Gene Symbol | S1PR1 |
Entrez Gene ID | 1901 |
Full Name | sphingosine-1-phosphate receptor 1 |
Synonyms | CD363,CHEDG1,D1S3362,ECGF1,EDG-1,EDG1,S1P1 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]. |
Disorder MIM: |