NLRP7 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NLRP7
Entrez Gene ID	199713
Full Name	NLR family pyrin domain containing 7
Synonyms	CLR19.4,HYDM,NALP7,NOD12,PAN7,PYPAF3
General protein information	Preferred Names NLR family pyrin domain containing 7 Names NACHT, LRR and PYD domains-containing protein 7 NACHT, LRR and PYD containing protein 7 NACHT, leucine rich repeat and PYD containing 7 PYRIN-containing Apaf1-like protein 3 nucleotide-binding oligomerization domain protein 12 nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 7
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.42
Summary	This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Disorder MIM:	609661
Disorder Html:	Hydatidiform mole, recurrent, 1, 231090 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_006723075.3	XP_006723138.1	NACHT, LRR and PYD domains-containing protein 7 isoform X2
NM_001127255.1	NP_001120727.1	NACHT, LRR and PYD domains-containing protein 7 isoform 3
NM_139176.3	NP_631915.2	NACHT, LRR and PYD domains-containing protein 7 isoform 1
XM_006723076.3	XP_006723139.1	NACHT, LRR and PYD domains-containing protein 7 isoform X2
XM_011526596.2	XP_011524898.1	NACHT, LRR and PYD domains-containing protein 7 isoform X1
XM_011526601.2	XP_011524903.1	NACHT, LRR and PYD domains-containing protein 7 isoform X3
XM_011526599.2	XP_011524901.1	NACHT, LRR and PYD domains-containing protein 7 isoform X2
NM_206828.3	NP_996611.2	NACHT, LRR and PYD domains-containing protein 7 isoform 2

Pathways from BioSystems

Homologies

	NLRP7	NP_001107825.1
Pan troglodytes (chimpanzee)	NLRP7	XP_512902.3
Homo sapiens (human)	NLRP7	NP_001120727.1

Gene Ontology
Bibliography

Related articles in PubMed

Exome sequencing and genotyping identify a rare variant in NLRP7 gene associated with ulcerative colitis.
Onoufriadis A, Stone K, Katsiamides A, Amar A, Omar Y, de Lange K, Taylor K, Barrett JC, Pollok R, Hayee B, Mansfield JC, Sanderson JD, Simpson MA, Mathew CG, Prescott NJ
Journal of Crohn's & colitis(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Maternal heterozygous nonsense deletion in NLRP7 leads to recurrent reproductive failure and DNA methylation disturbances in the offspring.
Title: Maternal heterozygous NLRP7 variant results in recurrent reproductive failure and imprinting disturbances in the offspring.

Eleven novel protein-truncating variants in NLRP7 identified in hydatidiform mole patients. Most of the breakpoints occurred within Alu repeats.
Title: The genomic architecture of NLRP7 is Alu rich and predisposes to disease-associated large deletions.

data underscore the involvement of NLR family pyrin domain containing 7 (NLRP7) in recurrent hydatidiform mole pathophysiology and confirm that DNA methylation of specific regions is critical
Title: Novel Nonsense Mutation in the NLRP7 Gene Associated with Recurrent Hydatidiform Mole.

the NLRP7 inflammasome contributes to IL-1beta secretion and induction of pyroptosis in response to M. bovis infection in THP-1 macrophages.
Title: Virulent Mycobacterium bovis Beijing Strain Activates the NLRP7 Inflammasome in THP-1 Macrophages.

maternal-effect mutations of NLRP7 are associated with the most severe form of multi-locus imprinting defects in humans
Title: Absence of Maternal Methylation in Biparental Hydatidiform Moles from Women with NLRP7 Maternal-Effect Mutations Reveals Widespread Placenta-Specific Imprinting.

The following NLRP7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NLRP7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu14172	NM_206828.3 Latest version!	Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu14030	NM_139176.3 Latest version!	Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
OHu18156	NM_001127255.1 Latest version!	Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
OHu18156	XM_011526599.2 Latest version!	Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
OHu18156	XM_006723075.3 Latest version!	Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
OHu18156	XM_006723076.3 Latest version!	Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
OHu77568	XM_011526596.2 Latest version!	Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
OHu77569	XM_011526601.2 Latest version!	Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NLRP7 ( NM_206828.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_996611.2 Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu14172
Clone ID Related Accession (Same CDS sequence)	NM_206828.3
Accession Version	NM_206828.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2943bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 7 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC425389.1, AF464765.1 and AY154462.1. On May 11, 2008 this sequence version replaced NM_206828.2. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 3, resulting in a shorter protein (isoform 2), compared to isoform 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY154462.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142363 [ECO:0000348] ##Evidence-Data-END##

ATGACATCGC CCCAGCTAGA GTGGACTCTG CAGACCCTTC TGGAGCAGCT GAACGAGGAT 
GAATTAAAGA GTTTCAAATC CCTTTTATGG GCTTTTCCCC TCGAAGACGT GCTACAGAAG 
ACCCCATGGT CTGAGGTGGA AGAGGCTGAT GGCAAGAAAC TGGCAGAAAT TCTGGTCAAC 
ACCTCCTCAG AAAATTGGAT AAGGAATGCG ACTGTGAACA TCTTGGAAGA GATGAATCTC 
ACGGAATTGT GTAAGATGGC AAAGGCTGAG ATGATGGAGG ACGGACAGGT GCAAGAAATA 
GATAATCCTG AGCTGGGAGA TGCAGAAGAA GACTCGGAGT TAGCAAAGCC AGGTGAAAAG 
GAAGGATGGA GAAATTCAAT GGAGAAACAG TCTTTGGTCT GGAAGAACAC CTTTTGGCAA 
GGAGACATTG ACAATTTCCA TGACGACGTC ACTCTGAGAA ACCAACGGTT CATTCCATTC 
TTGAATCCCA GAACACCCAG GAAGCTAACA CCTTACACGG TGGTGCTGCA CGGCCCCGCA 
GGCGTGGGGA AAACCACGCT GGCCAAAAAG TGTATGCTGG ACTGGACAGA CTGCAACCTC 
AGCCCGACGC TCAGATACGC GTTCTACCTC AGCTGCAAGG AGCTCAGCCG CATGGGCCCC 
TGCAGTTTTG CAGAGCTGAT CTCCAAAGAC TGGCCTGAAT TGCAGGATGA CATTCCAAGC 
ATCCTAGCCC AAGCACAGAG AATCCTGTTC GTGGTCGATG GCCTTGATGA GCTGAAAGTC 
CCACCTGGGG CGCTGATCCA GGACATCTGC GGGGACTGGG AGAAGAAGAA GCCGGTGCCC 
GTCCTCCTGG GGAGTTTGCT GAAGAGGAAG ATGTTACCCA GGGCAGCCTT GCTGGTCACC 
ACGCGGCCCA GGGCACTGAG GGACCTCCAG CTCCTGGCGC AGCAGCCGAT CTACGTAAGG 
GTGGAGGGCT TCCTGGAGGA GGACAGGAGG GCCTATTTCC TGAGACACTT TGGAGACGAG 
GACCAAGCCA TGCGTGCCTT TGAGCTAATG AGGAGCAACG CGGCCCTGTT CCAGCTGGGC 
TCGGCCCCCG CGGTGTGCTG GATTGTGTGC ACGACTCTGA AGCTGCAGAT GGAGAAGGGG 
GAGGACCCGG TCCCCACCTG CCTCACCCGC ACGGGGCTGT TCCTGCGTTT CCTCTGCAGC 
CGGTTCCCGC AGGGCGCACA GCTGCGGGGC GCGCTGCGGA CGCTGAGCCT CCTGGCCGCG 
CAGGGCCTGT GGGCGCAGAT GTCCGTGTTC CACCGAGAGG ACCTGGAAAG GCTCGGGGTG 
CAGGAGTCCG ACCTCCGTCT GTTCCTGGAC GGAGACATCC TCCGCCAGGA CAGAGTCTCC 
AAAGGCTGCT ACTCCTTCAT CCACCTCAGC TTCCAGCAGT TTCTCACTGC CCTGTTCTAC 
GCCCTGGAGA AGGAGGAGGG GGAGGACAGG GACGGCCACG CCTGGGACAT CGGGGACGTA 
CAGAAGCTGC TTTCCGGAGA AGAAAGACTC AAGAACCCCG ACCTGATTCA AGTAGGACAC 
TTCTTATTCG GCCTCGCTAA CGAGAAGAGA GCCAAGGAGT TGGAGGCCAC TTTTGGCTGC 
CGGATGTCAC CGGACATCAA ACAGGAATTG CTGCAATGCA AAGCACATCT TCATGCAAAT 
AAGCCCTTAT CCGTGACCGA CCTGAAGGAG GTCTTGGGCT GCCTGTATGA GTCTCAGGAG 
GAGGAGCTGG CGAAGGTGGT GGTGGCCCCG TTCAAGGAAA TTTCTATTCA CCTGACAAAT 
ACTTCTGAAG TGATGCATTG TTCCTTCAGC CTGAAGCATT GTCAAGACTT GCAGAAACTC 
TCACTGCAGG TAGCAAAGGG GGTGTTCCTG GAGAATTACA TGGATTTTGA ACTGGACATT 
GAATTTGAAA GGTGCACTTA CCTAACCATT CCGAACTGGG CTCGGCAGGA TCTTCGCTCT 
CTTCGCCTCT GGACAGATTT CTGCTCTCTC TTCAGCTCAA ACAGCAACCT CAAGTTTCTG 
GAAGTGAAAC AAAGCTTCCT GAGTGACTCT TCTGTGCGGA TTCTTTGTGA CCACGTAACC 
CGTAGCACCT GTCATCTGCA GAAAGTGGAG ATTAAAAACG TCACCCCTGA CACCGCGTAC 
CGGGACTTCT GTCTTGCTTT CATTGGGAAG AAGACCCTCA CGCACCTGAC CCTGGCAGGG 
CACATCGAGT GGGAACGCAC GATGATGCTG ATGCTGTGTG ACCTGCTCAG AAATCATAAA 
TGCAACCTGC AGTACCTGAG GTTGGGAGGT CACTGTGCCA CCCCGGAGCA GTGGGCTGAA 
TTCTTCTATG TCCTCAAAGC CAACCAGTCC CTGAAGCACC TGCGTCTCTC AGCCAATGTG 
CTCCTGGATG AGGGTGCCAT GTTGCTGTAC AAGACCATGA CACGCCCAAA ACACTTCCTG 
CAGATGTTGT CGTTGGAAAA CTGTCGTCTT ACAGAAGCCA GTTGCAAGGA CCTTGCTGCT 
GTCTTGGTTG TCAGCAAGAA GCTGACACAC CTGTGCTTGG CCAAGAACCC CATTGGGGAT 
ACAGGGGTGA AGTTTCTGTG TGAGGGCTTG AGTTACCCTG ATTGTAAACT GCAGACCTTG 
GTGTTACAGC AATGCAGCAT AACCAAGCTT GGCTGTAGAT ATCTCTCAGA GGCGCTCCAA 
GAAGCCTGCA GCCTCACAAA CCTGGACTTG AGTATCAACC AGATAGCTCG TGGATTGTGG 
ATTCTCTGTC AGGCATTAGA GAATCCAAAC TGTAACCTAA AACACCTACG GTTGAAGACC 
TATGAAACTA ATTTGGAAAT CAAGAAGCTG TTGGAGGAAG TGAAAGAAAA GAATCCCAAG 
CTGACTATTG ATTGCAATGC TTCCGGGGCA ACGGCACCTC CGTGCTGTGA CTTTTTTTGC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_996611.2
CDS	77..3019
Translation	MTSPQLEWTLQTLLEQLNEDELKSFKSLLWAFPLEDVLQKTPWSEVEEADGKKLAEILVNTSSENWIRNATVNILEEMNLTELCKMAKAEMMEDGQVQEIDNPELGDAEEDSELAKPGEKEGWRNSMEKQSLVWKNTFWQGDIDNFHDDVTLRNQRFIPFLNPRTPRKLTPYTVVLHGPAGVGKTTLAKKCMLDWTDCNLSPTLRYAFYLSCKELSRMGPCSFAELISKDWPELQDDIPSILAQAQRILFVVDGLDELKVPPGALIQDICGDWEKKKPVPVLLGSLLKRKMLPRAALLVTTRPRALRDLQLLAQQPIYVRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQGAQLRGALRTLSLLAAQGLWAQMSVFHREDLERLGVQESDLRLFLDGDILRQDRVSKGCYSFIHLSFQQFLTALFYALEKEEGEDRDGHAWDIGDVQKLLSGEERLKNPDLIQVGHFLFGLANEKRAKELEATFGCRMSPDIKQELLQCKAHLHANKPLSVTDLKEVLGCLYESQEEELAKVVVAPFKEISIHLTNTSEVMHCSFSLKHCQDLQKLSLQVAKGVFLENYMDFELDIEFERCTYLTIPNWARQDLRSLRLWTDFCSLFSSNSNLKFLEVKQSFLSDSSVRILCDHVTRSTCHLQKVEIKNVTPDTAYRDFCLAFIGKKTLTHLTLAGHIEWERTMMLMLCDLLRNHKCNLQYLRLGGHCATPEQWAEFFYVLKANQSLKHLRLSANVLLDEGAMLLYKTMTRPKHFLQMLSLENCRLTEASCKDLAAVLVVSKKLTHLCLAKNPIGDTGVKFLCEGLSYPDCKLQTLVLQQCSITKLGCRYLSEALQEACSLTNLDLSINQIARGLWILCQALENPNCNLKHLRLKTYETNLEIKKLLEEVKEKNPKLTIDCNASGATAPPCCDFFC

Target ORF information:

RefSeq Version	NM_206828.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_206828.3

ORF Insert Sequence:

ATGACATCGC CCCAGCTAGA GTGGACTCTG CAGACCCTTC TGGAGCAGCT GAACGAGGAT 
GAATTAAAGA GTTTCAAATC CCTTTTATGG GCTTTTCCCC TCGAAGACGT GCTACAGAAG 
ACCCCATGGT CTGAGGTGGA AGAGGCTGAT GGCAAGAAAC TGGCAGAAAT TCTGGTCAAC 
ACCTCCTCAG AAAATTGGAT AAGGAATGCG ACTGTGAACA TCTTGGAAGA GATGAATCTC 
ACGGAATTGT GTAAGATGGC AAAGGCTGAG ATGATGGAGG ACGGACAGGT GCAAGAAATA 
GATAATCCTG AGCTGGGAGA TGCAGAAGAA GACTCGGAGT TAGCAAAGCC AGGTGAAAAG 
GAAGGATGGA GAAATTCAAT GGAGAAACAG TCTTTGGTCT GGAAGAACAC CTTTTGGCAA 
GGAGACATTG ACAATTTCCA TGACGACGTC ACTCTGAGAA ACCAACGGTT CATTCCATTC 
TTGAATCCCA GAACACCCAG GAAGCTAACA CCTTACACGG TGGTGCTGCA CGGCCCCGCA 
GGCGTGGGGA AAACCACGCT GGCCAAAAAG TGTATGCTGG ACTGGACAGA CTGCAACCTC 
AGCCCGACGC TCAGATACGC GTTCTACCTC AGCTGCAAGG AGCTCAGCCG CATGGGCCCC 
TGCAGTTTTG CAGAGCTGAT CTCCAAAGAC TGGCCTGAAT TGCAGGATGA CATTCCAAGC 
ATCCTAGCCC AAGCACAGAG AATCCTGTTC GTGGTCGATG GCCTTGATGA GCTGAAAGTC 
CCACCTGGGG CGCTGATCCA GGACATCTGC GGGGACTGGG AGAAGAAGAA GCCGGTGCCC 
GTCCTCCTGG GGAGTTTGCT GAAGAGGAAG ATGTTACCCA GGGCAGCCTT GCTGGTCACC 
ACGCGGCCCA GGGCACTGAG GGACCTCCAG CTCCTGGCGC AGCAGCCGAT CTACGTAAGG 
GTGGAGGGCT TCCTGGAGGA GGACAGGAGG GCCTATTTCC TGAGACACTT TGGAGACGAG 
GACCAAGCCA TGCGTGCCTT TGAGCTAATG AGGAGCAACG CGGCCCTGTT CCAGCTGGGC 
TCGGCCCCCG CGGTGTGCTG GATTGTGTGC ACGACTCTGA AGCTGCAGAT GGAGAAGGGG 
GAGGACCCGG TCCCCACCTG CCTCACCCGC ACGGGGCTGT TCCTGCGTTT CCTCTGCAGC 
CGGTTCCCGC AGGGCGCACA GCTGCGGGGC GCGCTGCGGA CGCTGAGCCT CCTGGCCGCG 
CAGGGCCTGT GGGCGCAGAT GTCCGTGTTC CACCGAGAGG ACCTGGAAAG GCTCGGGGTG 
CAGGAGTCCG ACCTCCGTCT GTTCCTGGAC GGAGACATCC TCCGCCAGGA CAGAGTCTCC 
AAAGGCTGCT ACTCCTTCAT CCACCTCAGC TTCCAGCAGT TTCTCACTGC CCTGTTCTAC 
GCCCTGGAGA AGGAGGAGGG GGAGGACAGG GACGGCCACG CCTGGGACAT CGGGGACGTA 
CAGAAGCTGC TTTCCGGAGA AGAAAGACTC AAGAACCCCG ACCTGATTCA AGTAGGACAC 
TTCTTATTCG GCCTCGCTAA CGAGAAGAGA GCCAAGGAGT TGGAGGCCAC TTTTGGCTGC 
CGGATGTCAC CGGACATCAA ACAGGAATTG CTGCAATGCA AAGCACATCT TCATGCAAAT 
AAGCCCTTAT CCGTGACCGA CCTGAAGGAG GTCTTGGGCT GCCTGTATGA GTCTCAGGAG 
GAGGAGCTGG CGAAGGTGGT GGTGGCCCCG TTCAAGGAAA TTTCTATTCA CCTGACAAAT 
ACTTCTGAAG TGATGCATTG TTCCTTCAGC CTGAAGCATT GTCAAGACTT GCAGAAACTC 
TCACTGCAGG TAGCAAAGGG GGTGTTCCTG GAGAATTACA TGGATTTTGA ACTGGACATT 
GAATTTGAAA GGTGCACTTA CCTAACCATT CCGAACTGGG CTCGGCAGGA TCTTCGCTCT 
CTTCGCCTCT GGACAGATTT CTGCTCTCTC TTCAGCTCAA ACAGCAACCT CAAGTTTCTG 
GAAGTGAAAC AAAGCTTCCT GAGTGACTCT TCTGTGCGGA TTCTTTGTGA CCACGTAACC 
CGTAGCACCT GTCATCTGCA GAAAGTGGAG ATTAAAAACG TCACCCCTGA CACCGCGTAC 
CGGGACTTCT GTCTTGCTTT CATTGGGAAG AAGACCCTCA CGCACCTGAC CCTGGCAGGG 
CACATCGAGT GGGAACGCAC GATGATGCTG ATGCTGTGTG ACCTGCTCAG AAATCATAAA 
TGCAACCTGC AGTACCTGAG GTTGGGAGGT CACTGTGCCA CCCCGGAGCA GTGGGCTGAA 
TTCTTCTATG TCCTCAAAGC CAACCAGTCC CTGAAGCACC TGCGTCTCTC AGCCAATGTG 
CTCCTGGATG AGGGTGCCAT GTTGCTGTAC AAGACCATGA CACGCCCAAA ACACTTCCTG 
CAGATGTTGT CGTTGGAAAA CTGTCGTCTT ACAGAAGCCA GTTGCAAGGA CCTTGCTGCT 
GTCTTGGTTG TCAGCAAGAA GCTGACACAC CTGTGCTTGG CCAAGAACCC CATTGGGGAT 
ACAGGGGTGA AGTTTCTGTG TGAGGGCTTG AGTTACCCTG ATTGTAAACT GCAGACCTTG 
GTGTTACAGC AATGCAGCAT AACCAAGCTT GGCTGTAGAT ATCTCTCAGA GGCGCTCCAA 
GAAGCCTGCA GCCTCACAAA CCTGGACTTG AGTATCAACC AGATAGCTCG TGGATTGTGG 
ATTCTCTGTC AGGCATTAGA GAATCCAAAC TGTAACCTAA AACACCTACG GTTGAAGACC 
TATGAAACTA ATTTGGAAAT CAAGAAGCTG TTGGAGGAAG TGAAAGAAAA GAATCCCAAG 
CTGACTATTG ATTGCAATGC TTCCGGGGCA ACGGCACCTC CGTGCTGTGA CTTTTTTTGC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP7 ( NM_139176.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_631915.2 Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu14030
Clone ID Related Accession (Same CDS sequence)	NM_139176.3
Accession Version	NM_139176.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3030bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 7 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC425389.1, BK001113.1 and AF464765.1. On May 11, 2008 this sequence version replaced NM_139176.2. Transcript Variant: This variant (1) uses an alternate in-frame splice site in the 5' coding region, compared to variant 3, resulting in a shorter protein (isoform 1), compared to isoform 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BK001113.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGACATCGC CCCAGCTAGA GTGGACTCTG CAGACCCTTC TGGAGCAGCT GAACGAGGAT 
GAATTAAAGA GTTTCAAATC CCTTTTATGG GCTTTTCCCC TCGAAGACGT GCTACAGAAG 
ACCCCATGGT CTGAGGTGGA AGAGGCTGAT GGCAAGAAAC TGGCAGAAAT TCTGGTCAAC 
ACCTCCTCAG AAAATTGGAT AAGGAATGCG ACTGTGAACA TCTTGGAAGA GATGAATCTC 
ACGGAATTGT GTAAGATGGC AAAGGCTGAG ATGATGGAGG ACGGACAGGT GCAAGAAATA 
GATAATCCTG AGCTGGGAGA TGCAGAAGAA GACTCGGAGT TAGCAAAGCC AGGTGAAAAG 
GAAGGATGGA GAAATTCAAT GGAGAAACAG TCTTTGGTCT GGAAGAACAC CTTTTGGCAA 
GGAGACATTG ACAATTTCCA TGACGACGTC ACTCTGAGAA ACCAACGGTT CATTCCATTC 
TTGAATCCCA GAACACCCAG GAAGCTAACA CCTTACACGG TGGTGCTGCA CGGCCCCGCA 
GGCGTGGGGA AAACCACGCT GGCCAAAAAG TGTATGCTGG ACTGGACAGA CTGCAACCTC 
AGCCCGACGC TCAGATACGC GTTCTACCTC AGCTGCAAGG AGCTCAGCCG CATGGGCCCC 
TGCAGTTTTG CAGAGCTGAT CTCCAAAGAC TGGCCTGAAT TGCAGGATGA CATTCCAAGC 
ATCCTAGCCC AAGCACAGAG AATCCTGTTC GTGGTCGATG GCCTTGATGA GCTGAAAGTC 
CCACCTGGGG CGCTGATCCA GGACATCTGC GGGGACTGGG AGAAGAAGAA GCCGGTGCCC 
GTCCTCCTGG GGAGTTTGCT GAAGAGGAAG ATGTTACCCA GGGCAGCCTT GCTGGTCACC 
ACGCGGCCCA GGGCACTGAG GGACCTCCAG CTCCTGGCGC AGCAGCCGAT CTACGTAAGG 
GTGGAGGGCT TCCTGGAGGA GGACAGGAGG GCCTATTTCC TGAGACACTT TGGAGACGAG 
GACCAAGCCA TGCGTGCCTT TGAGCTAATG AGGAGCAACG CGGCCCTGTT CCAGCTGGGC 
TCGGCCCCCG CGGTGTGCTG GATTGTGTGC ACGACTCTGA AGCTGCAGAT GGAGAAGGGG 
GAGGACCCGG TCCCCACCTG CCTCACCCGC ACGGGGCTGT TCCTGCGTTT CCTCTGCAGC 
CGGTTCCCGC AGGGCGCACA GCTGCGGGGC GCGCTGCGGA CGCTGAGCCT CCTGGCCGCG 
CAGGGCCTGT GGGCGCAGAT GTCCGTGTTC CACCGAGAGG ACCTGGAAAG GCTCGGGGTG 
CAGGAGTCCG ACCTCCGTCT GTTCCTGGAC GGAGACATCC TCCGCCAGGA CAGAGTCTCC 
AAAGGCTGCT ACTCCTTCAT CCACCTCAGC TTCCAGCAGT TTCTCACTGC CCTGTTCTAC 
GCCCTGGAGA AGGAGGAGGG GGAGGACAGG GACGGCCACG CCTGGGACAT CGGGGACGTA 
CAGAAGCTGC TTTCCGGAGA AGAAAGACTC AAGAACCCCG ACCTGATTCA AGTAGGACAC 
TTCTTATTCG GCCTCGCTAA CGAGAAGAGA GCCAAGGAGT TGGAGGCCAC TTTTGGCTGC 
CGGATGTCAC CGGACATCAA ACAGGAATTG CTGCAATGCA AAGCACATCT TCATGCAAAT 
AAGCCCTTAT CCGTGACCGA CCTGAAGGAG GTCTTGGGCT GCCTGTATGA GTCTCAGGAG 
GAGGAGCTGG CGAAGGTGGT GGTGGCCCCG TTCAAGGAAA TTTCTATTCA CCTGACAAAT 
ACTTCTGAAG TGATGCATTG TTCCTTCAGC CTGAAGCATT GTCAAGACTT GCAGAAACTC 
TCACTGCAGG TAGCAAAGGG GGTGTTCCTG GAGAATTACA TGGATTTTGA ACTGGACATT 
GAATTTGAAA GCTCAAACAG CAACCTCAAG TTTCTGGAAG TGAAACAAAG CTTCCTGAGT 
GACTCTTCTG TGCGGATTCT TTGTGACCAC GTAACCCGTA GCACCTGTCA TCTGCAGAAA 
GTGGAGATTA AAAACGTCAC CCCTGACACC GCGTACCGGG ACTTCTGTCT TGCTTTCATT 
GGGAAGAAGA CCCTCACGCA CCTGACCCTG GCAGGGCACA TCGAGTGGGA ACGCACGATG 
ATGCTGATGC TGTGTGACCT GCTCAGAAAT CATAAATGCA ACCTGCAGTA CCTGAGGTTG 
GGAGGTCACT GTGCCACCCC GGAGCAGTGG GCTGAATTCT TCTATGTCCT CAAAGCCAAC 
CAGTCCCTGA AGCACCTGCG TCTCTCAGCC AATGTGCTCC TGGATGAGGG TGCCATGTTG 
CTGTACAAGA CCATGACACG CCCAAAACAC TTCCTGCAGA TGTTGTCGTT GGAAAACTGT 
CGTCTTACAG AAGCCAGTTG CAAGGACCTT GCTGCTGTCT TGGTTGTCAG CAAGAAGCTG 
ACACACCTGT GCTTGGCCAA GAACCCCATT GGGGATACAG GGGTGAAGTT TCTGTGTGAG 
GGCTTGAGTT ACCCTGATTG TAAACTGCAG ACCTTGGTGT TACAGCAATG CAGCATAACC 
AAGCTTGGCT GTAGATATCT CTCAGAGGCG CTCCAAGAAG CCTGCAGCCT CACAAACCTG 
GACTTGAGTA TCAACCAGAT AGCTCGTGGA TTGTGGATTC TCTGTCAGGC ATTAGAGAAT 
CCAAACTGTA ACCTAAAACA CCTACGCCTC TGGAGCTGCT CCCTCATGCC TTTCTATTGT 
CAGCATCTTG GATCTGCTCT CCTCAGCAAT CAGAAGCTTG AAACTCTGGA CCTGGGCCAG 
AATCATTTGT GGAAGAGTGG CATAATTAAG CTCTTTGGGG TTCTAAGACA AAGAACTGGA 
TCCTTGAAGA TACTCAGGTT GAAGACCTAT GAAACTAATT TGGAAATCAA GAAGCTGTTG 
GAGGAAGTGA AAGAAAAGAA TCCCAAGCTG ACTATTGATT GCAATGCTTC CGGGGCAACG 
GCACCTCCGT GCTGTGACTT TTTTTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_631915.2
CDS	77..3106
Translation	MTSPQLEWTLQTLLEQLNEDELKSFKSLLWAFPLEDVLQKTPWSEVEEADGKKLAEILVNTSSENWIRNATVNILEEMNLTELCKMAKAEMMEDGQVQEIDNPELGDAEEDSELAKPGEKEGWRNSMEKQSLVWKNTFWQGDIDNFHDDVTLRNQRFIPFLNPRTPRKLTPYTVVLHGPAGVGKTTLAKKCMLDWTDCNLSPTLRYAFYLSCKELSRMGPCSFAELISKDWPELQDDIPSILAQAQRILFVVDGLDELKVPPGALIQDICGDWEKKKPVPVLLGSLLKRKMLPRAALLVTTRPRALRDLQLLAQQPIYVRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQGAQLRGALRTLSLLAAQGLWAQMSVFHREDLERLGVQESDLRLFLDGDILRQDRVSKGCYSFIHLSFQQFLTALFYALEKEEGEDRDGHAWDIGDVQKLLSGEERLKNPDLIQVGHFLFGLANEKRAKELEATFGCRMSPDIKQELLQCKAHLHANKPLSVTDLKEVLGCLYESQEEELAKVVVAPFKEISIHLTNTSEVMHCSFSLKHCQDLQKLSLQVAKGVFLENYMDFELDIEFESSNSNLKFLEVKQSFLSDSSVRILCDHVTRSTCHLQKVEIKNVTPDTAYRDFCLAFIGKKTLTHLTLAGHIEWERTMMLMLCDLLRNHKCNLQYLRLGGHCATPEQWAEFFYVLKANQSLKHLRLSANVLLDEGAMLLYKTMTRPKHFLQMLSLENCRLTEASCKDLAAVLVVSKKLTHLCLAKNPIGDTGVKFLCEGLSYPDCKLQTLVLQQCSITKLGCRYLSEALQEACSLTNLDLSINQIARGLWILCQALENPNCNLKHLRLWSCSLMPFYCQHLGSALLSNQKLETLDLGQNHLWKSGIIKLFGVLRQRTGSLKILRLKTYETNLEIKKLLEEVKEKNPKLTIDCNASGATAPPCCDFFC

Target ORF information:

RefSeq Version	NM_139176.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139176.3

ORF Insert Sequence:

ATGACATCGC CCCAGCTAGA GTGGACTCTG CAGACCCTTC TGGAGCAGCT GAACGAGGAT 
GAATTAAAGA GTTTCAAATC CCTTTTATGG GCTTTTCCCC TCGAAGACGT GCTACAGAAG 
ACCCCATGGT CTGAGGTGGA AGAGGCTGAT GGCAAGAAAC TGGCAGAAAT TCTGGTCAAC 
ACCTCCTCAG AAAATTGGAT AAGGAATGCG ACTGTGAACA TCTTGGAAGA GATGAATCTC 
ACGGAATTGT GTAAGATGGC AAAGGCTGAG ATGATGGAGG ACGGACAGGT GCAAGAAATA 
GATAATCCTG AGCTGGGAGA TGCAGAAGAA GACTCGGAGT TAGCAAAGCC AGGTGAAAAG 
GAAGGATGGA GAAATTCAAT GGAGAAACAG TCTTTGGTCT GGAAGAACAC CTTTTGGCAA 
GGAGACATTG ACAATTTCCA TGACGACGTC ACTCTGAGAA ACCAACGGTT CATTCCATTC 
TTGAATCCCA GAACACCCAG GAAGCTAACA CCTTACACGG TGGTGCTGCA CGGCCCCGCA 
GGCGTGGGGA AAACCACGCT GGCCAAAAAG TGTATGCTGG ACTGGACAGA CTGCAACCTC 
AGCCCGACGC TCAGATACGC GTTCTACCTC AGCTGCAAGG AGCTCAGCCG CATGGGCCCC 
TGCAGTTTTG CAGAGCTGAT CTCCAAAGAC TGGCCTGAAT TGCAGGATGA CATTCCAAGC 
ATCCTAGCCC AAGCACAGAG AATCCTGTTC GTGGTCGATG GCCTTGATGA GCTGAAAGTC 
CCACCTGGGG CGCTGATCCA GGACATCTGC GGGGACTGGG AGAAGAAGAA GCCGGTGCCC 
GTCCTCCTGG GGAGTTTGCT GAAGAGGAAG ATGTTACCCA GGGCAGCCTT GCTGGTCACC 
ACGCGGCCCA GGGCACTGAG GGACCTCCAG CTCCTGGCGC AGCAGCCGAT CTACGTAAGG 
GTGGAGGGCT TCCTGGAGGA GGACAGGAGG GCCTATTTCC TGAGACACTT TGGAGACGAG 
GACCAAGCCA TGCGTGCCTT TGAGCTAATG AGGAGCAACG CGGCCCTGTT CCAGCTGGGC 
TCGGCCCCCG CGGTGTGCTG GATTGTGTGC ACGACTCTGA AGCTGCAGAT GGAGAAGGGG 
GAGGACCCGG TCCCCACCTG CCTCACCCGC ACGGGGCTGT TCCTGCGTTT CCTCTGCAGC 
CGGTTCCCGC AGGGCGCACA GCTGCGGGGC GCGCTGCGGA CGCTGAGCCT CCTGGCCGCG 
CAGGGCCTGT GGGCGCAGAT GTCCGTGTTC CACCGAGAGG ACCTGGAAAG GCTCGGGGTG 
CAGGAGTCCG ACCTCCGTCT GTTCCTGGAC GGAGACATCC TCCGCCAGGA CAGAGTCTCC 
AAAGGCTGCT ACTCCTTCAT CCACCTCAGC TTCCAGCAGT TTCTCACTGC CCTGTTCTAC 
GCCCTGGAGA AGGAGGAGGG GGAGGACAGG GACGGCCACG CCTGGGACAT CGGGGACGTA 
CAGAAGCTGC TTTCCGGAGA AGAAAGACTC AAGAACCCCG ACCTGATTCA AGTAGGACAC 
TTCTTATTCG GCCTCGCTAA CGAGAAGAGA GCCAAGGAGT TGGAGGCCAC TTTTGGCTGC 
CGGATGTCAC CGGACATCAA ACAGGAATTG CTGCAATGCA AAGCACATCT TCATGCAAAT 
AAGCCCTTAT CCGTGACCGA CCTGAAGGAG GTCTTGGGCT GCCTGTATGA GTCTCAGGAG 
GAGGAGCTGG CGAAGGTGGT GGTGGCCCCG TTCAAGGAAA TTTCTATTCA CCTGACAAAT 
ACTTCTGAAG TGATGCATTG TTCCTTCAGC CTGAAGCATT GTCAAGACTT GCAGAAACTC 
TCACTGCAGG TAGCAAAGGG GGTGTTCCTG GAGAATTACA TGGATTTTGA ACTGGACATT 
GAATTTGAAA GCTCAAACAG CAACCTCAAG TTTCTGGAAG TGAAACAAAG CTTCCTGAGT 
GACTCTTCTG TGCGGATTCT TTGTGACCAC GTAACCCGTA GCACCTGTCA TCTGCAGAAA 
GTGGAGATTA AAAACGTCAC CCCTGACACC GCGTACCGGG ACTTCTGTCT TGCTTTCATT 
GGGAAGAAGA CCCTCACGCA CCTGACCCTG GCAGGGCACA TCGAGTGGGA ACGCACGATG 
ATGCTGATGC TGTGTGACCT GCTCAGAAAT CATAAATGCA ACCTGCAGTA CCTGAGGTTG 
GGAGGTCACT GTGCCACCCC GGAGCAGTGG GCTGAATTCT TCTATGTCCT CAAAGCCAAC 
CAGTCCCTGA AGCACCTGCG TCTCTCAGCC AATGTGCTCC TGGATGAGGG TGCCATGTTG 
CTGTACAAGA CCATGACACG CCCAAAACAC TTCCTGCAGA TGTTGTCGTT GGAAAACTGT 
CGTCTTACAG AAGCCAGTTG CAAGGACCTT GCTGCTGTCT TGGTTGTCAG CAAGAAGCTG 
ACACACCTGT GCTTGGCCAA GAACCCCATT GGGGATACAG GGGTGAAGTT TCTGTGTGAG 
GGCTTGAGTT ACCCTGATTG TAAACTGCAG ACCTTGGTGT TACAGCAATG CAGCATAACC 
AAGCTTGGCT GTAGATATCT CTCAGAGGCG CTCCAAGAAG CCTGCAGCCT CACAAACCTG 
GACTTGAGTA TCAACCAGAT AGCTCGTGGA TTGTGGATTC TCTGTCAGGC ATTAGAGAAT 
CCAAACTGTA ACCTAAAACA CCTACGCCTC TGGAGCTGCT CCCTCATGCC TTTCTATTGT 
CAGCATCTTG GATCTGCTCT CCTCAGCAAT CAGAAGCTTG AAACTCTGGA CCTGGGCCAG 
AATCATTTGT GGAAGAGTGG CATAATTAAG CTCTTTGGGG TTCTAAGACA AAGAACTGGA 
TCCTTGAAGA TACTCAGGTT GAAGACCTAT GAAACTAATT TGGAAATCAA GAAGCTGTTG 
GAGGAAGTGA AAGAAAAGAA TCCCAAGCTG ACTATTGATT GCAATGCTTC CGGGGCAACG 
GCACCTCCGT GCTGTGACTT TTTTTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP7 ( NM_001127255.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001120727.1 Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant 3, mRNA.

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CloneID	OHu18156
Clone ID Related Accession (Same CDS sequence)	XM_006723075.3 , NM_001127255.1 , XM_006723076.3 , XM_011526599.2
Accession Version	NM_001127255.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3114bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 7 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC425389.1, AY154462.1, AF464765.1 and BC109125.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC109125.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142363 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END##

ATGACATCGC CCCAGCTAGA GTGGACTCTG CAGACCCTTC TGGAGCAGCT GAACGAGGAT 
GAATTAAAGA GTTTCAAATC CCTTTTATGG GCTTTTCCCC TCGAAGACGT GCTACAGAAG 
ACCCCATGGT CTGAGGTGGA AGAGGCTGAT GGCAAGAAAC TGGCAGAAAT TCTGGTCAAC 
ACCTCCTCAG AAAATTGGAT AAGGAATGCG ACTGTGAACA TCTTGGAAGA GATGAATCTC 
ACGGAATTGT GTAAGATGGC AAAGGCTGAG ATGATGGAGG ACGGACAGGT GCAAGAAATA 
GATAATCCTG AGCTGGGAGA TGCAGAAGAA GACTCGGAGT TAGCAAAGCC AGGTGAAAAG 
GAAGGATGGA GAAATTCAAT GGAGAAACAG TCTTTGGTCT GGAAGAACAC CTTTTGGCAA 
GGAGACATTG ACAATTTCCA TGACGACGTC ACTCTGAGAA ACCAACGGTT CATTCCATTC 
TTGAATCCCA GAACACCCAG GAAGCTAACA CCTTACACGG TGGTGCTGCA CGGCCCCGCA 
GGCGTGGGGA AAACCACGCT GGCCAAAAAG TGTATGCTGG ACTGGACAGA CTGCAACCTC 
AGCCCGACGC TCAGATACGC GTTCTACCTC AGCTGCAAGG AGCTCAGCCG CATGGGCCCC 
TGCAGTTTTG CAGAGCTGAT CTCCAAAGAC TGGCCTGAAT TGCAGGATGA CATTCCAAGC 
ATCCTAGCCC AAGCACAGAG AATCCTGTTC GTGGTCGATG GCCTTGATGA GCTGAAAGTC 
CCACCTGGGG CGCTGATCCA GGACATCTGC GGGGACTGGG AGAAGAAGAA GCCGGTGCCC 
GTCCTCCTGG GGAGTTTGCT GAAGAGGAAG ATGTTACCCA GGGCAGCCTT GCTGGTCACC 
ACGCGGCCCA GGGCACTGAG GGACCTCCAG CTCCTGGCGC AGCAGCCGAT CTACGTAAGG 
GTGGAGGGCT TCCTGGAGGA GGACAGGAGG GCCTATTTCC TGAGACACTT TGGAGACGAG 
GACCAAGCCA TGCGTGCCTT TGAGCTAATG AGGAGCAACG CGGCCCTGTT CCAGCTGGGC 
TCGGCCCCCG CGGTGTGCTG GATTGTGTGC ACGACTCTGA AGCTGCAGAT GGAGAAGGGG 
GAGGACCCGG TCCCCACCTG CCTCACCCGC ACGGGGCTGT TCCTGCGTTT CCTCTGCAGC 
CGGTTCCCGC AGGGCGCACA GCTGCGGGGC GCGCTGCGGA CGCTGAGCCT CCTGGCCGCG 
CAGGGCCTGT GGGCGCAGAT GTCCGTGTTC CACCGAGAGG ACCTGGAAAG GCTCGGGGTG 
CAGGAGTCCG ACCTCCGTCT GTTCCTGGAC GGAGACATCC TCCGCCAGGA CAGAGTCTCC 
AAAGGCTGCT ACTCCTTCAT CCACCTCAGC TTCCAGCAGT TTCTCACTGC CCTGTTCTAC 
GCCCTGGAGA AGGAGGAGGG GGAGGACAGG GACGGCCACG CCTGGGACAT CGGGGACGTA 
CAGAAGCTGC TTTCCGGAGA AGAAAGACTC AAGAACCCCG ACCTGATTCA AGTAGGACAC 
TTCTTATTCG GCCTCGCTAA CGAGAAGAGA GCCAAGGAGT TGGAGGCCAC TTTTGGCTGC 
CGGATGTCAC CGGACATCAA ACAGGAATTG CTGCAATGCA AAGCACATCT TCATGCAAAT 
AAGCCCTTAT CCGTGACCGA CCTGAAGGAG GTCTTGGGCT GCCTGTATGA GTCTCAGGAG 
GAGGAGCTGG CGAAGGTGGT GGTGGCCCCG TTCAAGGAAA TTTCTATTCA CCTGACAAAT 
ACTTCTGAAG TGATGCATTG TTCCTTCAGC CTGAAGCATT GTCAAGACTT GCAGAAACTC 
TCACTGCAGG TAGCAAAGGG GGTGTTCCTG GAGAATTACA TGGATTTTGA ACTGGACATT 
GAATTTGAAA GGTGCACTTA CCTAACCATT CCGAACTGGG CTCGGCAGGA TCTTCGCTCT 
CTTCGCCTCT GGACAGATTT CTGCTCTCTC TTCAGCTCAA ACAGCAACCT CAAGTTTCTG 
GAAGTGAAAC AAAGCTTCCT GAGTGACTCT TCTGTGCGGA TTCTTTGTGA CCACGTAACC 
CGTAGCACCT GTCATCTGCA GAAAGTGGAG ATTAAAAACG TCACCCCTGA CACCGCGTAC 
CGGGACTTCT GTCTTGCTTT CATTGGGAAG AAGACCCTCA CGCACCTGAC CCTGGCAGGG 
CACATCGAGT GGGAACGCAC GATGATGCTG ATGCTGTGTG ACCTGCTCAG AAATCATAAA 
TGCAACCTGC AGTACCTGAG GTTGGGAGGT CACTGTGCCA CCCCGGAGCA GTGGGCTGAA 
TTCTTCTATG TCCTCAAAGC CAACCAGTCC CTGAAGCACC TGCGTCTCTC AGCCAATGTG 
CTCCTGGATG AGGGTGCCAT GTTGCTGTAC AAGACCATGA CACGCCCAAA ACACTTCCTG 
CAGATGTTGT CGTTGGAAAA CTGTCGTCTT ACAGAAGCCA GTTGCAAGGA CCTTGCTGCT 
GTCTTGGTTG TCAGCAAGAA GCTGACACAC CTGTGCTTGG CCAAGAACCC CATTGGGGAT 
ACAGGGGTGA AGTTTCTGTG TGAGGGCTTG AGTTACCCTG ATTGTAAACT GCAGACCTTG 
GTGTTACAGC AATGCAGCAT AACCAAGCTT GGCTGTAGAT ATCTCTCAGA GGCGCTCCAA 
GAAGCCTGCA GCCTCACAAA CCTGGACTTG AGTATCAACC AGATAGCTCG TGGATTGTGG 
ATTCTCTGTC AGGCATTAGA GAATCCAAAC TGTAACCTAA AACACCTACG CCTCTGGAGC 
TGCTCCCTCA TGCCTTTCTA TTGTCAGCAT CTTGGATCTG CTCTCCTCAG CAATCAGAAG 
CTTGAAACTC TGGACCTGGG CCAGAATCAT TTGTGGAAGA GTGGCATAAT TAAGCTCTTT 
GGGGTTCTAA GACAAAGAAC TGGATCCTTG AAGATACTCA GGTTGAAGAC CTATGAAACT 
AATTTGGAAA TCAAGAAGCT GTTGGAGGAA GTGAAAGAAA AGAATCCCAA GCTGACTATT 
GATTGCAATG CTTCCGGGGC AACGGCACCT CCGTGCTGTG ACTTTTTTTG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001120727.1
CDS	77..3190
Translation	MTSPQLEWTLQTLLEQLNEDELKSFKSLLWAFPLEDVLQKTPWSEVEEADGKKLAEILVNTSSENWIRNATVNILEEMNLTELCKMAKAEMMEDGQVQEIDNPELGDAEEDSELAKPGEKEGWRNSMEKQSLVWKNTFWQGDIDNFHDDVTLRNQRFIPFLNPRTPRKLTPYTVVLHGPAGVGKTTLAKKCMLDWTDCNLSPTLRYAFYLSCKELSRMGPCSFAELISKDWPELQDDIPSILAQAQRILFVVDGLDELKVPPGALIQDICGDWEKKKPVPVLLGSLLKRKMLPRAALLVTTRPRALRDLQLLAQQPIYVRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQGAQLRGALRTLSLLAAQGLWAQMSVFHREDLERLGVQESDLRLFLDGDILRQDRVSKGCYSFIHLSFQQFLTALFYALEKEEGEDRDGHAWDIGDVQKLLSGEERLKNPDLIQVGHFLFGLANEKRAKELEATFGCRMSPDIKQELLQCKAHLHANKPLSVTDLKEVLGCLYESQEEELAKVVVAPFKEISIHLTNTSEVMHCSFSLKHCQDLQKLSLQVAKGVFLENYMDFELDIEFERCTYLTIPNWARQDLRSLRLWTDFCSLFSSNSNLKFLEVKQSFLSDSSVRILCDHVTRSTCHLQKVEIKNVTPDTAYRDFCLAFIGKKTLTHLTLAGHIEWERTMMLMLCDLLRNHKCNLQYLRLGGHCATPEQWAEFFYVLKANQSLKHLRLSANVLLDEGAMLLYKTMTRPKHFLQMLSLENCRLTEASCKDLAAVLVVSKKLTHLCLAKNPIGDTGVKFLCEGLSYPDCKLQTLVLQQCSITKLGCRYLSEALQEACSLTNLDLSINQIARGLWILCQALENPNCNLKHLRLWSCSLMPFYCQHLGSALLSNQKLETLDLGQNHLWKSGIIKLFGVLRQRTGSLKILRLKTYETNLEIKKLLEEVKEKNPKLTIDCNASGATAPPCCDFFC

Target ORF information:

RefSeq Version	NM_001127255.1
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001127255.1

ORF Insert Sequence:

ATGACATCGC CCCAGCTAGA GTGGACTCTG CAGACCCTTC TGGAGCAGCT GAACGAGGAT 
GAATTAAAGA GTTTCAAATC CCTTTTATGG GCTTTTCCCC TCGAAGACGT GCTACAGAAG 
ACCCCATGGT CTGAGGTGGA AGAGGCTGAT GGCAAGAAAC TGGCAGAAAT TCTGGTCAAC 
ACCTCCTCAG AAAATTGGAT AAGGAATGCG ACTGTGAACA TCTTGGAAGA GATGAATCTC 
ACGGAATTGT GTAAGATGGC AAAGGCTGAG ATGATGGAGG ACGGACAGGT GCAAGAAATA 
GATAATCCTG AGCTGGGAGA TGCAGAAGAA GACTCGGAGT TAGCAAAGCC AGGTGAAAAG 
GAAGGATGGA GAAATTCAAT GGAGAAACAG TCTTTGGTCT GGAAGAACAC CTTTTGGCAA 
GGAGACATTG ACAATTTCCA TGACGACGTC ACTCTGAGAA ACCAACGGTT CATTCCATTC 
TTGAATCCCA GAACACCCAG GAAGCTAACA CCTTACACGG TGGTGCTGCA CGGCCCCGCA 
GGCGTGGGGA AAACCACGCT GGCCAAAAAG TGTATGCTGG ACTGGACAGA CTGCAACCTC 
AGCCCGACGC TCAGATACGC GTTCTACCTC AGCTGCAAGG AGCTCAGCCG CATGGGCCCC 
TGCAGTTTTG CAGAGCTGAT CTCCAAAGAC TGGCCTGAAT TGCAGGATGA CATTCCAAGC 
ATCCTAGCCC AAGCACAGAG AATCCTGTTC GTGGTCGATG GCCTTGATGA GCTGAAAGTC 
CCACCTGGGG CGCTGATCCA GGACATCTGC GGGGACTGGG AGAAGAAGAA GCCGGTGCCC 
GTCCTCCTGG GGAGTTTGCT GAAGAGGAAG ATGTTACCCA GGGCAGCCTT GCTGGTCACC 
ACGCGGCCCA GGGCACTGAG GGACCTCCAG CTCCTGGCGC AGCAGCCGAT CTACGTAAGG 
GTGGAGGGCT TCCTGGAGGA GGACAGGAGG GCCTATTTCC TGAGACACTT TGGAGACGAG 
GACCAAGCCA TGCGTGCCTT TGAGCTAATG AGGAGCAACG CGGCCCTGTT CCAGCTGGGC 
TCGGCCCCCG CGGTGTGCTG GATTGTGTGC ACGACTCTGA AGCTGCAGAT GGAGAAGGGG 
GAGGACCCGG TCCCCACCTG CCTCACCCGC ACGGGGCTGT TCCTGCGTTT CCTCTGCAGC 
CGGTTCCCGC AGGGCGCACA GCTGCGGGGC GCGCTGCGGA CGCTGAGCCT CCTGGCCGCG 
CAGGGCCTGT GGGCGCAGAT GTCCGTGTTC CACCGAGAGG ACCTGGAAAG GCTCGGGGTG 
CAGGAGTCCG ACCTCCGTCT GTTCCTGGAC GGAGACATCC TCCGCCAGGA CAGAGTCTCC 
AAAGGCTGCT ACTCCTTCAT CCACCTCAGC TTCCAGCAGT TTCTCACTGC CCTGTTCTAC 
GCCCTGGAGA AGGAGGAGGG GGAGGACAGG GACGGCCACG CCTGGGACAT CGGGGACGTA 
CAGAAGCTGC TTTCCGGAGA AGAAAGACTC AAGAACCCCG ACCTGATTCA AGTAGGACAC 
TTCTTATTCG GCCTCGCTAA CGAGAAGAGA GCCAAGGAGT TGGAGGCCAC TTTTGGCTGC 
CGGATGTCAC CGGACATCAA ACAGGAATTG CTGCAATGCA AAGCACATCT TCATGCAAAT 
AAGCCCTTAT CCGTGACCGA CCTGAAGGAG GTCTTGGGCT GCCTGTATGA GTCTCAGGAG 
GAGGAGCTGG CGAAGGTGGT GGTGGCCCCG TTCAAGGAAA TTTCTATTCA CCTGACAAAT 
ACTTCTGAAG TGATGCATTG TTCCTTCAGC CTGAAGCATT GTCAAGACTT GCAGAAACTC 
TCACTGCAGG TAGCAAAGGG GGTGTTCCTG GAGAATTACA TGGATTTTGA ACTGGACATT 
GAATTTGAAA GGTGCACTTA CCTAACCATT CCGAACTGGG CTCGGCAGGA TCTTCGCTCT 
CTTCGCCTCT GGACAGATTT CTGCTCTCTC TTCAGCTCAA ACAGCAACCT CAAGTTTCTG 
GAAGTGAAAC AAAGCTTCCT GAGTGACTCT TCTGTGCGGA TTCTTTGTGA CCACGTAACC 
CGTAGCACCT GTCATCTGCA GAAAGTGGAG ATTAAAAACG TCACCCCTGA CACCGCGTAC 
CGGGACTTCT GTCTTGCTTT CATTGGGAAG AAGACCCTCA CGCACCTGAC CCTGGCAGGG 
CACATCGAGT GGGAACGCAC GATGATGCTG ATGCTGTGTG ACCTGCTCAG AAATCATAAA 
TGCAACCTGC AGTACCTGAG GTTGGGAGGT CACTGTGCCA CCCCGGAGCA GTGGGCTGAA 
TTCTTCTATG TCCTCAAAGC CAACCAGTCC CTGAAGCACC TGCGTCTCTC AGCCAATGTG 
CTCCTGGATG AGGGTGCCAT GTTGCTGTAC AAGACCATGA CACGCCCAAA ACACTTCCTG 
CAGATGTTGT CGTTGGAAAA CTGTCGTCTT ACAGAAGCCA GTTGCAAGGA CCTTGCTGCT 
GTCTTGGTTG TCAGCAAGAA GCTGACACAC CTGTGCTTGG CCAAGAACCC CATTGGGGAT 
ACAGGGGTGA AGTTTCTGTG TGAGGGCTTG AGTTACCCTG ATTGTAAACT GCAGACCTTG 
GTGTTACAGC AATGCAGCAT AACCAAGCTT GGCTGTAGAT ATCTCTCAGA GGCGCTCCAA 
GAAGCCTGCA GCCTCACAAA CCTGGACTTG AGTATCAACC AGATAGCTCG TGGATTGTGG 
ATTCTCTGTC AGGCATTAGA GAATCCAAAC TGTAACCTAA AACACCTACG CCTCTGGAGC 
TGCTCCCTCA TGCCTTTCTA TTGTCAGCAT CTTGGATCTG CTCTCCTCAG CAATCAGAAG 
CTTGAAACTC TGGACCTGGG CCAGAATCAT TTGTGGAAGA GTGGCATAAT TAAGCTCTTT 
GGGGTTCTAA GACAAAGAAC TGGATCCTTG AAGATACTCA GGTTGAAGAC CTATGAAACT 
AATTTGGAAA TCAAGAAGCT GTTGGAGGAA GTGAAAGAAA AGAATCCCAA GCTGACTATT 
GATTGCAATG CTTCCGGGGC AACGGCACCT CCGTGCTGTG ACTTTTTTTG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP7 ( XM_006723075.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006723138.1 Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu18156
Clone ID Related Accession (Same CDS sequence)	XM_006723075.3 , NM_001127255.1 , XM_006723076.3 , XM_011526599.2
Accession Version	XM_006723075.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3114bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 7 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006723075.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACATCGC CCCAGCTAGA GTGGACTCTG CAGACCCTTC TGGAGCAGCT GAACGAGGAT 
GAATTAAAGA GTTTCAAATC CCTTTTATGG GCTTTTCCCC TCGAAGACGT GCTACAGAAG 
ACCCCATGGT CTGAGGTGGA AGAGGCTGAT GGCAAGAAAC TGGCAGAAAT TCTGGTCAAC 
ACCTCCTCAG AAAATTGGAT AAGGAATGCG ACTGTGAACA TCTTGGAAGA GATGAATCTC 
ACGGAATTGT GTAAGATGGC AAAGGCTGAG ATGATGGAGG ACGGACAGGT GCAAGAAATA 
GATAATCCTG AGCTGGGAGA TGCAGAAGAA GACTCGGAGT TAGCAAAGCC AGGTGAAAAG 
GAAGGATGGA GAAATTCAAT GGAGAAACAG TCTTTGGTCT GGAAGAACAC CTTTTGGCAA 
GGAGACATTG ACAATTTCCA TGACGACGTC ACTCTGAGAA ACCAACGGTT CATTCCATTC 
TTGAATCCCA GAACACCCAG GAAGCTAACA CCTTACACGG TGGTGCTGCA CGGCCCCGCA 
GGCGTGGGGA AAACCACGCT GGCCAAAAAG TGTATGCTGG ACTGGACAGA CTGCAACCTC 
AGCCCGACGC TCAGATACGC GTTCTACCTC AGCTGCAAGG AGCTCAGCCG CATGGGCCCC 
TGCAGTTTTG CAGAGCTGAT CTCCAAAGAC TGGCCTGAAT TGCAGGATGA CATTCCAAGC 
ATCCTAGCCC AAGCACAGAG AATCCTGTTC GTGGTCGATG GCCTTGATGA GCTGAAAGTC 
CCACCTGGGG CGCTGATCCA GGACATCTGC GGGGACTGGG AGAAGAAGAA GCCGGTGCCC 
GTCCTCCTGG GGAGTTTGCT GAAGAGGAAG ATGTTACCCA GGGCAGCCTT GCTGGTCACC 
ACGCGGCCCA GGGCACTGAG GGACCTCCAG CTCCTGGCGC AGCAGCCGAT CTACGTAAGG 
GTGGAGGGCT TCCTGGAGGA GGACAGGAGG GCCTATTTCC TGAGACACTT TGGAGACGAG 
GACCAAGCCA TGCGTGCCTT TGAGCTAATG AGGAGCAACG CGGCCCTGTT CCAGCTGGGC 
TCGGCCCCCG CGGTGTGCTG GATTGTGTGC ACGACTCTGA AGCTGCAGAT GGAGAAGGGG 
GAGGACCCGG TCCCCACCTG CCTCACCCGC ACGGGGCTGT TCCTGCGTTT CCTCTGCAGC 
CGGTTCCCGC AGGGCGCACA GCTGCGGGGC GCGCTGCGGA CGCTGAGCCT CCTGGCCGCG 
CAGGGCCTGT GGGCGCAGAT GTCCGTGTTC CACCGAGAGG ACCTGGAAAG GCTCGGGGTG 
CAGGAGTCCG ACCTCCGTCT GTTCCTGGAC GGAGACATCC TCCGCCAGGA CAGAGTCTCC 
AAAGGCTGCT ACTCCTTCAT CCACCTCAGC TTCCAGCAGT TTCTCACTGC CCTGTTCTAC 
GCCCTGGAGA AGGAGGAGGG GGAGGACAGG GACGGCCACG CCTGGGACAT CGGGGACGTA 
CAGAAGCTGC TTTCCGGAGA AGAAAGACTC AAGAACCCCG ACCTGATTCA AGTAGGACAC 
TTCTTATTCG GCCTCGCTAA CGAGAAGAGA GCCAAGGAGT TGGAGGCCAC TTTTGGCTGC 
CGGATGTCAC CGGACATCAA ACAGGAATTG CTGCAATGCA AAGCACATCT TCATGCAAAT 
AAGCCCTTAT CCGTGACCGA CCTGAAGGAG GTCTTGGGCT GCCTGTATGA GTCTCAGGAG 
GAGGAGCTGG CGAAGGTGGT GGTGGCCCCG TTCAAGGAAA TTTCTATTCA CCTGACAAAT 
ACTTCTGAAG TGATGCATTG TTCCTTCAGC CTGAAGCATT GTCAAGACTT GCAGAAACTC 
TCACTGCAGG TAGCAAAGGG GGTGTTCCTG GAGAATTACA TGGATTTTGA ACTGGACATT 
GAATTTGAAA GGTGCACTTA CCTAACCATT CCGAACTGGG CTCGGCAGGA TCTTCGCTCT 
CTTCGCCTCT GGACAGATTT CTGCTCTCTC TTCAGCTCAA ACAGCAACCT CAAGTTTCTG 
GAAGTGAAAC AAAGCTTCCT GAGTGACTCT TCTGTGCGGA TTCTTTGTGA CCACGTAACC 
CGTAGCACCT GTCATCTGCA GAAAGTGGAG ATTAAAAACG TCACCCCTGA CACCGCGTAC 
CGGGACTTCT GTCTTGCTTT CATTGGGAAG AAGACCCTCA CGCACCTGAC CCTGGCAGGG 
CACATCGAGT GGGAACGCAC GATGATGCTG ATGCTGTGTG ACCTGCTCAG AAATCATAAA 
TGCAACCTGC AGTACCTGAG GTTGGGAGGT CACTGTGCCA CCCCGGAGCA GTGGGCTGAA 
TTCTTCTATG TCCTCAAAGC CAACCAGTCC CTGAAGCACC TGCGTCTCTC AGCCAATGTG 
CTCCTGGATG AGGGTGCCAT GTTGCTGTAC AAGACCATGA CACGCCCAAA ACACTTCCTG 
CAGATGTTGT CGTTGGAAAA CTGTCGTCTT ACAGAAGCCA GTTGCAAGGA CCTTGCTGCT 
GTCTTGGTTG TCAGCAAGAA GCTGACACAC CTGTGCTTGG CCAAGAACCC CATTGGGGAT 
ACAGGGGTGA AGTTTCTGTG TGAGGGCTTG AGTTACCCTG ATTGTAAACT GCAGACCTTG 
GTGTTACAGC AATGCAGCAT AACCAAGCTT GGCTGTAGAT ATCTCTCAGA GGCGCTCCAA 
GAAGCCTGCA GCCTCACAAA CCTGGACTTG AGTATCAACC AGATAGCTCG TGGATTGTGG 
ATTCTCTGTC AGGCATTAGA GAATCCAAAC TGTAACCTAA AACACCTACG CCTCTGGAGC 
TGCTCCCTCA TGCCTTTCTA TTGTCAGCAT CTTGGATCTG CTCTCCTCAG CAATCAGAAG 
CTTGAAACTC TGGACCTGGG CCAGAATCAT TTGTGGAAGA GTGGCATAAT TAAGCTCTTT 
GGGGTTCTAA GACAAAGAAC TGGATCCTTG AAGATACTCA GGTTGAAGAC CTATGAAACT 
AATTTGGAAA TCAAGAAGCT GTTGGAGGAA GTGAAAGAAA AGAATCCCAA GCTGACTATT 
GATTGCAATG CTTCCGGGGC AACGGCACCT CCGTGCTGTG ACTTTTTTTG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006723138.1
CDS	312..3425
Translation	MTSPQLEWTLQTLLEQLNEDELKSFKSLLWAFPLEDVLQKTPWSEVEEADGKKLAEILVNTSSENWIRNATVNILEEMNLTELCKMAKAEMMEDGQVQEIDNPELGDAEEDSELAKPGEKEGWRNSMEKQSLVWKNTFWQGDIDNFHDDVTLRNQRFIPFLNPRTPRKLTPYTVVLHGPAGVGKTTLAKKCMLDWTDCNLSPTLRYAFYLSCKELSRMGPCSFAELISKDWPELQDDIPSILAQAQRILFVVDGLDELKVPPGALIQDICGDWEKKKPVPVLLGSLLKRKMLPRAALLVTTRPRALRDLQLLAQQPIYVRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQGAQLRGALRTLSLLAAQGLWAQMSVFHREDLERLGVQESDLRLFLDGDILRQDRVSKGCYSFIHLSFQQFLTALFYALEKEEGEDRDGHAWDIGDVQKLLSGEERLKNPDLIQVGHFLFGLANEKRAKELEATFGCRMSPDIKQELLQCKAHLHANKPLSVTDLKEVLGCLYESQEEELAKVVVAPFKEISIHLTNTSEVMHCSFSLKHCQDLQKLSLQVAKGVFLENYMDFELDIEFERCTYLTIPNWARQDLRSLRLWTDFCSLFSSNSNLKFLEVKQSFLSDSSVRILCDHVTRSTCHLQKVEIKNVTPDTAYRDFCLAFIGKKTLTHLTLAGHIEWERTMMLMLCDLLRNHKCNLQYLRLGGHCATPEQWAEFFYVLKANQSLKHLRLSANVLLDEGAMLLYKTMTRPKHFLQMLSLENCRLTEASCKDLAAVLVVSKKLTHLCLAKNPIGDTGVKFLCEGLSYPDCKLQTLVLQQCSITKLGCRYLSEALQEACSLTNLDLSINQIARGLWILCQALENPNCNLKHLRLWSCSLMPFYCQHLGSALLSNQKLETLDLGQNHLWKSGIIKLFGVLRQRTGSLKILRLKTYETNLEIKKLLEEVKEKNPKLTIDCNASGATAPPCCDFFC

Target ORF information:

RefSeq Version	XM_006723075.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006723075.3

ORF Insert Sequence:

ATGACATCGC CCCAGCTAGA GTGGACTCTG CAGACCCTTC TGGAGCAGCT GAACGAGGAT 
GAATTAAAGA GTTTCAAATC CCTTTTATGG GCTTTTCCCC TCGAAGACGT GCTACAGAAG 
ACCCCATGGT CTGAGGTGGA AGAGGCTGAT GGCAAGAAAC TGGCAGAAAT TCTGGTCAAC 
ACCTCCTCAG AAAATTGGAT AAGGAATGCG ACTGTGAACA TCTTGGAAGA GATGAATCTC 
ACGGAATTGT GTAAGATGGC AAAGGCTGAG ATGATGGAGG ACGGACAGGT GCAAGAAATA 
GATAATCCTG AGCTGGGAGA TGCAGAAGAA GACTCGGAGT TAGCAAAGCC AGGTGAAAAG 
GAAGGATGGA GAAATTCAAT GGAGAAACAG TCTTTGGTCT GGAAGAACAC CTTTTGGCAA 
GGAGACATTG ACAATTTCCA TGACGACGTC ACTCTGAGAA ACCAACGGTT CATTCCATTC 
TTGAATCCCA GAACACCCAG GAAGCTAACA CCTTACACGG TGGTGCTGCA CGGCCCCGCA 
GGCGTGGGGA AAACCACGCT GGCCAAAAAG TGTATGCTGG ACTGGACAGA CTGCAACCTC 
AGCCCGACGC TCAGATACGC GTTCTACCTC AGCTGCAAGG AGCTCAGCCG CATGGGCCCC 
TGCAGTTTTG CAGAGCTGAT CTCCAAAGAC TGGCCTGAAT TGCAGGATGA CATTCCAAGC 
ATCCTAGCCC AAGCACAGAG AATCCTGTTC GTGGTCGATG GCCTTGATGA GCTGAAAGTC 
CCACCTGGGG CGCTGATCCA GGACATCTGC GGGGACTGGG AGAAGAAGAA GCCGGTGCCC 
GTCCTCCTGG GGAGTTTGCT GAAGAGGAAG ATGTTACCCA GGGCAGCCTT GCTGGTCACC 
ACGCGGCCCA GGGCACTGAG GGACCTCCAG CTCCTGGCGC AGCAGCCGAT CTACGTAAGG 
GTGGAGGGCT TCCTGGAGGA GGACAGGAGG GCCTATTTCC TGAGACACTT TGGAGACGAG 
GACCAAGCCA TGCGTGCCTT TGAGCTAATG AGGAGCAACG CGGCCCTGTT CCAGCTGGGC 
TCGGCCCCCG CGGTGTGCTG GATTGTGTGC ACGACTCTGA AGCTGCAGAT GGAGAAGGGG 
GAGGACCCGG TCCCCACCTG CCTCACCCGC ACGGGGCTGT TCCTGCGTTT CCTCTGCAGC 
CGGTTCCCGC AGGGCGCACA GCTGCGGGGC GCGCTGCGGA CGCTGAGCCT CCTGGCCGCG 
CAGGGCCTGT GGGCGCAGAT GTCCGTGTTC CACCGAGAGG ACCTGGAAAG GCTCGGGGTG 
CAGGAGTCCG ACCTCCGTCT GTTCCTGGAC GGAGACATCC TCCGCCAGGA CAGAGTCTCC 
AAAGGCTGCT ACTCCTTCAT CCACCTCAGC TTCCAGCAGT TTCTCACTGC CCTGTTCTAC 
GCCCTGGAGA AGGAGGAGGG GGAGGACAGG GACGGCCACG CCTGGGACAT CGGGGACGTA 
CAGAAGCTGC TTTCCGGAGA AGAAAGACTC AAGAACCCCG ACCTGATTCA AGTAGGACAC 
TTCTTATTCG GCCTCGCTAA CGAGAAGAGA GCCAAGGAGT TGGAGGCCAC TTTTGGCTGC 
CGGATGTCAC CGGACATCAA ACAGGAATTG CTGCAATGCA AAGCACATCT TCATGCAAAT 
AAGCCCTTAT CCGTGACCGA CCTGAAGGAG GTCTTGGGCT GCCTGTATGA GTCTCAGGAG 
GAGGAGCTGG CGAAGGTGGT GGTGGCCCCG TTCAAGGAAA TTTCTATTCA CCTGACAAAT 
ACTTCTGAAG TGATGCATTG TTCCTTCAGC CTGAAGCATT GTCAAGACTT GCAGAAACTC 
TCACTGCAGG TAGCAAAGGG GGTGTTCCTG GAGAATTACA TGGATTTTGA ACTGGACATT 
GAATTTGAAA GGTGCACTTA CCTAACCATT CCGAACTGGG CTCGGCAGGA TCTTCGCTCT 
CTTCGCCTCT GGACAGATTT CTGCTCTCTC TTCAGCTCAA ACAGCAACCT CAAGTTTCTG 
GAAGTGAAAC AAAGCTTCCT GAGTGACTCT TCTGTGCGGA TTCTTTGTGA CCACGTAACC 
CGTAGCACCT GTCATCTGCA GAAAGTGGAG ATTAAAAACG TCACCCCTGA CACCGCGTAC 
CGGGACTTCT GTCTTGCTTT CATTGGGAAG AAGACCCTCA CGCACCTGAC CCTGGCAGGG 
CACATCGAGT GGGAACGCAC GATGATGCTG ATGCTGTGTG ACCTGCTCAG AAATCATAAA 
TGCAACCTGC AGTACCTGAG GTTGGGAGGT CACTGTGCCA CCCCGGAGCA GTGGGCTGAA 
TTCTTCTATG TCCTCAAAGC CAACCAGTCC CTGAAGCACC TGCGTCTCTC AGCCAATGTG 
CTCCTGGATG AGGGTGCCAT GTTGCTGTAC AAGACCATGA CACGCCCAAA ACACTTCCTG 
CAGATGTTGT CGTTGGAAAA CTGTCGTCTT ACAGAAGCCA GTTGCAAGGA CCTTGCTGCT 
GTCTTGGTTG TCAGCAAGAA GCTGACACAC CTGTGCTTGG CCAAGAACCC CATTGGGGAT 
ACAGGGGTGA AGTTTCTGTG TGAGGGCTTG AGTTACCCTG ATTGTAAACT GCAGACCTTG 
GTGTTACAGC AATGCAGCAT AACCAAGCTT GGCTGTAGAT ATCTCTCAGA GGCGCTCCAA 
GAAGCCTGCA GCCTCACAAA CCTGGACTTG AGTATCAACC AGATAGCTCG TGGATTGTGG 
ATTCTCTGTC AGGCATTAGA GAATCCAAAC TGTAACCTAA AACACCTACG CCTCTGGAGC 
TGCTCCCTCA TGCCTTTCTA TTGTCAGCAT CTTGGATCTG CTCTCCTCAG CAATCAGAAG 
CTTGAAACTC TGGACCTGGG CCAGAATCAT TTGTGGAAGA GTGGCATAAT TAAGCTCTTT 
GGGGTTCTAA GACAAAGAAC TGGATCCTTG AAGATACTCA GGTTGAAGAC CTATGAAACT 
AATTTGGAAA TCAAGAAGCT GTTGGAGGAA GTGAAAGAAA AGAATCCCAA GCTGACTATT 
GATTGCAATG CTTCCGGGGC AACGGCACCT CCGTGCTGTG ACTTTTTTTG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP7 ( XM_006723076.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006723139.1 Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant X4, mRNA.

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CloneID	OHu18156
Clone ID Related Accession (Same CDS sequence)	XM_006723075.3 , NM_001127255.1 , XM_006723076.3 , XM_011526599.2
Accession Version	XM_006723076.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3114bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 7 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006723076.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACATCGC CCCAGCTAGA GTGGACTCTG CAGACCCTTC TGGAGCAGCT GAACGAGGAT 
GAATTAAAGA GTTTCAAATC CCTTTTATGG GCTTTTCCCC TCGAAGACGT GCTACAGAAG 
ACCCCATGGT CTGAGGTGGA AGAGGCTGAT GGCAAGAAAC TGGCAGAAAT TCTGGTCAAC 
ACCTCCTCAG AAAATTGGAT AAGGAATGCG ACTGTGAACA TCTTGGAAGA GATGAATCTC 
ACGGAATTGT GTAAGATGGC AAAGGCTGAG ATGATGGAGG ACGGACAGGT GCAAGAAATA 
GATAATCCTG AGCTGGGAGA TGCAGAAGAA GACTCGGAGT TAGCAAAGCC AGGTGAAAAG 
GAAGGATGGA GAAATTCAAT GGAGAAACAG TCTTTGGTCT GGAAGAACAC CTTTTGGCAA 
GGAGACATTG ACAATTTCCA TGACGACGTC ACTCTGAGAA ACCAACGGTT CATTCCATTC 
TTGAATCCCA GAACACCCAG GAAGCTAACA CCTTACACGG TGGTGCTGCA CGGCCCCGCA 
GGCGTGGGGA AAACCACGCT GGCCAAAAAG TGTATGCTGG ACTGGACAGA CTGCAACCTC 
AGCCCGACGC TCAGATACGC GTTCTACCTC AGCTGCAAGG AGCTCAGCCG CATGGGCCCC 
TGCAGTTTTG CAGAGCTGAT CTCCAAAGAC TGGCCTGAAT TGCAGGATGA CATTCCAAGC 
ATCCTAGCCC AAGCACAGAG AATCCTGTTC GTGGTCGATG GCCTTGATGA GCTGAAAGTC 
CCACCTGGGG CGCTGATCCA GGACATCTGC GGGGACTGGG AGAAGAAGAA GCCGGTGCCC 
GTCCTCCTGG GGAGTTTGCT GAAGAGGAAG ATGTTACCCA GGGCAGCCTT GCTGGTCACC 
ACGCGGCCCA GGGCACTGAG GGACCTCCAG CTCCTGGCGC AGCAGCCGAT CTACGTAAGG 
GTGGAGGGCT TCCTGGAGGA GGACAGGAGG GCCTATTTCC TGAGACACTT TGGAGACGAG 
GACCAAGCCA TGCGTGCCTT TGAGCTAATG AGGAGCAACG CGGCCCTGTT CCAGCTGGGC 
TCGGCCCCCG CGGTGTGCTG GATTGTGTGC ACGACTCTGA AGCTGCAGAT GGAGAAGGGG 
GAGGACCCGG TCCCCACCTG CCTCACCCGC ACGGGGCTGT TCCTGCGTTT CCTCTGCAGC 
CGGTTCCCGC AGGGCGCACA GCTGCGGGGC GCGCTGCGGA CGCTGAGCCT CCTGGCCGCG 
CAGGGCCTGT GGGCGCAGAT GTCCGTGTTC CACCGAGAGG ACCTGGAAAG GCTCGGGGTG 
CAGGAGTCCG ACCTCCGTCT GTTCCTGGAC GGAGACATCC TCCGCCAGGA CAGAGTCTCC 
AAAGGCTGCT ACTCCTTCAT CCACCTCAGC TTCCAGCAGT TTCTCACTGC CCTGTTCTAC 
GCCCTGGAGA AGGAGGAGGG GGAGGACAGG GACGGCCACG CCTGGGACAT CGGGGACGTA 
CAGAAGCTGC TTTCCGGAGA AGAAAGACTC AAGAACCCCG ACCTGATTCA AGTAGGACAC 
TTCTTATTCG GCCTCGCTAA CGAGAAGAGA GCCAAGGAGT TGGAGGCCAC TTTTGGCTGC 
CGGATGTCAC CGGACATCAA ACAGGAATTG CTGCAATGCA AAGCACATCT TCATGCAAAT 
AAGCCCTTAT CCGTGACCGA CCTGAAGGAG GTCTTGGGCT GCCTGTATGA GTCTCAGGAG 
GAGGAGCTGG CGAAGGTGGT GGTGGCCCCG TTCAAGGAAA TTTCTATTCA CCTGACAAAT 
ACTTCTGAAG TGATGCATTG TTCCTTCAGC CTGAAGCATT GTCAAGACTT GCAGAAACTC 
TCACTGCAGG TAGCAAAGGG GGTGTTCCTG GAGAATTACA TGGATTTTGA ACTGGACATT 
GAATTTGAAA GGTGCACTTA CCTAACCATT CCGAACTGGG CTCGGCAGGA TCTTCGCTCT 
CTTCGCCTCT GGACAGATTT CTGCTCTCTC TTCAGCTCAA ACAGCAACCT CAAGTTTCTG 
GAAGTGAAAC AAAGCTTCCT GAGTGACTCT TCTGTGCGGA TTCTTTGTGA CCACGTAACC 
CGTAGCACCT GTCATCTGCA GAAAGTGGAG ATTAAAAACG TCACCCCTGA CACCGCGTAC 
CGGGACTTCT GTCTTGCTTT CATTGGGAAG AAGACCCTCA CGCACCTGAC CCTGGCAGGG 
CACATCGAGT GGGAACGCAC GATGATGCTG ATGCTGTGTG ACCTGCTCAG AAATCATAAA 
TGCAACCTGC AGTACCTGAG GTTGGGAGGT CACTGTGCCA CCCCGGAGCA GTGGGCTGAA 
TTCTTCTATG TCCTCAAAGC CAACCAGTCC CTGAAGCACC TGCGTCTCTC AGCCAATGTG 
CTCCTGGATG AGGGTGCCAT GTTGCTGTAC AAGACCATGA CACGCCCAAA ACACTTCCTG 
CAGATGTTGT CGTTGGAAAA CTGTCGTCTT ACAGAAGCCA GTTGCAAGGA CCTTGCTGCT 
GTCTTGGTTG TCAGCAAGAA GCTGACACAC CTGTGCTTGG CCAAGAACCC CATTGGGGAT 
ACAGGGGTGA AGTTTCTGTG TGAGGGCTTG AGTTACCCTG ATTGTAAACT GCAGACCTTG 
GTGTTACAGC AATGCAGCAT AACCAAGCTT GGCTGTAGAT ATCTCTCAGA GGCGCTCCAA 
GAAGCCTGCA GCCTCACAAA CCTGGACTTG AGTATCAACC AGATAGCTCG TGGATTGTGG 
ATTCTCTGTC AGGCATTAGA GAATCCAAAC TGTAACCTAA AACACCTACG CCTCTGGAGC 
TGCTCCCTCA TGCCTTTCTA TTGTCAGCAT CTTGGATCTG CTCTCCTCAG CAATCAGAAG 
CTTGAAACTC TGGACCTGGG CCAGAATCAT TTGTGGAAGA GTGGCATAAT TAAGCTCTTT 
GGGGTTCTAA GACAAAGAAC TGGATCCTTG AAGATACTCA GGTTGAAGAC CTATGAAACT 
AATTTGGAAA TCAAGAAGCT GTTGGAGGAA GTGAAAGAAA AGAATCCCAA GCTGACTATT 
GATTGCAATG CTTCCGGGGC AACGGCACCT CCGTGCTGTG ACTTTTTTTG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006723139.1
CDS	275..3388
Translation	MTSPQLEWTLQTLLEQLNEDELKSFKSLLWAFPLEDVLQKTPWSEVEEADGKKLAEILVNTSSENWIRNATVNILEEMNLTELCKMAKAEMMEDGQVQEIDNPELGDAEEDSELAKPGEKEGWRNSMEKQSLVWKNTFWQGDIDNFHDDVTLRNQRFIPFLNPRTPRKLTPYTVVLHGPAGVGKTTLAKKCMLDWTDCNLSPTLRYAFYLSCKELSRMGPCSFAELISKDWPELQDDIPSILAQAQRILFVVDGLDELKVPPGALIQDICGDWEKKKPVPVLLGSLLKRKMLPRAALLVTTRPRALRDLQLLAQQPIYVRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQGAQLRGALRTLSLLAAQGLWAQMSVFHREDLERLGVQESDLRLFLDGDILRQDRVSKGCYSFIHLSFQQFLTALFYALEKEEGEDRDGHAWDIGDVQKLLSGEERLKNPDLIQVGHFLFGLANEKRAKELEATFGCRMSPDIKQELLQCKAHLHANKPLSVTDLKEVLGCLYESQEEELAKVVVAPFKEISIHLTNTSEVMHCSFSLKHCQDLQKLSLQVAKGVFLENYMDFELDIEFERCTYLTIPNWARQDLRSLRLWTDFCSLFSSNSNLKFLEVKQSFLSDSSVRILCDHVTRSTCHLQKVEIKNVTPDTAYRDFCLAFIGKKTLTHLTLAGHIEWERTMMLMLCDLLRNHKCNLQYLRLGGHCATPEQWAEFFYVLKANQSLKHLRLSANVLLDEGAMLLYKTMTRPKHFLQMLSLENCRLTEASCKDLAAVLVVSKKLTHLCLAKNPIGDTGVKFLCEGLSYPDCKLQTLVLQQCSITKLGCRYLSEALQEACSLTNLDLSINQIARGLWILCQALENPNCNLKHLRLWSCSLMPFYCQHLGSALLSNQKLETLDLGQNHLWKSGIIKLFGVLRQRTGSLKILRLKTYETNLEIKKLLEEVKEKNPKLTIDCNASGATAPPCCDFFC

Target ORF information:

RefSeq Version	XM_006723076.3
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006723076.3

ORF Insert Sequence:

ATGACATCGC CCCAGCTAGA GTGGACTCTG CAGACCCTTC TGGAGCAGCT GAACGAGGAT 
GAATTAAAGA GTTTCAAATC CCTTTTATGG GCTTTTCCCC TCGAAGACGT GCTACAGAAG 
ACCCCATGGT CTGAGGTGGA AGAGGCTGAT GGCAAGAAAC TGGCAGAAAT TCTGGTCAAC 
ACCTCCTCAG AAAATTGGAT AAGGAATGCG ACTGTGAACA TCTTGGAAGA GATGAATCTC 
ACGGAATTGT GTAAGATGGC AAAGGCTGAG ATGATGGAGG ACGGACAGGT GCAAGAAATA 
GATAATCCTG AGCTGGGAGA TGCAGAAGAA GACTCGGAGT TAGCAAAGCC AGGTGAAAAG 
GAAGGATGGA GAAATTCAAT GGAGAAACAG TCTTTGGTCT GGAAGAACAC CTTTTGGCAA 
GGAGACATTG ACAATTTCCA TGACGACGTC ACTCTGAGAA ACCAACGGTT CATTCCATTC 
TTGAATCCCA GAACACCCAG GAAGCTAACA CCTTACACGG TGGTGCTGCA CGGCCCCGCA 
GGCGTGGGGA AAACCACGCT GGCCAAAAAG TGTATGCTGG ACTGGACAGA CTGCAACCTC 
AGCCCGACGC TCAGATACGC GTTCTACCTC AGCTGCAAGG AGCTCAGCCG CATGGGCCCC 
TGCAGTTTTG CAGAGCTGAT CTCCAAAGAC TGGCCTGAAT TGCAGGATGA CATTCCAAGC 
ATCCTAGCCC AAGCACAGAG AATCCTGTTC GTGGTCGATG GCCTTGATGA GCTGAAAGTC 
CCACCTGGGG CGCTGATCCA GGACATCTGC GGGGACTGGG AGAAGAAGAA GCCGGTGCCC 
GTCCTCCTGG GGAGTTTGCT GAAGAGGAAG ATGTTACCCA GGGCAGCCTT GCTGGTCACC 
ACGCGGCCCA GGGCACTGAG GGACCTCCAG CTCCTGGCGC AGCAGCCGAT CTACGTAAGG 
GTGGAGGGCT TCCTGGAGGA GGACAGGAGG GCCTATTTCC TGAGACACTT TGGAGACGAG 
GACCAAGCCA TGCGTGCCTT TGAGCTAATG AGGAGCAACG CGGCCCTGTT CCAGCTGGGC 
TCGGCCCCCG CGGTGTGCTG GATTGTGTGC ACGACTCTGA AGCTGCAGAT GGAGAAGGGG 
GAGGACCCGG TCCCCACCTG CCTCACCCGC ACGGGGCTGT TCCTGCGTTT CCTCTGCAGC 
CGGTTCCCGC AGGGCGCACA GCTGCGGGGC GCGCTGCGGA CGCTGAGCCT CCTGGCCGCG 
CAGGGCCTGT GGGCGCAGAT GTCCGTGTTC CACCGAGAGG ACCTGGAAAG GCTCGGGGTG 
CAGGAGTCCG ACCTCCGTCT GTTCCTGGAC GGAGACATCC TCCGCCAGGA CAGAGTCTCC 
AAAGGCTGCT ACTCCTTCAT CCACCTCAGC TTCCAGCAGT TTCTCACTGC CCTGTTCTAC 
GCCCTGGAGA AGGAGGAGGG GGAGGACAGG GACGGCCACG CCTGGGACAT CGGGGACGTA 
CAGAAGCTGC TTTCCGGAGA AGAAAGACTC AAGAACCCCG ACCTGATTCA AGTAGGACAC 
TTCTTATTCG GCCTCGCTAA CGAGAAGAGA GCCAAGGAGT TGGAGGCCAC TTTTGGCTGC 
CGGATGTCAC CGGACATCAA ACAGGAATTG CTGCAATGCA AAGCACATCT TCATGCAAAT 
AAGCCCTTAT CCGTGACCGA CCTGAAGGAG GTCTTGGGCT GCCTGTATGA GTCTCAGGAG 
GAGGAGCTGG CGAAGGTGGT GGTGGCCCCG TTCAAGGAAA TTTCTATTCA CCTGACAAAT 
ACTTCTGAAG TGATGCATTG TTCCTTCAGC CTGAAGCATT GTCAAGACTT GCAGAAACTC 
TCACTGCAGG TAGCAAAGGG GGTGTTCCTG GAGAATTACA TGGATTTTGA ACTGGACATT 
GAATTTGAAA GGTGCACTTA CCTAACCATT CCGAACTGGG CTCGGCAGGA TCTTCGCTCT 
CTTCGCCTCT GGACAGATTT CTGCTCTCTC TTCAGCTCAA ACAGCAACCT CAAGTTTCTG 
GAAGTGAAAC AAAGCTTCCT GAGTGACTCT TCTGTGCGGA TTCTTTGTGA CCACGTAACC 
CGTAGCACCT GTCATCTGCA GAAAGTGGAG ATTAAAAACG TCACCCCTGA CACCGCGTAC 
CGGGACTTCT GTCTTGCTTT CATTGGGAAG AAGACCCTCA CGCACCTGAC CCTGGCAGGG 
CACATCGAGT GGGAACGCAC GATGATGCTG ATGCTGTGTG ACCTGCTCAG AAATCATAAA 
TGCAACCTGC AGTACCTGAG GTTGGGAGGT CACTGTGCCA CCCCGGAGCA GTGGGCTGAA 
TTCTTCTATG TCCTCAAAGC CAACCAGTCC CTGAAGCACC TGCGTCTCTC AGCCAATGTG 
CTCCTGGATG AGGGTGCCAT GTTGCTGTAC AAGACCATGA CACGCCCAAA ACACTTCCTG 
CAGATGTTGT CGTTGGAAAA CTGTCGTCTT ACAGAAGCCA GTTGCAAGGA CCTTGCTGCT 
GTCTTGGTTG TCAGCAAGAA GCTGACACAC CTGTGCTTGG CCAAGAACCC CATTGGGGAT 
ACAGGGGTGA AGTTTCTGTG TGAGGGCTTG AGTTACCCTG ATTGTAAACT GCAGACCTTG 
GTGTTACAGC AATGCAGCAT AACCAAGCTT GGCTGTAGAT ATCTCTCAGA GGCGCTCCAA 
GAAGCCTGCA GCCTCACAAA CCTGGACTTG AGTATCAACC AGATAGCTCG TGGATTGTGG 
ATTCTCTGTC AGGCATTAGA GAATCCAAAC TGTAACCTAA AACACCTACG CCTCTGGAGC 
TGCTCCCTCA TGCCTTTCTA TTGTCAGCAT CTTGGATCTG CTCTCCTCAG CAATCAGAAG 
CTTGAAACTC TGGACCTGGG CCAGAATCAT TTGTGGAAGA GTGGCATAAT TAAGCTCTTT 
GGGGTTCTAA GACAAAGAAC TGGATCCTTG AAGATACTCA GGTTGAAGAC CTATGAAACT 
AATTTGGAAA TCAAGAAGCT GTTGGAGGAA GTGAAAGAAA AGAATCCCAA GCTGACTATT 
GATTGCAATG CTTCCGGGGC AACGGCACCT CCGTGCTGTG ACTTTTTTTG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP7 ( XM_011526599.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011524901.1 Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu18156
Clone ID Related Accession (Same CDS sequence)	XM_006723075.3 , NM_001127255.1 , XM_006723076.3 , XM_011526599.2
Accession Version	XM_011526599.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3114bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 7 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011526599.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACATCGC CCCAGCTAGA GTGGACTCTG CAGACCCTTC TGGAGCAGCT GAACGAGGAT 
GAATTAAAGA GTTTCAAATC CCTTTTATGG GCTTTTCCCC TCGAAGACGT GCTACAGAAG 
ACCCCATGGT CTGAGGTGGA AGAGGCTGAT GGCAAGAAAC TGGCAGAAAT TCTGGTCAAC 
ACCTCCTCAG AAAATTGGAT AAGGAATGCG ACTGTGAACA TCTTGGAAGA GATGAATCTC 
ACGGAATTGT GTAAGATGGC AAAGGCTGAG ATGATGGAGG ACGGACAGGT GCAAGAAATA 
GATAATCCTG AGCTGGGAGA TGCAGAAGAA GACTCGGAGT TAGCAAAGCC AGGTGAAAAG 
GAAGGATGGA GAAATTCAAT GGAGAAACAG TCTTTGGTCT GGAAGAACAC CTTTTGGCAA 
GGAGACATTG ACAATTTCCA TGACGACGTC ACTCTGAGAA ACCAACGGTT CATTCCATTC 
TTGAATCCCA GAACACCCAG GAAGCTAACA CCTTACACGG TGGTGCTGCA CGGCCCCGCA 
GGCGTGGGGA AAACCACGCT GGCCAAAAAG TGTATGCTGG ACTGGACAGA CTGCAACCTC 
AGCCCGACGC TCAGATACGC GTTCTACCTC AGCTGCAAGG AGCTCAGCCG CATGGGCCCC 
TGCAGTTTTG CAGAGCTGAT CTCCAAAGAC TGGCCTGAAT TGCAGGATGA CATTCCAAGC 
ATCCTAGCCC AAGCACAGAG AATCCTGTTC GTGGTCGATG GCCTTGATGA GCTGAAAGTC 
CCACCTGGGG CGCTGATCCA GGACATCTGC GGGGACTGGG AGAAGAAGAA GCCGGTGCCC 
GTCCTCCTGG GGAGTTTGCT GAAGAGGAAG ATGTTACCCA GGGCAGCCTT GCTGGTCACC 
ACGCGGCCCA GGGCACTGAG GGACCTCCAG CTCCTGGCGC AGCAGCCGAT CTACGTAAGG 
GTGGAGGGCT TCCTGGAGGA GGACAGGAGG GCCTATTTCC TGAGACACTT TGGAGACGAG 
GACCAAGCCA TGCGTGCCTT TGAGCTAATG AGGAGCAACG CGGCCCTGTT CCAGCTGGGC 
TCGGCCCCCG CGGTGTGCTG GATTGTGTGC ACGACTCTGA AGCTGCAGAT GGAGAAGGGG 
GAGGACCCGG TCCCCACCTG CCTCACCCGC ACGGGGCTGT TCCTGCGTTT CCTCTGCAGC 
CGGTTCCCGC AGGGCGCACA GCTGCGGGGC GCGCTGCGGA CGCTGAGCCT CCTGGCCGCG 
CAGGGCCTGT GGGCGCAGAT GTCCGTGTTC CACCGAGAGG ACCTGGAAAG GCTCGGGGTG 
CAGGAGTCCG ACCTCCGTCT GTTCCTGGAC GGAGACATCC TCCGCCAGGA CAGAGTCTCC 
AAAGGCTGCT ACTCCTTCAT CCACCTCAGC TTCCAGCAGT TTCTCACTGC CCTGTTCTAC 
GCCCTGGAGA AGGAGGAGGG GGAGGACAGG GACGGCCACG CCTGGGACAT CGGGGACGTA 
CAGAAGCTGC TTTCCGGAGA AGAAAGACTC AAGAACCCCG ACCTGATTCA AGTAGGACAC 
TTCTTATTCG GCCTCGCTAA CGAGAAGAGA GCCAAGGAGT TGGAGGCCAC TTTTGGCTGC 
CGGATGTCAC CGGACATCAA ACAGGAATTG CTGCAATGCA AAGCACATCT TCATGCAAAT 
AAGCCCTTAT CCGTGACCGA CCTGAAGGAG GTCTTGGGCT GCCTGTATGA GTCTCAGGAG 
GAGGAGCTGG CGAAGGTGGT GGTGGCCCCG TTCAAGGAAA TTTCTATTCA CCTGACAAAT 
ACTTCTGAAG TGATGCATTG TTCCTTCAGC CTGAAGCATT GTCAAGACTT GCAGAAACTC 
TCACTGCAGG TAGCAAAGGG GGTGTTCCTG GAGAATTACA TGGATTTTGA ACTGGACATT 
GAATTTGAAA GGTGCACTTA CCTAACCATT CCGAACTGGG CTCGGCAGGA TCTTCGCTCT 
CTTCGCCTCT GGACAGATTT CTGCTCTCTC TTCAGCTCAA ACAGCAACCT CAAGTTTCTG 
GAAGTGAAAC AAAGCTTCCT GAGTGACTCT TCTGTGCGGA TTCTTTGTGA CCACGTAACC 
CGTAGCACCT GTCATCTGCA GAAAGTGGAG ATTAAAAACG TCACCCCTGA CACCGCGTAC 
CGGGACTTCT GTCTTGCTTT CATTGGGAAG AAGACCCTCA CGCACCTGAC CCTGGCAGGG 
CACATCGAGT GGGAACGCAC GATGATGCTG ATGCTGTGTG ACCTGCTCAG AAATCATAAA 
TGCAACCTGC AGTACCTGAG GTTGGGAGGT CACTGTGCCA CCCCGGAGCA GTGGGCTGAA 
TTCTTCTATG TCCTCAAAGC CAACCAGTCC CTGAAGCACC TGCGTCTCTC AGCCAATGTG 
CTCCTGGATG AGGGTGCCAT GTTGCTGTAC AAGACCATGA CACGCCCAAA ACACTTCCTG 
CAGATGTTGT CGTTGGAAAA CTGTCGTCTT ACAGAAGCCA GTTGCAAGGA CCTTGCTGCT 
GTCTTGGTTG TCAGCAAGAA GCTGACACAC CTGTGCTTGG CCAAGAACCC CATTGGGGAT 
ACAGGGGTGA AGTTTCTGTG TGAGGGCTTG AGTTACCCTG ATTGTAAACT GCAGACCTTG 
GTGTTACAGC AATGCAGCAT AACCAAGCTT GGCTGTAGAT ATCTCTCAGA GGCGCTCCAA 
GAAGCCTGCA GCCTCACAAA CCTGGACTTG AGTATCAACC AGATAGCTCG TGGATTGTGG 
ATTCTCTGTC AGGCATTAGA GAATCCAAAC TGTAACCTAA AACACCTACG CCTCTGGAGC 
TGCTCCCTCA TGCCTTTCTA TTGTCAGCAT CTTGGATCTG CTCTCCTCAG CAATCAGAAG 
CTTGAAACTC TGGACCTGGG CCAGAATCAT TTGTGGAAGA GTGGCATAAT TAAGCTCTTT 
GGGGTTCTAA GACAAAGAAC TGGATCCTTG AAGATACTCA GGTTGAAGAC CTATGAAACT 
AATTTGGAAA TCAAGAAGCT GTTGGAGGAA GTGAAAGAAA AGAATCCCAA GCTGACTATT 
GATTGCAATG CTTCCGGGGC AACGGCACCT CCGTGCTGTG ACTTTTTTTG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011524901.1
CDS	530..3643
Translation	MTSPQLEWTLQTLLEQLNEDELKSFKSLLWAFPLEDVLQKTPWSEVEEADGKKLAEILVNTSSENWIRNATVNILEEMNLTELCKMAKAEMMEDGQVQEIDNPELGDAEEDSELAKPGEKEGWRNSMEKQSLVWKNTFWQGDIDNFHDDVTLRNQRFIPFLNPRTPRKLTPYTVVLHGPAGVGKTTLAKKCMLDWTDCNLSPTLRYAFYLSCKELSRMGPCSFAELISKDWPELQDDIPSILAQAQRILFVVDGLDELKVPPGALIQDICGDWEKKKPVPVLLGSLLKRKMLPRAALLVTTRPRALRDLQLLAQQPIYVRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQGAQLRGALRTLSLLAAQGLWAQMSVFHREDLERLGVQESDLRLFLDGDILRQDRVSKGCYSFIHLSFQQFLTALFYALEKEEGEDRDGHAWDIGDVQKLLSGEERLKNPDLIQVGHFLFGLANEKRAKELEATFGCRMSPDIKQELLQCKAHLHANKPLSVTDLKEVLGCLYESQEEELAKVVVAPFKEISIHLTNTSEVMHCSFSLKHCQDLQKLSLQVAKGVFLENYMDFELDIEFERCTYLTIPNWARQDLRSLRLWTDFCSLFSSNSNLKFLEVKQSFLSDSSVRILCDHVTRSTCHLQKVEIKNVTPDTAYRDFCLAFIGKKTLTHLTLAGHIEWERTMMLMLCDLLRNHKCNLQYLRLGGHCATPEQWAEFFYVLKANQSLKHLRLSANVLLDEGAMLLYKTMTRPKHFLQMLSLENCRLTEASCKDLAAVLVVSKKLTHLCLAKNPIGDTGVKFLCEGLSYPDCKLQTLVLQQCSITKLGCRYLSEALQEACSLTNLDLSINQIARGLWILCQALENPNCNLKHLRLWSCSLMPFYCQHLGSALLSNQKLETLDLGQNHLWKSGIIKLFGVLRQRTGSLKILRLKTYETNLEIKKLLEEVKEKNPKLTIDCNASGATAPPCCDFFC

Target ORF information:

RefSeq Version	XM_011526599.2
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011526599.2

ORF Insert Sequence:

ATGACATCGC CCCAGCTAGA GTGGACTCTG CAGACCCTTC TGGAGCAGCT GAACGAGGAT 
GAATTAAAGA GTTTCAAATC CCTTTTATGG GCTTTTCCCC TCGAAGACGT GCTACAGAAG 
ACCCCATGGT CTGAGGTGGA AGAGGCTGAT GGCAAGAAAC TGGCAGAAAT TCTGGTCAAC 
ACCTCCTCAG AAAATTGGAT AAGGAATGCG ACTGTGAACA TCTTGGAAGA GATGAATCTC 
ACGGAATTGT GTAAGATGGC AAAGGCTGAG ATGATGGAGG ACGGACAGGT GCAAGAAATA 
GATAATCCTG AGCTGGGAGA TGCAGAAGAA GACTCGGAGT TAGCAAAGCC AGGTGAAAAG 
GAAGGATGGA GAAATTCAAT GGAGAAACAG TCTTTGGTCT GGAAGAACAC CTTTTGGCAA 
GGAGACATTG ACAATTTCCA TGACGACGTC ACTCTGAGAA ACCAACGGTT CATTCCATTC 
TTGAATCCCA GAACACCCAG GAAGCTAACA CCTTACACGG TGGTGCTGCA CGGCCCCGCA 
GGCGTGGGGA AAACCACGCT GGCCAAAAAG TGTATGCTGG ACTGGACAGA CTGCAACCTC 
AGCCCGACGC TCAGATACGC GTTCTACCTC AGCTGCAAGG AGCTCAGCCG CATGGGCCCC 
TGCAGTTTTG CAGAGCTGAT CTCCAAAGAC TGGCCTGAAT TGCAGGATGA CATTCCAAGC 
ATCCTAGCCC AAGCACAGAG AATCCTGTTC GTGGTCGATG GCCTTGATGA GCTGAAAGTC 
CCACCTGGGG CGCTGATCCA GGACATCTGC GGGGACTGGG AGAAGAAGAA GCCGGTGCCC 
GTCCTCCTGG GGAGTTTGCT GAAGAGGAAG ATGTTACCCA GGGCAGCCTT GCTGGTCACC 
ACGCGGCCCA GGGCACTGAG GGACCTCCAG CTCCTGGCGC AGCAGCCGAT CTACGTAAGG 
GTGGAGGGCT TCCTGGAGGA GGACAGGAGG GCCTATTTCC TGAGACACTT TGGAGACGAG 
GACCAAGCCA TGCGTGCCTT TGAGCTAATG AGGAGCAACG CGGCCCTGTT CCAGCTGGGC 
TCGGCCCCCG CGGTGTGCTG GATTGTGTGC ACGACTCTGA AGCTGCAGAT GGAGAAGGGG 
GAGGACCCGG TCCCCACCTG CCTCACCCGC ACGGGGCTGT TCCTGCGTTT CCTCTGCAGC 
CGGTTCCCGC AGGGCGCACA GCTGCGGGGC GCGCTGCGGA CGCTGAGCCT CCTGGCCGCG 
CAGGGCCTGT GGGCGCAGAT GTCCGTGTTC CACCGAGAGG ACCTGGAAAG GCTCGGGGTG 
CAGGAGTCCG ACCTCCGTCT GTTCCTGGAC GGAGACATCC TCCGCCAGGA CAGAGTCTCC 
AAAGGCTGCT ACTCCTTCAT CCACCTCAGC TTCCAGCAGT TTCTCACTGC CCTGTTCTAC 
GCCCTGGAGA AGGAGGAGGG GGAGGACAGG GACGGCCACG CCTGGGACAT CGGGGACGTA 
CAGAAGCTGC TTTCCGGAGA AGAAAGACTC AAGAACCCCG ACCTGATTCA AGTAGGACAC 
TTCTTATTCG GCCTCGCTAA CGAGAAGAGA GCCAAGGAGT TGGAGGCCAC TTTTGGCTGC 
CGGATGTCAC CGGACATCAA ACAGGAATTG CTGCAATGCA AAGCACATCT TCATGCAAAT 
AAGCCCTTAT CCGTGACCGA CCTGAAGGAG GTCTTGGGCT GCCTGTATGA GTCTCAGGAG 
GAGGAGCTGG CGAAGGTGGT GGTGGCCCCG TTCAAGGAAA TTTCTATTCA CCTGACAAAT 
ACTTCTGAAG TGATGCATTG TTCCTTCAGC CTGAAGCATT GTCAAGACTT GCAGAAACTC 
TCACTGCAGG TAGCAAAGGG GGTGTTCCTG GAGAATTACA TGGATTTTGA ACTGGACATT 
GAATTTGAAA GGTGCACTTA CCTAACCATT CCGAACTGGG CTCGGCAGGA TCTTCGCTCT 
CTTCGCCTCT GGACAGATTT CTGCTCTCTC TTCAGCTCAA ACAGCAACCT CAAGTTTCTG 
GAAGTGAAAC AAAGCTTCCT GAGTGACTCT TCTGTGCGGA TTCTTTGTGA CCACGTAACC 
CGTAGCACCT GTCATCTGCA GAAAGTGGAG ATTAAAAACG TCACCCCTGA CACCGCGTAC 
CGGGACTTCT GTCTTGCTTT CATTGGGAAG AAGACCCTCA CGCACCTGAC CCTGGCAGGG 
CACATCGAGT GGGAACGCAC GATGATGCTG ATGCTGTGTG ACCTGCTCAG AAATCATAAA 
TGCAACCTGC AGTACCTGAG GTTGGGAGGT CACTGTGCCA CCCCGGAGCA GTGGGCTGAA 
TTCTTCTATG TCCTCAAAGC CAACCAGTCC CTGAAGCACC TGCGTCTCTC AGCCAATGTG 
CTCCTGGATG AGGGTGCCAT GTTGCTGTAC AAGACCATGA CACGCCCAAA ACACTTCCTG 
CAGATGTTGT CGTTGGAAAA CTGTCGTCTT ACAGAAGCCA GTTGCAAGGA CCTTGCTGCT 
GTCTTGGTTG TCAGCAAGAA GCTGACACAC CTGTGCTTGG CCAAGAACCC CATTGGGGAT 
ACAGGGGTGA AGTTTCTGTG TGAGGGCTTG AGTTACCCTG ATTGTAAACT GCAGACCTTG 
GTGTTACAGC AATGCAGCAT AACCAAGCTT GGCTGTAGAT ATCTCTCAGA GGCGCTCCAA 
GAAGCCTGCA GCCTCACAAA CCTGGACTTG AGTATCAACC AGATAGCTCG TGGATTGTGG 
ATTCTCTGTC AGGCATTAGA GAATCCAAAC TGTAACCTAA AACACCTACG CCTCTGGAGC 
TGCTCCCTCA TGCCTTTCTA TTGTCAGCAT CTTGGATCTG CTCTCCTCAG CAATCAGAAG 
CTTGAAACTC TGGACCTGGG CCAGAATCAT TTGTGGAAGA GTGGCATAAT TAAGCTCTTT 
GGGGTTCTAA GACAAAGAAC TGGATCCTTG AAGATACTCA GGTTGAAGAC CTATGAAACT 
AATTTGGAAA TCAAGAAGCT GTTGGAGGAA GTGAAAGAAA AGAATCCCAA GCTGACTATT 
GATTGCAATG CTTCCGGGGC AACGGCACCT CCGTGCTGTG ACTTTTTTTG CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP7 ( XM_011526596.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011524898.1 Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu77568
Clone ID Related Accession (Same CDS sequence)	XM_011526596.2
Accession Version	XM_011526596.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3198bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 7 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011526596.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAAGGA AACACAGGCT GGAAGCAAGA CCTGACCTGA GGGAGTTCTT CAGCCTTAAC 
CTAAGGTCTC ATACTCGGAG CACTATGACA TCGCCCCAGC TAGAGTGGAC TCTGCAGACC 
CTTCTGGAGC AGCTGAACGA GGATGAATTA AAGAGTTTCA AATCCCTTTT ATGGGCTTTT 
CCCCTCGAAG ACGTGCTACA GAAGACCCCA TGGTCTGAGG TGGAAGAGGC TGATGGCAAG 
AAACTGGCAG AAATTCTGGT CAACACCTCC TCAGAAAATT GGATAAGGAA TGCGACTGTG 
AACATCTTGG AAGAGATGAA TCTCACGGAA TTGTGTAAGA TGGCAAAGGC TGAGATGATG 
GAGGACGGAC AGGTGCAAGA AATAGATAAT CCTGAGCTGG GAGATGCAGA AGAAGACTCG 
GAGTTAGCAA AGCCAGGTGA AAAGGAAGGA TGGAGAAATT CAATGGAGAA ACAGTCTTTG 
GTCTGGAAGA ACACCTTTTG GCAAGGAGAC ATTGACAATT TCCATGACGA CGTCACTCTG 
AGAAACCAAC GGTTCATTCC ATTCTTGAAT CCCAGAACAC CCAGGAAGCT AACACCTTAC 
ACGGTGGTGC TGCACGGCCC CGCAGGCGTG GGGAAAACCA CGCTGGCCAA AAAGTGTATG 
CTGGACTGGA CAGACTGCAA CCTCAGCCCG ACGCTCAGAT ACGCGTTCTA CCTCAGCTGC 
AAGGAGCTCA GCCGCATGGG CCCCTGCAGT TTTGCAGAGC TGATCTCCAA AGACTGGCCT 
GAATTGCAGG ATGACATTCC AAGCATCCTA GCCCAAGCAC AGAGAATCCT GTTCGTGGTC 
GATGGCCTTG ATGAGCTGAA AGTCCCACCT GGGGCGCTGA TCCAGGACAT CTGCGGGGAC 
TGGGAGAAGA AGAAGCCGGT GCCCGTCCTC CTGGGGAGTT TGCTGAAGAG GAAGATGTTA 
CCCAGGGCAG CCTTGCTGGT CACCACGCGG CCCAGGGCAC TGAGGGACCT CCAGCTCCTG 
GCGCAGCAGC CGATCTACGT AAGGGTGGAG GGCTTCCTGG AGGAGGACAG GAGGGCCTAT 
TTCCTGAGAC ACTTTGGAGA CGAGGACCAA GCCATGCGTG CCTTTGAGCT AATGAGGAGC 
AACGCGGCCC TGTTCCAGCT GGGCTCGGCC CCCGCGGTGT GCTGGATTGT GTGCACGACT 
CTGAAGCTGC AGATGGAGAA GGGGGAGGAC CCGGTCCCCA CCTGCCTCAC CCGCACGGGG 
CTGTTCCTGC GTTTCCTCTG CAGCCGGTTC CCGCAGGGCG CACAGCTGCG GGGCGCGCTG 
CGGACGCTGA GCCTCCTGGC CGCGCAGGGC CTGTGGGCGC AGATGTCCGT GTTCCACCGA 
GAGGACCTGG AAAGGCTCGG GGTGCAGGAG TCCGACCTCC GTCTGTTCCT GGACGGAGAC 
ATCCTCCGCC AGGACAGAGT CTCCAAAGGC TGCTACTCCT TCATCCACCT CAGCTTCCAG 
CAGTTTCTCA CTGCCCTGTT CTACGCCCTG GAGAAGGAGG AGGGGGAGGA CAGGGACGGC 
CACGCCTGGG ACATCGGGGA CGTACAGAAG CTGCTTTCCG GAGAAGAAAG ACTCAAGAAC 
CCCGACCTGA TTCAAGTAGG ACACTTCTTA TTCGGCCTCG CTAACGAGAA GAGAGCCAAG 
GAGTTGGAGG CCACTTTTGG CTGCCGGATG TCACCGGACA TCAAACAGGA ATTGCTGCAA 
TGCAAAGCAC ATCTTCATGC AAATAAGCCC TTATCCGTGA CCGACCTGAA GGAGGTCTTG 
GGCTGCCTGT ATGAGTCTCA GGAGGAGGAG CTGGCGAAGG TGGTGGTGGC CCCGTTCAAG 
GAAATTTCTA TTCACCTGAC AAATACTTCT GAAGTGATGC ATTGTTCCTT CAGCCTGAAG 
CATTGTCAAG ACTTGCAGAA ACTCTCACTG CAGGTAGCAA AGGGGGTGTT CCTGGAGAAT 
TACATGGATT TTGAACTGGA CATTGAATTT GAAAGGTGCA CTTACCTAAC CATTCCGAAC 
TGGGCTCGGC AGGATCTTCG CTCTCTTCGC CTCTGGACAG ATTTCTGCTC TCTCTTCAGC 
TCAAACAGCA ACCTCAAGTT TCTGGAAGTG AAACAAAGCT TCCTGAGTGA CTCTTCTGTG 
CGGATTCTTT GTGACCACGT AACCCGTAGC ACCTGTCATC TGCAGAAAGT GGAGATTAAA 
AACGTCACCC CTGACACCGC GTACCGGGAC TTCTGTCTTG CTTTCATTGG GAAGAAGACC 
CTCACGCACC TGACCCTGGC AGGGCACATC GAGTGGGAAC GCACGATGAT GCTGATGCTG 
TGTGACCTGC TCAGAAATCA TAAATGCAAC CTGCAGTACC TGAGGTTGGG AGGTCACTGT 
GCCACCCCGG AGCAGTGGGC TGAATTCTTC TATGTCCTCA AAGCCAACCA GTCCCTGAAG 
CACCTGCGTC TCTCAGCCAA TGTGCTCCTG GATGAGGGTG CCATGTTGCT GTACAAGACC 
ATGACACGCC CAAAACACTT CCTGCAGATG TTGTCGTTGG AAAACTGTCG TCTTACAGAA 
GCCAGTTGCA AGGACCTTGC TGCTGTCTTG GTTGTCAGCA AGAAGCTGAC ACACCTGTGC 
TTGGCCAAGA ACCCCATTGG GGATACAGGG GTGAAGTTTC TGTGTGAGGG CTTGAGTTAC 
CCTGATTGTA AACTGCAGAC CTTGGTGTTA CAGCAATGCA GCATAACCAA GCTTGGCTGT 
AGATATCTCT CAGAGGCGCT CCAAGAAGCC TGCAGCCTCA CAAACCTGGA CTTGAGTATC 
AACCAGATAG CTCGTGGATT GTGGATTCTC TGTCAGGCAT TAGAGAATCC AAACTGTAAC 
CTAAAACACC TACGCCTCTG GAGCTGCTCC CTCATGCCTT TCTATTGTCA GCATCTTGGA 
TCTGCTCTCC TCAGCAATCA GAAGCTTGAA ACTCTGGACC TGGGCCAGAA TCATTTGTGG 
AAGAGTGGCA TAATTAAGCT CTTTGGGGTT CTAAGACAAA GAACTGGATC CTTGAAGATA 
CTCAGGTTGA AGACCTATGA AACTAATTTG GAAATCAAGA AGCTGTTGGA GGAAGTGAAA 
GAAAAGAATC CCAAGCTGAC TATTGATTGC AATGCTTCCG GGGCAACGGC ACCTCCGTGC 
TGTGACTTTT TTTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011524898.1
CDS	435..3632
Translation	MSRKHRLEARPDLREFFSLNLRSHTRSTMTSPQLEWTLQTLLEQLNEDELKSFKSLLWAFPLEDVLQKTPWSEVEEADGKKLAEILVNTSSENWIRNATVNILEEMNLTELCKMAKAEMMEDGQVQEIDNPELGDAEEDSELAKPGEKEGWRNSMEKQSLVWKNTFWQGDIDNFHDDVTLRNQRFIPFLNPRTPRKLTPYTVVLHGPAGVGKTTLAKKCMLDWTDCNLSPTLRYAFYLSCKELSRMGPCSFAELISKDWPELQDDIPSILAQAQRILFVVDGLDELKVPPGALIQDICGDWEKKKPVPVLLGSLLKRKMLPRAALLVTTRPRALRDLQLLAQQPIYVRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQGAQLRGALRTLSLLAAQGLWAQMSVFHREDLERLGVQESDLRLFLDGDILRQDRVSKGCYSFIHLSFQQFLTALFYALEKEEGEDRDGHAWDIGDVQKLLSGEERLKNPDLIQVGHFLFGLANEKRAKELEATFGCRMSPDIKQELLQCKAHLHANKPLSVTDLKEVLGCLYESQEEELAKVVVAPFKEISIHLTNTSEVMHCSFSLKHCQDLQKLSLQVAKGVFLENYMDFELDIEFERCTYLTIPNWARQDLRSLRLWTDFCSLFSSNSNLKFLEVKQSFLSDSSVRILCDHVTRSTCHLQKVEIKNVTPDTAYRDFCLAFIGKKTLTHLTLAGHIEWERTMMLMLCDLLRNHKCNLQYLRLGGHCATPEQWAEFFYVLKANQSLKHLRLSANVLLDEGAMLLYKTMTRPKHFLQMLSLENCRLTEASCKDLAAVLVVSKKLTHLCLAKNPIGDTGVKFLCEGLSYPDCKLQTLVLQQCSITKLGCRYLSEALQEACSLTNLDLSINQIARGLWILCQALENPNCNLKHLRLWSCSLMPFYCQHLGSALLSNQKLETLDLGQNHLWKSGIIKLFGVLRQRTGSLKILRLKTYETNLEIKKLLEEVKEKNPKLTIDCNASGATAPPCCDFFC

Target ORF information:

RefSeq Version	XM_011526596.2
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011526596.2

ORF Insert Sequence:

ATGTCAAGGA AACACAGGCT GGAAGCAAGA CCTGACCTGA GGGAGTTCTT CAGCCTTAAC 
CTAAGGTCTC ATACTCGGAG CACTATGACA TCGCCCCAGC TAGAGTGGAC TCTGCAGACC 
CTTCTGGAGC AGCTGAACGA GGATGAATTA AAGAGTTTCA AATCCCTTTT ATGGGCTTTT 
CCCCTCGAAG ACGTGCTACA GAAGACCCCA TGGTCTGAGG TGGAAGAGGC TGATGGCAAG 
AAACTGGCAG AAATTCTGGT CAACACCTCC TCAGAAAATT GGATAAGGAA TGCGACTGTG 
AACATCTTGG AAGAGATGAA TCTCACGGAA TTGTGTAAGA TGGCAAAGGC TGAGATGATG 
GAGGACGGAC AGGTGCAAGA AATAGATAAT CCTGAGCTGG GAGATGCAGA AGAAGACTCG 
GAGTTAGCAA AGCCAGGTGA AAAGGAAGGA TGGAGAAATT CAATGGAGAA ACAGTCTTTG 
GTCTGGAAGA ACACCTTTTG GCAAGGAGAC ATTGACAATT TCCATGACGA CGTCACTCTG 
AGAAACCAAC GGTTCATTCC ATTCTTGAAT CCCAGAACAC CCAGGAAGCT AACACCTTAC 
ACGGTGGTGC TGCACGGCCC CGCAGGCGTG GGGAAAACCA CGCTGGCCAA AAAGTGTATG 
CTGGACTGGA CAGACTGCAA CCTCAGCCCG ACGCTCAGAT ACGCGTTCTA CCTCAGCTGC 
AAGGAGCTCA GCCGCATGGG CCCCTGCAGT TTTGCAGAGC TGATCTCCAA AGACTGGCCT 
GAATTGCAGG ATGACATTCC AAGCATCCTA GCCCAAGCAC AGAGAATCCT GTTCGTGGTC 
GATGGCCTTG ATGAGCTGAA AGTCCCACCT GGGGCGCTGA TCCAGGACAT CTGCGGGGAC 
TGGGAGAAGA AGAAGCCGGT GCCCGTCCTC CTGGGGAGTT TGCTGAAGAG GAAGATGTTA 
CCCAGGGCAG CCTTGCTGGT CACCACGCGG CCCAGGGCAC TGAGGGACCT CCAGCTCCTG 
GCGCAGCAGC CGATCTACGT AAGGGTGGAG GGCTTCCTGG AGGAGGACAG GAGGGCCTAT 
TTCCTGAGAC ACTTTGGAGA CGAGGACCAA GCCATGCGTG CCTTTGAGCT AATGAGGAGC 
AACGCGGCCC TGTTCCAGCT GGGCTCGGCC CCCGCGGTGT GCTGGATTGT GTGCACGACT 
CTGAAGCTGC AGATGGAGAA GGGGGAGGAC CCGGTCCCCA CCTGCCTCAC CCGCACGGGG 
CTGTTCCTGC GTTTCCTCTG CAGCCGGTTC CCGCAGGGCG CACAGCTGCG GGGCGCGCTG 
CGGACGCTGA GCCTCCTGGC CGCGCAGGGC CTGTGGGCGC AGATGTCCGT GTTCCACCGA 
GAGGACCTGG AAAGGCTCGG GGTGCAGGAG TCCGACCTCC GTCTGTTCCT GGACGGAGAC 
ATCCTCCGCC AGGACAGAGT CTCCAAAGGC TGCTACTCCT TCATCCACCT CAGCTTCCAG 
CAGTTTCTCA CTGCCCTGTT CTACGCCCTG GAGAAGGAGG AGGGGGAGGA CAGGGACGGC 
CACGCCTGGG ACATCGGGGA CGTACAGAAG CTGCTTTCCG GAGAAGAAAG ACTCAAGAAC 
CCCGACCTGA TTCAAGTAGG ACACTTCTTA TTCGGCCTCG CTAACGAGAA GAGAGCCAAG 
GAGTTGGAGG CCACTTTTGG CTGCCGGATG TCACCGGACA TCAAACAGGA ATTGCTGCAA 
TGCAAAGCAC ATCTTCATGC AAATAAGCCC TTATCCGTGA CCGACCTGAA GGAGGTCTTG 
GGCTGCCTGT ATGAGTCTCA GGAGGAGGAG CTGGCGAAGG TGGTGGTGGC CCCGTTCAAG 
GAAATTTCTA TTCACCTGAC AAATACTTCT GAAGTGATGC ATTGTTCCTT CAGCCTGAAG 
CATTGTCAAG ACTTGCAGAA ACTCTCACTG CAGGTAGCAA AGGGGGTGTT CCTGGAGAAT 
TACATGGATT TTGAACTGGA CATTGAATTT GAAAGGTGCA CTTACCTAAC CATTCCGAAC 
TGGGCTCGGC AGGATCTTCG CTCTCTTCGC CTCTGGACAG ATTTCTGCTC TCTCTTCAGC 
TCAAACAGCA ACCTCAAGTT TCTGGAAGTG AAACAAAGCT TCCTGAGTGA CTCTTCTGTG 
CGGATTCTTT GTGACCACGT AACCCGTAGC ACCTGTCATC TGCAGAAAGT GGAGATTAAA 
AACGTCACCC CTGACACCGC GTACCGGGAC TTCTGTCTTG CTTTCATTGG GAAGAAGACC 
CTCACGCACC TGACCCTGGC AGGGCACATC GAGTGGGAAC GCACGATGAT GCTGATGCTG 
TGTGACCTGC TCAGAAATCA TAAATGCAAC CTGCAGTACC TGAGGTTGGG AGGTCACTGT 
GCCACCCCGG AGCAGTGGGC TGAATTCTTC TATGTCCTCA AAGCCAACCA GTCCCTGAAG 
CACCTGCGTC TCTCAGCCAA TGTGCTCCTG GATGAGGGTG CCATGTTGCT GTACAAGACC 
ATGACACGCC CAAAACACTT CCTGCAGATG TTGTCGTTGG AAAACTGTCG TCTTACAGAA 
GCCAGTTGCA AGGACCTTGC TGCTGTCTTG GTTGTCAGCA AGAAGCTGAC ACACCTGTGC 
TTGGCCAAGA ACCCCATTGG GGATACAGGG GTGAAGTTTC TGTGTGAGGG CTTGAGTTAC 
CCTGATTGTA AACTGCAGAC CTTGGTGTTA CAGCAATGCA GCATAACCAA GCTTGGCTGT 
AGATATCTCT CAGAGGCGCT CCAAGAAGCC TGCAGCCTCA CAAACCTGGA CTTGAGTATC 
AACCAGATAG CTCGTGGATT GTGGATTCTC TGTCAGGCAT TAGAGAATCC AAACTGTAAC 
CTAAAACACC TACGCCTCTG GAGCTGCTCC CTCATGCCTT TCTATTGTCA GCATCTTGGA 
TCTGCTCTCC TCAGCAATCA GAAGCTTGAA ACTCTGGACC TGGGCCAGAA TCATTTGTGG 
AAGAGTGGCA TAATTAAGCT CTTTGGGGTT CTAAGACAAA GAACTGGATC CTTGAAGATA 
CTCAGGTTGA AGACCTATGA AACTAATTTG GAAATCAAGA AGCTGTTGGA GGAAGTGAAA 
GAAAAGAATC CCAAGCTGAC TATTGATTGC AATGCTTCCG GGGCAACGGC ACCTCCGTGC 
TGTGACTTTT TTTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NLRP7 ( XM_011526601.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011524903.1 Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant X5, mRNA.

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CloneID	OHu77569
Clone ID Related Accession (Same CDS sequence)	XM_011526601.2
Accession Version	XM_011526601.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3027bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	NACHT, LRR and PYD domains-containing protein 7 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011526601.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAAGGA AACACAGGCT GGAAGCAAGA CCTGACCTGA GGGAGTTCTT CAGCCTTAAC 
CTAAGGTCTC ATACTCGGAG CACTATGACA TCGCCCCAGC TAGAGTGGAC TCTGCAGACC 
CTTCTGGAGC AGCTGAACGA GGATGAATTA AAGAGTTTCA AATCCCTTTT ATGGGCTTTT 
CCCCTCGAAG ACGTGCTACA GAAGACCCCA TGGTCTGAGG TGGAAGAGGC TGATGGCAAG 
AAACTGGCAG AAATTCTGGT CAACACCTCC TCAGAAAATT GGATAAGGAA TGCGACTGTG 
AACATCTTGG AAGAGATGAA TCTCACGGAA TTGTGTAAGA TGGCAAAGGC TGAGATGATG 
GAGGACGGAC AGGTGCAAGA AATAGATAAT CCTGAGCTGG GAGATGCAGA AGAAGACTCG 
GAGTTAGCAA AGCCAGGTGA AAAGGAAGGA TGGAGAAATT CAATGGAGAA ACAGTCTTTG 
GTCTGGAAGA ACACCTTTTG GCAAGGAGAC ATTGACAATT TCCATGACGA CGTCACTCTG 
AGAAACCAAC GGTTCATTCC ATTCTTGAAT CCCAGAACAC CCAGGAAGCT AACACCTTAC 
ACGGTGGTGC TGCACGGCCC CGCAGGCGTG GGGAAAACCA CGCTGGCCAA AAAGTGTATG 
CTGGACTGGA CAGACTGCAA CCTCAGCCCG ACGCTCAGAT ACGCGTTCTA CCTCAGCTGC 
AAGGAGCTCA GCCGCATGGG CCCCTGCAGT TTTGCAGAGC TGATCTCCAA AGACTGGCCT 
GAATTGCAGG ATGACATTCC AAGCATCCTA GCCCAAGCAC AGAGAATCCT GTTCGTGGTC 
GATGGCCTTG ATGAGCTGAA AGTCCCACCT GGGGCGCTGA TCCAGGACAT CTGCGGGGAC 
TGGGAGAAGA AGAAGCCGGT GCCCGTCCTC CTGGGGAGTT TGCTGAAGAG GAAGATGTTA 
CCCAGGGCAG CCTTGCTGGT CACCACGCGG CCCAGGGCAC TGAGGGACCT CCAGCTCCTG 
GCGCAGCAGC CGATCTACGT AAGGGTGGAG GGCTTCCTGG AGGAGGACAG GAGGGCCTAT 
TTCCTGAGAC ACTTTGGAGA CGAGGACCAA GCCATGCGTG CCTTTGAGCT AATGAGGAGC 
AACGCGGCCC TGTTCCAGCT GGGCTCGGCC CCCGCGGTGT GCTGGATTGT GTGCACGACT 
CTGAAGCTGC AGATGGAGAA GGGGGAGGAC CCGGTCCCCA CCTGCCTCAC CCGCACGGGG 
CTGTTCCTGC GTTTCCTCTG CAGCCGGTTC CCGCAGGGCG CACAGCTGCG GGGCGCGCTG 
CGGACGCTGA GCCTCCTGGC CGCGCAGGGC CTGTGGGCGC AGATGTCCGT GTTCCACCGA 
GAGGACCTGG AAAGGCTCGG GGTGCAGGAG TCCGACCTCC GTCTGTTCCT GGACGGAGAC 
ATCCTCCGCC AGGACAGAGT CTCCAAAGGC TGCTACTCCT TCATCCACCT CAGCTTCCAG 
CAGTTTCTCA CTGCCCTGTT CTACGCCCTG GAGAAGGAGG AGGGGGAGGA CAGGGACGGC 
CACGCCTGGG ACATCGGGGA CGTACAGAAG CTGCTTTCCG GAGAAGAAAG ACTCAAGAAC 
CCCGACCTGA TTCAAGTAGG ACACTTCTTA TTCGGCCTCG CTAACGAGAA GAGAGCCAAG 
GAGTTGGAGG CCACTTTTGG CTGCCGGATG TCACCGGACA TCAAACAGGA ATTGCTGCAA 
TGCAAAGCAC ATCTTCATGC AAATAAGCCC TTATCCGTGA CCGACCTGAA GGAGGTCTTG 
GGCTGCCTGT ATGAGTCTCA GGAGGAGGAG CTGGCGAAGG TGGTGGTGGC CCCGTTCAAG 
GAAATTTCTA TTCACCTGAC AAATACTTCT GAAGTGATGC ATTGTTCCTT CAGCCTGAAG 
CATTGTCAAG ACTTGCAGAA ACTCTCACTG CAGGTAGCAA AGGGGGTGTT CCTGGAGAAT 
TACATGGATT TTGAACTGGA CATTGAATTT GAAAGGTGCA CTTACCTAAC CATTCCGAAC 
TGGGCTCGGC AGGATCTTCG CTCTCTTCGC CTCTGGACAG ATTTCTGCTC TCTCTTCAGC 
TCAAACAGCA ACCTCAAGTT TCTGGAAGTG AAACAAAGCT TCCTGAGTGA CTCTTCTGTG 
CGGATTCTTT GTGACCACGT AACCCGTAGC ACCTGTCATC TGCAGAAAGT GGAGATTAAA 
AACGTCACCC CTGACACCGC GTACCGGGAC TTCTGTCTTG CTTTCATTGG GAAGAAGACC 
CTCACGCACC TGACCCTGGC AGGGCACATC GAGTGGGAAC GCACGATGAT GCTGATGCTG 
TGTGACCTGC TCAGAAATCA TAAATGCAAC CTGCAGTACC TGAGGTTGGG AGGTCACTGT 
GCCACCCCGG AGCAGTGGGC TGAATTCTTC TATGTCCTCA AAGCCAACCA GTCCCTGAAG 
CACCTGCGTC TCTCAGCCAA TGTGCTCCTG GATGAGGGTG CCATGTTGCT GTACAAGACC 
ATGACACGCC CAAAACACTT CCTGCAGATG TTGTCGTTGG AAAACTGTCG TCTTACAGAA 
GCCAGTTGCA AGGACCTTGC TGCTGTCTTG GTTGTCAGCA AGAAGCTGAC ACACCTGTGC 
TTGGCCAAGA ACCCCATTGG GGATACAGGG GTGAAGTTTC TGTGTGAGGG CTTGAGTTAC 
CCTGATTGTA AACTGCAGAC CTTGGTGTTA CAGCAATGCA GCATAACCAA GCTTGGCTGT 
AGATATCTCT CAGAGGCGCT CCAAGAAGCC TGCAGCCTCA CAAACCTGGA CTTGAGTATC 
AACCAGATAG CTCGTGGATT GTGGATTCTC TGTCAGGCAT TAGAGAATCC AAACTGTAAC 
CTAAAACACC TACGGTTGAA GACCTATGAA ACTAATTTGG AAATCAAGAA GCTGTTGGAG 
GAAGTGAAAG AAAAGAATCC CAAGCTGACT ATTGATTGCA ATGCTTCCGG GGCAACGGCA 
CCTCCGTGCT GTGACTTTTT TTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011524903.1
CDS	435..3461
Translation	MSRKHRLEARPDLREFFSLNLRSHTRSTMTSPQLEWTLQTLLEQLNEDELKSFKSLLWAFPLEDVLQKTPWSEVEEADGKKLAEILVNTSSENWIRNATVNILEEMNLTELCKMAKAEMMEDGQVQEIDNPELGDAEEDSELAKPGEKEGWRNSMEKQSLVWKNTFWQGDIDNFHDDVTLRNQRFIPFLNPRTPRKLTPYTVVLHGPAGVGKTTLAKKCMLDWTDCNLSPTLRYAFYLSCKELSRMGPCSFAELISKDWPELQDDIPSILAQAQRILFVVDGLDELKVPPGALIQDICGDWEKKKPVPVLLGSLLKRKMLPRAALLVTTRPRALRDLQLLAQQPIYVRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQGAQLRGALRTLSLLAAQGLWAQMSVFHREDLERLGVQESDLRLFLDGDILRQDRVSKGCYSFIHLSFQQFLTALFYALEKEEGEDRDGHAWDIGDVQKLLSGEERLKNPDLIQVGHFLFGLANEKRAKELEATFGCRMSPDIKQELLQCKAHLHANKPLSVTDLKEVLGCLYESQEEELAKVVVAPFKEISIHLTNTSEVMHCSFSLKHCQDLQKLSLQVAKGVFLENYMDFELDIEFERCTYLTIPNWARQDLRSLRLWTDFCSLFSSNSNLKFLEVKQSFLSDSSVRILCDHVTRSTCHLQKVEIKNVTPDTAYRDFCLAFIGKKTLTHLTLAGHIEWERTMMLMLCDLLRNHKCNLQYLRLGGHCATPEQWAEFFYVLKANQSLKHLRLSANVLLDEGAMLLYKTMTRPKHFLQMLSLENCRLTEASCKDLAAVLVVSKKLTHLCLAKNPIGDTGVKFLCEGLSYPDCKLQTLVLQQCSITKLGCRYLSEALQEACSLTNLDLSINQIARGLWILCQALENPNCNLKHLRLKTYETNLEIKKLLEEVKEKNPKLTIDCNASGATAPPCCDFFC

Target ORF information:

RefSeq Version	XM_011526601.2
Organism	Homo sapiens(human)
Definition	Homo sapiens NLR family pyrin domain containing 7 (NLRP7), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011526601.2

ORF Insert Sequence:

ATGTCAAGGA AACACAGGCT GGAAGCAAGA CCTGACCTGA GGGAGTTCTT CAGCCTTAAC 
CTAAGGTCTC ATACTCGGAG CACTATGACA TCGCCCCAGC TAGAGTGGAC TCTGCAGACC 
CTTCTGGAGC AGCTGAACGA GGATGAATTA AAGAGTTTCA AATCCCTTTT ATGGGCTTTT 
CCCCTCGAAG ACGTGCTACA GAAGACCCCA TGGTCTGAGG TGGAAGAGGC TGATGGCAAG 
AAACTGGCAG AAATTCTGGT CAACACCTCC TCAGAAAATT GGATAAGGAA TGCGACTGTG 
AACATCTTGG AAGAGATGAA TCTCACGGAA TTGTGTAAGA TGGCAAAGGC TGAGATGATG 
GAGGACGGAC AGGTGCAAGA AATAGATAAT CCTGAGCTGG GAGATGCAGA AGAAGACTCG 
GAGTTAGCAA AGCCAGGTGA AAAGGAAGGA TGGAGAAATT CAATGGAGAA ACAGTCTTTG 
GTCTGGAAGA ACACCTTTTG GCAAGGAGAC ATTGACAATT TCCATGACGA CGTCACTCTG 
AGAAACCAAC GGTTCATTCC ATTCTTGAAT CCCAGAACAC CCAGGAAGCT AACACCTTAC 
ACGGTGGTGC TGCACGGCCC CGCAGGCGTG GGGAAAACCA CGCTGGCCAA AAAGTGTATG 
CTGGACTGGA CAGACTGCAA CCTCAGCCCG ACGCTCAGAT ACGCGTTCTA CCTCAGCTGC 
AAGGAGCTCA GCCGCATGGG CCCCTGCAGT TTTGCAGAGC TGATCTCCAA AGACTGGCCT 
GAATTGCAGG ATGACATTCC AAGCATCCTA GCCCAAGCAC AGAGAATCCT GTTCGTGGTC 
GATGGCCTTG ATGAGCTGAA AGTCCCACCT GGGGCGCTGA TCCAGGACAT CTGCGGGGAC 
TGGGAGAAGA AGAAGCCGGT GCCCGTCCTC CTGGGGAGTT TGCTGAAGAG GAAGATGTTA 
CCCAGGGCAG CCTTGCTGGT CACCACGCGG CCCAGGGCAC TGAGGGACCT CCAGCTCCTG 
GCGCAGCAGC CGATCTACGT AAGGGTGGAG GGCTTCCTGG AGGAGGACAG GAGGGCCTAT 
TTCCTGAGAC ACTTTGGAGA CGAGGACCAA GCCATGCGTG CCTTTGAGCT AATGAGGAGC 
AACGCGGCCC TGTTCCAGCT GGGCTCGGCC CCCGCGGTGT GCTGGATTGT GTGCACGACT 
CTGAAGCTGC AGATGGAGAA GGGGGAGGAC CCGGTCCCCA CCTGCCTCAC CCGCACGGGG 
CTGTTCCTGC GTTTCCTCTG CAGCCGGTTC CCGCAGGGCG CACAGCTGCG GGGCGCGCTG 
CGGACGCTGA GCCTCCTGGC CGCGCAGGGC CTGTGGGCGC AGATGTCCGT GTTCCACCGA 
GAGGACCTGG AAAGGCTCGG GGTGCAGGAG TCCGACCTCC GTCTGTTCCT GGACGGAGAC 
ATCCTCCGCC AGGACAGAGT CTCCAAAGGC TGCTACTCCT TCATCCACCT CAGCTTCCAG 
CAGTTTCTCA CTGCCCTGTT CTACGCCCTG GAGAAGGAGG AGGGGGAGGA CAGGGACGGC 
CACGCCTGGG ACATCGGGGA CGTACAGAAG CTGCTTTCCG GAGAAGAAAG ACTCAAGAAC 
CCCGACCTGA TTCAAGTAGG ACACTTCTTA TTCGGCCTCG CTAACGAGAA GAGAGCCAAG 
GAGTTGGAGG CCACTTTTGG CTGCCGGATG TCACCGGACA TCAAACAGGA ATTGCTGCAA 
TGCAAAGCAC ATCTTCATGC AAATAAGCCC TTATCCGTGA CCGACCTGAA GGAGGTCTTG 
GGCTGCCTGT ATGAGTCTCA GGAGGAGGAG CTGGCGAAGG TGGTGGTGGC CCCGTTCAAG 
GAAATTTCTA TTCACCTGAC AAATACTTCT GAAGTGATGC ATTGTTCCTT CAGCCTGAAG 
CATTGTCAAG ACTTGCAGAA ACTCTCACTG CAGGTAGCAA AGGGGGTGTT CCTGGAGAAT 
TACATGGATT TTGAACTGGA CATTGAATTT GAAAGGTGCA CTTACCTAAC CATTCCGAAC 
TGGGCTCGGC AGGATCTTCG CTCTCTTCGC CTCTGGACAG ATTTCTGCTC TCTCTTCAGC 
TCAAACAGCA ACCTCAAGTT TCTGGAAGTG AAACAAAGCT TCCTGAGTGA CTCTTCTGTG 
CGGATTCTTT GTGACCACGT AACCCGTAGC ACCTGTCATC TGCAGAAAGT GGAGATTAAA 
AACGTCACCC CTGACACCGC GTACCGGGAC TTCTGTCTTG CTTTCATTGG GAAGAAGACC 
CTCACGCACC TGACCCTGGC AGGGCACATC GAGTGGGAAC GCACGATGAT GCTGATGCTG 
TGTGACCTGC TCAGAAATCA TAAATGCAAC CTGCAGTACC TGAGGTTGGG AGGTCACTGT 
GCCACCCCGG AGCAGTGGGC TGAATTCTTC TATGTCCTCA AAGCCAACCA GTCCCTGAAG 
CACCTGCGTC TCTCAGCCAA TGTGCTCCTG GATGAGGGTG CCATGTTGCT GTACAAGACC 
ATGACACGCC CAAAACACTT CCTGCAGATG TTGTCGTTGG AAAACTGTCG TCTTACAGAA 
GCCAGTTGCA AGGACCTTGC TGCTGTCTTG GTTGTCAGCA AGAAGCTGAC ACACCTGTGC 
TTGGCCAAGA ACCCCATTGG GGATACAGGG GTGAAGTTTC TGTGTGAGGG CTTGAGTTAC 
CCTGATTGTA AACTGCAGAC CTTGGTGTTA CAGCAATGCA GCATAACCAA GCTTGGCTGT 
AGATATCTCT CAGAGGCGCT CCAAGAAGCC TGCAGCCTCA CAAACCTGGA CTTGAGTATC 
AACCAGATAG CTCGTGGATT GTGGATTCTC TGTCAGGCAT TAGAGAATCC AAACTGTAAC 
CTAAAACACC TACGGTTGAA GACCTATGAA ACTAATTTGG AAATCAAGAA GCTGTTGGAG 
GAAGTGAAAG AAAAGAATCC CAAGCTGACT ATTGATTGCA ATGCTTCCGG GGCAACGGCA 
CCTCCGTGCT GTGACTTTTT TTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Exome sequencing and genotyping identify a rare variant in NLRP7 gene associated with ulcerative colitis.
Journal of Crohn's & colitis(2017 Dec)
Onoufriadis A,Stone K,Katsiamides A,Amar A,Omar Y,de Lange K,Taylor K,Barrett JC,Pollok R,Hayee B,Mansfield JC,Sanderson JD,Simpson MA,Mathew CG,Prescott NJ

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NLRP7 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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