DHCR24 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DHCR24
Entrez Gene ID	1718
Full Name	24-dehydrocholesterol reductase
Synonyms	DCE,Nbla03646,SELADIN1,seladin-1
General protein information	Preferred Names 24-dehydrocholesterol reductase Names delta(24)-sterol reductase 3 beta-hydroxysterol delta 24-reductase desmosterol-to-cholesterol enzyme diminuto/dwarf1 homolog seladin 1 selective AD indicator 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p32.3
Summary	This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq, Jul 2008].
Disorder MIM:	606418
Disorder Html:	Desmosterolosis, 602398 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_014762.4	NP_055577.1	delta(24)-sterol reductase precursor
NM_014762.3	NP_055577.1	delta(24)-sterol reductase precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	DHCR24	XP_546693.4
Mus musculus (house mouse)	Dhcr24	NP_444502.2
Gallus gallus (chicken)	DHCR24	NP_001026459.1
Magnaporthe oryzae (rice blast fungus)	MGG_16834	XP_003712445.1
Homo sapiens (human)	DHCR24	NP_055577.1
Xenopus tropicalis (tropical clawed frog)	dhcr24	NP_001016800.1
	DHCR24	XP_001108186.2
Rattus norvegicus (Norway rat)	Dhcr24	NP_001073617.1
Arabidopsis thaliana (thale cress)	DWF1	NP_850616.1
Pan troglodytes (chimpanzee)	DHCR24	XP_001153930.1
Bos taurus (cattle)	DHCR24	NP_001096746.1
Danio rerio (zebrafish)	dhcr24	NP_001008645.1
Caenorhabditis elegans (roundworm)	F52H2.6	NP_508463.1
Oryza sativa (rice)	Os10g0397400	NP_001064534.1

Gene Ontology
Bibliography

Related articles in PubMed

Desmosterolosis presenting with multiple congenital anomalies.
Rohanizadegan M, Sacharow S
European journal of medical genetics(2017 Nov)

Maternal eating disorders affect offspring cord blood DNA methylation: a prospective study.
Kazmi N, Gaunt TR, Relton C, Micali N
Clinical epigenetics9120(2017)

Cholesterol Synthetase DHCR24 Induced by Insulin Aggravates Cancer Invasion and Progesterone Resistance in Endometrial Carcinoma.
Dai M, Zhu XL, Liu F, Xu QY, Ge QL, Jiang SH, Yang XM, Li J, Wang YH, Wu QK, Ai ZH, Teng YC, Zhang ZG
Scientific reports741404(2017 Jan)

DHCR24 associates strongly with the endoplasmic reticulum beyond predicted membrane domains: implications for the activities of this multi-functional enzyme.
Zerenturk EJ, Sharpe LJ, Brown AJ
Bioscience reports34(2)(2014 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

DHCR24 auto-antibody represents a potential noninvasive biomarker for hepatitis C virus-related liver disease and may facilitate the diagnosis of PIVKA-II and AFP-negative hepatocellular carcinoma.
Title: Serum DHCR24 Auto-antibody as a new Biomarker for Progression of Hepatitis C.

physical and functional interaction between DHCR24 and DHCR7
Title: The terminal enzymes of cholesterol synthesis, DHCR24 and DHCR7, interact physically and functionally.

In vitro experiments showed that DHCR24 overexpression induced tumor proliferation.
Title: DHCR24 is an independent predictor of progression in patients with non-muscle-invasive urothelial carcinoma, and its functional role is involved in the aggressive properties of urothelial carcinoma cells.

Data (including data from studies using RNA from post-mortem brain tissue) suggest that expression of DHCR24 is up-regulated in parietal cortex of patients with Huntington's disease as compared to control subjects.
Title: Altered expression of 3-betahydroxysterol delta-24-reductase/selective Alzheimer's disease indicator-1 gene in Huntington's disease models.

the expanding database of post-translational modifications will be a valuable resource for mapping the topology of membrane-associated proteins, such as DHCR24, that is, flagging cytosolic residues accessible to modifying enzymes such as kinases and ubiquitin ligases.
Title: DHCR24 associates strongly with the endoplasmic reticulum beyond predicted membrane domains: implications for the activities of this multi-functional enzyme.

The following DHCR24 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DHCR24 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18019	NM_014762.4 Latest version!	Homo sapiens 24-dehydrocholesterol reductase (DHCR24), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu18019	NM_014762.3	Homo sapiens 24-dehydrocholesterol reductase (DHCR24), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DHCR24 ( NM_014762.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055577.1 Homo sapiens 24-dehydrocholesterol reductase (DHCR24), mRNA.

Price & Availability↑

CloneID	OHu18019
Clone ID Related Accession (Same CDS sequence)	NM_014762.4 , NM_014762.3
Accession Version	NM_014762.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1551bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-23
Organism	Homo sapiens(human)
Product	delta(24)-sterol reductase precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP200916.1, BC004375.1 and AC096536.2. This sequence is a reference standard in the RefSeqGene project. On Aug 8, 2018 this sequence version replaced NM_014762.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.130995.1, SRR1803616.25944.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145544, SAMEA2155770 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000371269.9/ ENSP00000360316.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGCCCG CCGTGTCGCT GGCCGTGTGC GCGCTGCTCT TCCTGCTGTG GGTGCGCCTG 
AAGGGGCTGG AGTTCGTGCT CATCCACCAG CGCTGGGTGT TCGTGTGCCT CTTCCTCCTG 
CCGCTCTCGC TTATCTTCGA TATCTACTAC TACGTGCGCG CCTGGGTGGT GTTCAAGCTC 
AGCAGCGCTC CGCGCCTGCA CGAGCAGCGC GTGCGGGACA TCCAGAAGCA GGTGCGGGAA 
TGGAAGGAGC AGGGTAGCAA GACCTTCATG TGCACGGGGC GCCCTGGCTG GCTCACTGTC 
TCACTACGTG TCGGGAAGTA CAAGAAGACA CACAAAAACA TCATGATCAA CCTGATGGAC 
ATTCTGGAAG TGGACACCAA GAAACAGATT GTCCGTGTGG AGCCCTTGGT GACCATGGGC 
CAGGTGACTG CCCTGCTGAC CTCCATTGGC TGGACTCTCC CCGTGTTGCC TGAGCTTGAT 
GACCTCACAG TGGGGGGCTT GATCATGGGC ACAGGCATCG AGTCATCATC CCACAAGTAC 
GGCCTGTTCC AACACATCTG CACTGCTTAC GAGCTGGTCC TGGCTGATGG CAGCTTTGTG 
CGATGCACTC CGTCCGAAAA CTCAGACCTG TTCTATGCCG TACCCTGGTC CTGTGGGACG 
CTGGGTTTCC TGGTGGCCGC TGAGATCCGC ATCATCCCTG CCAAGAAGTA CGTCAAGCTG 
CGTTTCGAGC CAGTGCGGGG CCTGGAGGCT ATCTGTGCCA AGTTCACCCA CGAGTCCCAG 
CGGCAGGAGA ACCACTTCGT GGAAGGGCTG CTCTACTCCC TGGATGAGGC TGTCATTATG 
ACAGGGGTCA TGACAGATGA GGCAGAGCCC AGCAAGCTGA ATAGCATTGG CAATTACTAC 
AAGCCGTGGT TCTTTAAGCA TGTGGAGAAC TATCTGAAGA CAAACCGAGA GGGCCTGGAG 
TACATTCCCT TGAGACACTA CTACCACCGC CACACGCGCA GCATCTTCTG GGAGCTCCAG 
GACATTATCC CCTTTGGCAA CAACCCCATC TTCCGCTACC TCTTTGGCTG GATGGTGCCT 
CCCAAGATCT CCCTCCTGAA GCTGACCCAG GGTGAGACCC TGCGCAAGCT GTACGAGCAG 
CACCACGTGG TGCAGGACAT GCTGGTGCCC ATGAAGTGCC TGCAGCAGGC CCTGCACACC 
TTCCAAAACG ACATCCACGT CTACCCCATC TGGCTGTGTC CGTTCATCCT GCCCAGCCAG 
CCAGGCCTAG TGCACCCCAA AGGAAATGAG GCAGAGCTCT ACATCGACAT TGGAGCATAT 
GGGGAGCCGC GTGTGAAACA CTTTGAAGCC AGGTCCTGCA TGAGGCAGCT GGAGAAGTTT 
GTCCGCAGCG TGCATGGCTT CCAGATGCTG TATGCCGACT GCTACATGAA CCGGGAGGAG 
TTCTGGGAGA TGTTTGATGG CTCCTTGTAC CACAAGCTGC GAGAGAAGCT GGGTTGCCAG 
GACGCCTTCC CCGAGGTGTA CGACAAGATC TGCAAGGCCG CCAGGCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055577.1
CDS	77..1627
Translation	MEPAVSLAVCALLFLLWVRLKGLEFVLIHQRWVFVCLFLLPLSLIFDIYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKEQGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALLTSIGWTLPVLPELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELVLADGSFVRCTPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICAKFTHESQRQENHFVEGLLYSLDEAVIMTGVMTDEAEPSKLNSIGNYYKPWFFKHVENYLKTNREGLEYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCLQQALHTFQNDIHVYPIWLCPFILPSQPGLVHPKGNEAELYIDIGAYGEPRVKHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLREKLGCQDAFPEVYDKICKAARH

Target ORF information:

RefSeq Version	NM_014762.4
Organism	Homo sapiens(human)
Definition	Homo sapiens 24-dehydrocholesterol reductase (DHCR24), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014762.4

ORF Insert Sequence:

ATGGAGCCCG CCGTGTCGCT GGCCGTGTGC GCGCTGCTCT TCCTGCTGTG GGTGCGCCTG 
AAGGGGCTGG AGTTCGTGCT CATCCACCAG CGCTGGGTGT TCGTGTGCCT CTTCCTCCTG 
CCGCTCTCGC TTATCTTCGA TATCTACTAC TACGTGCGCG CCTGGGTGGT GTTCAAGCTC 
AGCAGCGCTC CGCGCCTGCA CGAGCAGCGC GTGCGGGACA TCCAGAAGCA GGTGCGGGAA 
TGGAAGGAGC AGGGTAGCAA GACCTTCATG TGCACGGGGC GCCCTGGCTG GCTCACTGTC 
TCACTACGTG TCGGGAAGTA CAAGAAGACA CACAAAAACA TCATGATCAA CCTGATGGAC 
ATTCTGGAAG TGGACACCAA GAAACAGATT GTCCGTGTGG AGCCCTTGGT GACCATGGGC 
CAGGTGACTG CCCTGCTGAC CTCCATTGGC TGGACTCTCC CCGTGTTGCC TGAGCTTGAT 
GACCTCACAG TGGGGGGCTT GATCATGGGC ACAGGCATCG AGTCATCATC CCACAAGTAC 
GGCCTGTTCC AACACATCTG CACTGCTTAC GAGCTGGTCC TGGCTGATGG CAGCTTTGTG 
CGATGCACTC CGTCCGAAAA CTCAGACCTG TTCTATGCCG TACCCTGGTC CTGTGGGACG 
CTGGGTTTCC TGGTGGCCGC TGAGATCCGC ATCATCCCTG CCAAGAAGTA CGTCAAGCTG 
CGTTTCGAGC CAGTGCGGGG CCTGGAGGCT ATCTGTGCCA AGTTCACCCA CGAGTCCCAG 
CGGCAGGAGA ACCACTTCGT GGAAGGGCTG CTCTACTCCC TGGATGAGGC TGTCATTATG 
ACAGGGGTCA TGACAGATGA GGCAGAGCCC AGCAAGCTGA ATAGCATTGG CAATTACTAC 
AAGCCGTGGT TCTTTAAGCA TGTGGAGAAC TATCTGAAGA CAAACCGAGA GGGCCTGGAG 
TACATTCCCT TGAGACACTA CTACCACCGC CACACGCGCA GCATCTTCTG GGAGCTCCAG 
GACATTATCC CCTTTGGCAA CAACCCCATC TTCCGCTACC TCTTTGGCTG GATGGTGCCT 
CCCAAGATCT CCCTCCTGAA GCTGACCCAG GGTGAGACCC TGCGCAAGCT GTACGAGCAG 
CACCACGTGG TGCAGGACAT GCTGGTGCCC ATGAAGTGCC TGCAGCAGGC CCTGCACACC 
TTCCAAAACG ACATCCACGT CTACCCCATC TGGCTGTGTC CGTTCATCCT GCCCAGCCAG 
CCAGGCCTAG TGCACCCCAA AGGAAATGAG GCAGAGCTCT ACATCGACAT TGGAGCATAT 
GGGGAGCCGC GTGTGAAACA CTTTGAAGCC AGGTCCTGCA TGAGGCAGCT GGAGAAGTTT 
GTCCGCAGCG TGCATGGCTT CCAGATGCTG TATGCCGACT GCTACATGAA CCGGGAGGAG 
TTCTGGGAGA TGTTTGATGG CTCCTTGTAC CACAAGCTGC GAGAGAAGCT GGGTTGCCAG 
GACGCCTTCC CCGAGGTGTA CGACAAGATC TGCAAGGCCG CCAGGCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DHCR24 ( NM_014762.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055577.1 Homo sapiens 24-dehydrocholesterol reductase (DHCR24), mRNA.

Price & Availability↑

CloneID	OHu18019
Clone ID Related Accession (Same CDS sequence)	NM_014762.4 , NM_014762.3
Accession Version	NM_014762.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1551bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	delta(24)-sterol reductase precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP200916.1, BC004375.1 and AC096536.2. This sequence is a reference standard in the RefSeqGene project. On Sep 7, 2006 this sequence version replaced NM_014762.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.247001.1, SRR1803617.238867.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145544, SAMEA2155770 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCCCG CCGTGTCGCT GGCCGTGTGC GCGCTGCTCT TCCTGCTGTG GGTGCGCCTG 
AAGGGGCTGG AGTTCGTGCT CATCCACCAG CGCTGGGTGT TCGTGTGCCT CTTCCTCCTG 
CCGCTCTCGC TTATCTTCGA TATCTACTAC TACGTGCGCG CCTGGGTGGT GTTCAAGCTC 
AGCAGCGCTC CGCGCCTGCA CGAGCAGCGC GTGCGGGACA TCCAGAAGCA GGTGCGGGAA 
TGGAAGGAGC AGGGTAGCAA GACCTTCATG TGCACGGGGC GCCCTGGCTG GCTCACTGTC 
TCACTACGTG TCGGGAAGTA CAAGAAGACA CACAAAAACA TCATGATCAA CCTGATGGAC 
ATTCTGGAAG TGGACACCAA GAAACAGATT GTCCGTGTGG AGCCCTTGGT GACCATGGGC 
CAGGTGACTG CCCTGCTGAC CTCCATTGGC TGGACTCTCC CCGTGTTGCC TGAGCTTGAT 
GACCTCACAG TGGGGGGCTT GATCATGGGC ACAGGCATCG AGTCATCATC CCACAAGTAC 
GGCCTGTTCC AACACATCTG CACTGCTTAC GAGCTGGTCC TGGCTGATGG CAGCTTTGTG 
CGATGCACTC CGTCCGAAAA CTCAGACCTG TTCTATGCCG TACCCTGGTC CTGTGGGACG 
CTGGGTTTCC TGGTGGCCGC TGAGATCCGC ATCATCCCTG CCAAGAAGTA CGTCAAGCTG 
CGTTTCGAGC CAGTGCGGGG CCTGGAGGCT ATCTGTGCCA AGTTCACCCA CGAGTCCCAG 
CGGCAGGAGA ACCACTTCGT GGAAGGGCTG CTCTACTCCC TGGATGAGGC TGTCATTATG 
ACAGGGGTCA TGACAGATGA GGCAGAGCCC AGCAAGCTGA ATAGCATTGG CAATTACTAC 
AAGCCGTGGT TCTTTAAGCA TGTGGAGAAC TATCTGAAGA CAAACCGAGA GGGCCTGGAG 
TACATTCCCT TGAGACACTA CTACCACCGC CACACGCGCA GCATCTTCTG GGAGCTCCAG 
GACATTATCC CCTTTGGCAA CAACCCCATC TTCCGCTACC TCTTTGGCTG GATGGTGCCT 
CCCAAGATCT CCCTCCTGAA GCTGACCCAG GGTGAGACCC TGCGCAAGCT GTACGAGCAG 
CACCACGTGG TGCAGGACAT GCTGGTGCCC ATGAAGTGCC TGCAGCAGGC CCTGCACACC 
TTCCAAAACG ACATCCACGT CTACCCCATC TGGCTGTGTC CGTTCATCCT GCCCAGCCAG 
CCAGGCCTAG TGCACCCCAA AGGAAATGAG GCAGAGCTCT ACATCGACAT TGGAGCATAT 
GGGGAGCCGC GTGTGAAACA CTTTGAAGCC AGGTCCTGCA TGAGGCAGCT GGAGAAGTTT 
GTCCGCAGCG TGCATGGCTT CCAGATGCTG TATGCCGACT GCTACATGAA CCGGGAGGAG 
TTCTGGGAGA TGTTTGATGG CTCCTTGTAC CACAAGCTGC GAGAGAAGCT GGGTTGCCAG 
GACGCCTTCC CCGAGGTGTA CGACAAGATC TGCAAGGCCG CCAGGCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055577.1
CDS	130..1680
Translation	MEPAVSLAVCALLFLLWVRLKGLEFVLIHQRWVFVCLFLLPLSLIFDIYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKEQGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALLTSIGWTLPVLPELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELVLADGSFVRCTPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICAKFTHESQRQENHFVEGLLYSLDEAVIMTGVMTDEAEPSKLNSIGNYYKPWFFKHVENYLKTNREGLEYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCLQQALHTFQNDIHVYPIWLCPFILPSQPGLVHPKGNEAELYIDIGAYGEPRVKHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLREKLGCQDAFPEVYDKICKAARH

Target ORF information:

RefSeq Version	NM_014762.3
Organism	Homo sapiens(human)
Definition	Homo sapiens 24-dehydrocholesterol reductase (DHCR24), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014762.3

ORF Insert Sequence:

ATGGAGCCCG CCGTGTCGCT GGCCGTGTGC GCGCTGCTCT TCCTGCTGTG GGTGCGCCTG 
AAGGGGCTGG AGTTCGTGCT CATCCACCAG CGCTGGGTGT TCGTGTGCCT CTTCCTCCTG 
CCGCTCTCGC TTATCTTCGA TATCTACTAC TACGTGCGCG CCTGGGTGGT GTTCAAGCTC 
AGCAGCGCTC CGCGCCTGCA CGAGCAGCGC GTGCGGGACA TCCAGAAGCA GGTGCGGGAA 
TGGAAGGAGC AGGGTAGCAA GACCTTCATG TGCACGGGGC GCCCTGGCTG GCTCACTGTC 
TCACTACGTG TCGGGAAGTA CAAGAAGACA CACAAAAACA TCATGATCAA CCTGATGGAC 
ATTCTGGAAG TGGACACCAA GAAACAGATT GTCCGTGTGG AGCCCTTGGT GACCATGGGC 
CAGGTGACTG CCCTGCTGAC CTCCATTGGC TGGACTCTCC CCGTGTTGCC TGAGCTTGAT 
GACCTCACAG TGGGGGGCTT GATCATGGGC ACAGGCATCG AGTCATCATC CCACAAGTAC 
GGCCTGTTCC AACACATCTG CACTGCTTAC GAGCTGGTCC TGGCTGATGG CAGCTTTGTG 
CGATGCACTC CGTCCGAAAA CTCAGACCTG TTCTATGCCG TACCCTGGTC CTGTGGGACG 
CTGGGTTTCC TGGTGGCCGC TGAGATCCGC ATCATCCCTG CCAAGAAGTA CGTCAAGCTG 
CGTTTCGAGC CAGTGCGGGG CCTGGAGGCT ATCTGTGCCA AGTTCACCCA CGAGTCCCAG 
CGGCAGGAGA ACCACTTCGT GGAAGGGCTG CTCTACTCCC TGGATGAGGC TGTCATTATG 
ACAGGGGTCA TGACAGATGA GGCAGAGCCC AGCAAGCTGA ATAGCATTGG CAATTACTAC 
AAGCCGTGGT TCTTTAAGCA TGTGGAGAAC TATCTGAAGA CAAACCGAGA GGGCCTGGAG 
TACATTCCCT TGAGACACTA CTACCACCGC CACACGCGCA GCATCTTCTG GGAGCTCCAG 
GACATTATCC CCTTTGGCAA CAACCCCATC TTCCGCTACC TCTTTGGCTG GATGGTGCCT 
CCCAAGATCT CCCTCCTGAA GCTGACCCAG GGTGAGACCC TGCGCAAGCT GTACGAGCAG 
CACCACGTGG TGCAGGACAT GCTGGTGCCC ATGAAGTGCC TGCAGCAGGC CCTGCACACC 
TTCCAAAACG ACATCCACGT CTACCCCATC TGGCTGTGTC CGTTCATCCT GCCCAGCCAG 
CCAGGCCTAG TGCACCCCAA AGGAAATGAG GCAGAGCTCT ACATCGACAT TGGAGCATAT 
GGGGAGCCGC GTGTGAAACA CTTTGAAGCC AGGTCCTGCA TGAGGCAGCT GGAGAAGTTT 
GTCCGCAGCG TGCATGGCTT CCAGATGCTG TATGCCGACT GCTACATGAA CCGGGAGGAG 
TTCTGGGAGA TGTTTGATGG CTCCTTGTAC CACAAGCTGC GAGAGAAGCT GGGTTGCCAG 
GACGCCTTCC CCGAGGTGTA CGACAAGATC TGCAAGGCCG CCAGGCACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Desmosterolosis presenting with multiple congenital anomalies.
European journal of medical genetics(2017 Nov)
Rohanizadegan M,Sacharow S

Maternal eating disorders affect offspring cord blood DNA methylation: a prospective study.
Clinical epigenetics9120(2017)
Kazmi N,Gaunt TR,Relton C,Micali N

Cholesterol Synthetase DHCR24 Induced by Insulin Aggravates Cancer Invasion and Progesterone Resistance in Endometrial Carcinoma.
Scientific reports741404(2017 Jan)
Dai M,Zhu XL,Liu F,Xu QY,Ge QL,Jiang SH,Yang XM,Li J,Wang YH,Wu QK,Ai ZH,Teng YC,Zhang ZG

DHCR24 associates strongly with the endoplasmic reticulum beyond predicted membrane domains: implications for the activities of this multi-functional enzyme.
Bioscience reports34(2)(2014 Apr)
Zerenturk EJ,Sharpe LJ,Brown AJ

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

DHCR24 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報