Gene Symbol | PHC1 |
Entrez Gene ID | 1911 |
Full Name | polyhomeotic homolog 1 |
Synonyms | EDR1,HPH1,MCPH11,RAE28 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. The gene product, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | ?Microcephaly 11, primary, autosomal recessive, 615414 (3) |