DIAPH2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DIAPH2
Entrez Gene ID	1730
Full Name	diaphanous related formin 2
Synonyms	DIA,DIA2,DRF2,POF,POF2,POF2A
General protein information	Preferred Names diaphanous related formin 2 Names protein diaphanous homolog 2 diaphanous homolog 2 diaphorase-2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq21.33
Summary	The product of this gene belongs to the diaphanous subfamily of the formin homology family of proteins. This gene may play a role in the development and normal function of the ovaries. Defects in this gene have been linked to premature ovarian failure 2. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Disorder MIM:	300108
Disorder Html:	?Premature ovarian failure 2A, 300511 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_007309.3	NP_009293.1	protein diaphanous homolog 2 isoform 12C
NM_006729.4	NP_006720.1	protein diaphanous homolog 2 isoform 156
NM_006729.5	NP_006720.1	protein diaphanous homolog 2 isoform 156

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	DIAPH2	XP_003317594.1
Gallus gallus (chicken)	DIAPH1	NP_989541.1
Danio rerio (zebrafish)	diaph2	XP_683813.6
Homo sapiens (human)	DIAPH2	NP_006720.1
	DIAPH2	XP_001087983.1
Canis lupus familiaris (dog)	DIAPH2	XP_005641605.1

Gene Ontology
Bibliography

Related articles in PubMed

Distinct functions of diaphanous-related formins regulate HIV-1 uncoating and transport.
Delaney MK, Malikov V, Chai Q, Zhao G, Naghavi MH
Proceedings of the National Academy of Sciences of the United States of America114(33)E6932-E6941(2017 Aug)

Essential and nonredundant roles for Diaphanous formins in cortical microtubule capture and directed cell migration.
Daou P, Hasan S, Breitsprecher D, Baudelet E, Camoin L, Audebert S, Goode BL, Badache A
Molecular biology of the cell25(5)658-68(2014 Mar)

Identification of genes promoting skin youthfulness by genome-wide association study.
Chang ALS, Atzmon G, Bergman A, Brugmann S, Atwood SX, Chang HY, Barzilai N
The Journal of investigative dermatology134(3)651-657(2014 Mar)

Inverted formin 2 regulates actin dynamics by antagonizing Rho/diaphanous-related formin signaling.
Sun H, Schlondorff J, Higgs HN, Pollak MR
Journal of the American Society of Nephrology : JASN24(6)917-29(2013 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Dia1, Dia2, and Dia3 are involved in ErbB2-dependent capture of microtubules at the cell leading edge and ErbB2-driven guided migration.
Title: Essential and nonredundant roles for Diaphanous formins in cortical microtubule capture and directed cell migration.

DIAPH2 has been associated with premature ovarian insufficiency, an aging phenotype in humans.
Title: Identification of genes promoting skin youthfulness by genome-wide association study.

In podocytes, INF2 appears to be an important modulator of actin-dependent behaviors that are under the control of Rho/mDia signaling.
Title: Inverted formin 2 regulates actin dynamics by antagonizing Rho/diaphanous-related formin signaling.

Long HIV filopodial formation in infected dendritic cells was dependent on the formin diaphanous 2 (Diaph2)
Title: Mobilization of HIV spread by diaphanous 2 dependent filopodia in infected dendritic cells.

Dia2 and DIP co-tether to nascent blebs and this linkage is required for bleb formation.
Title: Dia-interacting protein (DIP) imposes migratory plasticity in mDia2-dependent tumor cells in three-dimensional matrices.

The following DIAPH2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DIAPH2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15683	NM_007309.3 Latest version!	Homo sapiens diaphanous related formin 2 (DIAPH2), transcript variant 12C, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00
OHu18336	NM_006729.5 Latest version!	Homo sapiens diaphanous related formin 2 (DIAPH2), transcript variant 156, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00
View Old Accession Versions >>
OHu18336	NM_006729.4	Homo sapiens diaphanous related formin 2 (DIAPH2), transcript variant 156, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DIAPH2 ( NM_007309.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_009293.1 Homo sapiens diaphanous related formin 2 (DIAPH2), transcript variant 12C, mRNA.

Price & Availability↑

CloneID	OHu15683
Clone ID Related Accession (Same CDS sequence)	NM_007309.3
Accession Version	NM_007309.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3291bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Homo sapiens(human)
Product	protein diaphanous homolog 2 isoform 12C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX363708.2, Y15909.1 and AW276516.1. On Jun 2, 2008 this sequence version replaced NM_007309.2. Transcript Variant: This variant (12C) differs in the 3' UTR and the 3' coding region, compared to variant 156. The resulting isoform (isoform 12C) contains a distinct C-terminus, compared to isoform 156. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y15908.1, AK291272.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03568912 [ECO:0000348] ##Evidence-Data-END##

ATGGAGCAGC CCGGGGCGGC GGCGTCGGGA GCGGGAGGCG GCAGCGAGGA ACCCGGTGGG 
GGCCGGAGCA ACAAGCGGAG CGCGGGGAAC CGGGCCGCCA ATGAAGAGGA AACGAAAAAC 
AAACCCAAAT TGAACATTCA AATAAAAACT TTGGCAGATG ATGTGCGTGA CCGAATTACA 
AGTTTTAGAA AATCTACTGT CAAAAAAGAA AAACCTCTTA TTCAACATCC TATTGATTCT 
CAAGTCGCGA TGAGTGAGTT TCCTGCAGCT CAGCCATTAT ATGATGAACG ATCTTTGAAT 
TTGTCAGAAA AGGAAGTATT GGATCTCTTT GAAAAAATGA TGGAGGACAT GAACCTTAAC 
GAAGAGAAAA AAGCTCCTTT ACGAAACAAA GACTTTACCA CCAAACGTGA GATGGTTGTC 
CAGTATATTT CTGCCACTGC CAAATCTGGT GGGCTGAAAA ACAGCAAACA TGAATGCACC 
CTGTCTTCAC AAGAATATGT TCATGAATTA CGATCGGGTA TATCAGATGA GAAACTTCTT 
AATTGCCTAG AATCCCTCAG GGTTTCTTTA ACCAGCAATC CGGTCAGCTG GGTTAACAAC 
TTTGGCCATG AAGGTCTTGG ACTCTTATTG GATGAGCTGG AAAAGCTTCT GGACAAAAAA 
CAGCAAGAAA ATATTGACAA GAAGAATCAG TATAAACTTA TTCAATGCCT CAAAGCATTT 
ATGAATAATA AGTTTGGATT ACAAAGGATT CTAGGAGATG AAAGAAGTCT TTTACTATTG 
GCAAGAGCAA TTGACCCCAA ACAACCCAAC ATGATGACTG AAATAGTAAA AATACTTTCT 
GCTATTTGCA TTGTTGGAGA AGAGAACATT CTAGATAAAC TTTTAGGGGC TATAACAACA 
GCAGCAGAAA GAAATAACAG GGAACGATTT TCACCAATTG TGGAAGGTTT AGAAAATCAG 
GAAGCCTTGC AATTACAGGT GGCCTGCATG CAGTTTATAA ATGCCCTTGT CACTTCTCCT 
TATGAGCTTG ATTTTCGAAT ACATTTAAGG AATGAATTCC TCCGTTCAGG ACTAAAAACA 
ATGTTACCAG ATCTAAAAGA AAAAGAGAAT GATGAGCTTG ATATTCAGTT GAAAGTATTT 
GATGAAAACA AAGAAGATGA CCTAACTGAA TTATCACACC GTCTCAATGA CATTCGAGCA 
GAAATGGATG ATATGAATGA AGTCTACCAT CTTCTATATA ATATGCTGAA GGACACTGCT 
GCTGAAAATT ACTTCTTATC TATTCTACAA CATTTTTTGC TTATCAGAAA TGATTATTAT 
ATCAGGCCAC AATATTATAA AATAATTGAG GAATGTGTTT CACAGATAGT GCTACACTGC 
AGTGGTATGG ATCCAGACTT CAAATACAGG CAAAGATTAG ACATCGATTT AACTCATCTG 
ATAGATTCTT GTGTGAACAA GGCGAAAGTT GAAGAAAGTG AACAAAAAGC TGCAGAGTTT 
TCAAAGAAGT TCGATGAAGA ATTCACAGCT CGACAGGAAG CTCAAGCAGA GCTTCAAAAA 
AGAGATGAGA AAATCAAAGA ACTTGAAGCA GAAATCCAGC AACTTCGAAC CCAGGCACAA 
GTACTCTCAA GTTCATCAGG AATTCCAGGT CCTCCTGCAG CACCTCCATT GCCAGGTGTA 
GGGCCGCCTC CACCACCACC CGCGCCACCT CTACCCGGAG GAGCTCCTCT TCCTCCTCCA 
CCACCTCCTT TACCTGGAAT GATGGGGATA CCACCACCAC CCCCACCACC ACTTTTATTT 
GGGGGACCTC CTCCACCACC ACCCCTTGGA GGAGTTCCTC CTCCCCCAGG AATATCACTT 
AATCTACCTT ATGGAATGAA GCAGAAAAAA ATGTATAAAC CTGAAGTGTC CATGAAGAGA 
ATCAATTGGT CAAAGATTGA ACCCACAGAA TTATCTGAGA ACTGTTTCTG GTTAAGAGTC 
AAAGAAGACA AGTTTGAGAA TCCAGATCTC TTTGCCAAAT TGGCATTGAA TTTTGCTACT 
CAGATAAAAG TTCAAAAGAA CGCAGAAGCA TTAGAAGAAA AGAAGACTGG GCCTACAAAG 
AAGAAAGTGA AAGAACTGAG AATTTTGGAT CCCAAAACAG CTCAGAATCT GTCCATCTTT 
CTGGGATCAT ATCGCATGCC ATATGAAGAC ATAAGAAACG TTATTCTGGA GGTTAATGAA 
GACATGCTGA GTGAGGCTTT AATTCAGAAC CTTGTGAAAC ATCTTCCTGA GCAGAAGATA 
CTCAACGAAT TAGCAGAGCT TAAGAATGAA TATGATGACC TCTGTGAGCC TGAACAATTT 
GGAGTTGTGA TGAGCTCTGT GAAAATGTTA CAGCCTCGTC TCAGTAGTAT CCTGTTCAAG 
CTCACATTTG AAGAACACAT AAACAACATC AAACCAAGCA TCATAGCAGT AACTCTTGCC 
TGTGAAGAAC TGAAGAAAAG TGAAAGCTTT AACAGACTTT TAGAGTTAGT TCTTCTTGTT 
GGAAACTACA TGAACTCAGG CTCAAGAAAT GCCCAGTCTT TGGGATTTAA GATCAACTTC 
CTTTGTAAGA TCAGAGATAC TAAATCAGCG GATCAAAAAA CAACCCTTTT GCATTTTATT 
GCCGACATTT GTGAGGAAAA ATATCGAGAT ATCCTAAAAT TTCCTGAAGA ACTGGAACAC 
GTAGAAAGTG CAAGCAAAGT TTCAGCTCAA ATTCTCAAGA GCAACCTTGC ATCAATGGAA 
CAACAAATTG TTCATCTGGA ACGTGACATC AAGAAATTCC CCCAAGCAGA AAATCAACAC 
GATAAGTTTG TGGAAAAGAT GACCAGCTTT ACAAAGACTG CCCGAGAACA GTATGAAAAA 
CTCTCCACCA TGCACAACAA CATGATGAAG CTCTATGAGA ATCTTGGAGA ATACTTCATT 
TTTGACTCAA AGACAGTGAG CATAGAAGAG TTCTTTGGTG ATCTCAACAA CTTCCGAACT 
TTGTTTTTGG AAGCAGTGAG AGAAAACAAT AAGAGAAGAG AAATGGAAGA GAAGACCAGG 
AGGGCAAAAC TTGCAAAAGA GAAAGCTGAA CAAGAAAAGT TAGAACGCCA GAAGAAAAAG 
AAACAACTCA TTGATATAAA CAAAGAGGGT GATGAGACTG GTGTGATGGA TAATCTTCTA 
GAAGCCCTAC AATCAGGTGC AGCATTCAGA GACCGTCGAA AGCGGATTCC AAGGAATCCA 
GTGGTAAATC ATCCCTGTGC AACAAGGGCT AATCCAAGAT CAGCTACATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009293.1
CDS	397..3687
Translation	MEQPGAAASGAGGGSEEPGGGRSNKRSAGNRAANEEETKNKPKLNIQIKTLADDVRDRITSFRKSTVKKEKPLIQHPIDSQVAMSEFPAAQPLYDERSLNLSEKEVLDLFEKMMEDMNLNEEKKAPLRNKDFTTKREMVVQYISATAKSGGLKNSKHECTLSSQEYVHELRSGISDEKLLNCLESLRVSLTSNPVSWVNNFGHEGLGLLLDELEKLLDKKQQENIDKKNQYKLIQCLKAFMNNKFGLQRILGDERSLLLLARAIDPKQPNMMTEIVKILSAICIVGEENILDKLLGAITTAAERNNRERFSPIVEGLENQEALQLQVACMQFINALVTSPYELDFRIHLRNEFLRSGLKTMLPDLKEKENDELDIQLKVFDENKEDDLTELSHRLNDIRAEMDDMNEVYHLLYNMLKDTAAENYFLSILQHFLLIRNDYYIRPQYYKIIEECVSQIVLHCSGMDPDFKYRQRLDIDLTHLIDSCVNKAKVEESEQKAAEFSKKFDEEFTARQEAQAELQKRDEKIKELEAEIQQLRTQAQVLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGVPPPPGISLNLPYGMKQKKMYKPEVSMKRINWSKIEPTELSENCFWLRVKEDKFENPDLFAKLALNFATQIKVQKNAEALEEKKTGPTKKKVKELRILDPKTAQNLSIFLGSYRMPYEDIRNVILEVNEDMLSEALIQNLVKHLPEQKILNELAELKNEYDDLCEPEQFGVVMSSVKMLQPRLSSILFKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGSRNAQSLGFKINFLCKIRDTKSADQKTTLLHFIADICEEKYRDILKFPEELEHVESASKVSAQILKSNLASMEQQIVHLERDIKKFPQAENQHDKFVEKMTSFTKTAREQYEKLSTMHNNMMKLYENLGEYFIFDSKTVSIEEFFGDLNNFRTLFLEAVRENNKRREMEEKTRRAKLAKEKAEQEKLERQKKKKQLIDINKEGDETGVMDNLLEALQSGAAFRDRRKRIPRNPVVNHPCATRANPRSAT

Target ORF information:

RefSeq Version	NM_007309.3
Organism	Homo sapiens(human)
Definition	Homo sapiens diaphanous related formin 2 (DIAPH2), transcript variant 12C, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007309.3

ORF Insert Sequence:

ATGGAGCAGC CCGGGGCGGC GGCGTCGGGA GCGGGAGGCG GCAGCGAGGA ACCCGGTGGG 
GGCCGGAGCA ACAAGCGGAG CGCGGGGAAC CGGGCCGCCA ATGAAGAGGA AACGAAAAAC 
AAACCCAAAT TGAACATTCA AATAAAAACT TTGGCAGATG ATGTGCGTGA CCGAATTACA 
AGTTTTAGAA AATCTACTGT CAAAAAAGAA AAACCTCTTA TTCAACATCC TATTGATTCT 
CAAGTCGCGA TGAGTGAGTT TCCTGCAGCT CAGCCATTAT ATGATGAACG ATCTTTGAAT 
TTGTCAGAAA AGGAAGTATT GGATCTCTTT GAAAAAATGA TGGAGGACAT GAACCTTAAC 
GAAGAGAAAA AAGCTCCTTT ACGAAACAAA GACTTTACCA CCAAACGTGA GATGGTTGTC 
CAGTATATTT CTGCCACTGC CAAATCTGGT GGGCTGAAAA ACAGCAAACA TGAATGCACC 
CTGTCTTCAC AAGAATATGT TCATGAATTA CGATCGGGTA TATCAGATGA GAAACTTCTT 
AATTGCCTAG AATCCCTCAG GGTTTCTTTA ACCAGCAATC CGGTCAGCTG GGTTAACAAC 
TTTGGCCATG AAGGTCTTGG ACTCTTATTG GATGAGCTGG AAAAGCTTCT GGACAAAAAA 
CAGCAAGAAA ATATTGACAA GAAGAATCAG TATAAACTTA TTCAATGCCT CAAAGCATTT 
ATGAATAATA AGTTTGGATT ACAAAGGATT CTAGGAGATG AAAGAAGTCT TTTACTATTG 
GCAAGAGCAA TTGACCCCAA ACAACCCAAC ATGATGACTG AAATAGTAAA AATACTTTCT 
GCTATTTGCA TTGTTGGAGA AGAGAACATT CTAGATAAAC TTTTAGGGGC TATAACAACA 
GCAGCAGAAA GAAATAACAG GGAACGATTT TCACCAATTG TGGAAGGTTT AGAAAATCAG 
GAAGCCTTGC AATTACAGGT GGCCTGCATG CAGTTTATAA ATGCCCTTGT CACTTCTCCT 
TATGAGCTTG ATTTTCGAAT ACATTTAAGG AATGAATTCC TCCGTTCAGG ACTAAAAACA 
ATGTTACCAG ATCTAAAAGA AAAAGAGAAT GATGAGCTTG ATATTCAGTT GAAAGTATTT 
GATGAAAACA AAGAAGATGA CCTAACTGAA TTATCACACC GTCTCAATGA CATTCGAGCA 
GAAATGGATG ATATGAATGA AGTCTACCAT CTTCTATATA ATATGCTGAA GGACACTGCT 
GCTGAAAATT ACTTCTTATC TATTCTACAA CATTTTTTGC TTATCAGAAA TGATTATTAT 
ATCAGGCCAC AATATTATAA AATAATTGAG GAATGTGTTT CACAGATAGT GCTACACTGC 
AGTGGTATGG ATCCAGACTT CAAATACAGG CAAAGATTAG ACATCGATTT AACTCATCTG 
ATAGATTCTT GTGTGAACAA GGCGAAAGTT GAAGAAAGTG AACAAAAAGC TGCAGAGTTT 
TCAAAGAAGT TCGATGAAGA ATTCACAGCT CGACAGGAAG CTCAAGCAGA GCTTCAAAAA 
AGAGATGAGA AAATCAAAGA ACTTGAAGCA GAAATCCAGC AACTTCGAAC CCAGGCACAA 
GTACTCTCAA GTTCATCAGG AATTCCAGGT CCTCCTGCAG CACCTCCATT GCCAGGTGTA 
GGGCCGCCTC CACCACCACC CGCGCCACCT CTACCCGGAG GAGCTCCTCT TCCTCCTCCA 
CCACCTCCTT TACCTGGAAT GATGGGGATA CCACCACCAC CCCCACCACC ACTTTTATTT 
GGGGGACCTC CTCCACCACC ACCCCTTGGA GGAGTTCCTC CTCCCCCAGG AATATCACTT 
AATCTACCTT ATGGAATGAA GCAGAAAAAA ATGTATAAAC CTGAAGTGTC CATGAAGAGA 
ATCAATTGGT CAAAGATTGA ACCCACAGAA TTATCTGAGA ACTGTTTCTG GTTAAGAGTC 
AAAGAAGACA AGTTTGAGAA TCCAGATCTC TTTGCCAAAT TGGCATTGAA TTTTGCTACT 
CAGATAAAAG TTCAAAAGAA CGCAGAAGCA TTAGAAGAAA AGAAGACTGG GCCTACAAAG 
AAGAAAGTGA AAGAACTGAG AATTTTGGAT CCCAAAACAG CTCAGAATCT GTCCATCTTT 
CTGGGATCAT ATCGCATGCC ATATGAAGAC ATAAGAAACG TTATTCTGGA GGTTAATGAA 
GACATGCTGA GTGAGGCTTT AATTCAGAAC CTTGTGAAAC ATCTTCCTGA GCAGAAGATA 
CTCAACGAAT TAGCAGAGCT TAAGAATGAA TATGATGACC TCTGTGAGCC TGAACAATTT 
GGAGTTGTGA TGAGCTCTGT GAAAATGTTA CAGCCTCGTC TCAGTAGTAT CCTGTTCAAG 
CTCACATTTG AAGAACACAT AAACAACATC AAACCAAGCA TCATAGCAGT AACTCTTGCC 
TGTGAAGAAC TGAAGAAAAG TGAAAGCTTT AACAGACTTT TAGAGTTAGT TCTTCTTGTT 
GGAAACTACA TGAACTCAGG CTCAAGAAAT GCCCAGTCTT TGGGATTTAA GATCAACTTC 
CTTTGTAAGA TCAGAGATAC TAAATCAGCG GATCAAAAAA CAACCCTTTT GCATTTTATT 
GCCGACATTT GTGAGGAAAA ATATCGAGAT ATCCTAAAAT TTCCTGAAGA ACTGGAACAC 
GTAGAAAGTG CAAGCAAAGT TTCAGCTCAA ATTCTCAAGA GCAACCTTGC ATCAATGGAA 
CAACAAATTG TTCATCTGGA ACGTGACATC AAGAAATTCC CCCAAGCAGA AAATCAACAC 
GATAAGTTTG TGGAAAAGAT GACCAGCTTT ACAAAGACTG CCCGAGAACA GTATGAAAAA 
CTCTCCACCA TGCACAACAA CATGATGAAG CTCTATGAGA ATCTTGGAGA ATACTTCATT 
TTTGACTCAA AGACAGTGAG CATAGAAGAG TTCTTTGGTG ATCTCAACAA CTTCCGAACT 
TTGTTTTTGG AAGCAGTGAG AGAAAACAAT AAGAGAAGAG AAATGGAAGA GAAGACCAGG 
AGGGCAAAAC TTGCAAAAGA GAAAGCTGAA CAAGAAAAGT TAGAACGCCA GAAGAAAAAG 
AAACAACTCA TTGATATAAA CAAAGAGGGT GATGAGACTG GTGTGATGGA TAATCTTCTA 
GAAGCCCTAC AATCAGGTGC AGCATTCAGA GACCGTCGAA AGCGGATTCC AAGGAATCCA 
GTGGTAAATC ATCCCTGTGC AACAAGGGCT AATCCAAGAT CAGCTACATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIAPH2 ( NM_006729.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006720.1 Homo sapiens diaphanous related formin 2 (DIAPH2), transcript variant 156, mRNA.

Price & Availability↑

CloneID	OHu18336
Clone ID Related Accession (Same CDS sequence)	NM_006729.4 , NM_006729.5
Accession Version	NM_006729.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3306bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	protein diaphanous homolog 2 isoform 156
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX363708.2, Y15909.1, U69179.1 and DB062196.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2008 this sequence version replaced NM_006729.3. Transcript Variant: This variant (156) represents the longer transcript, and encodes the longer isoform (isoform 156). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y15909.1, SRR1803612.128120.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCAGC CCGGGGCGGC GGCGTCGGGA GCGGGAGGCG GCAGCGAGGA ACCCGGTGGG 
GGCCGGAGCA ACAAGCGGAG CGCGGGGAAC CGGGCCGCCA ATGAAGAGGA AACGAAAAAC 
AAACCCAAAT TGAACATTCA AATAAAAACT TTGGCAGATG ATGTGCGTGA CCGAATTACA 
AGTTTTAGAA AATCTACTGT CAAAAAAGAA AAACCTCTTA TTCAACATCC TATTGATTCT 
CAAGTCGCGA TGAGTGAGTT TCCTGCAGCT CAGCCATTAT ATGATGAACG ATCTTTGAAT 
TTGTCAGAAA AGGAAGTATT GGATCTCTTT GAAAAAATGA TGGAGGACAT GAACCTTAAC 
GAAGAGAAAA AAGCTCCTTT ACGAAACAAA GACTTTACCA CCAAACGTGA GATGGTTGTC 
CAGTATATTT CTGCCACTGC CAAATCTGGT GGGCTGAAAA ACAGCAAACA TGAATGCACC 
CTGTCTTCAC AAGAATATGT TCATGAATTA CGATCGGGTA TATCAGATGA GAAACTTCTT 
AATTGCCTAG AATCCCTCAG GGTTTCTTTA ACCAGCAATC CGGTCAGCTG GGTTAACAAC 
TTTGGCCATG AAGGTCTTGG ACTCTTATTG GATGAGCTGG AAAAGCTTCT GGACAAAAAA 
CAGCAAGAAA ATATTGACAA GAAGAATCAG TATAAACTTA TTCAATGCCT CAAAGCATTT 
ATGAATAATA AGTTTGGATT ACAAAGGATT CTAGGAGATG AAAGAAGTCT TTTACTATTG 
GCAAGAGCAA TTGACCCCAA ACAACCCAAC ATGATGACTG AAATAGTAAA AATACTTTCT 
GCTATTTGCA TTGTTGGAGA AGAGAACATT CTAGATAAAC TTTTAGGGGC TATAACAACA 
GCAGCAGAAA GAAATAACAG GGAACGATTT TCACCAATTG TGGAAGGTTT AGAAAATCAG 
GAAGCCTTGC AATTACAGGT GGCCTGCATG CAGTTTATAA ATGCCCTTGT CACTTCTCCT 
TATGAGCTTG ATTTTCGAAT ACATTTAAGG AATGAATTCC TCCGTTCAGG ACTAAAAACA 
ATGTTACCAG ATCTAAAAGA AAAAGAGAAT GATGAGCTTG ATATTCAGTT GAAAGTATTT 
GATGAAAACA AAGAAGATGA CCTAACTGAA TTATCACACC GTCTCAATGA CATTCGAGCA 
GAAATGGATG ATATGAATGA AGTCTACCAT CTTCTATATA ATATGCTGAA GGACACTGCT 
GCTGAAAATT ACTTCTTATC TATTCTACAA CATTTTTTGC TTATCAGAAA TGATTATTAT 
ATCAGGCCAC AATATTATAA AATAATTGAG GAATGTGTTT CACAGATAGT GCTACACTGC 
AGTGGTATGG ATCCAGACTT CAAATACAGG CAAAGATTAG ACATCGATTT AACTCATCTG 
ATAGATTCTT GTGTGAACAA GGCGAAAGTT GAAGAAAGTG AACAAAAAGC TGCAGAGTTT 
TCAAAGAAGT TCGATGAAGA ATTCACAGCT CGACAGGAAG CTCAAGCAGA GCTTCAAAAA 
AGAGATGAGA AAATCAAAGA ACTTGAAGCA GAAATCCAGC AACTTCGAAC CCAGGCACAA 
GTACTCTCAA GTTCATCAGG AATTCCAGGT CCTCCTGCAG CACCTCCATT GCCAGGTGTA 
GGGCCGCCTC CACCACCACC CGCGCCACCT CTACCCGGAG GAGCTCCTCT TCCTCCTCCA 
CCACCTCCTT TACCTGGAAT GATGGGGATA CCACCACCAC CCCCACCACC ACTTTTATTT 
GGGGGACCTC CTCCACCACC ACCCCTTGGA GGAGTTCCTC CTCCCCCAGG AATATCACTT 
AATCTACCTT ATGGAATGAA GCAGAAAAAA ATGTATAAAC CTGAAGTGTC CATGAAGAGA 
ATCAATTGGT CAAAGATTGA ACCCACAGAA TTATCTGAGA ACTGTTTCTG GTTAAGAGTC 
AAAGAAGACA AGTTTGAGAA TCCAGATCTC TTTGCCAAAT TGGCATTGAA TTTTGCTACT 
CAGATAAAAG TTCAAAAGAA CGCAGAAGCA TTAGAAGAAA AGAAGACTGG GCCTACAAAG 
AAGAAAGTGA AAGAACTGAG AATTTTGGAT CCCAAAACAG CTCAGAATCT GTCCATCTTT 
CTGGGATCAT ATCGCATGCC ATATGAAGAC ATAAGAAACG TTATTCTGGA GGTTAATGAA 
GACATGCTGA GTGAGGCTTT AATTCAGAAC CTTGTGAAAC ATCTTCCTGA GCAGAAGATA 
CTCAACGAAT TAGCAGAGCT TAAGAATGAA TATGATGACC TCTGTGAGCC TGAACAATTT 
GGAGTTGTGA TGAGCTCTGT GAAAATGTTA CAGCCTCGTC TCAGTAGTAT CCTGTTCAAG 
CTCACATTTG AAGAACACAT AAACAACATC AAACCAAGCA TCATAGCAGT AACTCTTGCC 
TGTGAAGAAC TGAAGAAAAG TGAAAGCTTT AACAGACTTT TAGAGTTAGT TCTTCTTGTT 
GGAAACTACA TGAACTCAGG CTCAAGAAAT GCCCAGTCTT TGGGATTTAA GATCAACTTC 
CTTTGTAAGA TCAGAGATAC TAAATCAGCG GATCAAAAAA CAACCCTTTT GCATTTTATT 
GCCGACATTT GTGAGGAAAA ATATCGAGAT ATCCTAAAAT TTCCTGAAGA ACTGGAACAC 
GTAGAAAGTG CAAGCAAAGT TTCAGCTCAA ATTCTCAAGA GCAACCTTGC ATCAATGGAA 
CAACAAATTG TTCATCTGGA ACGTGACATC AAGAAATTCC CCCAAGCAGA AAATCAACAC 
GATAAGTTTG TGGAAAAGAT GACCAGCTTT ACAAAGACTG CCCGAGAACA GTATGAAAAA 
CTCTCCACCA TGCACAACAA CATGATGAAG CTCTATGAGA ATCTTGGAGA ATACTTCATT 
TTTGACTCAA AGACAGTGAG CATAGAAGAG TTCTTTGGTG ATCTCAACAA CTTCCGAACT 
TTGTTTTTGG AAGCAGTGAG AGAAAACAAT AAGAGAAGAG AAATGGAAGA GAAGACCAGG 
AGGGCAAAAC TTGCAAAAGA GAAAGCTGAA CAAGAAAAGT TAGAACGCCA GAAGAAAAAG 
AAACAACTCA TTGATATAAA CAAAGAGGGT GATGAGACTG GTGTGATGGA TAATCTTCTA 
GAAGCCCTAC AATCAGGTGC AGCATTCAGA GACCGTCGAA AGCGGATTCC AAGGAATCCA 
GATAACAGAC GAGTACCTTT GGAAAGGTCA CGCTCTCGCC ACAATGGAGC TATCTCATCT 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006720.1
CDS	397..3702
Translation	MEQPGAAASGAGGGSEEPGGGRSNKRSAGNRAANEEETKNKPKLNIQIKTLADDVRDRITSFRKSTVKKEKPLIQHPIDSQVAMSEFPAAQPLYDERSLNLSEKEVLDLFEKMMEDMNLNEEKKAPLRNKDFTTKREMVVQYISATAKSGGLKNSKHECTLSSQEYVHELRSGISDEKLLNCLESLRVSLTSNPVSWVNNFGHEGLGLLLDELEKLLDKKQQENIDKKNQYKLIQCLKAFMNNKFGLQRILGDERSLLLLARAIDPKQPNMMTEIVKILSAICIVGEENILDKLLGAITTAAERNNRERFSPIVEGLENQEALQLQVACMQFINALVTSPYELDFRIHLRNEFLRSGLKTMLPDLKEKENDELDIQLKVFDENKEDDLTELSHRLNDIRAEMDDMNEVYHLLYNMLKDTAAENYFLSILQHFLLIRNDYYIRPQYYKIIEECVSQIVLHCSGMDPDFKYRQRLDIDLTHLIDSCVNKAKVEESEQKAAEFSKKFDEEFTARQEAQAELQKRDEKIKELEAEIQQLRTQAQVLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGVPPPPGISLNLPYGMKQKKMYKPEVSMKRINWSKIEPTELSENCFWLRVKEDKFENPDLFAKLALNFATQIKVQKNAEALEEKKTGPTKKKVKELRILDPKTAQNLSIFLGSYRMPYEDIRNVILEVNEDMLSEALIQNLVKHLPEQKILNELAELKNEYDDLCEPEQFGVVMSSVKMLQPRLSSILFKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGSRNAQSLGFKINFLCKIRDTKSADQKTTLLHFIADICEEKYRDILKFPEELEHVESASKVSAQILKSNLASMEQQIVHLERDIKKFPQAENQHDKFVEKMTSFTKTAREQYEKLSTMHNNMMKLYENLGEYFIFDSKTVSIEEFFGDLNNFRTLFLEAVRENNKRREMEEKTRRAKLAKEKAEQEKLERQKKKKQLIDINKEGDETGVMDNLLEALQSGAAFRDRRKRIPRNPDNRRVPLERSRSRHNGAISSK

Target ORF information:

RefSeq Version	NM_006729.4
Organism	Homo sapiens(human)
Definition	Homo sapiens diaphanous related formin 2 (DIAPH2), transcript variant 156, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006729.4

ORF Insert Sequence:

ATGGAGCAGC CCGGGGCGGC GGCGTCGGGA GCGGGAGGCG GCAGCGAGGA ACCCGGTGGG 
GGCCGGAGCA ACAAGCGGAG CGCGGGGAAC CGGGCCGCCA ATGAAGAGGA AACGAAAAAC 
AAACCCAAAT TGAACATTCA AATAAAAACT TTGGCAGATG ATGTGCGTGA CCGAATTACA 
AGTTTTAGAA AATCTACTGT CAAAAAAGAA AAACCTCTTA TTCAACATCC TATTGATTCT 
CAAGTCGCGA TGAGTGAGTT TCCTGCAGCT CAGCCATTAT ATGATGAACG ATCTTTGAAT 
TTGTCAGAAA AGGAAGTATT GGATCTCTTT GAAAAAATGA TGGAGGACAT GAACCTTAAC 
GAAGAGAAAA AAGCTCCTTT ACGAAACAAA GACTTTACCA CCAAACGTGA GATGGTTGTC 
CAGTATATTT CTGCCACTGC CAAATCTGGT GGGCTGAAAA ACAGCAAACA TGAATGCACC 
CTGTCTTCAC AAGAATATGT TCATGAATTA CGATCGGGTA TATCAGATGA GAAACTTCTT 
AATTGCCTAG AATCCCTCAG GGTTTCTTTA ACCAGCAATC CGGTCAGCTG GGTTAACAAC 
TTTGGCCATG AAGGTCTTGG ACTCTTATTG GATGAGCTGG AAAAGCTTCT GGACAAAAAA 
CAGCAAGAAA ATATTGACAA GAAGAATCAG TATAAACTTA TTCAATGCCT CAAAGCATTT 
ATGAATAATA AGTTTGGATT ACAAAGGATT CTAGGAGATG AAAGAAGTCT TTTACTATTG 
GCAAGAGCAA TTGACCCCAA ACAACCCAAC ATGATGACTG AAATAGTAAA AATACTTTCT 
GCTATTTGCA TTGTTGGAGA AGAGAACATT CTAGATAAAC TTTTAGGGGC TATAACAACA 
GCAGCAGAAA GAAATAACAG GGAACGATTT TCACCAATTG TGGAAGGTTT AGAAAATCAG 
GAAGCCTTGC AATTACAGGT GGCCTGCATG CAGTTTATAA ATGCCCTTGT CACTTCTCCT 
TATGAGCTTG ATTTTCGAAT ACATTTAAGG AATGAATTCC TCCGTTCAGG ACTAAAAACA 
ATGTTACCAG ATCTAAAAGA AAAAGAGAAT GATGAGCTTG ATATTCAGTT GAAAGTATTT 
GATGAAAACA AAGAAGATGA CCTAACTGAA TTATCACACC GTCTCAATGA CATTCGAGCA 
GAAATGGATG ATATGAATGA AGTCTACCAT CTTCTATATA ATATGCTGAA GGACACTGCT 
GCTGAAAATT ACTTCTTATC TATTCTACAA CATTTTTTGC TTATCAGAAA TGATTATTAT 
ATCAGGCCAC AATATTATAA AATAATTGAG GAATGTGTTT CACAGATAGT GCTACACTGC 
AGTGGTATGG ATCCAGACTT CAAATACAGG CAAAGATTAG ACATCGATTT AACTCATCTG 
ATAGATTCTT GTGTGAACAA GGCGAAAGTT GAAGAAAGTG AACAAAAAGC TGCAGAGTTT 
TCAAAGAAGT TCGATGAAGA ATTCACAGCT CGACAGGAAG CTCAAGCAGA GCTTCAAAAA 
AGAGATGAGA AAATCAAAGA ACTTGAAGCA GAAATCCAGC AACTTCGAAC CCAGGCACAA 
GTACTCTCAA GTTCATCAGG AATTCCAGGT CCTCCTGCAG CACCTCCATT GCCAGGTGTA 
GGGCCGCCTC CACCACCACC CGCGCCACCT CTACCCGGAG GAGCTCCTCT TCCTCCTCCA 
CCACCTCCTT TACCTGGAAT GATGGGGATA CCACCACCAC CCCCACCACC ACTTTTATTT 
GGGGGACCTC CTCCACCACC ACCCCTTGGA GGAGTTCCTC CTCCCCCAGG AATATCACTT 
AATCTACCTT ATGGAATGAA GCAGAAAAAA ATGTATAAAC CTGAAGTGTC CATGAAGAGA 
ATCAATTGGT CAAAGATTGA ACCCACAGAA TTATCTGAGA ACTGTTTCTG GTTAAGAGTC 
AAAGAAGACA AGTTTGAGAA TCCAGATCTC TTTGCCAAAT TGGCATTGAA TTTTGCTACT 
CAGATAAAAG TTCAAAAGAA CGCAGAAGCA TTAGAAGAAA AGAAGACTGG GCCTACAAAG 
AAGAAAGTGA AAGAACTGAG AATTTTGGAT CCCAAAACAG CTCAGAATCT GTCCATCTTT 
CTGGGATCAT ATCGCATGCC ATATGAAGAC ATAAGAAACG TTATTCTGGA GGTTAATGAA 
GACATGCTGA GTGAGGCTTT AATTCAGAAC CTTGTGAAAC ATCTTCCTGA GCAGAAGATA 
CTCAACGAAT TAGCAGAGCT TAAGAATGAA TATGATGACC TCTGTGAGCC TGAACAATTT 
GGAGTTGTGA TGAGCTCTGT GAAAATGTTA CAGCCTCGTC TCAGTAGTAT CCTGTTCAAG 
CTCACATTTG AAGAACACAT AAACAACATC AAACCAAGCA TCATAGCAGT AACTCTTGCC 
TGTGAAGAAC TGAAGAAAAG TGAAAGCTTT AACAGACTTT TAGAGTTAGT TCTTCTTGTT 
GGAAACTACA TGAACTCAGG CTCAAGAAAT GCCCAGTCTT TGGGATTTAA GATCAACTTC 
CTTTGTAAGA TCAGAGATAC TAAATCAGCG GATCAAAAAA CAACCCTTTT GCATTTTATT 
GCCGACATTT GTGAGGAAAA ATATCGAGAT ATCCTAAAAT TTCCTGAAGA ACTGGAACAC 
GTAGAAAGTG CAAGCAAAGT TTCAGCTCAA ATTCTCAAGA GCAACCTTGC ATCAATGGAA 
CAACAAATTG TTCATCTGGA ACGTGACATC AAGAAATTCC CCCAAGCAGA AAATCAACAC 
GATAAGTTTG TGGAAAAGAT GACCAGCTTT ACAAAGACTG CCCGAGAACA GTATGAAAAA 
CTCTCCACCA TGCACAACAA CATGATGAAG CTCTATGAGA ATCTTGGAGA ATACTTCATT 
TTTGACTCAA AGACAGTGAG CATAGAAGAG TTCTTTGGTG ATCTCAACAA CTTCCGAACT 
TTGTTTTTGG AAGCAGTGAG AGAAAACAAT AAGAGAAGAG AAATGGAAGA GAAGACCAGG 
AGGGCAAAAC TTGCAAAAGA GAAAGCTGAA CAAGAAAAGT TAGAACGCCA GAAGAAAAAG 
AAACAACTCA TTGATATAAA CAAAGAGGGT GATGAGACTG GTGTGATGGA TAATCTTCTA 
GAAGCCCTAC AATCAGGTGC AGCATTCAGA GACCGTCGAA AGCGGATTCC AAGGAATCCA 
GATAACAGAC GAGTACCTTT GGAAAGGTCA CGCTCTCGCC ACAATGGAGC TATCTCATCT 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIAPH2 ( NM_006729.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_006720.1 Homo sapiens diaphanous related formin 2 (DIAPH2), transcript variant 156, mRNA.

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CloneID	OHu18336
Clone ID Related Accession (Same CDS sequence)	NM_006729.4 , NM_006729.5
Accession Version	NM_006729.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3306bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	protein diaphanous homolog 2 isoform 156
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from Y15909.1, U69179.1, DB062196.1 and AL391821.7. On Nov 23, 2018 this sequence version replaced NM_006729.4. Transcript Variant: This variant (156) represents the longer transcript, and encodes the longer isoform (isoform 156). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y15909.1, SRR1803612.128120.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000324765.13/ ENSP00000321348.8 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCAGC CCGGGGCGGC GGCGTCGGGA GCGGGAGGCG GCAGCGAGGA ACCCGGTGGG 
GGCCGGAGCA ACAAGCGGAG CGCGGGGAAC CGGGCCGCCA ATGAAGAGGA AACGAAAAAC 
AAACCCAAAT TGAACATTCA AATAAAAACT TTGGCAGATG ATGTGCGTGA CCGAATTACA 
AGTTTTAGAA AATCTACTGT CAAAAAAGAA AAACCTCTTA TTCAACATCC TATTGATTCT 
CAAGTCGCGA TGAGTGAGTT TCCTGCAGCT CAGCCATTAT ATGATGAACG ATCTTTGAAT 
TTGTCAGAAA AGGAAGTATT GGATCTCTTT GAAAAAATGA TGGAGGACAT GAACCTTAAC 
GAAGAGAAAA AAGCTCCTTT ACGAAACAAA GACTTTACCA CCAAACGTGA GATGGTTGTC 
CAGTATATTT CTGCCACTGC CAAATCTGGT GGGCTGAAAA ACAGCAAACA TGAATGCACC 
CTGTCTTCAC AAGAATATGT TCATGAATTA CGATCGGGTA TATCAGATGA GAAACTTCTT 
AATTGCCTAG AATCCCTCAG GGTTTCTTTA ACCAGCAATC CGGTCAGCTG GGTTAACAAC 
TTTGGCCATG AAGGTCTTGG ACTCTTATTG GATGAGCTGG AAAAGCTTCT GGACAAAAAA 
CAGCAAGAAA ATATTGACAA GAAGAATCAG TATAAACTTA TTCAATGCCT CAAAGCATTT 
ATGAATAATA AGTTTGGATT ACAAAGGATT CTAGGAGATG AAAGAAGTCT TTTACTATTG 
GCAAGAGCAA TTGACCCCAA ACAACCCAAC ATGATGACTG AAATAGTAAA AATACTTTCT 
GCTATTTGCA TTGTTGGAGA AGAGAACATT CTAGATAAAC TTTTAGGGGC TATAACAACA 
GCAGCAGAAA GAAATAACAG GGAACGATTT TCACCAATTG TGGAAGGTTT AGAAAATCAG 
GAAGCCTTGC AATTACAGGT GGCCTGCATG CAGTTTATAA ATGCCCTTGT CACTTCTCCT 
TATGAGCTTG ATTTTCGAAT ACATTTAAGG AATGAATTCC TCCGTTCAGG ACTAAAAACA 
ATGTTACCAG ATCTAAAAGA AAAAGAGAAT GATGAGCTTG ATATTCAGTT GAAAGTATTT 
GATGAAAACA AAGAAGATGA CCTAACTGAA TTATCACACC GTCTCAATGA CATTCGAGCA 
GAAATGGATG ATATGAATGA AGTCTACCAT CTTCTATATA ATATGCTGAA GGACACTGCT 
GCTGAAAATT ACTTCTTATC TATTCTACAA CATTTTTTGC TTATCAGAAA TGATTATTAT 
ATCAGGCCAC AATATTATAA AATAATTGAG GAATGTGTTT CACAGATAGT GCTACACTGC 
AGTGGTATGG ATCCAGACTT CAAATACAGG CAAAGATTAG ACATCGATTT AACTCATCTG 
ATAGATTCTT GTGTGAACAA GGCGAAAGTT GAAGAAAGTG AACAAAAAGC TGCAGAGTTT 
TCAAAGAAGT TCGATGAAGA ATTCACAGCT CGACAGGAAG CTCAAGCAGA GCTTCAAAAA 
AGAGATGAGA AAATCAAAGA ACTTGAAGCA GAAATCCAGC AACTTCGAAC CCAGGCACAA 
GTACTCTCAA GTTCATCAGG AATTCCAGGT CCTCCTGCAG CACCTCCATT GCCAGGTGTA 
GGGCCGCCTC CACCACCACC CGCGCCACCT CTACCCGGAG GAGCTCCTCT TCCTCCTCCA 
CCACCTCCTT TACCTGGAAT GATGGGGATA CCACCACCAC CCCCACCACC ACTTTTATTT 
GGGGGACCTC CTCCACCACC ACCCCTTGGA GGAGTTCCTC CTCCCCCAGG AATATCACTT 
AATCTACCTT ATGGAATGAA GCAGAAAAAA ATGTATAAAC CTGAAGTGTC CATGAAGAGA 
ATCAATTGGT CAAAGATTGA ACCCACAGAA TTATCTGAGA ACTGTTTCTG GTTAAGAGTC 
AAAGAAGACA AGTTTGAGAA TCCAGATCTC TTTGCCAAAT TGGCATTGAA TTTTGCTACT 
CAGATAAAAG TTCAAAAGAA CGCAGAAGCA TTAGAAGAAA AGAAGACTGG GCCTACAAAG 
AAGAAAGTGA AAGAACTGAG AATTTTGGAT CCCAAAACAG CTCAGAATCT GTCCATCTTT 
CTGGGATCAT ATCGCATGCC ATATGAAGAC ATAAGAAACG TTATTCTGGA GGTTAATGAA 
GACATGCTGA GTGAGGCTTT AATTCAGAAC CTTGTGAAAC ATCTTCCTGA GCAGAAGATA 
CTCAACGAAT TAGCAGAGCT TAAGAATGAA TATGATGACC TCTGTGAGCC TGAACAATTT 
GGAGTTGTGA TGAGCTCTGT GAAAATGTTA CAGCCTCGTC TCAGTAGTAT CCTGTTCAAG 
CTCACATTTG AAGAACACAT AAACAACATC AAACCAAGCA TCATAGCAGT AACTCTTGCC 
TGTGAAGAAC TGAAGAAAAG TGAAAGCTTT AACAGACTTT TAGAGTTAGT TCTTCTTGTT 
GGAAACTACA TGAACTCAGG CTCAAGAAAT GCCCAGTCTT TGGGATTTAA GATCAACTTC 
CTTTGTAAGA TCAGAGATAC TAAATCAGCG GATCAAAAAA CAACCCTTTT GCATTTTATT 
GCCGACATTT GTGAGGAAAA ATATCGAGAT ATCCTAAAAT TTCCTGAAGA ACTGGAACAC 
GTAGAAAGTG CAAGCAAAGT TTCAGCTCAA ATTCTCAAGA GCAACCTTGC ATCAATGGAA 
CAACAAATTG TTCATCTGGA ACGTGACATC AAGAAATTCC CCCAAGCAGA AAATCAACAC 
GATAAGTTTG TGGAAAAGAT GACCAGCTTT ACAAAGACTG CCCGAGAACA GTATGAAAAA 
CTCTCCACCA TGCACAACAA CATGATGAAG CTCTATGAGA ATCTTGGAGA ATACTTCATT 
TTTGACTCAA AGACAGTGAG CATAGAAGAG TTCTTTGGTG ATCTCAACAA CTTCCGAACT 
TTGTTTTTGG AAGCAGTGAG AGAAAACAAT AAGAGAAGAG AAATGGAAGA GAAGACCAGG 
AGGGCAAAAC TTGCAAAAGA GAAAGCTGAA CAAGAAAAGT TAGAACGCCA GAAGAAAAAG 
AAACAACTCA TTGATATAAA CAAAGAGGGT GATGAGACTG GTGTGATGGA TAATCTTCTA 
GAAGCCCTAC AATCAGGTGC AGCATTCAGA GACCGTCGAA AGCGGATTCC AAGGAATCCA 
GATAACAGAC GAGTACCTTT GGAAAGGTCA CGCTCTCGCC ACAATGGAGC TATCTCATCT 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006720.1
CDS	218..3523
Translation	MEQPGAAASGAGGGSEEPGGGRSNKRSAGNRAANEEETKNKPKLNIQIKTLADDVRDRITSFRKSTVKKEKPLIQHPIDSQVAMSEFPAAQPLYDERSLNLSEKEVLDLFEKMMEDMNLNEEKKAPLRNKDFTTKREMVVQYISATAKSGGLKNSKHECTLSSQEYVHELRSGISDEKLLNCLESLRVSLTSNPVSWVNNFGHEGLGLLLDELEKLLDKKQQENIDKKNQYKLIQCLKAFMNNKFGLQRILGDERSLLLLARAIDPKQPNMMTEIVKILSAICIVGEENILDKLLGAITTAAERNNRERFSPIVEGLENQEALQLQVACMQFINALVTSPYELDFRIHLRNEFLRSGLKTMLPDLKEKENDELDIQLKVFDENKEDDLTELSHRLNDIRAEMDDMNEVYHLLYNMLKDTAAENYFLSILQHFLLIRNDYYIRPQYYKIIEECVSQIVLHCSGMDPDFKYRQRLDIDLTHLIDSCVNKAKVEESEQKAAEFSKKFDEEFTARQEAQAELQKRDEKIKELEAEIQQLRTQAQVLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGVPPPPGISLNLPYGMKQKKMYKPEVSMKRINWSKIEPTELSENCFWLRVKEDKFENPDLFAKLALNFATQIKVQKNAEALEEKKTGPTKKKVKELRILDPKTAQNLSIFLGSYRMPYEDIRNVILEVNEDMLSEALIQNLVKHLPEQKILNELAELKNEYDDLCEPEQFGVVMSSVKMLQPRLSSILFKLTFEEHINNIKPSIIAVTLACEELKKSESFNRLLELVLLVGNYMNSGSRNAQSLGFKINFLCKIRDTKSADQKTTLLHFIADICEEKYRDILKFPEELEHVESASKVSAQILKSNLASMEQQIVHLERDIKKFPQAENQHDKFVEKMTSFTKTAREQYEKLSTMHNNMMKLYENLGEYFIFDSKTVSIEEFFGDLNNFRTLFLEAVRENNKRREMEEKTRRAKLAKEKAEQEKLERQKKKKQLIDINKEGDETGVMDNLLEALQSGAAFRDRRKRIPRNPDNRRVPLERSRSRHNGAISSK

Target ORF information:

RefSeq Version	NM_006729.5
Organism	Homo sapiens(human)
Definition	Homo sapiens diaphanous related formin 2 (DIAPH2), transcript variant 156, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006729.5

ORF Insert Sequence:

ATGGAGCAGC CCGGGGCGGC GGCGTCGGGA GCGGGAGGCG GCAGCGAGGA ACCCGGTGGG 
GGCCGGAGCA ACAAGCGGAG CGCGGGGAAC CGGGCCGCCA ATGAAGAGGA AACGAAAAAC 
AAACCCAAAT TGAACATTCA AATAAAAACT TTGGCAGATG ATGTGCGTGA CCGAATTACA 
AGTTTTAGAA AATCTACTGT CAAAAAAGAA AAACCTCTTA TTCAACATCC TATTGATTCT 
CAAGTCGCGA TGAGTGAGTT TCCTGCAGCT CAGCCATTAT ATGATGAACG ATCTTTGAAT 
TTGTCAGAAA AGGAAGTATT GGATCTCTTT GAAAAAATGA TGGAGGACAT GAACCTTAAC 
GAAGAGAAAA AAGCTCCTTT ACGAAACAAA GACTTTACCA CCAAACGTGA GATGGTTGTC 
CAGTATATTT CTGCCACTGC CAAATCTGGT GGGCTGAAAA ACAGCAAACA TGAATGCACC 
CTGTCTTCAC AAGAATATGT TCATGAATTA CGATCGGGTA TATCAGATGA GAAACTTCTT 
AATTGCCTAG AATCCCTCAG GGTTTCTTTA ACCAGCAATC CGGTCAGCTG GGTTAACAAC 
TTTGGCCATG AAGGTCTTGG ACTCTTATTG GATGAGCTGG AAAAGCTTCT GGACAAAAAA 
CAGCAAGAAA ATATTGACAA GAAGAATCAG TATAAACTTA TTCAATGCCT CAAAGCATTT 
ATGAATAATA AGTTTGGATT ACAAAGGATT CTAGGAGATG AAAGAAGTCT TTTACTATTG 
GCAAGAGCAA TTGACCCCAA ACAACCCAAC ATGATGACTG AAATAGTAAA AATACTTTCT 
GCTATTTGCA TTGTTGGAGA AGAGAACATT CTAGATAAAC TTTTAGGGGC TATAACAACA 
GCAGCAGAAA GAAATAACAG GGAACGATTT TCACCAATTG TGGAAGGTTT AGAAAATCAG 
GAAGCCTTGC AATTACAGGT GGCCTGCATG CAGTTTATAA ATGCCCTTGT CACTTCTCCT 
TATGAGCTTG ATTTTCGAAT ACATTTAAGG AATGAATTCC TCCGTTCAGG ACTAAAAACA 
ATGTTACCAG ATCTAAAAGA AAAAGAGAAT GATGAGCTTG ATATTCAGTT GAAAGTATTT 
GATGAAAACA AAGAAGATGA CCTAACTGAA TTATCACACC GTCTCAATGA CATTCGAGCA 
GAAATGGATG ATATGAATGA AGTCTACCAT CTTCTATATA ATATGCTGAA GGACACTGCT 
GCTGAAAATT ACTTCTTATC TATTCTACAA CATTTTTTGC TTATCAGAAA TGATTATTAT 
ATCAGGCCAC AATATTATAA AATAATTGAG GAATGTGTTT CACAGATAGT GCTACACTGC 
AGTGGTATGG ATCCAGACTT CAAATACAGG CAAAGATTAG ACATCGATTT AACTCATCTG 
ATAGATTCTT GTGTGAACAA GGCGAAAGTT GAAGAAAGTG AACAAAAAGC TGCAGAGTTT 
TCAAAGAAGT TCGATGAAGA ATTCACAGCT CGACAGGAAG CTCAAGCAGA GCTTCAAAAA 
AGAGATGAGA AAATCAAAGA ACTTGAAGCA GAAATCCAGC AACTTCGAAC CCAGGCACAA 
GTACTCTCAA GTTCATCAGG AATTCCAGGT CCTCCTGCAG CACCTCCATT GCCAGGTGTA 
GGGCCGCCTC CACCACCACC CGCGCCACCT CTACCCGGAG GAGCTCCTCT TCCTCCTCCA 
CCACCTCCTT TACCTGGAAT GATGGGGATA CCACCACCAC CCCCACCACC ACTTTTATTT 
GGGGGACCTC CTCCACCACC ACCCCTTGGA GGAGTTCCTC CTCCCCCAGG AATATCACTT 
AATCTACCTT ATGGAATGAA GCAGAAAAAA ATGTATAAAC CTGAAGTGTC CATGAAGAGA 
ATCAATTGGT CAAAGATTGA ACCCACAGAA TTATCTGAGA ACTGTTTCTG GTTAAGAGTC 
AAAGAAGACA AGTTTGAGAA TCCAGATCTC TTTGCCAAAT TGGCATTGAA TTTTGCTACT 
CAGATAAAAG TTCAAAAGAA CGCAGAAGCA TTAGAAGAAA AGAAGACTGG GCCTACAAAG 
AAGAAAGTGA AAGAACTGAG AATTTTGGAT CCCAAAACAG CTCAGAATCT GTCCATCTTT 
CTGGGATCAT ATCGCATGCC ATATGAAGAC ATAAGAAACG TTATTCTGGA GGTTAATGAA 
GACATGCTGA GTGAGGCTTT AATTCAGAAC CTTGTGAAAC ATCTTCCTGA GCAGAAGATA 
CTCAACGAAT TAGCAGAGCT TAAGAATGAA TATGATGACC TCTGTGAGCC TGAACAATTT 
GGAGTTGTGA TGAGCTCTGT GAAAATGTTA CAGCCTCGTC TCAGTAGTAT CCTGTTCAAG 
CTCACATTTG AAGAACACAT AAACAACATC AAACCAAGCA TCATAGCAGT AACTCTTGCC 
TGTGAAGAAC TGAAGAAAAG TGAAAGCTTT AACAGACTTT TAGAGTTAGT TCTTCTTGTT 
GGAAACTACA TGAACTCAGG CTCAAGAAAT GCCCAGTCTT TGGGATTTAA GATCAACTTC 
CTTTGTAAGA TCAGAGATAC TAAATCAGCG GATCAAAAAA CAACCCTTTT GCATTTTATT 
GCCGACATTT GTGAGGAAAA ATATCGAGAT ATCCTAAAAT TTCCTGAAGA ACTGGAACAC 
GTAGAAAGTG CAAGCAAAGT TTCAGCTCAA ATTCTCAAGA GCAACCTTGC ATCAATGGAA 
CAACAAATTG TTCATCTGGA ACGTGACATC AAGAAATTCC CCCAAGCAGA AAATCAACAC 
GATAAGTTTG TGGAAAAGAT GACCAGCTTT ACAAAGACTG CCCGAGAACA GTATGAAAAA 
CTCTCCACCA TGCACAACAA CATGATGAAG CTCTATGAGA ATCTTGGAGA ATACTTCATT 
TTTGACTCAA AGACAGTGAG CATAGAAGAG TTCTTTGGTG ATCTCAACAA CTTCCGAACT 
TTGTTTTTGG AAGCAGTGAG AGAAAACAAT AAGAGAAGAG AAATGGAAGA GAAGACCAGG 
AGGGCAAAAC TTGCAAAAGA GAAAGCTGAA CAAGAAAAGT TAGAACGCCA GAAGAAAAAG 
AAACAACTCA TTGATATAAA CAAAGAGGGT GATGAGACTG GTGTGATGGA TAATCTTCTA 
GAAGCCCTAC AATCAGGTGC AGCATTCAGA GACCGTCGAA AGCGGATTCC AAGGAATCCA 
GATAACAGAC GAGTACCTTT GGAAAGGTCA CGCTCTCGCC ACAATGGAGC TATCTCATCT 
AAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Distinct functions of diaphanous-related formins regulate HIV-1 uncoating and transport.
Proceedings of the National Academy of Sciences of the United States of America114(33)E6932-E6941(2017 Aug)
Delaney MK,Malikov V,Chai Q,Zhao G,Naghavi MH

Essential and nonredundant roles for Diaphanous formins in cortical microtubule capture and directed cell migration.
Molecular biology of the cell25(5)658-68(2014 Mar)
Daou P,Hasan S,Breitsprecher D,Baudelet E,Camoin L,Audebert S,Goode BL,Badache A

Identification of genes promoting skin youthfulness by genome-wide association study.
The Journal of investigative dermatology134(3)651-657(2014 Mar)
Chang ALS,Atzmon G,Bergman A,Brugmann S,Atwood SX,Chang HY,Barzilai N

Inverted formin 2 regulates actin dynamics by antagonizing Rho/diaphanous-related formin signaling.
Journal of the American Society of Nephrology : JASN24(6)917-29(2013 May)
Sun H,Schlondorff J,Higgs HN,Pollak MR

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DIAPH2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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