EIF4E cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	EIF4E
Entrez Gene ID	1977
Full Name	eukaryotic translation initiation factor 4E
Synonyms	AUTS19,CBP,EIF4E1,EIF4EL1,EIF4F,eIF-4E
General protein information	Preferred Names eukaryotic translation initiation factor 4E Names eukaryotic translation initiation factor 4E eIF-4F 25 kDa subunit eukaryotic translation initiation factor 4E-like 1 mRNA cap-binding protein
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 4 Map Location: 4q23
Summary	The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015].
Disorder MIM:	133440
Disorder Html:	{Autism, susceptibility to, 19}, 615091 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001331017.1	NP_001317946.1	eukaryotic translation initiation factor 4E isoform 4
NM_001130678.2	NP_001124150.1	eukaryotic translation initiation factor 4E isoform 3
NM_001968.3	NP_001959.1	eukaryotic translation initiation factor 4E isoform 1
NM_001130678.3	NP_001124150.1	eukaryotic translation initiation factor 4E isoform 3
NM_001130679.2	NP_001124151.1	eukaryotic translation initiation factor 4E isoform 2
NM_001968.4	NP_001959.1	eukaryotic translation initiation factor 4E isoform 1
NM_001130678.1	NP_001124150.1	eukaryotic translation initiation factor 4E isoform 3

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	EIF4E	XP_005639275.1
Rattus norvegicus (Norway rat)	Eif4e	NP_446426.1
Danio rerio (zebrafish)	eif4ea	NP_571808.1
Drosophila melanogaster (fruit fly)	eIF4E-5	NP_648160.2
Danio rerio (zebrafish)	eif4eb	NP_001007778.1
Xenopus tropicalis (tropical clawed frog)	eif4e	NP_001015909.1
Homo sapiens (human)	EIF4E	NP_001124151.1
Bos taurus (cattle)	EIF4E	NP_776735.2
Mus musculus (house mouse)	Eif4e	NP_031943.3
Drosophila melanogaster (fruit fly)	eIF4E-3	NP_648194.1
Pan troglodytes (chimpanzee)	EIF4E	NP_001233399.1
	EIF4E	XP_001104976.1
Drosophila melanogaster (fruit fly)	eIF-4E	NP_729485.1
Drosophila melanogaster (fruit fly)	eIF4E-7	NP_726718.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007172	XP_001688027.1
Arabidopsis thaliana (thale cress)	EIF4E	NP_193538.1
Gallus gallus (chicken)	EIF4E	XP_420655.4
Drosophila melanogaster (fruit fly)	eIF4E-4	NP_648052.1
Caenorhabditis elegans (roundworm)	ife-3	NP_503124.1
Oryza sativa (rice)	Os01g0970400	NP_001045525.1

Gene Ontology
Bibliography

Related articles in PubMed

An eIF4E1/4E-T complex determines the genesis of neurons from precursors by translationally repressing a proneurogenic transcription program.
Yang G, Smibert CA, Kaplan DR, Miller FD
Neuron84(4)723-39(2014 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PRMT1 inhibition prevents gastric cancer progression by downregulating eIF4E and targeting type II PRMT5.
Title: Arginine methyltransferase inhibitor 1 inhibits gastric cancer by downregulating eIF4E and targeting PRMT5.

Here, the authors identify the domains responsible for the eIF4E/human rhinovirus 2 2A(pro) interaction using molecular modelling and describe mutations that impair this interaction and delay in vitro cleavage of eIF4G isoforms.
Title: Interaction of 2A proteinase of human rhinovirus genetic group A with eIF4E is required for eIF4G cleavage during infection.

Data indicate that combinations of androgen receptor (AR) and mechanistic target of rapamycin (mTOR) inhibitors were effective in suppressing tumor growth including bicalutamide increased eukaryotic initiation factor 4E (eIF4E) phosphorylation.
Title: The androgen receptor is a negative regulator of eIF4E phosphorylation at S209: implications for the use of mTOR inhibitors in advanced prostate cancer.

There were significantly higher expressions of p-eIF4E and p-4EBP-1 proteins in the cases with lymph node metastasis than in those without lymph node metastasis.
Title: [Over-expressions of p-eIF4E and p-4EBP1 are associated with poor prognosis in nasopharyngeal carcinoma].

Findings suggest that miR-455-3p functions as a tumor suppressor by directly targeting eIF4E in prostate carcinogenesis.
Title: MicroRNA-455-3p functions as a tumor suppressor by targeting eIF4E in prostate cancer.

The following EIF4E gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EIF4E cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26101	NM_001968.4 Latest version!	Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu26347	NM_001130678.3 Latest version!	Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu26999	NM_001130679.2 Latest version!	Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu38754	NM_001331017.1 Latest version!	Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu26347	NM_001130678.2	Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu26101	NM_001968.3	Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu26347	NM_001130678.1	Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

EIF4E ( NM_001968.3 ) cDNA ORF clone, Homo sapiens(Human) -> NP_001959.1 Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu26101
Clone ID Related Accession (Same CDS sequence)	NM_001968.3 , NM_001968.4
Accession Version	NM_001968.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	eukaryotic translation initiation factor 4E isoform 1
Comment

ATGGCGACTG TCGAACCGGA AACCACCCCT ACTCCTAATC CCCCGACTAC AGAAGAGGAG 
AAAACGGAAT CTAATCAGGA GGTTGCTAAC CCAGAACACT ATATTAAACA TCCCCTACAG 
AACAGATGGG CACTCTGGTT TTTTAAAAAT GATAAAAGCA AAACTTGGCA AGCAAACCTG 
CGGCTGATCT CCAAGTTTGA TACTGTTGAA GACTTTTGGG CTCTGTACAA CCATATCCAG 
TTGTCTAGTA ATTTAATGCC TGGCTGTGAC TACTCACTTT TTAAGGATGG TATTGAGCCT 
ATGTGGGAAG ATGAGAAAAA CAAACGGGGA GGACGATGGC TAATTACATT GAACAAACAG 
CAGAGACGAA GTGACCTCGA TCGCTTTTGG CTAGAGACAC TTCTGTGCCT TATTGGAGAA 
TCTTTTGATG ACTACAGTGA TGATGTATGT GGCGCTGTTG TTAATGTTAG AGCTAAAGGT 
GATAAGATAG CAATATGGAC TACTGAATGT GAAAACAGAG AAGCTGTTAC ACATATAGGG 
AGGGTATACA AGGAAAGGTT AGGACTTCCT CCAAAGATAG TGATTGGTTA TCAGTCCCAC 
GCAGACACAG CTACTAAGAG CGGCTCCACC ACTAAAAATA GGTTTGTTGT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001959.1
Translation	MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV

Target ORF information:

RefSeq Version	NM_001968.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001968.3

ORF Insert Sequence:

ATGGCGACTG TCGAACCGGA AACCACCCCT ACTCCTAATC CCCCGACTAC AGAAGAGGAG 
AAAACGGAAT CTAATCAGGA GGTTGCTAAC CCAGAACACT ATATTAAACA TCCCCTACAG 
AACAGATGGG CACTCTGGTT TTTTAAAAAT GATAAAAGCA AAACTTGGCA AGCAAACCTG 
CGGCTGATCT CCAAGTTTGA TACTGTTGAA GACTTTTGGG CTCTGTACAA CCATATCCAG 
TTGTCTAGTA ATTTAATGCC TGGCTGTGAC TACTCACTTT TTAAGGATGG TATTGAGCCT 
ATGTGGGAAG ATGAGAAAAA CAAACGGGGA GGACGATGGC TAATTACATT GAACAAACAG 
CAGAGACGAA GTGACCTCGA TCGCTTTTGG CTAGAGACAC TTCTGTGCCT TATTGGAGAA 
TCTTTTGATG ACTACAGTGA TGATGTATGT GGCGCTGTTG TTAATGTTAG AGCTAAAGGT 
GATAAGATAG CAATATGGAC TACTGAATGT GAAAACAGAG AAGCTGTTAC ACATATAGGG 
AGGGTATACA AGGAAAGGTT AGGACTTCCT CCAAAGATAG TGATTGGTTA TCAGTCCCAC 
GCAGACACAG CTACTAAGAG CGGCTCCACC ACTAAAAATA GGTTTGTTGT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF4E ( NM_001968.4 ) cDNA ORF clone, Homo sapiens(Human) -> NP_001959.1 Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu26101
Clone ID Related Accession (Same CDS sequence)	NM_001968.3 , NM_001968.4
Accession Version	NM_001968.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	eukaryotic translation initiation factor 4E isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC035166.1, AC019131.7, M15353.1, AC093836.3 and R61891.1. On Sep 3, 2016 this sequence version replaced NM_001968.3. Transcript Variant: This variant (1) encodes the shortest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.164252.1, SRR1660807.189444.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGACTG TCGAACCGGA AACCACCCCT ACTCCTAATC CCCCGACTAC AGAAGAGGAG 
AAAACGGAAT CTAATCAGGA GGTTGCTAAC CCAGAACACT ATATTAAACA TCCCCTACAG 
AACAGATGGG CACTCTGGTT TTTTAAAAAT GATAAAAGCA AAACTTGGCA AGCAAACCTG 
CGGCTGATCT CCAAGTTTGA TACTGTTGAA GACTTTTGGG CTCTGTACAA CCATATCCAG 
TTGTCTAGTA ATTTAATGCC TGGCTGTGAC TACTCACTTT TTAAGGATGG TATTGAGCCT 
ATGTGGGAAG ATGAGAAAAA CAAACGGGGA GGACGATGGC TAATTACATT GAACAAACAG 
CAGAGACGAA GTGACCTCGA TCGCTTTTGG CTAGAGACAC TTCTGTGCCT TATTGGAGAA 
TCTTTTGATG ACTACAGTGA TGATGTATGT GGCGCTGTTG TTAATGTTAG AGCTAAAGGT 
GATAAGATAG CAATATGGAC TACTGAATGT GAAAACAGAG AAGCTGTTAC ACATATAGGG 
AGGGTATACA AGGAAAGGTT AGGACTTCCT CCAAAGATAG TGATTGGTTA TCAGTCCCAC 
GCAGACACAG CTACTAAGAG CGGCTCCACC ACTAAAAATA GGTTTGTTGT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001959.1
CDS	1526..2179
Translation	MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV

Target ORF information:

RefSeq Version	NM_001968.4
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001968.4

ORF Insert Sequence:

ATGGCGACTG TCGAACCGGA AACCACCCCT ACTCCTAATC CCCCGACTAC AGAAGAGGAG 
AAAACGGAAT CTAATCAGGA GGTTGCTAAC CCAGAACACT ATATTAAACA TCCCCTACAG 
AACAGATGGG CACTCTGGTT TTTTAAAAAT GATAAAAGCA AAACTTGGCA AGCAAACCTG 
CGGCTGATCT CCAAGTTTGA TACTGTTGAA GACTTTTGGG CTCTGTACAA CCATATCCAG 
TTGTCTAGTA ATTTAATGCC TGGCTGTGAC TACTCACTTT TTAAGGATGG TATTGAGCCT 
ATGTGGGAAG ATGAGAAAAA CAAACGGGGA GGACGATGGC TAATTACATT GAACAAACAG 
CAGAGACGAA GTGACCTCGA TCGCTTTTGG CTAGAGACAC TTCTGTGCCT TATTGGAGAA 
TCTTTTGATG ACTACAGTGA TGATGTATGT GGCGCTGTTG TTAATGTTAG AGCTAAAGGT 
GATAAGATAG CAATATGGAC TACTGAATGT GAAAACAGAG AAGCTGTTAC ACATATAGGG 
AGGGTATACA AGGAAAGGTT AGGACTTCCT CCAAAGATAG TGATTGGTTA TCAGTCCCAC 
GCAGACACAG CTACTAAGAG CGGCTCCACC ACTAAAAATA GGTTTGTTGT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF4E ( NM_001130678.2 ) cDNA ORF clone, Homo sapiens(Human) -> NP_001124150.1 Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu26347
Clone ID Related Accession (Same CDS sequence)	NM_001130678.2 , NM_001130678.3 , NM_001130678.1
Accession Version	NM_001130678.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-25
Organism	Homo sapiens(human)
Product	eukaryotic translation initiation factor 4E isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC388666.1, BC107715.1, AC093836.3 and R61891.1. On Sep 3, 2016 this sequence version replaced NM_001130678.1. Transcript Variant: This variant (3) uses an alternate 5'-terminal exon, which results in a different 5' UTR and use of an alternate translation start codon compared to variant 1. It encodes isoform 3, which has a distinct N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK300982.1, SRR1660807.43761.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGGACC TGACCTCCCG CGGACAAGTG GGGACGTCCC GGAGGATGGC CGAGGCGGCG 
TGTAGCGCAC ACTTTCTGGA AACCACCCCT ACTCCTAATC CCCCGACTAC AGAAGAGGAG 
AAAACGGAAT CTAATCAGGA GGTTGCTAAC CCAGAACACT ATATTAAACA TCCCCTACAG 
AACAGATGGG CACTCTGGTT TTTTAAAAAT GATAAAAGCA AAACTTGGCA AGCAAACCTG 
CGGCTGATCT CCAAGTTTGA TACTGTTGAA GACTTTTGGG CTCTGTACAA CCATATCCAG 
TTGTCTAGTA ATTTAATGCC TGGCTGTGAC TACTCACTTT TTAAGGATGG TATTGAGCCT 
ATGTGGGAAG ATGAGAAAAA CAAACGGGGA GGACGATGGC TAATTACATT GAACAAACAG 
CAGAGACGAA GTGACCTCGA TCGCTTTTGG CTAGAGACAC TTCTGTGCCT TATTGGAGAA 
TCTTTTGATG ACTACAGTGA TGATGTATGT GGCGCTGTTG TTAATGTTAG AGCTAAAGGT 
GATAAGATAG CAATATGGAC TACTGAATGT GAAAACAGAG AAGCTGTTAC ACATATAGGG 
AGGGTATACA AGGAAAGGTT AGGACTTCCT CCAAAGATAG TGATTGGTTA TCAGTCCCAC 
GCAGACACAG CTACTAAGAG CGGCTCCACC ACTAAAAATA GGTTTGTTGT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001124150.1
CDS	121..834
Translation	MLDLTSRGQVGTSRRMAEAACSAHFLETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV

Target ORF information:

RefSeq Version	NM_001130678.2
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001130678.2

ORF Insert Sequence:

ATGTTGGACC TGACCTCCCG CGGACAAGTG GGGACGTCCC GGAGGATGGC CGAGGCGGCG 
TGTAGCGCAC ACTTTCTGGA AACCACCCCT ACTCCTAATC CCCCGACTAC AGAAGAGGAG 
AAAACGGAAT CTAATCAGGA GGTTGCTAAC CCAGAACACT ATATTAAACA TCCCCTACAG 
AACAGATGGG CACTCTGGTT TTTTAAAAAT GATAAAAGCA AAACTTGGCA AGCAAACCTG 
CGGCTGATCT CCAAGTTTGA TACTGTTGAA GACTTTTGGG CTCTGTACAA CCATATCCAG 
TTGTCTAGTA ATTTAATGCC TGGCTGTGAC TACTCACTTT TTAAGGATGG TATTGAGCCT 
ATGTGGGAAG ATGAGAAAAA CAAACGGGGA GGACGATGGC TAATTACATT GAACAAACAG 
CAGAGACGAA GTGACCTCGA TCGCTTTTGG CTAGAGACAC TTCTGTGCCT TATTGGAGAA 
TCTTTTGATG ACTACAGTGA TGATGTATGT GGCGCTGTTG TTAATGTTAG AGCTAAAGGT 
GATAAGATAG CAATATGGAC TACTGAATGT GAAAACAGAG AAGCTGTTAC ACATATAGGG 
AGGGTATACA AGGAAAGGTT AGGACTTCCT CCAAAGATAG TGATTGGTTA TCAGTCCCAC 
GCAGACACAG CTACTAAGAG CGGCTCCACC ACTAAAAATA GGTTTGTTGT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF4E ( NM_001130678.3 ) cDNA ORF clone, Homo sapiens(Human) -> NP_001124150.1 Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu26347
Clone ID Related Accession (Same CDS sequence)	NM_001130678.2 , NM_001130678.3 , NM_001130678.1
Accession Version	NM_001130678.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-20
Organism	Homo sapiens(human)
Product	eukaryotic translation initiation factor 4E isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC019131.7, DC388666.1, BC107715.1, AC093836.3 and R61891.1. On Jun 2, 2019 this sequence version replaced NM_001130678.2. Transcript Variant: This variant (3) uses an alternate 5'-terminal exon, which results in a different 5' UTR and use of an alternate translation start codon compared to variant 1. It encodes isoform 3, which has a distinct N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.43761.1, SRR1803611.124309.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTGGACC TGACCTCCCG CGGACAAGTG GGGACGTCCC GGAGGATGGC CGAGGCGGCG 
TGTAGCGCAC ACTTTCTGGA AACCACCCCT ACTCCTAATC CCCCGACTAC AGAAGAGGAG 
AAAACGGAAT CTAATCAGGA GGTTGCTAAC CCAGAACACT ATATTAAACA TCCCCTACAG 
AACAGATGGG CACTCTGGTT TTTTAAAAAT GATAAAAGCA AAACTTGGCA AGCAAACCTG 
CGGCTGATCT CCAAGTTTGA TACTGTTGAA GACTTTTGGG CTCTGTACAA CCATATCCAG 
TTGTCTAGTA ATTTAATGCC TGGCTGTGAC TACTCACTTT TTAAGGATGG TATTGAGCCT 
ATGTGGGAAG ATGAGAAAAA CAAACGGGGA GGACGATGGC TAATTACATT GAACAAACAG 
CAGAGACGAA GTGACCTCGA TCGCTTTTGG CTAGAGACAC TTCTGTGCCT TATTGGAGAA 
TCTTTTGATG ACTACAGTGA TGATGTATGT GGCGCTGTTG TTAATGTTAG AGCTAAAGGT 
GATAAGATAG CAATATGGAC TACTGAATGT GAAAACAGAG AAGCTGTTAC ACATATAGGG 
AGGGTATACA AGGAAAGGTT AGGACTTCCT CCAAAGATAG TGATTGGTTA TCAGTCCCAC 
GCAGACACAG CTACTAAGAG CGGCTCCACC ACTAAAAATA GGTTTGTTGT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001124150.1
CDS	162..875
Translation	MLDLTSRGQVGTSRRMAEAACSAHFLETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV

Target ORF information:

RefSeq Version	NM_001130678.3
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001130678.3

ORF Insert Sequence:

ATGTTGGACC TGACCTCCCG CGGACAAGTG GGGACGTCCC GGAGGATGGC CGAGGCGGCG 
TGTAGCGCAC ACTTTCTGGA AACCACCCCT ACTCCTAATC CCCCGACTAC AGAAGAGGAG 
AAAACGGAAT CTAATCAGGA GGTTGCTAAC CCAGAACACT ATATTAAACA TCCCCTACAG 
AACAGATGGG CACTCTGGTT TTTTAAAAAT GATAAAAGCA AAACTTGGCA AGCAAACCTG 
CGGCTGATCT CCAAGTTTGA TACTGTTGAA GACTTTTGGG CTCTGTACAA CCATATCCAG 
TTGTCTAGTA ATTTAATGCC TGGCTGTGAC TACTCACTTT TTAAGGATGG TATTGAGCCT 
ATGTGGGAAG ATGAGAAAAA CAAACGGGGA GGACGATGGC TAATTACATT GAACAAACAG 
CAGAGACGAA GTGACCTCGA TCGCTTTTGG CTAGAGACAC TTCTGTGCCT TATTGGAGAA 
TCTTTTGATG ACTACAGTGA TGATGTATGT GGCGCTGTTG TTAATGTTAG AGCTAAAGGT 
GATAAGATAG CAATATGGAC TACTGAATGT GAAAACAGAG AAGCTGTTAC ACATATAGGG 
AGGGTATACA AGGAAAGGTT AGGACTTCCT CCAAAGATAG TGATTGGTTA TCAGTCCCAC 
GCAGACACAG CTACTAAGAG CGGCTCCACC ACTAAAAATA GGTTTGTTGT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF4E ( NM_001130678.1 ) cDNA ORF clone, Homo sapiens(Human) -> NP_001124150.1 Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 3, mRNA.

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CloneID	OHu26347
Clone ID Related Accession (Same CDS sequence)	NM_001130678.2 , NM_001130678.3 , NM_001130678.1
Accession Version	NM_001130678.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	eukaryotic translation initiation factor 4E isoform 3
Comment

ATGTTGGACC TGACCTCCCG CGGACAAGTG GGGACGTCCC GGAGGATGGC CGAGGCGGCG 
TGTAGCGCAC ACTTTCTGGA AACCACCCCT ACTCCTAATC CCCCGACTAC AGAAGAGGAG 
AAAACGGAAT CTAATCAGGA GGTTGCTAAC CCAGAACACT ATATTAAACA TCCCCTACAG 
AACAGATGGG CACTCTGGTT TTTTAAAAAT GATAAAAGCA AAACTTGGCA AGCAAACCTG 
CGGCTGATCT CCAAGTTTGA TACTGTTGAA GACTTTTGGG CTCTGTACAA CCATATCCAG 
TTGTCTAGTA ATTTAATGCC TGGCTGTGAC TACTCACTTT TTAAGGATGG TATTGAGCCT 
ATGTGGGAAG ATGAGAAAAA CAAACGGGGA GGACGATGGC TAATTACATT GAACAAACAG 
CAGAGACGAA GTGACCTCGA TCGCTTTTGG CTAGAGACAC TTCTGTGCCT TATTGGAGAA 
TCTTTTGATG ACTACAGTGA TGATGTATGT GGCGCTGTTG TTAATGTTAG AGCTAAAGGT 
GATAAGATAG CAATATGGAC TACTGAATGT GAAAACAGAG AAGCTGTTAC ACATATAGGG 
AGGGTATACA AGGAAAGGTT AGGACTTCCT CCAAAGATAG TGATTGGTTA TCAGTCCCAC 
GCAGACACAG CTACTAAGAG CGGCTCCACC ACTAAAAATA GGTTTGTTGT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001124150.1
Translation	MLDLTSRGQVGTSRRMAEAACSAHFLETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV

Target ORF information:

RefSeq Version	NM_001130678.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001130678.1

ORF Insert Sequence:

ATGTTGGACC TGACCTCCCG CGGACAAGTG GGGACGTCCC GGAGGATGGC CGAGGCGGCG 
TGTAGCGCAC ACTTTCTGGA AACCACCCCT ACTCCTAATC CCCCGACTAC AGAAGAGGAG 
AAAACGGAAT CTAATCAGGA GGTTGCTAAC CCAGAACACT ATATTAAACA TCCCCTACAG 
AACAGATGGG CACTCTGGTT TTTTAAAAAT GATAAAAGCA AAACTTGGCA AGCAAACCTG 
CGGCTGATCT CCAAGTTTGA TACTGTTGAA GACTTTTGGG CTCTGTACAA CCATATCCAG 
TTGTCTAGTA ATTTAATGCC TGGCTGTGAC TACTCACTTT TTAAGGATGG TATTGAGCCT 
ATGTGGGAAG ATGAGAAAAA CAAACGGGGA GGACGATGGC TAATTACATT GAACAAACAG 
CAGAGACGAA GTGACCTCGA TCGCTTTTGG CTAGAGACAC TTCTGTGCCT TATTGGAGAA 
TCTTTTGATG ACTACAGTGA TGATGTATGT GGCGCTGTTG TTAATGTTAG AGCTAAAGGT 
GATAAGATAG CAATATGGAC TACTGAATGT GAAAACAGAG AAGCTGTTAC ACATATAGGG 
AGGGTATACA AGGAAAGGTT AGGACTTCCT CCAAAGATAG TGATTGGTTA TCAGTCCCAC 
GCAGACACAG CTACTAAGAG CGGCTCCACC ACTAAAAATA GGTTTGTTGT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF4E ( NM_001130679.2 ) cDNA ORF clone, Homo sapiens(Human) -> NP_001124151.1 Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 2, mRNA.

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CloneID	OHu26999
Clone ID Related Accession (Same CDS sequence)	NM_001130679.2
Accession Version	NM_001130679.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 747bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	eukaryotic translation initiation factor 4E isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC035166.1, AC019131.7, BM849222.1, AC093836.3 and R61891.1. This sequence is a reference standard in the RefSeqGene project. On Sep 3, 2016 this sequence version replaced NM_001130679.1. Transcript Variant: This variant (2) contains an alternate in-frame exon in the 3' coding region compared to variant 1. It encodes isoform 2, which is longer than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because transcript sequence consistent with the reference genome assembly was not available for all regions of the RefSeq transcript. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.86698.1, SRR1660809.41736.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGACTG TCGAACCGGA AACCACCCCT ACTCCTAATC CCCCGACTAC AGAAGAGGAG 
AAAACGGAAT CTAATCAGGA GGTTGCTAAC CCAGAACACT ATATTAAACA TCCCCTACAG 
AACAGATGGG CACTCTGGTT TTTTAAAAAT GATAAAAGCA AAACTTGGCA AGCAAACCTG 
CGGCTGATCT CCAAGTTTGA TACTGTTGAA GACTTTTGGG CTCTGTACAA CCATATCCAG 
TTGTCTAGTA ATTTAATGCC TGGCTGTGAC TACTCACTTT TTAAGGATGG TATTGAGCCT 
ATGTGGGAAG ATGAGAAAAA CAAACGGGGA GGACGATGGC TAATTACATT GAACAAACAG 
CAGAGACGAA GTGACCTCGA TCGCTTTTGG CTAGAGACAA GATGGGATCT TGCTATGTTG 
CCCAGGTTGG TCTCAAACTT CTGGCCTCAA GTGATCCTCC CACTTCAGCC TCCCAAAGTG 
CTGGAATTAC AGCTTCTGTG CCTTATTGGA GAATCTTTTG ATGACTACAG TGATGATGTA 
TGTGGCGCTG TTGTTAATGT TAGAGCTAAA GGTGATAAGA TAGCAATATG GACTACTGAA 
TGTGAAAACA GAGAAGCTGT TACACATATA GGGAGGGTAT ACAAGGAAAG GTTAGGACTT 
CCTCCAAAGA TAGTGATTGG TTATCAGTCC CACGCAGACA CAGCTACTAA GAGCGGCTCC 
ACCACTAAAA ATAGGTTTGT TGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001124151.1
CDS	1526..2272
Translation	MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETRWDLAMLPRLVSNFWPQVILPLQPPKVLELQLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV

Target ORF information:

RefSeq Version	NM_001130679.2
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001130679.2

ORF Insert Sequence:

ATGGCGACTG TCGAACCGGA AACCACCCCT ACTCCTAATC CCCCGACTAC AGAAGAGGAG 
AAAACGGAAT CTAATCAGGA GGTTGCTAAC CCAGAACACT ATATTAAACA TCCCCTACAG 
AACAGATGGG CACTCTGGTT TTTTAAAAAT GATAAAAGCA AAACTTGGCA AGCAAACCTG 
CGGCTGATCT CCAAGTTTGA TACTGTTGAA GACTTTTGGG CTCTGTACAA CCATATCCAG 
TTGTCTAGTA ATTTAATGCC TGGCTGTGAC TACTCACTTT TTAAGGATGG TATTGAGCCT 
ATGTGGGAAG ATGAGAAAAA CAAACGGGGA GGACGATGGC TAATTACATT GAACAAACAG 
CAGAGACGAA GTGACCTCGA TCGCTTTTGG CTAGAGACAA GATGGGATCT TGCTATGTTG 
CCCAGGTTGG TCTCAAACTT CTGGCCTCAA GTGATCCTCC CACTTCAGCC TCCCAAAGTG 
CTGGAATTAC AGCTTCTGTG CCTTATTGGA GAATCTTTTG ATGACTACAG TGATGATGTA 
TGTGGCGCTG TTGTTAATGT TAGAGCTAAA GGTGATAAGA TAGCAATATG GACTACTGAA 
TGTGAAAACA GAGAAGCTGT TACACATATA GGGAGGGTAT ACAAGGAAAG GTTAGGACTT 
CCTCCAAAGA TAGTGATTGG TTATCAGTCC CACGCAGACA CAGCTACTAA GAGCGGCTCC 
ACCACTAAAA ATAGGTTTGT TGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF4E ( NM_001331017.1 ) cDNA ORF clone, Homo sapiens(Human) -> NP_001317946.1 Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 4, mRNA.

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CloneID	OHu38754
Clone ID Related Accession (Same CDS sequence)	NM_001331017.1
Accession Version	NM_001331017.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 738bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	eukaryotic translation initiation factor 4E isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC035166.1, AC019131.7, BY994926.1, M15353.1, AC093836.3 and R61891.1. On Sep 3, 2016 this sequence version replaced XM_006714126.3. Transcript Variant: This variant (4) differs in its 5' UTR and contains an alternate exon in its 5' coding region compared to variant 1. This variant represents translation initiation at an alternate start codon compared to variant 1; the 5'-most initiation codon, as used in variant 1, is associated with a truncated ORF that would render the transcript a candidate for nonsense-mediated decay (NMD). Leaky scanning may allow translation initiation at the alternate start codon to encode an isoform (4) that has a longer and distinct N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.247703.1, SRR1660809.132706.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAAAAGA AGCAAAACAA GAAGGAAAGA AAAAAAATGA GAGCTGAAGA TGGTGAAAAT 
GATGCCATTA AAAAGCAGGC AGAAAGTCTG CGAGAATCCC AGGAAACCAC CCCTACTCCT 
AATCCCCCGA CTACAGAAGA GGAGAAAACG GAATCTAATC AGGAGGTTGC TAACCCAGAA 
CACTATATTA AACATCCCCT ACAGAACAGA TGGGCACTCT GGTTTTTTAA AAATGATAAA 
AGCAAAACTT GGCAAGCAAA CCTGCGGCTG ATCTCCAAGT TTGATACTGT TGAAGACTTT 
TGGGCTCTGT ACAACCATAT CCAGTTGTCT AGTAATTTAA TGCCTGGCTG TGACTACTCA 
CTTTTTAAGG ATGGTATTGA GCCTATGTGG GAAGATGAGA AAAACAAACG GGGAGGACGA 
TGGCTAATTA CATTGAACAA ACAGCAGAGA CGAAGTGACC TCGATCGCTT TTGGCTAGAG 
ACACTTCTGT GCCTTATTGG AGAATCTTTT GATGACTACA GTGATGATGT ATGTGGCGCT 
GTTGTTAATG TTAGAGCTAA AGGTGATAAG ATAGCAATAT GGACTACTGA ATGTGAAAAC 
AGAGAAGCTG TTACACATAT AGGGAGGGTA TACAAGGAAA GGTTAGGACT TCCTCCAAAG 
ATAGTGATTG GTTATCAGTC CCACGCAGAC ACAGCTACTA AGAGCGGCTC CACCACTAAA 
AATAGGTTTG TTGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317946.1
CDS	1724..2461
Translation	MKKKQNKKERKKMRAEDGENDAIKKQAESLRESQETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV

Target ORF information:

RefSeq Version	NM_001331017.1
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001331017.1

ORF Insert Sequence:

ATGAAAAAGA AGCAAAACAA GAAGGAAAGA AAAAAAATGA GAGCTGAAGA TGGTGAAAAT 
GATGCCATTA AAAAGCAGGC AGAAAGTCTG CGAGAATCCC AGGAAACCAC CCCTACTCCT 
AATCCCCCGA CTACAGAAGA GGAGAAAACG GAATCTAATC AGGAGGTTGC TAACCCAGAA 
CACTATATTA AACATCCCCT ACAGAACAGA TGGGCACTCT GGTTTTTTAA AAATGATAAA 
AGCAAAACTT GGCAAGCAAA CCTGCGGCTG ATCTCCAAGT TTGATACTGT TGAAGACTTT 
TGGGCTCTGT ACAACCATAT CCAGTTGTCT AGTAATTTAA TGCCTGGCTG TGACTACTCA 
CTTTTTAAGG ATGGTATTGA GCCTATGTGG GAAGATGAGA AAAACAAACG GGGAGGACGA 
TGGCTAATTA CATTGAACAA ACAGCAGAGA CGAAGTGACC TCGATCGCTT TTGGCTAGAG 
ACACTTCTGT GCCTTATTGG AGAATCTTTT GATGACTACA GTGATGATGT ATGTGGCGCT 
GTTGTTAATG TTAGAGCTAA AGGTGATAAG ATAGCAATAT GGACTACTGA ATGTGAAAAC 
AGAGAAGCTG TTACACATAT AGGGAGGGTA TACAAGGAAA GGTTAGGACT TCCTCCAAAG 
ATAGTGATTG GTTATCAGTC CCACGCAGAC ACAGCTACTA AGAGCGGCTC CACCACTAAA 
AATAGGTTTG TTGTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

An eIF4E1/4E-T complex determines the genesis of neurons from precursors by translationally repressing a proneurogenic transcription program.
Neuron84(4)723-39(2014 Nov)
Yang G,Smibert CA,Kaplan DR,Miller FD

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EIF4E cDNA ORF clone, Homo sapiens(Human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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