PAOX cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PAOX
Entrez Gene ID	196743
Full Name	polyamine oxidase
Synonyms	PAO
General protein information	Preferred Names polyamine oxidase Names peroxisomal N(1)-acetyl-spermine/spermidine oxidase peroxisomal N1-acetyl-spermine/spermidine oxidase polyamine oxidase (exo-N4-amino)
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10q26.3
Disorder MIM:	615853

mRNA and Protein(s)

mRNA	Protein	Name
NM_152911.4	NP_690875.1	peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 1
NM_207127.2	NP_997010.1	peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 2
NM_207127.3	NP_997010.1	peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 2
NM_207128.3	NP_997011.1	peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 4
NM_207128.2	NP_997011.1	peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 4
NM_152911.3	NP_690875.1	peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Paox	NP_001099781.1
Danio rerio (zebrafish)	si:dkey-275b16.2	XP_690593.2
Bos taurus (cattle)	PAOX	NP_001013620.2
Mus musculus (house mouse)	Paox	NP_722478.2
Gallus gallus (chicken)	PAOX	XP_003641516.1
Homo sapiens (human)	PAOX	NP_690875.1
Pan troglodytes (chimpanzee)	PAOX	XP_003312887.2

Gene Ontology
Bibliography

Related articles in PubMed

Integrative analysis of copy number and gene expression data suggests novel pathogenetic mechanisms in primary myelofibrosis.
Salati S, Zini R, Nuzzo S, Guglielmelli P, Pennucci V, Prudente Z, Ruberti S, Rontauroli S, Norfo R, Bianchi E, Bogani C, Rotunno G, Fanelli T, Mannarelli C, Rosti V, Salmoiraghi S, Pietra D, Ferrari S, Barosi G, Rambaldi A, Cazzola M, Bicciato S, Tagliafico E, Vannucchi AM, Manfredini R,
International journal of cancer138(7)1657-69(2016 Apr)

An atlas of genetic influences on human blood metabolites.
Shin SY, Fauman EB, Petersen AK, Krumsiek J, Santos R, Huang J, Arnold M, Erte I, Forgetta V, Yang TP, Walter K, Menni C, Chen L, Vasquez L, Valdes AM, Hyde CL, Wang V, Ziemek D, Roberts P, Xi L, Grundberg E, , Waldenberger M, Richards JB, Mohney RP, Milburn MV, John SL, Trimmer J, Theis FJ, Overington JP, Suhre K, Brosnan MJ, Gieger C, Kastenm?ller G, Spector TD, Soranzo N
Nature genetics46(6)543-550(2014 Jun)

Does polyamine oxidase activity influence the oxidative metabolism of children who suffer of diabetes mellitus?
Bjelakovic G, Beninati S, Bjelakovic B, Sokolovic D, Jevtovic T, Stojanovic I, Rossi S, Tabolacci C, Koci? G, Pavlovic D, Saranac Lj, Zivic S
Molecular and cellular biochemistry341(1-2)79-85(2010 Aug)

A proteome-wide perspective on peroxisome targeting signal 1(PTS1)-Pex5p affinities.
Ghosh D, Berg JM
Journal of the American Chemical Society132(11)3973-9(2010 Mar)

Guide molecule-driven stereospecific degradation of alpha-methylpolyamines by polyamine oxidase.
J?rvinen A, Kein?nen TA, Grigorenko NA, Khomutov AR, Uimari A, Veps?l?inen J, N?rv?nen A, Alhonen L, J?nne J
The Journal of biological chemistry281(8)4589-95(2006 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

copy number gain in the polyamine oxidase (PAOX) gene locus was accompanied by a coordinated transcriptional up-regulation in Primary myelofibrosis patients
Title: Integrative analysis of copy number and gene expression data suggests novel pathogenetic mechanisms in primary myelofibrosis.

PAO activity in children with type 1 diabetes mellitus was very high; higher blood HbA(1C) and MDA levels confirm the presence of oxidant stress demonstrate that PAO activity may participate in these circumstances
Title: Does polyamine oxidase activity influence the oxidative metabolism of children who suffer of diabetes mellitus?

polyamine oxidase degrades alpha-methylpolyamines in a stereospecific manner
Title: Guide molecule-driven stereospecific degradation of alpha-methylpolyamines by polyamine oxidase.

SSAT and SMO(PAOh1) activities are the major mediators of the cellular response of breast tumor cells to polyamines while PAO plays little or no role in this response
Title: Spermine oxidase SMO(PAOh1), Not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines.

The following PAOX gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PAOX cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu28316	NM_152911.4 Latest version!	Homo sapiens polyamine oxidase (PAOX), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu28322	NM_207128.3 Latest version!	Homo sapiens polyamine oxidase (PAOX), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$286.30 $409.00
OHu28336	NM_207127.3 Latest version!	Homo sapiens polyamine oxidase (PAOX), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$216.30 $309.00
View Old Accession Versions >>
OHu28336	NM_207127.2	Homo sapiens polyamine oxidase (PAOX), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$216.30 $309.00
OHu28322	NM_207128.2	Homo sapiens polyamine oxidase (PAOX), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$286.30 $409.00
OHu28316	NM_152911.3	Homo sapiens polyamine oxidase (PAOX), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PAOX ( NM_152911.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_690875.1 Homo sapiens polyamine oxidase (PAOX), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu28316
Clone ID Related Accession (Same CDS sequence)	NM_152911.4 , NM_152911.3
Accession Version	NM_152911.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1536bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF312698.1 and BE646315.1. On Nov 23, 2018 this sequence version replaced NM_152911.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC032778.1, SRR1163657.289408.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000278060.10/ ENSP00000278060.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGTCGA CCGGCAGCGT CGGGGAGGCC CCGGGCGGAC CCCGGGTGCT GGTGGTGGGC 
GGCGGCATCG CGGGGCTGGG CGCGGCGCAG AGGCTCTGCG GCCACTCCGC CTTCCCGCAC 
CTGCGGGTCC TGGAGGCCAC GGCCCGCGCC GGGGGCCGCA TCCGCTCGGA GCGCTGCTTC 
GGTGGCGTGG TGGAGGTGGG CGCGCACTGG ATCCATGGGC CCTCCCGGGG TAACCCCGTC 
TTCCAGCTGG CTGCTGAGTA CGGGCTGCTG GGGGAGAAGG AGCTGTCCCA GGAGAACCAG 
CTGGTGGAGA CCGGGGGTCA CGTGGGCCTG CCCTCCGTGA GCTACGCCAG CTCCGGGGCC 
AGCGTGAGCC TCCAGCTGGT GGCGGAGATG GCGACTCTGT TCTACGGCCT GATAGACCAG 
ACCCGGGAGT TCCTGCACGC TGCAGAGACC CCGGTGCCCA GCGTCGGGGA GTACCTCAAG 
AAGGAGATTG GCCAGCACGT GGCCGGCTGG ACAGAGGATG AGGAGACCAG GAAGCTGAAG 
CTGGCCGTCC TGAACTCCTT CTTCAACCTG GAATGCTGTG TGAGCGGCAC CCACAGCATG 
GACCTGGTGG CCCTGGCACC CTTTGGGGAG TATACCGTGC TGCCGGGGCT GGACTGCACC 
TTTTCTAAGG GCTATCAAGG ACTCACAAAC TGCATGATGG CCGCCCTGCC GGAGGACACT 
GTAGTTTTTG AGAAGCCTGT GAAGACCATC CACTGGAACG GGTCCTTCCA GGAGGCAGCC 
TTTCCCGGGG AGACCTTTCC AGTGTCGGTA GAGTGTGAGG ATGGAGACCG GTTCCCGGCG 
CACCATGTCA TCGTCACCGT GCCCTTAGGT TTTCTTAGGG AACATTTGGA CACCTTCTTT 
GACCCTCCCC TGCCGGCTGA GAAGGCAGAA GCAATCAGGA AGATAGGCTT TGGGACCAAC 
AACAAAATCT TCCTGGAGTT TGAGGAGCCC TTCTGGGAGC CAGACTGCCA GCTGATCCAG 
CTGGTGTGGG AGGACACGTC GCCCCTGGAG GATGCTGCCC CTGAGCTACA GGACGCCTGG 
TTCCGGAAGC TCATTGGCTT TGTGGTCCTG CCTGCCTTTG CGTCTGTCCA CGTTCTCTGT 
GGGTTCATTG CCGGACTTGA GTCTGAGTTC ATGGAGACTC TGTCGGATGA AGAAGTACTT 
CTGTGTCTCA CCCAAGTGCT CCGGAGAGTG ACAGGAAACC CACGGCTCCC CGCGCCCAAG 
AGCGTCCTGC GGTCTCGCTG GCACAGCGCC CCGTACACTA GGGGGTCCTA CAGCTACGTG 
GCCGTGGGCA GTACTGGGGG CGACCTGGAC CTGCTGGCTC AGCCCCTCCC TGCAGACGGC 
GCCGGCGCCC AGCTCCAGAT CCTGTTTGCG GGGGAAGCCA CACATCGCAC GTTTTACTCC 
ACGACGCACG GGGCTCTGCT GTCGGGATGG AGGGAGGCCG ACCGCCTCCT CAGTCTGTGG 
GCCCCGCAGG TGCAGCAGCC CAGGCCCAGG CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_690875.1
CDS	56..1591
Translation	MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGASVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLKLAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDTVVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFFDPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQDAWFRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVLRRVTGNPRLPAPKSVLRSRWHSAPYTRGSYSYVAVGSTGGDLDLLAQPLPADGAGAQLQILFAGEATHRTFYSTTHGALLSGWREADRLLSLWAPQVQQPRPRL

Target ORF information:

RefSeq Version	NM_152911.4
Organism	Homo sapiens(human)
Definition	Homo sapiens polyamine oxidase (PAOX), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152911.4

ORF Insert Sequence:

ATGGAGTCGA CCGGCAGCGT CGGGGAGGCC CCGGGCGGAC CCCGGGTGCT GGTGGTGGGC 
GGCGGCATCG CGGGGCTGGG CGCGGCGCAG AGGCTCTGCG GCCACTCCGC CTTCCCGCAC 
CTGCGGGTCC TGGAGGCCAC GGCCCGCGCC GGGGGCCGCA TCCGCTCGGA GCGCTGCTTC 
GGTGGCGTGG TGGAGGTGGG CGCGCACTGG ATCCATGGGC CCTCCCGGGG TAACCCCGTC 
TTCCAGCTGG CTGCTGAGTA CGGGCTGCTG GGGGAGAAGG AGCTGTCCCA GGAGAACCAG 
CTGGTGGAGA CCGGGGGTCA CGTGGGCCTG CCCTCCGTGA GCTACGCCAG CTCCGGGGCC 
AGCGTGAGCC TCCAGCTGGT GGCGGAGATG GCGACTCTGT TCTACGGCCT GATAGACCAG 
ACCCGGGAGT TCCTGCACGC TGCAGAGACC CCGGTGCCCA GCGTCGGGGA GTACCTCAAG 
AAGGAGATTG GCCAGCACGT GGCCGGCTGG ACAGAGGATG AGGAGACCAG GAAGCTGAAG 
CTGGCCGTCC TGAACTCCTT CTTCAACCTG GAATGCTGTG TGAGCGGCAC CCACAGCATG 
GACCTGGTGG CCCTGGCACC CTTTGGGGAG TATACCGTGC TGCCGGGGCT GGACTGCACC 
TTTTCTAAGG GCTATCAAGG ACTCACAAAC TGCATGATGG CCGCCCTGCC GGAGGACACT 
GTAGTTTTTG AGAAGCCTGT GAAGACCATC CACTGGAACG GGTCCTTCCA GGAGGCAGCC 
TTTCCCGGGG AGACCTTTCC AGTGTCGGTA GAGTGTGAGG ATGGAGACCG GTTCCCGGCG 
CACCATGTCA TCGTCACCGT GCCCTTAGGT TTTCTTAGGG AACATTTGGA CACCTTCTTT 
GACCCTCCCC TGCCGGCTGA GAAGGCAGAA GCAATCAGGA AGATAGGCTT TGGGACCAAC 
AACAAAATCT TCCTGGAGTT TGAGGAGCCC TTCTGGGAGC CAGACTGCCA GCTGATCCAG 
CTGGTGTGGG AGGACACGTC GCCCCTGGAG GATGCTGCCC CTGAGCTACA GGACGCCTGG 
TTCCGGAAGC TCATTGGCTT TGTGGTCCTG CCTGCCTTTG CGTCTGTCCA CGTTCTCTGT 
GGGTTCATTG CCGGACTTGA GTCTGAGTTC ATGGAGACTC TGTCGGATGA AGAAGTACTT 
CTGTGTCTCA CCCAAGTGCT CCGGAGAGTG ACAGGAAACC CACGGCTCCC CGCGCCCAAG 
AGCGTCCTGC GGTCTCGCTG GCACAGCGCC CCGTACACTA GGGGGTCCTA CAGCTACGTG 
GCCGTGGGCA GTACTGGGGG CGACCTGGAC CTGCTGGCTC AGCCCCTCCC TGCAGACGGC 
GCCGGCGCCC AGCTCCAGAT CCTGTTTGCG GGGGAAGCCA CACATCGCAC GTTTTACTCC 
ACGACGCACG GGGCTCTGCT GTCGGGATGG AGGGAGGCCG ACCGCCTCCT CAGTCTGTGG 
GCCCCGCAGG TGCAGCAGCC CAGGCCCAGG CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAOX ( NM_152911.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_690875.1 Homo sapiens polyamine oxidase (PAOX), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu28316
Clone ID Related Accession (Same CDS sequence)	NM_152911.4 , NM_152911.3
Accession Version	NM_152911.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1536bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-06-25
Organism	Homo sapiens(human)
Product	peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC032778.1, AF312698.1, BE646315.1 and AA280165.1. On Dec 10, 2013 this sequence version replaced NM_152911.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC032778.1, AF312698.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGGAGTCGA CCGGCAGCGT CGGGGAGGCC CCGGGCGGAC CCCGGGTGCT GGTGGTGGGC 
GGCGGCATCG CGGGGCTGGG CGCGGCGCAG AGGCTCTGCG GCCACTCCGC CTTCCCGCAC 
CTGCGGGTCC TGGAGGCCAC GGCCCGCGCC GGGGGCCGCA TCCGCTCGGA GCGCTGCTTC 
GGTGGCGTGG TGGAGGTGGG CGCGCACTGG ATCCATGGGC CCTCCCGGGG TAACCCCGTC 
TTCCAGCTGG CTGCTGAGTA CGGGCTGCTG GGGGAGAAGG AGCTGTCCCA GGAGAACCAG 
CTGGTGGAGA CCGGGGGTCA CGTGGGCCTG CCCTCCGTGA GCTACGCCAG CTCCGGGGCC 
AGCGTGAGCC TCCAGCTGGT GGCGGAGATG GCGACTCTGT TCTACGGCCT GATAGACCAG 
ACCCGGGAGT TCCTGCACGC TGCAGAGACC CCGGTGCCCA GCGTCGGGGA GTACCTCAAG 
AAGGAGATTG GCCAGCACGT GGCCGGCTGG ACAGAGGATG AGGAGACCAG GAAGCTGAAG 
CTGGCCGTCC TGAACTCCTT CTTCAACCTG GAATGCTGTG TGAGCGGCAC CCACAGCATG 
GACCTGGTGG CCCTGGCACC CTTTGGGGAG TATACCGTGC TGCCGGGGCT GGACTGCACC 
TTTTCTAAGG GCTATCAAGG ACTCACAAAC TGCATGATGG CCGCCCTGCC GGAGGACACT 
GTAGTTTTTG AGAAGCCTGT GAAGACCATC CACTGGAACG GGTCCTTCCA GGAGGCAGCC 
TTTCCCGGGG AGACCTTTCC AGTGTCGGTA GAGTGTGAGG ATGGAGACCG GTTCCCGGCG 
CACCATGTCA TCGTCACCGT GCCCTTAGGT TTTCTTAGGG AACATTTGGA CACCTTCTTT 
GACCCTCCCC TGCCGGCTGA GAAGGCAGAA GCAATCAGGA AGATAGGCTT TGGGACCAAC 
AACAAAATCT TCCTGGAGTT TGAGGAGCCC TTCTGGGAGC CAGACTGCCA GCTGATCCAG 
CTGGTGTGGG AGGACACGTC GCCCCTGGAG GATGCTGCCC CTGAGCTACA GGACGCCTGG 
TTCCGGAAGC TCATTGGCTT TGTGGTCCTG CCTGCCTTTG CGTCTGTCCA CGTTCTCTGT 
GGGTTCATTG CCGGACTTGA GTCTGAGTTC ATGGAGACTC TGTCGGATGA AGAAGTACTT 
CTGTGTCTCA CCCAAGTGCT CCGGAGAGTG ACAGGAAACC CACGGCTCCC CGCGCCCAAG 
AGCGTCCTGC GGTCTCGCTG GCACAGCGCC CCGTACACTA GGGGGTCCTA CAGCTACGTG 
GCCGTGGGCA GTACTGGGGG CGACCTGGAC CTGCTGGCTC AGCCCCTCCC TGCAGACGGC 
GCCGGCGCCC AGCTCCAGAT CCTGTTTGCG GGGGAAGCCA CACATCGCAC GTTTTACTCC 
ACGACGCACG GGGCTCTGCT GTCGGGATGG AGGGAGGCCG ACCGCCTCCT CAGTCTGTGG 
GCCCCGCAGG TGCAGCAGCC CAGGCCCAGG CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_690875.1
CDS	81..1616
Translation	MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGASVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLKLAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDTVVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFFDPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQDAWFRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVLRRVTGNPRLPAPKSVLRSRWHSAPYTRGSYSYVAVGSTGGDLDLLAQPLPADGAGAQLQILFAGEATHRTFYSTTHGALLSGWREADRLLSLWAPQVQQPRPRL

Target ORF information:

RefSeq Version	NM_152911.3
Organism	Homo sapiens(human)
Definition	Homo sapiens polyamine oxidase (PAOX), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_152911.3

ORF Insert Sequence:

ATGGAGTCGA CCGGCAGCGT CGGGGAGGCC CCGGGCGGAC CCCGGGTGCT GGTGGTGGGC 
GGCGGCATCG CGGGGCTGGG CGCGGCGCAG AGGCTCTGCG GCCACTCCGC CTTCCCGCAC 
CTGCGGGTCC TGGAGGCCAC GGCCCGCGCC GGGGGCCGCA TCCGCTCGGA GCGCTGCTTC 
GGTGGCGTGG TGGAGGTGGG CGCGCACTGG ATCCATGGGC CCTCCCGGGG TAACCCCGTC 
TTCCAGCTGG CTGCTGAGTA CGGGCTGCTG GGGGAGAAGG AGCTGTCCCA GGAGAACCAG 
CTGGTGGAGA CCGGGGGTCA CGTGGGCCTG CCCTCCGTGA GCTACGCCAG CTCCGGGGCC 
AGCGTGAGCC TCCAGCTGGT GGCGGAGATG GCGACTCTGT TCTACGGCCT GATAGACCAG 
ACCCGGGAGT TCCTGCACGC TGCAGAGACC CCGGTGCCCA GCGTCGGGGA GTACCTCAAG 
AAGGAGATTG GCCAGCACGT GGCCGGCTGG ACAGAGGATG AGGAGACCAG GAAGCTGAAG 
CTGGCCGTCC TGAACTCCTT CTTCAACCTG GAATGCTGTG TGAGCGGCAC CCACAGCATG 
GACCTGGTGG CCCTGGCACC CTTTGGGGAG TATACCGTGC TGCCGGGGCT GGACTGCACC 
TTTTCTAAGG GCTATCAAGG ACTCACAAAC TGCATGATGG CCGCCCTGCC GGAGGACACT 
GTAGTTTTTG AGAAGCCTGT GAAGACCATC CACTGGAACG GGTCCTTCCA GGAGGCAGCC 
TTTCCCGGGG AGACCTTTCC AGTGTCGGTA GAGTGTGAGG ATGGAGACCG GTTCCCGGCG 
CACCATGTCA TCGTCACCGT GCCCTTAGGT TTTCTTAGGG AACATTTGGA CACCTTCTTT 
GACCCTCCCC TGCCGGCTGA GAAGGCAGAA GCAATCAGGA AGATAGGCTT TGGGACCAAC 
AACAAAATCT TCCTGGAGTT TGAGGAGCCC TTCTGGGAGC CAGACTGCCA GCTGATCCAG 
CTGGTGTGGG AGGACACGTC GCCCCTGGAG GATGCTGCCC CTGAGCTACA GGACGCCTGG 
TTCCGGAAGC TCATTGGCTT TGTGGTCCTG CCTGCCTTTG CGTCTGTCCA CGTTCTCTGT 
GGGTTCATTG CCGGACTTGA GTCTGAGTTC ATGGAGACTC TGTCGGATGA AGAAGTACTT 
CTGTGTCTCA CCCAAGTGCT CCGGAGAGTG ACAGGAAACC CACGGCTCCC CGCGCCCAAG 
AGCGTCCTGC GGTCTCGCTG GCACAGCGCC CCGTACACTA GGGGGTCCTA CAGCTACGTG 
GCCGTGGGCA GTACTGGGGG CGACCTGGAC CTGCTGGCTC AGCCCCTCCC TGCAGACGGC 
GCCGGCGCCC AGCTCCAGAT CCTGTTTGCG GGGGAAGCCA CACATCGCAC GTTTTACTCC 
ACGACGCACG GGGCTCTGCT GTCGGGATGG AGGGAGGCCG ACCGCCTCCT CAGTCTGTGG 
GCCCCGCAGG TGCAGCAGCC CAGGCCCAGG CTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAOX ( NM_207128.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_997011.1 Homo sapiens polyamine oxidase (PAOX), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu28322
Clone ID Related Accession (Same CDS sequence)	NM_207128.3 , NM_207128.2
Accession Version	NM_207128.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1461bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-30
Organism	Homo sapiens(human)
Product	peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF312698.1 and BE646315.1. On May 31, 2019 this sequence version replaced NM_207128.2. Transcript Variant: This variant (5) lacks an alternate exon in the 3' coding region, resulting in a frameshift, compared to variant 1. It encodes isoform 4, which is shorter and has a distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AY541516.1, SRR3476690.1068560.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGGAGTCGA CCGGCAGCGT CGGGGAGGCC CCGGGCGGAC CCCGGGTGCT GGTGGTGGGC 
GGCGGCATCG CGGGGCTGGG CGCGGCGCAG AGGCTCTGCG GCCACTCCGC CTTCCCGCAC 
CTGCGGGTCC TGGAGGCCAC GGCCCGCGCC GGGGGCCGCA TCCGCTCGGA GCGCTGCTTC 
GGTGGCGTGG TGGAGGTGGG CGCGCACTGG ATCCATGGGC CCTCCCGGGG TAACCCCGTC 
TTCCAGCTGG CTGCTGAGTA CGGGCTGCTG GGGGAGAAGG AGCTGTCCCA GGAGAACCAG 
CTGGTGGAGA CCGGGGGTCA CGTGGGCCTG CCCTCCGTGA GCTACGCCAG CTCCGGGGCC 
AGCGTGAGCC TCCAGCTGGT GGCGGAGATG GCGACTCTGT TCTACGGCCT GATAGACCAG 
ACCCGGGAGT TCCTGCACGC TGCAGAGACC CCGGTGCCCA GCGTCGGGGA GTACCTCAAG 
AAGGAGATTG GCCAGCACGT GGCCGGCTGG ACAGAGGATG AGGAGACCAG GAAGCTGAAG 
CTGGCCGTCC TGAACTCCTT CTTCAACCTG GAATGCTGTG TGAGCGGCAC CCACAGCATG 
GACCTGGTGG CCCTGGCACC CTTTGGGGAG TATACCGTGC TGCCGGGGCT GGACTGCACC 
TTTTCTAAGG GCTATCAAGG ACTCACAAAC TGCATGATGG CCGCCCTGCC GGAGGACACT 
GTAGTTTTTG AGAAGCCTGT GAAGACCATC CACTGGAACG GGTCCTTCCA GGAGGCAGCC 
TTTCCCGGGG AGACCTTTCC AGTGTCGGTA GAGTGTGAGG ATGGAGACCG GTTCCCGGCG 
CACCATGTCA TCGTCACCGT GCCCTTAGGT TTTCTTAGGG AACATTTGGA CACCTTCTTT 
GACCCTCCCC TGCCGGCTGA GAAGGCAGAA GCAATCAGGA AGATAGGCTT TGGGACCAAC 
AACAAAATCT TCCTGGAGTT TGAGGAGCCC TTCTGGGAGC CAGACTGCCA GCTGATCCAG 
CTGGTGTGGG AGGACACGTC GCCCCTGGAG GATGCTGCCC CTGAGCTACA GGACGCCTGG 
TTCCGGAAGC TCATTGGCTT TGTGGTCCTG CCTGCCTTTG CGTCTGTCCA CGTTCTCTGT 
GGGTTCATTG CCGGACTTGA GTCTGAGTTC ATGGAGACTC TGTCGGATGA AGAAGTACTT 
CTGTGTCTCA CCCAAGTGCT CCGGAGAGTG ACAGCTCCAG ATCCTGTTTG CGGGGGAAGC 
CACACATCGC ACGTTTTACT CCACGACGCA CGGGGCTCTG CTGTCGGGAT GGAGGGAGGC 
CGACCGCCTC CTCAGTCTGT GGGCCCCGCA GGTGCAGCAG CCCAGGCCCA GGCTCTAGCT 
GGGCCCAGCC TACTCTGTTC CACCCGTGTC GGGGGTAGGC TGGGACCCTC ATTTCTTCTG 
ACAGATTTCA GTCTGGCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997011.1
CDS	56..1516
Translation	MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGASVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLKLAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDTVVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFFDPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQDAWFRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVLRRVTAPDPVCGGSHTSHVLLHDARGSAVGMEGGRPPPQSVGPAGAAAQAQALAGPSLLCSTRVGGRLGPSFLLTDFSLA

Target ORF information:

RefSeq Version	NM_207128.3
Organism	Homo sapiens(human)
Definition	Homo sapiens polyamine oxidase (PAOX), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_207128.3

ORF Insert Sequence:

ATGGAGTCGA CCGGCAGCGT CGGGGAGGCC CCGGGCGGAC CCCGGGTGCT GGTGGTGGGC 
GGCGGCATCG CGGGGCTGGG CGCGGCGCAG AGGCTCTGCG GCCACTCCGC CTTCCCGCAC 
CTGCGGGTCC TGGAGGCCAC GGCCCGCGCC GGGGGCCGCA TCCGCTCGGA GCGCTGCTTC 
GGTGGCGTGG TGGAGGTGGG CGCGCACTGG ATCCATGGGC CCTCCCGGGG TAACCCCGTC 
TTCCAGCTGG CTGCTGAGTA CGGGCTGCTG GGGGAGAAGG AGCTGTCCCA GGAGAACCAG 
CTGGTGGAGA CCGGGGGTCA CGTGGGCCTG CCCTCCGTGA GCTACGCCAG CTCCGGGGCC 
AGCGTGAGCC TCCAGCTGGT GGCGGAGATG GCGACTCTGT TCTACGGCCT GATAGACCAG 
ACCCGGGAGT TCCTGCACGC TGCAGAGACC CCGGTGCCCA GCGTCGGGGA GTACCTCAAG 
AAGGAGATTG GCCAGCACGT GGCCGGCTGG ACAGAGGATG AGGAGACCAG GAAGCTGAAG 
CTGGCCGTCC TGAACTCCTT CTTCAACCTG GAATGCTGTG TGAGCGGCAC CCACAGCATG 
GACCTGGTGG CCCTGGCACC CTTTGGGGAG TATACCGTGC TGCCGGGGCT GGACTGCACC 
TTTTCTAAGG GCTATCAAGG ACTCACAAAC TGCATGATGG CCGCCCTGCC GGAGGACACT 
GTAGTTTTTG AGAAGCCTGT GAAGACCATC CACTGGAACG GGTCCTTCCA GGAGGCAGCC 
TTTCCCGGGG AGACCTTTCC AGTGTCGGTA GAGTGTGAGG ATGGAGACCG GTTCCCGGCG 
CACCATGTCA TCGTCACCGT GCCCTTAGGT TTTCTTAGGG AACATTTGGA CACCTTCTTT 
GACCCTCCCC TGCCGGCTGA GAAGGCAGAA GCAATCAGGA AGATAGGCTT TGGGACCAAC 
AACAAAATCT TCCTGGAGTT TGAGGAGCCC TTCTGGGAGC CAGACTGCCA GCTGATCCAG 
CTGGTGTGGG AGGACACGTC GCCCCTGGAG GATGCTGCCC CTGAGCTACA GGACGCCTGG 
TTCCGGAAGC TCATTGGCTT TGTGGTCCTG CCTGCCTTTG CGTCTGTCCA CGTTCTCTGT 
GGGTTCATTG CCGGACTTGA GTCTGAGTTC ATGGAGACTC TGTCGGATGA AGAAGTACTT 
CTGTGTCTCA CCCAAGTGCT CCGGAGAGTG ACAGCTCCAG ATCCTGTTTG CGGGGGAAGC 
CACACATCGC ACGTTTTACT CCACGACGCA CGGGGCTCTG CTGTCGGGAT GGAGGGAGGC 
CGACCGCCTC CTCAGTCTGT GGGCCCCGCA GGTGCAGCAG CCCAGGCCCA GGCTCTAGCT 
GGGCCCAGCC TACTCTGTTC CACCCGTGTC GGGGGTAGGC TGGGACCCTC ATTTCTTCTG 
ACAGATTTCA GTCTGGCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAOX ( NM_207128.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_997011.1 Homo sapiens polyamine oxidase (PAOX), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu28322
Clone ID Related Accession (Same CDS sequence)	NM_207128.3 , NM_207128.2
Accession Version	NM_207128.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1461bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-05
Organism	Homo sapiens(human)
Product	peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC032778.1, AF312698.1, BE646315.1 and AA280165.1. On Dec 10, 2013 this sequence version replaced NM_207128.1. Transcript Variant: This variant (5) lacks an alternate exon in the 3' coding region, resulting in a frameshift, compared to variant 1. It encodes isoform 4, which is shorter and has a distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AY541516.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGGAGTCGA CCGGCAGCGT CGGGGAGGCC CCGGGCGGAC CCCGGGTGCT GGTGGTGGGC 
GGCGGCATCG CGGGGCTGGG CGCGGCGCAG AGGCTCTGCG GCCACTCCGC CTTCCCGCAC 
CTGCGGGTCC TGGAGGCCAC GGCCCGCGCC GGGGGCCGCA TCCGCTCGGA GCGCTGCTTC 
GGTGGCGTGG TGGAGGTGGG CGCGCACTGG ATCCATGGGC CCTCCCGGGG TAACCCCGTC 
TTCCAGCTGG CTGCTGAGTA CGGGCTGCTG GGGGAGAAGG AGCTGTCCCA GGAGAACCAG 
CTGGTGGAGA CCGGGGGTCA CGTGGGCCTG CCCTCCGTGA GCTACGCCAG CTCCGGGGCC 
AGCGTGAGCC TCCAGCTGGT GGCGGAGATG GCGACTCTGT TCTACGGCCT GATAGACCAG 
ACCCGGGAGT TCCTGCACGC TGCAGAGACC CCGGTGCCCA GCGTCGGGGA GTACCTCAAG 
AAGGAGATTG GCCAGCACGT GGCCGGCTGG ACAGAGGATG AGGAGACCAG GAAGCTGAAG 
CTGGCCGTCC TGAACTCCTT CTTCAACCTG GAATGCTGTG TGAGCGGCAC CCACAGCATG 
GACCTGGTGG CCCTGGCACC CTTTGGGGAG TATACCGTGC TGCCGGGGCT GGACTGCACC 
TTTTCTAAGG GCTATCAAGG ACTCACAAAC TGCATGATGG CCGCCCTGCC GGAGGACACT 
GTAGTTTTTG AGAAGCCTGT GAAGACCATC CACTGGAACG GGTCCTTCCA GGAGGCAGCC 
TTTCCCGGGG AGACCTTTCC AGTGTCGGTA GAGTGTGAGG ATGGAGACCG GTTCCCGGCG 
CACCATGTCA TCGTCACCGT GCCCTTAGGT TTTCTTAGGG AACATTTGGA CACCTTCTTT 
GACCCTCCCC TGCCGGCTGA GAAGGCAGAA GCAATCAGGA AGATAGGCTT TGGGACCAAC 
AACAAAATCT TCCTGGAGTT TGAGGAGCCC TTCTGGGAGC CAGACTGCCA GCTGATCCAG 
CTGGTGTGGG AGGACACGTC GCCCCTGGAG GATGCTGCCC CTGAGCTACA GGACGCCTGG 
TTCCGGAAGC TCATTGGCTT TGTGGTCCTG CCTGCCTTTG CGTCTGTCCA CGTTCTCTGT 
GGGTTCATTG CCGGACTTGA GTCTGAGTTC ATGGAGACTC TGTCGGATGA AGAAGTACTT 
CTGTGTCTCA CCCAAGTGCT CCGGAGAGTG ACAGCTCCAG ATCCTGTTTG CGGGGGAAGC 
CACACATCGC ACGTTTTACT CCACGACGCA CGGGGCTCTG CTGTCGGGAT GGAGGGAGGC 
CGACCGCCTC CTCAGTCTGT GGGCCCCGCA GGTGCAGCAG CCCAGGCCCA GGCTCTAGCT 
GGGCCCAGCC TACTCTGTTC CACCCGTGTC GGGGGTAGGC TGGGACCCTC ATTTCTTCTG 
ACAGATTTCA GTCTGGCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997011.1
CDS	81..1541
Translation	MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGASVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLKLAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDTVVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFFDPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQDAWFRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVLRRVTAPDPVCGGSHTSHVLLHDARGSAVGMEGGRPPPQSVGPAGAAAQAQALAGPSLLCSTRVGGRLGPSFLLTDFSLA

Target ORF information:

RefSeq Version	NM_207128.2
Organism	Homo sapiens(human)
Definition	Homo sapiens polyamine oxidase (PAOX), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_207128.2

ORF Insert Sequence:

ATGGAGTCGA CCGGCAGCGT CGGGGAGGCC CCGGGCGGAC CCCGGGTGCT GGTGGTGGGC 
GGCGGCATCG CGGGGCTGGG CGCGGCGCAG AGGCTCTGCG GCCACTCCGC CTTCCCGCAC 
CTGCGGGTCC TGGAGGCCAC GGCCCGCGCC GGGGGCCGCA TCCGCTCGGA GCGCTGCTTC 
GGTGGCGTGG TGGAGGTGGG CGCGCACTGG ATCCATGGGC CCTCCCGGGG TAACCCCGTC 
TTCCAGCTGG CTGCTGAGTA CGGGCTGCTG GGGGAGAAGG AGCTGTCCCA GGAGAACCAG 
CTGGTGGAGA CCGGGGGTCA CGTGGGCCTG CCCTCCGTGA GCTACGCCAG CTCCGGGGCC 
AGCGTGAGCC TCCAGCTGGT GGCGGAGATG GCGACTCTGT TCTACGGCCT GATAGACCAG 
ACCCGGGAGT TCCTGCACGC TGCAGAGACC CCGGTGCCCA GCGTCGGGGA GTACCTCAAG 
AAGGAGATTG GCCAGCACGT GGCCGGCTGG ACAGAGGATG AGGAGACCAG GAAGCTGAAG 
CTGGCCGTCC TGAACTCCTT CTTCAACCTG GAATGCTGTG TGAGCGGCAC CCACAGCATG 
GACCTGGTGG CCCTGGCACC CTTTGGGGAG TATACCGTGC TGCCGGGGCT GGACTGCACC 
TTTTCTAAGG GCTATCAAGG ACTCACAAAC TGCATGATGG CCGCCCTGCC GGAGGACACT 
GTAGTTTTTG AGAAGCCTGT GAAGACCATC CACTGGAACG GGTCCTTCCA GGAGGCAGCC 
TTTCCCGGGG AGACCTTTCC AGTGTCGGTA GAGTGTGAGG ATGGAGACCG GTTCCCGGCG 
CACCATGTCA TCGTCACCGT GCCCTTAGGT TTTCTTAGGG AACATTTGGA CACCTTCTTT 
GACCCTCCCC TGCCGGCTGA GAAGGCAGAA GCAATCAGGA AGATAGGCTT TGGGACCAAC 
AACAAAATCT TCCTGGAGTT TGAGGAGCCC TTCTGGGAGC CAGACTGCCA GCTGATCCAG 
CTGGTGTGGG AGGACACGTC GCCCCTGGAG GATGCTGCCC CTGAGCTACA GGACGCCTGG 
TTCCGGAAGC TCATTGGCTT TGTGGTCCTG CCTGCCTTTG CGTCTGTCCA CGTTCTCTGT 
GGGTTCATTG CCGGACTTGA GTCTGAGTTC ATGGAGACTC TGTCGGATGA AGAAGTACTT 
CTGTGTCTCA CCCAAGTGCT CCGGAGAGTG ACAGCTCCAG ATCCTGTTTG CGGGGGAAGC 
CACACATCGC ACGTTTTACT CCACGACGCA CGGGGCTCTG CTGTCGGGAT GGAGGGAGGC 
CGACCGCCTC CTCAGTCTGT GGGCCCCGCA GGTGCAGCAG CCCAGGCCCA GGCTCTAGCT 
GGGCCCAGCC TACTCTGTTC CACCCGTGTC GGGGGTAGGC TGGGACCCTC ATTTCTTCTG 
ACAGATTTCA GTCTGGCTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAOX ( NM_207127.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_997010.1 Homo sapiens polyamine oxidase (PAOX), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu28336
Clone ID Related Accession (Same CDS sequence)	NM_207127.2 , NM_207127.3
Accession Version	NM_207127.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-05
Organism	Homo sapiens(human)
Product	peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC032778.1, AF312698.1, AY541514.1, AY541519.1 and AA280165.1. On Dec 10, 2013 this sequence version replaced NM_207127.1. Transcript Variant: This variant (4) lacks two exons in the 3' coding region, resulting in a frameshift and an early stop codon, compared to variant 1. It encodes isoform 2, which is shorter and has a distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AY541515.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

ATGGAGTCGA CCGGCAGCGT CGGGGAGGCC CCGGGCGGAC CCCGGGTGCT GGTGGTGGGC 
GGCGGCATCG CGGGGCTGGG CGCGGCGCAG AGGCTCTGCG GCCACTCCGC CTTCCCGCAC 
CTGCGGGTCC TGGAGGCCAC GGCCCGCGCC GGGGGCCGCA TCCGCTCGGA GCGCTGCTTC 
GGTGGCGTGG TGGAGGTGGG CGCGCACTGG ATCCATGGGC CCTCCCGGGG TAACCCCGTC 
TTCCAGCTGG CTGCTGAGTA CGGGCTGCTG GGGGAGAAGG AGCTGTCCCA GGAGAACCAG 
CTGGTGGAGA CCGGGGGTCA CGTGGGCCTG CCCTCCGTGA GCTACGCCAG CTCCGGGGCC 
AGCGTGAGCC TCCAGCTGGT GGCGGAGATG GCGACTCTGT TCTACGGCCT GATAGACCAG 
ACCCGGGAGT TCCTGCACGC TGCAGAGACC CCGGTGCCCA GCGTCGGGGA GTACCTCAAG 
AAGGAGATTG GCCAGCACGT GGCCGGCTGG ACAGAGGATG AGGAGACCAG GAAGCTGAAG 
CTGGCCGTCC TGAACTCCTT CTTCAACCTG GAATGCTGTG TGAGCGGCAC CCACAGCATG 
GACCTGGTGG CCCTGGCACC CTTTGGGGAG TATACCGTGC TGCCGGGGCT GGACTGCACC 
TTTTCTAAGG GCTATCAAGG ACTCACAAAC TGCATGATGG CCGCCCTGCC GGAGGACACT 
GTAGTTTTTG AGAAGCCTGT GAAGACCATC CACTGGAACG GGTCCTTCCA GGAGGCAGCC 
TTTCCCGGGG AGACCTTTCC AGTGTCGGTA GAGTGTGAGG ATGGAGACCG GTTCCCGGCG 
CACCATGTCA TCGTCACCGT GCCCTTAGGT CTGTCCACGT TCTCTGTGGG TTCATTGCCG 
GACTTGAGTC TGAGTTCATG GAGACTCTGT CGGATGAAGA AGTACTTCTG TGTCTCACCC 
AAGTGCTCCG GAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997010.1
CDS	81..1058
Translation	MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGASVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLKLAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDTVVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGLSTFSVGSLPDLSLSSWRLCRMKKYFCVSPKCSGE

Target ORF information:

RefSeq Version	NM_207127.2
Organism	Homo sapiens(human)
Definition	Homo sapiens polyamine oxidase (PAOX), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_207127.2

ORF Insert Sequence:

ATGGAGTCGA CCGGCAGCGT CGGGGAGGCC CCGGGCGGAC CCCGGGTGCT GGTGGTGGGC 
GGCGGCATCG CGGGGCTGGG CGCGGCGCAG AGGCTCTGCG GCCACTCCGC CTTCCCGCAC 
CTGCGGGTCC TGGAGGCCAC GGCCCGCGCC GGGGGCCGCA TCCGCTCGGA GCGCTGCTTC 
GGTGGCGTGG TGGAGGTGGG CGCGCACTGG ATCCATGGGC CCTCCCGGGG TAACCCCGTC 
TTCCAGCTGG CTGCTGAGTA CGGGCTGCTG GGGGAGAAGG AGCTGTCCCA GGAGAACCAG 
CTGGTGGAGA CCGGGGGTCA CGTGGGCCTG CCCTCCGTGA GCTACGCCAG CTCCGGGGCC 
AGCGTGAGCC TCCAGCTGGT GGCGGAGATG GCGACTCTGT TCTACGGCCT GATAGACCAG 
ACCCGGGAGT TCCTGCACGC TGCAGAGACC CCGGTGCCCA GCGTCGGGGA GTACCTCAAG 
AAGGAGATTG GCCAGCACGT GGCCGGCTGG ACAGAGGATG AGGAGACCAG GAAGCTGAAG 
CTGGCCGTCC TGAACTCCTT CTTCAACCTG GAATGCTGTG TGAGCGGCAC CCACAGCATG 
GACCTGGTGG CCCTGGCACC CTTTGGGGAG TATACCGTGC TGCCGGGGCT GGACTGCACC 
TTTTCTAAGG GCTATCAAGG ACTCACAAAC TGCATGATGG CCGCCCTGCC GGAGGACACT 
GTAGTTTTTG AGAAGCCTGT GAAGACCATC CACTGGAACG GGTCCTTCCA GGAGGCAGCC 
TTTCCCGGGG AGACCTTTCC AGTGTCGGTA GAGTGTGAGG ATGGAGACCG GTTCCCGGCG 
CACCATGTCA TCGTCACCGT GCCCTTAGGT CTGTCCACGT TCTCTGTGGG TTCATTGCCG 
GACTTGAGTC TGAGTTCATG GAGACTCTGT CGGATGAAGA AGTACTTCTG TGTCTCACCC 
AAGTGCTCCG GAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PAOX ( NM_207127.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_997010.1 Homo sapiens polyamine oxidase (PAOX), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu28336
Clone ID Related Accession (Same CDS sequence)	NM_207127.2 , NM_207127.3
Accession Version	NM_207127.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-30
Organism	Homo sapiens(human)
Product	peroxisomal N(1)-acetyl-spermine/spermidine oxidase isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF312698.1, AY541514.1, AY541519.1 and AA280165.1. On May 31, 2019 this sequence version replaced NM_207127.2. Transcript Variant: This variant (4) lacks two exons in the 3' coding region, resulting in a frameshift and an early stop codon, compared to variant 1. It encodes isoform 2, which is shorter and has a distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AY541515.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

ATGGAGTCGA CCGGCAGCGT CGGGGAGGCC CCGGGCGGAC CCCGGGTGCT GGTGGTGGGC 
GGCGGCATCG CGGGGCTGGG CGCGGCGCAG AGGCTCTGCG GCCACTCCGC CTTCCCGCAC 
CTGCGGGTCC TGGAGGCCAC GGCCCGCGCC GGGGGCCGCA TCCGCTCGGA GCGCTGCTTC 
GGTGGCGTGG TGGAGGTGGG CGCGCACTGG ATCCATGGGC CCTCCCGGGG TAACCCCGTC 
TTCCAGCTGG CTGCTGAGTA CGGGCTGCTG GGGGAGAAGG AGCTGTCCCA GGAGAACCAG 
CTGGTGGAGA CCGGGGGTCA CGTGGGCCTG CCCTCCGTGA GCTACGCCAG CTCCGGGGCC 
AGCGTGAGCC TCCAGCTGGT GGCGGAGATG GCGACTCTGT TCTACGGCCT GATAGACCAG 
ACCCGGGAGT TCCTGCACGC TGCAGAGACC CCGGTGCCCA GCGTCGGGGA GTACCTCAAG 
AAGGAGATTG GCCAGCACGT GGCCGGCTGG ACAGAGGATG AGGAGACCAG GAAGCTGAAG 
CTGGCCGTCC TGAACTCCTT CTTCAACCTG GAATGCTGTG TGAGCGGCAC CCACAGCATG 
GACCTGGTGG CCCTGGCACC CTTTGGGGAG TATACCGTGC TGCCGGGGCT GGACTGCACC 
TTTTCTAAGG GCTATCAAGG ACTCACAAAC TGCATGATGG CCGCCCTGCC GGAGGACACT 
GTAGTTTTTG AGAAGCCTGT GAAGACCATC CACTGGAACG GGTCCTTCCA GGAGGCAGCC 
TTTCCCGGGG AGACCTTTCC AGTGTCGGTA GAGTGTGAGG ATGGAGACCG GTTCCCGGCG 
CACCATGTCA TCGTCACCGT GCCCTTAGGT CTGTCCACGT TCTCTGTGGG TTCATTGCCG 
GACTTGAGTC TGAGTTCATG GAGACTCTGT CGGATGAAGA AGTACTTCTG TGTCTCACCC 
AAGTGCTCCG GAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997010.1
CDS	56..1033
Translation	MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGASVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLKLAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDTVVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGLSTFSVGSLPDLSLSSWRLCRMKKYFCVSPKCSGE

Target ORF information:

RefSeq Version	NM_207127.3
Organism	Homo sapiens(human)
Definition	Homo sapiens polyamine oxidase (PAOX), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_207127.3

ORF Insert Sequence:

ATGGAGTCGA CCGGCAGCGT CGGGGAGGCC CCGGGCGGAC CCCGGGTGCT GGTGGTGGGC 
GGCGGCATCG CGGGGCTGGG CGCGGCGCAG AGGCTCTGCG GCCACTCCGC CTTCCCGCAC 
CTGCGGGTCC TGGAGGCCAC GGCCCGCGCC GGGGGCCGCA TCCGCTCGGA GCGCTGCTTC 
GGTGGCGTGG TGGAGGTGGG CGCGCACTGG ATCCATGGGC CCTCCCGGGG TAACCCCGTC 
TTCCAGCTGG CTGCTGAGTA CGGGCTGCTG GGGGAGAAGG AGCTGTCCCA GGAGAACCAG 
CTGGTGGAGA CCGGGGGTCA CGTGGGCCTG CCCTCCGTGA GCTACGCCAG CTCCGGGGCC 
AGCGTGAGCC TCCAGCTGGT GGCGGAGATG GCGACTCTGT TCTACGGCCT GATAGACCAG 
ACCCGGGAGT TCCTGCACGC TGCAGAGACC CCGGTGCCCA GCGTCGGGGA GTACCTCAAG 
AAGGAGATTG GCCAGCACGT GGCCGGCTGG ACAGAGGATG AGGAGACCAG GAAGCTGAAG 
CTGGCCGTCC TGAACTCCTT CTTCAACCTG GAATGCTGTG TGAGCGGCAC CCACAGCATG 
GACCTGGTGG CCCTGGCACC CTTTGGGGAG TATACCGTGC TGCCGGGGCT GGACTGCACC 
TTTTCTAAGG GCTATCAAGG ACTCACAAAC TGCATGATGG CCGCCCTGCC GGAGGACACT 
GTAGTTTTTG AGAAGCCTGT GAAGACCATC CACTGGAACG GGTCCTTCCA GGAGGCAGCC 
TTTCCCGGGG AGACCTTTCC AGTGTCGGTA GAGTGTGAGG ATGGAGACCG GTTCCCGGCG 
CACCATGTCA TCGTCACCGT GCCCTTAGGT CTGTCCACGT TCTCTGTGGG TTCATTGCCG 
GACTTGAGTC TGAGTTCATG GAGACTCTGT CGGATGAAGA AGTACTTCTG TGTCTCACCC 
AAGTGCTCCG GAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Integrative analysis of copy number and gene expression data suggests novel pathogenetic mechanisms in primary myelofibrosis.
International journal of cancer138(7)1657-69(2016 Apr)
Salati S,Zini R,Nuzzo S,Guglielmelli P,Pennucci V,Prudente Z,Ruberti S,Rontauroli S,Norfo R,Bianchi E,Bogani C,Rotunno G,Fanelli T,Mannarelli C,Rosti V,Salmoiraghi S,Pietra D,Ferrari S,Barosi G,Rambaldi A,Cazzola M,Bicciato S,Tagliafico E,Vannucchi AM,Manfredini R,

An atlas of genetic influences on human blood metabolites.
Nature genetics46(6)543-550(2014 Jun)
Shin SY,Fauman EB,Petersen AK,Krumsiek J,Santos R,Huang J,Arnold M,Erte I,Forgetta V,Yang TP,Walter K,Menni C,Chen L,Vasquez L,Valdes AM,Hyde CL,Wang V,Ziemek D,Roberts P,Xi L,Grundberg E,,Waldenberger M,Richards JB,Mohney RP,Milburn MV,John SL,Trimmer J,Theis FJ,Overington JP,Suhre K,Brosnan MJ,Gieger C,Kastenm?ller G,Spector TD,Soranzo N

Does polyamine oxidase activity influence the oxidative metabolism of children who suffer of diabetes mellitus?
Molecular and cellular biochemistry341(1-2)79-85(2010 Aug)
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A proteome-wide perspective on peroxisome targeting signal 1(PTS1)-Pex5p affinities.
Journal of the American Chemical Society132(11)3973-9(2010 Mar)
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Guide molecule-driven stereospecific degradation of alpha-methylpolyamines by polyamine oxidase.
The Journal of biological chemistry281(8)4589-95(2006 Feb)
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PAOX cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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