGG AAGGCAGTCC 
AGTGAAATCA CAAGAACCAT AACCAAACTC TCATTTGTGA AAGTGGACTC ACACTTTCGA 
CAGGGAATTC CCTTCTTTGG GCAGGTGCGC CTAGTAGATG GGAAAGGCGT CCCTATACCA 
AATAAAGTCA TATTCATCAG AGGAAATGAA GCAAACTATT ACTCCAATGC TACCACGGAT 
GAGCATGGCC TTGTACAGTT CTCTATCAAC ACCACCAATG TTATGGGTAC CTCTCTTACT 
GTTAGGGTCA ATTACAAGGA TCGTAGTCCC TGTTACGGCT ACCAGTGGGT GTCAGAAGAA 
CACGAAGAGG CACATCACAC TGCTTATCTT GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC 
CTTGAGCCCA TGTCTCATGA ACTACCCTGT GGCCATACTC AGACAGTCCA GGCACATTAT 
ATTCTGAATG GAGGCACCCT GCTGGGGCTG AAGAAGCTCT CCTTCTATTA TCTGATAATG 
GCAAAGGGAG GCATTGTCCG AACTGGGACT CATGGACTGC TTGTGAAGCA GGAAGACATG 
AAGGGCCATT TTTCCATCTC AATCCCTGTG AAGTCAGACA TTGCTCCTGT CGCTCGGTTG 
CTCATCTATG CTGTTTTACC TACCGGGGAC GTGATTGGGG ATTCTGCAAA ATATGATGTT 
GAAAATTGTC TGGCCAACAA GGTGGATTTG AGCTTCAGCC CATCACAAAG TCTCCCAGCC 
TCACACGCCC ACCTGCGAGT CACAGCGGCT CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG 
GACCAAAGCG TGCTGCTCAT GAAGCCTGAT GCTGAGCTCT CGGCGTCCTC GGTTTACAAC 
CTGCTACCAG AAAAGGACCT CACTGGCTTC CCTGGGCCTT TGAATGACCA GGACGATGAA 
GACTGCATCA ATCGTCATAA TGTCTATATT AATGGAATCA CATATACTCC AGTATCAAGT 
ACAAATGAAA AGGATATGTA CAGCTTCCTA GAGGACATGG GCTTAAAGGC ATTCACCAAC 
TCAAAGATTC GTAAACCCAA AATGTGTCCA CAGCTTCAAC AGTATGAAAT GCATGGACCT 
GAAGGTCTAC GTGTAGGTTT TTATGAGTCA GATGTAATGG GAAGAGGCCA TGCACGCCTG 
GTGCATGTTG AAGAGCCTCA CACGGAGACC GTACGAAAGT ACTTCCCTGA GACATGGATC 
TGGGATTTGG TGGTGGTAAA CTCAGCAGGT GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC 
ACCATCACCG AGTGGAAGGC AGGGGCCTTC TGCCTGTCTG AAGATGCTGG ACTTGGTATC 
TCTTCCACTG CCTCTCTCCG AGCCTTCCAG CCCTTCTTTG TGGAGCTCAC AATGCCTTAC 
TCTGTGATTC GTGGAGAGGC CTTCACACTC AAGGCCACGG TCCTAAACTA CCTTCCCAAA 
TGCATCCGGG TCAGTGTGCA GCTGGAAGCC TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG 
AAGGAACAAG CGCCTCACTG CATCTGTGCA AACGGGCGGC AAACTGTGTC CTGGGCAGTA 
ACCCCAAAGT CATTAGGAAA TGTGAATTTC ACTGTGAGCG CAGAGGCACT AGAGTCTCAA 
GAGCTGTGTG GGACTGAGGT GCCTTCAGTT CCTGAACACG GAAGGAAAGA CACAGTCATC 
AAGCCTCTGT TGGTTGAACC TGAAGGACTA GAGAAGGAAA CAACATTCAA CTCCCTACTT 
TGTCCATCAG GTGGTGAGGT TTCTGAAGAA TTATCCCTGA AACTGCCACC AAATGTGGTA 
GAAGAATCTG CCCGAGCTTC TGTCTCAGTT TTGGGAGACA TATTAGGCTC TGCCATGCAA 
AACACACAAA ATCTTCTCCA GATGCCCTAT GGCTGTGGAG AGCAGAATAT GGTCCTCTTT 
GCTCCTAACA TCTATGTACT GGATTATCTA AATGAAACAC AGCAGCTTAC TCCAGAGATC 
AAGTCCAAGG CCATTGGCTA TCTCAACACT GGTTACCAGA GACAGTTGAA CTACAAACAC 
TATGATGGCT CCTACAGCAC CTTTGGGGAG CGATATGGCA GGAACCAGGG CAACACCTGG 
CTCACAGCCT TTGTTCTGAA GACTTTTGCC CAAGCTCGAG CCTACATCTT CATCGATGAA 
GCACACATTA CCCAAGCCCT CATATGGCTC TCCCAGAGGC AGAAGGACAA TGGCTGTTTC 
AGGAGCTCTG GGTCACTGCT CAACAATGCC ATAAAGGGAG GAGTAGAAGA TGAAGTGACC 
CTCTCCGCCT ATATCACCAT CGCCCTTCTG GAGATTCCTC TCACAGTCAC TCACCCTGTT 
GTCCGCAATG CCCTGTTTTG CCTGGAGTCA GCCTGGAAGA CAGCACAAGA AGGGGACCAT 
GGCAGCCATG TATATACCAA AGCACTGCTG GCCTATGCTT TTGCCCTGGC AGGTAACCAG 
GACAAGAGGA AGGAAGTACT CAAGTCACTT AATGAGGAAG CTGTGAAGAA AGACAACTCT 
GTCCATTGGG AGCGCCCTCA GAAACCCAAG GCACCAGTGG GGCATTTTTA CGAACCCCAG 
GCTCCCTCTG CTGAGGTGGA GATGACATCC TATGTGCTCC TCGCTTATCT CACGGCCCAG 
CCAGCCCCAA CCTCGGAGGA CCTGACCTCT GCAACCAACA TCGTGAAGTG GATCACGAAG 
CAGCAGAATG CCCAGGGCGG TTTCTCCTCC ACCCAGGACA CAGTGGTGGC TCTCCATGCT 
CTGTCCAAAT ATGGAGCAGC CACATTTACC AGGACTGGGA AGGCTGCACA GGTGACTATC 
CAGTCTTCAG GGACATTTTC CAGCAAATTC CAAGTGGACA ACAACAACCG CCTGTTACTG 
CAGCAGGTCT CATTGCCAGA GCTGCCTGGG GAATACAGCA TGAAAGTGAC AGGAGAAGGA 
TGTGTCTACC TCCAGACATC CTTGAAATAC AATATTCTCC CAGAAAAGGA AGAGTTCCCC 
TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA ACTTGTGATG AACCCAAAGC CCACACCAGC 
TTCCAAATCT CCCTAAGTGT CAGTTACACA GGGAGCCGCT CTGCCTCCAA CATGGCGATC 
GTTGATGTGA AGATGGTCTC TGGCTTCATT CCCCTGAAGC CAACAGTGAA AATGCTTGAA 
AGATCTAACC ATGTGAGCCG GACAGAAGTC AGCAGCAACC ATGTCTTGAT TTACCTTGAT 
AAGGTGTCAA ATCAGACACT GAGCTTGTTC TTCACGGTTC TGCAAGATGT CCCAGTAAGA 
GATCTGAAAC CAGCCATAGT GAAAGTCTAT GATTACTACG AGACGGATGA GTTTGCAATT 
GCTGAGTACA ATGCTCCTTG CAGCAAAGAT CTTGGAAATG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

A2M ( NM_001347425.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001334354.1 Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 4, mRNA.

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CloneID	OHu102390
Clone ID Related Accession (Same CDS sequence)	NM_001347425.1
Accession Version	NM_001347425.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3975bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-27
Organism	Homo sapiens(human)
Product	alpha-2-macroglobulin isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC334781.1, DC402196.1, AK307832.1 and BC040071.1. Transcript Variant: This variant (4) lacks an exon in the 5' region, and it thus differs in its 5' UTR and initiates translation from a downstream in-frame start codon, compared to variant 1. The encoded isoform (c) is shorter at the N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.96034.1, AK307832.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATGAAA ACTTTCACCC CCTGAATGAG TTGATTCCAC TAGTATACAT TCAGGATCCC 
AAAGGAAATC GCATCGCACA ATGGCAGAGT TTCCAGTTAG AGGGTGGCCT CAAGCAATTT 
TCTTTTCCCC TCTCATCAGA GCCCTTCCAG GGCTCCTACA AGGTGGTGGT ACAGAAGAAA 
TCAGGTGGAA GGACAGAGCA CCCTTTCACC GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA 
GTACAAGTAA CAGTGCCAAA GATAATCACC ATCTTGGAAG AAGAGATGAA TGTATCAGTG 
TGTGGCCTAT ACACATATGG GAAGCCTGTC CCTGGACATG TGACTGTGAG CATTTGCAGA 
AAGTATAGTG ACGCTTCCGA CTGCCACGGT GAAGATTCAC AGGCTTTCTG TGAGAAATTC 
AGTGGACAGC TAAACAGCCA TGGCTGCTTC TATCAGCAAG TAAAAACCAA GGTCTTCCAG 
CTGAAGAGGA AGGAGTATGA AATGAAACTT CACACTGAGG CCCAGATCCA AGAAGAAGGA 
ACAGTGGTGG AATTGACTGG AAGGCAGTCC AGTGAAATCA CAAGAACCAT AACCAAACTC 
TCATTTGTGA AAGTGGACTC ACACTTTCGA CAGGGAATTC CCTTCTTTGG GCAGGTGCGC 
CTAGTAGATG GGAAAGGCGT CCCTATACCA AATAAAGTCA TATTCATCAG AGGAAATGAA 
GCAAACTATT ACTCCAATGC TACCACGGAT GAGCATGGCC TTGTACAGTT CTCTATCAAC 
ACCACCAATG TTATGGGTAC CTCTCTTACT GTTAGGGTCA ATTACAAGGA TCGTAGTCCC 
TGTTACGGCT ACCAGTGGGT GTCAGAAGAA CACGAAGAGG CACATCACAC TGCTTATCTT 
GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC CTTGAGCCCA TGTCTCATGA ACTACCCTGT 
GGCCATACTC AGACAGTCCA GGCACATTAT ATTCTGAATG GAGGCACCCT GCTGGGGCTG 
AAGAAGCTCT CCTTCTATTA TCTGATAATG GCAAAGGGAG GCATTGTCCG AACTGGGACT 
CATGGACTGC TTGTGAAGCA GGAAGACATG AAGGGCCATT TTTCCATCTC AATCCCTGTG 
AAGTCAGACA TTGCTCCTGT CGCTCGGTTG CTCATCTATG CTGTTTTACC TACCGGGGAC 
GTGATTGGGG ATTCTGCAAA ATATGATGTT GAAAATTGTC TGGCCAACAA GGTGGATTTG 
AGCTTCAGCC CATCACAAAG TCTCCCAGCC TCACACGCCC ACCTGCGAGT CACAGCGGCT 
CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG GACCAAAGCG TGCTGCTCAT GAAGCCTGAT 
GCTGAGCTCT CGGCGTCCTC GGTTTACAAC CTGCTACCAG AAAAGGACCT CACTGGCTTC 
CCTGGGCCTT TGAATGACCA GGACGATGAA GACTGCATCA ATCGTCATAA TGTCTATATT 
AATGGAATCA CATATACTCC AGTATCAAGT ACAAATGAAA AGGATATGTA CAGCTTCCTA 
GAGGACATGG GCTTAAAGGC ATTCACCAAC TCAAAGATTC GTAAACCCAA AATGTGTCCA 
CAGCTTCAAC AGTATGAAAT GCATGGACCT GAAGGTCTAC GTGTAGGTTT TTATGAGTCA 
GATGTAATGG GAAGAGGCCA TGCACGCCTG GTGCATGTTG AAGAGCCTCA CACGGAGACC 
GTACGAAAGT ACTTCCCTGA GACATGGATC TGGGATTTGG TGGTGGTAAA CTCAGCAGGT 
GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC ACCATCACCG AGTGGAAGGC AGGGGCCTTC 
TGCCTGTCTG AAGATGCTGG ACTTGGTATC TCTTCCACTG CCTCTCTCCG AGCCTTCCAG 
CCCTTCTTTG TGGAGCTCAC AATGCCTTAC TCTGTGATTC GTGGAGAGGC CTTCACACTC 
AAGGCCACGG TCCTAAACTA CCTTCCCAAA TGCATCCGGG TCAGTGTGCA GCTGGAAGCC 
TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG AAGGAACAAG CGCCTCACTG CATCTGTGCA 
AACGGGCGGC AAACTGTGTC CTGGGCAGTA ACCCCAAAGT CATTAGGAAA TGTGAATTTC 
ACTGTGAGCG CAGAGGCACT AGAGTCTCAA GAGCTGTGTG GGACTGAGGT GCCTTCAGTT 
CCTGAACACG GAAGGAAAGA CACAGTCATC AAGCCTCTGT TGGTTGAACC TGAAGGACTA 
GAGAAGGAAA CAACATTCAA CTCCCTACTT TGTCCATCAG GTGGTGAGGT TTCTGAAGAA 
TTATCCCTGA AACTGCCACC AAATGTGGTA GAAGAATCTG CCCGAGCTTC TGTCTCAGTT 
TTGGGAGACA TATTAGGCTC TGCCATGCAA AACACACAAA ATCTTCTCCA GATGCCCTAT 
GGCTGTGGAG AGCAGAATAT GGTCCTCTTT GCTCCTAACA TCTATGTACT GGATTATCTA 
AATGAAACAC AGCAGCTTAC TCCAGAGATC AAGTCCAAGG CCATTGGCTA TCTCAACACT 
GGTTACCAGA GACAGTTGAA CTACAAACAC TATGATGGCT CCTACAGCAC CTTTGGGGAG 
CGATATGGCA GGAACCAGGG CAACACCTGG CTCACAGCCT TTGTTCTGAA GACTTTTGCC 
CAAGCTCGAG CCTACATCTT CATCGATGAA GCACACATTA CCCAAGCCCT CATATGGCTC 
TCCCAGAGGC AGAAGGACAA TGGCTGTTTC AGGAGCTCTG GGTCACTGCT CAACAATGCC 
ATAAAGGGAG GAGTAGAAGA TGAAGTGACC CTCTCCGCCT ATATCACCAT CGCCCTTCTG 
GAGATTCCTC TCACAGTCAC TCACCCTGTT GTCCGCAATG CCCTGTTTTG CCTGGAGTCA 
GCCTGGAAGA CAGCACAAGA AGGGGACCAT GGCAGCCATG TATATACCAA AGCACTGCTG 
GCCTATGCTT TTGCCCTGGC AGGTAACCAG GACAAGAGGA AGGAAGTACT CAAGTCACTT 
AATGAGGAAG CTGTGAAGAA AGACAACTCT GTCCATTGGG AGCGCCCTCA GAAACCCAAG 
GCACCAGTGG GGCATTTTTA CGAACCCCAG GCTCCCTCTG CTGAGGTGGA GATGACATCC 
TATGTGCTCC TCGCTTATCT CACGGCCCAG CCAGCCCCAA CCTCGGAGGA CCTGACCTCT 
GCAACCAACA TCGTGAAGTG GATCACGAAG CAGCAGAATG CCCAGGGCGG TTTCTCCTCC 
ACCCAGGACA CAGTGGTGGC TCTCCATGCT CTGTCCAAAT ATGGAGCAGC CACATTTACC 
AGGACTGGGA AGGCTGCACA GGTGACTATC CAGTCTTCAG GGACATTTTC CAGCAAATTC 
CAAGTGGACA ACAACAACCG CCTGTTACTG CAGCAGGTCT CATTGCCAGA GCTGCCTGGG 
GAATACAGCA TGAAAGTGAC AGGAGAAGGA TGTGTCTACC TCCAGACATC CTTGAAATAC 
AATATTCTCC CAGAAAAGGA AGAGTTCCCC TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA 
ACTTGTGATG AACCCAAAGC CCACACCAGC TTCCAAATCT CCCTAAGTGT CAGTTACACA 
GGGAGCCGCT CTGCCTCCAA CATGGCGATC GTTGATGTGA AGATGGTCTC TGGCTTCATT 
CCCCTGAAGC CAACAGTGAA AATGCTTGAA AGATCTAACC ATGTGAGCCG GACAGAAGTC 
AGCAGCAACC ATGTCTTGAT TTACCTTGAT AAGGTGTCAA ATCAGACACT GAGCTTGTTC 
TTCACGGTTC TGCAAGATGT CCCAGTAAGA GATCTGAAAC CAGCCATAGT GAAAGTCTAT 
GATTACTACG AGACGGATGA GTTTGCAATT GCTGAGTACA ATGCTCCTTG CAGCAAAGAT 
CTTGGAAATG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001334354.1
CDS	671..4645
Translation	MDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDDEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAPCSKDLGNA

Target ORF information:

RefSeq Version	NM_001347425.1
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001347425.1

ORF Insert Sequence:

ATGGATGAAA ACTTTCACCC CCTGAATGAG TTGATTCCAC TAGTATACAT TCAGGATCCC 
AAAGGAAATC GCATCGCACA ATGGCAGAGT TTCCAGTTAG AGGGTGGCCT CAAGCAATTT 
TCTTTTCCCC TCTCATCAGA GCCCTTCCAG GGCTCCTACA AGGTGGTGGT ACAGAAGAAA 
TCAGGTGGAA GGACAGAGCA CCCTTTCACC GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA 
GTACAAGTAA CAGTGCCAAA GATAATCACC ATCTTGGAAG AAGAGATGAA TGTATCAGTG 
TGTGGCCTAT ACACATATGG GAAGCCTGTC CCTGGACATG TGACTGTGAG CATTTGCAGA 
AAGTATAGTG ACGCTTCCGA CTGCCACGGT GAAGATTCAC AGGCTTTCTG TGAGAAATTC 
AGTGGACAGC TAAACAGCCA TGGCTGCTTC TATCAGCAAG TAAAAACCAA GGTCTTCCAG 
CTGAAGAGGA AGGAGTATGA AATGAAACTT CACACTGAGG CCCAGATCCA AGAAGAAGGA 
ACAGTGGTGG AATTGACTGG AAGGCAGTCC AGTGAAATCA CAAGAACCAT AACCAAACTC 
TCATTTGTGA AAGTGGACTC ACACTTTCGA CAGGGAATTC CCTTCTTTGG GCAGGTGCGC 
CTAGTAGATG GGAAAGGCGT CCCTATACCA AATAAAGTCA TATTCATCAG AGGAAATGAA 
GCAAACTATT ACTCCAATGC TACCACGGAT GAGCATGGCC TTGTACAGTT CTCTATCAAC 
ACCACCAATG TTATGGGTAC CTCTCTTACT GTTAGGGTCA ATTACAAGGA TCGTAGTCCC 
TGTTACGGCT ACCAGTGGGT GTCAGAAGAA CACGAAGAGG CACATCACAC TGCTTATCTT 
GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC CTTGAGCCCA TGTCTCATGA ACTACCCTGT 
GGCCATACTC AGACAGTCCA GGCACATTAT ATTCTGAATG GAGGCACCCT GCTGGGGCTG 
AAGAAGCTCT CCTTCTATTA TCTGATAATG GCAAAGGGAG GCATTGTCCG AACTGGGACT 
CATGGACTGC TTGTGAAGCA GGAAGACATG AAGGGCCATT TTTCCATCTC AATCCCTGTG 
AAGTCAGACA TTGCTCCTGT CGCTCGGTTG CTCATCTATG CTGTTTTACC TACCGGGGAC 
GTGATTGGGG ATTCTGCAAA ATATGATGTT GAAAATTGTC TGGCCAACAA GGTGGATTTG 
AGCTTCAGCC CATCACAAAG TCTCCCAGCC TCACACGCCC ACCTGCGAGT CACAGCGGCT 
CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG GACCAAAGCG TGCTGCTCAT GAAGCCTGAT 
GCTGAGCTCT CGGCGTCCTC GGTTTACAAC CTGCTACCAG AAAAGGACCT CACTGGCTTC 
CCTGGGCCTT TGAATGACCA GGACGATGAA GACTGCATCA ATCGTCATAA TGTCTATATT 
AATGGAATCA CATATACTCC AGTATCAAGT ACAAATGAAA AGGATATGTA CAGCTTCCTA 
GAGGACATGG GCTTAAAGGC ATTCACCAAC TCAAAGATTC GTAAACCCAA AATGTGTCCA 
CAGCTTCAAC AGTATGAAAT GCATGGACCT GAAGGTCTAC GTGTAGGTTT TTATGAGTCA 
GATGTAATGG GAAGAGGCCA TGCACGCCTG GTGCATGTTG AAGAGCCTCA CACGGAGACC 
GTACGAAAGT ACTTCCCTGA GACATGGATC TGGGATTTGG TGGTGGTAAA CTCAGCAGGT 
GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC ACCATCACCG AGTGGAAGGC AGGGGCCTTC 
TGCCTGTCTG AAGATGCTGG ACTTGGTATC TCTTCCACTG CCTCTCTCCG AGCCTTCCAG 
CCCTTCTTTG TGGAGCTCAC AATGCCTTAC TCTGTGATTC GTGGAGAGGC CTTCACACTC 
AAGGCCACGG TCCTAAACTA CCTTCCCAAA TGCATCCGGG TCAGTGTGCA GCTGGAAGCC 
TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG AAGGAACAAG CGCCTCACTG CATCTGTGCA 
AACGGGCGGC AAACTGTGTC CTGGGCAGTA ACCCCAAAGT CATTAGGAAA TGTGAATTTC 
ACTGTGAGCG CAGAGGCACT AGAGTCTCAA GAGCTGTGTG GGACTGAGGT GCCTTCAGTT 
CCTGAACACG GAAGGAAAGA CACAGTCATC AAGCCTCTGT TGGTTGAACC TGAAGGACTA 
GAGAAGGAAA CAACATTCAA CTCCCTACTT TGTCCATCAG GTGGTGAGGT TTCTGAAGAA 
TTATCCCTGA AACTGCCACC AAATGTGGTA GAAGAATCTG CCCGAGCTTC TGTCTCAGTT 
TTGGGAGACA TATTAGGCTC TGCCATGCAA AACACACAAA ATCTTCTCCA GATGCCCTAT 
GGCTGTGGAG AGCAGAATAT GGTCCTCTTT GCTCCTAACA TCTATGTACT GGATTATCTA 
AATGAAACAC AGCAGCTTAC TCCAGAGATC AAGTCCAAGG CCATTGGCTA TCTCAACACT 
GGTTACCAGA GACAGTTGAA CTACAAACAC TATGATGGCT CCTACAGCAC CTTTGGGGAG 
CGATATGGCA GGAACCAGGG CAACACCTGG CTCACAGCCT TTGTTCTGAA GACTTTTGCC 
CAAGCTCGAG CCTACATCTT CATCGATGAA GCACACATTA CCCAAGCCCT CATATGGCTC 
TCCCAGAGGC AGAAGGACAA TGGCTGTTTC AGGAGCTCTG GGTCACTGCT CAACAATGCC 
ATAAAGGGAG GAGTAGAAGA TGAAGTGACC CTCTCCGCCT ATATCACCAT CGCCCTTCTG 
GAGATTCCTC TCACAGTCAC TCACCCTGTT GTCCGCAATG CCCTGTTTTG CCTGGAGTCA 
GCCTGGAAGA CAGCACAAGA AGGGGACCAT GGCAGCCATG TATATACCAA AGCACTGCTG 
GCCTATGCTT TTGCCCTGGC AGGTAACCAG GACAAGAGGA AGGAAGTACT CAAGTCACTT 
AATGAGGAAG CTGTGAAGAA AGACAACTCT GTCCATTGGG AGCGCCCTCA GAAACCCAAG 
GCACCAGTGG GGCATTTTTA CGAACCCCAG GCTCCCTCTG CTGAGGTGGA GATGACATCC 
TATGTGCTCC TCGCTTATCT CACGGCCCAG CCAGCCCCAA CCTCGGAGGA CCTGACCTCT 
GCAACCAACA TCGTGAAGTG GATCACGAAG CAGCAGAATG CCCAGGGCGG TTTCTCCTCC 
ACCCAGGACA CAGTGGTGGC TCTCCATGCT CTGTCCAAAT ATGGAGCAGC CACATTTACC 
AGGACTGGGA AGGCTGCACA GGTGACTATC CAGTCTTCAG GGACATTTTC CAGCAAATTC 
CAAGTGGACA ACAACAACCG CCTGTTACTG CAGCAGGTCT CATTGCCAGA GCTGCCTGGG 
GAATACAGCA TGAAAGTGAC AGGAGAAGGA TGTGTCTACC TCCAGACATC CTTGAAATAC 
AATATTCTCC CAGAAAAGGA AGAGTTCCCC TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA 
ACTTGTGATG AACCCAAAGC CCACACCAGC TTCCAAATCT CCCTAAGTGT CAGTTACACA 
GGGAGCCGCT CTGCCTCCAA CATGGCGATC GTTGATGTGA AGATGGTCTC TGGCTTCATT 
CCCCTGAAGC CAACAGTGAA AATGCTTGAA AGATCTAACC ATGTGAGCCG GACAGAAGTC 
AGCAGCAACC ATGTCTTGAT TTACCTTGAT AAGGTGTCAA ATCAGACACT GAGCTTGTTC 
TTCACGGTTC TGCAAGATGT CCCAGTAAGA GATCTGAAAC CAGCCATAGT GAAAGTCTAT 
GATTACTACG AGACGGATGA GTTTGCAATT GCTGAGTACA ATGCTCCTTG CAGCAAAGAT 
CTTGGAAATG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

A2M ( NM_001347423.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001334352.2 Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 2, mRNA.

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CloneID	OHu108400
Clone ID Related Accession (Same CDS sequence)	NM_001347423.2 , NM_000014.6
Accession Version	NM_001347423.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4425bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-02
Organism	Homo sapiens(human)
Product	alpha-2-macroglobulin isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC007436.1. On Jun 2, 2019 this sequence version replaced NM_001347423.1. Transcript Variant: This variant (2) splices out a region of the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.140912.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGAAGA ACAAACTCCT TCATCCAAGT CTGGTTCTTC TCCTCTTGGT CCTCCTGCCC 
ACAGACGCCT CAGTCTCTGG AAAACCGCAG TATATGGTTC TGGTCCCCTC CCTGCTCCAC 
ACTGAGACCA CTGAGAAGGG CTGTGTCCTT CTGAGCTACC TGAATGAGAC AGTGACTGTA 
AGTGCTTCCT TGGAGTCTGT CAGGGGAAAC AGGAGCCTCT TCACTGACCT GGAGGCGGAG 
AATGACGTAC TCCACTGTGT CGCCTTCGCT GTCCCAAAGT CTTCATCCAA TGAGGAGGTA 
ATGTTCCTCA CTGTCCAAGT GAAAGGACCA ACCCAAGAAT TTAAGAAGCG GACCACAGTG 
ATGGTTAAGA ACGAGGACAG TCTGGTCTTT GTCCAGACAG ACAAATCAAT CTACAAACCA 
GGGCAGACAG TGAAATTTCG TGTTGTCTCC ATGGATGAAA ACTTTCACCC CCTGAATGAG 
TTGATTCCAC TAGTATACAT TCAGGATCCC AAAGGAAATC GCATCGCACA ATGGCAGAGT 
TTCCAGTTAG AGGGTGGCCT CAAGCAATTT TCTTTTCCCC TCTCATCAGA GCCCTTCCAG 
GGCTCCTACA AGGTGGTGGT ACAGAAGAAA TCAGGTGGAA GGACAGAGCA CCCTTTCACC 
GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA GTACAAGTAA CAGTGCCAAA GATAATCACC 
ATCTTGGAAG AAGAGATGAA TGTATCAGTG TGTGGCCTAT ACACATATGG GAAGCCTGTC 
CCTGGACATG TGACTGTGAG CATTTGCAGA AAGTATAGTG ACGCTTCCGA CTGCCACGGT 
GAAGATTCAC AGGCTTTCTG TGAGAAATTC AGTGGACAGC TAAACAGCCA TGGCTGCTTC 
TATCAGCAAG TAAAAACCAA GGTCTTCCAG CTGAAGAGGA AGGAGTATGA AATGAAACTT 
CACACTGAGG CCCAGATCCA AGAAGAAGGA ACAGTGGTGG AATTGACTGG AAGGCAGTCC 
AGTGAAATCA CAAGAACCAT AACCAAACTC TCATTTGTGA AAGTGGACTC ACACTTTCGA 
CAGGGAATTC CCTTCTTTGG GCAGGTGCGC CTAGTAGATG GGAAAGGCGT CCCTATACCA 
AATAAAGTCA TATTCATCAG AGGAAATGAA GCAAACTATT ACTCCAATGC TACCACGGAT 
GAGCATGGCC TTGTACAGTT CTCTATCAAC ACCACCAATG TTATGGGTAC CTCTCTTACT 
GTTAGGGTCA ATTACAAGGA TCGTAGTCCC TGTTACGGCT ACCAGTGGGT GTCAGAAGAA 
CACGAAGAGG CACATCACAC TGCTTATCTT GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC 
CTTGAGCCCA TGTCTCATGA ACTACCCTGT GGCCATACTC AGACAGTCCA GGCACATTAT 
ATTCTGAATG GAGGCACCCT GCTGGGGCTG AAGAAGCTCT CCTTCTATTA TCTGATAATG 
GCAAAGGGAG GCATTGTCCG AACTGGGACT CATGGACTGC TTGTGAAGCA GGAAGACATG 
AAGGGCCATT TTTCCATCTC AATCCCTGTG AAGTCAGACA TTGCTCCTGT CGCTCGGTTG 
CTCATCTATG CTGTTTTACC TACCGGGGAC GTGATTGGGG ATTCTGCAAA ATATGATGTT 
GAAAATTGTC TGGCCAACAA GGTGGATTTG AGCTTCAGCC CATCACAAAG TCTCCCAGCC 
TCACACGCCC ACCTGCGAGT CACAGCGGCT CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG 
GACCAAAGCG TGCTGCTCAT GAAGCCTGAT GCTGAGCTCT CGGCGTCCTC GGTTTACAAC 
CTGCTACCAG AAAAGGACCT CACTGGCTTC CCTGGGCCTT TGAATGACCA GGACAATGAA 
GACTGCATCA ATCGTCATAA TGTCTATATT AATGGAATCA CATATACTCC AGTATCAAGT 
ACAAATGAAA AGGATATGTA CAGCTTCCTA GAGGACATGG GCTTAAAGGC ATTCACCAAC 
TCAAAGATTC GTAAACCCAA AATGTGTCCA CAGCTTCAAC AGTATGAAAT GCATGGACCT 
GAAGGTCTAC GTGTAGGTTT TTATGAGTCA GATGTAATGG GAAGAGGCCA TGCACGCCTG 
GTGCATGTTG AAGAGCCTCA CACGGAGACC GTACGAAAGT ACTTCCCTGA GACATGGATC 
TGGGATTTGG TGGTGGTAAA CTCAGCAGGT GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC 
ACCATCACCG AGTGGAAGGC AGGGGCCTTC TGCCTGTCTG AAGATGCTGG ACTTGGTATC 
TCTTCCACTG CCTCTCTCCG AGCCTTCCAG CCCTTCTTTG TGGAGCTCAC AATGCCTTAC 
TCTGTGATTC GTGGAGAGGC CTTCACACTC AAGGCCACGG TCCTAAACTA CCTTCCCAAA 
TGCATCCGGG TCAGTGTGCA GCTGGAAGCC TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG 
AAGGAACAAG CGCCTCACTG CATCTGTGCA AACGGGCGGC AAACTGTGTC CTGGGCAGTA 
ACCCCAAAGT CATTAGGAAA TGTGAATTTC ACTGTGAGCG CAGAGGCACT AGAGTCTCAA 
GAGCTGTGTG GGACTGAGGT GCCTTCAGTT CCTGAACACG GAAGGAAAGA CACAGTCATC 
AAGCCTCTGT TGGTTGAACC TGAAGGACTA GAGAAGGAAA CAACATTCAA CTCCCTACTT 
TGTCCATCAG GTGGTGAGGT TTCTGAAGAA TTATCCCTGA AACTGCCACC AAATGTGGTA 
GAAGAATCTG CCCGAGCTTC TGTCTCAGTT TTGGGAGACA TATTAGGCTC TGCCATGCAA 
AACACACAAA ATCTTCTCCA GATGCCCTAT GGCTGTGGAG AGCAGAATAT GGTCCTCTTT 
GCTCCTAACA TCTATGTACT GGATTATCTA AATGAAACAC AGCAGCTTAC TCCAGAGATC 
AAGTCCAAGG CCATTGGCTA TCTCAACACT GGTTACCAGA GACAGTTGAA CTACAAACAC 
TATGATGGCT CCTACAGCAC CTTTGGGGAG CGATATGGCA GGAACCAGGG CAACACCTGG 
CTCACAGCCT TTGTTCTGAA GACTTTTGCC CAAGCTCGAG CCTACATCTT CATCGATGAA 
GCACACATTA CCCAAGCCCT CATATGGCTC TCCCAGAGGC AGAAGGACAA TGGCTGTTTC 
AGGAGCTCTG GGTCACTGCT CAACAATGCC ATAAAGGGAG GAGTAGAAGA TGAAGTGACC 
CTCTCCGCCT ATATCACCAT CGCCCTTCTG GAGATTCCTC TCACAGTCAC TCACCCTGTT 
GTCCGCAATG CCCTGTTTTG CCTGGAGTCA GCCTGGAAGA CAGCACAAGA AGGGGACCAT 
GGCAGCCATG TATATACCAA AGCACTGCTG GCCTATGCTT TTGCCCTGGC AGGTAACCAG 
GACAAGAGGA AGGAAGTACT CAAGTCACTT AATGAGGAAG CTGTGAAGAA AGACAACTCT 
GTCCATTGGG AGCGCCCTCA GAAACCCAAG GCACCAGTGG GGCATTTTTA CGAACCCCAG 
GCTCCCTCTG CTGAGGTGGA GATGACATCC TATGTGCTCC TCGCTTATCT CACGGCCCAG 
CCAGCCCCAA CCTCGGAGGA CCTGACCTCT GCAACCAACA TCGTGAAGTG GATCACGAAG 
CAGCAGAATG CCCAGGGCGG TTTCTCCTCC ACCCAGGACA CAGTGGTGGC TCTCCATGCT 
CTGTCCAAAT ATGGAGCAGC CACATTTACC AGGACTGGGA AGGCTGCACA GGTGACTATC 
CAGTCTTCAG GGACATTTTC CAGCAAATTC CAAGTGGACA ACAACAACCG CCTGTTACTG 
CAGCAGGTCT CATTGCCAGA GCTGCCTGGG GAATACAGCA TGAAAGTGAC AGGAGAAGGA 
TGTGTCTACC TCCAGACATC CTTGAAATAC AATATTCTCC CAGAAAAGGA AGAGTTCCCC 
TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA ACTTGTGATG AACCCAAAGC CCACACCAGC 
TTCCAAATCT CCCTAAGTGT CAGTTACACA GGGAGCCGCT CTGCCTCCAA CATGGCGATC 
GTTGATGTGA AGATGGTCTC TGGCTTCATT CCCCTGAAGC CAACAGTGAA AATGCTTGAA 
AGATCTAACC ATGTGAGCCG GACAGAAGTC AGCAGCAACC ATGTCTTGAT TTACCTTGAT 
AAGGTGTCAA ATCAGACACT GAGCTTGTTC TTCACGGTTC TGCAAGATGT CCCAGTAAGA 
GATCTGAAAC CAGCCATAGT GAAAGTCTAT GATTACTACG AGACGGATGA GTTTGCAATT 
GCTGAGTACA ATGCTCCTTG CAGCAAAGAT CTTGGAAATG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001334352.2
CDS	120..4544
Translation	MGKNKLLHPSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDNEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAPCSKDLGNA

Target ORF information:

RefSeq Version	NM_001347423.2
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001347423.2

ORF Insert Sequence:

ATGGGGAAGA ACAAACTCCT TCATCCAAGT CTGGTTCTTC TCCTCTTGGT CCTCCTGCCC 
ACAGACGCCT CAGTCTCTGG AAAACCGCAG TATATGGTTC TGGTCCCCTC CCTGCTCCAC 
ACTGAGACCA CTGAGAAGGG CTGTGTCCTT CTGAGCTACC TGAATGAGAC AGTGACTGTA 
AGTGCTTCCT TGGAGTCTGT CAGGGGAAAC AGGAGCCTCT TCACTGACCT GGAGGCGGAG 
AATGACGTAC TCCACTGTGT CGCCTTCGCT GTCCCAAAGT CTTCATCCAA TGAGGAGGTA 
ATGTTCCTCA CTGTCCAAGT GAAAGGACCA ACCCAAGAAT TTAAGAAGCG GACCACAGTG 
ATGGTTAAGA ACGAGGACAG TCTGGTCTTT GTCCAGACAG ACAAATCAAT CTACAAACCA 
GGGCAGACAG TGAAATTTCG TGTTGTCTCC ATGGATGAAA ACTTTCACCC CCTGAATGAG 
TTGATTCCAC TAGTATACAT TCAGGATCCC AAAGGAAATC GCATCGCACA ATGGCAGAGT 
TTCCAGTTAG AGGGTGGCCT CAAGCAATTT TCTTTTCCCC TCTCATCAGA GCCCTTCCAG 
GGCTCCTACA AGGTGGTGGT ACAGAAGAAA TCAGGTGGAA GGACAGAGCA CCCTTTCACC 
GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA GTACAAGTAA CAGTGCCAAA GATAATCACC 
ATCTTGGAAG AAGAGATGAA TGTATCAGTG TGTGGCCTAT ACACATATGG GAAGCCTGTC 
CCTGGACATG TGACTGTGAG CATTTGCAGA AAGTATAGTG ACGCTTCCGA CTGCCACGGT 
GAAGATTCAC AGGCTTTCTG TGAGAAATTC AGTGGACAGC TAAACAGCCA TGGCTGCTTC 
TATCAGCAAG TAAAAACCAA GGTCTTCCAG CTGAAGAGGA AGGAGTATGA AATGAAACTT 
CACACTGAGG CCCAGATCCA AGAAGAAGGA ACAGTGGTGG AATTGACTGG AAGGCAGTCC 
AGTGAAATCA CAAGAACCAT AACCAAACTC TCATTTGTGA AAGTGGACTC ACACTTTCGA 
CAGGGAATTC CCTTCTTTGG GCAGGTGCGC CTAGTAGATG GGAAAGGCGT CCCTATACCA 
AATAAAGTCA TATTCATCAG AGGAAATGAA GCAAACTATT ACTCCAATGC TACCACGGAT 
GAGCATGGCC TTGTACAGTT CTCTATCAAC ACCACCAATG TTATGGGTAC CTCTCTTACT 
GTTAGGGTCA ATTACAAGGA TCGTAGTCCC TGTTACGGCT ACCAGTGGGT GTCAGAAGAA 
CACGAAGAGG CACATCACAC TGCTTATCTT GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC 
CTTGAGCCCA TGTCTCATGA ACTACCCTGT GGCCATACTC AGACAGTCCA GGCACATTAT 
ATTCTGAATG GAGGCACCCT GCTGGGGCTG AAGAAGCTCT CCTTCTATTA TCTGATAATG 
GCAAAGGGAG GCATTGTCCG AACTGGGACT CATGGACTGC TTGTGAAGCA GGAAGACATG 
AAGGGCCATT TTTCCATCTC AATCCCTGTG AAGTCAGACA TTGCTCCTGT CGCTCGGTTG 
CTCATCTATG CTGTTTTACC TACCGGGGAC GTGATTGGGG ATTCTGCAAA ATATGATGTT 
GAAAATTGTC TGGCCAACAA GGTGGATTTG AGCTTCAGCC CATCACAAAG TCTCCCAGCC 
TCACACGCCC ACCTGCGAGT CACAGCGGCT CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG 
GACCAAAGCG TGCTGCTCAT GAAGCCTGAT GCTGAGCTCT CGGCGTCCTC GGTTTACAAC 
CTGCTACCAG AAAAGGACCT CACTGGCTTC CCTGGGCCTT TGAATGACCA GGACAATGAA 
GACTGCATCA ATCGTCATAA TGTCTATATT AATGGAATCA CATATACTCC AGTATCAAGT 
ACAAATGAAA AGGATATGTA CAGCTTCCTA GAGGACATGG GCTTAAAGGC ATTCACCAAC 
TCAAAGATTC GTAAACCCAA AATGTGTCCA CAGCTTCAAC AGTATGAAAT GCATGGACCT 
GAAGGTCTAC GTGTAGGTTT TTATGAGTCA GATGTAATGG GAAGAGGCCA TGCACGCCTG 
GTGCATGTTG AAGAGCCTCA CACGGAGACC GTACGAAAGT ACTTCCCTGA GACATGGATC 
TGGGATTTGG TGGTGGTAAA CTCAGCAGGT GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC 
ACCATCACCG AGTGGAAGGC AGGGGCCTTC TGCCTGTCTG AAGATGCTGG ACTTGGTATC 
TCTTCCACTG CCTCTCTCCG AGCCTTCCAG CCCTTCTTTG TGGAGCTCAC AATGCCTTAC 
TCTGTGATTC GTGGAGAGGC CTTCACACTC AAGGCCACGG TCCTAAACTA CCTTCCCAAA 
TGCATCCGGG TCAGTGTGCA GCTGGAAGCC TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG 
AAGGAACAAG CGCCTCACTG CATCTGTGCA AACGGGCGGC AAACTGTGTC CTGGGCAGTA 
ACCCCAAAGT CATTAGGAAA TGTGAATTTC ACTGTGAGCG CAGAGGCACT AGAGTCTCAA 
GAGCTGTGTG GGACTGAGGT GCCTTCAGTT CCTGAACACG GAAGGAAAGA CACAGTCATC 
AAGCCTCTGT TGGTTGAACC TGAAGGACTA GAGAAGGAAA CAACATTCAA CTCCCTACTT 
TGTCCATCAG GTGGTGAGGT TTCTGAAGAA TTATCCCTGA AACTGCCACC AAATGTGGTA 
GAAGAATCTG CCCGAGCTTC TGTCTCAGTT TTGGGAGACA TATTAGGCTC TGCCATGCAA 
AACACACAAA ATCTTCTCCA GATGCCCTAT GGCTGTGGAG AGCAGAATAT GGTCCTCTTT 
GCTCCTAACA TCTATGTACT GGATTATCTA AATGAAACAC AGCAGCTTAC TCCAGAGATC 
AAGTCCAAGG CCATTGGCTA TCTCAACACT GGTTACCAGA GACAGTTGAA CTACAAACAC 
TATGATGGCT CCTACAGCAC CTTTGGGGAG CGATATGGCA GGAACCAGGG CAACACCTGG 
CTCACAGCCT TTGTTCTGAA GACTTTTGCC CAAGCTCGAG CCTACATCTT CATCGATGAA 
GCACACATTA CCCAAGCCCT CATATGGCTC TCCCAGAGGC AGAAGGACAA TGGCTGTTTC 
AGGAGCTCTG GGTCACTGCT CAACAATGCC ATAAAGGGAG GAGTAGAAGA TGAAGTGACC 
CTCTCCGCCT ATATCACCAT CGCCCTTCTG GAGATTCCTC TCACAGTCAC TCACCCTGTT 
GTCCGCAATG CCCTGTTTTG CCTGGAGTCA GCCTGGAAGA CAGCACAAGA AGGGGACCAT 
GGCAGCCATG TATATACCAA AGCACTGCTG GCCTATGCTT TTGCCCTGGC AGGTAACCAG 
GACAAGAGGA AGGAAGTACT CAAGTCACTT AATGAGGAAG CTGTGAAGAA AGACAACTCT 
GTCCATTGGG AGCGCCCTCA GAAACCCAAG GCACCAGTGG GGCATTTTTA CGAACCCCAG 
GCTCCCTCTG CTGAGGTGGA GATGACATCC TATGTGCTCC TCGCTTATCT CACGGCCCAG 
CCAGCCCCAA CCTCGGAGGA CCTGACCTCT GCAACCAACA TCGTGAAGTG GATCACGAAG 
CAGCAGAATG CCCAGGGCGG TTTCTCCTCC ACCCAGGACA CAGTGGTGGC TCTCCATGCT 
CTGTCCAAAT ATGGAGCAGC CACATTTACC AGGACTGGGA AGGCTGCACA GGTGACTATC 
CAGTCTTCAG GGACATTTTC CAGCAAATTC CAAGTGGACA ACAACAACCG CCTGTTACTG 
CAGCAGGTCT CATTGCCAGA GCTGCCTGGG GAATACAGCA TGAAAGTGAC AGGAGAAGGA 
TGTGTCTACC TCCAGACATC CTTGAAATAC AATATTCTCC CAGAAAAGGA AGAGTTCCCC 
TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA ACTTGTGATG AACCCAAAGC CCACACCAGC 
TTCCAAATCT CCCTAAGTGT CAGTTACACA GGGAGCCGCT CTGCCTCCAA CATGGCGATC 
GTTGATGTGA AGATGGTCTC TGGCTTCATT CCCCTGAAGC CAACAGTGAA AATGCTTGAA 
AGATCTAACC ATGTGAGCCG GACAGAAGTC AGCAGCAACC ATGTCTTGAT TTACCTTGAT 
AAGGTGTCAA ATCAGACACT GAGCTTGTTC TTCACGGTTC TGCAAGATGT CCCAGTAAGA 
GATCTGAAAC CAGCCATAGT GAAAGTCTAT GATTACTACG AGACGGATGA GTTTGCAATT 
GCTGAGTACA ATGCTCCTTG CAGCAAAGAT CTTGGAAATG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

A2M ( NM_000014.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_000005.3 Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 1, mRNA.

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CloneID	OHu108400
Clone ID Related Accession (Same CDS sequence)	NM_001347423.2 , NM_000014.6
Accession Version	NM_000014.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4425bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-29
Organism	Homo sapiens(human)
Product	alpha-2-macroglobulin isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC007436.1. On Nov 30, 2019 this sequence version replaced NM_000014.5. Transcript Variant: This variant (1) encodes the longest isoform (a). Both variants 1 and 2 encode isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC040071.1, AB209614.2 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGAAGA ACAAACTCCT TCATCCAAGT CTGGTTCTTC TCCTCTTGGT CCTCCTGCCC 
ACAGACGCCT CAGTCTCTGG AAAACCGCAG TATATGGTTC TGGTCCCCTC CCTGCTCCAC 
ACTGAGACCA CTGAGAAGGG CTGTGTCCTT CTGAGCTACC TGAATGAGAC AGTGACTGTA 
AGTGCTTCCT TGGAGTCTGT CAGGGGAAAC AGGAGCCTCT TCACTGACCT GGAGGCGGAG 
AATGACGTAC TCCACTGTGT CGCCTTCGCT GTCCCAAAGT CTTCATCCAA TGAGGAGGTA 
ATGTTCCTCA CTGTCCAAGT GAAAGGACCA ACCCAAGAAT TTAAGAAGCG GACCACAGTG 
ATGGTTAAGA ACGAGGACAG TCTGGTCTTT GTCCAGACAG ACAAATCAAT CTACAAACCA 
GGGCAGACAG TGAAATTTCG TGTTGTCTCC ATGGATGAAA ACTTTCACCC CCTGAATGAG 
TTGATTCCAC TAGTATACAT TCAGGATCCC AAAGGAAATC GCATCGCACA ATGGCAGAGT 
TTCCAGTTAG AGGGTGGCCT CAAGCAATTT TCTTTTCCCC TCTCATCAGA GCCCTTCCAG 
GGCTCCTACA AGGTGGTGGT ACAGAAGAAA TCAGGTGGAA GGACAGAGCA CCCTTTCACC 
GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA GTACAAGTAA CAGTGCCAAA GATAATCACC 
ATCTTGGAAG AAGAGATGAA TGTATCAGTG TGTGGCCTAT ACACATATGG GAAGCCTGTC 
CCTGGACATG TGACTGTGAG CATTTGCAGA AAGTATAGTG ACGCTTCCGA CTGCCACGGT 
GAAGATTCAC AGGCTTTCTG TGAGAAATTC AGTGGACAGC TAAACAGCCA TGGCTGCTTC 
TATCAGCAAG TAAAAACCAA GGTCTTCCAG CTGAAGAGGA AGGAGTATGA AATGAAACTT 
CACACTGAGG CCCAGATCCA AGAAGAAGGA ACAGTGGTGG AATTGACTGG AAGGCAGTCC 
AGTGAAATCA CAAGAACCAT AACCAAACTC TCATTTGTGA AAGTGGACTC ACACTTTCGA 
CAGGGAATTC CCTTCTTTGG GCAGGTGCGC CTAGTAGATG GGAAAGGCGT CCCTATACCA 
AATAAAGTCA TATTCATCAG AGGAAATGAA GCAAACTATT ACTCCAATGC TACCACGGAT 
GAGCATGGCC TTGTACAGTT CTCTATCAAC ACCACCAATG TTATGGGTAC CTCTCTTACT 
GTTAGGGTCA ATTACAAGGA TCGTAGTCCC TGTTACGGCT ACCAGTGGGT GTCAGAAGAA 
CACGAAGAGG CACATCACAC TGCTTATCTT GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC 
CTTGAGCCCA TGTCTCATGA ACTACCCTGT GGCCATACTC AGACAGTCCA GGCACATTAT 
ATTCTGAATG GAGGCACCCT GCTGGGGCTG AAGAAGCTCT CCTTCTATTA TCTGATAATG 
GCAAAGGGAG GCATTGTCCG AACTGGGACT CATGGACTGC TTGTGAAGCA GGAAGACATG 
AAGGGCCATT TTTCCATCTC AATCCCTGTG AAGTCAGACA TTGCTCCTGT CGCTCGGTTG 
CTCATCTATG CTGTTTTACC TACCGGGGAC GTGATTGGGG ATTCTGCAAA ATATGATGTT 
GAAAATTGTC TGGCCAACAA GGTGGATTTG AGCTTCAGCC CATCACAAAG TCTCCCAGCC 
TCACACGCCC ACCTGCGAGT CACAGCGGCT CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG 
GACCAAAGCG TGCTGCTCAT GAAGCCTGAT GCTGAGCTCT CGGCGTCCTC GGTTTACAAC 
CTGCTACCAG AAAAGGACCT CACTGGCTTC CCTGGGCCTT TGAATGACCA GGACAATGAA 
GACTGCATCA ATCGTCATAA TGTCTATATT AATGGAATCA CATATACTCC AGTATCAAGT 
ACAAATGAAA AGGATATGTA CAGCTTCCTA GAGGACATGG GCTTAAAGGC ATTCACCAAC 
TCAAAGATTC GTAAACCCAA AATGTGTCCA CAGCTTCAAC AGTATGAAAT GCATGGACCT 
GAAGGTCTAC GTGTAGGTTT TTATGAGTCA GATGTAATGG GAAGAGGCCA TGCACGCCTG 
GTGCATGTTG AAGAGCCTCA CACGGAGACC GTACGAAAGT ACTTCCCTGA GACATGGATC 
TGGGATTTGG TGGTGGTAAA CTCAGCAGGT GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC 
ACCATCACCG AGTGGAAGGC AGGGGCCTTC TGCCTGTCTG AAGATGCTGG ACTTGGTATC 
TCTTCCACTG CCTCTCTCCG AGCCTTCCAG CCCTTCTTTG TGGAGCTCAC AATGCCTTAC 
TCTGTGATTC GTGGAGAGGC CTTCACACTC AAGGCCACGG TCCTAAACTA CCTTCCCAAA 
TGCATCCGGG TCAGTGTGCA GCTGGAAGCC TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG 
AAGGAACAAG CGCCTCACTG CATCTGTGCA AACGGGCGGC AAACTGTGTC CTGGGCAGTA 
ACCCCAAAGT CATTAGGAAA TGTGAATTTC ACTGTGAGCG CAGAGGCACT AGAGTCTCAA 
GAGCTGTGTG GGACTGAGGT GCCTTCAGTT CCTGAACACG GAAGGAAAGA CACAGTCATC 
AAGCCTCTGT TGGTTGAACC TGAAGGACTA GAGAAGGAAA CAACATTCAA CTCCCTACTT 
TGTCCATCAG GTGGTGAGGT TTCTGAAGAA TTATCCCTGA AACTGCCACC AAATGTGGTA 
GAAGAATCTG CCCGAGCTTC TGTCTCAGTT TTGGGAGACA TATTAGGCTC TGCCATGCAA 
AACACACAAA ATCTTCTCCA GATGCCCTAT GGCTGTGGAG AGCAGAATAT GGTCCTCTTT 
GCTCCTAACA TCTATGTACT GGATTATCTA AATGAAACAC AGCAGCTTAC TCCAGAGATC 
AAGTCCAAGG CCATTGGCTA TCTCAACACT GGTTACCAGA GACAGTTGAA CTACAAACAC 
TATGATGGCT CCTACAGCAC CTTTGGGGAG CGATATGGCA GGAACCAGGG CAACACCTGG 
CTCACAGCCT TTGTTCTGAA GACTTTTGCC CAAGCTCGAG CCTACATCTT CATCGATGAA 
GCACACATTA CCCAAGCCCT CATATGGCTC TCCCAGAGGC AGAAGGACAA TGGCTGTTTC 
AGGAGCTCTG GGTCACTGCT CAACAATGCC ATAAAGGGAG GAGTAGAAGA TGAAGTGACC 
CTCTCCGCCT ATATCACCAT CGCCCTTCTG GAGATTCCTC TCACAGTCAC TCACCCTGTT 
GTCCGCAATG CCCTGTTTTG CCTGGAGTCA GCCTGGAAGA CAGCACAAGA AGGGGACCAT 
GGCAGCCATG TATATACCAA AGCACTGCTG GCCTATGCTT TTGCCCTGGC AGGTAACCAG 
GACAAGAGGA AGGAAGTACT CAAGTCACTT AATGAGGAAG CTGTGAAGAA AGACAACTCT 
GTCCATTGGG AGCGCCCTCA GAAACCCAAG GCACCAGTGG GGCATTTTTA CGAACCCCAG 
GCTCCCTCTG CTGAGGTGGA GATGACATCC TATGTGCTCC TCGCTTATCT CACGGCCCAG 
CCAGCCCCAA CCTCGGAGGA CCTGACCTCT GCAACCAACA TCGTGAAGTG GATCACGAAG 
CAGCAGAATG CCCAGGGCGG TTTCTCCTCC ACCCAGGACA CAGTGGTGGC TCTCCATGCT 
CTGTCCAAAT ATGGAGCAGC CACATTTACC AGGACTGGGA AGGCTGCACA GGTGACTATC 
CAGTCTTCAG GGACATTTTC CAGCAAATTC CAAGTGGACA ACAACAACCG CCTGTTACTG 
CAGCAGGTCT CATTGCCAGA GCTGCCTGGG GAATACAGCA TGAAAGTGAC AGGAGAAGGA 
TGTGTCTACC TCCAGACATC CTTGAAATAC AATATTCTCC CAGAAAAGGA AGAGTTCCCC 
TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA ACTTGTGATG AACCCAAAGC CCACACCAGC 
TTCCAAATCT CCCTAAGTGT CAGTTACACA GGGAGCCGCT CTGCCTCCAA CATGGCGATC 
GTTGATGTGA AGATGGTCTC TGGCTTCATT CCCCTGAAGC CAACAGTGAA AATGCTTGAA 
AGATCTAACC ATGTGAGCCG GACAGAAGTC AGCAGCAACC ATGTCTTGAT TTACCTTGAT 
AAGGTGTCAA ATCAGACACT GAGCTTGTTC TTCACGGTTC TGCAAGATGT CCCAGTAAGA 
GATCTGAAAC CAGCCATAGT GAAAGTCTAT GATTACTACG AGACGGATGA GTTTGCAATT 
GCTGAGTACA ATGCTCCTTG CAGCAAAGAT CTTGGAAATG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000005.3
CDS	71..4495
Translation	MGKNKLLHPSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDNEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAPCSKDLGNA

Target ORF information:

RefSeq Version	NM_000014.6
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000014.6

ORF Insert Sequence:

ATGGGGAAGA ACAAACTCCT TCATCCAAGT CTGGTTCTTC TCCTCTTGGT CCTCCTGCCC 
ACAGACGCCT CAGTCTCTGG AAAACCGCAG TATATGGTTC TGGTCCCCTC CCTGCTCCAC 
ACTGAGACCA CTGAGAAGGG CTGTGTCCTT CTGAGCTACC TGAATGAGAC AGTGACTGTA 
AGTGCTTCCT TGGAGTCTGT CAGGGGAAAC AGGAGCCTCT TCACTGACCT GGAGGCGGAG 
AATGACGTAC TCCACTGTGT CGCCTTCGCT GTCCCAAAGT CTTCATCCAA TGAGGAGGTA 
ATGTTCCTCA CTGTCCAAGT GAAAGGACCA ACCCAAGAAT TTAAGAAGCG GACCACAGTG 
ATGGTTAAGA ACGAGGACAG TCTGGTCTTT GTCCAGACAG ACAAATCAAT CTACAAACCA 
GGGCAGACAG TGAAATTTCG TGTTGTCTCC ATGGATGAAA ACTTTCACCC CCTGAATGAG 
TTGATTCCAC TAGTATACAT TCAGGATCCC AAAGGAAATC GCATCGCACA ATGGCAGAGT 
TTCCAGTTAG AGGGTGGCCT CAAGCAATTT TCTTTTCCCC TCTCATCAGA GCCCTTCCAG 
GGCTCCTACA AGGTGGTGGT ACAGAAGAAA TCAGGTGGAA GGACAGAGCA CCCTTTCACC 
GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA GTACAAGTAA CAGTGCCAAA GATAATCACC 
ATCTTGGAAG AAGAGATGAA TGTATCAGTG TGTGGCCTAT ACACATATGG GAAGCCTGTC 
CCTGGACATG TGACTGTGAG CATTTGCAGA AAGTATAGTG ACGCTTCCGA CTGCCACGGT 
GAAGATTCAC AGGCTTTCTG TGAGAAATTC AGTGGACAGC TAAACAGCCA TGGCTGCTTC 
TATCAGCAAG TAAAAACCAA GGTCTTCCAG CTGAAGAGGA AGGAGTATGA AATGAAACTT 
CACACTGAGG CCCAGATCCA AGAAGAAGGA ACAGTGGTGG AATTGACTGG AAGGCAGTCC 
AGTGAAATCA CAAGAACCAT AACCAAACTC TCATTTGTGA AAGTGGACTC ACACTTTCGA 
CAGGGAATTC CCTTCTTTGG GCAGGTGCGC CTAGTAGATG GGAAAGGCGT CCCTATACCA 
AATAAAGTCA TATTCATCAG AGGAAATGAA GCAAACTATT ACTCCAATGC TACCACGGAT 
GAGCATGGCC TTGTACAGTT CTCTATCAAC ACCACCAATG TTATGGGTAC CTCTCTTACT 
GTTAGGGTCA ATTACAAGGA TCGTAGTCCC TGTTACGGCT ACCAGTGGGT GTCAGAAGAA 
CACGAAGAGG CACATCACAC TGCTTATCTT GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC 
CTTGAGCCCA TGTCTCATGA ACTACCCTGT GGCCATACTC AGACAGTCCA GGCACATTAT 
ATTCTGAATG GAGGCACCCT GCTGGGGCTG AAGAAGCTCT CCTTCTATTA TCTGATAATG 
GCAAAGGGAG GCATTGTCCG AACTGGGACT CATGGACTGC TTGTGAAGCA GGAAGACATG 
AAGGGCCATT TTTCCATCTC AATCCCTGTG AAGTCAGACA TTGCTCCTGT CGCTCGGTTG 
CTCATCTATG CTGTTTTACC TACCGGGGAC GTGATTGGGG ATTCTGCAAA ATATGATGTT 
GAAAATTGTC TGGCCAACAA GGTGGATTTG AGCTTCAGCC CATCACAAAG TCTCCCAGCC 
TCACACGCCC ACCTGCGAGT CACAGCGGCT CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG 
GACCAAAGCG TGCTGCTCAT GAAGCCTGAT GCTGAGCTCT CGGCGTCCTC GGTTTACAAC 
CTGCTACCAG AAAAGGACCT CACTGGCTTC CCTGGGCCTT TGAATGACCA GGACAATGAA 
GACTGCATCA ATCGTCATAA TGTCTATATT AATGGAATCA CATATACTCC AGTATCAAGT 
ACAAATGAAA AGGATATGTA CAGCTTCCTA GAGGACATGG GCTTAAAGGC ATTCACCAAC 
TCAAAGATTC GTAAACCCAA AATGTGTCCA CAGCTTCAAC AGTATGAAAT GCATGGACCT 
GAAGGTCTAC GTGTAGGTTT TTATGAGTCA GATGTAATGG GAAGAGGCCA TGCACGCCTG 
GTGCATGTTG AAGAGCCTCA CACGGAGACC GTACGAAAGT ACTTCCCTGA GACATGGATC 
TGGGATTTGG TGGTGGTAAA CTCAGCAGGT GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC 
ACCATCACCG AGTGGAAGGC AGGGGCCTTC TGCCTGTCTG AAGATGCTGG ACTTGGTATC 
TCTTCCACTG CCTCTCTCCG AGCCTTCCAG CCCTTCTTTG TGGAGCTCAC AATGCCTTAC 
TCTGTGATTC GTGGAGAGGC CTTCACACTC AAGGCCACGG TCCTAAACTA CCTTCCCAAA 
TGCATCCGGG TCAGTGTGCA GCTGGAAGCC TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG 
AAGGAACAAG CGCCTCACTG CATCTGTGCA AACGGGCGGC AAACTGTGTC CTGGGCAGTA 
ACCCCAAAGT CATTAGGAAA TGTGAATTTC ACTGTGAGCG CAGAGGCACT AGAGTCTCAA 
GAGCTGTGTG GGACTGAGGT GCCTTCAGTT CCTGAACACG GAAGGAAAGA CACAGTCATC 
AAGCCTCTGT TGGTTGAACC TGAAGGACTA GAGAAGGAAA CAACATTCAA CTCCCTACTT 
TGTCCATCAG GTGGTGAGGT TTCTGAAGAA TTATCCCTGA AACTGCCACC AAATGTGGTA 
GAAGAATCTG CCCGAGCTTC TGTCTCAGTT TTGGGAGACA TATTAGGCTC TGCCATGCAA 
AACACACAAA ATCTTCTCCA GATGCCCTAT GGCTGTGGAG AGCAGAATAT GGTCCTCTTT 
GCTCCTAACA TCTATGTACT GGATTATCTA AATGAAACAC AGCAGCTTAC TCCAGAGATC 
AAGTCCAAGG CCATTGGCTA TCTCAACACT GGTTACCAGA GACAGTTGAA CTACAAACAC 
TATGATGGCT CCTACAGCAC CTTTGGGGAG CGATATGGCA GGAACCAGGG CAACACCTGG 
CTCACAGCCT TTGTTCTGAA GACTTTTGCC CAAGCTCGAG CCTACATCTT CATCGATGAA 
GCACACATTA CCCAAGCCCT CATATGGCTC TCCCAGAGGC AGAAGGACAA TGGCTGTTTC 
AGGAGCTCTG GGTCACTGCT CAACAATGCC ATAAAGGGAG GAGTAGAAGA TGAAGTGACC 
CTCTCCGCCT ATATCACCAT CGCCCTTCTG GAGATTCCTC TCACAGTCAC TCACCCTGTT 
GTCCGCAATG CCCTGTTTTG CCTGGAGTCA GCCTGGAAGA CAGCACAAGA AGGGGACCAT 
GGCAGCCATG TATATACCAA AGCACTGCTG GCCTATGCTT TTGCCCTGGC AGGTAACCAG 
GACAAGAGGA AGGAAGTACT CAAGTCACTT AATGAGGAAG CTGTGAAGAA AGACAACTCT 
GTCCATTGGG AGCGCCCTCA GAAACCCAAG GCACCAGTGG GGCATTTTTA CGAACCCCAG 
GCTCCCTCTG CTGAGGTGGA GATGACATCC TATGTGCTCC TCGCTTATCT CACGGCCCAG 
CCAGCCCCAA CCTCGGAGGA CCTGACCTCT GCAACCAACA TCGTGAAGTG GATCACGAAG 
CAGCAGAATG CCCAGGGCGG TTTCTCCTCC ACCCAGGACA CAGTGGTGGC TCTCCATGCT 
CTGTCCAAAT ATGGAGCAGC CACATTTACC AGGACTGGGA AGGCTGCACA GGTGACTATC 
CAGTCTTCAG GGACATTTTC CAGCAAATTC CAAGTGGACA ACAACAACCG CCTGTTACTG 
CAGCAGGTCT CATTGCCAGA GCTGCCTGGG GAATACAGCA TGAAAGTGAC AGGAGAAGGA 
TGTGTCTACC TCCAGACATC CTTGAAATAC AATATTCTCC CAGAAAAGGA AGAGTTCCCC 
TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA ACTTGTGATG AACCCAAAGC CCACACCAGC 
TTCCAAATCT CCCTAAGTGT CAGTTACACA GGGAGCCGCT CTGCCTCCAA CATGGCGATC 
GTTGATGTGA AGATGGTCTC TGGCTTCATT CCCCTGAAGC CAACAGTGAA AATGCTTGAA 
AGATCTAACC ATGTGAGCCG GACAGAAGTC AGCAGCAACC ATGTCTTGAT TTACCTTGAT 
AAGGTGTCAA ATCAGACACT GAGCTTGTTC TTCACGGTTC TGCAAGATGT CCCAGTAAGA 
GATCTGAAAC CAGCCATAGT GAAAGTCTAT GATTACTACG AGACGGATGA GTTTGCAATT 
GCTGAGTACA ATGCTCCTTG CAGCAAAGAT CTTGGAAATG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

A2M ( NM_001347424.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001334353.2 Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu109274
Clone ID Related Accession (Same CDS sequence)	NM_001347424.2
Accession Version	NM_001347424.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4125bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-29
Organism	Homo sapiens(human)
Product	alpha-2-macroglobulin isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC007436.1. On Nov 30, 2019 this sequence version replaced NM_001347424.1. Transcript Variant: This variant (3) contains an alternate splice site in the 5' region, and it thus differs in its 5' UTR and initiates translation from a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.221045.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTCCTCA CTGTCCAAGT GAAAGGACCA ACCCAAGAAT TTAAGAAGCG GACCACAGTG 
ATGGTTAAGA ACGAGGACAG TCTGGTCTTT GTCCAGACAG ACAAATCAAT CTACAAACCA 
GGGCAGACAG TGAAATTTCG TGTTGTCTCC ATGGATGAAA ACTTTCACCC CCTGAATGAG 
TTGATTCCAC TAGTATACAT TCAGGATCCC AAAGGAAATC GCATCGCACA ATGGCAGAGT 
TTCCAGTTAG AGGGTGGCCT CAAGCAATTT TCTTTTCCCC TCTCATCAGA GCCCTTCCAG 
GGCTCCTACA AGGTGGTGGT ACAGAAGAAA TCAGGTGGAA GGACAGAGCA CCCTTTCACC 
GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA GTACAAGTAA CAGTGCCAAA GATAATCACC 
ATCTTGGAAG AAGAGATGAA TGTATCAGTG TGTGGCCTAT ACACATATGG GAAGCCTGTC 
CCTGGACATG TGACTGTGAG CATTTGCAGA AAGTATAGTG ACGCTTCCGA CTGCCACGGT 
GAAGATTCAC AGGCTTTCTG TGAGAAATTC AGTGGACAGC TAAACAGCCA TGGCTGCTTC 
TATCAGCAAG TAAAAACCAA GGTCTTCCAG CTGAAGAGGA AGGAGTATGA AATGAAACTT 
CACACTGAGG CCCAGATCCA AGAAGAAGGA ACAGTGGTGG AATTGACTGG AAGGCAGTCC 
AGTGAAATCA CAAGAACCAT AACCAAACTC TCATTTGTGA AAGTGGACTC ACACTTTCGA 
CAGGGAATTC CCTTCTTTGG GCAGGTGCGC CTAGTAGATG GGAAAGGCGT CCCTATACCA 
AATAAAGTCA TATTCATCAG AGGAAATGAA GCAAACTATT ACTCCAATGC TACCACGGAT 
GAGCATGGCC TTGTACAGTT CTCTATCAAC ACCACCAATG TTATGGGTAC CTCTCTTACT 
GTTAGGGTCA ATTACAAGGA TCGTAGTCCC TGTTACGGCT ACCAGTGGGT GTCAGAAGAA 
CACGAAGAGG CACATCACAC TGCTTATCTT GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC 
CTTGAGCCCA TGTCTCATGA ACTACCCTGT GGCCATACTC AGACAGTCCA GGCACATTAT 
ATTCTGAATG GAGGCACCCT GCTGGGGCTG AAGAAGCTCT CCTTCTATTA TCTGATAATG 
GCAAAGGGAG GCATTGTCCG AACTGGGACT CATGGACTGC TTGTGAAGCA GGAAGACATG 
AAGGGCCATT TTTCCATCTC AATCCCTGTG AAGTCAGACA TTGCTCCTGT CGCTCGGTTG 
CTCATCTATG CTGTTTTACC TACCGGGGAC GTGATTGGGG ATTCTGCAAA ATATGATGTT 
GAAAATTGTC TGGCCAACAA GGTGGATTTG AGCTTCAGCC CATCACAAAG TCTCCCAGCC 
TCACACGCCC ACCTGCGAGT CACAGCGGCT CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG 
GACCAAAGCG TGCTGCTCAT GAAGCCTGAT GCTGAGCTCT CGGCGTCCTC GGTTTACAAC 
CTGCTACCAG AAAAGGACCT CACTGGCTTC CCTGGGCCTT TGAATGACCA GGACAATGAA 
GACTGCATCA ATCGTCATAA TGTCTATATT AATGGAATCA CATATACTCC AGTATCAAGT 
ACAAATGAAA AGGATATGTA CAGCTTCCTA GAGGACATGG GCTTAAAGGC ATTCACCAAC 
TCAAAGATTC GTAAACCCAA AATGTGTCCA CAGCTTCAAC AGTATGAAAT GCATGGACCT 
GAAGGTCTAC GTGTAGGTTT TTATGAGTCA GATGTAATGG GAAGAGGCCA TGCACGCCTG 
GTGCATGTTG AAGAGCCTCA CACGGAGACC GTACGAAAGT ACTTCCCTGA GACATGGATC 
TGGGATTTGG TGGTGGTAAA CTCAGCAGGT GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC 
ACCATCACCG AGTGGAAGGC AGGGGCCTTC TGCCTGTCTG AAGATGCTGG ACTTGGTATC 
TCTTCCACTG CCTCTCTCCG AGCCTTCCAG CCCTTCTTTG TGGAGCTCAC AATGCCTTAC 
TCTGTGATTC GTGGAGAGGC CTTCACACTC AAGGCCACGG TCCTAAACTA CCTTCCCAAA 
TGCATCCGGG TCAGTGTGCA GCTGGAAGCC TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG 
AAGGAACAAG CGCCTCACTG CATCTGTGCA AACGGGCGGC AAACTGTGTC CTGGGCAGTA 
ACCCCAAAGT CATTAGGAAA TGTGAATTTC ACTGTGAGCG CAGAGGCACT AGAGTCTCAA 
GAGCTGTGTG GGACTGAGGT GCCTTCAGTT CCTGAACACG GAAGGAAAGA CACAGTCATC 
AAGCCTCTGT TGGTTGAACC TGAAGGACTA GAGAAGGAAA CAACATTCAA CTCCCTACTT 
TGTCCATCAG GTGGTGAGGT TTCTGAAGAA TTATCCCTGA AACTGCCACC AAATGTGGTA 
GAAGAATCTG CCCGAGCTTC TGTCTCAGTT TTGGGAGACA TATTAGGCTC TGCCATGCAA 
AACACACAAA ATCTTCTCCA GATGCCCTAT GGCTGTGGAG AGCAGAATAT GGTCCTCTTT 
GCTCCTAACA TCTATGTACT GGATTATCTA AATGAAACAC AGCAGCTTAC TCCAGAGATC 
AAGTCCAAGG CCATTGGCTA TCTCAACACT GGTTACCAGA GACAGTTGAA CTACAAACAC 
TATGATGGCT CCTACAGCAC CTTTGGGGAG CGATATGGCA GGAACCAGGG CAACACCTGG 
CTCACAGCCT TTGTTCTGAA GACTTTTGCC CAAGCTCGAG CCTACATCTT CATCGATGAA 
GCACACATTA CCCAAGCCCT CATATGGCTC TCCCAGAGGC AGAAGGACAA TGGCTGTTTC 
AGGAGCTCTG GGTCACTGCT CAACAATGCC ATAAAGGGAG GAGTAGAAGA TGAAGTGACC 
CTCTCCGCCT ATATCACCAT CGCCCTTCTG GAGATTCCTC TCACAGTCAC TCACCCTGTT 
GTCCGCAATG CCCTGTTTTG CCTGGAGTCA GCCTGGAAGA CAGCACAAGA AGGGGACCAT 
GGCAGCCATG TATATACCAA AGCACTGCTG GCCTATGCTT TTGCCCTGGC AGGTAACCAG 
GACAAGAGGA AGGAAGTACT CAAGTCACTT AATGAGGAAG CTGTGAAGAA AGACAACTCT 
GTCCATTGGG AGCGCCCTCA GAAACCCAAG GCACCAGTGG GGCATTTTTA CGAACCCCAG 
GCTCCCTCTG CTGAGGTGGA GATGACATCC TATGTGCTCC TCGCTTATCT CACGGCCCAG 
CCAGCCCCAA CCTCGGAGGA CCTGACCTCT GCAACCAACA TCGTGAAGTG GATCACGAAG 
CAGCAGAATG CCCAGGGCGG TTTCTCCTCC ACCCAGGACA CAGTGGTGGC TCTCCATGCT 
CTGTCCAAAT ATGGAGCAGC CACATTTACC AGGACTGGGA AGGCTGCACA GGTGACTATC 
CAGTCTTCAG GGACATTTTC CAGCAAATTC CAAGTGGACA ACAACAACCG CCTGTTACTG 
CAGCAGGTCT CATTGCCAGA GCTGCCTGGG GAATACAGCA TGAAAGTGAC AGGAGAAGGA 
TGTGTCTACC TCCAGACATC CTTGAAATAC AATATTCTCC CAGAAAAGGA AGAGTTCCCC 
TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA ACTTGTGATG AACCCAAAGC CCACACCAGC 
TTCCAAATCT CCCTAAGTGT CAGTTACACA GGGAGCCGCT CTGCCTCCAA CATGGCGATC 
GTTGATGTGA AGATGGTCTC TGGCTTCATT CCCCTGAAGC CAACAGTGAA AATGCTTGAA 
AGATCTAACC ATGTGAGCCG GACAGAAGTC AGCAGCAACC ATGTCTTGAT TTACCTTGAT 
AAGGTGTCAA ATCAGACACT GAGCTTGTTC TTCACGGTTC TGCAAGATGT CCCAGTAAGA 
GATCTGAAAC CAGCCATAGT GAAAGTCTAT GATTACTACG AGACGGATGA GTTTGCAATT 
GCTGAGTACA ATGCTCCTTG CAGCAAAGAT CTTGGAAATG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001334353.2
CDS	524..4648
Translation	MFLTVQVKGPTQEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDNEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAPCSKDLGNA

Target ORF information:

RefSeq Version	NM_001347424.2
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001347424.2

ORF Insert Sequence:

ATGTTCCTCA CTGTCCAAGT GAAAGGACCA ACCCAAGAAT TTAAGAAGCG GACCACAGTG 
ATGGTTAAGA ACGAGGACAG TCTGGTCTTT GTCCAGACAG ACAAATCAAT CTACAAACCA 
GGGCAGACAG TGAAATTTCG TGTTGTCTCC ATGGATGAAA ACTTTCACCC CCTGAATGAG 
TTGATTCCAC TAGTATACAT TCAGGATCCC AAAGGAAATC GCATCGCACA ATGGCAGAGT 
TTCCAGTTAG AGGGTGGCCT CAAGCAATTT TCTTTTCCCC TCTCATCAGA GCCCTTCCAG 
GGCTCCTACA AGGTGGTGGT ACAGAAGAAA TCAGGTGGAA GGACAGAGCA CCCTTTCACC 
GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA GTACAAGTAA CAGTGCCAAA GATAATCACC 
ATCTTGGAAG AAGAGATGAA TGTATCAGTG TGTGGCCTAT ACACATATGG GAAGCCTGTC 
CCTGGACATG TGACTGTGAG CATTTGCAGA AAGTATAGTG ACGCTTCCGA CTGCCACGGT 
GAAGATTCAC AGGCTTTCTG TGAGAAATTC AGTGGACAGC TAAACAGCCA TGGCTGCTTC 
TATCAGCAAG TAAAAACCAA GGTCTTCCAG CTGAAGAGGA AGGAGTATGA AATGAAACTT 
CACACTGAGG CCCAGATCCA AGAAGAAGGA ACAGTGGTGG AATTGACTGG AAGGCAGTCC 
AGTGAAATCA CAAGAACCAT AACCAAACTC TCATTTGTGA AAGTGGACTC ACACTTTCGA 
CAGGGAATTC CCTTCTTTGG GCAGGTGCGC CTAGTAGATG GGAAAGGCGT CCCTATACCA 
AATAAAGTCA TATTCATCAG AGGAAATGAA GCAAACTATT ACTCCAATGC TACCACGGAT 
GAGCATGGCC TTGTACAGTT CTCTATCAAC ACCACCAATG TTATGGGTAC CTCTCTTACT 
GTTAGGGTCA ATTACAAGGA TCGTAGTCCC TGTTACGGCT ACCAGTGGGT GTCAGAAGAA 
CACGAAGAGG CACATCACAC TGCTTATCTT GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC 
CTTGAGCCCA TGTCTCATGA ACTACCCTGT GGCCATACTC AGACAGTCCA GGCACATTAT 
ATTCTGAATG GAGGCACCCT GCTGGGGCTG AAGAAGCTCT CCTTCTATTA TCTGATAATG 
GCAAAGGGAG GCATTGTCCG AACTGGGACT CATGGACTGC TTGTGAAGCA GGAAGACATG 
AAGGGCCATT TTTCCATCTC AATCCCTGTG AAGTCAGACA TTGCTCCTGT CGCTCGGTTG 
CTCATCTATG CTGTTTTACC TACCGGGGAC GTGATTGGGG ATTCTGCAAA ATATGATGTT 
GAAAATTGTC TGGCCAACAA GGTGGATTTG AGCTTCAGCC CATCACAAAG TCTCCCAGCC 
TCACACGCCC ACCTGCGAGT CACAGCGGCT CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG 
GACCAAAGCG TGCTGCTCAT GAAGCCTGAT GCTGAGCTCT CGGCGTCCTC GGTTTACAAC 
CTGCTACCAG AAAAGGACCT CACTGGCTTC CCTGGGCCTT TGAATGACCA GGACAATGAA 
GACTGCATCA ATCGTCATAA TGTCTATATT AATGGAATCA CATATACTCC AGTATCAAGT 
ACAAATGAAA AGGATATGTA CAGCTTCCTA GAGGACATGG GCTTAAAGGC ATTCACCAAC 
TCAAAGATTC GTAAACCCAA AATGTGTCCA CAGCTTCAAC AGTATGAAAT GCATGGACCT 
GAAGGTCTAC GTGTAGGTTT TTATGAGTCA GATGTAATGG GAAGAGGCCA TGCACGCCTG 
GTGCATGTTG AAGAGCCTCA CACGGAGACC GTACGAAAGT ACTTCCCTGA GACATGGATC 
TGGGATTTGG TGGTGGTAAA CTCAGCAGGT GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC 
ACCATCACCG AGTGGAAGGC AGGGGCCTTC TGCCTGTCTG AAGATGCTGG ACTTGGTATC 
TCTTCCACTG CCTCTCTCCG AGCCTTCCAG CCCTTCTTTG TGGAGCTCAC AATGCCTTAC 
TCTGTGATTC GTGGAGAGGC CTTCACACTC AAGGCCACGG TCCTAAACTA CCTTCCCAAA 
TGCATCCGGG TCAGTGTGCA GCTGGAAGCC TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG 
AAGGAACAAG CGCCTCACTG CATCTGTGCA AACGGGCGGC AAACTGTGTC CTGGGCAGTA 
ACCCCAAAGT CATTAGGAAA TGTGAATTTC ACTGTGAGCG CAGAGGCACT AGAGTCTCAA 
GAGCTGTGTG GGACTGAGGT GCCTTCAGTT CCTGAACACG GAAGGAAAGA CACAGTCATC 
AAGCCTCTGT TGGTTGAACC TGAAGGACTA GAGAAGGAAA CAACATTCAA CTCCCTACTT 
TGTCCATCAG GTGGTGAGGT TTCTGAAGAA TTATCCCTGA AACTGCCACC AAATGTGGTA 
GAAGAATCTG CCCGAGCTTC TGTCTCAGTT TTGGGAGACA TATTAGGCTC TGCCATGCAA 
AACACACAAA ATCTTCTCCA GATGCCCTAT GGCTGTGGAG AGCAGAATAT GGTCCTCTTT 
GCTCCTAACA TCTATGTACT GGATTATCTA AATGAAACAC AGCAGCTTAC TCCAGAGATC 
AAGTCCAAGG CCATTGGCTA TCTCAACACT GGTTACCAGA GACAGTTGAA CTACAAACAC 
TATGATGGCT CCTACAGCAC CTTTGGGGAG CGATATGGCA GGAACCAGGG CAACACCTGG 
CTCACAGCCT TTGTTCTGAA GACTTTTGCC CAAGCTCGAG CCTACATCTT CATCGATGAA 
GCACACATTA CCCAAGCCCT CATATGGCTC TCCCAGAGGC AGAAGGACAA TGGCTGTTTC 
AGGAGCTCTG GGTCACTGCT CAACAATGCC ATAAAGGGAG GAGTAGAAGA TGAAGTGACC 
CTCTCCGCCT ATATCACCAT CGCCCTTCTG GAGATTCCTC TCACAGTCAC TCACCCTGTT 
GTCCGCAATG CCCTGTTTTG CCTGGAGTCA GCCTGGAAGA CAGCACAAGA AGGGGACCAT 
GGCAGCCATG TATATACCAA AGCACTGCTG GCCTATGCTT TTGCCCTGGC AGGTAACCAG 
GACAAGAGGA AGGAAGTACT CAAGTCACTT AATGAGGAAG CTGTGAAGAA AGACAACTCT 
GTCCATTGGG AGCGCCCTCA GAAACCCAAG GCACCAGTGG GGCATTTTTA CGAACCCCAG 
GCTCCCTCTG CTGAGGTGGA GATGACATCC TATGTGCTCC TCGCTTATCT CACGGCCCAG 
CCAGCCCCAA CCTCGGAGGA CCTGACCTCT GCAACCAACA TCGTGAAGTG GATCACGAAG 
CAGCAGAATG CCCAGGGCGG TTTCTCCTCC ACCCAGGACA CAGTGGTGGC TCTCCATGCT 
CTGTCCAAAT ATGGAGCAGC CACATTTACC AGGACTGGGA AGGCTGCACA GGTGACTATC 
CAGTCTTCAG GGACATTTTC CAGCAAATTC CAAGTGGACA ACAACAACCG CCTGTTACTG 
CAGCAGGTCT CATTGCCAGA GCTGCCTGGG GAATACAGCA TGAAAGTGAC AGGAGAAGGA 
TGTGTCTACC TCCAGACATC CTTGAAATAC AATATTCTCC CAGAAAAGGA AGAGTTCCCC 
TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA ACTTGTGATG AACCCAAAGC CCACACCAGC 
TTCCAAATCT CCCTAAGTGT CAGTTACACA GGGAGCCGCT CTGCCTCCAA CATGGCGATC 
GTTGATGTGA AGATGGTCTC TGGCTTCATT CCCCTGAAGC CAACAGTGAA AATGCTTGAA 
AGATCTAACC ATGTGAGCCG GACAGAAGTC AGCAGCAACC ATGTCTTGAT TTACCTTGAT 
AAGGTGTCAA ATCAGACACT GAGCTTGTTC TTCACGGTTC TGCAAGATGT CCCAGTAAGA 
GATCTGAAAC CAGCCATAGT GAAAGTCTAT GATTACTACG AGACGGATGA GTTTGCAATT 
GCTGAGTACA ATGCTCCTTG CAGCAAAGAT CTTGGAAATG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

A2M ( NM_001347425.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001334354.2 Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 4, mRNA.

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CloneID	OHu109275
Clone ID Related Accession (Same CDS sequence)	NM_001347425.2
Accession Version	NM_001347425.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3975bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-29
Organism	Homo sapiens(human)
Product	alpha-2-macroglobulin isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC007436.1. On Nov 30, 2019 this sequence version replaced NM_001347425.1. Transcript Variant: This variant (4) lacks an exon in the 5' region, and it thus differs in its 5' UTR and initiates translation from a downstream in-frame start codon, compared to variant 1. The encoded isoform (c) is shorter at the N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK307832.1, SRR1660807.96034.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATGAAA ACTTTCACCC CCTGAATGAG TTGATTCCAC TAGTATACAT TCAGGATCCC 
AAAGGAAATC GCATCGCACA ATGGCAGAGT TTCCAGTTAG AGGGTGGCCT CAAGCAATTT 
TCTTTTCCCC TCTCATCAGA GCCCTTCCAG GGCTCCTACA AGGTGGTGGT ACAGAAGAAA 
TCAGGTGGAA GGACAGAGCA CCCTTTCACC GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA 
GTACAAGTAA CAGTGCCAAA GATAATCACC ATCTTGGAAG AAGAGATGAA TGTATCAGTG 
TGTGGCCTAT ACACATATGG GAAGCCTGTC CCTGGACATG TGACTGTGAG CATTTGCAGA 
AAGTATAGTG ACGCTTCCGA CTGCCACGGT GAAGATTCAC AGGCTTTCTG TGAGAAATTC 
AGTGGACAGC TAAACAGCCA TGGCTGCTTC TATCAGCAAG TAAAAACCAA GGTCTTCCAG 
CTGAAGAGGA AGGAGTATGA AATGAAACTT CACACTGAGG CCCAGATCCA AGAAGAAGGA 
ACAGTGGTGG AATTGACTGG AAGGCAGTCC AGTGAAATCA CAAGAACCAT AACCAAACTC 
TCATTTGTGA AAGTGGACTC ACACTTTCGA CAGGGAATTC CCTTCTTTGG GCAGGTGCGC 
CTAGTAGATG GGAAAGGCGT CCCTATACCA AATAAAGTCA TATTCATCAG AGGAAATGAA 
GCAAACTATT ACTCCAATGC TACCACGGAT GAGCATGGCC TTGTACAGTT CTCTATCAAC 
ACCACCAATG TTATGGGTAC CTCTCTTACT GTTAGGGTCA ATTACAAGGA TCGTAGTCCC 
TGTTACGGCT ACCAGTGGGT GTCAGAAGAA CACGAAGAGG CACATCACAC TGCTTATCTT 
GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC CTTGAGCCCA TGTCTCATGA ACTACCCTGT 
GGCCATACTC AGACAGTCCA GGCACATTAT ATTCTGAATG GAGGCACCCT GCTGGGGCTG 
AAGAAGCTCT CCTTCTATTA TCTGATAATG GCAAAGGGAG GCATTGTCCG AACTGGGACT 
CATGGACTGC TTGTGAAGCA GGAAGACATG AAGGGCCATT TTTCCATCTC AATCCCTGTG 
AAGTCAGACA TTGCTCCTGT CGCTCGGTTG CTCATCTATG CTGTTTTACC TACCGGGGAC 
GTGATTGGGG ATTCTGCAAA ATATGATGTT GAAAATTGTC TGGCCAACAA GGTGGATTTG 
AGCTTCAGCC CATCACAAAG TCTCCCAGCC TCACACGCCC ACCTGCGAGT CACAGCGGCT 
CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG GACCAAAGCG TGCTGCTCAT GAAGCCTGAT 
GCTGAGCTCT CGGCGTCCTC GGTTTACAAC CTGCTACCAG AAAAGGACCT CACTGGCTTC 
CCTGGGCCTT TGAATGACCA GGACAATGAA GACTGCATCA ATCGTCATAA TGTCTATATT 
AATGGAATCA CATATACTCC AGTATCAAGT ACAAATGAAA AGGATATGTA CAGCTTCCTA 
GAGGACATGG GCTTAAAGGC ATTCACCAAC TCAAAGATTC GTAAACCCAA AATGTGTCCA 
CAGCTTCAAC AGTATGAAAT GCATGGACCT GAAGGTCTAC GTGTAGGTTT TTATGAGTCA 
GATGTAATGG GAAGAGGCCA TGCACGCCTG GTGCATGTTG AAGAGCCTCA CACGGAGACC 
GTACGAAAGT ACTTCCCTGA GACATGGATC TGGGATTTGG TGGTGGTAAA CTCAGCAGGT 
GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC ACCATCACCG AGTGGAAGGC AGGGGCCTTC 
TGCCTGTCTG AAGATGCTGG ACTTGGTATC TCTTCCACTG CCTCTCTCCG AGCCTTCCAG 
CCCTTCTTTG TGGAGCTCAC AATGCCTTAC TCTGTGATTC GTGGAGAGGC CTTCACACTC 
AAGGCCACGG TCCTAAACTA CCTTCCCAAA TGCATCCGGG TCAGTGTGCA GCTGGAAGCC 
TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG AAGGAACAAG CGCCTCACTG CATCTGTGCA 
AACGGGCGGC AAACTGTGTC CTGGGCAGTA ACCCCAAAGT CATTAGGAAA TGTGAATTTC 
ACTGTGAGCG CAGAGGCACT AGAGTCTCAA GAGCTGTGTG GGACTGAGGT GCCTTCAGTT 
CCTGAACACG GAAGGAAAGA CACAGTCATC AAGCCTCTGT TGGTTGAACC TGAAGGACTA 
GAGAAGGAAA CAACATTCAA CTCCCTACTT TGTCCATCAG GTGGTGAGGT TTCTGAAGAA 
TTATCCCTGA AACTGCCACC AAATGTGGTA GAAGAATCTG CCCGAGCTTC TGTCTCAGTT 
TTGGGAGACA TATTAGGCTC TGCCATGCAA AACACACAAA ATCTTCTCCA GATGCCCTAT 
GGCTGTGGAG AGCAGAATAT GGTCCTCTTT GCTCCTAACA TCTATGTACT GGATTATCTA 
AATGAAACAC AGCAGCTTAC TCCAGAGATC AAGTCCAAGG CCATTGGCTA TCTCAACACT 
GGTTACCAGA GACAGTTGAA CTACAAACAC TATGATGGCT CCTACAGCAC CTTTGGGGAG 
CGATATGGCA GGAACCAGGG CAACACCTGG CTCACAGCCT TTGTTCTGAA GACTTTTGCC 
CAAGCTCGAG CCTACATCTT CATCGATGAA GCACACATTA CCCAAGCCCT CATATGGCTC 
TCCCAGAGGC AGAAGGACAA TGGCTGTTTC AGGAGCTCTG GGTCACTGCT CAACAATGCC 
ATAAAGGGAG GAGTAGAAGA TGAAGTGACC CTCTCCGCCT ATATCACCAT CGCCCTTCTG 
GAGATTCCTC TCACAGTCAC TCACCCTGTT GTCCGCAATG CCCTGTTTTG CCTGGAGTCA 
GCCTGGAAGA CAGCACAAGA AGGGGACCAT GGCAGCCATG TATATACCAA AGCACTGCTG 
GCCTATGCTT TTGCCCTGGC AGGTAACCAG GACAAGAGGA AGGAAGTACT CAAGTCACTT 
AATGAGGAAG CTGTGAAGAA AGACAACTCT GTCCATTGGG AGCGCCCTCA GAAACCCAAG 
GCACCAGTGG GGCATTTTTA CGAACCCCAG GCTCCCTCTG CTGAGGTGGA GATGACATCC 
TATGTGCTCC TCGCTTATCT CACGGCCCAG CCAGCCCCAA CCTCGGAGGA CCTGACCTCT 
GCAACCAACA TCGTGAAGTG GATCACGAAG CAGCAGAATG CCCAGGGCGG TTTCTCCTCC 
ACCCAGGACA CAGTGGTGGC TCTCCATGCT CTGTCCAAAT ATGGAGCAGC CACATTTACC 
AGGACTGGGA AGGCTGCACA GGTGACTATC CAGTCTTCAG GGACATTTTC CAGCAAATTC 
CAAGTGGACA ACAACAACCG CCTGTTACTG CAGCAGGTCT CATTGCCAGA GCTGCCTGGG 
GAATACAGCA TGAAAGTGAC AGGAGAAGGA TGTGTCTACC TCCAGACATC CTTGAAATAC 
AATATTCTCC CAGAAAAGGA AGAGTTCCCC TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA 
ACTTGTGATG AACCCAAAGC CCACACCAGC TTCCAAATCT CCCTAAGTGT CAGTTACACA 
GGGAGCCGCT CTGCCTCCAA CATGGCGATC GTTGATGTGA AGATGGTCTC TGGCTTCATT 
CCCCTGAAGC CAACAGTGAA AATGCTTGAA AGATCTAACC ATGTGAGCCG GACAGAAGTC 
AGCAGCAACC ATGTCTTGAT TTACCTTGAT AAGGTGTCAA ATCAGACACT GAGCTTGTTC 
TTCACGGTTC TGCAAGATGT CCCAGTAAGA GATCTGAAAC CAGCCATAGT GAAAGTCTAT 
GATTACTACG AGACGGATGA GTTTGCAATT GCTGAGTACA ATGCTCCTTG CAGCAAAGAT 
CTTGGAAATG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001334354.2
CDS	361..4335
Translation	MDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDNEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAPCSKDLGNA

Target ORF information:

RefSeq Version	NM_001347425.2
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001347425.2

ORF Insert Sequence:

ATGGATGAAA ACTTTCACCC CCTGAATGAG TTGATTCCAC TAGTATACAT TCAGGATCCC 
AAAGGAAATC GCATCGCACA ATGGCAGAGT TTCCAGTTAG AGGGTGGCCT CAAGCAATTT 
TCTTTTCCCC TCTCATCAGA GCCCTTCCAG GGCTCCTACA AGGTGGTGGT ACAGAAGAAA 
TCAGGTGGAA GGACAGAGCA CCCTTTCACC GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA 
GTACAAGTAA CAGTGCCAAA GATAATCACC ATCTTGGAAG AAGAGATGAA TGTATCAGTG 
TGTGGCCTAT ACACATATGG GAAGCCTGTC CCTGGACATG TGACTGTGAG CATTTGCAGA 
AAGTATAGTG ACGCTTCCGA CTGCCACGGT GAAGATTCAC AGGCTTTCTG TGAGAAATTC 
AGTGGACAGC TAAACAGCCA TGGCTGCTTC TATCAGCAAG TAAAAACCAA GGTCTTCCAG 
CTGAAGAGGA AGGAGTATGA AATGAAACTT CACACTGAGG CCCAGATCCA AGAAGAAGGA 
ACAGTGGTGG AATTGACTGG AAGGCAGTCC AGTGAAATCA CAAGAACCAT AACCAAACTC 
TCATTTGTGA AAGTGGACTC ACACTTTCGA CAGGGAATTC CCTTCTTTGG GCAGGTGCGC 
CTAGTAGATG GGAAAGGCGT CCCTATACCA AATAAAGTCA TATTCATCAG AGGAAATGAA 
GCAAACTATT ACTCCAATGC TACCACGGAT GAGCATGGCC TTGTACAGTT CTCTATCAAC 
ACCACCAATG TTATGGGTAC CTCTCTTACT GTTAGGGTCA ATTACAAGGA TCGTAGTCCC 
TGTTACGGCT ACCAGTGGGT GTCAGAAGAA CACGAAGAGG CACATCACAC TGCTTATCTT 
GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC CTTGAGCCCA TGTCTCATGA ACTACCCTGT 
GGCCATACTC AGACAGTCCA GGCACATTAT ATTCTGAATG GAGGCACCCT GCTGGGGCTG 
AAGAAGCTCT CCTTCTATTA TCTGATAATG GCAAAGGGAG GCATTGTCCG AACTGGGACT 
CATGGACTGC TTGTGAAGCA GGAAGACATG AAGGGCCATT TTTCCATCTC AATCCCTGTG 
AAGTCAGACA TTGCTCCTGT CGCTCGGTTG CTCATCTATG CTGTTTTACC TACCGGGGAC 
GTGATTGGGG ATTCTGCAAA ATATGATGTT GAAAATTGTC TGGCCAACAA GGTGGATTTG 
AGCTTCAGCC CATCACAAAG TCTCCCAGCC TCACACGCCC ACCTGCGAGT CACAGCGGCT 
CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG GACCAAAGCG TGCTGCTCAT GAAGCCTGAT 
GCTGAGCTCT CGGCGTCCTC GGTTTACAAC CTGCTACCAG AAAAGGACCT CACTGGCTTC 
CCTGGGCCTT TGAATGACCA GGACAATGAA GACTGCATCA ATCGTCATAA TGTCTATATT 
AATGGAATCA CATATACTCC AGTATCAAGT ACAAATGAAA AGGATATGTA CAGCTTCCTA 
GAGGACATGG GCTTAAAGGC ATTCACCAAC TCAAAGATTC GTAAACCCAA AATGTGTCCA 
CAGCTTCAAC AGTATGAAAT GCATGGACCT GAAGGTCTAC GTGTAGGTTT TTATGAGTCA 
GATGTAATGG GAAGAGGCCA TGCACGCCTG GTGCATGTTG AAGAGCCTCA CACGGAGACC 
GTACGAAAGT ACTTCCCTGA GACATGGATC TGGGATTTGG TGGTGGTAAA CTCAGCAGGT 
GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC ACCATCACCG AGTGGAAGGC AGGGGCCTTC 
TGCCTGTCTG AAGATGCTGG ACTTGGTATC TCTTCCACTG CCTCTCTCCG AGCCTTCCAG 
CCCTTCTTTG TGGAGCTCAC AATGCCTTAC TCTGTGATTC GTGGAGAGGC CTTCACACTC 
AAGGCCACGG TCCTAAACTA CCTTCCCAAA TGCATCCGGG TCAGTGTGCA GCTGGAAGCC 
TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG AAGGAACAAG CGCCTCACTG CATCTGTGCA 
AACGGGCGGC AAACTGTGTC CTGGGCAGTA ACCCCAAAGT CATTAGGAAA TGTGAATTTC 
ACTGTGAGCG CAGAGGCACT AGAGTCTCAA GAGCTGTGTG GGACTGAGGT GCCTTCAGTT 
CCTGAACACG GAAGGAAAGA CACAGTCATC AAGCCTCTGT TGGTTGAACC TGAAGGACTA 
GAGAAGGAAA CAACATTCAA CTCCCTACTT TGTCCATCAG GTGGTGAGGT TTCTGAAGAA 
TTATCCCTGA AACTGCCACC AAATGTGGTA GAAGAATCTG CCCGAGCTTC TGTCTCAGTT 
TTGGGAGACA TATTAGGCTC TGCCATGCAA AACACACAAA ATCTTCTCCA GATGCCCTAT 
GGCTGTGGAG AGCAGAATAT GGTCCTCTTT GCTCCTAACA TCTATGTACT GGATTATCTA 
AATGAAACAC AGCAGCTTAC TCCAGAGATC AAGTCCAAGG CCATTGGCTA TCTCAACACT 
GGTTACCAGA GACAGTTGAA CTACAAACAC TATGATGGCT CCTACAGCAC CTTTGGGGAG 
CGATATGGCA GGAACCAGGG CAACACCTGG CTCACAGCCT TTGTTCTGAA GACTTTTGCC 
CAAGCTCGAG CCTACATCTT CATCGATGAA GCACACATTA CCCAAGCCCT CATATGGCTC 
TCCCAGAGGC AGAAGGACAA TGGCTGTTTC AGGAGCTCTG GGTCACTGCT CAACAATGCC 
ATAAAGGGAG GAGTAGAAGA TGAAGTGACC CTCTCCGCCT ATATCACCAT CGCCCTTCTG 
GAGATTCCTC TCACAGTCAC TCACCCTGTT GTCCGCAATG CCCTGTTTTG CCTGGAGTCA 
GCCTGGAAGA CAGCACAAGA AGGGGACCAT GGCAGCCATG TATATACCAA AGCACTGCTG 
GCCTATGCTT TTGCCCTGGC AGGTAACCAG GACAAGAGGA AGGAAGTACT CAAGTCACTT 
AATGAGGAAG CTGTGAAGAA AGACAACTCT GTCCATTGGG AGCGCCCTCA GAAACCCAAG 
GCACCAGTGG GGCATTTTTA CGAACCCCAG GCTCCCTCTG CTGAGGTGGA GATGACATCC 
TATGTGCTCC TCGCTTATCT CACGGCCCAG CCAGCCCCAA CCTCGGAGGA CCTGACCTCT 
GCAACCAACA TCGTGAAGTG GATCACGAAG CAGCAGAATG CCCAGGGCGG TTTCTCCTCC 
ACCCAGGACA CAGTGGTGGC TCTCCATGCT CTGTCCAAAT ATGGAGCAGC CACATTTACC 
AGGACTGGGA AGGCTGCACA GGTGACTATC CAGTCTTCAG GGACATTTTC CAGCAAATTC 
CAAGTGGACA ACAACAACCG CCTGTTACTG CAGCAGGTCT CATTGCCAGA GCTGCCTGGG 
GAATACAGCA TGAAAGTGAC AGGAGAAGGA TGTGTCTACC TCCAGACATC CTTGAAATAC 
AATATTCTCC CAGAAAAGGA AGAGTTCCCC TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA 
ACTTGTGATG AACCCAAAGC CCACACCAGC TTCCAAATCT CCCTAAGTGT CAGTTACACA 
GGGAGCCGCT CTGCCTCCAA CATGGCGATC GTTGATGTGA AGATGGTCTC TGGCTTCATT 
CCCCTGAAGC CAACAGTGAA AATGCTTGAA AGATCTAACC ATGTGAGCCG GACAGAAGTC 
AGCAGCAACC ATGTCTTGAT TTACCTTGAT AAGGTGTCAA ATCAGACACT GAGCTTGTTC 
TTCACGGTTC TGCAAGATGT CCCAGTAAGA GATCTGAAAC CAGCCATAGT GAAAGTCTAT 
GATTACTACG AGACGGATGA GTTTGCAATT GCTGAGTACA ATGCTCCTTG CAGCAAAGAT 
CTTGGAAATG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

A2M ( NM_001347423.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001334352.1 Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 2, mRNA.

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CloneID	OHu18488
Clone ID Related Accession (Same CDS sequence)	NM_001347423.1 , NM_000014.5
Accession Version	NM_001347423.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4425bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	alpha-2-macroglobulin isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC334781.1, BC040071.1 and AB209614.2. Transcript Variant: This variant (2) splices out a region of the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.140912.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGAAGA ACAAACTCCT TCATCCAAGT CTGGTTCTTC TCCTCTTGGT CCTCCTGCCC 
ACAGACGCCT CAGTCTCTGG AAAACCGCAG TATATGGTTC TGGTCCCCTC CCTGCTCCAC 
ACTGAGACCA CTGAGAAGGG CTGTGTCCTT CTGAGCTACC TGAATGAGAC AGTGACTGTA 
AGTGCTTCCT TGGAGTCTGT CAGGGGAAAC AGGAGCCTCT TCACTGACCT GGAGGCGGAG 
AATGACGTAC TCCACTGTGT CGCCTTCGCT GTCCCAAAGT CTTCATCCAA TGAGGAGGTA 
ATGTTCCTCA CTGTCCAAGT GAAAGGACCA ACCCAAGAAT TTAAGAAGCG GACCACAGTG 
ATGGTTAAGA ACGAGGACAG TCTGGTCTTT GTCCAGACAG ACAAATCAAT CTACAAACCA 
GGGCAGACAG TGAAATTTCG TGTTGTCTCC ATGGATGAAA ACTTTCACCC CCTGAATGAG 
TTGATTCCAC TAGTATACAT TCAGGATCCC AAAGGAAATC GCATCGCACA ATGGCAGAGT 
TTCCAGTTAG AGGGTGGCCT CAAGCAATTT TCTTTTCCCC TCTCATCAGA GCCCTTCCAG 
GGCTCCTACA AGGTGGTGGT ACAGAAGAAA TCAGGTGGAA GGACAGAGCA CCCTTTCACC 
GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA GTACAAGTAA CAGTGCCAAA GATAATCACC 
ATCTTGGAAG AAGAGATGAA TGTATCAGTG TGTGGCCTAT ACACATATGG GAAGCCTGTC 
CCTGGACATG TGACTGTGAG CATTTGCAGA AAGTATAGTG ACGCTTCCGA CTGCCACGGT 
GAAGATTCAC AGGCTTTCTG TGAGAAATTC AGTGGACAGC TAAACAGCCA TGGCTGCTTC 
TATCAGCAAG TAAAAACCAA GGTCTTCCAG CTGAAGAGGA AGGAGTATGA AATGAAACTT 
CACACTGAGG CCCAGATCCA AGAAGAAGGA ACAGTGGTGG AATTGACTGG AAGGCAGTCC 
AGTGAAATCA CAAGAACCAT AACCAAACTC TCATTTGTGA AAGTGGACTC ACACTTTCGA 
CAGGGAATTC CCTTCTTTGG GCAGGTGCGC CTAGTAGATG GGAAAGGCGT CCCTATACCA 
AATAAAGTCA TATTCATCAG AGGAAATGAA GCAAACTATT ACTCCAATGC TACCACGGAT 
GAGCATGGCC TTGTACAGTT CTCTATCAAC ACCACCAATG TTATGGGTAC CTCTCTTACT 
GTTAGGGTCA ATTACAAGGA TCGTAGTCCC TGTTACGGCT ACCAGTGGGT GTCAGAAGAA 
CACGAAGAGG CACATCACAC TGCTTATCTT GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC 
CTTGAGCCCA TGTCTCATGA ACTACCCTGT GGCCATACTC AGACAGTCCA GGCACATTAT 
ATTCTGAATG GAGGCACCCT GCTGGGGCTG AAGAAGCTCT CCTTCTATTA TCTGATAATG 
GCAAAGGGAG GCATTGTCCG AACTGGGACT CATGGACTGC TTGTGAAGCA GGAAGACATG 
AAGGGCCATT TTTCCATCTC AATCCCTGTG AAGTCAGACA TTGCTCCTGT CGCTCGGTTG 
CTCATCTATG CTGTTTTACC TACCGGGGAC GTGATTGGGG ATTCTGCAAA ATATGATGTT 
GAAAATTGTC TGGCCAACAA GGTGGATTTG AGCTTCAGCC CATCACAAAG TCTCCCAGCC 
TCACACGCCC ACCTGCGAGT CACAGCGGCT CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG 
GACCAAAGCG TGCTGCTCAT GAAGCCTGAT GCTGAGCTCT CGGCGTCCTC GGTTTACAAC 
CTGCTACCAG AAAAGGACCT CACTGGCTTC CCTGGGCCTT TGAATGACCA GGACGATGAA 
GACTGCATCA ATCGTCATAA TGTCTATATT AATGGAATCA CATATACTCC AGTATCAAGT 
ACAAATGAAA AGGATATGTA CAGCTTCCTA GAGGACATGG GCTTAAAGGC ATTCACCAAC 
TCAAAGATTC GTAAACCCAA AATGTGTCCA CAGCTTCAAC AGTATGAAAT GCATGGACCT 
GAAGGTCTAC GTGTAGGTTT TTATGAGTCA GATGTAATGG GAAGAGGCCA TGCACGCCTG 
GTGCATGTTG AAGAGCCTCA CACGGAGACC GTACGAAAGT ACTTCCCTGA GACATGGATC 
TGGGATTTGG TGGTGGTAAA CTCAGCAGGT GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC 
ACCATCACCG AGTGGAAGGC AGGGGCCTTC TGCCTGTCTG AAGATGCTGG ACTTGGTATC 
TCTTCCACTG CCTCTCTCCG AGCCTTCCAG CCCTTCTTTG TGGAGCTCAC AATGCCTTAC 
TCTGTGATTC GTGGAGAGGC CTTCACACTC AAGGCCACGG TCCTAAACTA CCTTCCCAAA 
TGCATCCGGG TCAGTGTGCA GCTGGAAGCC TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG 
AAGGAACAAG CGCCTCACTG CATCTGTGCA AACGGGCGGC AAACTGTGTC CTGGGCAGTA 
ACCCCAAAGT CATTAGGAAA TGTGAATTTC ACTGTGAGCG CAGAGGCACT AGAGTCTCAA 
GAGCTGTGTG GGACTGAGGT GCCTTCAGTT CCTGAACACG GAAGGAAAGA CACAGTCATC 
AAGCCTCTGT TGGTTGAACC TGAAGGACTA GAGAAGGAAA CAACATTCAA CTCCCTACTT 
TGTCCATCAG GTGGTGAGGT TTCTGAAGAA TTATCCCTGA AACTGCCACC AAATGTGGTA 
GAAGAATCTG CCCGAGCTTC TGTCTCAGTT TTGGGAGACA TATTAGGCTC TGCCATGCAA 
AACACACAAA ATCTTCTCCA GATGCCCTAT GGCTGTGGAG AGCAGAATAT GGTCCTCTTT 
GCTCCTAACA TCTATGTACT GGATTATCTA AATGAAACAC AGCAGCTTAC TCCAGAGATC 
AAGTCCAAGG CCATTGGCTA TCTCAACACT GGTTACCAGA GACAGTTGAA CTACAAACAC 
TATGATGGCT CCTACAGCAC CTTTGGGGAG CGATATGGCA GGAACCAGGG CAACACCTGG 
CTCACAGCCT TTGTTCTGAA GACTTTTGCC CAAGCTCGAG CCTACATCTT CATCGATGAA 
GCACACATTA CCCAAGCCCT CATATGGCTC TCCCAGAGGC AGAAGGACAA TGGCTGTTTC 
AGGAGCTCTG GGTCACTGCT CAACAATGCC ATAAAGGGAG GAGTAGAAGA TGAAGTGACC 
CTCTCCGCCT ATATCACCAT CGCCCTTCTG GAGATTCCTC TCACAGTCAC TCACCCTGTT 
GTCCGCAATG CCCTGTTTTG CCTGGAGTCA GCCTGGAAGA CAGCACAAGA AGGGGACCAT 
GGCAGCCATG TATATACCAA AGCACTGCTG GCCTATGCTT TTGCCCTGGC AGGTAACCAG 
GACAAGAGGA AGGAAGTACT CAAGTCACTT AATGAGGAAG CTGTGAAGAA AGACAACTCT 
GTCCATTGGG AGCGCCCTCA GAAACCCAAG GCACCAGTGG GGCATTTTTA CGAACCCCAG 
GCTCCCTCTG CTGAGGTGGA GATGACATCC TATGTGCTCC TCGCTTATCT CACGGCCCAG 
CCAGCCCCAA CCTCGGAGGA CCTGACCTCT GCAACCAACA TCGTGAAGTG GATCACGAAG 
CAGCAGAATG CCCAGGGCGG TTTCTCCTCC ACCCAGGACA CAGTGGTGGC TCTCCATGCT 
CTGTCCAAAT ATGGAGCAGC CACATTTACC AGGACTGGGA AGGCTGCACA GGTGACTATC 
CAGTCTTCAG GGACATTTTC CAGCAAATTC CAAGTGGACA ACAACAACCG CCTGTTACTG 
CAGCAGGTCT CATTGCCAGA GCTGCCTGGG GAATACAGCA TGAAAGTGAC AGGAGAAGGA 
TGTGTCTACC TCCAGACATC CTTGAAATAC AATATTCTCC CAGAAAAGGA AGAGTTCCCC 
TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA ACTTGTGATG AACCCAAAGC CCACACCAGC 
TTCCAAATCT CCCTAAGTGT CAGTTACACA GGGAGCCGCT CTGCCTCCAA CATGGCGATC 
GTTGATGTGA AGATGGTCTC TGGCTTCATT CCCCTGAAGC CAACAGTGAA AATGCTTGAA 
AGATCTAACC ATGTGAGCCG GACAGAAGTC AGCAGCAACC ATGTCTTGAT TTACCTTGAT 
AAGGTGTCAA ATCAGACACT GAGCTTGTTC TTCACGGTTC TGCAAGATGT CCCAGTAAGA 
GATCTGAAAC CAGCCATAGT GAAAGTCTAT GATTACTACG AGACGGATGA GTTTGCAATT 
GCTGAGTACA ATGCTCCTTG CAGCAAAGAT CTTGGAAATG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001334352.1
CDS	120..4544
Translation	MGKNKLLHPSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDDEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAPCSKDLGNA

Target ORF information:

RefSeq Version	NM_001347423.1
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001347423.1

ORF Insert Sequence:

ATGGGGAAGA ACAAACTCCT TCATCCAAGT CTGGTTCTTC TCCTCTTGGT CCTCCTGCCC 
ACAGACGCCT CAGTCTCTGG AAAACCGCAG TATATGGTTC TGGTCCCCTC CCTGCTCCAC 
ACTGAGACCA CTGAGAAGGG CTGTGTCCTT CTGAGCTACC TGAATGAGAC AGTGACTGTA 
AGTGCTTCCT TGGAGTCTGT CAGGGGAAAC AGGAGCCTCT TCACTGACCT GGAGGCGGAG 
AATGACGTAC TCCACTGTGT CGCCTTCGCT GTCCCAAAGT CTTCATCCAA TGAGGAGGTA 
ATGTTCCTCA CTGTCCAAGT GAAAGGACCA ACCCAAGAAT TTAAGAAGCG GACCACAGTG 
ATGGTTAAGA ACGAGGACAG TCTGGTCTTT GTCCAGACAG ACAAATCAAT CTACAAACCA 
GGGCAGACAG TGAAATTTCG TGTTGTCTCC ATGGATGAAA ACTTTCACCC CCTGAATGAG 
TTGATTCCAC TAGTATACAT TCAGGATCCC AAAGGAAATC GCATCGCACA ATGGCAGAGT 
TTCCAGTTAG AGGGTGGCCT CAAGCAATTT TCTTTTCCCC TCTCATCAGA GCCCTTCCAG 
GGCTCCTACA AGGTGGTGGT ACAGAAGAAA TCAGGTGGAA GGACAGAGCA CCCTTTCACC 
GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA GTACAAGTAA CAGTGCCAAA GATAATCACC 
ATCTTGGAAG AAGAGATGAA TGTATCAGTG TGTGGCCTAT ACACATATGG GAAGCCTGTC 
CCTGGACATG TGACTGTGAG CATTTGCAGA AAGTATAGTG ACGCTTCCGA CTGCCACGGT 
GAAGATTCAC AGGCTTTCTG TGAGAAATTC AGTGGACAGC TAAACAGCCA TGGCTGCTTC 
TATCAGCAAG TAAAAACCAA GGTCTTCCAG CTGAAGAGGA AGGAGTATGA AATGAAACTT 
CACACTGAGG CCCAGATCCA AGAAGAAGGA ACAGTGGTGG AATTGACTGG AAGGCAGTCC 
AGTGAAATCA CAAGAACCAT AACCAAACTC TCATTTGTGA AAGTGGACTC ACACTTTCGA 
CAGGGAATTC CCTTCTTTGG GCAGGTGCGC CTAGTAGATG GGAAAGGCGT CCCTATACCA 
AATAAAGTCA TATTCATCAG AGGAAATGAA GCAAACTATT ACTCCAATGC TACCACGGAT 
GAGCATGGCC TTGTACAGTT CTCTATCAAC ACCACCAATG TTATGGGTAC CTCTCTTACT 
GTTAGGGTCA ATTACAAGGA TCGTAGTCCC TGTTACGGCT ACCAGTGGGT GTCAGAAGAA 
CACGAAGAGG CACATCACAC TGCTTATCTT GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC 
CTTGAGCCCA TGTCTCATGA ACTACCCTGT GGCCATACTC AGACAGTCCA GGCACATTAT 
ATTCTGAATG GAGGCACCCT GCTGGGGCTG AAGAAGCTCT CCTTCTATTA TCTGATAATG 
GCAAAGGGAG GCATTGTCCG AACTGGGACT CATGGACTGC TTGTGAAGCA GGAAGACATG 
AAGGGCCATT TTTCCATCTC AATCCCTGTG AAGTCAGACA TTGCTCCTGT CGCTCGGTTG 
CTCATCTATG CTGTTTTACC TACCGGGGAC GTGATTGGGG ATTCTGCAAA ATATGATGTT 
GAAAATTGTC TGGCCAACAA GGTGGATTTG AGCTTCAGCC CATCACAAAG TCTCCCAGCC 
TCACACGCCC ACCTGCGAGT CACAGCGGCT CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG 
GACCAAAGCG TGCTGCTCAT GAAGCCTGAT GCTGAGCTCT CGGCGTCCTC GGTTTACAAC 
CTGCTACCAG AAAAGGACCT CACTGGCTTC CCTGGGCCTT TGAATGACCA GGACGATGAA 
GACTGCATCA ATCGTCATAA TGTCTATATT AATGGAATCA CATATACTCC AGTATCAAGT 
ACAAATGAAA AGGATATGTA CAGCTTCCTA GAGGACATGG GCTTAAAGGC ATTCACCAAC 
TCAAAGATTC GTAAACCCAA AATGTGTCCA CAGCTTCAAC AGTATGAAAT GCATGGACCT 
GAAGGTCTAC GTGTAGGTTT TTATGAGTCA GATGTAATGG GAAGAGGCCA TGCACGCCTG 
GTGCATGTTG AAGAGCCTCA CACGGAGACC GTACGAAAGT ACTTCCCTGA GACATGGATC 
TGGGATTTGG TGGTGGTAAA CTCAGCAGGT GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC 
ACCATCACCG AGTGGAAGGC AGGGGCCTTC TGCCTGTCTG AAGATGCTGG ACTTGGTATC 
TCTTCCACTG CCTCTCTCCG AGCCTTCCAG CCCTTCTTTG TGGAGCTCAC AATGCCTTAC 
TCTGTGATTC GTGGAGAGGC CTTCACACTC AAGGCCACGG TCCTAAACTA CCTTCCCAAA 
TGCATCCGGG TCAGTGTGCA GCTGGAAGCC TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG 
AAGGAACAAG CGCCTCACTG CATCTGTGCA AACGGGCGGC AAACTGTGTC CTGGGCAGTA 
ACCCCAAAGT CATTAGGAAA TGTGAATTTC ACTGTGAGCG CAGAGGCACT AGAGTCTCAA 
GAGCTGTGTG GGACTGAGGT GCCTTCAGTT CCTGAACACG GAAGGAAAGA CACAGTCATC 
AAGCCTCTGT TGGTTGAACC TGAAGGACTA GAGAAGGAAA CAACATTCAA CTCCCTACTT 
TGTCCATCAG GTGGTGAGGT TTCTGAAGAA TTATCCCTGA AACTGCCACC AAATGTGGTA 
GAAGAATCTG CCCGAGCTTC TGTCTCAGTT TTGGGAGACA TATTAGGCTC TGCCATGCAA 
AACACACAAA ATCTTCTCCA GATGCCCTAT GGCTGTGGAG AGCAGAATAT GGTCCTCTTT 
GCTCCTAACA TCTATGTACT GGATTATCTA AATGAAACAC AGCAGCTTAC TCCAGAGATC 
AAGTCCAAGG CCATTGGCTA TCTCAACACT GGTTACCAGA GACAGTTGAA CTACAAACAC 
TATGATGGCT CCTACAGCAC CTTTGGGGAG CGATATGGCA GGAACCAGGG CAACACCTGG 
CTCACAGCCT TTGTTCTGAA GACTTTTGCC CAAGCTCGAG CCTACATCTT CATCGATGAA 
GCACACATTA CCCAAGCCCT CATATGGCTC TCCCAGAGGC AGAAGGACAA TGGCTGTTTC 
AGGAGCTCTG GGTCACTGCT CAACAATGCC ATAAAGGGAG GAGTAGAAGA TGAAGTGACC 
CTCTCCGCCT ATATCACCAT CGCCCTTCTG GAGATTCCTC TCACAGTCAC TCACCCTGTT 
GTCCGCAATG CCCTGTTTTG CCTGGAGTCA GCCTGGAAGA CAGCACAAGA AGGGGACCAT 
GGCAGCCATG TATATACCAA AGCACTGCTG GCCTATGCTT TTGCCCTGGC AGGTAACCAG 
GACAAGAGGA AGGAAGTACT CAAGTCACTT AATGAGGAAG CTGTGAAGAA AGACAACTCT 
GTCCATTGGG AGCGCCCTCA GAAACCCAAG GCACCAGTGG GGCATTTTTA CGAACCCCAG 
GCTCCCTCTG CTGAGGTGGA GATGACATCC TATGTGCTCC TCGCTTATCT CACGGCCCAG 
CCAGCCCCAA CCTCGGAGGA CCTGACCTCT GCAACCAACA TCGTGAAGTG GATCACGAAG 
CAGCAGAATG CCCAGGGCGG TTTCTCCTCC ACCCAGGACA CAGTGGTGGC TCTCCATGCT 
CTGTCCAAAT ATGGAGCAGC CACATTTACC AGGACTGGGA AGGCTGCACA GGTGACTATC 
CAGTCTTCAG GGACATTTTC CAGCAAATTC CAAGTGGACA ACAACAACCG CCTGTTACTG 
CAGCAGGTCT CATTGCCAGA GCTGCCTGGG GAATACAGCA TGAAAGTGAC AGGAGAAGGA 
TGTGTCTACC TCCAGACATC CTTGAAATAC AATATTCTCC CAGAAAAGGA AGAGTTCCCC 
TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA ACTTGTGATG AACCCAAAGC CCACACCAGC 
TTCCAAATCT CCCTAAGTGT CAGTTACACA GGGAGCCGCT CTGCCTCCAA CATGGCGATC 
GTTGATGTGA AGATGGTCTC TGGCTTCATT CCCCTGAAGC CAACAGTGAA AATGCTTGAA 
AGATCTAACC ATGTGAGCCG GACAGAAGTC AGCAGCAACC ATGTCTTGAT TTACCTTGAT 
AAGGTGTCAA ATCAGACACT GAGCTTGTTC TTCACGGTTC TGCAAGATGT CCCAGTAAGA 
GATCTGAAAC CAGCCATAGT GAAAGTCTAT GATTACTACG AGACGGATGA GTTTGCAATT 
GCTGAGTACA ATGCTCCTTG CAGCAAAGAT CTTGGAAATG CTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

A2M ( XM_006719056.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006719119.1 Homo sapiens alpha-2-macroglobulin (A2M), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu46081
Clone ID Related Accession (Same CDS sequence)	XM_006719056.3 , XM_006719056.2
Accession Version	XM_006719056.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4539bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	alpha-2-macroglobulin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006719056.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAAGA ACAAACTCCT TCATCCAAGT CTGGTTCTTC TCCTCTTGGT CCTCCTGCCC 
ACAGACGCCT CAGTCTCTGG AAAACCGCAG TATATGGTTC TGGTCCCCTC CCTGCTCCAC 
ACTGAGACCA CTGAGAAGGG CTGTGTCCTT CTGAGCTACC TGAATGAGAC AGTGACTGTA 
AGTGCTTCCT TGGAGTCTGT CAGGGGAAAC AGGAGCCTCT TCACTGACCT GGAGGCGGAG 
AATGACGTAC TCCACTGTGT CGCCTTCGCT GTCCCAAAGT CTTCATCCAA TGAGGAGGTA 
ATGTTCCTCA CTGTCCAAGT GAAAGGACCA ACCCAAGAAT TTAAGAAGCG GACCACAGTG 
ATGGTTAAGA ACGAGGACAG TCTGGTCTTT GTCCAGACAG ACAAATCAAT CTACAAACCA 
GGGCAGACAG TGAAATTTCG TGTTGTCTCC ATGGATGAAA ACTTTCACCC CCTGAATGAG 
TTGATTCCAC TAGTATACAT TCAGGATCCC AAAGGAAATC GCATCGCACA ATGGCAGAGT 
TTCCAGTTAG AGGGTGGCCT CAAGCAATTT TCTTTTCCCC TCTCATCAGA GCCCTTCCAG 
GGCTCCTACA AGGTGGTGGT ACAGAAGAAA TCAGGTGGAA GGACAGAGCA CCCTTTCACC 
GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA GTACAAGTAA CAGTGCCAAA GATAATCACC 
ATCTTGGAAG AAGAGATGAA TGTATCAGTG TGTGGCCTAT ACACATATGG GAAGCCTGTC 
CCTGGACATG TGACTGTGAG CATTTGCAGA AAGTATAGTG ACGCTTCCGA CTGCCACGGT 
GAAGATTCAC AGGCTTTCTG TGAGAAATTC AGTGGACAGC TAAACAGCCA TGGCTGCTTC 
TATCAGCAAG TAAAAACCAA GGTCTTCCAG CTGAAGAGGA AGGAGTATGA AATGAAACTT 
CACACTGAGG CCCAGATCCA AGAAGAAGGA ACAGTGGTGG AATTGACTGG AAGGCAGTCC 
AGTGAAATCA CAAGAACCAT AACCAAACTC TCATTTGTGA AAGTGGACTC ACACTTTCGA 
CAGGGAATTC CCTTCTTTGG GCAGGTGCGC CTAGTAGATG GGAAAGGCGT CCCTATACCA 
AATAAAGTCA TATTCATCAG AGGAAATGAA GCAAACTATT ACTCCAATGC TACCACGGAT 
GAGCATGGCC TTGTACAGTT CTCTATCAAC ACCACCAATG TTATGGGTAC CTCTCTTACT 
GTTAGGGTCA ATTACAAGGA TCGTAGTCCC TGTTACGGCT ACCAGTGGGT GTCAGAAGAA 
CACGAAGAGG CACATCACAC TGCTTATCTT GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC 
CTTGAGCCCA TGTCTCATGA ACTACCCTGT GGCCATACTC AGACAGTCCA GGCACATTAT 
ATTCTGAATG GAGGCACCCT GCTGGGGCTG AAGAAGCTCT CCTTCTATTA TCTGATAATG 
GCAAAGGGAG GCATTGTCCG AACTGGGACT CATGGACTGC TTGTGAAGCA GGAAGACATG 
AAGGGCCATT TTTCCATCTC AATCCCTGTG AAGTCAGACA TTGCTCCTGT CGCTCGGTTG 
CTCATCTATG CTGTTTTACC TACCGGGGAC GTGATTGGGG ATTCTGCAAA ATATGATGTT 
GAAAATTGTC TGGCCAACAA GGTGGATTTG AGCTTCAGCC CATCACAAAG TCTCCCAGCC 
TCACACGCCC ACCTGCGAGT CACAGCGGCT CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG 
GACCAAAGCG TGCTGCTCAT GAAGCCTGAT GCTGAGCTCT CGGCGTCCTC GGTTTACAAC 
CTGCTACCAG AAAAGGACCT CACTGGCTTC CCTGGGCCTT TGAATGACCA GGACAATGAA 
GACTGCATCA ATCGTCATAA TGTCTATATT AATGGAATCA CATATACTCC AGTATCAAGT 
ACAAATGAAA AGGATATGTA CAGCTTCCTA GAGGACATGG GCTTAAAGGC ATTCACCAAC 
TCAAAGATTC GTAAACCCAA AATGTGTCCA CAGCTTCAAC AGTATGAAAT GCATGGACCT 
GAAGGTCTAC GTGTAGGTTT TTATGAGTCA GATGTAATGG GAAGAGGCCA TGCACGCCTG 
GTGCATGTTG AAGAGCCTCA CACGGAGACC GTACGAAAGT ACTTCCCTGA GACATGGATC 
TGGGATTTGG TGGTGGTAAA CTCAGCAGGT GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC 
ACCATCACCG AGTGGAAGGC AGGGGCCTTC TGCCTGTCTG AAGATGCTGG ACTTGGTATC 
TCTTCCACTG CCTCTCTCCG AGCCTTCCAG CCCTTCTTTG TGGAGCTCAC AATGCCTTAC 
TCTGTGATTC GTGGAGAGGC CTTCACACTC AAGGCCACGG TCCTAAACTA CCTTCCCAAA 
TGCATCCGGG TCAGTGTGCA GCTGGAAGCC TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG 
AAGGAACAAG CGCCTCACTG CATCTGTGCA AACGGGCGGC AAACTGTGTC CTGGGCAGTA 
ACCCCAAAGT CATTAGGAAA TGTGAATTTC ACTGTGAGCG CAGAGGCACT AGAGTCTCAA 
GAGCTGTGTG GGACTGAGGT GCCTTCAGTT CCTGAACACG GAAGGAAAGA CACAGTCATC 
AAGCCTCTGT TGGTTGAACC TGAAGGACTA GAGAAGGAAA CAACATTCAA CTCCCTACTT 
TGTCCATCAG GTGGTGAGGT TTCTGAAGAA TTATCCCTGA AACTGCCACC AAATGTGGTA 
GAAGAATCTG CCCGAGCTTC TGTCTCAGTT TTGGGAGACA TATTAGGCTC TGCCATGCAA 
AACACACAAA ATCTTCTCCA GATGCCCTAT GGCTGTGGAG AGCAGAATAT GGTCCTCTTT 
GCTCCTAACA TCTATGTACT GGATTATCTA AATGAAACAC AGCAGCTTAC TCCAGAGATC 
AAGTCCAAGG CCATTGGCTA TCTCAACACT GGTTACCAGA GACAGTTGAA CTACAAACAC 
TATGATGGCT CCTACAGCAC CTTTGGGGAG CGATATGGCA GGAACCAGGG CAACACCTGG 
CTCACAGCCT TTGTTCTGAA GACTTTTGCC CAAGCTCGAG CCTACATCTT CATCGATGAA 
GCACACATTA CCCAAGCCCT CATATGGCTC TCCCAGAGGC AGAAGGACAA TGGCTGTTTC 
AGGAGCTCTG GGTCACTGCT CAACAATGCC ATAAAGGGAG GAGTAGAAGA TGAAGTGACC 
CTCTCCGCCT ATATCACCAT CGCCCTTCTG GAGATTCCTC TCACAGTCAC TCACCCTGTT 
GTCCGCAATG CCCTGTTTTG CCTGGAGTCA GCCTGGAAGA CAGCACAAGA AGGGGACCAT 
GGCAGCCATG TATATACCAA AGCACTGCTG GCCTATGCTT TTGCCCTGGC AGGTAACCAG 
GACAAGAGGA AGGAAGTACT CAAGTCACTT AATGAGGAAG CTGTGAAGAA AGACAACTCT 
GTCCATTGGG AGCGCCCTCA GAAACCCAAG GCACCAGTGG GGCATTTTTA CGAACCCCAG 
GCTCCCTCTG CTGAGGTGGA GATGACATCC TATGTGCTCC TCGCTTATCT CACGGCCCAG 
CCAGCCCCAA CCTCGGAGGA CCTGACCTCT GCAACCAACA TCGTGAAGTG GATCACGAAG 
CAGCAGAATG CCCAGGGCGG TTTCTCCTCC ACCCAGGACA CAGTGGTGGC TCTCCATGCT 
CTGTCCAAAT ATGGAGCAGC CACATTTACC AGGACTGGGA AGGCTGCACA GGTGACTATC 
CAGTCTTCAG GGACATTTTC CAGCAAATTC CAAGTGGACA ACAACAACCG CCTGTTACTG 
CAGCAGGTCT CATTGCCAGA GCTGCCTGGG GAATACAGCA TGAAAGTGAC AGGAGAAGGA 
TGTGTCTACC TCCAGACATC CTTGAAATAC AATATTCTCC CAGAAAAGGA AGAGTTCCCC 
TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA ACTTGTGATG AACCCAAAGC CCACACCAGC 
TTCCAAATCT CCCTAAGTGT CAGTTACACA GGGAGCCGCT CTGCCTCCAA CATGGCGATC 
GTTGATGTGA AGATGGTCTC TGGCTTCATT CCCCTGAAGC CAACAGTGAA AATGCTTGAA 
AGATCTAACC ATGTGAGCCG GACAGAAGTC AGCAGCAACC ATGTCTTGAT TTACCTTGAT 
AAGGTGTCAA ATCAGACACT GAGCTTGTTC TTCACGGTTC TGCAAGATGT CCCAGTAAGA 
GATCTGAAAC CAGCCATAGT GAAAGTCTAT GATTACTACG AGACGGATGA GTTTGCAATT 
GCTGAGTACA ATGCTCCTTG CAGCAAAGGT AAGCCACTCA CACTCCTCCA AAAGGCAGTC 
AGAGCTCCTT CAGCTTGCCC CCCAAACCTT CTCCTTCATA AAACGCTGGG TAAATATTTG 
TCAAAAACAT CAAATTACTC ACACTGCACA TTATTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006719119.1
CDS	100..4638
Translation	MGKNKLLHPSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDNEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAPCSKGKPLTLLQKAVRAPSACPPNLLLHKTLGKYLSKTSNYSHCTLL

Target ORF information:

RefSeq Version	XM_006719056.3
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006719056.3

ORF Insert Sequence:

ATGGGGAAGA ACAAACTCCT TCATCCAAGT CTGGTTCTTC TCCTCTTGGT CCTCCTGCCC 
ACAGACGCCT CAGTCTCTGG AAAACCGCAG TATATGGTTC TGGTCCCCTC CCTGCTCCAC 
ACTGAGACCA CTGAGAAGGG CTGTGTCCTT CTGAGCTACC TGAATGAGAC AGTGACTGTA 
AGTGCTTCCT TGGAGTCTGT CAGGGGAAAC AGGAGCCTCT TCACTGACCT GGAGGCGGAG 
AATGACGTAC TCCACTGTGT CGCCTTCGCT GTCCCAAAGT CTTCATCCAA TGAGGAGGTA 
ATGTTCCTCA CTGTCCAAGT GAAAGGACCA ACCCAAGAAT TTAAGAAGCG GACCACAGTG 
ATGGTTAAGA ACGAGGACAG TCTGGTCTTT GTCCAGACAG ACAAATCAAT CTACAAACCA 
GGGCAGACAG TGAAATTTCG TGTTGTCTCC ATGGATGAAA ACTTTCACCC CCTGAATGAG 
TTGATTCCAC TAGTATACAT TCAGGATCCC AAAGGAAATC GCATCGCACA ATGGCAGAGT 
TTCCAGTTAG AGGGTGGCCT CAAGCAATTT TCTTTTCCCC TCTCATCAGA GCCCTTCCAG 
GGCTCCTACA AGGTGGTGGT ACAGAAGAAA TCAGGTGGAA GGACAGAGCA CCCTTTCACC 
GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA GTACAAGTAA CAGTGCCAAA GATAATCACC 
ATCTTGGAAG AAGAGATGAA TGTATCAGTG TGTGGCCTAT ACACATATGG GAAGCCTGTC 
CCTGGACATG TGACTGTGAG CATTTGCAGA AAGTATAGTG ACGCTTCCGA CTGCCACGGT 
GAAGATTCAC AGGCTTTCTG TGAGAAATTC AGTGGACAGC TAAACAGCCA TGGCTGCTTC 
TATCAGCAAG TAAAAACCAA GGTCTTCCAG CTGAAGAGGA AGGAGTATGA AATGAAACTT 
CACACTGAGG CCCAGATCCA AGAAGAAGGA ACAGTGGTGG AATTGACTGG AAGGCAGTCC 
AGTGAAATCA CAAGAACCAT AACCAAACTC TCATTTGTGA AAGTGGACTC ACACTTTCGA 
CAGGGAATTC CCTTCTTTGG GCAGGTGCGC CTAGTAGATG GGAAAGGCGT CCCTATACCA 
AATAAAGTCA TATTCATCAG AGGAAATGAA GCAAACTATT ACTCCAATGC TACCACGGAT 
GAGCATGGCC TTGTACAGTT CTCTATCAAC ACCACCAATG TTATGGGTAC CTCTCTTACT 
GTTAGGGTCA ATTACAAGGA TCGTAGTCCC TGTTACGGCT ACCAGTGGGT GTCAGAAGAA 
CACGAAGAGG CACATCACAC TGCTTATCTT GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC 
CTTGAGCCCA TGTCTCATGA ACTACCCTGT GGCCATACTC AGACAGTCCA GGCACATTAT 
ATTCTGAATG GAGGCACCCT GCTGGGGCTG AAGAAGCTCT CCTTCTATTA TCTGATAATG 
GCAAAGGGAG GCATTGTCCG AACTGGGACT CATGGACTGC TTGTGAAGCA GGAAGACATG 
AAGGGCCATT TTTCCATCTC AATCCCTGTG AAGTCAGACA TTGCTCCTGT CGCTCGGTTG 
CTCATCTATG CTGTTTTACC TACCGGGGAC GTGATTGGGG ATTCTGCAAA ATATGATGTT 
GAAAATTGTC TGGCCAACAA GGTGGATTTG AGCTTCAGCC CATCACAAAG TCTCCCAGCC 
TCACACGCCC ACCTGCGAGT CACAGCGGCT CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG 
GACCAAAGCG TGCTGCTCAT GAAGCCTGAT GCTGAGCTCT CGGCGTCCTC GGTTTACAAC 
CTGCTACCAG AAAAGGACCT CACTGGCTTC CCTGGGCCTT TGAATGACCA GGACAATGAA 
GACTGCATCA ATCGTCATAA TGTCTATATT AATGGAATCA CATATACTCC AGTATCAAGT 
ACAAATGAAA AGGATATGTA CAGCTTCCTA GAGGACATGG GCTTAAAGGC ATTCACCAAC 
TCAAAGATTC GTAAACCCAA AATGTGTCCA CAGCTTCAAC AGTATGAAAT GCATGGACCT 
GAAGGTCTAC GTGTAGGTTT TTATGAGTCA GATGTAATGG GAAGAGGCCA TGCACGCCTG 
GTGCATGTTG AAGAGCCTCA CACGGAGACC GTACGAAAGT ACTTCCCTGA GACATGGATC 
TGGGATTTGG TGGTGGTAAA CTCAGCAGGT GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC 
ACCATCACCG AGTGGAAGGC AGGGGCCTTC TGCCTGTCTG AAGATGCTGG ACTTGGTATC 
TCTTCCACTG CCTCTCTCCG AGCCTTCCAG CCCTTCTTTG TGGAGCTCAC AATGCCTTAC 
TCTGTGATTC GTGGAGAGGC CTTCACACTC AAGGCCACGG TCCTAAACTA CCTTCCCAAA 
TGCATCCGGG TCAGTGTGCA GCTGGAAGCC TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG 
AAGGAACAAG CGCCTCACTG CATCTGTGCA AACGGGCGGC AAACTGTGTC CTGGGCAGTA 
ACCCCAAAGT CATTAGGAAA TGTGAATTTC ACTGTGAGCG CAGAGGCACT AGAGTCTCAA 
GAGCTGTGTG GGACTGAGGT GCCTTCAGTT CCTGAACACG GAAGGAAAGA CACAGTCATC 
AAGCCTCTGT TGGTTGAACC TGAAGGACTA GAGAAGGAAA CAACATTCAA CTCCCTACTT 
TGTCCATCAG GTGGTGAGGT TTCTGAAGAA TTATCCCTGA AACTGCCACC AAATGTGGTA 
GAAGAATCTG CCCGAGCTTC TGTCTCAGTT TTGGGAGACA TATTAGGCTC TGCCATGCAA 
AACACACAAA ATCTTCTCCA GATGCCCTAT GGCTGTGGAG AGCAGAATAT GGTCCTCTTT 
GCTCCTAACA TCTATGTACT GGATTATCTA AATGAAACAC AGCAGCTTAC TCCAGAGATC 
AAGTCCAAGG CCATTGGCTA TCTCAACACT GGTTACCAGA GACAGTTGAA CTACAAACAC 
TATGATGGCT CCTACAGCAC CTTTGGGGAG CGATATGGCA GGAACCAGGG CAACACCTGG 
CTCACAGCCT TTGTTCTGAA GACTTTTGCC CAAGCTCGAG CCTACATCTT CATCGATGAA 
GCACACATTA CCCAAGCCCT CATATGGCTC TCCCAGAGGC AGAAGGACAA TGGCTGTTTC 
AGGAGCTCTG GGTCACTGCT CAACAATGCC ATAAAGGGAG GAGTAGAAGA TGAAGTGACC 
CTCTCCGCCT ATATCACCAT CGCCCTTCTG GAGATTCCTC TCACAGTCAC TCACCCTGTT 
GTCCGCAATG CCCTGTTTTG CCTGGAGTCA GCCTGGAAGA CAGCACAAGA AGGGGACCAT 
GGCAGCCATG TATATACCAA AGCACTGCTG GCCTATGCTT TTGCCCTGGC AGGTAACCAG 
GACAAGAGGA AGGAAGTACT CAAGTCACTT AATGAGGAAG CTGTGAAGAA AGACAACTCT 
GTCCATTGGG AGCGCCCTCA GAAACCCAAG GCACCAGTGG GGCATTTTTA CGAACCCCAG 
GCTCCCTCTG CTGAGGTGGA GATGACATCC TATGTGCTCC TCGCTTATCT CACGGCCCAG 
CCAGCCCCAA CCTCGGAGGA CCTGACCTCT GCAACCAACA TCGTGAAGTG GATCACGAAG 
CAGCAGAATG CCCAGGGCGG TTTCTCCTCC ACCCAGGACA CAGTGGTGGC TCTCCATGCT 
CTGTCCAAAT ATGGAGCAGC CACATTTACC AGGACTGGGA AGGCTGCACA GGTGACTATC 
CAGTCTTCAG GGACATTTTC CAGCAAATTC CAAGTGGACA ACAACAACCG CCTGTTACTG 
CAGCAGGTCT CATTGCCAGA GCTGCCTGGG GAATACAGCA TGAAAGTGAC AGGAGAAGGA 
TGTGTCTACC TCCAGACATC CTTGAAATAC AATATTCTCC CAGAAAAGGA AGAGTTCCCC 
TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA ACTTGTGATG AACCCAAAGC CCACACCAGC 
TTCCAAATCT CCCTAAGTGT CAGTTACACA GGGAGCCGCT CTGCCTCCAA CATGGCGATC 
GTTGATGTGA AGATGGTCTC TGGCTTCATT CCCCTGAAGC CAACAGTGAA AATGCTTGAA 
AGATCTAACC ATGTGAGCCG GACAGAAGTC AGCAGCAACC ATGTCTTGAT TTACCTTGAT 
AAGGTGTCAA ATCAGACACT GAGCTTGTTC TTCACGGTTC TGCAAGATGT CCCAGTAAGA 
GATCTGAAAC CAGCCATAGT GAAAGTCTAT GATTACTACG AGACGGATGA GTTTGCAATT 
GCTGAGTACA ATGCTCCTTG CAGCAAAGGT AAGCCACTCA CACTCCTCCA AAAGGCAGTC 
AGAGCTCCTT CAGCTTGCCC CCCAAACCTT CTCCTTCATA AAACGCTGGG TAAATATTTG 
TCAAAAACAT CAAATTACTC ACACTGCACA TTATTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

A2M ( XM_006719056.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006719119.1 Homo sapiens alpha-2-macroglobulin (A2M), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu46081
Clone ID Related Accession (Same CDS sequence)	XM_006719056.3 , XM_006719056.2
Accession Version	XM_006719056.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4539bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	alpha-2-macroglobulin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_006719056.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGAAGA ACAAACTCCT TCATCCAAGT CTGGTTCTTC TCCTCTTGGT CCTCCTGCCC 
ACAGACGCCT CAGTCTCTGG AAAACCGCAG TATATGGTTC TGGTCCCCTC CCTGCTCCAC 
ACTGAGACCA CTGAGAAGGG CTGTGTCCTT CTGAGCTACC TGAATGAGAC AGTGACTGTA 
AGTGCTTCCT TGGAGTCTGT CAGGGGAAAC AGGAGCCTCT TCACTGACCT GGAGGCGGAG 
AATGACGTAC TCCACTGTGT CGCCTTCGCT GTCCCAAAGT CTTCATCCAA TGAGGAGGTA 
ATGTTCCTCA CTGTCCAAGT GAAAGGACCA ACCCAAGAAT TTAAGAAGCG GACCACAGTG 
ATGGTTAAGA ACGAGGACAG TCTGGTCTTT GTCCAGACAG ACAAATCAAT CTACAAACCA 
GGGCAGACAG TGAAATTTCG TGTTGTCTCC ATGGATGAAA ACTTTCACCC CCTGAATGAG 
TTGATTCCAC TAGTATACAT TCAGGATCCC AAAGGAAATC GCATCGCACA ATGGCAGAGT 
TTCCAGTTAG AGGGTGGCCT CAAGCAATTT TCTTTTCCCC TCTCATCAGA GCCCTTCCAG 
GGCTCCTACA AGGTGGTGGT ACAGAAGAAA TCAGGTGGAA GGACAGAGCA CCCTTTCACC 
GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA GTACAAGTAA CAGTGCCAAA GATAATCACC 
ATCTTGGAAG AAGAGATGAA TGTATCAGTG TGTGGCCTAT ACACATATGG GAAGCCTGTC 
CCTGGACATG TGACTGTGAG CATTTGCAGA AAGTATAGTG ACGCTTCCGA CTGCCACGGT 
GAAGATTCAC AGGCTTTCTG TGAGAAATTC AGTGGACAGC TAAACAGCCA TGGCTGCTTC 
TATCAGCAAG TAAAAACCAA GGTCTTCCAG CTGAAGAGGA AGGAGTATGA AATGAAACTT 
CACACTGAGG CCCAGATCCA AGAAGAAGGA ACAGTGGTGG AATTGACTGG AAGGCAGTCC 
AGTGAAATCA CAAGAACCAT AACCAAACTC TCATTTGTGA AAGTGGACTC ACACTTTCGA 
CAGGGAATTC CCTTCTTTGG GCAGGTGCGC CTAGTAGATG GGAAAGGCGT CCCTATACCA 
AATAAAGTCA TATTCATCAG AGGAAATGAA GCAAACTATT ACTCCAATGC TACCACGGAT 
GAGCATGGCC TTGTACAGTT CTCTATCAAC ACCACCAATG TTATGGGTAC CTCTCTTACT 
GTTAGGGTCA ATTACAAGGA TCGTAGTCCC TGTTACGGCT ACCAGTGGGT GTCAGAAGAA 
CACGAAGAGG CACATCACAC TGCTTATCTT GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC 
CTTGAGCCCA TGTCTCATGA ACTACCCTGT GGCCATACTC AGACAGTCCA GGCACATTAT 
ATTCTGAATG GAGGCACCCT GCTGGGGCTG AAGAAGCTCT CCTTCTATTA TCTGATAATG 
GCAAAGGGAG GCATTGTCCG AACTGGGACT CATGGACTGC TTGTGAAGCA GGAAGACATG 
AAGGGCCATT TTTCCATCTC AATCCCTGTG AAGTCAGACA TTGCTCCTGT CGCTCGGTTG 
CTCATCTATG CTGTTTTACC TACCGGGGAC GTGATTGGGG ATTCTGCAAA ATATGATGTT 
GAAAATTGTC TGGCCAACAA GGTGGATTTG AGCTTCAGCC CATCACAAAG TCTCCCAGCC 
TCACACGCCC ACCTGCGAGT CACAGCGGCT CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG 
GACCAAAGCG TGCTGCTCAT GAAGCCTGAT GCTGAGCTCT CGGCGTCCTC GGTTTACAAC 
CTGCTACCAG AAAAGGACCT CACTGGCTTC CCTGGGCCTT TGAATGACCA GGACAATGAA 
GACTGCATCA ATCGTCATAA TGTCTATATT AATGGAATCA CATATACTCC AGTATCAAGT 
ACAAATGAAA AGGATATGTA CAGCTTCCTA GAGGACATGG GCTTAAAGGC ATTCACCAAC 
TCAAAGATTC GTAAACCCAA AATGTGTCCA CAGCTTCAAC AGTATGAAAT GCATGGACCT 
GAAGGTCTAC GTGTAGGTTT TTATGAGTCA GATGTAATGG GAAGAGGCCA TGCACGCCTG 
GTGCATGTTG AAGAGCCTCA CACGGAGACC GTACGAAAGT ACTTCCCTGA GACATGGATC 
TGGGATTTGG TGGTGGTAAA CTCAGCAGGT GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC 
ACCATCACCG AGTGGAAGGC AGGGGCCTTC TGCCTGTCTG AAGATGCTGG ACTTGGTATC 
TCTTCCACTG CCTCTCTCCG AGCCTTCCAG CCCTTCTTTG TGGAGCTCAC AATGCCTTAC 
TCTGTGATTC GTGGAGAGGC CTTCACACTC AAGGCCACGG TCCTAAACTA CCTTCCCAAA 
TGCATCCGGG TCAGTGTGCA GCTGGAAGCC TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG 
AAGGAACAAG CGCCTCACTG CATCTGTGCA AACGGGCGGC AAACTGTGTC CTGGGCAGTA 
ACCCCAAAGT CATTAGGAAA TGTGAATTTC ACTGTGAGCG CAGAGGCACT AGAGTCTCAA 
GAGCTGTGTG GGACTGAGGT GCCTTCAGTT CCTGAACACG GAAGGAAAGA CACAGTCATC 
AAGCCTCTGT TGGTTGAACC TGAAGGACTA GAGAAGGAAA CAACATTCAA CTCCCTACTT 
TGTCCATCAG GTGGTGAGGT TTCTGAAGAA TTATCCCTGA AACTGCCACC AAATGTGGTA 
GAAGAATCTG CCCGAGCTTC TGTCTCAGTT TTGGGAGACA TATTAGGCTC TGCCATGCAA 
AACACACAAA ATCTTCTCCA GATGCCCTAT GGCTGTGGAG AGCAGAATAT GGTCCTCTTT 
GCTCCTAACA TCTATGTACT GGATTATCTA AATGAAACAC AGCAGCTTAC TCCAGAGATC 
AAGTCCAAGG CCATTGGCTA TCTCAACACT GGTTACCAGA GACAGTTGAA CTACAAACAC 
TATGATGGCT CCTACAGCAC CTTTGGGGAG CGATATGGCA GGAACCAGGG CAACACCTGG 
CTCACAGCCT TTGTTCTGAA GACTTTTGCC CAAGCTCGAG CCTACATCTT CATCGATGAA 
GCACACATTA CCCAAGCCCT CATATGGCTC TCCCAGAGGC AGAAGGACAA TGGCTGTTTC 
AGGAGCTCTG GGTCACTGCT CAACAATGCC ATAAAGGGAG GAGTAGAAGA TGAAGTGACC 
CTCTCCGCCT ATATCACCAT CGCCCTTCTG GAGATTCCTC TCACAGTCAC TCACCCTGTT 
GTCCGCAATG CCCTGTTTTG CCTGGAGTCA GCCTGGAAGA CAGCACAAGA AGGGGACCAT 
GGCAGCCATG TATATACCAA AGCACTGCTG GCCTATGCTT TTGCCCTGGC AGGTAACCAG 
GACAAGAGGA AGGAAGTACT CAAGTCACTT AATGAGGAAG CTGTGAAGAA AGACAACTCT 
GTCCATTGGG AGCGCCCTCA GAAACCCAAG GCACCAGTGG GGCATTTTTA CGAACCCCAG 
GCTCCCTCTG CTGAGGTGGA GATGACATCC TATGTGCTCC TCGCTTATCT CACGGCCCAG 
CCAGCCCCAA CCTCGGAGGA CCTGACCTCT GCAACCAACA TCGTGAAGTG GATCACGAAG 
CAGCAGAATG CCCAGGGCGG TTTCTCCTCC ACCCAGGACA CAGTGGTGGC TCTCCATGCT 
CTGTCCAAAT ATGGAGCAGC CACATTTACC AGGACTGGGA AGGCTGCACA GGTGACTATC 
CAGTCTTCAG GGACATTTTC CAGCAAATTC CAAGTGGACA ACAACAACCG CCTGTTACTG 
CAGCAGGTCT CATTGCCAGA GCTGCCTGGG GAATACAGCA TGAAAGTGAC AGGAGAAGGA 
TGTGTCTACC TCCAGACATC CTTGAAATAC AATATTCTCC CAGAAAAGGA AGAGTTCCCC 
TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA ACTTGTGATG AACCCAAAGC CCACACCAGC 
TTCCAAATCT CCCTAAGTGT CAGTTACACA GGGAGCCGCT CTGCCTCCAA CATGGCGATC 
GTTGATGTGA AGATGGTCTC TGGCTTCATT CCCCTGAAGC CAACAGTGAA AATGCTTGAA 
AGATCTAACC ATGTGAGCCG GACAGAAGTC AGCAGCAACC ATGTCTTGAT TTACCTTGAT 
AAGGTGTCAA ATCAGACACT GAGCTTGTTC TTCACGGTTC TGCAAGATGT CCCAGTAAGA 
GATCTGAAAC CAGCCATAGT GAAAGTCTAT GATTACTACG AGACGGATGA GTTTGCAATT 
GCTGAGTACA ATGCTCCTTG CAGCAAAGGT AAGCCACTCA CACTCCTCCA AAAGGCAGTC 
AGAGCTCCTT CAGCTTGCCC CCCAAACCTT CTCCTTCATA AAACGCTGGG TAAATATTTG 
TCAAAAACAT CAAATTACTC ACACTGCACA TTATTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006719119.1
CDS	92..4630
Translation	MGKNKLLHPSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDNEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAPCSKGKPLTLLQKAVRAPSACPPNLLLHKTLGKYLSKTSNYSHCTLL

Target ORF information:

RefSeq Version	XM_006719056.2
Organism	Homo sapiens(human)
Definition	Homo sapiens alpha-2-macroglobulin (A2M), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006719056.2

ORF Insert Sequence:

ATGGGGAAGA ACAAACTCCT TCATCCAAGT CTGGTTCTTC TCCTCTTGGT CCTCCTGCCC 
ACAGACGCCT CAGTCTCTGG AAAACCGCAG TATATGGTTC TGGTCCCCTC CCTGCTCCAC 
ACTGAGACCA CTGAGAAGGG CTGTGTCCTT CTGAGCTACC TGAATGAGAC AGTGACTGTA 
AGTGCTTCCT TGGAGTCTGT CAGGGGAAAC AGGAGCCTCT TCACTGACCT GGAGGCGGAG 
AATGACGTAC TCCACTGTGT CGCCTTCGCT GTCCCAAAGT CTTCATCCAA TGAGGAGGTA 
ATGTTCCTCA CTGTCCAAGT GAAAGGACCA ACCCAAGAAT TTAAGAAGCG GACCACAGTG 
ATGGTTAAGA ACGAGGACAG TCTGGTCTTT GTCCAGACAG ACAAATCAAT CTACAAACCA 
GGGCAGACAG TGAAATTTCG TGTTGTCTCC ATGGATGAAA ACTTTCACCC CCTGAATGAG 
TTGATTCCAC TAGTATACAT TCAGGATCCC AAAGGAAATC GCATCGCACA ATGGCAGAGT 
TTCCAGTTAG AGGGTGGCCT CAAGCAATTT TCTTTTCCCC TCTCATCAGA GCCCTTCCAG 
GGCTCCTACA AGGTGGTGGT ACAGAAGAAA TCAGGTGGAA GGACAGAGCA CCCTTTCACC 
GTGGAGGAAT TTGTTCTTCC CAAGTTTGAA GTACAAGTAA CAGTGCCAAA GATAATCACC 
ATCTTGGAAG AAGAGATGAA TGTATCAGTG TGTGGCCTAT ACACATATGG GAAGCCTGTC 
CCTGGACATG TGACTGTGAG CATTTGCAGA AAGTATAGTG ACGCTTCCGA CTGCCACGGT 
GAAGATTCAC AGGCTTTCTG TGAGAAATTC AGTGGACAGC TAAACAGCCA TGGCTGCTTC 
TATCAGCAAG TAAAAACCAA GGTCTTCCAG CTGAAGAGGA AGGAGTATGA AATGAAACTT 
CACACTGAGG CCCAGATCCA AGAAGAAGGA ACAGTGGTGG AATTGACTGG AAGGCAGTCC 
AGTGAAATCA CAAGAACCAT AACCAAACTC TCATTTGTGA AAGTGGACTC ACACTTTCGA 
CAGGGAATTC CCTTCTTTGG GCAGGTGCGC CTAGTAGATG GGAAAGGCGT CCCTATACCA 
AATAAAGTCA TATTCATCAG AGGAAATGAA GCAAACTATT ACTCCAATGC TACCACGGAT 
GAGCATGGCC TTGTACAGTT CTCTATCAAC ACCACCAATG TTATGGGTAC CTCTCTTACT 
GTTAGGGTCA ATTACAAGGA TCGTAGTCCC TGTTACGGCT ACCAGTGGGT GTCAGAAGAA 
CACGAAGAGG CACATCACAC TGCTTATCTT GTGTTCTCCC CAAGCAAGAG CTTTGTCCAC 
CTTGAGCCCA TGTCTCATGA ACTACCCTGT GGCCATACTC AGACAGTCCA GGCACATTAT 
ATTCTGAATG GAGGCACCCT GCTGGGGCTG AAGAAGCTCT CCTTCTATTA TCTGATAATG 
GCAAAGGGAG GCATTGTCCG AACTGGGACT CATGGACTGC TTGTGAAGCA GGAAGACATG 
AAGGGCCATT TTTCCATCTC AATCCCTGTG AAGTCAGACA TTGCTCCTGT CGCTCGGTTG 
CTCATCTATG CTGTTTTACC TACCGGGGAC GTGATTGGGG ATTCTGCAAA ATATGATGTT 
GAAAATTGTC TGGCCAACAA GGTGGATTTG AGCTTCAGCC CATCACAAAG TCTCCCAGCC 
TCACACGCCC ACCTGCGAGT CACAGCGGCT CCTCAGTCCG TCTGCGCCCT CCGTGCTGTG 
GACCAAAGCG TGCTGCTCAT GAAGCCTGAT GCTGAGCTCT CGGCGTCCTC GGTTTACAAC 
CTGCTACCAG AAAAGGACCT CACTGGCTTC CCTGGGCCTT TGAATGACCA GGACAATGAA 
GACTGCATCA ATCGTCATAA TGTCTATATT AATGGAATCA CATATACTCC AGTATCAAGT 
ACAAATGAAA AGGATATGTA CAGCTTCCTA GAGGACATGG GCTTAAAGGC ATTCACCAAC 
TCAAAGATTC GTAAACCCAA AATGTGTCCA CAGCTTCAAC AGTATGAAAT GCATGGACCT 
GAAGGTCTAC GTGTAGGTTT TTATGAGTCA GATGTAATGG GAAGAGGCCA TGCACGCCTG 
GTGCATGTTG AAGAGCCTCA CACGGAGACC GTACGAAAGT ACTTCCCTGA GACATGGATC 
TGGGATTTGG TGGTGGTAAA CTCAGCAGGT GTGGCTGAGG TAGGAGTAAC AGTCCCTGAC 
ACCATCACCG AGTGGAAGGC AGGGGCCTTC TGCCTGTCTG AAGATGCTGG ACTTGGTATC 
TCTTCCACTG CCTCTCTCCG AGCCTTCCAG CCCTTCTTTG TGGAGCTCAC AATGCCTTAC 
TCTGTGATTC GTGGAGAGGC CTTCACACTC AAGGCCACGG TCCTAAACTA CCTTCCCAAA 
TGCATCCGGG TCAGTGTGCA GCTGGAAGCC TCTCCCGCCT TCCTAGCTGT CCCAGTGGAG 
AAGGAACAAG CGCCTCACTG CATCTGTGCA AACGGGCGGC AAACTGTGTC CTGGGCAGTA 
ACCCCAAAGT CATTAGGAAA TGTGAATTTC ACTGTGAGCG CAGAGGCACT AGAGTCTCAA 
GAGCTGTGTG GGACTGAGGT GCCTTCAGTT CCTGAACACG GAAGGAAAGA CACAGTCATC 
AAGCCTCTGT TGGTTGAACC TGAAGGACTA GAGAAGGAAA CAACATTCAA CTCCCTACTT 
TGTCCATCAG GTGGTGAGGT TTCTGAAGAA TTATCCCTGA AACTGCCACC AAATGTGGTA 
GAAGAATCTG CCCGAGCTTC TGTCTCAGTT TTGGGAGACA TATTAGGCTC TGCCATGCAA 
AACACACAAA ATCTTCTCCA GATGCCCTAT GGCTGTGGAG AGCAGAATAT GGTCCTCTTT 
GCTCCTAACA TCTATGTACT GGATTATCTA AATGAAACAC AGCAGCTTAC TCCAGAGATC 
AAGTCCAAGG CCATTGGCTA TCTCAACACT GGTTACCAGA GACAGTTGAA CTACAAACAC 
TATGATGGCT CCTACAGCAC CTTTGGGGAG CGATATGGCA GGAACCAGGG CAACACCTGG 
CTCACAGCCT TTGTTCTGAA GACTTTTGCC CAAGCTCGAG CCTACATCTT CATCGATGAA 
GCACACATTA CCCAAGCCCT CATATGGCTC TCCCAGAGGC AGAAGGACAA TGGCTGTTTC 
AGGAGCTCTG GGTCACTGCT CAACAATGCC ATAAAGGGAG GAGTAGAAGA TGAAGTGACC 
CTCTCCGCCT ATATCACCAT CGCCCTTCTG GAGATTCCTC TCACAGTCAC TCACCCTGTT 
GTCCGCAATG CCCTGTTTTG CCTGGAGTCA GCCTGGAAGA CAGCACAAGA AGGGGACCAT 
GGCAGCCATG TATATACCAA AGCACTGCTG GCCTATGCTT TTGCCCTGGC AGGTAACCAG 
GACAAGAGGA AGGAAGTACT CAAGTCACTT AATGAGGAAG CTGTGAAGAA AGACAACTCT 
GTCCATTGGG AGCGCCCTCA GAAACCCAAG GCACCAGTGG GGCATTTTTA CGAACCCCAG 
GCTCCCTCTG CTGAGGTGGA GATGACATCC TATGTGCTCC TCGCTTATCT CACGGCCCAG 
CCAGCCCCAA CCTCGGAGGA CCTGACCTCT GCAACCAACA TCGTGAAGTG GATCACGAAG 
CAGCAGAATG CCCAGGGCGG TTTCTCCTCC ACCCAGGACA CAGTGGTGGC TCTCCATGCT 
CTGTCCAAAT ATGGAGCAGC CACATTTACC AGGACTGGGA AGGCTGCACA GGTGACTATC 
CAGTCTTCAG GGACATTTTC CAGCAAATTC CAAGTGGACA ACAACAACCG CCTGTTACTG 
CAGCAGGTCT CATTGCCAGA GCTGCCTGGG GAATACAGCA TGAAAGTGAC AGGAGAAGGA 
TGTGTCTACC TCCAGACATC CTTGAAATAC AATATTCTCC CAGAAAAGGA AGAGTTCCCC 
TTTGCTTTAG GAGTGCAGAC TCTGCCTCAA ACTTGTGATG AACCCAAAGC CCACACCAGC 
TTCCAAATCT CCCTAAGTGT CAGTTACACA GGGAGCCGCT CTGCCTCCAA CATGGCGATC 
GTTGATGTGA AGATGGTCTC TGGCTTCATT CCCCTGAAGC CAACAGTGAA AATGCTTGAA 
AGATCTAACC ATGTGAGCCG GACAGAAGTC AGCAGCAACC ATGTCTTGAT TTACCTTGAT 
AAGGTGTCAA ATCAGACACT GAGCTTGTTC TTCACGGTTC TGCAAGATGT CCCAGTAAGA 
GATCTGAAAC CAGCCATAGT GAAAGTCTAT GATTACTACG AGACGGATGA GTTTGCAATT 
GCTGAGTACA ATGCTCCTTG CAGCAAAGGT AAGCCACTCA CACTCCTCCA AAAGGCAGTC 
AGAGCTCCTT CAGCTTGCCC CCCAAACCTT CTCCTTCATA AAACGCTGGG TAAATATTTG 
TCAAAAACAT CAAATTACTC ACACTGCACA TTATTATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	A2M
Entrez Gene ID	2
Full Name	alpha-2-macroglobulin
Synonyms	A2MD,CPAMD5,FWP007,S863-7
General protein information	Preferred Names alpha-2-macroglobulin Names alpha-2-macroglobulin C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5 alpha-2-M
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12p13.31
Summary	The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016].
Disorder MIM:	103950
Disorder Html:	Alpha-2-macroglobulin deficiency, 614036 (1); {Alzheimer disease, susceptibility to}, 104300 (3)

Rattus norvegicus (Norway rat)	LOC100911545	XP_003749876.1
Danio rerio (zebrafish)	LOC100003785	XP_005157599.1
Danio rerio (zebrafish)	a2ml	NP_001132951.1
Danio rerio (zebrafish)	LOC100006925	XP_001921577.3
Danio rerio (zebrafish)	LOC100006895	XP_001923676.1
Danio rerio (zebrafish)	LOC100006782	XP_001345438.5
Danio rerio (zebrafish)	a2ml1	XP_697477.6
Danio rerio (zebrafish)	zgc:171446	NP_001108028.1
Danio rerio (zebrafish)	sb:cb37	XP_001345541.5
Homo sapiens (human)	A2M	NP_000005.2
	A2M	XP_001114328.1
Canis lupus familiaris (dog)	A2M	XP_534893.3
Bos taurus (cattle)	A2M	NP_001103265.1
Danio rerio (zebrafish)	zgc:171426	XP_003198073.1
Danio rerio (zebrafish)	zgc:165453	XP_001918704.3
Pan troglodytes (chimpanzee)	A2M	XP_001139819.1
Danio rerio (zebrafish)	zgc:171445	NP_001107101.1
Mus musculus (house mouse)	A2m	NP_783327.2
Rattus norvegicus (Norway rat)	A2m	NP_036620.2
Gallus gallus (chicken)	A2M	XP_416476.3
Danio rerio (zebrafish)	zgc:165518	NP_001093623.2
Danio rerio (zebrafish)	si:dkey-52d15.2	XP_001345569.3
Danio rerio (zebrafish)	si:dkey-46g23.5	NP_001188334.1
Danio rerio (zebrafish)	si:dkey-46g23.2	XP_001332356.1
Xenopus tropicalis (tropical clawed frog)	LOC100489060	XP_002938549.2
Xenopus tropicalis (tropical clawed frog)	a2m	XP_002938550.2

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

A2M cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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