Gene Symbol | NLRC3 |
Entrez Gene ID | 197358 |
Full Name | NLR family CARD domain containing 3 |
Synonyms | CLR16.2,NOD3 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a NOD-like receptor family member. The encoded protein is a cytosolic regulator of innate immunity. This protein directly interacts with stimulator of interferon genes (STING), to prevent its proper trafficking, resulting in disruption of STING-dependent activation of the innate immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]. |
Disorder MIM: |