DIO1 gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
NM_001039716.1	NP_001034805.1	type I iodothyronine deiodinase isoform d
NM_001039716.3	NP_001034805.1	type I iodothyronine deiodinase isoform d
NM_001039715.3	NP_001034804.1	type I iodothyronine deiodinase isoform c
NM_000792.6	NP_000783.2	type I iodothyronine deiodinase isoform a
NM_000792.5	NP_000783.2	type I iodothyronine deiodinase isoform a
NM_001324316.1	NP_001311245.1	type I iodothyronine deiodinase isoform e
NM_001039715.2	NP_001034804.1	type I iodothyronine deiodinase isoform c
NM_213593.5	NP_998758.1	type I iodothyronine deiodinase isoform b
NM_213593.4	NP_998758.1	type I iodothyronine deiodinase isoform b
NM_001039716.2	NP_001034805.1	type I iodothyronine deiodinase isoform d
NM_000792.7	NP_000783.2	type I iodothyronine deiodinase isoform a
NM_001324316.2	NP_001311245.1	type I iodothyronine deiodinase isoform e

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18931	NM_000792.7 Latest version!	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$134.50-$188.30 $269.00
OHu30106	NM_001039716.3 Latest version!	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu13519	NM_213593.5 Latest version!	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu30032	NM_001039715.3 Latest version!	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OHu100740	NM_001324316.2 Latest version!	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu30106	NM_001039716.1	Homo sapiens deiodinase, iodothyronine, type I (DIO1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu18931	NM_000792.5	Homo sapiens deiodinase, iodothyronine, type I (DIO1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$134.50-$188.30 $269.00
OHu30032	NM_001039715.2	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00
OHu13519	NM_213593.4	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu30106	NM_001039716.2	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu18931	NM_000792.6	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$134.50-$188.30 $269.00
OHu100740	NM_001324316.1	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
Hide Old Accession Versions >>

DIO1 ( NM_000792.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_000783.2 Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18931
Clone ID Related Accession (Same CDS sequence)	NM_000792.6 , NM_000792.5 , NM_000792.7
Accession Version	NM_000792.6	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 750bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	type I iodothyronine deiodinase isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290780.1, BC017955.1 and BE046205.1. This sequence is a reference standard in the RefSeqGene project. On Apr 26, 2016 this sequence version replaced NM_000792.5. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK290780.1, ERR279838.5856.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: PMID: 1400883, 12775843 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGGTA ATAGGCCACT GGTGCTGAAT 
TTTGGAAGTT GTACCTGACC TTCATTTATG TTCAAATTTG ACCAGTTCAA GAGGCTTATT 
GAAGACTTTA GTTCCATAGC AGATTTTCTT GTCATTTACA TTGAAGAAGC ACATGCATCA 
GATGGCTGGG CTTTTAAGAA CAACATGGAC ATCAGAAATC ACCAGAACCT TCAGGATCGC 
CTGCAGGCAG CCCATCTACT GCTGGCCAGG AGCCCCCAGT GCCCTGTGGT GGTGGACACC 
ATGCAGAACC AGAGCAGCCA GCTCTACGCA GCACTGCCTG AGAGGCTCTA CATAATCCAG 
GAGGGCAGGA TCCTCTACAA GGGTAAATCT GGCCCTTGGA ACTACAACCC AGAGGAAGTT 
CGTGCTGTTC TGGAAAAGCT CCACAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000783.2
CDS	25..774
Translation	MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDNWIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQGNRPLVLNFGSCT*PSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKNNMDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGPWNYNPEEVRAVLEKLHS

Target ORF information:

RefSeq Version	NM_000792.6
Organism	Homo sapiens(human)
Definition	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000792.6

ORF Insert Sequence:

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGGTA ATAGGCCACT GGTGCTGAAT 
TTTGGAAGTT GTACCTGACC TTCATTTATG TTCAAATTTG ACCAGTTCAA GAGGCTTATT 
GAAGACTTTA GTTCCATAGC AGATTTTCTT GTCATTTACA TTGAAGAAGC ACATGCATCA 
GATGGCTGGG CTTTTAAGAA CAACATGGAC ATCAGAAATC ACCAGAACCT TCAGGATCGC 
CTGCAGGCAG CCCATCTACT GCTGGCCAGG AGCCCCCAGT GCCCTGTGGT GGTGGACACC 
ATGCAGAACC AGAGCAGCCA GCTCTACGCA GCACTGCCTG AGAGGCTCTA CATAATCCAG 
GAGGGCAGGA TCCTCTACAA GGGTAAATCT GGCCCTTGGA ACTACAACCC AGAGGAAGTT 
CGTGCTGTTC TGGAAAAGCT CCACAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIO1 ( NM_000792.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_000783.2 Homo sapiens deiodinase, iodothyronine, type I (DIO1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18931
Clone ID Related Accession (Same CDS sequence)	NM_000792.6 , NM_000792.5 , NM_000792.7
Accession Version	NM_000792.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 750bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-07-09
Organism	Homo sapiens(Human)
Product	type I iodothyronine deiodinase isoform a
Comment

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGGTA ATAGGCCACT GGTGCTGAAT 
TTTGGAAGTT GTACCTGACC TTCATTTATG TTCAAATTTG ACCAGTTCAA GAGGCTTATT 
GAAGACTTTA GTTCCATAGC AGATTTTCTT GTCATTTACA TTGAAGAAGC ACATGCATCA 
GATGGCTGGG CTTTTAAGAA CAACATGGAC ATCAGAAATC ACCAGAACCT TCAGGATCGC 
CTGCAGGCAG CCCATCTACT GCTGGCCAGG AGCCCCCAGT GCCCTGTGGT GGTGGACACC 
ATGCAGAACC AGAGCAGCCA GCTCTACGCA GCACTGCCTG AGAGGCTCTA CATAATCCAG 
GAGGGCAGGA TCCTCTACAA GGGTAAATCT GGCCCTTGGA ACTACAACCC AGAGGAAGTT 
CGTGCTGTTC TGGAAAAGCT CCACAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000783.2
Translation	MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDNWIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQGNRPLVLNFGSCT*PSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKNNMDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGPWNYNPEEVRAVLEKLHS

Target ORF information:

RefSeq Version	NM_000792.5
Organism	Homo sapiens(Human)
Definition	Homo sapiens deiodinase, iodothyronine, type I (DIO1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000792.5

ORF Insert Sequence:

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGGTA ATAGGCCACT GGTGCTGAAT 
TTTGGAAGTT GTACCTGACC TTCATTTATG TTCAAATTTG ACCAGTTCAA GAGGCTTATT 
GAAGACTTTA GTTCCATAGC AGATTTTCTT GTCATTTACA TTGAAGAAGC ACATGCATCA 
GATGGCTGGG CTTTTAAGAA CAACATGGAC ATCAGAAATC ACCAGAACCT TCAGGATCGC 
CTGCAGGCAG CCCATCTACT GCTGGCCAGG AGCCCCCAGT GCCCTGTGGT GGTGGACACC 
ATGCAGAACC AGAGCAGCCA GCTCTACGCA GCACTGCCTG AGAGGCTCTA CATAATCCAG 
GAGGGCAGGA TCCTCTACAA GGGTAAATCT GGCCCTTGGA ACTACAACCC AGAGGAAGTT 
CGTGCTGTTC TGGAAAAGCT CCACAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIO1 ( NM_000792.7 ) cDNA ORF clone, Homo sapiens(human) -> NP_000783.2 Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18931
Clone ID Related Accession (Same CDS sequence)	NM_000792.6 , NM_000792.5 , NM_000792.7
Accession Version	NM_000792.7 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 750bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Homo sapiens(human)
Product	type I iodothyronine deiodinase isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290780.1, BC017955.1 and BE046205.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_000792.6. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189664.99654.1, SRR5189664.83684.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: PMID: 1400883, 12775843 RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGGTA ATAGGCCACT GGTGCTGAAT 
TTTGGAAGTT GTACCTGACC TTCATTTATG TTCAAATTTG ACCAGTTCAA GAGGCTTATT 
GAAGACTTTA GTTCCATAGC AGATTTTCTT GTCATTTACA TTGAAGAAGC ACATGCATCA 
GATGGCTGGG CTTTTAAGAA CAACATGGAC ATCAGAAATC ACCAGAACCT TCAGGATCGC 
CTGCAGGCAG CCCATCTACT GCTGGCCAGG AGCCCCCAGT GCCCTGTGGT GGTGGACACC 
ATGCAGAACC AGAGCAGCCA GCTCTACGCA GCACTGCCTG AGAGGCTCTA CATAATCCAG 
GAGGGCAGGA TCCTCTACAA GGGTAAATCT GGCCCTTGGA ACTACAACCC AGAGGAAGTT 
CGTGCTGTTC TGGAAAAGCT CCACAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000783.2
CDS	25..774
Translation	MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDNWIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQGNRPLVLNFGSCT*PSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKNNMDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGPWNYNPEEVRAVLEKLHS

Target ORF information:

RefSeq Version	NM_000792.7
Organism	Homo sapiens(human)
Definition	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000792.7

ORF Insert Sequence:

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGGTA ATAGGCCACT GGTGCTGAAT 
TTTGGAAGTT GTACCTGACC TTCATTTATG TTCAAATTTG ACCAGTTCAA GAGGCTTATT 
GAAGACTTTA GTTCCATAGC AGATTTTCTT GTCATTTACA TTGAAGAAGC ACATGCATCA 
GATGGCTGGG CTTTTAAGAA CAACATGGAC ATCAGAAATC ACCAGAACCT TCAGGATCGC 
CTGCAGGCAG CCCATCTACT GCTGGCCAGG AGCCCCCAGT GCCCTGTGGT GGTGGACACC 
ATGCAGAACC AGAGCAGCCA GCTCTACGCA GCACTGCCTG AGAGGCTCTA CATAATCCAG 
GAGGGCAGGA TCCTCTACAA GGGTAAATCT GGCCCTTGGA ACTACAACCC AGAGGAAGTT 
CGTGCTGTTC TGGAAAAGCT CCACAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIO1 ( NM_001039716.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034805.1 Homo sapiens deiodinase, iodothyronine, type I (DIO1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu30106
Clone ID Related Accession (Same CDS sequence)	NM_001039716.1 , NM_001039716.3 , NM_001039716.2
Accession Version	NM_001039716.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 486bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-07-09
Organism	Homo sapiens(Human)
Product	type I iodothyronine deiodinase isoform d
Comment

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGGTA ATAGGCCACT GGTGCTGAAT 
TTTGGAAGTT GTACCTGACC TTCATTTATG TTCAAATTTG ACCAGTTCAA GAGGCTTATT 
GAAGACTTTA GTTCCATAGC AGATTTTCTT GTCATTTACA TTGAAGAAGC ACATGCATCA 
GGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034805.1
Translation	MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDNWIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQGNRPLVLNFGSCT*PSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASG

Target ORF information:

RefSeq Version	NM_001039716.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens deiodinase, iodothyronine, type I (DIO1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039716.1

ORF Insert Sequence:

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGGTA ATAGGCCACT GGTGCTGAAT 
TTTGGAAGTT GTACCTGACC TTCATTTATG TTCAAATTTG ACCAGTTCAA GAGGCTTATT 
GAAGACTTTA GTTCCATAGC AGATTTTCTT GTCATTTACA TTGAAGAAGC ACATGCATCA 
GGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIO1 ( NM_001039716.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034805.1 Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu30106
Clone ID Related Accession (Same CDS sequence)	NM_001039716.1 , NM_001039716.3 , NM_001039716.2
Accession Version	NM_001039716.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 486bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-09
Organism	Homo sapiens(human)
Product	type I iodothyronine deiodinase isoform d
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290780.1, BC017955.1 and BE046205.1. On Jun 2, 2019 this sequence version replaced NM_001039716.2. Transcript Variant: This variant (4) lacks an exon in the 3' coding region, which causes a frameshift compared to variant 1. The resulting isoform (d) is shorter, with a distinct C-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC017955.1, BG426442.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: PMID: 1400883, 12775843 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGGTA ATAGGCCACT GGTGCTGAAT 
TTTGGAAGTT GTACCTGACC TTCATTTATG TTCAAATTTG ACCAGTTCAA GAGGCTTATT 
GAAGACTTTA GTTCCATAGC AGATTTTCTT GTCATTTACA TTGAAGAAGC ACATGCATCA 
GGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034805.1
CDS	25..510
Translation	MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDNWIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQGNRPLVLNFGSCT*PSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASG

Target ORF information:

RefSeq Version	NM_001039716.3
Organism	Homo sapiens(human)
Definition	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039716.3

ORF Insert Sequence:

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGGTA ATAGGCCACT GGTGCTGAAT 
TTTGGAAGTT GTACCTGACC TTCATTTATG TTCAAATTTG ACCAGTTCAA GAGGCTTATT 
GAAGACTTTA GTTCCATAGC AGATTTTCTT GTCATTTACA TTGAAGAAGC ACATGCATCA 
GGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIO1 ( NM_001039716.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034805.1 Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu30106
Clone ID Related Accession (Same CDS sequence)	NM_001039716.1 , NM_001039716.3 , NM_001039716.2
Accession Version	NM_001039716.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 486bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	type I iodothyronine deiodinase isoform d
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290780.1, BC017955.1 and BE046205.1. On Apr 26, 2016 this sequence version replaced NM_001039716.1. Transcript Variant: This variant (4) lacks an exon in the 3' coding region, which causes a frameshift compared to variant 1. The resulting isoform (d) is shorter, with a distinct C-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC017955.1, BG426442.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: PMID: 1400883, 12775843 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGGTA ATAGGCCACT GGTGCTGAAT 
TTTGGAAGTT GTACCTGACC TTCATTTATG TTCAAATTTG ACCAGTTCAA GAGGCTTATT 
GAAGACTTTA GTTCCATAGC AGATTTTCTT GTCATTTACA TTGAAGAAGC ACATGCATCA 
GGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034805.1
CDS	25..510
Translation	MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDNWIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQGNRPLVLNFGSCT*PSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASG

Target ORF information:

RefSeq Version	NM_001039716.2
Organism	Homo sapiens(human)
Definition	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039716.2

ORF Insert Sequence:

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGGTA ATAGGCCACT GGTGCTGAAT 
TTTGGAAGTT GTACCTGACC TTCATTTATG TTCAAATTTG ACCAGTTCAA GAGGCTTATT 
GAAGACTTTA GTTCCATAGC AGATTTTCTT GTCATTTACA TTGAAGAAGC ACATGCATCA 
GGGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIO1 ( NM_213593.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_998758.1 Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu13519
Clone ID Related Accession (Same CDS sequence)	NM_213593.5 , NM_213593.4
Accession Version	NM_213593.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-09
Organism	Homo sapiens(human)
Product	type I iodothyronine deiodinase isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290780.1, AY560375.1, BC017955.1 and BE046205.1. On Jun 2, 2019 this sequence version replaced NM_213593.4. Transcript Variant: This variant (2) uses an alternate in-frame donor splice site at the 5' terminal exon compared to variant 1. The resulting isoform (b) is shorter, lacking a 64 aa protein segment in the 5' coding region compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CD014030.1, AY560375.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: PMID: 1400883, 12775843 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTAAT AGGCCACTGG TGCTGAATTT TGGAAGTTGT 
ACCTGACCTT CATTTATGTT CAAATTTGAC CAGTTCAAGA GGCTTATTGA AGACTTTAGT 
TCCATAGCAG ATTTTCTTGT CATTTACATT GAAGAAGCAC ATGCATCAGA TGGCTGGGCT 
TTTAAGAACA ACATGGACAT CAGAAATCAC CAGAACCTTC AGGATCGCCT GCAGGCAGCC 
CATCTACTGC TGGCCAGGAG CCCCCAGTGC CCTGTGGTGG TGGACACCAT GCAGAACCAG 
AGCAGCCAGC TCTACGCAGC ACTGCCTGAG AGGCTCTACA TAATCCAGGA GGGCAGGATC 
CTCTACAAGG GTAAATCTGG CCCTTGGAAC TACAACCCAG AGGAAGTTCG TGCTGTTCTG 
GAAAAGCTCC ACAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_998758.1
CDS	25..582
Translation	MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGNRPLVLNFGSCT*PSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKNNMDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGPWNYNPEEVRAVLEKLHS

Target ORF information:

RefSeq Version	NM_213593.5
Organism	Homo sapiens(human)
Definition	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_213593.5

ORF Insert Sequence:

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTAAT AGGCCACTGG TGCTGAATTT TGGAAGTTGT 
ACCTGACCTT CATTTATGTT CAAATTTGAC CAGTTCAAGA GGCTTATTGA AGACTTTAGT 
TCCATAGCAG ATTTTCTTGT CATTTACATT GAAGAAGCAC ATGCATCAGA TGGCTGGGCT 
TTTAAGAACA ACATGGACAT CAGAAATCAC CAGAACCTTC AGGATCGCCT GCAGGCAGCC 
CATCTACTGC TGGCCAGGAG CCCCCAGTGC CCTGTGGTGG TGGACACCAT GCAGAACCAG 
AGCAGCCAGC TCTACGCAGC ACTGCCTGAG AGGCTCTACA TAATCCAGGA GGGCAGGATC 
CTCTACAAGG GTAAATCTGG CCCTTGGAAC TACAACCCAG AGGAAGTTCG TGCTGTTCTG 
GAAAAGCTCC ACAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIO1 ( NM_213593.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_998758.1 Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu13519
Clone ID Related Accession (Same CDS sequence)	NM_213593.5 , NM_213593.4
Accession Version	NM_213593.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	type I iodothyronine deiodinase isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290780.1, AY560375.1, BC017955.1 and BE046205.1. On Apr 26, 2016 this sequence version replaced NM_213593.3. Transcript Variant: This variant (2) uses an alternate in-frame donor splice site at the 5' terminal exon compared to variant 1. The resulting isoform (b) is shorter, lacking a 64 aa protein segment in the 5' coding region compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CD014030.1, AY560375.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: PMID: 1400883, 12775843 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTAAT AGGCCACTGG TGCTGAATTT TGGAAGTTGT 
ACCTGACCTT CATTTATGTT CAAATTTGAC CAGTTCAAGA GGCTTATTGA AGACTTTAGT 
TCCATAGCAG ATTTTCTTGT CATTTACATT GAAGAAGCAC ATGCATCAGA TGGCTGGGCT 
TTTAAGAACA ACATGGACAT CAGAAATCAC CAGAACCTTC AGGATCGCCT GCAGGCAGCC 
CATCTACTGC TGGCCAGGAG CCCCCAGTGC CCTGTGGTGG TGGACACCAT GCAGAACCAG 
AGCAGCCAGC TCTACGCAGC ACTGCCTGAG AGGCTCTACA TAATCCAGGA GGGCAGGATC 
CTCTACAAGG GTAAATCTGG CCCTTGGAAC TACAACCCAG AGGAAGTTCG TGCTGTTCTG 
GAAAAGCTCC ACAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_998758.1
CDS	25..582
Translation	MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGNRPLVLNFGSCT*PSFMFKFDQFKRLIEDFSSIADFLVIYIEEAHASDGWAFKNNMDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGPWNYNPEEVRAVLEKLHS

Target ORF information:

RefSeq Version	NM_213593.4
Organism	Homo sapiens(human)
Definition	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_213593.4

ORF Insert Sequence:

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTAAT AGGCCACTGG TGCTGAATTT TGGAAGTTGT 
ACCTGACCTT CATTTATGTT CAAATTTGAC CAGTTCAAGA GGCTTATTGA AGACTTTAGT 
TCCATAGCAG ATTTTCTTGT CATTTACATT GAAGAAGCAC ATGCATCAGA TGGCTGGGCT 
TTTAAGAACA ACATGGACAT CAGAAATCAC CAGAACCTTC AGGATCGCCT GCAGGCAGCC 
CATCTACTGC TGGCCAGGAG CCCCCAGTGC CCTGTGGTGG TGGACACCAT GCAGAACCAG 
AGCAGCCAGC TCTACGCAGC ACTGCCTGAG AGGCTCTACA TAATCCAGGA GGGCAGGATC 
CTCTACAAGG GTAAATCTGG CCCTTGGAAC TACAACCCAG AGGAAGTTCG TGCTGTTCTG 
GAAAAGCTCC ACAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIO1 ( NM_001039715.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034804.1 Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu30032
Clone ID Related Accession (Same CDS sequence)	NM_001039715.3 , NM_001039715.2
Accession Version	NM_001039715.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-09
Organism	Homo sapiens(human)
Product	type I iodothyronine deiodinase isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290780.1, AY560377.1, BC017955.1 and BE046205.1. On Jun 2, 2019 this sequence version replaced NM_001039715.2. Transcript Variant: This variant (3) lacks an in-frame exon in the coding region compared to variant 1. The resulting isoform (c) is shorter, lacking an internal selenocysteine-containing protein segment compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7346977.656111.1, BP274525.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGATG GCTGGGCTTT TAAGAACAAC 
ATGGACATCA GAAATCACCA GAACCTTCAG GATCGCCTGC AGGCAGCCCA TCTACTGCTG 
GCCAGGAGCC CCCAGTGCCC TGTGGTGGTG GACACCATGC AGAACCAGAG CAGCCAGCTC 
TACGCAGCAC TGCCTGAGAG GCTCTACATA ATCCAGGAGG GCAGGATCCT CTACAAGGGT 
AAATCTGGCC CTTGGAACTA CAACCCAGAG GAAGTTCGTG CTGTTCTGGA AAAGCTCCAC 
AGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034804.1
CDS	25..630
Translation	MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDNWIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQDGWAFKNNMDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGPWNYNPEEVRAVLEKLHS

Target ORF information:

RefSeq Version	NM_001039715.3
Organism	Homo sapiens(human)
Definition	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039715.3

ORF Insert Sequence:

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGATG GCTGGGCTTT TAAGAACAAC 
ATGGACATCA GAAATCACCA GAACCTTCAG GATCGCCTGC AGGCAGCCCA TCTACTGCTG 
GCCAGGAGCC CCCAGTGCCC TGTGGTGGTG GACACCATGC AGAACCAGAG CAGCCAGCTC 
TACGCAGCAC TGCCTGAGAG GCTCTACATA ATCCAGGAGG GCAGGATCCT CTACAAGGGT 
AAATCTGGCC CTTGGAACTA CAACCCAGAG GAAGTTCGTG CTGTTCTGGA AAAGCTCCAC 
AGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIO1 ( NM_001039715.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034804.1 Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu30032
Clone ID Related Accession (Same CDS sequence)	NM_001039715.3 , NM_001039715.2
Accession Version	NM_001039715.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 606bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-16
Organism	Homo sapiens(human)
Product	type I iodothyronine deiodinase isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290780.1, AY560377.1, BC017955.1 and BE046205.1. On Apr 26, 2016 this sequence version replaced NM_001039715.1. Transcript Variant: This variant (3) lacks an in-frame exon in the coding region compared to variant 1. The resulting isoform (c) is shorter, lacking an internal selenocysteine-containing protein segment compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BP274525.1, CD014029.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGATG GCTGGGCTTT TAAGAACAAC 
ATGGACATCA GAAATCACCA GAACCTTCAG GATCGCCTGC AGGCAGCCCA TCTACTGCTG 
GCCAGGAGCC CCCAGTGCCC TGTGGTGGTG GACACCATGC AGAACCAGAG CAGCCAGCTC 
TACGCAGCAC TGCCTGAGAG GCTCTACATA ATCCAGGAGG GCAGGATCCT CTACAAGGGT 
AAATCTGGCC CTTGGAACTA CAACCCAGAG GAAGTTCGTG CTGTTCTGGA AAAGCTCCAC 
AGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034804.1
CDS	25..630
Translation	MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDNWIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQDGWAFKNNMDIRNHQNLQDRLQAAHLLLARSPQCPVVVDTMQNQSSQLYAALPERLYIIQEGRILYKGKSGPWNYNPEEVRAVLEKLHS

Target ORF information:

RefSeq Version	NM_001039715.2
Organism	Homo sapiens(human)
Definition	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039715.2

ORF Insert Sequence:

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGATG GCTGGGCTTT TAAGAACAAC 
ATGGACATCA GAAATCACCA GAACCTTCAG GATCGCCTGC AGGCAGCCCA TCTACTGCTG 
GCCAGGAGCC CCCAGTGCCC TGTGGTGGTG GACACCATGC AGAACCAGAG CAGCCAGCTC 
TACGCAGCAC TGCCTGAGAG GCTCTACATA ATCCAGGAGG GCAGGATCCT CTACAAGGGT 
AAATCTGGCC CTTGGAACTA CAACCCAGAG GAAGTTCGTG CTGTTCTGGA AAAGCTCCAC 
AGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIO1 ( NM_001324316.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001311245.1 Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu100740
Clone ID Related Accession (Same CDS sequence)	NM_001324316.1 , NM_001324316.2
Accession Version	NM_001324316.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 342bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-21
Organism	Homo sapiens(human)
Product	type I iodothyronine deiodinase isoform e
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290780.1, AY560381.1, BC017955.1 and BE046205.1. Transcript Variant: This variant (5) lacks two internal exons, which causes a frameshift compared to variant 1. The resulting shorter isoform (e) has the same N-terminus but a distinct C-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: JK990798.1, AY560381.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001311245.1
CDS	25..366
Translation	MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDNWIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQG

Target ORF information:

RefSeq Version	NM_001324316.1
Organism	Homo sapiens(human)
Definition	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001324316.1

ORF Insert Sequence:

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIO1 ( NM_001324316.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001311245.1 Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 5, mRNA.

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CloneID	OHu100740
Clone ID Related Accession (Same CDS sequence)	NM_001324316.1 , NM_001324316.2
Accession Version	NM_001324316.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 342bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-09
Organism	Homo sapiens(human)
Product	type I iodothyronine deiodinase isoform e
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK290780.1, AY560381.1, BC017955.1 and BE046205.1. On Jun 2, 2019 this sequence version replaced NM_001324316.1. Transcript Variant: This variant (5) lacks two internal exons, which causes a frameshift compared to variant 1. The resulting shorter isoform (e) has the same N-terminus but a distinct C-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: JK990798.1, AY560381.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001311245.1
CDS	25..366
Translation	MGLPQPGLWLKRLWVLLEVAVHVVVGKVLLILFPDRVKRNILAMGEKTGMTRNPHFSHDNWIPTFFSTQYFWFVLKVRWQRLEDTTELGGLAPNCPVVRLSGQRCNIWEFMQG

Target ORF information:

RefSeq Version	NM_001324316.2
Organism	Homo sapiens(human)
Definition	Homo sapiens iodothyronine deiodinase 1 (DIO1), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001324316.2

ORF Insert Sequence:

ATGGGGCTGC CCCAGCCAGG GCTGTGGCTG AAGAGGCTCT GGGTGCTCTT GGAGGTGGCT 
GTGCATGTGG TCGTGGGTAA AGTGCTTCTG ATATTGTTTC CAGACAGAGT CAAGCGGAAC 
ATCCTGGCCA TGGGCGAGAA GACGGGTATG ACCAGGAACC CCCATTTCAG CCACGACAAC 
TGGATACCAA CCTTTTTCAG CACCCAGTAT TTCTGGTTCG TCTTGAAGGT CCGTTGGCAG 
CGACTAGAGG ACACGACTGA GCTAGGGGGT CTGGCCCCAA ACTGCCCGGT GGTCCGCCTC 
TCAGGACAGA GGTGCAACAT TTGGGAGTTT ATGCAAGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	DIO1
Entrez Gene ID	1733
Full Name	iodothyronine deiodinase 1
Synonyms	5DI,TXDI1
General protein information	Preferred Names iodothyronine deiodinase 1 Names type I iodothyronine deiodinase DIOI deiodinase, iodothyronine type I iodothyronine deiodinase type 1 thyroxine 5'-deiodinase thyroxine deiodinase type I (selenoprotein) type 1 DI type-I 5'-deiodinase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p32.3
Summary	The protein encoded by this gene belongs to the iodothyronine deiodinase family. It catalyzes the activation, as well as the inactivation of thyroid hormone by outer and inner ring deiodination, respectively. The activation reaction involves the conversion of the prohormone thyroxine (3,5,3',5'-tetraiodothyronine, T4), secreted by the thyroid gland, to the bioactive thyroid hormone (3,5,3'-triiodothyronine, T3) by 5'-deiodination. This protein is expressed predominantly in the liver and kidney and provides most of the circulating T3, which is essential for growth, differentiation and basal metabolism in vertebrates. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2016].
Disorder MIM:	147892

Bos taurus (cattle)	DIO1	NP_001116065.1
Rattus norvegicus (Norway rat)	Dio1	NP_067685.5
Gallus gallus (chicken)	DIO1	NP_001091083.1
Danio rerio (zebrafish)	dio1	NP_001007284.2
Xenopus tropicalis (tropical clawed frog)	dio1	NP_001243226.1
Homo sapiens (human)	DIO1	NP_000783.2
Canis lupus familiaris (dog)	DIO1	NP_001007127.1
	DIO1	NP_001116124.1
Mus musculus (house mouse)	Dio1	NP_031886.3
Pan troglodytes (chimpanzee)	DIO1	NP_001116123.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

DIO1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

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