Gene Symbol | EDNRA |
Entrez Gene ID | 1909 |
Full Name | endothelin receptor type A |
Synonyms | ET-A,ETA,ETA-R,ETAR,ETRA,MFDA,hET-AR |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]. |
Disorder MIM: | |
Disorder Html: | {Migraine, resistance to}, 157300 (3); Mandibulofacial dysostosis with alopecia, 616367 (3) |