The following EIF4B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EIF4B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu30924 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_001417.6 , NM_001417.5 | |
| Accession Version | NM_001417.6 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1836bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-03-03 | |
| Organism | Homo sapiens(human) | |
| Product | eukaryotic translation initiation factor 4B isoform 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from DC403237.1, BU431305.1, AB076839.1, BP243230.1 and AC068888.35. On Sep 1, 2016 this sequence version replaced NM_001417.5. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.85157.1, SRR1803617.42409.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length. | |
1 | ATGGCGGCCT CAGCAAAAAA GAAGAATAAG AAGGGGAAGA CTATCTCCCT AACAGACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001408.2 |
| CDS | 227..2062 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001417.6 |
1 | ATGGCGGCCT CAGCAAAAAA GAAGAATAAG AAGGGGAAGA CTATCTCCCT AACAGACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu30924 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_001417.6 , NM_001417.5 | |
| Accession Version | NM_001417.5 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1836bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2015-03-14 | |
| Organism | Homo sapiens(Human) | |
| Product | eukaryotic translation initiation factor 4B isoform 2 | |
| Comment | ||
1 | ATGGCGGCCT CAGCAAAAAA GAAGAATAAG AAGGGGAAGA CTATCTCCCT AACAGACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001408.2 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001417.5 |
1 | ATGGCGGCCT CAGCAAAAAA GAAGAATAAG AAGGGGAAGA CTATCTCCCT AACAGACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu57452 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_001300821.2 | |
| Accession Version | NM_001300821.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1851bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-03-03 | |
| Organism | Homo sapiens(human) | |
| Product | eukaryotic translation initiation factor 4B isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC403237.1, AC068888.35, AK299329.1 and BC001097.1. On Sep 1, 2016 this sequence version replaced NM_001300821.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.242454.1, SRR1803611.218631.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGCGGCCT CAGCAAAAAA GAAGAATAAG AAGGGGAAGA CTATCTCCCT AACAGACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001287750.1 |
| CDS | 227..2077 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001300821.2 |
1 | ATGGCGGCCT CAGCAAAAAA GAAGAATAAG AAGGGGAAGA CTATCTCCCT AACAGACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu100267 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001330654.1 | |
| Accession Version | NM_001330654.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1719bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-03-03 | |
| Organism | Homo sapiens(human) | |
| Product | eukaryotic translation initiation factor 4B isoform 3 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC403237.1, AC068888.35, AK299526.1 and BP243230.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK299526.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGCGGCCT CAGCAAAAAA GAAGAATAAG AAGGGGAAGA CTATCTCCCT AACAGACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001317583.1 |
| CDS | 227..1945 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001330654.1 |
1 | ATGGCGGCCT CAGCAAAAAA GAAGAATAAG AAGGGGAAGA CTATCTCCCT AACAGACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu108290 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001300821.3 | |
| Accession Version | NM_001300821.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1851bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Homo sapiens(human) | |
| Product | eukaryotic translation initiation factor 4B isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC068888.35. On Jun 2, 2019 this sequence version replaced NM_001300821.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK299329.1, SRR1803613.151194.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGCGGCCT CAGCAAAAAA GAAGAATAAG AAGGGGAAGA CTATCTCCCT AACAGACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001287750.1 |
| CDS | 29..1879 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001300821.3 |
1 | ATGGCGGCCT CAGCAAAAAA GAAGAATAAG AAGGGGAAGA CTATCTCCCT AACAGACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu108375 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001417.7 | |
| Accession Version | NM_001417.7 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1836bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Homo sapiens(human) | |
| Product | eukaryotic translation initiation factor 4B isoform 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from AC068888.35. On Jun 2, 2019 this sequence version replaced NM_001417.6. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.19838.1, SRR1803614.213627.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length. | |
1 | ATGGCGGCCT CAGCAAAAAA GAAGAATAAG AAGGGGAAGA CTATCTCCCT AACAGACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001408.2 |
| CDS | 29..1864 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001417.7 |
1 | ATGGCGGCCT CAGCAAAAAA GAAGAATAAG AAGGGGAAGA CTATCTCCCT AACAGACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu108383 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001330654.2 | |
| Accession Version | NM_001330654.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1719bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Homo sapiens(human) | |
| Product | eukaryotic translation initiation factor 4B isoform 3 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC068888.35. On Jun 2, 2019 this sequence version replaced NM_001330654.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK299526.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGCGGCCT CAGCAAAAAA GAAGAATAAG AAGGGGAAGA CTATCTCCCT AACAGACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001317583.1 |
| CDS | 29..1747 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001330654.2 |
1 | ATGGCGGCCT CAGCAAAAAA GAAGAATAAG AAGGGGAAGA CTATCTCCCT AACAGACTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Pim-2 Cooperates with Downstream Factor XIAP to Inhibit Apoptosis and Intensify Malignant Grade in Prostate Cancer. |
Muscarinic acetylcholine receptors mediate eIF4B phosphorylation in SNU-407 colon cancer cells. |
Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival. |
eIF4B is a convergent target and critical effector of oncogenic Pim and PI3K/Akt/mTOR signaling pathways in Abl transformants. |
